CN103446573B - A kind of medicine for the treatment of of allergic rhinitis - Google Patents

Abstract

The invention belongs to the field of Chinese medicines, particularly a kind of medicine for the treatment of of allergic rhinitis.Be made up of the raw material of following weight parts proportioning: Radix Ginseng 30-80 parts, 50-100 parts, Poria, the Rhizoma Atractylodis Macrocephalae 50-100 parts, Rhizoma Zingiberis 30-80 parts, Radix Aconiti Lateralis Preparata 15-30 parts, fry 30-80 parts, Fructus Foeniculi, cervus elaphus linnaeus 10-30 parts, Fructus Lycii 30-100 parts, 20-60 parts, Radix Rehmanniae Preparata, Rhizoma Cibotii 20-60 parts, Herba Centipedae 30-90 parts, Fructus Amomi 15-30 parts, Cortex Cinnamomi 15-30 parts, Herba Epimedii 20-50 parts, Herba Asari 15-30 parts, Fructus Psoraleae 30-100 parts, 10-30 parts, Herba Ephedrae, Rhizoma Et Radix Notopterygii 15-30 parts, Concha Meretricis seu Cyclinae 30-60 parts, 15-20 parts, Radix Glycyrrhizae.The present invention asks the object because of, treating both the principal and secondary aspects of a disease in line with curing the disease, by Overall View and the dialectical thought treated, fundamentally solve the origin cause of formation of allergic rhinitis, thus reaches the object of thoroughly curing.Compatibility of the present invention is rigorous, and dialectical legislation side medicine is proper suits the medicine to the illness, and have no side effect, cure rate is high, makes patient's livelihood restoration normal after healing.

Description

A kind of medicine for the treatment of of allergic rhinitis

Technical field

The invention belongs to the field of Chinese medicines, particularly a kind of medicine for the treatment of of allergic rhinitis.

Technical background

Allergic rhinitis is the reaction of a kind of nonspecific inflammation, and doctor trained in Western medicine thinks that immune function of human body does not cause nasal mucosa to the responsing reaction of the external irritant such as cold air, pollen entirely or lowly.Long-term and excessive stimulation make answering lose and irritated, nasal decongestion, edema, hypertrophy and ventilation not smooth, force function too drastic (sneeze frequently do) or unwise (loss of smelling sense is good and foul smells) and some clinical responses of showing, as headache, snoring, nasal conchae hypertrophy, deviation of nasal septum, adenoids, hypopnea, antibacterial, viral infection etc.

The applicant thinks that primary disease belongs to the category of traditional Chinese medical science nasal sinusitis.Due to long-term eating cold and uncooked food excessively, cold material, lot of beer, its cold-damp is stranded caused by air resister, and the discrepancy of mechanism of qi relies on the gasification of yang-energy to the moon entirely, through speech " gathering of disease, its gas must be empty " thus.Sun take fire as this at body, with gas for.In human body, gas, vigour, qi of zang-fu viscera all result from sun heat, obtain allergic rhinitis it, must endogenous cold more very, and with upper, middle and lower three Jiao for wanting, mainly received too much cold and cool, as ice-cold, medicated beer, different time strange land fruit and vegerable and to blow air-conditioning, fan etc. too much.Run counter to the reason of nature, ancients say that side's water and soil supports a side people, and five li of different speeches, Ten li apart, but the customs are quite different.Traditional Chinese medical science Overall View and harmony between man and nature thought inform us, and " life, length, change, receipts, Tibetan " refers to nature and the positive discrepancy relation to the moon of human body.Summer is hot, People of the same tastes and habits like to be together, QI and blood is dispelled the heat at table, and human body planted agent is as the border Ying Liang of well, and now nature does not have ice, artificial and make and eat, it not to know in human body 36 DEG C, and ice is at subzero 4 DEG C, the temperature difference is at 40 DEG C, and a large amount of and life-time service, makes the sun of our middle-jiao yang, function of the spleen and stomach and the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels impaired in a large number.The machine of educating in the change in summer is unevident, has run counter to wanting of the nature of " summer will establish the yang function " at all.Summer is hot, and from-inner-to-outer mechanism of qi is fluent, and heat radiation is the fastest, for figure is fast for the moment, make outward air-conditioning, in drink cold drink, cold-evil is directly entered in it, and wound be positive, the sun of disorder of the spleen and stomach caused by internal damage, vessels of the uterus.Inside and outside trembling with fear makes the lifting of body negative and positive unbalance.The cold duty of taste in vessels of the uterus, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels cold coagulation, vessels of the uterus loses supports, and saps one's vitality, and makes to appoint cloudy incompetent, superintends and directs mistake replenishing vital QI with drugs of warm nature, decline of the fire from the gate of life, qiactivity of triple energizer mistake department (gate of vitality person three Jiao does not make yet), superintend and direct positive depressed, pass just in nose person, institute's mistake of superintending and directing.The resisting cold function of nose, entirely by superintending and directing the power of sun (fire from the gater of life), due to above reason, force people's coldness in the body condense, appoint fall unable.The sun of taste trembled with fear be stranded, stool conduction mistake department constipation (constipation due to cold pathogen).Stomach is through arising from nasal vestibule (inside and outside fragrant cave), and the urinary bladder channel frame nasion and play (Jingming acupoint), superintends and directs away in nose, establish for the gas of replenishing vital QI with drugs of warm nature suction.Therefore head is the remittance of all sun, clear sun is the use of upper orifices, and one is cold and cool now, the large wound of yang-energy, and Zhu Yang is impaired, qi-movement disturbance, and sun is red and swollen by cold tired then nose, cloudy by cold coagulation then nasal conchae hypertrophy.It will be argued that sun meets to tremble with fear then to spray, cloudy chance is cold then sneezes, and sneeze is work frequently.Stomach is received impaired, conduction mistake department, and stomachache, dysmenorrhea, impotence, dizziness, brain rise etc., and all are superintended and directed stranded disease and take place frequently.

Summary of the invention

The object of the present invention is to provide a kind of medicine for the treatment of of allergic rhinitis.

A medicine for treatment of allergic rhinitis, is characterized in that being made up of the raw material of following weight parts proportioning:

Radix Ginseng 30-80 parts, 50-100 parts, Poria, the Rhizoma Atractylodis Macrocephalae 50-100 parts, Rhizoma Zingiberis 30-80 parts, Radix Aconiti Lateralis Preparata 15-30 parts, fry 30-80 parts, Fructus Foeniculi, cervus elaphus linnaeus 10-30 parts, Fructus Lycii 30-100 parts, 20-60 parts, Radix Rehmanniae Preparata, Rhizoma Cibotii 20-60 parts, Herba Centipedae 30-90 parts, Fructus Amomi 15-30 parts, Cortex Cinnamomi 15-30 parts, Herba Epimedii 20-50 parts, Herba Asari 15-30 parts, Fructus Psoraleae 30-100 parts, 10-30 parts, Herba Ephedrae, Rhizoma Et Radix Notopterygii 15-30 parts, Concha Meretricis seu Cyclinae 30-60 parts, 15-20 parts, Radix Glycyrrhizae.

Its optimum ratio is made up of the raw material of following weight parts proportioning:

Radix Ginseng 50 parts, 50 parts, Poria, the Rhizoma Atractylodis Macrocephalae 50 parts, Rhizoma Zingiberis 50 parts, Radix Aconiti Lateralis Preparata 20 parts, stir-fry 50 parts, Fructus Foeniculi, cervus elaphus linnaeus 15 parts, Fructus Lycii 50 parts, 40 parts, Radix Rehmanniae Preparata, Rhizoma Cibotii 30 parts, Herba Centipedae 60 parts, Fructus Amomi 20 parts, Herba Epimedii 30 parts, Cortex Cinnamomi 20 parts, Herba Asari 15 parts, Fructus Psoraleae 50 parts, 15 parts, Herba Ephedrae, Rhizoma Et Radix Notopterygii 20 parts, Concha Meretricis seu Cyclinae 30 parts, 15 parts, Radix Glycyrrhizae.

Chinese medicine composition of the present invention conventionally can make the dosage forms such as ball, loose, water.Treatment water preparation method be that the clear water adding 4-5 times, above-mentioned Chinese medicine soaks more than 1 hour, decoct about 30 minutes, dry in the air cool rear filtration plastic bag sealing, sterilizing, packaging, every agent 3 bags, every bag of 250ml, ante cibum (medicine) being taken before meal, every day 3 times.As do ball powder type Chinese medicine composition can be pulverized respectively rear mixing thousand mesh sieves sieved after, with Mel with become honeyed pill, the heavy 6-9g of every ball, each 1 ball, every day 3 times.If do capsule formulation can load large size capsule (every is 1.0g), each serving large size capsule 10-15 grain, every day 3 times.Take period: serveing on January is a cycle, and three to May is a course for the treatment of.To take medicine taboo: to avoid eating anything raw or cold, seafood, bean curd, medicated beer, different time strange land fruit and vegerable and blow air-conditioning, fan.

The application ask in line with curing the disease because of, treating both the principal and secondary aspects of a disease, the dialectical object treated, with warming YANG to expel cold, expectorant fall appoint, tonifying vital QI, replenishing vital QI with drugs of warm nature fire from the gater of life, hold up superintend and direct, the object of dredging DU Meridian resisting cold, make to appoint and superintend and direct a small circle of the evolutive circulation and obtain recovery, achieve satisfied curative effect clinically.Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Fructus Amomi are monarch drug, build and protect taste; Rhizoma Zingiberis, Radix Aconiti Lateralis Preparata, stir-fry Fructus Foeniculi, Cortex Cinnamomi, Herba Epimedii, cervus elaphus linnaeus, Fructus Psoraleae are ministerial drug, warming spleen and stomach for dispelling cold, mend fire from the gater of life; Fructus Lycii, Radix Rehmanniae Preparata are the moon of adjuvant drug, nourishing the liver and kidney, help positive medicine and capable its is weighed; Herba Ephedrae, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Asari, Herba Centipedae, Concha Meretricis seu Cyclinae, Radix Glycyrrhizae for making medicine, removing dampness by means of aromatics, lung qi dispersing consolidating superficial resistance, sending down the abnormal ascending QI expectorant and logical appointing, coordinating the actions of various ingredients in a prescription.

Toxicity test of the present invention: this prescription has no obvious toxic and side effects in clinical practice.Untoward reaction is not found through routine patient up to a hundred.

Clinical experiment

One, clinical research data:

Selected case 100 example is 2002 to 2013 allergic rhinitises at the above hospital diagnosis of this city city-level, the age 3-15 year 30 examples, 16-70 year 70 examples, wherein women 48 example, course of disease 1-3 42 example, 3-10 34 example, more than 10 years 24 are routine.

Two, diagnostic criteria:

Clinical cold air stimulate or sooner or later sneeze take place frequently, have a headache, adenoids, nasal polyp, nasal vestibule edema and drying, nasal conchae hypertrophy, insomnia, snoring and tremble with fear as diagnostic criteria with gastrointestinal upset, dysmenorrhea, constipation, the back of the body.

Three, clinical scale:

Gently, divide three grades (mainly with painful area classification) in, heavily

Slight: sooner or later sneeze take place frequently, rhinocnesmus taking place frequently with headache, insomnia, flu.

Moderate: have mild and adenoids, nasal polyp, nasal vestibule edema and drying, nasal conchae hypertrophy, insomnia, snoring and with gastrointestinal upset, dysmenorrhea, constipation and watery stool.

Severe: have light, moderate symptoms, and with infertile, sexual impotence, premature ejaculation, back the disease such as cold and cool or pain.

Four, Therapeutic Method:

Every day three times, each serving large size capsule 10-15 grain (every is 1.0g), serveing on January is a cycle, and three to May is a course for the treatment of.

Five, clinical efficacy:

Gently, moderate symptoms all disappears, and follows up a case by regular visits to and do not recur for 1 year, is clinical cure.After treatment, light moderate symptoms makes moderate progress as taking a turn for the better.

1. cure: clinical symptoms is improved, and life can take care of oneself, 2 years again without repeatedly;

2. effective: control of taking medicine, within more than 1 year, do not recur;

3. effective: symptom alleviates;

4. invalid: symptom is without obvious change.

Six, therapeutic outcome:

In order to three courses for the treatment of of upper Regimen Chemotherapy, treatment 100 example, cure rate 87%, effective percentage 100%.

Detailed description of the invention

Embodiment 1

Side's medicine: Radix Ginseng 30g, Poria 50g, Rhizoma Atractylodis Macrocephalae 50g, Rhizoma Zingiberis 30g, Radix Aconiti Lateralis Preparata 15g, stir-fry Fructus Foeniculi 30g, cervus elaphus linnaeus 10g, Fructus Lycii 30g, Radix Rehmanniae Preparata 20g, Rhizoma Cibotii 20g, Herba Centipedae 30g, Fructus Amomi 15g, Cortex Cinnamomi 15g, Herba Epimedii 20g, Herba Asari 15g, Fructus Psoraleae 30g, Herba Ephedrae 10g, Rhizoma Et Radix Notopterygii 15g, Concha Meretricis seu Cyclinae 30g, Radix Glycyrrhizae 15g.

Embodiment 2

Side's medicine: Radix Ginseng 50g, Poria 50g, Rhizoma Atractylodis Macrocephalae 50g, Rhizoma Zingiberis 50g, Radix Aconiti Lateralis Preparata 20g, stir-fry Fructus Foeniculi 50g, cervus elaphus linnaeus 15g, Fructus Lycii 50g, Radix Rehmanniae Preparata 40g, Rhizoma Cibotii 30g, Herba Centipedae 60g, Fructus Amomi 20g, Herba Epimedii 30g, Cortex Cinnamomi 20g, Herba Asari 15g, Fructus Psoraleae 50g, Herba Ephedrae 15g, Rhizoma Et Radix Notopterygii 20g, Concha Meretricis seu Cyclinae 30g, Radix Glycyrrhizae 15g.

Embodiment 3

Side's medicine: Radix Ginseng 80g, Poria 100g, Rhizoma Atractylodis Macrocephalae 100g, Rhizoma Zingiberis 80g, Radix Aconiti Lateralis Preparata 30g, stir-fry Fructus Foeniculi 80g, cervus elaphus linnaeus 30g, Fructus Lycii 100g, Radix Rehmanniae Preparata 60g, Rhizoma Cibotii 60g, Herba Centipedae 90g, Fructus Amomi 30 parts, Cortex Cinnamomi 30g, Herba Epimedii 50g, Herba Asari 30g, Fructus Psoraleae 100g, Herba Ephedrae 30g, Rhizoma Et Radix Notopterygii 30g, Concha Meretricis seu Cyclinae 60g, Radix Glycyrrhizae 20g.

The Chinese medicine composition of embodiment 1-3 conventionally can make the dosage forms such as ball, loose, water.Treatment water preparation method be that the clear water adding 4-5 times, above-mentioned Chinese medicine soaks more than 1 hour, decoct about 30 minutes, dry in the air cool rear filtration plastic bag sealing, sterilizing, packaging, every agent 3 bags, every bag of 250ml, ante cibum (medicine) being taken before meal, every day 3 times.As do ball powder type Chinese medicine composition can be pulverized respectively rear mixing thousand mesh sieves sieved after, with Mel with become honeyed pill, the heavy 6-9g of every ball, each 1 ball, every day 3 times.If do capsule formulation can load large size capsule (every is 1.0g), each serving large size capsule 10-15 grain, every day 3 times.Take period: serveing on January is a cycle, and three to May is a course for the treatment of.To take medicine taboo: to avoid eating anything raw or cold, seafood, bean curd, medicated beer, different time strange land fruit and vegerable and blow air-conditioning, fan.

Model case

Case one: Lee, female, 30 years old, cadre, first visit in April, 2008, patient's readme: regular abdominal pain and distension lower abdomen tenesmus over nearly 3 years, sneeze is frequent sooner or later, and with slight headache.Be allergic rhinitis (adenoids) through city's hospital diagnosis, Chinese and western medicine multi-treatment is invalid and go to a doctor.

Body is examined: health is fat or thin moderate, wing of nose both sides (inside and outside fragrant cave) place's flushing, the micro-infantile malnutrition of lip.Inspection of the tongue: corpulent tongue has greasy coating greatly, dark tongue quality.Pulse-taking: both hands cun GUAN-pulse is tightly outstanding and slide, both hands CHI-pulse being weak.Legislation: warming YANG to expel cold, expectorant fall appoint, tonifying vital QI, replenishing vital QI with drugs of warm nature fire from the gater of life, hold up superintend and direct, dredging DU Meridian resisting cold.Method of administration: the prescription drugs of embodiment 1 is made capsule formulation (every capsules 1g), each serving with 10-15, every day three times.Serve on 3 courses for the treatment of through top, subjective symptoms disappears, and follows up a case by regular visits to not recurrence in a year.

Case two: Liu, man, 46 years old, peasant, first visit in August, 2009, patient's readme: often occurred that headache dizziness was weak over the past two years, sneeze took place frequently and flows clear nasal mucus sooner or later, and flu also occurs nocturnal emission frequently often.Be allergic rhinitis through Western medicine diagnose.Through doctor trained in Western medicine antianaphylactic treatment invalid afterwards I go to a doctor.

Body is examined: patient's build is more fat, and complexion is dark yellow.Inspection of the tongue: tongue body is skinny and wizened and aged.Pulse-taking: both hands chi pulse is heavy outstanding tight.Legislation: warming YANG to expel cold, expectorant fall appoint, tonifying vital QI, replenishing vital QI with drugs of warm nature fire from the gater of life, hold up superintend and direct, dredging DU Meridian resisting cold.Method of administration: the prescription drugs of embodiment 2 is made ball powder type, the heavy 6-9g of every ball, each 1 ball, every day 3 times.Serve on 6 courses for the treatment of through top, subjective symptoms disappears, again three courses for the treatment of of administration, follows up a case by regular visits to not recurrence in a year.

Case three: the Meng, female, 32 years old, cadre, first visit in June, 2011.Patient's readme: over nearly 5 years, headache, the phenomenon such as to snore, appear again over nearly 3 years that nasal obstruction, nose pain, nose are cold, in constipation, dysmenorrhea accompany infertile, and sneeze takes place frequently sooner or later.Be that allergic rhinitis nasal vestibule is loose through city's hospital diagnosis, through western medical treatment 3 years invalid afterwards I go to a doctor.

Body is examined: patient Mian Se Koushi is white, and build is partially fat.Inspection of the tongue: corpulent tongue is large, purplish tongue is also bread-like.Pulse-taking: both hands cun, guan and chi, three places at the wrist where the pulse is usually taken three deep-hidden pulse is outstanding tight.Legislation: warming YANG to expel cold, expectorant fall appoint, tonifying vital QI, replenishing vital QI with drugs of warm nature fire from the gater of life, hold up superintend and direct, dredging DU Meridian resisting cold.Method of administration: the prescription drugs of embodiment 3 is made decoction, after taking 6 courses for the treatment of, patient's constipation, abdomen pendant pain, Rhinitis Symptoms disappear, and official holiday is passed through once on the 25-28th.7th course for the treatment of changed the capsule formulation taking embodiment 3, and, patient is from accusing pregnancy, rear fertility one boy baby after clothes soon.Follow up a case by regular visits to and do not recur and accuse recovery from illness for 2 years.

Claims (2)

1. a medicine for treatment of allergic rhinitis, is characterized in that being made up of the raw material of following weight parts proportioning:

Radix Ginseng 30-80 parts, 50-100 parts, Poria, the Rhizoma Atractylodis Macrocephalae 50-100 parts, Rhizoma Zingiberis 30-80 parts, Radix Aconiti Lateralis Preparata 15-30 parts, fry 30-80 parts, Fructus Foeniculi, cervus elaphus linnaeus 10-30 parts, Fructus Lycii 30-100 parts, 20-60 parts, Radix Rehmanniae Preparata, Rhizoma Cibotii 20-60 parts, Herba Centipedae 30-90 parts, Fructus Amomi 15-30 parts, Cortex Cinnamomi 15-30 parts, Herba Epimedii 20-50 parts, Herba Asari 15-30 parts, Fructus Psoraleae 30-100 parts, 10-30 parts, Herba Ephedrae, Rhizoma Et Radix Notopterygii 15-30 parts, Concha Meretricis seu Cyclinae 30-60 parts, 15-20 parts, Radix Glycyrrhizae.

2. the medicine of a kind for the treatment of of allergic rhinitis according to claim 1, is characterized in that being made up of the raw material of following weight parts proportioning:

Radix Ginseng 50 parts, 50 parts, Poria, the Rhizoma Atractylodis Macrocephalae 50 parts, Rhizoma Zingiberis 50 parts, Radix Aconiti Lateralis Preparata 20 parts, stir-fry 50 parts, Fructus Foeniculi, cervus elaphus linnaeus 15 parts, Fructus Lycii 50 parts, 40 parts, Radix Rehmanniae Preparata, Rhizoma Cibotii 30 parts, Herba Centipedae 60 parts, Fructus Amomi 20 parts, Herba Epimedii 30 parts, Cortex Cinnamomi 20 parts, Herba Asari 15 parts, Fructus Psoraleae 50 parts, 15 parts, Herba Ephedrae, Rhizoma Et Radix Notopterygii 20 parts, Concha Meretricis seu Cyclinae 30 parts, 15 parts, Radix Glycyrrhizae.