CN101264141B - Chinese medicinal composition containing Chinese rhubarb and preparation thereof - Google Patents

Chinese medicinal composition containing Chinese rhubarb and preparation thereof Download PDF

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Publication number
CN101264141B
CN101264141B CN2007100380161A CN200710038016A CN101264141B CN 101264141 B CN101264141 B CN 101264141B CN 2007100380161 A CN2007100380161 A CN 2007100380161A CN 200710038016 A CN200710038016 A CN 200710038016A CN 101264141 B CN101264141 B CN 101264141B
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radix
chinese medicine
rhizoma rhei
processed
constipation
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CN101264141A (en
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王龙武
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JIAO FENGNA
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Abstract

The invention discloses a Chinese herbal medicine composition containing Chinese rhubarb and the preparation method, which is produced by raw material comprising Chinese rhubarb fried with honey, frying kaladana, sodium sulphate, figwort root and astragalus. The Chinese herbal medicine composition has the advantages of clearing heat and purging fire, removing stagnancy, moistening the intestines and promoting secretion and benefiting qi, treating symptoms such as gastrointestinal retentin, internal heat and vexation, dry feces and helvolus emiction and having better clinical value.

Description

A kind of treat constipation contain Chinese medicine composition of Radix Et Rhizoma Rhei and preparation method thereof
Technical field:
The present invention relates to technical field of Chinese medicines.Be specifically related to a kind of Chinese medicine composition that contains Radix Et Rhizoma Rhei and preparation method thereof.
Background technology:
Astriction is a constipation, excrement matter dry, hard, often separate and not well a kind of disease. be human modal a kind of acute disease, it is the root that causes multiple disease, serious prestige victimization class health. thereby use purgation usually in the treatment constipation, decrease its body fluid, so that temporary transient logical secret, but the later stage dryness accumulated in the stomach and intestine is more. thus not logical not answering, damage healthy energy.The Chinese herb rhubarb heat and toxic materials clearing away, clearing away heat-fire, removing blood stasis. the Semen Pharbitidis removing water retention by purgation, go to amass. to fry with alleviating its high property. two medicines are monarch, and the Matrii Sulfas Exsiccatus moistening for dryness and softening hard mass is a ministerial drug, the Radix Scrophulariae clearing away heat-fire, YIN nourishing. Radix Astragali spleen invigorating QI invigorating is an adjuvant. all medicines match and form a clearing away heat-fire, consumer product dredge stasis, intestine moistening is promoted the production of body fluid, the agent of QI invigorating.How they are made up, being used for the treatment of constipation is the problem of paying close attention to.
Summary of the invention:
Technical problem to be solved by this invention is the Chinese medicine preparation that a kind of gastrointestinal tract of research design is used.
The inventor has changed traditional therapy. capture heat clearing away, removing food stagnancy and do not decrease its body fluid improves the later stage dryness accumulated in the stomach and intestine, logical not should, the shortcoming of damage healthy energy.The research medication is convenient, curative effect reliable, have no side effect and economical and practical Chinese herb rhubarb preparation.
The invention provides a kind of Chinese medicine composition (intestine moistening open capsule) that contains Radix Et Rhizoma Rhei, the raw material of Chinese medicine of making this Chinese medicine composition is pressed column weight amount proportioning and is consisted of:
Make by following Chinese medicine raw materials by weight proportion: processed with honey Radix Et Rhizoma Rhei 50g-150g, stir-fry Semen Pharbitidis 50g-150g, Matrii Sulfas Exsiccatus 30g-48g, Radix Scrophulariae 30g-48g, Radix Astragali 30g-48g.
Radix Et Rhizoma Rhei heat and toxic materials clearing away in the side, clearing away heat-fire, removing blood stasis. the Semen Pharbitidis removing water retention by purgation, go to amass. to fry with alleviating its high property. two medicines are monarch, and the Matrii Sulfas Exsiccatus moistening for dryness and softening hard mass is a ministerial drug, the Radix Scrophulariae clearing away heat-fire, YIN nourishing. Radix Astragali spleen invigorating QI invigorating is an adjuvant. all medicines match and form a clearing away heat-fire, consumer product dredge stasis, intestine moistening is promoted the production of body fluid, the agent of QI invigorating.
Function: clearing away heat-fire, consumer product dredge stasis, intestine moistening is promoted the production of body fluid, QI invigorating.
Cure mainly: gastrointestinal retention, interior-heat is vexed, constipation due to dry stool, yellowish or reddish urine etc.
Usage and consumption: one time 2,3 times on the one, according to state of an illness adjustable dosage.
Specification: 0.5g/ grain
Attention: 1, anemia of pregnant woman and allergic constitution person forbidding.
2, the careful usefulness of body void person.
3, the child should take under physician guidance.
Forbid when 4, property of drug changes taking.
5, when taking other medicines, answer referring physician or pharmacist before use this product.
Another purpose of the present invention has provided the above-mentioned preparation method that contains the Chinese medicine composition (intestine moistening open capsule) of Radix Et Rhizoma Rhei, and this method comprises the following steps:
(1) raw material of Chinese medicine is concocted:
Radix Et Rhizoma Rhei processed with honey: earlier Mel is put in the pot, be heated to and boil, add rhubarb tablets, fry extremely tack-free be degree, every 500g rhubarb tablets Mel 90g with slow fire; The Semen Pharbitidis parching to brown: get clean Semen Pharbitidis and put in the pot, fry to little heaving with slow fire, take out; Radix Scrophulariae salt is processed: Radix Scrophulariae sheet and saline are mixed thoroughly, be heated to saline to the greatest extent the time, put the pot little stir-fry of interior slow fire, taking-up cools, and every 500g Radix Scrophulariae is used Sal 15g, and water is an amount of, dissolves to clarify; The Radix Astragali is given birth to and is used; Matrii Sulfas Exsiccatus is a finished product;
(2) manufactured goods
Accurately take by weighing the spice of the above-mentioned process of preparing Chinese medicine: the processed with honey Radix Et Rhizoma Rhei, fry Semen Pharbitidis, salt is processed Radix Scrophulariae, and the Radix Astragali and Matrii Sulfas Exsiccatus are ground into fine powder, and be promptly encapsulated after sterilizing. every 0.5g.
Above-mentioned fine powder is 100 orders.
The Radix Et Rhizoma Rhei Chinese medicine composition that contains of the present invention is through for many years clinical practice, and effect is better than similar Western medicine, does not find any toxic and side effects.Be difficult for to produce drug resistance, to the function of human body immune system without any stimulation.Than Chinese medicine decoction taking convenience, curative effect is reliable, and side effect is little, and the patient is acceptant, is worth of widely use, and allows extensive patients obtain the effective treatment, and clinical value is preferably arranged.
The specific embodiment:
(1) Chinese medicine composition of the present invention (intestine moistening open capsule) clinical practice
Example 1, Zhao xx man people from Boai County of 61 years old Henan Province
The patient has chronic bronchitis, hypertension 10 years surplus.Constipation, companion's abdominal distention 4 years increased the weight of 4 days, anorexia, the food back is glutted.Certain hospital diagnosis habitual constipation.Once obeyed phenolphthalein tablet, and then rushed down after taking with Chinese medicine Folium Sennae tea of an amount of soaked generation etc., drug withdrawal as before, my the institute's diagnosis and treatment of coming.Recently chronic bronchitis morbidity, infusion treatment recovery from illness on the 7th.The food of receiving after four days is tasteless, distension and fullness in the abdomen, and constipation with dry stool, energy is tired out, yellowish complexion, red tongue, the heel teeth trace, thin fur is owed Tianjin, thready and rolling pulse.
Dialectical: weakness of the spleen and stomach, the disease of body fluid deficiency.
Therapeutic Method: replenishing QI to invigorate the spleen, intestine moistening is promoted the production of body fluid.
Medication; Intestine moistening open capsule 0.5g, one time 2,3 times on the one, serve on 7.
Two examine: distention and fullness in the abdomen, and constipation with dry stool, energy improvement tired out advises it with obeying 30, follows up a case by regular visits to its symptom and disappears substantially, accuses more.
Example 2,28 years old people from Boai County of peasant Henan Province of section xx woman
Private prosecution feels depressed over 5 years puerperal, the gastral cavilty distension, and constipation, the decreased food intake of receiving is few, and menstrual cycle has clot in advance, and amount is many.Defecate 4~7 in recent months once.Take traditional Chinese medicine in certain hospital, Western medicine is not quite clear, but after the drug withdrawal as before.My the institute's diagnosis and treatment of coming.Examine and see that patient's body is little fat, the little reddish yellow of bread, greasy and thin fur, stringy pulse.
Dialectical: the gastral cavilty distension, constipation, the decreased food intake of receiving is few, and the pent-up of feelings will is caused by stagnation of QI in spleen and stomach, depression and stagnation of QI, the conduction dereliction of duty, so the gastral cavilty distension, constipation is levying of hindering in the stagnation of QI.
Therapeutic Method: pleasant intestinal stasis relieving, the intestine moistening of promoting the production of body fluid.
Medication: intestine moistening open capsule 0.5g, one time 2,3 times on the one, serve on 15 and heal.
Example 3,65 years old people from Boai County of peasant Henan Province of king xx man
On October 16th, 2002, readme is constipation with dry stool over 16 years, and distension and fullness in the abdomen is for a long time by clothes Radix Et Rhizoma Rhei SB sheet, phenolphthalein tablet.But delegation on the 5th~7 after the drug withdrawal, dyschezia.Come my institute's diagnosis and treatment.Examine and see the patient, red complexion, xerostomia, red tongue, the few Tianjin of white and thin fur, slippery and rapid pulse.
Card belongs to: knot in damp and hot, body fluid deficiency liquid is dry.
Therapeutic Method: clear interior-heat, the intestine moistening of promoting the production of body fluid.
Medication: intestine moistening open capsule 0.5g, one time 2,3 times on the one, serve on 7.
Two examine: constipation with dry stool, distension and fullness in the abdomen takes a turn for the better.Advise it to take again 30, follow up a case by regular visits to its all disease and recover recovery from illness substantially.
Example 4,54 years old people from Boai County of workman Henan Province of xx man
First visit on June 18 in 1999.The readme stool was not separated on the 6th, and heating installation is done frequently, and the feeling of stuffiness in chest is full, and diet reduces, and stool must not be separated, distension pain in the abdomen, yellow fur, rolling pulse string.This patient once had the cerebral embolism disease and healed.
Dialectical: the pent-up of feelings will, stagnation of QI in spleen and stomach is so belch is done frequently.The feeling of stuffiness in chest is full.Depression and stagnation of QI, the conduction dereliction of duty stops in the waste matter, so constipation.Yellow fur, rolling pulse string, interior intenseness of heat.Card belongs to: the damp and hot stagnation of QI, intestine moistening is promoted the production of body fluid.
Medication: intestine moistening open capsule 0.5g, one time 4,3 times on the one, serve on 7 and heal.
Example 5,48 years old people from Mengzhou City of teacher Henan Province of king xx woman
First visit on November 12 in 1998.Readme constipation 5 years was then sent out to winter, headache, and lower abdominal pain, lack of appetite is indigestion and loss of appetite, hands and feet coolness, frequent micturition is long clearly, aversion to cold, light red tongue is white, deep-slow pulse.This is a deficiency of YANG QI, can not transmit intestinal, waste matter and cause difficulty in defecation, the large intestine drying of holding concurrently again, deficiency of body fluid, in stop with the passing of time, and cause constipation.
Therapeutic Method: the intestine moistening of promoting the production of body fluid.
Medication: intestine moistening open capsule 0.5g, one time 2,3 times on the one, serve on 7, Rhizoma Zingiberis Recens soup takes.
Two examine: all diseases in back of taking medicine are taken a turn for the better, and advise and obey 60 again.Following up a case by regular visits to its disease is almost recovered.
Example 6,50 years old people from Wen County of peasant Henan Province of Lee xx woman
Calendar year 2001 first visit on April 8.About private prosecution constipation 8 years.Often take phenolphthalein tablet, Radix Et Rhizoma Rhei SB sheet, stop then as before.Card is seen constipation, and it is unfavorable to defecate, breast side of body feeling of fullness, and abdominal distention, the decreased food intake of receiving is few, greasy and thin fur, stringy pulse.
Dialectical: the pent-up of feelings will, the liver losing its smoothly moving state, stagnation of QI in spleen and stomach, thus breast side of body feeling of fullness, depression and stagnation of QI, conduction dereliction of duty.Stop in the waste matter, then big informal letter is obstructed.Greasy and thin fur, stringy pulse is levying of hindering in the stagnation of QI.
Therapeutic Method: consumer product dredge stasis, intestine moistening is promoted the production of body fluid.
Medication: intestine moistening open capsule 0.5g, one time 4,3 times on the one, serve on 7.
Two examine: further consultation on April 16, and breast side of body feeling of fullness is defecated once-a-day, and all diseases subtract greatly, advise it to obey 30 again, follow up a case by regular visits to its disease and are almost recovered.
Example 7, xx woman people from Boai County of 46 years old Henan Province
First visit on August 16 in 1999.Nearly about 10 years of private prosecution constipation.Often buy rhubarb soda tablet by oneself and take, but can not drug withdrawal.My the institute's diagnosis and treatment of coming.Card is seen: lustreless complexion, and Mental fatigue is breathed hard, and defecation is not well, pale tongue, thin fur, deficient pulse.
Dialectical: asthenia of pulmonosplenic qi then face is not magnificent, and Mental fatigue is breathed hard.Because of the lung and the large intestine being interior-exteriorly related, failure of the lung to distribute body fluid to all parts of the body, large intestine transmits unable then dyschezia.Pale tongue, thin fur, deficient pulse are levying of the deficiency of vital energy.
Therapeutic Method: QI invigorating intestine moistening.
Medication: intestine moistening open capsule 0.5g, one time 2,3 times on the one, Ziziphi Jujubae Decoction takes, and serve on 7.
Two examine: August 24, Mental fatigue is breathed hard, the not well improvement of defecation.Advise it to obey 30, Ziziphi Jujubae Decoction is for drawing again.Follow up a case by regular visits to its disease and be almost recovered, advise its life to take good care of and take Ziziphi Jujubae Decoction for a long time.
Example 8, xx woman people from Boai County of 28 years old Henan Province
First visit on June 22 in 2003.Private prosecution constipation in 3 years puerperal.Open the clothes aloe capsule in certain hospital, behind the phenol peptide sheet, symptom takes a turn for the better, but after the drug withdrawal as before.Card meeting light yellow complexion, cardiopalmus, dizziness, constipation, once, menstrual blood volume is few about 5 days.Thin white fur of tongue, deep-thready pulse.
Dialectical: blood deficiency Tianjin is few, can not the relaxing the bowels with lubricant drugs large intestine, so constipation.Blood deficiency can not go up the Rong Ze lustreless complexion.Blood failing to tonify the heart is cardiopalmus then.Blood deficiency can not be nourished in brain then dizzy.Insufficiency of blood then menstrual blood volume is few, and thin white fur of tongue, deep-thready pulse belong to resembling of blood deficiency.
Therapeutic Method: benefiting QI and nourishing blood, intestine moistening are promoted the production of body fluid.
Medication: intestine moistening open capsule 0.5g, one time 3,3 times on the one, serve on 7.
Two examine: June 29, the back cardiopalmus of taking medicine, nervous, constipation improvement advise it to take 15 again.
Three examine: July 16, its disease subtracts greatly, and menstrual blood volume also increases to some extent, advises its decrement, one time 2,2 times on the one, obeyed again 30.Follow up a case by regular visits to its sick announcement more after 6 months.
Example 9,27 years old people from Boai County of peasant Henan Province of xx man
Calendar year 2001 first visit on May 16.Private prosecution was not defecated on the 5th.Cause heating on the 16th, headache, cough recover normal after treating, do not separate from modern stool.Card is seen: red complexion, and bitter taste, uncomfortable in chest, oliguria with reddish urine.Dry, rough and yellow fur, deep-rolling pulse.
Dialectical: accumulated heat in gastrointestinal tract, so consumption impairment of body fluid liquid is constipation.Interior-heat is fumigated in last, and then bitter taste is uncomfortable in chest.Heat is moved bladder, then oliguria with reddish urine.Dry and yellowish fur is an interior-heat impairment of body fluid, and forceful pulse is sliding, is levying of interior-excess.
Therapeutic Method: clearing away heat-fire, loosening bowel to relieve constipation.
Medication: intestine moistening open capsule 0.5g, one time 4,3 times on the one, serve on 3 days and accuse more.
Example 10,22 years old people from Boai County of peasant Henan Province of Xu xx woman
First visit on October 18 in 2003.The frequent constipation of private prosecution 3 years is surplus.Left in ear flows out yellow liquid, otalgia before 18 days.Be diagnosed as otitis media through this village clinic.The recovery from illness of transfusion back.Card is seen: flushed face and fever, bitter taste frowziness, abdominal distention.Be hard and dry.About 4 days once.Yellow fur, rolling and forceful pulse.
Dialectical: accumulated heat in gastrointestinal tract, so consumption impairment of body fluid liquid is constipation.The stifling then bitter taste of interior-heat, halitosis, flushed face and fever.Yellow fur is a heat impairment of body fluid, and rolling and forceful pulse is levying of interior-excess.
Therapeutic Method: clearing away heat-fire, loosening bowel to relieve constipation.
Medication: intestine moistening open capsule 0.5g, one time 4,3 times on the one, serve on three days and accuse more
Example 11,70 years old people from Boai County of peasant Henan Province of Lee xx man
First visit on October 26 in 1999.About private prosecution constipation 16 years, the informal dress phenolphthalein tablet, Radix Et Rhizoma Rhei SB is for many years.Card is seen: difficulty in defecation, discharge difficulty, and urine is many, and complexion is little white, and happiness heat is disliked cold, the abdomen cold type of pain, pale tongue, tongue is white, deep-slow pulse.
Dialectical: aged debility, intestinal imbalance, deficient and weak YANG QI in addition, intestinal transmits unable, and then difficulty in defecation is yin-cold excess, functional activity of QI being not smooth, abdomen cold type of pain then, happiness heat is afraid of cold.Insufficiency of kidney-YANG, deficiency-cold in the urinary bladder, then just long clearly, complexion is little white, pale tongue, tongue is white, and deep-slow pulse is levying of yang deficiency endogenous cold.
Therapeutic Method: warming YANG gas, loosening bowel to relieve constipation.
Medication: intestine moistening open capsule 0.5g, one time 2,3 times on the one, Rhizoma Zingiberis soup takes, and serve on 7.
Two examine: November 5, and difficulty in defecation, urine is many, and happiness heat is disliked cold, the improvement of taking a favourable turn of abdomen cold type of pain, intestine moistening open capsule 0.5g took 15 again, and Rhizoma Zingiberis soup takes.
Three examine: November 21, all symptoms are almost recovered, and advise its continuation to take 30 again.Follow up a case by regular visits to after 6 months and accuse more.
Example 12,66 years old people from Boai County of peasant Henan Province of Zhao xx man
First visit on November 18 in 2000.Defecate and do not separate in 6 days, belch is done frequently, and the feeling of stuffiness in chest is full, and diet is few, just must not desire distending pain in the abdomen, yellow fur, stringy pulse.The patient cerebral thrombosis disease is arranged, it is surplus just to have recovered February.Card belongs to pathogenic heat and dislikes due to the interior knot.
Therapeutic Method: relieve inflammation or internal heat and purge heat, loosening bowel to relieve constipation.
Medication: intestine moistening open capsule 0.5g, one time 4,3 times on the one, serve on 7.Follow up a case by regular visits to and accuse more.
(2) formulation preparation of the present composition (intestine moistening open capsule):
Example 13
Prescription
Processed with honey Radix Et Rhizoma Rhei 50g, stir-fry Semen Pharbitidis 50g, Matrii Sulfas Exsiccatus 30g, Radix Scrophulariae 30g, Radix Astragali 30g
Method
(1) raw material of Chinese medicine is concocted:
Radix Et Rhizoma Rhei processed with honey: earlier Mel is put in the pot, be heated to and boil, add rhubarb tablets, fry extremely tack-free be degree, every 500g rhubarb tablets Mel 90g with slow fire; The Semen Pharbitidis parching to brown: get clean Semen Pharbitidis and put in the pot, fry to little heaving with slow fire, take out; Radix Scrophulariae salt is processed: Radix Scrophulariae sheet and saline are mixed thoroughly, be heated to saline to the greatest extent the time, put the pot little stir-fry of interior slow fire, taking-up cools, and every 500g Radix Scrophulariae is used Sal 15g, and water is an amount of, dissolves to clarify; The Radix Astragali is given birth to and is used; Matrii Sulfas Exsiccatus is a finished product;
(2) manufactured goods
Accurately take by weighing the spice of the above-mentioned process of preparing Chinese medicine: the processed with honey Radix Et Rhizoma Rhei, fry Semen Pharbitidis, salt is processed Radix Scrophulariae, and the Radix Astragali and Matrii Sulfas Exsiccatus are ground into fine powder, and be promptly encapsulated after sterilizing. every 0.5g.
Example 14
Prescription
Processed with honey Radix Et Rhizoma Rhei 150g, stir-fry Semen Pharbitidis 150g, Matrii Sulfas Exsiccatus 48g, Radix Scrophulariae 48g, Radix Astragali 48g
Method is with example 13.
Example 15
Prescription
Processed with honey Radix Et Rhizoma Rhei 100g, stir-fry Semen Pharbitidis 100g, Matrii Sulfas Exsiccatus 40g, Radix Scrophulariae 40g, Radix Astragali 40g
Method is with example 13.

Claims (2)

1. Chinese medicine composition that contains Radix Et Rhizoma Rhei for the treatment of constipation, the raw material of Chinese medicine that it is characterized in that making this Chinese medicine composition is pressed column weight amount proportioning and is consisted of:
Processed with honey Radix Et Rhizoma Rhei 50g-150g, Semen Pharbitidis (parched) 50g-150g, Matrii Sulfas Exsiccatus 30g-48g,
Radix Scrophulariae 30g-48g, Radix Astragali 30g-48g.
2. a preparation method that contains the Chinese medicine composition of Radix Et Rhizoma Rhei as claimed in claim 1 is characterized in that this method comprises the following steps:
(1) raw material of Chinese medicine is concocted
Radix Et Rhizoma Rhei processed with honey: earlier Mel is put in the pot, be heated to and boil, add rhubarb tablets, fry extremely tack-free be degree, every 500g rhubarb tablets Mel 90g with slow fire; The Semen Pharbitidis parching to brown: get clean Semen Pharbitidis and put in the pot, fry to little heaving with slow fire, take out; Radix Scrophulariae salt is processed: Radix Scrophulariae sheet and saline are mixed thoroughly, be heated to saline to the greatest extent the time, put the pot little stir-fry of interior slow fire, taking-up cools, and every 500g Radix Scrophulariae is used Sal 15g, and water is an amount of, dissolves to clarify; The Radix Astragali is given birth to and is used; Matrii Sulfas Exsiccatus is former finished product;
(2) make capsule
Get the spice of the above-mentioned process of preparing Chinese medicine: the processed with honey Radix Et Rhizoma Rhei, Semen Pharbitidis (parched), salt is processed Radix Scrophulariae, and the Radix Astragali and Matrii Sulfas Exsiccatus are ground into fine powder, and be promptly encapsulated after sterilizing, every 0.5g.
CN2007100380161A 2007-03-13 2007-03-13 Chinese medicinal composition containing Chinese rhubarb and preparation thereof Expired - Fee Related CN101264141B (en)

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CN101264141B true CN101264141B (en) 2010-09-15

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Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
王霞.仝小林临证辨治肠梗阻经验.中国社区医师.2003,19(6),35. *
许山鹰.便秘的中医药疗法.中国临床医生.2001,29(8),10. *
黄艳.中医药治疗便秘的近况.辽宁中医学院学报.2005,7(1),23-24. *

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