CN113769008A - Intestine-dredging granules - Google Patents
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Abstract
The bowel-relaxing granule comprises the following components: radix astragali, radix codonopsis, rhizoma atractylodis macrocephalae, coptis chinensis, flos sophorae, paris polyphylla, semen pruni, herba cistanches, radix rehmanniae, radix notoginseng, fructus cannabis, cortex moutan, radix glycyrrhizae preparata, cortex magnoliae officinalis and fructus aurantii immaturus. Tongchun granule has effects of invigorating spleen and replenishing qi, warming kidney and replenishing vital essence, and loosening bowel to relieve constipation. It is suitable for treating habitual constipation, constipation of the elderly, hemorrhoid constipation, puerperal constipation, and constipation after anorectal operation due to spleen qi deficiency, intestinal dryness and heat accumulation, body fluid deficiency, and kidney yang deficiency.
Description
Technical Field
The invention relates to the field of intestinal tract medicines, in particular to intestinal tract dredging granules.
Background
The constipation of the old people in China is as high as 15% -20%, and the incidence of the constipation is obviously increased along with the increase of the age of women than men. The classification of constipation is classified into organic and functional constipation according to the existence of organic lesions, and acute and chronic constipation according to the disease course or the disease starting mode, generally speaking, the constipation is chronic constipation after more than 12 weeks, the pathogenesis of the constipation is functional, and the pathogenesis of the constipation is inflammatory bowel disease, although the causes are different, the pathogenesis is different (colonic anal diseases, intestinal diseases, bad living habits, social and psychological factors), but as in Huangdi's internal classic, "vital qi exists in the body resistance, the pathogenic factors cannot be dry, the qi must be deficient", so the regulation of yin and yang is a key step under the condition that the organic lesions are eliminated in the whole disease development stage. For the treatment of constipation, attention should be paid to distinguishing deficiency from excess, differentiating syndromes and seeking causes, examining the treatment of causes and not being able to be put together, different treatments should be selected according to different types of constipation, and diet therapy, life adjustment and the like should be combined, which are all favorable for the treatment and recovery of constipation.
The medicine on the market similar to the bowel-relaxing granules at present is a fructus cannabis intestine-relaxing pill, the prescription of which comprises fructus cannabis, bitter apricot seed (peeled and fried), rhubarb, costustoot, dried orange peel, white paeony root and the like, and the medicine is clinically used for treating gastrointestinal heat accumulation, fullness and distention in chest and abdomen, constipation and the like. The prescription of the hemp seed spleen-nourishing pill comprises rhubarb (prepared), fructus cannabis, angelica, ginger-processed magnolia officinalis, fried bitter apricot seed, wheat bran immature bitter orange, bunge cherry seed, white paeony root and the like, and is clinically used for constipation caused by gastrointestinal heat accumulation, intestinal dryness and body fluid deficiency. The desert cistanche oral liquid for relaxing bowels is prepared with desert cistanche, fleeceflower root, immature bitter orange, honey and other Chinese medicinal materials, and is used clinically in treating senile constipation and postpartum constipation. The clinical symptoms are usually cold-heat deficiency-excess mixed, the above drugs have single drug effect, the sale amount is not considerable, and there is no systematic and detailed clinical examination data.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides the bowel-relaxing granules, which have the functions of invigorating spleen and replenishing qi, warming kidney and replenishing vital essence, and relaxing bowel; it is suitable for treating habitual constipation, constipation of the elderly, hemorrhoid constipation, puerperal constipation, and constipation after anorectal operation due to spleen qi deficiency, intestinal dryness and heat accumulation, body fluid deficiency, and kidney yang deficiency.
The purpose of the invention is realized by the following technical scheme:
the bowel-relaxing granule comprises the following components:
further, the intestinal tract dredging granules also comprise the following components:
sucrose dextrin.
Further, the weight parts of the components are as follows:
further, the weight parts of the components are as follows:
the invention has the beneficial effects that:
tongchun granule has effects of invigorating spleen and replenishing qi, warming kidney and replenishing vital essence, and loosening bowel to relieve constipation. It is suitable for treating habitual constipation, constipation of the elderly, hemorrhoid constipation, puerperal constipation, and constipation after anorectal operation due to spleen qi deficiency, intestinal dryness and heat accumulation, body fluid deficiency, and kidney yang deficiency.
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict.
The first embodiment is as follows:
the intestinal tract dredging granule comprises a component A and a component B,
the component A comprises the following components in parts by mass (in grams):
the component B comprises the following components in parts by mass (in grams):
sucrose 100 dextrin 650.
Mixing the components except for the pseudo-ginseng in the component A, and adding water to decoct for twice to obtain a decoction; filtering the decoction, concentrating under reduced pressure to obtain a clear paste with the relative density of 1.08-1.16 (80 ℃), crushing the pseudo-ginseng into pseudo-ginseng fine powder, adding the pseudo-ginseng fine powder and the component B into the clear paste, and granulating in one step to obtain the bowel-relaxing granules. 1000g of bowel-relaxing granules are prepared.
During decoction, 10 times of water is added for the first time of decoction, and the decoction is carried out for 1.5 hours; adding 8 times of water into the second decoction, and decocting for 1 hour.
Tongchun granule has effects of invigorating spleen and replenishing qi, warming kidney and replenishing vital essence, and loosening bowel to relieve constipation. Can be used for treating habitual constipation, senile constipation, hemorrhoid constipation, and constipation due to anorectal operation.
The taking method comprises the following steps: the medicine is taken with boiled water after meals, 15-30 g for one time, and three times a day.
The clinical manifestations of constipation are: (1) difficulty or effort in defecation, unsmooth defecation, reduced defecation frequency, and less dry and hard feces (2) with symptoms of abdominal distension, abdominal pain, dizziness, epigastric distress, belch, inappetence, insomnia, and vexation.
The theory of traditional Chinese medicine considers that the disease location of constipation is mainly in the large intestine and closely related to the viscera such as lung, spleen, stomach, liver, kidney, etc. The basic pathogenesis is the dysfunction of large intestine conduction, such as excessive stomach heat, fluid consumption and loss of moistening of the intestine; spleen-lung qi deficiency can lead to weak conduction in the large intestine; stagnation of liver qi, stagnation of qi, or transformation of qi into fire damaging fluids, and obstruction of fu-organs; when kidney yin is deficient, the intestinal tract is disordered, while kidney yang is deficient, the yin-cold is stagnated and the body fluids are obstructed. Therefore, it can affect the conduction of large intestine and cause this disease. The theory of traditional Chinese medicine advocates that the treatment of the disease is based on the principle of clearing the lower energizer, the excess syndrome is mainly eliminating the pathogenic factors, and the deficiency syndrome is firstly strengthening the body resistance, so as to treat both the symptoms and root causes. Just as in Jingyue quan Shu, miscellaneous syndrome plan, secret knot cloud: for yang nodes, excess pathogen should be removed; for deficiency of yin-accumulation, nourishing herbs should be used "
The formula of the bowel relaxing granule is combined with the two prescriptions and clinical application experience of the ancient prescription, namely, Maziren pill, Jichun Jian, wherein the prescription uses the Maziren, the officinal magnolia bark, the immature bitter orange, the Chinese goldthread, the sophora flower, the paris polyphylla, the tree peony bark and the honey-fried licorice root which are originally recorded in the Maziren pill to moisten intestines and purge heat, and expel pathogenic factors of qi and break knots. Radix astragali, radix Codonopsis, Atractylodis rhizoma, radix rehmanniae and semen Pruni can be added into Cistanchis herba from JICHUAN decoction to invigorate qi, invigorate spleen, enrich blood, promote fluid production, warm and tonify kidney yang, moisten intestine and relieve constipation. A small amount of Notoginseng radix is added for replenishing blood and regulating blood. The whole formula embodies the traditional Chinese medicine treatment method of tonifying qi and spleen, warming and invigorating kidney yang, nourishing yin and replenishing vital essence, and relaxing bowel and the idea of the traditional Chinese medicine holism concept. Has the idea of combining strong diseases and symptoms and treating both principal and secondary aspects of diseases.
The formula of the bowel-relaxing granule is prepared from two prescriptions in ancient prescription, namely, Maziren pill, and Jichuan decoction, and clinical medication experience, wherein the prescriptions are prepared from the original Maziren, the officinal magnolia bark, the immature bitter orange, the wine coptis chinensis, the sophora flower, the paris polyphylla, the tree peony bark and the honey-fried licorice root in the Maziren pill, and the honey-fried licorice root is used for moistening intestines, purging heat, discharging qi and breaking knots. For cistanche deserticola in Jichuan decoction, radix astragali, radix Codonopsis, rhizoma Atractylodis Macrocephalae, radix rehmanniae and semen Pruni are added to tonify qi and spleen, enrich blood and promote fluid production, warm and tonify kidney yang, moisten intestines and relax bowels. A small amount of Notoginseng radix is added for replenishing blood and regulating blood. Radix astragali is sweet and warm, enters spleen and lung channels, and has the effects of invigorating spleen and replenishing qi; cistanchis herba is sweet and salty, warm and moist, enters kidney and large intestine, warms kidney and benefits essence, moistens dryness and smoothes intestine, is the essential medicine for constipation due to kidney deficiency, and the combination of the two medicines is the monarch medicine. Radix Codonopsis is sweet and neutral, and has effects of invigorating qi, nourishing blood, and promoting fluid production; the largehead atractylodes rhizome has the effects of tonifying qi and spleen, hilling and growing gold, and assisting the astragalus root to invigorate the spleen; fructus cannabis is sweet in taste and neutral in nature, moist in nature and rich in lipid, enters the large intestine of the spleen and the stomach, benefits yin of the spleen and the stomach and is especially capable of moistening the intestine and dredging the channel; the bunge cherry seed is neutral in nature, pungent, bitter and sweet in taste, has the functions of invigorating spleen, large intestine and small intestine channels, moistening dryness, slowly purging and relaxing bowels, and helps the desertliving cistanche to smooth intestines and relax bowels, and the various medicines are combined and are used as ministerial medicines together. Coptidis rhizoma, flos Sophorae Immaturus, rhizoma paridis, and cortex moutan with bitter and cold properties for purging heat and relaxing bowels; radix rehmanniae is sweet and cold, and has the effects of nourishing yin and promoting the production of body fluid; immature bitter orange for breaking knots, magnolia officinalis for removing fullness, and all the medicines for slightly reducing heat accumulation to remove gastrointestinal dryness-heat are used as adjuvant medicines together; prepared licorice root, radix Glycyrrhizae Praeparata coordinates the effects of the other drugs in the recipe, and acts as a guiding drug. The medicines are combined to play the roles of moistening and relaxing bowels. The whole formula embodies the traditional Chinese medicine treatment method of tonifying qi and spleen, warming and invigorating kidney yang, nourishing yin and replenishing vital essence, and relaxing bowel and the idea of the traditional Chinese medicine holism concept. Has the idea of combining strong diseases and symptoms and treating both principal and secondary aspects of diseases.
The theory of traditional Chinese medicine considers that the disease location of constipation is mainly in the large intestine and closely related to the viscera such as lung, spleen, stomach, liver, kidney, etc. The pathological nature can be summarized into cold, heat, deficiency and excess.
1. Heat accumulation in the intestines and stomach: excessive drinking, overeating with fat, sweet and thick taste, heat accumulation in the stomach and intestine, dryness of heat and body fluid, and malnutrition of the intestinal tract, manifested as abdominal fullness and distention, dry mouth, halitosis, red face, fever, restlessness, red and dry tongue, yellow and dry coating, and slippery and rapid pulse. In the formula, the Chinese medicinal wine, namely the coptis root, the sophora flower and the moutan bark are used for specially purging heat, and the radix rehmanniae is matched for purging heat without damaging yin. Hou Po Zhi enters the body to break the pathogenic accumulation and increase water to go through the boat.
2. Deficiency of both qi and blood: asthenia, qi deficiency leading to weakness of large intestine transmission, blood deficiency leading to fluid depletion and loss of moistening of intestine, manifested by dry stool, difficulty in defecation, debilitation, pale complexion, sweating, short breath, palpitation, dizziness, pale tongue with white coating, and thready pulse. In the formula, astragalus, codonopsis pilosula and bighead atractylodes rhizome benefit qi and invigorate the spleen, and pseudo-ginseng and honey-fried licorice root nourish blood and tonify qi, and harmonize the drugs in the recipe.
3. Constipation due to yang deficiency: yang deficiency may cause the intestinal tract to lose its warm-up and accumulation of yin-cold, resulting in weakness of stool, difficulty in stool, pale complexion, cold limbs, pale tongue with white or thin greasy coating, and deep and slow pulse. In the formula, the cistanche deserticola warms and tonifies kidney yang, and is matched with the honey-fried licorice root which nourishes blood and tonifies qi.
Modern medicine considers that: the causes of constipation are different, and the constipation is classified into organic constipation and functional constipation according to the existence of organic pathological changes, the organic constipation is mainly treated by aiming at the causes of the constipation, and the functional constipation needs medicines for regulating and changing living habits so as to achieve diagnosis and treatment effects. Habitual constipation, senile constipation, hemorrhoid constipation, difficult defecation after anorectal operation and other symptoms can be treated by the recipe.
In conclusion, the reasons for constipation can be deficiency or excess, and deficiency or excess can be mixed, the formula of the bowel-relaxing granule conforms to the theory of traditional Chinese medicine, and according to the treatment principle of tonifying qi and strengthening spleen, warming and invigorating kidney yang, nourishing yin and replenishing vital essence, and relaxing bowel, the effective medicine for treating constipation which is summarized clinically for a long time is collected from the cutting of Ji Chuan Jian in Ma ren Wan (Chinese character of decoction). Clinical verification shows that the medicine has the effects of invigorating qi and strengthening spleen, warming and invigorating kidney yang, nourishing yin and replenishing vital essence, and relaxing bowel for constipation of various symptoms. Has good curative effect on organic and functional constipation diagnosed by modern medical science and difficult defecation after anorectal operation.
The formula of the bowel-relaxing granule is suitable for habitual constipation, old people constipation, hemorrhoid constipation and postpartum constipation caused by spleen qi deficiency, intestinal dryness and heat accumulation, body fluid deficiency and kidney yang deficiency. In order to further meet the requirements of patients and facilitate the use of the patients, the prescription is prepared into granules through demonstration and experiments, and the granules are convenient for the patients to take and store.
The intestinal tract dredging granule has low cost, is safe and reliable, and has good response after being clinically used for 5 years.
The intestinal tract dredging granule has mild drug property, low price, no special contraindication and no side effect, and all patients who are subjected to drug administration are improved to different degrees, and the intestinal tract dredging granule has been used for 5 years.
The formula of the intestinal dredging granules is as follows from 2016-2020 use cases:
TABLE 1 use of bowel-relaxing granules 2016 year old
TABLE 2 usage of TONGCHANG granule in 2017 years
TABLE 3 usage of TONGCHANG granule in 2018 years
TABLE 4 usage of TONGCHANG granule in 2019 years
TABLE 5 usage of TONGCHANG granule 2020 years
Example two:
the bowel relaxing granule comprises the following components in parts by mass:
typical case one
The patient, woman, 75 years old, Wenchuan northern Qiang autonomous county, Sichuan province, has a doctor in 2019 for 8 and 22 days, mainly complains about difficulty in defecation with anal distending pain for 5 years, has no obvious reason before 5 years, defecates for 1 time/1 to 2 days, is dry, has the shape of sheep manure, is unsmooth in defecation, is weak in defecation and easy to sit, is plump and painful in anus after defecation, is pale in complexion, is not warm in limbs, is fond of heat and cold, is fatigued and weak, is slightly relieved after being subjected to self-made hemp seed pills, has recurrent after-symptoms, and gradually worsens the disease. Before 2 months, the symptoms of the patients are aggravated, and the patients are treated by oral medicines in local hospitals (the specific diagnosis and treatment are not detailed), but the effects are not good enough, and the disease conditions are not obviously relieved. The diagnosis in the future is usually clear, refreshing, good spirit, and general diet and sleep. The tongue is pale red, the coating is thin and white, and the pulse is deep and thready.
Special examination: the abdomen is flat, and varicose veins and gastrointestinal peristalsis waves are not seen; the abdomen was soft, the middle abdomen was tendering (-) and the lower abdomen was tendering (-) without any rebound pain and muscular tension, and no lump was touched. The lower costal aspect of the liver and spleen, Murphy's syndrome (-); no percussion pain in the kidney areas, abdominal mobility with dullness (-); no smell of the medicine can lead to the intestinal sounding being intensified, and no smell of the medicine can lead to the water-borne sound. The anus is centered, the appearance is not deformed, and the perianal is obviously raised with subcutaneous varicose veins. Finger diagnosis: the rectal mucosa is loose, the finger wrapping feeling is obvious, and blood stain is not seen in the finger stall. Visible under anoscope: the rectal mucosa is hemispherical and blocks the intestinal cavity, and a little mucus adheres to the surface of the mucosa.
Defecation radiography: hypertrophic spasm of anal sphincter
Traditional Chinese medicine diagnosis: constipation (deficient secret)
And (3) Western diagnosis: constipation
And (3) pathogenesis analysis: the elderly patients have deficiency of qi and blood, deficiency of yang-qi, inability to nourish the intestines, and inability of large intestine to transmit, which in turn causes difficulty in defecation and difficulty in defecation, resulting in obstruction of constipation, deficiency of qi failing to promote yang-qi and hypodynamia, deficiency of the body, deficiency of yang and internal cold, inability to warm body, and lack of appetite, so that the symptoms of poor complexion and wine container, cold limbs, preference for heat and cold, pale tongue with white coating, deep and thready pulse are the manifestations of spleen-kidney yang deficiency.
Therapeutic method: to invigorate spleen, replenish qi, warm kidney, replenish vital essence, moisten intestines and relax bowels.
The prescription is as follows: the intestinal tract-relaxing granule of the present example.
The use method comprises the following steps: one dose is taken every day, one dose is decocted with water 600ml, 200ml once, 1 day for 3 times, and warm taken after meals. Order the patient to take a combination of work and rest, light diet and proper exercise.
And (3) return diagnosis: in 2019, 29 months after 8, 6 doses above are taken, and patients are asked to continue taking the medicine for 1 month for further treatment because of the age and the family clinic of the patients, the defecation is 1-2 days/time after the patient complaints the medicine, the defecation laboursome condition is relieved, the stool quality is slightly soft, the patients still have weakness after the defecation and cold limbs.
Three diagnoses: in 2019, 10 and 2 days, patients complain of good spirit, vigorous activity, defecate for 1-2 days/time, loose stool, smooth defecation, obvious improvement of mental fatigue and weakness, conscious and mild limbs, and follow-up clinic. Patients complain about the good effect and require prescription notice and medication nearby. The subsequent call follow-up shows that the patient has regular stool and good mental state.
Typical case two
The patient, male, 65 years old, qiang nationality Qiang nationality of China Songpan county of the Asian nationality of the Ara dam, visited a doctor 11, 14 days in 2019, the patient was admitted with a hospital for 3 years because of defecation difficulty with anal pendant expansion, the patient had no obvious reason before 3 years, had dry stool, had struggled to lack of strength in the adjacent toilet, had difficulty in discharging, had weak after defecating, short breath after sweating, cold limbs, fond of warmth and fear of coldness, soreness and coldness of waist and knees, clear and long urine, occasionally had a pain of spasm and coldness in the abdomen, and the patient was slightly relieved after taking the medicine (folium sennae) by oneself, and had general sleep. A pale-red tongue with thin and white coating and a deep and thready pulse
Special examination: the abdomen is flat, and varicose veins and gastrointestinal peristalsis waves are not seen; the abdomen was soft, the middle abdomen was tendering (-) and the lower abdomen was tendering (-) without any rebound pain and muscular tension, and no lump was touched. The lower costal aspect of the liver and spleen, Murphy's syndrome (-); no percussion pain in the kidney areas, abdominal mobility with dullness (-); no smell of the medicine can lead to the intestinal sounding being intensified, and no smell of the medicine can lead to the water-borne sound.
Traditional Chinese medicine diagnosis: constipation (deficient secret)
And (3) Western diagnosis: constipation
And (3) pathogenesis analysis: for the elderly patients, spleen qi deficiency and yang qi deficiency can not nourish the intestines, large intestine transmission is weak, and then constipation and difficult defecation are caused, so that constipation is caused, qi deficiency can not promote yang qi, so that fatigue is caused, people feel struggling in toilet, yang deficiency and internal cold are caused, warm body is unavailable, and the face horn wine is not warm in limbs, likes hot and cold, and is clear and long in urine; the cold in the interior of the body is usually collected and induced, so there are occasionally pain and spasm in the abdomen; kidney yang deficiency, so it is manifested as soreness and cold of the loins and knees, pale tongue with white coating, deep and thready pulse, which are all due to spleen-kidney yang deficiency.
Therapeutic method: invigorating spleen and qi, warming kidney and replenishing vital essence, moistening intestine and relaxing bowels
The prescription is as follows: the intestinal tract-relaxing granule of the present example.
The use method comprises the following steps: one dose is taken every day, one dose is decocted with water 600ml, 200ml once, 1 day for 3 times, and warm taken after meals. Order the patient to take a combination of work and rest, light diet and proper exercise.
And (3) return diagnosis: in 2019, day 11 and day 28, the patient takes the above 7 preparations, takes out excrement for 1-2 days/time after taking the medicine, has smooth defecation, slightly soft excrement, weakness after defecation, cold limbs and clear and long urine, is still in cold waist and knees, does not have lower abdomen spasm and crymodynia during taking the medicine, and is required to continue taking the medicine for 1 month. Discomfort with advice
Three diagnoses: 30 months and 12 months in 2019, patients have complaints of good spirit, vigorous activity, 1-2 days/time of defecation, soft defecation, smooth defecation, obvious improvement of mental fatigue and weakness, mild subjective limb and good complaint effect, and require continuous medication to consolidate the curative effect. The local eating habits and climates of the patients are considered, the patients are advised to eat light food, drink more water, exercise in proper amount, follow-up visit by a post-call, and the patients have regular stool and good mental state.
Example three:
the intestinal tract dredging granule comprises a component A and a component B,
the component A comprises the following components in parts by mass (in grams):
the component B comprises the following components in parts by mass (in grams):
sucrose 20 dextrin 200.
Mixing the components except for the pseudo-ginseng in the component A, adding water, decocting twice to obtain a decoction, adding 10 times of water in the first decoction, and decocting for 1.5 hours; adding 8 times of water into the second decoction, and decocting for 1 hour; filtering the decoction, concentrating under reduced pressure to obtain a clear paste with the relative density of 1.08-1.16 (80 ℃), crushing the pseudo-ginseng into pseudo-ginseng fine powder, adding the pseudo-ginseng fine powder and the component B into the clear paste, and granulating in one step to obtain the compound.
Example four:
the intestinal tract dredging granule comprises a component A and a component B,
the component A comprises the following components in parts by mass (in grams):
the component B comprises the following components in parts by mass (in grams):
sucrose 200 dextrin 1000.
Mixing the components except for the pseudo-ginseng in the component A, adding water, decocting twice to obtain a decoction, adding 10 times of water in the first decoction, and decocting for 1.5 hours; adding 8 times of water into the second decoction, and decocting for 1 hour; filtering the decoction, concentrating under reduced pressure to obtain a clear paste with the relative density of 1.08-1.16 (80 ℃), crushing the pseudo-ginseng into pseudo-ginseng fine powder, adding the pseudo-ginseng fine powder and the component B into the clear paste, and granulating in one step to obtain the compound.
The above-mentioned embodiments only express the specific embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.
Claims (4)
2. the bowel relaxing granule of claim 1, wherein: the intestinal tract dredging granule also comprises the following components:
sucrose dextrin.
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Citations (2)
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CN1194151A (en) * | 1997-03-26 | 1998-09-30 | 蒲绍卿 | Traditional Chinese medicine changtongning for curing chronic constipation |
CN105641335A (en) * | 2016-03-25 | 2016-06-08 | 武美英 | Kidney tonifying, qi benefiting, intestine moistening and bowel relaxing decoction for treating senile constipation |
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2021
- 2021-10-26 CN CN202111249639.XA patent/CN113769008B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1194151A (en) * | 1997-03-26 | 1998-09-30 | 蒲绍卿 | Traditional Chinese medicine changtongning for curing chronic constipation |
CN105641335A (en) * | 2016-03-25 | 2016-06-08 | 武美英 | Kidney tonifying, qi benefiting, intestine moistening and bowel relaxing decoction for treating senile constipation |
Non-Patent Citations (2)
Title |
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晓园等: "润肠通腑颗粒治疗老年便秘临床观察", 《山西中医》 * |
王小平等: "益气健脾润肠汤治疗慢传输型便秘50例疗效观察--", 《云南中医中药杂志》 * |
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