CN101961465B - Chinese medicament for treating thrombus of portal system - Google Patents

Abstract

The invention belongs to the field of Chinese medicaments, and particularly discloses a Chinese medicament for treating thrombus of a portal system. The Chinese medicament is prepared from raw materials such as astragalus, Chinese atractylodes rhizome, Chinese angelica, phellodendron bark, coix seed, honeysuckle, figwort, centipede, leech, scorpion and liquorice root are used as raw materials in a certain weight ratio. The Chinese medicament has the advantages of simple preparation, good absorption effect, remarkable curative effect, no side effect and high safety, and is favorable for relieving symptoms of patients in time.

Description

The Chinese medicine of treatment portal system thrombosis

(1) technical field

The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine of treating the portal system thrombosis.

(2) background technology

Portal vein is the function blood vessel of liver, has collected the blood of digestive tract, spleen, pancreas, gallbladder, carries rich nutrient substances and is conveyed into liver, and except that former as the metabolizable energy of liver itself, also synthetic new material is supplied with the needs of body tissue.

Portal system thrombosis is a kind of common blood backflow obstacle property angiopathy; Modern medicine thinks that primary disease is by slow blood flow; Due to the reasons such as high blood coagulation and tunica intima damage, treatment at present is main with anticoagulant, thrombolytic, expansion blood vessel, antiinflammatory, how by intravenously administrable; Chinese traditional treatment is a principle with clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling all, adopt methods such as decoction oral or tablet be oral, but curative effect is all undesirable more.

(3) summary of the invention

The present invention provides the Chinese medicine of a kind of accessory treatment portal system thrombosis simple, evident in efficacy in order to remedy the deficiency of prior art.

The present invention realizes through following technical scheme:

A kind of Chinese medicine of treating the portal system thrombosis; It is characterized by, its active component is made up of the raw material of following parts by weight: 9～15 parts of the Radixs Astragali, 3～9 parts of Rhizoma Atractylodis, 6～12 parts of Radix Angelicae Sinensis, 3～9 parts of Cortex Phellodendris, 9～15 parts of Semen Coiciss, 10～20 parts of Flos Loniceraes, 9～15 parts of Radix Scrophulariaes, 1～5 part of Scolopendra, 3～9 parts of Hirudos, 1～5 part of Scorpio, 6～10 parts in Radix Glycyrrhizae.

The weight proportion of its preferred each active component is:

12 parts of the Radixs Astragali, 6 parts of Rhizoma Atractylodis, 12 parts of Radix Angelicae Sinensis, 6 parts of Cortex Phellodendris, 12 parts of Semen Coiciss, 18 parts of Flos Loniceraes, 12 parts of Radix Scrophulariaes, 3 parts of Scolopendras, 6 parts of Hirudos, 3 parts of Scorpios, 8 parts in Radix Glycyrrhizae.

Chinese medicine according to the invention is decoction.After each raw material cleaned up, being decocted in water for oral dose, every day potion, the preceding decoction being taken warmly of sleeping at twice.

The pharmaceutical characteristic of each medicine that the present invention adopts is following:

The Radix Astragali: benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.Cure mainly the card of all Qi and blood deficiencies, like diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back;

Rhizoma Atractylodis: drying damp and strengthening spleen, wind-damp dispelling makes eye bright.Cure mainly the spleen and stomach being stranded by dampness, the asthenia drowsiness, feeling of stuffiness in chest abdominal distention, inappetence, vomiting is had loose bowels, phlegm retention, damp-edema, it is wet to characterize folder, a heavy sensation of the body pain, the arthromyodynia domination of damp pathogen, podomere acid heavy the ， flaccidity of feet with lamenness, nyctalopia;

Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving is moisturized laxation.Cure mainly all diseases of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot gathers, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down;

Cortex Phellodendri: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， flaccidity of feet with lamenness, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema;

Semen Coicis: dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.Cure mainly edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana;

Flos Lonicerae: heat-clearing and toxic substances removing.Cure mainly the heating of affection due to external wind and heat or epidemic febrile disease, heatstroke, toxic-heat and blood stasis, carbuncle furuncle, sore throat, multiple infectious disease;

Radix Scrophulariae: removing heat from blood, nourishing YIN to lower pathogenic fire, detoxifcation.Cure mainly the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, scrofula sucutaneous nodule, skin sore;

Scolopendra: dispel the wind arresting convulsion, counteracting toxic substances, eliminating stagnation.Cure mainly apoplexy, infantile convulsion, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom;

Leech: dissipating blood stasis with potent drugs, the eliminating mass of stimulating the menstrual flow.Cure mainly blood stasis amenorrhea ， mass in the abdomen mass in the abdomen, traumatic injury;

Scorpio: relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.Cure mainly infantile convulsion and twitch epilepsy, apoplexy and hemiplegia; Mouth eye

is oblique; Migraine and general headache, rheumatoid arthritis stubborn, tetanus; The scrofula sucutaneous nodule, the rubella toxic swelling;

Radix Glycyrrhizae: with middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Process with controlling weakness of the spleen and stomach, the asthenia examination is burnt, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain carbuncle pyogenic infections from tumour or sore, infantile carbuncle, and medicine, things poisoning.

In the prescription, Rhizoma Atractylodis, Cortex Phellodendri, Semen Coicis, Flos Lonicerae are mainly used in heat clearing and damp drying, eliminating fire and detoxication; Add and join the Radix Astragali, Radix Angelicae Sinensis, Radix Scrophulariae, be used for benefiting qi and raising yang, enrich blood invigorate blood circulation, nourishing YIN to lower pathogenic fire; Join Scolopendra, Hirudo, Scorpio again, be mainly used in expelling wind for relieving convulsion, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation; Add with Radix Glycyrrhizae at last and be used for heat-clearing and toxic substances removing, alleviate pain relieving, coordinating the actions of various ingredients in a prescription, the toxicity of cushion and strong.

Clinical observation:

(1) clinical data

The inventor carries out clinical observation treatment to 50 routine portal system thrombosis patients, wherein male 30 examples, and women 20 examples, the age is between 63～80 years old.

(2) Therapeutic Method

After raw material of the present invention cleaned up, being decocted in water for oral dose, every day potion, the preceding decoction being taken warmly of sleeping at twice serve on six doses.

(3) curative effect determinate standard

Cure: symptom all disappears; Main physics and chemistry detects index and is normally.

Produce effects: symptomatology is eliminated or cardinal symptom is eliminated; It is normal basically that physics and chemistry detects index.

Effectively: cardinal symptom disappears basically; Main physics and chemistry detects index and makes moderate progress.

Invalid: main physics and chemistry detects index and the preceding no change of treatment.

(4) clinical effectiveness

Clinical cure 38 examples (76%), produce effects 8 examples (16%), effective 3 examples (6%), invalid 1 example (2%), total effective rate is 98%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, and is safe, helps sufferer and in time alleviates condition of illness.

(4) specific embodiment

Embodiment 1:

Get Radix Astragali 9g, Rhizoma Atractylodis 3g, Radix Angelicae Sinensis 6g, Cortex Phellodendri 3g, Semen Coicis 9g, Flos Lonicerae 10g, Radix Scrophulariae 9g, Scolopendra 1g, Hirudo 3g, Scorpio 1g, Radix Glycyrrhizae 6g, above-mentioned raw materials is cleaned up, the fried one-tenth decoction of water.

Usage and dosage: be decocted in water for oral dose, every day potion, the preceding decoction being taken warmly of sleeping at twice.

Embodiment 2:

Get Radix Astragali 15g, Rhizoma Atractylodis 9g, Radix Angelicae Sinensis 12g, Cortex Phellodendri 9g, Semen Coicis 15g, Flos Lonicerae 20g, Radix Scrophulariae 15g, Scolopendra 5g, Hirudo 9g, Scorpio 5g, Radix Glycyrrhizae 10g, above-mentioned raw materials is cleaned up, the fried one-tenth decoction of water.

Usage and dosage: be decocted in water for oral dose, every day potion, the preceding decoction being taken warmly of sleeping at twice.

Embodiment 3:

Get Radix Astragali 12g, Rhizoma Atractylodis 6g, Radix Angelicae Sinensis 12g, Cortex Phellodendri 6g, Semen Coicis 12g, Flos Lonicerae 18g, Radix Scrophulariae 12g, Scolopendra 3g, Hirudo 6g, Scorpio 3g, Radix Glycyrrhizae 8g, above-mentioned raw materials is cleaned up, the fried one-tenth decoction of water.

Usage and dosage: be decocted in water for oral dose, every day potion, the preceding decoction being taken warmly of sleeping at twice.

Claims (2)

1. Chinese medicine of treating the portal system thrombosis; It is characterized by, add decocting by the active component of following parts by weight and process decoction: 9～15 parts of the Radixs Astragali, 3～9 parts of Rhizoma Atractylodis, 6～12 parts of Radix Angelicae Sinensis, 3～9 parts of Cortex Phellodendris, 9～15 parts of Semen Coiciss, 10～20 parts of Flos Loniceraes, 9～15 parts of Radix Scrophulariaes, 1～5 part of Scolopendra, 3～9 parts of Hirudos, 1～5 part of Scorpio, 6～10 parts in Radix Glycyrrhizae.

2. the Chinese medicine of treatment portal system thrombosis according to claim 1; It is characterized by, add decocting by the active component of following parts by weight and process decoction: 12 parts of the Radixs Astragali, 6 parts of Rhizoma Atractylodis, 12 parts of Radix Angelicae Sinensis, 6 parts of Cortex Phellodendris, 12 parts of Semen Coiciss, 18 parts of Flos Loniceraes, 12 parts of Radix Scrophulariaes, 3 parts of Scolopendras, 6 parts of Hirudos, 3 parts of Scorpios, 8 parts in Radix Glycyrrhizae.