CN104771734B - A kind of Chinese medicine composition for treating chronic cardiopulmonary disease - Google Patents
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease Download PDFInfo
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Abstract
The invention discloses a kind of technical field for being used to treat the Chinese medicine composition of chronic cardiopulmonary disease, belonging to the medicine for the treatment of chronic cardiopulmonary disease.The present invention composition be：Fruit of negundo 8 12, moxibustion Chinese ephedra 8 12, cassia twig 8 12, radix bupleuri 8 12, the root of purple-flowered peucedanum 8 12, the radix paeoniae rubrathe 8 12, Radix Paeoniae Alba 8 12, the banksia rose 8 12, rhizome of chuanxiong 8 12, grass-leaved sweetflag 8 12, lepidium seed 8 12, wrinkled giant hyssop 8 12, earthworm 8 12, asarum 48, wild ginger 48, peppermint 48, rhizoma zingiberis 48, monkshood 48, blackberry lily 8 12, Folium Elaeagni 8 12, coltsfoot 8 12, periostracum cicada 48, dried orange peel 8 12, the tuber of multiflower knotweed 8 12, Poria cocos 8 12, honey-fried licorice root 48, Radix Salviae Miltiorrhizae 8 12, amethyst 8 12, are parts by weight above.Medicine source broad covered area of the present invention, compatibility science, lesion depths of going directly, nurses one's health inside of human body function, evident in efficacy, quick, has no toxic side effect.
Description
Technical field
Technical field the invention belongs to the medicine for treating chronic cardiopulmonary disease, particularly relates to a kind of chronic cardiopulmonary disease for the treatment of
Chinese medicine composition.
Background technology
The full name of chronic cardiopulmonary disease is chronic cor pulmonale, is by the chronic disease of chest exterior feature, lung and pulmonary arterial vascular
The pulmonary vascular resistance that change is drawn increases, pulmonary hypertension, and then makes plump right ventricle, expansion, right sided heart failure even occurs
Heart disease.Chronic cor pulmonale is high in our incidence, especially in cold, humid area and mountain area, miner and smoking
Person's incidence higher, according to the statistics of China in recent years, illness rate is 0.4 ~ 0.5% to pulmonary heart disease every year on average.The diseased age is mostly 40
More than year, the age is bigger, and illness rate is higher.Acute attack is common with winter, spring, and acute respiratory infection is often acute attack
Inducement, often results in lung, heart failure and is difficult to the multiple organ failure reversed, case fatality rate is higher.
At present, the mechanism of chronic cardiopulmonary disease is still not clear；The method of clinical treatment chronic cardiopulmonary disease mainly uses
The conventional anti-infections such as digitalis, diuretics, vasodilator, antibiotic, antiarrhythmic drug, still, these curative effect of medication
Slowly, toxic side effect is easily caused, effect is undesirable.Currently, also there are some Chinese medicines for being used to treat chronic cardiopulmonary disease, still,
These Chinese medicines there is also therapeutic effect it is not obvious enough and take effect it is slower so that large quantities of Patients with Chronic Cor Pulmonale are for a long time in chest
Subsist in vexed, palpitaition, expiratory dyspnea, edema of lower extremity, shortness of breath of coughing, cannot alleviate, it is heavy to be brought to patient and its family members for many years
The burden of weight.
The content of the invention
The present invention provide it is a kind of be used to treat the Chinese medicine composition of chronic cardiopulmonary disease, solve treat in the prior art it is chronic
The problem of curative effect of medication of pulmonary heart disease is poor, slowly effect and toxic side effect are big.
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease of the present invention, it is mainly subject to reality by the following technical programs
Existing：
The Chinese medicine composition of the present invention, including the raw material of following parts by weight are made：8-12 parts of fruit of negundo, moxibustion Chinese ephedra 8-12
Part, 8-12 parts of cassia twig, 8-12 parts of radix bupleuri, 8-12 parts of the root of purple-flowered peucedanum, 8-12 parts of the radix paeoniae rubrathe, 8-12 parts of Radix Paeoniae Alba, 8-12 parts of the banksia rose, rhizome of chuanxiong 8-12
Part, 8-12 parts of grass-leaved sweetflag, 8-12 parts of lepidium seed, 8-12 parts of wrinkled giant hyssop, 8-12 parts of earthworm, 4-8 parts of asarum, 4-8 parts of wild ginger, peppermint 4-
8 parts, 4-8 parts of rhizoma zingiberis, 4-8 parts of monkshood, 8-12 parts of blackberry lily, 8-12 parts of Folium Elaeagni, 8-12 parts of coltsfoot, 4-8 parts of periostracum cicada, dried orange peel 8-12
Part, 8-12 parts of the tuber of multiflower knotweed, 8-12 parts of Poria cocos, 4-8 parts of honey-fried licorice root, 8-12 parts of Radix Salviae Miltiorrhizae, 8-12 parts of amethyst.
The Chinese medicine composition medicine source broad covered area of the present invention, compatibility is scientific and reasonable, brings out the best in each other, and plays righting altogether and sustains losses in business, is warm
Lung resolving sputum, evacuation fever and chills, the work(of inducing meastruation to relieve menalgia, tonifying spleen and stomach, lesion depths of going directly, to the cause of disease of chronic cor pulmonale into
Row is targetedly put in poison；At the same time, additionally it is possible to which conditioning inside of human body function comprehensively, strengthens the immunity of human body, improves the anti-of human body
Sick ability；Treatment for chronic cardiopulmonary disease have it is evident in efficacy, it is quick, the characteristics of having no toxic side effect.
In the Chinese medicine composition of the present invention, fruit of negundo：It is acrid flavour, warm-natured；Return lung, stomach, Liver Channel；With expelling pathogenic wind from the body surface, cough-relieving
Relieving asthma, the effect of qi-regulating helps digestion, analgesic；Cold is cured mainly, is coughed, asthma, acid regurgitation of having a stomachache, indigestion, dyspepsia rush down dysentery, courage
Capsulitis, gall stone, hernia.
In the Chinese medicine composition of the present invention, moxibustion Chinese ephedra：Pungent, the slight bitter of property, taste temperature；Return lung, bladder warp；With sweating cold dispelling,
Freeing lung and relieving asthma, inducing diuresis for removing edema the effect of；Cure mainly exterior syndrome due to wind-cold, card of breathing with cough, oedema etc..
In the Chinese medicine composition of the present invention, cassia twig：Pungent, sweet in flavor, the tepor of property；The thoughts of returning home, lung, bladder warp；With sweating expelling pathogenic factors from muscles and skin,
The effect of warming meridians and promoting circulation of qi, helps yang transforming qi, eliminating cold to stop pain；Cure mainly exterior syndrome due to wind-cold, numbness and ache of cold dampness, peripheral coldness, closed dysmenorrhea, abdominal mass
Caking, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination.
In the Chinese medicine composition of the present invention, radix bupleuri：Bitter, is slightly cold；Return liver, gallbladder channel；With with inducing diaphoresis, soothing the liver, rising Yang
The effect of；Cure mainly cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, rectal prolapse.
In the Chinese medicine composition of the present invention, the root of purple-flowered peucedanum：Bitter, property is pungent, is slightly cold；Return lung, spleen, Liver Channel；With dispelling wind and heat from the body, drop
The effect of gasification phlegm；Affection of exogenous wind-heat is cured mainly, lung heat phlegm is strongly fragrant, cough and phlegm, yellow and sticky sputum, inverse deficiency of food, and chest diaphragm is full vexed；For wind
Heat cough abundant expectoration, phlegm heat panting are expired, cough up phlegm yellow thick.
In the Chinese medicine composition of the present invention, the radix paeoniae rubrathe：Cold nature, bitter；Enter Liver Channel；It is promoting blood circulation and removing blood stasis with clearing heat and cooling blood, only
The effect of pain；Cure mainly blood-heat bleeding, hematemesis hair spot, blood stasis closed, traumatic injury, pathopyretic ulcer, irascibility hot eyes.
In the Chinese medicine composition of the present invention, Radix Paeoniae Alba：Bitter, acid, be slightly cold；Return liver, the spleen channel；The moon is held back with blood-nourishing, soft liver is stopped
Bitterly, the effect of suppressing liver-YANG；Liver-blood deficiency and deficiency of blood irregular menstruation are cured mainly, the chest side of body epigastric pain or four limbs contraction of incoordination between the liver and the spleen are anxious
Pain, the dizziness of having a headache of liver-yang hyperactivity.
In the Chinese medicine composition of the present invention, the banksia rose：It is acrid flavour, hardship, warm-natured；Have effects that to lead in promoting qi circulation and relieving pain, tune stagnant；It is main
Control born of the same parents and coerce weight after turgor foot, abdominal distention, vomiting and diarrhea, dysentery.
In the Chinese medicine composition of the present invention, rhizome of chuanxiong：It is sweet in flavor, pungent, warm；Return liver, the heart, the spleen channel；With promoting blood circulation and stopping pain, tune of enriching blood
Through the effect of relaxing bowel；Cure mainly dizziness due to deficiency of blood, irregular menstruation, amenorrhoea, dysmenorrhoea, sallow complexion, asthenia cold abdominalgia, traumatic injury,
Arthralgia pain due to rheumatism, ulcer sores, dry constipation of intestines.
In the Chinese medicine composition of the present invention, grass-leaved sweetflag：The pungent, bitter of property, tepor；The thoughts of returning home, stomach；With dampness elimination appetizing, open
The effect of key slit phlegm, inducing resuscitation intelligence development；Cure mainly gastral cavity ruffian is not hungry, apnea, coma epilepsy, forgetfulness and deafness.
In the Chinese medicine composition of the present invention, lepidium seed：It is acrid flavour, hardship, cold in nature；Return lung, bladder warp；With removing heat from lung and relieving asthma, profit
The effect of water is subsided a swelling；Cure mainly phlegm and retained fluid to stop accumulating, fullness sensation in chest stops up the illnesss such as stagnant, cough and asthma, the edema of the face, chest and abdomen ponding, difficult urination.
In the Chinese medicine composition of the present invention, wrinkled giant hyssop：It is acrid flavour, warm-natured；Return stomach, lung, the spleen channel；With eliminating dampness with aromatics, appetizing stops
The effect of vomitting, delivering relieving summer-heat；Turbi damp obstructing in middle-JIAO is cured mainly, the vomiting of gastral cavity ruffian, summer-heat and damp burnout is uncomfortable in chest not relax, and cold-dampness closes heat, and abdominal pain is vomited and diarrhoea,
Nasosinusitis headache.
In the Chinese medicine composition of the present invention, earthworm：Taste is salty, cold in nature；Return liver, spleen, bladder warp；Calm the frightened with heat-clearing, dredging collateral,
Relieving asthma, the effect of diuresis；Cure mainly high fever frightened epilepsy, demented, blood stagnancy due to deficiency of QI, hemiplegia, bi Zheng, lung heat asthma, difficult urination, urine
Close obstructed etc..
In the Chinese medicine composition of the present invention, asarum：Acrid flavour, it is warm-natured；The thoughts of returning home, lung, kidney channel；Relieved pain with expelling wind and clearing away cold, temperature
The effect of lungization drink is sensible；Cure mainly catch cold, have a headache, having a toothache, chill temperature numbness, phlegm and retained fluid cough and asthma, nasal obstruction nasosinusitis, eye of wind mesh screen,
Ear closes pharyngalgia, aphtha halitosis.
In the Chinese medicine composition of the present invention, wild ginger：It is acrid flavour, warm-natured；Enter lung, liver, kidney, bladder warp；With relieve heat by trembling with fear, disappear
The effect of phlegm row water, promoting blood circulation, relievings asthma, analgesic therapy；Cure mainly anemofrigid cold, sputum cough, oedema, rheumatism, traumatic injury, headache, dental caries
Dentalgia, eruptive disease abdominal pain.
In the Chinese medicine composition of the present invention, peppermint：Property is pungent, and taste is cool；Enter lung channel, Liver Channel；With dispelling wind and heat from the body, clear sharp head
The effect of mesh, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi；Dispelling wind is cured mainly, radiates, ward off dirty, removing toxic substances, affection of exogenous wind-heat, headache, abscess of throat, food
Stagnant gas is swollen, aphtha, toothache, sore scabies, urticaria, warm disease from the beginning of, rubella itch, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest.
In the Chinese medicine composition of the present invention, rhizoma zingiberis：Acrid flavour, property heat；Returns spleen, stomach, the heart, lung channel；With warming spleen and stomach for dispelling cold, Hui Yang
Promote blood circulation, eliminating dampness dissolving phlegm, Wenfei of drink the effect of；Coldness and pain in the epigastrium is cured mainly, is vomitted, diarrhea, yang depletion is fainted inverse, and cold drink is breathed with cough, cold-dampness numbness
Bitterly.
In the Chinese medicine composition of the present invention, monkshood：Pungent, sweet in flavor, the big heat of property；The thoughts of returning home, kidney, the spleen channel；With recuperating depleted yang, mend
The effect of fire is supporing yang, eliminating cold to stop pain；Exessive yin refusing yang, loss of YANG due to profuse perspiration is cured mainly, inverse, cold weak pulse of limb of fainting of vomiting and diarrhoea, trusted subordinate's crymodynia, cold dysentery,
Tinea pedis oedema, wind-cold-dampness arthralgia, impotence, Gong Leng, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors.
In the Chinese medicine composition of the present invention, blackberry lily：It is bitter, cold in nature；Enter lung, Liver Channel；With clearing heat and detoxicating, throat, disappears
The effect of sputum；Cure mainly abscess of throat, phlegm water is breathed with cough.
In the Chinese medicine composition of the present invention, Folium Elaeagni：It is sour, mild-natured；Enter lung channel；With relieving cough and asthma, hemostasis, removing toxic substances
Effect；Cough due to deficiency of the lung is cured mainly, is panted, hemoptysis, spits blood, traumatic hemorrhage, ulcer, hemorrhoid gall.
In the Chinese medicine composition of the present invention, coltsfoot：Pungent, the taste temperature of property；It is distributed in lung channel；With preventing phlegm from forming and stopping coughing, gas under antibechic, moistening lung
The effect of eliminating the phlegm；Cough is cured mainly, is panted, consumptive lung disease, cough is spat the diseases such as blood, more than particularly suitable for chronic cough of deficiency lung.
In the Chinese medicine composition of the present invention, periostracum cicada：It is sweet in flavor, property is pungent, micro- cool；Return lung, Liver Channel；With dispelling wind and heat from the body, promoting eruption
The effect of relieving sore-throat, removing nebula, expelling wind and relieving convulsion, cure mainly anemopyretic cold, cough, dizzy, measles without adequate eruption, pharyngalgia hoarse voice, hot eyes screen
Hinder, itch before wind, pediatric epilepsy scared, the morbid night crying of babies, lockjaw.
In the Chinese medicine composition of the present invention, dried orange peel：Warm-natured, acrid flavour, bitter；Returns spleen, stomach, lung channel；With regulating qi-flowing for strengthening spleen, adjust
In, the effect of eliminating dampness, resolving sputum；The abdominal fullness and distention or pain, indigestion of the taste stagnation of the circulation of vital energy are cured mainly, abdominal distension uncomfortable in chest in wet turbid resistance,
Indigestion and loss of appetite loose stool, the cough and asthma of phlegm obstructing lung；For chest gastral cavity turgor, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
In the Chinese medicine composition of the present invention, the tuber of multiflower knotweed：It is sweet in flavor, bitter, puckery, mild-natured, tepor；The thoughts of returning home, liver, kidney, large intestine channel；Have
Detoxify, the carbuncle that disappears, relax bowel, the effect of filling liver kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles；Cure mainly scrofula sore carbuncle, rubella itch, intestines
Dry constipation；Under blood deficiency chlorosis, dizziness and tinnitus, poliosis, soreness and weakness of waist and knees, extremity numbness, uterine bleeding band, chronic malaria body void etc..
In the Chinese medicine composition of the present invention, Poria cocos：It is sweet in flavor, light, it is mild-natured；Enter the heart, lung, the spleen channel；With eliminating dampness and diuresis, invigorating the spleen
And stomach, the effect of antitoxic heart-soothing and sedative；Difficult urination is cured mainly, oedema turgor, phlegm and retained fluid cough is inverse, vomits inverse, vomiting during early pregnancy, diarrhea, seminal emission, stranguria with turbid discharge,
Palpitation with fear, it is forgetful to wait disease.
In the Chinese medicine composition of the present invention, honey-fried licorice root：Nature and flavor are sweet, flat；The thoughts of returning home, lung, spleen and stomach；With tonifying spleen and stomach,
The effect of Yiqi and vein recovery；Weakness of the spleen and the stomach, lassitude hypodynamia is cured mainly, severe palpilation, intermittent pulse, can solve monkshood poison.
In the Chinese medicine composition of the present invention, Radix Salviae Miltiorrhizae：Bitter, is slightly cold；Converge to heart and liver channels；It is inducing meastruation to relieve menalgia with promoting blood circulation,
The effect of relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle；Cure mainly and be used for chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia,
Irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative.
In the Chinese medicine composition of the present invention, amethyst：It is sweet in flavor, it is pungent, it is warm-natured；Enter the heart, liver, lung, kidney channel；With relieving palpitation, peace
The effect of god, lowering the adverse flow of qi, warm uterus；Cure mainly palpitaition, palpitation, frightened epilepsy, lung cold cough with dyspnea, woman's fertility.
Preferably, Chinese medicine composition of the invention, including the raw material of following parts by weight are made：10 parts of fruit of negundo, moxibustion Chinese ephedra
10 parts, 10 parts of cassia twig, 10 parts of radix bupleuri, 10 parts of the root of purple-flowered peucedanum, 10 parts of the radix paeoniae rubrathe, 10 parts of Radix Paeoniae Alba, 10 parts of the banksia rose, 10 parts of rhizome of chuanxiong, grass-leaved sweetflag 10
Part, 10 parts of lepidium seed, 10 parts of wrinkled giant hyssop, 10 parts of earthworm, 6 parts of asarum, 6 parts of wild ginger, 6 parts of peppermint, 6 parts of rhizoma zingiberis, 6 parts of monkshood, blackberry lily
10 parts, 10 parts of Folium Elaeagni, 10 parts of coltsfoot, 6 parts of periostracum cicada, 10 parts of dried orange peel, 10 parts of the tuber of multiflower knotweed, 10 parts of Poria cocos, 6 parts of honey-fried licorice root, Radix Salviae Miltiorrhizae 10
Part, 10 parts of amethyst.
The traditional Chinese medical science thinks, chronic cardiopulmonary disease be bronchus pneumonopathy and Pulmonary vascular disease caused by heart disease, controlling to declare clearly
Lung is supported, Wen Yangli water is promoting blood circulation and removing blood stasis.The Chinese medicine composition of the present invention is exactly to be developed meticulously according to this traditional Chinese medical science theory, first
First through lesion depths, carries out specific aim prescribe medicine to pathogeny, has reached the effect of clearing heat and detoxicating, antibacterial anti-inflammatory and resolving sputum and relieving asthma；
Then, the inside function of human body is nursed one's health comprehensively, there is tonifying Qi kidney-nourishing, mends fire supporing yang and antitoxic heart-soothing and sedative, improved
The overall disease resistance of human body.According to clinical verification, the cure rate of traditional Chinese medicine composition for treating chronic cardiopulmonary disease of the invention is high, always
It is efficient up to 99%, efficacy stability.
Specifically, in Chinese medicine composition of the invention, the formulation of the Chinese medicine composition is decoction, pill, granule, glue
One kind in wafer or tablet.A variety of formulations can be made in the Chinese medicine composition of the present invention, carried out according to the situation of patient itself
Select, it is convenient to take, significantly reduce the psychological burden of patient.
Preferably, in medicine pill of the invention, the pill is sophora flower honeyed bolus, is 2g per ball weight.Sophorae honey is clear
It is cool, have sophora flower diuresis of drying, cooling blood and hemostasis the effect of, the normal resistivity of capillary can be kept, have vasodilator,
Improve blood circulation, prevent vascular sclerosis, reduce the effect such as blood fat and blood pressure, and for pre- anti-stroke, at the same also have heat-clearing bowl spares,
The effect of detoxify and moisturize, especially suitable for chronic and edible, the especially suitable the elderly of cardiovascular patient.
The usage of the Chinese medicine composition of the present invention：One after each meal, three times a day, one week as a treatment course.
Beneficial effects of the present invention：The Chinese medicine composition medicine source broad covered area of the present invention, compatibility is scientific and reasonable, mutually benefits
It is evident, the work(that righting sustains losses in business, is warming lung and reducing phlegm, evacuating fever and chills, inducing meastruation to relieve menalgia, tonifying spleen and stomach is played altogether, lesion depths of going directly, to chronic pulmonary
The property cardiopathic cause of disease in source is targetedly put in poison, and has reached the effect of clearing heat and detoxicating, antibacterial anti-inflammatory and resolving sputum and relieving asthma；Together
When, additionally it is possible to conditioning inside of human body function comprehensively, has the function that tonifying Qi kidney-nourishing, mends fire supporing yang and antitoxic heart-soothing and sedative, enhances people
The immunity of body, improves the disease resistance of human body；Treatment for chronic cardiopulmonary disease has evident in efficacy, quick, healing
Rate is high, and efficacy stability is convenient to take, the characteristics of having no toxic side effect.
Embodiment
Technical scheme is clearly and completely described below in conjunction with specific embodiment, it is clear that described
Embodiment be only part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ability
Domain those of ordinary skill all other embodiments obtained without creative efforts, belong to guarantor of the present invention
The scope of shield.
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, including the raw material of following parts by weight are made：8-12 parts of fruit of negundo,
8-12 parts of moxibustion Chinese ephedra, 8-12 parts of cassia twig, 8-12 parts of radix bupleuri, 8-12 parts of the root of purple-flowered peucedanum, 8-12 parts of the radix paeoniae rubrathe, 8-12 parts of Radix Paeoniae Alba, banksia rose 8-12
Part, 8-12 parts of rhizome of chuanxiong, 8-12 parts of grass-leaved sweetflag, 8-12 parts of lepidium seed, 8-12 parts of wrinkled giant hyssop, 8-12 parts of earthworm, 4-8 parts of asarum, wild ginger
4-8 parts, 4-8 parts of peppermint, 4-8 parts of rhizoma zingiberis, 4-8 parts of monkshood, 8-12 parts of blackberry lily, 8-12 parts of Folium Elaeagni, 8-12 parts of coltsfoot, periostracum cicada 4-
8 parts, 8-12 parts of dried orange peel, 8-12 parts of the tuber of multiflower knotweed, 8-12 parts of Poria cocos, 4-8 parts of honey-fried licorice root, 8-12 parts of Radix Salviae Miltiorrhizae, 8-12 parts of amethyst.
Further, Chinese medicine composition of the invention, including the raw material of following parts by weight are made：10 parts of fruit of negundo, moxibustion fiber crops
10 parts yellow, 10 parts of cassia twig, 10 parts of radix bupleuri, 10 parts of the root of purple-flowered peucedanum, 10 parts of the radix paeoniae rubrathe, 10 parts of Radix Paeoniae Alba, 10 parts of the banksia rose, 10 parts of rhizome of chuanxiong, grass-leaved sweetflag
10 parts, 10 parts of lepidium seed, 10 parts of wrinkled giant hyssop, 10 parts of earthworm, 6 parts of asarum, 6 parts of wild ginger, 6 parts of peppermint, 6 parts of rhizoma zingiberis, 6 parts of monkshood, penetrate
10 parts dry, 10 parts of Folium Elaeagni, 10 parts of coltsfoot, 6 parts of periostracum cicada, 10 parts of dried orange peel, 10 parts of the tuber of multiflower knotweed, 10 parts of Poria cocos, 6 parts of honey-fried licorice root, Radix Salviae Miltiorrhizae
10 parts, 10 parts of amethyst.
Further, in Chinese medicine composition of the invention, the formulation of the Chinese medicine composition is decoction, pill, particle
One kind in agent, capsule or tablet.
Yet further, in medicine pill of the invention, the pill is sophora flower honeyed bolus, is 2g per ball weight.
Embodiment one
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, including following raw material：Fruit of negundo 8g, moxibustion Chinese ephedra 8g, cassia twig 8g,
It is radix bupleuri 8g, root of purple-flowered peucedanum 8g, radix paeoniae rubrathe 8g, Radix Paeoniae Alba 8g, banksia rose 8g, rhizome of chuanxiong 8g, grass-leaved sweetflag 8g, lepidium seed 8g, wrinkled giant hyssop 8g, earthworm 8g, thin
Pungent 4g, wild ginger 4g, peppermint 4g, rhizoma zingiberis 4g, monkshood 4g, blackberry lily 8g, Folium Elaeagni 8g, coltsfoot 8g, periostracum cicada 4g, dried orange peel 8g, tuber of multiflower knotweed 8g,
Poria cocos 8g, honey-fried licorice root 4g, Radix Salviae Miltiorrhizae 8g, amethyst 8g.
1500mL water is added in above-mentioned raw materials, is decocted, seethes with excitement after 30min, pours out decoction liquor；Remaining filter residue is continued
Add water to cook, decoct 3 times altogether；Decoction liquor is merged, is concentrated into 150mL, is divided into three times, one after each meal, three times a day, one week
It is as a treatment course.
Embodiment two
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, including following raw material：Fruit of negundo 10g, moxibustion Chinese ephedra 10g, cassia twig
10g, radix bupleuri 10g, root of purple-flowered peucedanum 10g, radix paeoniae rubrathe 10g, Radix Paeoniae Alba 10g, banksia rose 10g, rhizome of chuanxiong 10g, grass-leaved sweetflag 10g, lepidium seed 10g, wrinkled giant hyssop
10g, earthworm 10g, asarum 6g, wild ginger 6g, peppermint 6g, rhizoma zingiberis 6g, monkshood 6g, blackberry lily 10g, Folium Elaeagni 10g, coltsfoot 10g, periostracum cicada
6g, dried orange peel 10g, tuber of multiflower knotweed 10g, Poria cocos 10g, honey-fried licorice root 6g, Radix Salviae Miltiorrhizae 10g, amethyst 10g.
By above-mentioned raw materials attrition grinding, it is uniformly mixed, adds sophorae honey, pill is made, which is sophora flower honeyed bolus, per ball
Weight is 2g, and each taking 4 balls, one after each meal, three times a day, one week as a treatment course.
Embodiment three
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, including following raw material：Fruit of negundo 12g, moxibustion Chinese ephedra 12g, cassia twig
12g, radix bupleuri 12g, root of purple-flowered peucedanum 12g, radix paeoniae rubrathe 12g, Radix Paeoniae Alba 12g, banksia rose 12g, rhizome of chuanxiong 12g, grass-leaved sweetflag 12g, lepidium seed 12g, wrinkled giant hyssop
12g, earthworm 12g, asarum 8g, wild ginger 8g, peppermint 8g, rhizoma zingiberis 8g, monkshood 8g, blackberry lily 12g, Folium Elaeagni 12g, coltsfoot 12g, periostracum cicada
8g, dried orange peel 12g, tuber of multiflower knotweed 12g, Poria cocos 12g, honey-fried licorice root 8g, Radix Salviae Miltiorrhizae 12g, amethyst 12g.
Above-mentioned raw materials are soaked, are distilled, are concentrated, are dried, tabletting, tablet is made, every weighs 1g, each taking 4, after meal
Take, three times a day, one week as a treatment course.
Example IV
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, including following raw material：Fruit of negundo 9g, moxibustion Chinese ephedra 9g, cassia twig 9g,
Radix bupleuri 9g, root of purple-flowered peucedanum 11g, radix paeoniae rubrathe 11g, Radix Paeoniae Alba 11g, banksia rose 11g, rhizome of chuanxiong 9g, grass-leaved sweetflag 9g, lepidium seed 11g, wrinkled giant hyssop 11g, earthworm
9g, asarum 5g, wild ginger 7g, peppermint 7g, rhizoma zingiberis 5g, monkshood 5g, blackberry lily 9g, Folium Elaeagni 11g, coltsfoot 11g, periostracum cicada 5g, dried orange peel 9g,
Tuber of multiflower knotweed 9g, Poria cocos 11g, honey-fried licorice root 7g, Radix Salviae Miltiorrhizae 11g, amethyst 9g.
Above-mentioned raw materials to be added into water, are soaked, are distilled, are concentrated, spray drying, is made granule, often packs 2g, each taking
2 bags, one after each meal, three times a day, one week as a treatment course.
Embodiment five
A kind of Chinese medicine composition for treating chronic cardiopulmonary disease, including following raw material：Fruit of negundo 11g, moxibustion Chinese ephedra 11g, cassia twig
11g, radix bupleuri 11g, root of purple-flowered peucedanum 9g, radix paeoniae rubrathe 9g, Radix Paeoniae Alba 9g, banksia rose 9g, rhizome of chuanxiong 11g, grass-leaved sweetflag 11g, lepidium seed 9g, wrinkled giant hyssop 9g,
Imperial 11g, asarum 7g, wild ginger 5g, peppermint 5g, rhizoma zingiberis 7g, monkshood 7g, blackberry lily 11g, Folium Elaeagni 9g, coltsfoot 9g, periostracum cicada 7g, dried orange peel
11g, tuber of multiflower knotweed 11g, Poria cocos 9g, honey-fried licorice root 5g, Radix Salviae Miltiorrhizae 9g, amethyst 11g.
Above-mentioned raw materials are soaked, are distilled, are concentrated, it is dry, load capsule, capsule is made, every capsule fills 1.0g, every time
4 are taken, one after each meal, three times a day, one week as a treatment course.
With reference to specific test example, the present invention is further explained, wherein, include the present invention Chinese medicine composition animal
Toxicity test, pharmacodynamics test and clinical observation experiment.
Animal toxicity test
The embodiment of the present invention one is arrived to the Chinese medicine composition of embodiment five, has carried out multiple animal toxicity test respectively；Often
During secondary experiment, rabbit 20 is taken, male and female dual-purpose, weight 2.0-2.5kg, is divided into two groups, every group 10, one of which is overdose
Test group, another group is normal amount test group, and overdose test group dosage is 8.0g/kg, and normal amount test group dosage is 4.0g/
Kg, administering mode are administered for administration by gavage, once in the morning and once at night, continuously take 10 days, the reaction of observation administration daily；Test of many times
The result shows that, two groups of rabbit spirit, activity, diet, excretion are normal；Dissect, visually examines main inside internal organs, not
See exception；Therefore, the Chinese medicine composition is without bad toxic side effect.
Animal pharmacodynamics test
Effect of the Chinese medicine composition of the present invention to pulmonary heart disease rat model pulmonary hypertension
Healthy adult SD rat 80 is selected, half male and half female, weight 180-250g, is randomly divided into 8 groups, i.e., one right
According to group, a model group and 6 administration groups, wherein, administration group includes the embodiment of the present invention one and arrives the administration group of embodiment five, city
Sell the Chinese medicine administration group of certain treatment chronic cardiopulmonary disease；The ethanol of equivalent is being subcutaneously injected in the rat normally organized：Physiological saline=2:8
Mixed solution, disposably monocrotaline is being subcutaneously injected in the rat of model group and administration group（MCT, with ethanol：Physiological saline=
2:8 be solvent）60mg/Kg, the 8th day after modeling success starts gastric infusion, the identical quantity of the daily gavage of control group and model group
Physiological saline, once a day, successive administration three weeks.
1h after the last administration, by rat weight, anesthesia takes center right side longitudinal cut about 0.5cm, and separation is exposed outside right neck
Vein, ligatures distal end, carefully cuts " V " type osculum with eye scissors on the vascular wall at ligation；, will using right cardiac catheter
Special good PE50 pipes are full of heparin-saline in advance（Avoid in tube chamber that there are bubble）, intubation, and with surgical thread by blood vessel and
PE50 pipes gently ligature, and slowly push ahead, PE50 pipes is entered right ventricle from atrium dextrum, finally reach pulmonary artery, this process
Need close observation pressure size and waveform in record system, according to conduit be inserted into length, pulmonary artery pressure waveform and
Pressure value judges whether conduit has reached pulmonary artery, and carries out corresponding pressure and waveform recording, and average lung is recorded after stablizing
Angiosthenia（mPAP）, and X is used to experimental result2The method of inspection is analyzed.
After rat modeling success, body mass ratio Normal group substantially mitigates, and different degrees of appearance lung rale, and land
It is continuous death occur.The main pathological change of chronic cardiopulmonary disease is pulmonary hypertension（PAH）With the aspect of heart disease two, wherein PAH
It is the key link and prerequisite in chronic cardiopulmonary disease pathogenic process.
Influence of 1 different pharmaceutical of table to adult rat pulmonary artery blood pressure
Remarks：Compared with model group, * --- P<0.05；**——P<0.01.
From table 1 it follows that compared with model group, of the invention five kinds of Chinese medicine compositions can significantly decrease rat
The death rate, the weight of rat, which is reduced, certain inhibitory action, additionally it is possible to significantly decreases the average right ventricle of rat
Pressure（mRVP）, mean pulmonary arterial pressure（mPAP）With maximum pulmonary arterial pressure（Max mPAP）, and show as conspicuousness reduction（P<
0.01）；Compared with the Chinese medicine of certain commercially available treatment chronic cardiopulmonary disease, of the invention five kinds of Chinese medicine compositions have obvious excellent
Gesture, i.e. rats death rate further reduce, and further reduces mRVP, mPAP and Max mPAP of rat；Therefore, it is of the invention
Five kinds of Chinese medicine compositions there is the advantage of obvious treatment rat chronic pulmonary heart disease.
Clinical observation experiment
Patient data
The Patients with Chronic Cor Pulmonale 600 of 40-80 Sui is randomly selected, wherein, man 300, female 300, average age is
56.7 years old, the course of disease 1 year to 10 years, average course of disease 5.6 years；The last fortnight of experiment, continuously observes the crowd, records symptom
And change, it is divided into six groups according to the method for male to female ratio, ratio of age and course of disease balanced proportion, is respectively a control group and five
A treatment group, every group each 100, does not have otherness statistically between six groups of patients, six groups of patients meet chronic pulmonary
The diagnostic criteria of worry；This six groups of patients once use the treatment methods such as Western medicine or Chinese medicine before this treatment is received, still,
Effect is not notable, easily recurrence, it is impossible to except root.
Diagnostic criteria
Cure：Cough is obviously improved, and electrocardio diagram coronary artery blood supply is obviously improved, and malaise symptoms disappear, energy and body
Power is remarkably reinforced；
Effectively：Cough symptom mitigates, and electrocardio diagram artery chronic blood supply improves, and malaise symptoms mitigate or part disappears
Lose, energy and muscle power enhancing；
It is invalid：Malaise symptoms are unchanged or aggravate.
Therapeutic scheme
Control group：Patient takes Chinese medicine of certain commercially available treatment chronic cardiopulmonary disease orally, it is decoction, one after each meal, one day three
Secondary, each 50mL, a month as a treatment course, continuously takes three courses for the treatment of；
Treatment group：Patient takes the embodiment of the present invention one orally to five kinds of Chinese medicine compositions of embodiment five respectively, one after each meal,
Three times per day, one week it is as a treatment course, continuously take three courses for the treatment of.
Daily follow-up once, is evaluated respectively before medication and after medication, after treatment finishes, continues follow-up 3 years, treatment
Before, further consultation and when follow-up fill in case report form.
All subjects must not merge the medicine and possibility of any other treatment chronic cardiopulmonary disease of use during experiment
Influence clinical efficacy and the medicine of adverse reaction evaluation.
Therapeutic effect
2 clinical treatment outcome summary sheet of table
Clinical observation result
Six groups of clinical treatment outcomes collect as shown in table 2, as can be seen from Table 2, of the invention five kinds of Chinese medicine compositions pair
Treatment chronic cardiopulmonary disease is respectively provided with the effect of fine, and clearly, cure rate is significantly raised for advantage, total effective rate increase, invalid
Rate substantially reduces, and cure rate is up to more than 80%, total effective rate 99%；Short treating period, it is quick, mild in medicine property and, it is convenient to take, significantly
Alleviate the pain of patient；Curative effect is stablized, and has no toxic side effect, treats both principal and secondary aspect of disease.
Model case
Case 1：Liu XX, man, 55 years old, peasant, cough, more phlegm, uncomfortable in chest, 5 years nervous, cause drenched with rain and catches cold within one month
Above-mentioned symptom aggravates afterwards, and abdominal distension occurs, loses the appetite, dizzy, headache, and the state of mind is very poor.It is chronic cardiopulmonary disease after diagnosing,
Informal dress digitalis, the medicine of diuretics, only take stopgap measures, do not effect a permanent cure, Chang Fanfu.Take the present invention Chinese medicine composition, daily three
It is secondary, one after each meal；After taking a course for the treatment of, cough and expectoration symptom mitigate；After taking three courses for the treatment of, cough is obviously improved, abdomen
Swollen, loss of appetite, dizziness and headache syndromes disappear, and electrocardio diagram coronary artery blood supply is obviously improved, energy and the obvious increasing of muscle power
By force；Rest after a week, and continues to take three courses for the treatment of, to strengthen consolidating；After drug withdrawal, follow-up 3 years, no relapse, the state of mind
Very well.
Case 2：Lee XX, man, 75 years old, over more than 10 years, there is cough, the dense phlegm of phlegm yellow, and gas occur repeatedly in retired worker
It is short, the symptom such as precordialgia, weak, uncomfortable in chest, activity or symptom is obvious after suffering from cold.It is chronic cardiopulmonary disease after diagnosing.Took
The Chinese herbal medicine of many treatment chronic cardiopulmonary diseases, effect unobvious, easily recur after drug withdrawal.The Chinese medicine composition of the present invention is taken, often
Day three times, one after each meal；After taking a course for the treatment of, cough and expectoration symptom are eased；After taking three courses for the treatment of, cough and cough
Phlegm is obviously improved, and the symptom such as pained, weak, uncomfortable in chest disappears, and electrocardio diagram coronary artery blood supply is obviously improved, and energy and muscle power are bright
Aobvious enhancing；Rest after a week, and continues to take three courses for the treatment of, to strengthen consolidating；After drug withdrawal, follow-up 2 years, no relapse, spirit
It is in good shape.
Case 3：Ginger XX, female, 43 years old, enterprise staff, in recent years, cough, expectoration all day, symptom was aggravated when from morning, activity
Such as run, climb the mountain afterwards, skelping and feel palpitaition, shortness of breath, can alleviate after rest.It is chronic cardiopulmonary disease after diagnosing, informal dress is used
Antibiotic etc. is anti-infective, antiarrhythmic drug, does not effect a radical cure always.The Chinese medicine composition of the present invention is taken, three times a day, after meal
Take；After taking a course for the treatment of, cough and expectoration symptom are eased from morning；After taking three courses for the treatment of, cough and expectoration are obvious
Improve, the symptom such as palpitaition, shortness of breath disappears, and electrocardio diagram coronary artery blood supply is obviously improved, and energy and muscle power are remarkably reinforced；Rest
After a week, and continue to take three courses for the treatment of, to strengthen consolidating；After drug withdrawal, follow-up 1 year, no relapse, the state of mind is fine.
Therefore, the beneficial effects of the invention are as follows：The Chinese medicine composition medicine source broad covered area of the present invention, compatibility is scientific and reasonable,
Bring out the best in each other, play the work(that righting sustains losses in business, is warming lung and reducing phlegm, evacuating fever and chills, inducing meastruation to relieve menalgia, tonifying spleen and stomach altogether, lesion depths of going directly is right
The cause of disease of chronic cor pulmonale is targetedly put in poison, and has reached the effect of clearing heat and detoxicating, antibacterial anti-inflammatory and resolving sputum and relieving asthma
Fruit；At the same time, additionally it is possible to which conditioning inside of human body function comprehensively, has the function that tonifying Qi kidney-nourishing, mends fire supporing yang and antitoxic heart-soothing and sedative, strengthens
The immunity of human body, improves the disease resistance of human body；Treatment for chronic cardiopulmonary disease have it is evident in efficacy, it is quick,
Cure rate is high, and efficacy stability is convenient to take, the characteristics of having no toxic side effect.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on, should all be included in the protection scope of the present invention god.
Claims (4)
- A kind of 1. Chinese medicine composition for treating chronic cardiopulmonary disease, it is characterised in that：It is made of the raw material of following parts by weight：It is 8-12 parts of fruit of negundo, 8-12 parts of moxibustion Chinese ephedra, 8-12 parts of cassia twig, 8-12 parts of radix bupleuri, 8-12 parts of the root of purple-flowered peucedanum, 8-12 parts of the radix paeoniae rubrathe, white 8-12 parts of Chinese herbaceous peony, 8-12 parts of the banksia rose, 8-12 parts of Ligusticum wallichii, 8-12 parts of grass-leaved sweetflag, 8-12 parts of lepidium seed, 8-12 parts of wrinkled giant hyssop, earthworm 8-12 Part, 4-8 parts of asarum, 4-8 parts of wild ginger, 4-8 parts of peppermint, 4-8 parts of rhizoma zingiberis, 4-8 parts of monkshood, 8-12 parts of blackberry lily, 8-12 parts of Folium Elaeagni, 8-12 parts of coltsfoot, 4-8 parts of periostracum cicada, 8-12 parts of dried orange peel, 8-12 parts of the tuber of multiflower knotweed, 8-12 parts of Poria cocos, 4-8 parts of honey-fried licorice root, 8-12 parts of Radix Salviae Miltiorrhizae, 8-12 parts of amethyst.
- 2. the Chinese medicine composition for the treatment of chronic cardiopulmonary disease according to claim 1, it is characterised in that：By following parts by weight Raw material is made：10 parts of fruit of negundo, 10 parts of moxibustion Chinese ephedra, 10 parts of cassia twig, 10 parts of radix bupleuri, 10 parts of the root of purple-flowered peucedanum, 10 parts of the radix paeoniae rubrathe, 10 parts of Radix Paeoniae Alba, It is 10 parts of the banksia rose, 10 parts of Ligusticum wallichii, 10 parts of grass-leaved sweetflag, 10 parts of lepidium seed, 10 parts of wrinkled giant hyssop, 10 parts of earthworm, 6 parts of asarum, 6 parts of wild ginger, thin 6 parts of lotus, 6 parts of rhizoma zingiberis, 6 parts of monkshood, 10 parts of blackberry lily, 10 parts of Folium Elaeagni, 10 parts of coltsfoot, 6 parts of periostracum cicada, 10 parts of dried orange peel, 10 parts of the tuber of multiflower knotweed, 10 parts of Poria cocos, 6 parts of honey-fried licorice root, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of amethyst.
- 3. the Chinese medicine composition for the treatment of chronic cardiopulmonary disease according to claim 1 or 2, it is characterised in that：The Chinese medicine group The formulation of compound is one kind in decoction, pill, granule, capsule or tablet.
- 4. the Chinese medicine composition for the treatment of chronic cardiopulmonary disease according to claim 3, it is characterised in that：The pill is sophora flower Honeyed bolus, is 2g per ball weight.
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