CN113768830A - Skin care composition and preparation method thereof - Google Patents
Skin care composition and preparation method thereof Download PDFInfo
- Publication number
- CN113768830A CN113768830A CN202110803007.7A CN202110803007A CN113768830A CN 113768830 A CN113768830 A CN 113768830A CN 202110803007 A CN202110803007 A CN 202110803007A CN 113768830 A CN113768830 A CN 113768830A
- Authority
- CN
- China
- Prior art keywords
- skin care
- care composition
- skin
- alcohol
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 51
- 238000002360 preparation method Methods 0.000 title description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 28
- 229940106189 ceramide Drugs 0.000 claims abstract description 14
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims abstract description 13
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims abstract description 13
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims abstract description 13
- 125000000623 heterocyclic group Chemical group 0.000 claims abstract description 13
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 11
- 239000003906 humectant Substances 0.000 claims abstract description 11
- 239000000419 plant extract Substances 0.000 claims abstract description 11
- 150000004676 glycans Chemical class 0.000 claims abstract description 10
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 10
- 239000005017 polysaccharide Substances 0.000 claims abstract description 10
- 229920001577 copolymer Polymers 0.000 claims abstract description 8
- 239000002904 solvent Substances 0.000 claims abstract description 8
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 6
- 239000001301 oxygen Substances 0.000 claims abstract description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229920002521 macromolecule Polymers 0.000 claims abstract description 5
- 125000001931 aliphatic group Chemical group 0.000 claims abstract 2
- 150000005846 sugar alcohols Polymers 0.000 claims abstract 2
- 239000000284 extract Substances 0.000 claims description 21
- 229920005862 polyol Polymers 0.000 claims description 20
- DDADCBXAKYGDEH-UHFFFAOYSA-N 2-(3-hydroxypropyl)oxane-2,3,4-triol Chemical compound OCCCC1(O)OCCC(O)C1O DDADCBXAKYGDEH-UHFFFAOYSA-N 0.000 claims description 19
- 150000003077 polyols Chemical class 0.000 claims description 18
- -1 lauryl PEG-10 Chemical compound 0.000 claims description 13
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 10
- BBAFBDLICMHBNU-MFZOPHKMSA-N N-(2-hydroxyoctadecanoyl)-4-hydroxysphinganine Chemical compound CCCCCCCCCCCCCCCCC(O)C(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC BBAFBDLICMHBNU-MFZOPHKMSA-N 0.000 claims description 7
- ATGQXSBKTQANOH-UWVGARPKSA-N N-oleoylphytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC ATGQXSBKTQANOH-UWVGARPKSA-N 0.000 claims description 7
- MIUIRGGKIICMBP-NFOZDHADSA-N [27-oxo-27-[[(2s,3s,4r)-1,3,4-trihydroxyoctadecan-2-yl]amino]heptacosyl] octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC MIUIRGGKIICMBP-NFOZDHADSA-N 0.000 claims description 7
- 229940048864 ceramide 1 Drugs 0.000 claims description 7
- 229940044176 ceramide 3 Drugs 0.000 claims description 7
- 229940095137 ceramide 6 ii Drugs 0.000 claims description 7
- 235000012000 cholesterol Nutrition 0.000 claims description 6
- 241000195493 Cryptophyta Species 0.000 claims description 5
- 241001428166 Eucheuma Species 0.000 claims description 5
- 241000195474 Sargassum Species 0.000 claims description 5
- 235000010418 carrageenan Nutrition 0.000 claims description 4
- 229940074992 chondrus crispus extract Drugs 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 229940020856 fucus serratus extract Drugs 0.000 claims description 4
- 229920000642 polymer Polymers 0.000 claims description 4
- NTYZDAJPNNBYED-UHFFFAOYSA-M sodium;2-(2-dodecanoyloxypropanoyloxy)propanoate Chemical group [Na+].CCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C([O-])=O NTYZDAJPNNBYED-UHFFFAOYSA-M 0.000 claims description 4
- 239000000230 xanthan gum Substances 0.000 claims description 4
- 229920001285 xanthan gum Polymers 0.000 claims description 4
- 235000010493 xanthan gum Nutrition 0.000 claims description 4
- 229940082509 xanthan gum Drugs 0.000 claims description 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 3
- 235000010445 lecithin Nutrition 0.000 claims description 3
- 239000000787 lecithin Substances 0.000 claims description 3
- 229940067606 lecithin Drugs 0.000 claims description 3
- 229940031709 peg-30-dipolyhydroxystearate Drugs 0.000 claims description 3
- 239000007983 Tris buffer Substances 0.000 claims description 2
- 241000607122 Uncaria tomentosa Species 0.000 claims description 2
- 235000011472 cat’s claw Nutrition 0.000 claims description 2
- 241001252601 Blumea Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000003491 skin Anatomy 0.000 abstract description 77
- 230000000694 effects Effects 0.000 abstract description 21
- 230000003020 moisturizing effect Effects 0.000 abstract description 16
- 230000002087 whitening effect Effects 0.000 abstract description 9
- 230000008439 repair process Effects 0.000 abstract description 8
- 239000004615 ingredient Substances 0.000 abstract description 7
- 230000004888 barrier function Effects 0.000 abstract description 6
- 230000003266 anti-allergic effect Effects 0.000 abstract description 3
- 230000008099 melanin synthesis Effects 0.000 abstract description 3
- 210000002752 melanocyte Anatomy 0.000 abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 27
- 238000012360 testing method Methods 0.000 description 24
- 235000013336 milk Nutrition 0.000 description 16
- 239000008267 milk Substances 0.000 description 16
- 210000004080 milk Anatomy 0.000 description 16
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 14
- 230000008859 change Effects 0.000 description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 11
- 210000002966 serum Anatomy 0.000 description 10
- AERBNCYCJBRYDG-UHFFFAOYSA-N D-ribo-phytosphingosine Natural products CCCCCCCCCCCCCCC(O)C(O)C(N)CO AERBNCYCJBRYDG-UHFFFAOYSA-N 0.000 description 6
- 229920002683 Glycosaminoglycan Polymers 0.000 description 6
- 230000003247 decreasing effect Effects 0.000 description 6
- AERBNCYCJBRYDG-KSZLIROESA-N phytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO AERBNCYCJBRYDG-KSZLIROESA-N 0.000 description 6
- 229940033329 phytosphingosine Drugs 0.000 description 6
- 239000008213 purified water Substances 0.000 description 6
- 239000006071 cream Substances 0.000 description 5
- KOGFZZYPPGQZFZ-QVAPDBTGSA-N (2s,3r,4s,5r)-2-(2-hydroxypropyl)oxane-3,4,5-triol Chemical compound CC(O)C[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O KOGFZZYPPGQZFZ-QVAPDBTGSA-N 0.000 description 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 4
- 241001512709 Lessonia <stramenopiles> Species 0.000 description 4
- 230000032683 aging Effects 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- 239000003102 growth factor Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 4
- 239000000049 pigment Substances 0.000 description 4
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 4
- 230000008591 skin barrier function Effects 0.000 description 4
- 239000000600 sorbitol Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- 210000000434 stratum corneum Anatomy 0.000 description 3
- MXNRLFUSFKVQSK-UHFFFAOYSA-N 2-Amino-6-(trimethylazaniumyl)hexanoate Chemical compound C[N+](C)(C)CCCCC(N)C([O-])=O MXNRLFUSFKVQSK-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 101710113758 Basement membrane proteoglycan Proteins 0.000 description 2
- 102100032912 CD44 antigen Human genes 0.000 description 2
- 241000206575 Chondrus crispus Species 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 241000004454 Fucus serratus Species 0.000 description 2
- 241000254191 Harpagophytum procumbens Species 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 description 2
- 241001428258 Hypnea musciformis Species 0.000 description 2
- 208000028990 Skin injury Diseases 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229960001631 carbomer Drugs 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 210000001339 epidermal cell Anatomy 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 230000013632 homeostatic process Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 210000002510 keratinocyte Anatomy 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 2
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 2
- 229960002216 methylparaben Drugs 0.000 description 2
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 2
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 2
- 229960003415 propylparaben Drugs 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 230000037307 sensitive skin Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 description 1
- 235000021513 Cinchona Nutrition 0.000 description 1
- 241000157855 Cinchona Species 0.000 description 1
- 108010067787 Proteoglycans Proteins 0.000 description 1
- 241001262105 Sargassum muticum Species 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003679 aging effect Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001783 ceramides Chemical class 0.000 description 1
- 229940107161 cholesterol Drugs 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229940100524 ethylhexylglycerin Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- LTNJYGRCMNQPFQ-UHFFFAOYSA-M sodium;2-dodecanoyloxypropanoate Chemical compound [Na+].CCCCCCCCCCCC(=O)OC(C)C([O-])=O LTNJYGRCMNQPFQ-UHFFFAOYSA-M 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 210000000216 zygoma Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the field of skin care products, in particular to A61Q 19/08. The skin care composition comprises ceramide, an alcohol humectant, an emulsifier, a carboxyvinyl copolymer, a plant extract, a polysaccharide macromolecular compound and a solvent, wherein the alcohol humectant is selected from one or more of aliphatic polyhydric alcohol, non-heterocyclic alcohol and oxygen-containing heterocyclic alcohol. The skin care composition has excellent barrier repair, deep moisturizing and whitening effects; the composition of the four ingredients in the application has a coordinating effect, and can perform good barrier repair and deep moisturizing on skin. In addition, the four ingredients have skin repairing and antiallergic effects, and simultaneously inhibit melanocyte activity, thereby reducing melanin production and whitening skin.
Description
Technical Field
The invention relates to the field of skin care products, in particular to A61Q 19/08.
Background
With the improvement of living standard and aesthetic consciousness of people, the skin care product industry is developing vigorously, and various skin care products with the functions of moisturizing, whitening, sun screening, resisting oxidation, repairing skin and the like are developed endlessly.
However, the existing skin care products have the disadvantages of excessive added chemical components, easy sensitization, strong irritation caused by the added surfactant, red mark generation and the like, poor moisturizing aging effect, slow melanin disappearance and single effect, and cannot meet the requirements of multiple indexes of current consumers, and CN201510117336 discloses a whitening skin care lotion and a preparation method thereof. Therefore, it is desirable to provide a skin care composition having multiple effects of barrier repair, deep moisturizing, and whitening.
Disclosure of Invention
In view of the problems in the prior art, the first aspect of the present invention provides a skin care composition comprising ceramide, alcohol humectant, emulsifier, carboxyvinyl copolymer, plant extract, polysaccharide polymer compound, and solvent, wherein the alcohol humectant is selected from one or more of aliphatic polyol, non-heterocyclic alcohol, and oxygen-containing heterocyclic alcohol.
As a preferred technical scheme of the invention, the plant extract is selected from one or more of a Chondrus crispus extract, a Harpagophytum procumbens extract, a Eucheuma Gelatinosum extract, a Fucus serratus extract, a Sargassum blumerinum extract and a hydrolyzed algae extract.
As a preferred technical scheme of the invention, the fatty polyol comprises C3-20 fatty polyol.
As a preferred technical scheme of the invention, the fatty polyol comprises (a) C3-6 fatty polyol and (b) C18-20 fatty polyol.
In a preferred embodiment of the present invention, the non-heterocyclic alcohol comprises cholesterol.
In a preferred embodiment of the present invention, the heterocyclic oxygen-containing alcohol comprises hydroxypropyl tetrahydropyrane triol.
In a preferred embodiment of the present invention, the ceramide is selected from one or more of ceramide 1, ceramide 3, and ceramide 6 II.
As a preferred technical scheme of the invention, the emulsifier is selected from one or more of sodium lauroyl lactylate, PEG-30 dipolyhydroxystearate, lecithin and lauryl PEG-10 tris (trimethylsiloxy) silicon ethyl polymethylsiloxane.
In a preferred embodiment of the present invention, the polysaccharide polymer compound includes xanthan gum.
In a second aspect of the present invention, there is provided a method for preparing the skin care composition, comprising: mixing ceramide, alcohol humectant, emulsifier, carboxyvinyl copolymer, plant extract, polysaccharide macromolecular compound, and solvent.
Compared with the prior art, the invention has the following beneficial effects:
(1) the skin care composition has excellent barrier repair, deep moisturizing and whitening effects, and due to the use of glycerin, sorbitol, phytosphingosine, cholesterol and hydroxypropyl tetrahydropyrane triol, the problem of poor softness caused by ceramide 1, ceramide 3 and ceramide 6II is avoided, and the experience feeling is enhanced;
(2) the SK-difluux in the application contains various ceramide and phytosphingosine components, and can directly repair skin barriers; hydroxypropyl tetrahydropyrane triol prevents the decrease and degradation of the in vivo activity of GAGs and PGs, promotes the biosynthesis of mucopolysaccharides and pgproteoglycans of epidermal cells GAGs, to increase the skin's ability to bind water and to improve the skin's ability to biodedefend. The expression of CD44 protein, Syndocations, basement membrane proteoglycan and laminine 5 is increased to improve the cohesion of the epidermis and the dermis-epidermis junction (DEJ), so that the skin is stronger and more elastic. Can directly act on keratinocyte to renew through interaction with growth factors, and directly regulate and control the epidermal homeostasis in the aging process through releasing the growth factors, thereby achieving the effects of effectively improving neck fine lines and preventing aging and achieving the effect of deep moisturizing; FUCOSORB and FUCOREVERSE PF have effects in inhibiting inflammatory factors, improving skin allergy and redness, and repairing skin injury caused by ultraviolet radiation; the composition of the four ingredients in the application has a coordinating effect, and can perform good barrier repair and deep moisturizing on skin. In addition, the four ingredients have skin repairing and antiallergic effects, and simultaneously inhibit melanocyte activity, thereby reducing melanin production and whitening skin.
Drawings
FIG. 1 is a graph of the results of a test of the trans-dermal water loss rate (TEWL) of serum milk obtained using the skin care composition of example 3;
FIG. 2 is a graph showing the results of a stratum corneum moisture content (on the nasal side of the face) test of a serum milk obtained using the skin care composition of example 3;
FIG. 3 is a view of the red area of the VISIA front view of a test subject;
FIG. 4 is a graph showing the results of a melanin value test of the serum milk obtained using the skin care composition of example 3;
fig. 5 is a graph of the ITA ° test results of the serum milk obtained using the skin care composition of example 3.
Detailed Description
The present invention is illustrated by the following specific embodiments, but is not limited to the specific examples given below.
The invention provides a skin care composition, which comprises ceramide, an alcohol humectant, an emulsifier, a carboxyvinyl copolymer, a plant extract, a polysaccharide macromolecular compound and a solvent.
In one embodiment, the skin care composition further comprises a preservative.
In one embodiment, the ceramide is selected from one or more of ceramide 1, ceramide 3, ceramide 6 II.
Preferably, the ceramides include ceramide 1, ceramide 3, and ceramide 6 II.
In one embodiment, the alcoholic humectant is selected from one or more of aliphatic polyols, non-heterocyclic alcohols, and oxygenated heterocyclic alcohols.
Preferably, the fatty polyol comprises a C3-20 fatty polyol.
Further preferably, the fatty polyol comprises (a) a C3-6 fatty polyol and (b) a C18-20 fatty polyol.
Further preferably, the C3-6 fat polyol comprises glycerol and sorbitol.
Further preferably, the C18-20 fatty polyol comprises phytosphingosine.
Preferably, the non-heterocyclic alcohol comprises cholesterol.
Preferably, the oxygenated heterocyclic alcohol comprises hydroxypropyl tetrahydropyrane triol.
The applicant finds that the experience feeling of a user is poor and the softening effect is poor while achieving the moisturizing effect by using the commonly used ceramide 1, ceramide 3 and ceramide 6II, and unexpectedly finds that when the specific alcohol moisturizing agents are used, particularly the alcohol moisturizing agents comprise fatty polyol, non-heterocyclic alcohol and oxygen-containing heterocyclic alcohol, and are respectively glycerol, sorbitol, phytosphingosine, cholesterol and hydroxypropyl tetrahydropyrane triol, the skin flexibility is good at the moment, the generation of the poor experience feeling is avoided, the applicant considers that the possible reason is the alcohols of different specific fatty chain segments in the application, when the specific alcohol moisturizing agents are acted on the skin and are associated with water molecules, the distribution of a network structure formed by the ceramide is changed, meanwhile, the specific alcohol moisturizing agents transport the water molecules in time, and the permeability and the flexibility of the skin are increased.
In one embodiment, the emulsifier is selected from one or more of sodium lauroyl lactylate, PEG-30 dipolyhydroxystearate, lecithin, lauryl PEG-10 tris (trimethylsiloxy) silylethyl methicone.
Preferably, the emulsifier comprises sodium lauroyl lactylate.
In one embodiment, the carboxyvinyl copolymer comprises carbomer.
In one embodiment, the plant extract is selected from one or more of Chondrus crispus extract, Uncaria tomentosa extract, Eucheuma muricatum extract, Fucus serratus extract, Sargassum blumerinum extract, and hydrolyzed algae extract.
Preferably, the plant extract includes Chondrus crispus extract, Harpagophytum procumbens extract, Eucheuma Gelatinosum extract, Fucus serratus extract, Sargassum blunt, and hydrolyzed algae extract.
In one embodiment, the polysaccharide polymer compound comprises xanthan gum.
In one embodiment, the solvent is water.
The preservative described herein is not particularly limited and may be routinely selected by those skilled in the art.
In one embodiment, the preservative is selected from one or more of phenoxyethanol, ethylhexylglycerin, methylparaben, and propylparaben.
The proportions of the ingredients in the skin care compositions herein are not particularly limited and can be routinely selected by those skilled in the art.
In a second aspect of the present invention, there is provided a method for preparing the skin care composition, comprising: mixing ceramide, alcohol humectant, emulsifier, carboxyvinyl copolymer, plant extract, polysaccharide macromolecular compound, and solvent.
In one embodiment, the skin care composition comprises, by weight, 0.1 to 10 parts SK-influx V, 0.1 to 10 parts hydroxypropyl tetrahydropyrane triol, 0.1 to 15 parts FUCOSORB, 0.1 to 10 parts FUCOREVEREPF.
Preferably, the skin care composition comprises 5 parts by weight of SK-influx V, 6 parts by weight of hydroxypropyl tetrahydropyrane triol, 8 parts by weight of FUCOSORB and 5 parts by weight of FUCOREVERSE PF.
SK-influx V is purchased from Yongchu specialty Chemicals (Shanghai) Co., Ltd in the present application, and comprises ceramide 3, ceramide 6II, ceramide 1, phytosphingosine, cholesterol, sodium lauroyl lactate, carbomer, xanthan gum and water.
Hydroxypropyl tetrahydropyran triol is purchased from yokehui sies biotechnology limited, incorporated herein.
FUCOSORB is available from Cinchonas sempervirens pigment technology (China) Co., Ltd, and comprises sorbitol, Chondrus CRISPUS (Chondrus CRISPUS) extract, Hypnea MUSCIFORMIS (Hypnea MUSCIFORMIS) extract, Eucheuma Gelatinosum (GELLIDIELA ACEROSA) extract, Fucus SERRATUS (Fucus SERRATUS) extract, Sargassum (Sargassum MUTICUM) extract, methylparaben, propylparaben, and water.
Fucoreverse PF is obtained from Lessonia, France, and comprises glycerol, water, and hydrolyzed algae extract.
In one embodiment, the skin care composition is prepared by a method comprising: mixing SK-influx, hydroxypropyl tetrahydropyrane triol, FUCOSORB and FUCOREVERSE PF.
SK-influx contains various ceramide and phytosphingosine components in the application, and can directly repair skin barrier.
The hydroxypropyl tetrahydropyrane triol in the application prevents the reduction and degradation of the in vivo activity of the GAGs and PGs, and promotes the biosynthesis of epidermal cell GAGs mucopolysaccharide and PG proteoglycan so as to increase the skin water binding capacity and improve the skin biological defense capacity. The expression of CD44 protein, Syndocations, basement membrane proteoglycan and laminine 5 is increased to improve the cohesion of the epidermis and the dermis-epidermis junction (DEJ), so that the skin is stronger and more elastic. Can directly act on keratinocyte to renew through interaction with growth factors, and directly regulate and control the epidermal homeostasis in the aging process through releasing the growth factors, thereby achieving the effects of effectively improving neck fine lines and preventing aging and achieving the effect of deep moisturizing.
FUCOSORB and FUCOREVERSE PF have the effects of inhibiting inflammatory factors, improving skin allergy and redness, and repairing skin injury caused by ultraviolet irradiation.
The composition of the four ingredients in the application has a coordinating effect, and can perform good barrier repair and deep moisturizing on skin. In addition, the four ingredients have skin repairing and antiallergic effects, and simultaneously inhibit melanocyte activity, thereby reducing melanin production and whitening skin.
Examples
Hereinafter, the present invention will be described in more detail by way of examples, but it should be understood that these examples are merely illustrative and not restrictive. The starting materials used in the examples which follow are all commercially available unless otherwise stated.
Example 1
Embodiment 1 of the present invention provides a skin care composition, which comprises the following components in parts by weight: 1 part of SK-influx V, 0.1 part of hydroxypropyl tetrahydropyrane triol, 0.1 part of FUCOSORB and 0.1 part of FUCOREVERSE PF.
The SK-infilux V was purchased from the creative Special chemistry (Shanghai) Co., Ltd.
The hydroxypropyl tetrahydropyran triol is purchased from yagi biotechnology limited.
The FUCOSORB is available from Sendzein pigment technology (China) Inc.
The FUCOREVERSE PF is available from Lessonia, France.
The preparation method of the skin care composition comprises the following steps: mixing SK-influx, hydroxypropyl tetrahydropyrane triol, FUCOSORB and FUCOREVERSE PF.
Example 2
Embodiment 2 of the present invention provides a skin care composition, which comprises the following components in parts by weight: 10 parts of SK-influx V, 10 parts of hydroxypropyl tetrahydropyrane triol, 15 parts of FUCOSORB and 10 parts of FUCOREVERSE PF.
The SK-infilux V was purchased from the creative Special chemistry (Shanghai) Co., Ltd.
The hydroxypropyl tetrahydropyran triol is purchased from yagi biotechnology limited.
The FUCOSORB is available from Sendzein pigment technology (China) Inc.
The FUCOREVERSE PF is available from Lessonia, France.
The preparation method of the skin care composition comprises the following steps: mixing SK-influx, hydroxypropyl tetrahydropyrane triol, FUCOSORB and FUCOREVERSE PF.
Example 3
Embodiment 3 of the present invention provides a skin care composition, which comprises the following components in parts by weight: 5 parts of SK-influx V, 6 parts of hydroxypropyl tetrahydropyrane triol, 10 parts of FUCOSORB and 1 part of FUCOREVERSE PF.
The SK-infilux V was purchased from the creative Special chemistry (Shanghai) Co., Ltd.
The hydroxypropyl tetrahydropyran triol is purchased from yagi biotechnology limited.
The FUCOSORB is available from Sendzein pigment technology (China) Inc.
The FUCOREVERSE PF is available from Lessonia, France.
The preparation method of the skin care composition comprises the following steps: mixing SK-influx, hydroxypropyl tetrahydropyrane triol, FUCOSORB and FUCOREVERSE PF.
Example 4
Example 4 of the present application provides a skin care composition, which is the same as example 3, except that the hydroxypropyl tetrahydropyrane triol is 0 part by weight.
The skin care composition is prepared by mixing SK-influx, FUCOSORB and FUCOREVERSE PF.
Example 5
Example 5 of the present application provides a skin care composition, which is embodied in the same manner as example 3 except that SK-biflux V is used in an amount of 0 parts by weight.
The skin care composition is prepared by mixing hydroxypropyl tetrahydropyrane triol, FUCOSORB and FUCOREVERSE PF.
Example 6
Example 6 of the present application provides a skin care composition, which is embodied in the same manner as in example 3, except that FUCOSORB is present in an amount of 0 parts by weight.
The skin care composition is prepared by mixing SK-influx, hydroxypropyl tetrahydropyrane triol, and FUCOREVERSE PF.
Performance evaluation
The skin care compositions obtained in examples 1 to 6 were each diluted to 20 wt% of serum milk using water, and subjected to the following relevant tests.
And (3) testing time: 2020.09.22
The test purpose is as follows: moisture retention, comfort test
Testing indexes are as follows: TEWL, water content of stratum corneum, red zone
The environment tested at that time: humidity RH is 40-60%, temperature T is 20-22 deg.C
Testing parts: left and right face (cheekbone side, nose wing side)
The number of tested persons: 10 persons (including normal skin and sensitive skin)
The test requirements are as follows: cleaning and disinfecting the probe with a clean towel before measurement, and completely drying the probe before measurement; cleaning the part and then wiping the part with a soft towel; the testee is quiet for 30min before measurement; the change of the transdermal water loss rate with time during the violent exercise is avoided in the test process. Purified water or blank was used as a control.
Instruments and test articles:
MSC1275 MoistrureMeterSC cuticle moisture content measuring instrument
SWL5372Vapometer percutaneous water loss measuring instrument
VISIA 7.0 facial skin imaging analyzer
DCC1095 SkinColorcatch skin color measuring instrument
1. Moisture retention test:
the results of the test of the trans-dermal water loss rate (TEWL) of the serum obtained using the skin care composition of example 3 are shown in fig. 1.
The transdermal water loss rate (TEWL), which represents the rapid and slow rate of water loss of the skin, is related to the skin barrier, and the smaller the value, the better the skin barrier and the stronger the water-locking capacity of the skin.
From the test results, the TEWL values decreased first and then increased after the essential milk and the purified water were used, that is, the skin water loss rate was decreased, the TEWL value measured for 0.5h of the essential milk reached the peak value, the maximum change percentage was-56.89%, and the change percentage was-43.666% in 2h, while the maximum change percentage was-7.10% in 0.5h of the purified water, and the change percentage was 24.49% in 2 h. In conclusion, the essential milk has a good skin water locking effect compared with purified water.
The results of the stratum corneum moisture content (on the nasal side of the face) test of the serum obtained using the skin care composition of example 3 are shown in fig. 2.
From the test results, after the essence milk is used, the water content value of the horny layer is increased firstly and then decreased, namely the water content of the horny layer is increased firstly and then decreased, the water content value of the horny layer measured by the essence milk in 0.25h (namely 15min) reaches the peak value, the maximum change percentage of the essence milk in 2h is 54.87%, the change percentage in 2h is 45.40%, the maximum change percentage of purified water is 17.39%, and the change percentage in 2h is 16.68%, and the essence milk is obviously superior to the purified water and has relatively good moisturizing effect.
The values of the red area on the VISIA front view of the serum obtained using the skin care composition of example 3 vary as shown in table 1.
TABLE 1
| Index (I) | Blank control | After smearing | Percent change |
| Percentile | 68％ | 71.4％ | 5.00％ |
| Feature counting | 13.2 | 12.6 | -4.55％ |
| Score value | 8.95 | 8.61 | -3.80％ |
Note that:
the percentile: describe skin feature scores compared to others of the same age, same gender, same skin type (higher values are better)
Secondly, score value: reflecting the size, area and density of the features (lower number is better)
Thirdly, counting the characteristics: representing the number of individual skin features detected within the facial mask area (lower values are better)
(iv) percent change ═ value after application-blank value)/blank value
As can be seen from Table 1, the percentage change of the percentile is 5.00%, which is improved compared with the blank after the essence cream is used. The percent change in feature counts was-4.55%, i.e., the skin feature count was reduced. The percentage of change in the score was-3.80%, indicating that hemoglobin was improved by combining the characteristics of size, area, and density. Has slight relieving effect on sensitive skin, and slightly improves hemoglobin.
The VISIA front view red area of one of the testers is shown in fig. 3.
2. Melanin value and ITA ° test:
a melanin value, representing the melanin concentration of the skin, the greater the value, the darker the skin;
ITA °, represents the shade scale of skin color from black to white, and the larger the value, the more whitish the value.
The results of the melanin value test of the serum milk obtained using the skin care composition of example 3 are shown in fig. 4.
From fig. 4, it can be seen that the melanin value rapidly decreased after 1 week of the use of the essence milk, and decreased to 620 or less after 28 days of the use.
The ITA ° test results of the serum milk obtained using the skin care composition of example 3 are shown in fig. 5.
As can be seen from fig. 5, the whitening effect was significant after 1 month of using the essence cream.
The use feeling test: the above 10 tested persons apply the essence creams obtained from the skin care compositions of examples 1 to 6 to the cheek parts respectively, and the using effects of the essence creams are comprehensively scored on the aspects of the difficulty of applying the essence creams, the stimulation degree of the skin, the absorption speed of the skin, the obvious degree of softening the skin and the like. The comprehensive score range is 1-10 points, 1 point is very unsatisfactory, 10 points are very satisfactory, and the higher the score is, the higher the satisfaction degree of the tester on the using effect of the essence milk is. The number of people with the comprehensive score of 6-10 is counted in the test, and the result is shown in table 2.
TABLE 2
Claims (10)
1. A skin care composition is characterized by comprising ceramide, an alcohol humectant, an emulsifier, a carboxyvinyl copolymer, a plant extract, a polysaccharide high molecular compound and a solvent, wherein the alcohol humectant is selected from one or more of aliphatic polyhydric alcohol, non-heterocyclic alcohol and oxygen-containing heterocyclic alcohol.
2. The skin care composition of claim 1, wherein the plant extract is selected from one or more of Chondrus crispus extract, Uncaria tomentosa extract, Eucheuma muricatum extract, Fucus serratus extract, Sargassum blumea extract, and hydrolyzed algae extract.
3. The skin care composition of claim 1, wherein the fatty polyol comprises a C3-20 fatty polyol.
4. The skin care composition of claim 3, wherein the fatty polyol comprises (a) a C3-6 fatty polyol and (b) a C18-20 fatty polyol.
5. A skin care composition according to any of claims 1 to 4 wherein said non-heterocyclic alcohol comprises cholesterol.
6. The skin care composition of claim 5 wherein the oxygen heterocycle-containing alcohol comprises hydroxypropyl tetrahydropyrane triol.
7. The skin care composition according to claim 6, wherein the ceramide is selected from one or more of ceramide 1, ceramide 3, and ceramide 6 II.
8. The skin care composition of claim 1 wherein the emulsifier is selected from the group consisting of sodium lauroyl lactylate, PEG-30 dipolyhydroxystearate, lecithin, lauryl PEG-10 tris (trimethylsiloxy) silylethyl methicone.
9. A skin care composition according to any one of claims 6 to 8 wherein said polysaccharide polymer comprises xanthan gum.
10. A method of making a skin care composition according to any one of claims 1-9 comprising: mixing ceramide, alcohol humectant, emulsifier, carboxyvinyl copolymer, plant extract, polysaccharide macromolecular compound, and solvent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110803007.7A CN113768830A (en) | 2021-07-15 | 2021-07-15 | Skin care composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110803007.7A CN113768830A (en) | 2021-07-15 | 2021-07-15 | Skin care composition and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113768830A true CN113768830A (en) | 2021-12-10 |
Family
ID=78835916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110803007.7A Pending CN113768830A (en) | 2021-07-15 | 2021-07-15 | Skin care composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113768830A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983886A (en) * | 2022-05-27 | 2022-09-02 | 广东嘉丹婷日用品有限公司 | Anti-allergy soothing composition with skin barrier repair effect |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010047493A (en) * | 2008-08-19 | 2010-03-04 | Septem Soken:Kk | Microcapsule and skin external preparation containing the same |
| CN112043668A (en) * | 2020-09-16 | 2020-12-08 | 上海百好博生物科技有限公司 | Composition with functions of moisturizing and repairing skin barrier and application |
-
2021
- 2021-07-15 CN CN202110803007.7A patent/CN113768830A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010047493A (en) * | 2008-08-19 | 2010-03-04 | Septem Soken:Kk | Microcapsule and skin external preparation containing the same |
| CN112043668A (en) * | 2020-09-16 | 2020-12-08 | 上海百好博生物科技有限公司 | Composition with functions of moisturizing and repairing skin barrier and application |
Non-Patent Citations (1)
| Title |
|---|
| 德国蓓施化妆品有限公司: "《进口普通化妆品备案信息》", 25 April 2021 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983886A (en) * | 2022-05-27 | 2022-09-02 | 广东嘉丹婷日用品有限公司 | Anti-allergy soothing composition with skin barrier repair effect |
| CN114983886B (en) * | 2022-05-27 | 2024-04-19 | 广东嘉丹婷日用品有限公司 | Anti-allergic and soothing composition with skin barrier repair effect |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110302101B (en) | Moisturizing repair emulsion and preparation method thereof | |
| CN111789777A (en) | Skin care cream with immediate tightening and anti-aging effects and preparation method thereof | |
| CN111840161A (en) | Anti-aging brightening composition and application and preparation method thereof | |
| CN111920728A (en) | Cosmetic relieving and repairing composition and cosmetic | |
| CN110974758A (en) | Moisture mask and preparation method thereof | |
| CN111150681A (en) | Moisturizing compound containing symbiotic bacteria combined fermentation product, moisturizing essence and preparation method of moisturizing compound | |
| CN113398016A (en) | Skin soothing and repairing composition and cosmetic composition | |
| CN113786379A (en) | Lactic acid bacteria whitening and repairing essence and preparation method thereof | |
| CN111467271A (en) | Skin care product containing acetylated hyaluronic acid | |
| CN107802538B (en) | Anti-aging composition and cosmetic containing same | |
| CN110115691B (en) | Whitening and skin-tendering emulsion containing rice fermentation product and preparation method thereof | |
| CN110279594A (en) | A kind of intensive moisturizing sodium hyaluronate stoste of multiple maintenance and preparation method thereof | |
| CN114306165B (en) | Moisturizing composition and preparation method thereof | |
| CN112402345A (en) | Deep moisturizing composition, cosmetics and preparation method thereof | |
| CN116889520A (en) | Moisturizing repair composition, double collagen texture repair secondary polishing essence, and preparation method and application thereof | |
| CN111643427A (en) | Anti-aging composition, anti-aging cosmetic and preparation method thereof | |
| CN113768830A (en) | Skin care composition and preparation method thereof | |
| CN113384497B (en) | Composition and cosmetic for double moisturizing, repairing and improving skin elasticity | |
| CN111449985A (en) | Fine moistening and repairing wash-free mask and preparation method thereof | |
| CN111265454B (en) | Moisture-preserving and water-replenishing anti-aging cosmetic composition | |
| CN112263493B (en) | Sunscreen composition, sunscreen gel containing sunscreen composition and preparation method of sunscreen gel | |
| CN117243844A (en) | Collagen-containing skin care product essence and preparation method and application thereof | |
| CN112274456A (en) | Multiple moisturizing composition and application thereof | |
| CN115040463A (en) | Anti-wrinkle whitening composition | |
| CN112807271A (en) | Moisturizing composition, essence and preparation method of moisturizing composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211210 |