CN113712836A - Anti-inflammatory acne-removing skin care composition and preparation method and using method thereof - Google Patents
Anti-inflammatory acne-removing skin care composition and preparation method and using method thereof Download PDFInfo
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- CN113712836A CN113712836A CN202011629478.2A CN202011629478A CN113712836A CN 113712836 A CN113712836 A CN 113712836A CN 202011629478 A CN202011629478 A CN 202011629478A CN 113712836 A CN113712836 A CN 113712836A
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- care composition
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- skin care
- inflammatory acne
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Abstract
The application belongs to the technical field of skin care products, and particularly relates to an anti-inflammatory acne-removing skin care composition and a preparation method and a using method thereof. The anti-inflammatory acne-removing skin care composition comprises the following components in percentage by mass of 100 percent: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; in the anti-inflammatory acne-removing skin care composition, the aqueous phase comprises: 0.1-2% of salicylic acid, 0-6% of fruit acid, 0-10% of a skin conditioner, 0.1-1% of a preservative and the balance of water; in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 0.1-10% of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0-2.9% of other grease. The anti-inflammatory acne-removing skin care composition has the effects of resisting inflammation and removing acnes through the synergistic effect of the components in the oil phase and the water phase, is mild in skin effect and small in irritation, and is capable of softening and moisturizing the skin, protecting skin barriers and avoiding the formation of oily sensitive skin.
Description
Technical Field
The application belongs to the technical field of skin care products, and particularly relates to an anti-inflammatory acne-removing skin care composition and a preparation method and a using method thereof.
Background
The acne muscle has become one of the major skin problems of young adolescents, boys and even adults. The formation of the varicella muscle can be mainly attributed to several aspects: on the other hand, excessive sebum secretion from sebaceous glands, excessive keratinization of hair follicles, and the like cause clogging of pores, resulting in closed comedones. On the other hand, the propionibacterium acnes is excessively propagated, the balance of flora on the skin surface is broken, and acne is generated. The hyperproliferating propionibacterium acnes secretes lipid enzymes, breaking down lipids on the skin surface to produce fatty acids, causing more inflammatory reactions. In yet another aspect, unsaturated oils in sebum, such as squalene, are peroxidized by ultraviolet radiation, further generating active oxygen, exacerbating the inflammatory response associated with acne.
The salicylic acid can permeate pores along with sebaceous glands, dissolve cutin accumulated in the pores and clean the pores. Meanwhile, salicylic acid can also sterilize and diminish inflammation, so salicylic acid is often selected as an effective component for treating the skin problems related to the acne muscles such as comedo and acne. However, salicylic acid has relatively low molecular weight and good skin-friendly properties, so that it has relatively high skin permeability, and chronic or repeated skin contact with salicylic acid can cause dermatitis and even burns. The Chinese food drug administration has a clear regulatory upper limit on the addition of salicylic acid in cosmetics, and the addition of salicylic acid in cosmetics does not exceed 2 wt%. Nevertheless, consumers who use salicylic acid for a long time are still prone to skin sensitive reactions, even oil sensitive muscles. Therefore, how to make the acne skin care product containing salicylic acid milder and prevent the acne muscle consumers from transforming into oil-sensitive muscles is one of the difficulties and the key points of the development of salicylic acid products.
Disclosure of Invention
The application aims to provide an anti-inflammatory acne-removing skin care composition, and a preparation method and a using method thereof, and aims to solve the problem that an existing care product containing salicylic acid is large in skin irritation and easy to generate skin sensitive reaction, so that a acne muscle consumer is changed into an oil sensitive muscle to a certain extent.
In order to achieve the purpose of the application, the technical scheme adopted by the application is as follows:
in a first aspect, the present application provides an anti-inflammatory acne-removing skin care composition, comprising, based on 100% of the total mass of the anti-inflammatory acne-removing skin care composition: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; wherein the content of the first and second substances,
in the anti-inflammatory acne-removing skin care composition, the aqueous phase comprises: 0.1-2% of salicylic acid, 0-6% of fruit acid, 0-10% of a skin conditioner, 0.1-1% of a preservative and the balance of water;
in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 0.1-10% of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0-2.9% of other grease.
In a second aspect, the present application provides a method for preparing an anti-inflammatory and anti-acne skin care composition, comprising:
mixing a heat-insensitive skin conditioner with water, and adding salicylic acid for dissolving and mixing at 50-60 ℃ to obtain a first mixed solution;
cooling the first mixed solution, adding a heat-sensitive skin conditioner and tartaric acid, mixing and dissolving, and adding a preservative to obtain a water phase;
after omega-3 unsaturated fatty acid, omega-6 unsaturated fatty acid and omega-9 unsaturated fatty acid are obtained, mixing the obtained product with other grease to obtain an oil phase;
and mixing the oil phase and the water phase to obtain the anti-inflammatory acne-removing skin care composition.
In a third aspect, the application provides a use method of the anti-inflammatory acne-removing skin care composition, wherein after the anti-inflammatory acne-removing skin care composition is obtained, the anti-inflammatory acne-removing skin care composition is shaken until the anti-inflammatory acne-removing skin care composition is in an emulsion state and then used.
According to the anti-inflammatory acne-removing skin care composition provided by the first aspect of the application, 0.1% -2% of salicylic acid in the water phase component can permeate pores, dissolve cutin accumulated in the pores, clean the pores, play a role in sterilization and inflammation diminishing, and can effectively treat the skin problem of acne skin; 0-6% of fruit acid can accelerate the peeling of skin cutin and enhance the acne removing effect of salicylic acid; the skin conditioner in an amount of 0-10% can regulate skin feel and increase the nursing effect of the composition; 0.1-1% of preservative can prevent the microbial contamination of the composition during production and use, and improve the storage and use stability of the composition. The oil phase component can form a hydrophobic film on the surface of the skin, inhibit the loss of water, prevent the skin from drying and cracking, and play roles of moistening, moisturizing, smoothing and the like, wherein 0.1-10% of omega-3, omega-6 and omega-9 unsaturated fatty acid can relieve the secretion of inflammatory factors caused by the nerve stimulation of salicylic acid and fruit acid, inhibit the conduction of the inflammatory factors, protect squalene in sebum from being oxidized, promote the repair of skin inflammation damage and reduce adverse reactions brought by the environment to skin inflammation; meanwhile, the skin-care product has the effects of softening skin, sealing and moisturizing. And other oil in an oil phase of 0-2.9 percent can further improve the sealing and moisturizing effects of the composition and improve the use skin feel of the composition.
According to the preparation method of the anti-inflammatory acne-removing skin care composition provided by the second aspect of the application, after the raw material components are obtained according to the formula amount, firstly, a heat-insensitive skin conditioner is mixed with water, and then the mixture is heated and added with salicylic acid for dissolving; and then, cooling the first mixed solution, adding a heat-sensitive skin conditioner and fruit acid, mixing and dissolving, and finally adding a preservative for dissolving to obtain a water phase. In addition, omega-3 polyunsaturated fatty acid, omega-6 polyunsaturated fatty acid, omega-9 unsaturated fatty acid and other oil are mixed to obtain oil phase. And mixing the water phase and the oil phase to obtain the anti-inflammatory acne-removing skin care composition. The preparation method of the anti-inflammatory acne-removing skin care composition is simple in process, easy to operate, low in preparation cost and convenient for industrial large-scale production and application.
According to the application method of the anti-inflammatory acne-removing skin care composition provided by the third aspect of the application, after the anti-inflammatory acne-removing skin care composition is obtained, the oil-phase component and the water-phase component of the composition can be separated in a standing state, so that the anti-inflammatory acne-removing skin care composition needs to be shaken to be in an oil-in-water emulsion state before being used and then is applied to the surface of the skin.
Detailed Description
In order to make the technical problems, technical solutions and advantageous effects to be solved by the present application more clearly apparent, the present application is further described in detail below with reference to the embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
In the present invention, the term "and/or" describes the association relationship of the associated objects, and means that there may be three relationships, for example, a and/or B, which may mean: a is present alone, A and B are present simultaneously, and B is present alone. Wherein A and B can be singular or plural. The character "/" generally indicates that the former and latter associated objects are in an "or" relationship.
In the present invention, "at least one" means one or more, "a plurality" means two or more. "at least one of the following" or similar expressions refer to any combination of these items, including any combination of the singular or plural items. For example, "at least one (one) of a, b, or c," or "at least one (one) of a, b, and c," may each represent: a, b, c, a-b (i.e., a and b), a-c, b-c, or a-b-c, wherein a, b, and c may be single or plural, respectively.
It should be understood that, in various embodiments of the present invention, the sequence numbers of the above-mentioned processes do not mean the execution sequence, some or all of the steps may be executed in parallel or executed sequentially, and the execution sequence of each process should be determined by its function and inherent logic, and should not constitute any limitation to the implementation process of the embodiments of the present invention.
The terminology used in the embodiments of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in the examples of the invention and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
The weight of the related components mentioned in the description of the embodiments of the present invention may not only refer to the specific content of each component, but also represent the proportional relationship of the weight among the components, and therefore, the content of the related components is scaled up or down within the scope disclosed in the description of the embodiments of the present invention as long as it is in accordance with the description of the embodiments of the present invention. Specifically, the mass in the description of the embodiments of the present invention may be a mass unit known in the chemical industry field such as μ g, mg, g, kg, etc.
The terms "first" and "second" are used for descriptive purposes only and are used for distinguishing purposes such as substances from one another, and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. For example, a first XX may also be referred to as a second XX, and similarly, a second XX may also be referred to as a first XX, without departing from the scope of embodiments of the invention. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature.
In a first aspect, the embodiments of the present application provide an anti-inflammatory acne-removing skin care composition, which includes, by taking the total mass of the anti-inflammatory acne-removing skin care composition as 100%: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; wherein the content of the first and second substances,
in the anti-inflammatory acne removing skin care composition, the water phase comprises: 0.1-2% of salicylic acid, 0-6% of fruit acid, 0-10% of a skin conditioner, 0.1-1% of a preservative and the balance of water;
in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 0.1-10% of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0-2.9% of other grease.
The anti-inflammatory acne-removing skin care composition provided by the first aspect of the application comprises 3% -10% of oil phase and 90% -97% of water phase, and 0.1% -2% of salicylic acid in the water phase can permeate pores, dissolve cutin accumulated in the pores, clear the pores, play a role in sterilization and inflammation diminishing, and effectively treat the skin problem of acne skin; 0-6% of fruit acid can accelerate the peeling of skin cutin and enhance the acne removing effect of salicylic acid; the skin conditioner in an amount of 0-10% can regulate skin feel and increase the nursing effect of the composition; 0.1-1% of preservative can prevent the microbial contamination of the composition during production and use, and improve the storage and use stability of the composition. The oil phase component can form a hydrophobic film on the surface of the skin, inhibit the loss of water, prevent the skin from drying and cracking, and play roles of moistening, moisturizing, smoothing and the like, wherein 0.1-10% of the mixture of omega-3, omega-6 and omega-9 unsaturated fatty acid can relieve the secretion of inflammatory factors caused by the nerve stimulation of salicylic acid and fruit acid, inhibit the conduction of the inflammatory factors, protect squalene in sebum from being oxidized, promote the repair of skin inflammation injury and reduce adverse reactions brought by the environment to skin inflammation; meanwhile, the skin-care product has the effects of softening skin, sealing and moisturizing. And other oil in an oil phase of 0-2.9 percent can further improve the sealing and moisturizing effects of the composition and improve the use skin feel of the composition. The anti-inflammatory acne-removing skin care composition provided by the embodiment of the application has the effects of resisting inflammation and removing acne through the synergistic interaction of the components in the oil phase and the water phase, is mild in skin effect, small in irritation, capable of softening and moisturizing the skin, capable of protecting skin barriers and capable of avoiding the formation of oily sensitive skin.
In the anti-inflammatory acne-removing skin care composition provided by the embodiment of the application, the percentage contents of the raw material components have the optimal synergistic effect, so that the composition has the optimal anti-inflammatory acne-removing effect, has the optimal inhibition effect on acne-related inflammation, and simultaneously mildly nourishes the skin, inhibits the stimulation effect of salicylic acid and prevents the formation of oil-sensitive muscles.
In some preferred embodiments, the anti-inflammatory acne-removing skin care composition comprises, based on 100% of the total mass of the composition: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; wherein the content of the first and second substances,
in the anti-inflammatory acne removing skin care composition, the water phase comprises: 0.1-2% of salicylic acid, 1-6% of fruit acid, 1-10% of a skin conditioner, 0.1-1% of a preservative and the balance of water; preferably, the water is deionized water;
in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 1 to 9.5 percent of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0.5 to 2 percent of other grease.
The anti-inflammatory and anti-acne skin care compositions of the examples further define minimum levels of skin conditioning agents, fruit acids, omega-3, omega-6 and omega-9 unsaturated fatty acids and other oils. Thereby further ensuring the skin feeling regulating effect of the skin conditioner on the anti-inflammation and anti-acne skin care composition, and simultaneously improving the efficacy diversity of the composition by adding components such as whitening, anti-wrinkle and the like. Further ensuring the synergistic acne removing effect of the fruit acid and the salicylic acid. Further ensuring the effects of relieving, inhibiting inflammation, repairing injury, softening skin, sealing and moisturizing omega-3, omega-6 and omega-9 unsaturated fatty acid, and the like. Further ensuring the effects of resisting inflammation, removing acnes, softening skin, moisturizing and the like of the anti-inflammation and acne-removing skin care composition.
In some embodiments, an Omega-3 (also known as Omega-3) polyunsaturated fatty acid is a fatty acid having one carbon-carbon double bond at the third carbon atom of the methyl terminus of the carbon chain, including: at least one of alpha-linolenic acid, eicosapentaenoic acid and docosahexaenoic acid. The omega-3 polyunsaturated fatty acids used in the embodiments of the present application can strengthen the delicate cell membranes surrounding each cell, provide sufficient nourishment to the cells, and effectively remove intracellular waste. Meanwhile, the skin can secrete stronger collagen and elastic fibers, help to eliminate wrinkles and fine lines and keep the skin stiff and gradually loose. Omega-3 polyunsaturated fatty acids are able to moisturize the skin and maintain health.
In some embodiments, an Omega-6 (also known as Omega-6) polyunsaturated fatty acid is a fatty acid having one carbon-carbon double bond at the sixth carbon atom of the methyl terminus of the carbon chain, including: at least one of linoleic acid, gamma-linoleic acid, conjugated linoleic acid and arachidonic acid. The omega-6 polyunsaturated fatty acids adopted in the embodiment of the application are beneficial to metabolism of sebaceous glands, relieve skin allergy and eczema, prevent skin dryness and water deficiency and keep skin healthy.
In some embodiments, an Omega-9 (also known as Omega-9) unsaturated fatty acid having a carbon-carbon double bond at the ninth carbon atom of the methyl terminus of the carbon chain comprises: at least one of oleic acid, erucic acid and nervonic acid. The omega-9 unsaturated fatty acids adopted in the embodiment of the application can enable the antioxidant vitamin E to more effectively protect cells from being damaged by free radicals, thereby keeping the health and the vitality of the skin.
In some embodiments, the total amount of polyunsaturated fatty acids is 100%, including:
26 to 36 percent of omega-3 unsaturated fatty acid,
34 to 45 percent of omega-6 unsaturated fatty acid,
19 to 32 percent of omega-9 unsaturated fatty acid.
In the anti-inflammatory acne-removing skin care composition provided by the embodiment of the application, the polyunsaturated fatty acids in the proportion can inhibit the action of nitric oxide synthase, reduce the synthesis of skin inflammatory factors nitric oxide and achieve the effects of inhibiting tissue damage and further aggravation of inflammation caused by macrophage stimulated by immune factors, so that the anti-acne related inflammatory reaction is achieved on the skin, and meanwhile, the effects of softening the skin and keeping the skin moist are achieved. On the other hand, the omega-3, omega-6 and omega-9 unsaturated fatty acids are unsaturated oils and fats, and can protect squalene in sebum from oxidation and reduce irritation of salicylic acid. In addition, omega-3, omega-6 and omega-9 unsaturated fatty acids also have anti-inflammatory effects and can be used as adjuvant to salicylic acid for the treatment of acne.
In the anti-inflammatory acne-removing skin care composition in the embodiment of the application, the omega-3, omega-6 and omega-9 unsaturated fatty acids can be obtained by respectively extracting the omega-3 unsaturated fatty acid, the omega-6 unsaturated fatty acid and the omega-9 unsaturated fatty acid from natural vegetable oil, mixing the obtained mixture with other oil to form an oil phase, and mixing the oil phase with a water phase to obtain the anti-inflammatory acne-removing skin care composition. In addition, the mixture of omega-3, omega-6 and omega-9 unsaturated fatty acids can also be directly extracted from natural oil such as cranberry seed oil and macadamia nut oil. In some embodiments, natural oil and fat such as cranberry seed oil and macadamia nut oil which simultaneously contain three components of omega-3, omega-6 and omega-9 unsaturated fatty acids can be directly mixed with other oil and fat to form an oil phase, and then the oil phase is mixed with water to obtain the oil phase of the anti-inflammatory acne-removing skin care composition.
In some embodiments, other greases include: at least one of isopropyl myristate, isopropyl palmitate, isononyl isononanoate, squalane, ethylhexyl isopalmitate, ethylhexyl palmitate, caprylic/capric triglyceride, hydrogenated polyisobutene, and hydrogenated polydecene. The other oils and fats adopted in the embodiment of the application, especially saturated oils and fats, have higher closed moisturizing effect compared with omega-3, omega-6 and omega-9 unsaturated fatty acids due to higher molecular weight; the skin softening and moisturizing effects of the anti-inflammatory acne-removing skin care composition can be further enhanced.
In some embodiments, the pH of the aqueous phase is 3.5-5.5, and salicylic acid and fruit acid can exert better anti-inflammatory and anti-acne effects in the acidic environment.
In some embodiments, the fruit acids include: at least one of glycolic acid, lactic acid, malic acid, citric acid and tartaric acid, and the fruit acids can accelerate the peeling of skin cutin, play a role in chemical peeling, and can enhance the acne removing effect of salicylic acid.
In some embodiments, the skin conditioning agent comprises: heat insensitive skin conditioners and heat sensitive skin conditioners. In some embodiments, the heat-insensitive skin conditioning agent comprises: at least one of polyols, gums and polysaccharides. In other embodiments, the heat-sensitive skin conditioning agent comprises: at least one of alcohols, vitamin C and its derivatives, plant extracts, amino acids, and oligopeptides. The conditioner can improve the skin feeling of the anti-inflammatory acne-removing skin care composition, and can enhance the effects of resisting wrinkles, whitening and the like of the anti-inflammatory acne-removing skin care composition.
In some embodiments, the preservative comprises: at least one of methylparaben, phenoxyethanol, ethylhexyl glycerin, sorbic acid, benzoic acid, potassium sorbate, sodium benzoate, chlorphenesin, p-hydroxyacetophenone, disodium EDTA, caprylyl glycol, citric acid, sodium citrate and sodium phytate, and the preservative can effectively prevent microbial contamination in the production of the formula and prevent microbial contamination of the formula in the use process of consumers and in the storage environment. The service cycle and the stability of the anti-inflammatory acne-removing skin care composition are improved.
The anti-inflammatory and anti-acne skin care composition disclosed by the embodiment of the application can be prepared by the following method.
In a second aspect, the embodiment of the application provides a preparation method of an anti-inflammatory acne-removing skin care composition, which comprises the following steps:
s10, mixing a heat-insensitive skin conditioner with water, adding salicylic acid under a temperature-rising condition, and dissolving and mixing to obtain a first mixed solution;
s20, cooling the first mixed solution, adding a heat-sensitive skin conditioner and tartaric acid, mixing and dissolving, and adding a preservative to obtain a water phase;
s30, obtaining omega-3 unsaturated fatty acid, omega-6 unsaturated fatty acid and omega-9 unsaturated fatty acid, and mixing with other grease to obtain an oil phase;
s40, mixing the oil phase and the water phase to obtain the anti-inflammatory acne-removing skin care composition.
According to the preparation method of the anti-inflammatory acne-removing skin care composition provided by the second aspect of the application, after the raw material components are obtained according to the formula amount, firstly, a heat-insensitive skin conditioner is mixed with water, and then the mixture is heated and added with salicylic acid for dissolving; and then, cooling the first mixed solution, adding a heat-sensitive skin conditioner and fruit acid, mixing and dissolving, and finally adding a preservative for dissolving to obtain a water phase. In addition, omega-3 polyunsaturated fatty acid, omega-6 polyunsaturated fatty acid, omega-9 unsaturated fatty acid and other oil are mixed to obtain oil phase. And mixing the water phase and the oil phase to obtain the anti-inflammatory acne-removing skin care composition. The preparation method of the anti-inflammatory acne-removing skin care composition provided by the embodiment of the application is simple in process, easy to operate, low in preparation cost and convenient for industrial large-scale production and application.
Specifically, in step S10, salicylic acid is water-soluble, but the solubility in water is not high, and if the water phase is added in combination with the skin conditioner with better water solubility in step S10, the skin conditioner may salt out salicylic acid, reduce the solubility of salicylic acid, slow down the dissolution rate of salicylic acid, and is not suitable for large-scale industrial production. Therefore, in step S10, the heat-insensitive skin conditioner is fully dissolved in water, and then heated to 50-60 ℃, and salicylic acid is added under the heating condition for dissolution, so as to increase the solubility of salicylic acid, increase the dissolution rate of salicylic acid, and eliminate the risk of salting out salicylic acid by other water-soluble substances.
In some embodiments, the heat-insensitive skin conditioning agent comprises: at least one of polyols, gums and polysaccharides. In some embodiments, heat insensitive skin conditioning agents include, but are not limited to, polyols such as propylene glycol, glycerin, butylene glycol; polysaccharides such as hyaluronic acid; and gums such as xanthan gum.
Specifically, in step S20, the first mixed solution is cooled to 45 ℃ or below, and then a heat-sensitive skin conditioner and fruit acid are added, mixed and dissolved, and then a preservative is added to obtain a water phase. Since the preservative has hydrophilic and hydrophobic groups in its chemical structure, if added and dissolved together with skin conditioners, fruit acids, etc., preservative molecules may form complexes with molecules of the raw material components, reducing the preservative efficacy of the preservative. Therefore, in step S20, the heat-sensitive skin conditioner and the fruit acid are dissolved first, and then the preservative is added for dissolution, so as to avoid the influence of the simultaneous mixing and dissolution of the preservative, the conditioner and the fruit acid on the preservative efficacy of the preservative.
In some embodiments, the heat-sensitive skin conditioning agent comprises: at least one of alcohols, vitamin C and its derivatives, plant extracts, amino acids (such as arginine), and oligopeptides (such as acetyl hexapeptide-8).
Specifically, in step S30, the step of obtaining an ω -3 polyunsaturated fatty acid, an ω -6 polyunsaturated fatty acid, and an ω -9 unsaturated fatty acid includes: omega-3 polyunsaturated fatty acids, omega-6 polyunsaturated fatty acids and omega-9 unsaturated fatty acids are obtained from cranberry seed oil and/or macadamia nut oil. Omega-3, omega-6 and omega-9 unsaturated fatty acids in the anti-inflammatory acne skin care composition can be extracted from natural oil such as cranberry seed oil and/or macadamia nut oil.
In some embodiments, omega-3 unsaturated fatty acids, omega-6 unsaturated fatty acids, and omega-9 unsaturated fatty acids are mixed with other oils at a temperature of 20-37 ℃ to provide better stability of the oil components.
Specifically, in step S40, the anti-inflammatory and anti-acne skin care composition is obtained by mixing the oil phase and the water phase. The anti-inflammatory acne-removing skin care composition prepared in the embodiment of the application can be layered in a standing state, and is applied to the surface of skin after being fully shaken up in practical use.
In a third aspect of the embodiments of the application, a method for using the anti-inflammatory acne-removing skin care composition is provided, wherein after the anti-inflammatory acne-removing skin care composition is obtained, the anti-inflammatory acne-removing skin care composition is shaken until the anti-inflammatory acne-removing skin care composition is in an emulsion state and then used.
According to the application method of the anti-inflammatory acne-removing skin care composition provided by the third aspect of the application, after the anti-inflammatory acne-removing skin care composition is obtained, the oil phase component and the water phase component of the composition can be separated in a standing state, so that the anti-inflammatory acne-removing skin care composition needs to be shaken before being used until the anti-inflammatory acne-removing skin care composition is in an oil-in-water emulsion state and then is applied to the surface of skin.
In order to make the details and operations of the above-mentioned embodiments of the present application clearly understood by those skilled in the art, and to make the progress of the anti-inflammatory and anti-acne skin care composition and the preparation method thereof remarkably apparent, the above-mentioned technical solutions are illustrated by the following examples.
Example 1
An anti-inflammatory acne-removing skin care composition comprises the following raw material components in the following table 1:
TABLE 1
Note that: as the polyunsaturated fatty acid is directly obtained from the natural oil by extraction and other modes, the natural oil often contains several polyunsaturated fatty acids at the same time, and the addition percentage content is difficult to be accurate to a point value and is expressed in a preferred interval. (same theory of the subsequent embodiment)
After the raw material components in the table 1 are obtained, the preparation of the anti-inflammatory acne-removing skin care composition comprises the following steps:
mixing a heat-insensitive skin conditioner with water, and adding salicylic acid for dissolving and mixing at 60 ℃ to obtain a first mixed solution;
cooling the first mixed solution to 40 ℃, adding a heat-sensitive skin conditioner and tartaric acid, mixing and dissolving, and adding a preservative to obtain a water phase;
obtaining omega-3 polyunsaturated fatty acid, omega-6 polyunsaturated fatty acid and omega-9 unsaturated fatty acid, and mixing with other oil to obtain oil phase;
and fourthly, mixing the oil phase and the water phase to obtain the anti-inflammatory acne-removing skin care composition.
Example 2
An anti-inflammatory acne-removing skin care composition is prepared by the same steps as example 1, and comprises the following raw material components in table 2:
TABLE 2
Example 3
An anti-inflammatory acne-removing skin care composition is prepared by the same steps as example 1, and comprises the following raw material components in table 3:
TABLE 3
Comparative example 1
An anti-inflammatory acne-removing skin care composition comprises the following raw material components in the following table 4:
TABLE 4
Comparative example 2
An anti-inflammatory acne-removing skin care composition comprises the following raw material components in the following table 5:
TABLE 5
Comparative example 3
An anti-inflammatory acne-removing skin care composition comprises the following raw material components in the following table 6:
TABLE 6
Further, in order to verify the advancement of the anti-inflammatory acne-removing skin care composition in the embodiment of the application, the anti-inflammatory acne-removing skin care compositions in the embodiments 1 to 3 and the comparative examples 1 to 3 are subjected to an effect experience test, and 4 experience degrees of the irritation in use, the comfort of the skin after use, the humidity retention of the skin after use and the acne-removing effect of each product are scored (1-5 points, the weakest 1 point and the strongest 5 points). The total number of the test results was 6 groups of 10 volunteers, 60 volunteers were recruited for testing and scoring, the volunteers were used continuously for 1 week, 2 times a day, and the score was counted and the average value was calculated after one week. The volunteers are 20-40 years old, the facial skin has no special sensitive constitution or damage, and the male and female are half ginseng, and the test results are shown in the following table 7:
TABLE 7
According to the user test results, compared with comparative examples 1-3, the anti-inflammatory acne-removing skin care composition in the embodiment 1-3 greatly improves the use comfort, humidity preservation and acne-removing effects of users, and obviously reduces the use irritation. The anti-inflammatory acne-removing skin care composition is characterized in that the oil and fat can form a hydrophobic film on the surface of the skin, inhibit the loss of moisture, prevent the skin from chapping, and have the effects of moistening, moisturizing, smoothing and the like, and the irritation of salicylic acid can be relieved. Meanwhile, omega-3, omega-6 and omega-9 unsaturated fatty acids obtained from natural vegetable oil and fat are not only antioxidants, but also can inhibit sebum oxidation of the acne muscle, and can resist inflammatory reaction of acne together with salicylic acid.
The above description is only exemplary of the present application and should not be taken as limiting the present application, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present application should be included in the protection scope of the present application.
Claims (14)
1. An anti-inflammatory acne-removing skin care composition is characterized by comprising the following components in percentage by mass based on 100% of the total mass of the anti-inflammatory acne-removing skin care composition: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; wherein the content of the first and second substances,
in the anti-inflammatory acne-removing skin care composition, the aqueous phase comprises: 0.1-2% of salicylic acid, 0-6% of fruit acid, 0-10% of a skin conditioner, 0.1-1% of a preservative and the balance of water;
in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 0.1-10% of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0-2.9% of other grease.
2. The anti-inflammatory acne-removing skin care composition according to claim 1, comprising, based on 100% of the total mass of the anti-inflammatory acne-removing skin care composition: 3 to 10 percent of oil phase and 90 to 97 percent of water phase; wherein the content of the first and second substances,
in the anti-inflammatory acne-removing skin care composition, the aqueous phase comprises: 0.1-2% of salicylic acid, 1-6% of fruit acid, 1-10% of a skin conditioner, 0.1-1% of a preservative and the balance of water;
in the anti-inflammatory acne-removing skin care composition, the oil phase comprises: 1 to 9.5 percent of omega-3, omega-6 and omega-9 unsaturated fatty acid and 0.5 to 2 percent of other grease.
3. The anti-inflammatory acne skin care composition of claim 1 or 2 comprising, based on 100% total of the omega-3, omega-6, and omega-9 unsaturated fatty acids:
27 to 36 percent of omega-3 unsaturated fatty acid,
34 to 45 percent of omega-6 unsaturated fatty acid,
19-32% of omega-9 unsaturated fatty acid.
4. The anti-inflammatory acne skin care composition of claim 3, wherein the omega-3 unsaturated fatty acids comprise: at least one of alpha-linolenic acid, eicosapentaenoic acid and docosahexaenoic acid;
and/or, the omega-6 unsaturated fatty acids comprise: at least one of linoleic acid, gamma-linoleic acid, conjugated linoleic acid, and arachidonic acid;
and/or, the omega-9 unsaturated fatty acids comprise: at least one of oleic acid, erucic acid and nervonic acid.
5. The anti-inflammatory acne-removing skin care composition according to claim 1, 2 or 4 wherein the pH of the aqueous phase is from 3.5 to 5.5;
and/or the water is deionized water.
6. The anti-inflammatory acne skin care composition of claim 1, wherein the additional oils comprise: at least one of isopropyl myristate, isopropyl palmitate, isononyl isononanoate, squalane, ethylhexyl isopalmitate, ethylhexyl palmitate, caprylic/capric triglyceride, hydrogenated polyisobutene, and hydrogenated polydecene.
7. The anti-inflammatory acne skin care composition of claim 5, wherein the fruit acid comprises: at least one of glycolic acid, lactic acid, malic acid, citric acid, tartaric acid;
and/or, the skin conditioning agent comprises: heat insensitive skin conditioners and heat sensitive skin conditioners.
8. The anti-inflammatory acne skin care composition of claim 7, wherein the heat-insensitive skin conditioning agent comprises: at least one of polyols, gums and polysaccharides;
and/or, the heat-sensitive skin conditioning agent comprises: at least one of alcohols, vitamin C and its derivatives, plant extracts, amino acids, and oligopeptides.
9. The anti-inflammatory and anti-acne skin care composition of any of claims 1, 6-8, wherein the preservative comprises: at least one of methylparaben, phenoxyethanol, ethylhexyl glycerin, sorbic acid, benzoic acid, potassium sorbate, sodium benzoate, chlorphenesin, p-hydroxyacetophenone, disodium EDTA, caprylyl glycol, citric acid, sodium citrate and sodium phytate.
10. A method of preparing an anti-inflammatory and anti-acne skin care composition as claimed in any one of claims 1 to 9, comprising:
mixing a heat-insensitive skin conditioner with water, and adding salicylic acid for dissolving and mixing under the condition of temperature rise to obtain a first mixed solution;
cooling the first mixed solution, adding a heat-sensitive skin conditioner and tartaric acid, mixing and dissolving, and adding a preservative to obtain a water phase;
after omega-3 unsaturated fatty acid, omega-6 unsaturated fatty acid and omega-9 unsaturated fatty acid are obtained, mixing the obtained product with other grease to obtain an oil phase;
and mixing the oil phase and the water phase to obtain the anti-inflammatory acne-removing skin care composition.
11. The method of preparing an anti-inflammatory and anti-acne skin care composition of claim 10, wherein the at elevated temperature conditions comprise: under the condition of 50-60 deg.C;
and/or, the cooling of the first mixed solution comprises: and cooling the first mixed solution to 45 ℃ or below.
12. The method of preparing an anti-inflammatory acne skin care composition according to claim 10 or 11 wherein the step of obtaining omega-3 polyunsaturated fatty acids, omega-6 polyunsaturated fatty acids and omega-9 unsaturated fatty acids comprises: obtaining the omega-3 polyunsaturated fatty acids, the omega-6 polyunsaturated fatty acids, and the omega-9 unsaturated fatty acids from cranberry seed oil and/or macadamia nut oil;
and/or mixing omega-3 unsaturated fatty acid, omega-6 unsaturated fatty acid and omega-9 unsaturated fatty acid with other oil at the temperature of 20-37 ℃ to obtain the oil phase.
13. The method of preparing an anti-inflammatory acne-removing skin care composition according to claim 10, wherein said heat-insensitive skin conditioning agent comprises: at least one of polyols, gums and polysaccharides;
and/or, the heat-sensitive skin conditioning agent comprises: at least one of alcohols, vitamin C and its derivatives, plant extracts, amino acids, and oligopeptides.
14. The use method of the anti-inflammatory acne-removing skin care composition is characterized in that the anti-inflammatory acne-removing skin care composition according to any one of claims 1 to 9 or the anti-inflammatory acne-removing skin care composition prepared by the method according to any one of claims 10 to 13 is obtained and then is shaken until the anti-inflammatory acne-removing skin care composition is in an emulsion state for use.
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