CN113632888A - Functional additive for reducing weaning stress of piglets and preparation method and application thereof - Google Patents
Functional additive for reducing weaning stress of piglets and preparation method and application thereof Download PDFInfo
- Publication number
- CN113632888A CN113632888A CN202110912026.3A CN202110912026A CN113632888A CN 113632888 A CN113632888 A CN 113632888A CN 202110912026 A CN202110912026 A CN 202110912026A CN 113632888 A CN113632888 A CN 113632888A
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- piglets
- parts
- functional additive
- monoglyceride
- weaning
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- 239000013538 functional additive Substances 0.000 title claims abstract description 104
- 238000002360 preparation method Methods 0.000 title abstract description 64
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims abstract description 93
- 238000000034 method Methods 0.000 claims abstract description 42
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims abstract description 24
- 235000021466 carotenoid Nutrition 0.000 claims abstract description 19
- 150000001747 carotenoids Chemical class 0.000 claims abstract description 19
- 150000002711 medium chain fatty acid esters Chemical class 0.000 claims abstract description 17
- 150000003365 short chain fatty acid esters Chemical class 0.000 claims abstract description 17
- 230000002265 prevention Effects 0.000 claims abstract description 14
- 239000002253 acid Substances 0.000 claims abstract description 8
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 8
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 8
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims abstract description 5
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims abstract description 3
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims description 24
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims description 24
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 11
- FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 claims description 10
- GHBFNMLVSPCDGN-UHFFFAOYSA-N caprylic acid monoglyceride Natural products CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 claims description 10
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 9
- 230000009467 reduction Effects 0.000 claims description 9
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims description 8
- 230000037406 food intake Effects 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims description 7
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims description 7
- 239000005018 casein Substances 0.000 claims description 7
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 7
- 235000021240 caseins Nutrition 0.000 claims description 7
- 230000035622 drinking Effects 0.000 claims description 7
- 239000006188 syrup Substances 0.000 claims description 7
- 235000020357 syrup Nutrition 0.000 claims description 7
- 239000004250 tert-Butylhydroquinone Substances 0.000 claims description 7
- 235000019281 tert-butylhydroquinone Nutrition 0.000 claims description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- 239000005639 Lauric acid Substances 0.000 claims description 5
- ARIWANIATODDMH-UHFFFAOYSA-N Lauric acid monoglyceride Natural products CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 claims description 5
- 235000012631 food intake Nutrition 0.000 claims description 5
- 229960002446 octanoic acid Drugs 0.000 claims description 5
- 241001122767 Theaceae Species 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 claims description 4
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 4
- 235000013824 polyphenols Nutrition 0.000 claims description 4
- 238000006467 substitution reaction Methods 0.000 claims description 4
- GYSCBCSGKXNZRH-UHFFFAOYSA-N 1-benzothiophene-2-carboxamide Chemical compound C1=CC=C2SC(C(=O)N)=CC2=C1 GYSCBCSGKXNZRH-UHFFFAOYSA-N 0.000 claims description 3
- 239000000654 additive Substances 0.000 claims description 3
- 230000000996 additive effect Effects 0.000 claims description 3
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 claims description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 3
- 235000010384 tocopherol Nutrition 0.000 claims description 3
- 229960001295 tocopherol Drugs 0.000 claims description 3
- 229930003799 tocopherol Natural products 0.000 claims description 3
- 239000011732 tocopherol Substances 0.000 claims description 3
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 3
- ARIWANIATODDMH-AWEZNQCLSA-N 1-lauroyl-sn-glycerol Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)CO ARIWANIATODDMH-AWEZNQCLSA-N 0.000 claims description 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims description 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims description 2
- ODCCQUXDUXHSBP-UHFFFAOYSA-N decanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCC(O)=O ODCCQUXDUXHSBP-UHFFFAOYSA-N 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
- FUZZWVXGSFPDMH-UHFFFAOYSA-M hexanoate Chemical compound CCCCCC([O-])=O FUZZWVXGSFPDMH-UHFFFAOYSA-M 0.000 claims description 2
- 238000000265 homogenisation Methods 0.000 claims description 2
- RIEABXYBQSLTFR-UHFFFAOYSA-N monobutyrin Chemical compound CCCC(=O)OCC(O)CO RIEABXYBQSLTFR-UHFFFAOYSA-N 0.000 claims description 2
- 125000005457 triglyceride group Chemical group 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 abstract description 18
- 235000021050 feed intake Nutrition 0.000 abstract description 13
- 230000000052 comparative effect Effects 0.000 description 26
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 description 10
- 239000000463 material Substances 0.000 description 10
- 239000000203 mixture Substances 0.000 description 9
- POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- 229940070765 laurate Drugs 0.000 description 8
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 description 8
- 235000010388 propyl gallate Nutrition 0.000 description 5
- 239000000473 propyl gallate Substances 0.000 description 5
- 229940075579 propyl gallate Drugs 0.000 description 5
- 238000009395 breeding Methods 0.000 description 4
- 230000001276 controlling effect Effects 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 4
- LKUNXBRZDFMZOK-GFCCVEGCSA-N Capric acid monoglyceride Natural products CCCCCCCCCC(=O)OC[C@H](O)CO LKUNXBRZDFMZOK-GFCCVEGCSA-N 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 235000021051 daily weight gain Nutrition 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 208000019901 Anxiety disease Diseases 0.000 description 2
- 230000036506 anxiety Effects 0.000 description 2
- -1 butyl monoglyceride Chemical compound 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 235000011837 pasties Nutrition 0.000 description 2
- 230000003938 response to stress Effects 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 241001061264 Astragalus Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- GONOPSZTUGRENK-UHFFFAOYSA-N benzyl(trichloro)silane Chemical compound Cl[Si](Cl)(Cl)CC1=CC=CC=C1 GONOPSZTUGRENK-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000002515 guano Substances 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 210000004233 talus Anatomy 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/02—Breeding vertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Environmental Sciences (AREA)
- Birds (AREA)
- Animal Behavior & Ethology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Fodder In General (AREA)
Abstract
The invention provides a functional additive for reducing weaning stress of piglets, and a preparation method and application thereof, wherein the functional additive comprises the following components in parts by weight: 10-20 parts of short-chain fatty acid ester, 20-40 parts of medium-chain fatty acid ester, 15-55 parts of carrier, 1-5 parts of antioxidant and 1-5 parts of carotenoid; the short-chain fatty acid ester comprises butyl acid monoglyceride and/or hexyl acid monoglyceride; the medium chain fatty acid ester comprises any one of caprylic monoglyceride, capric monoglyceride or lauric monoglyceride or a combination of at least two of them. In addition, the invention also provides a prevention and control method for reducing the weaning stress of the piglets, and the prevention and control method adopts different feeding modes and feeding methods before, during and after the weaning of the piglets. The functional additive and the prevention and control method provided by the invention can effectively reduce the weaning stress of the piglets, improve the daily feed intake and daily gain of the piglets and reduce the diarrhea rate.
Description
Technical Field
The invention belongs to the technical field of breeding, particularly relates to a functional additive for reducing piglet weaning stress, a preparation method and an application thereof, and particularly relates to a functional additive for reducing piglet weaning stress, which can effectively reduce stress response and improve piglet growth performance, and a preparation method and an application thereof.
Background
With the continuous progress of modern breeding technology, the weaning days of piglets are gradually advanced, and the piglets face psychological, nutritional, environmental, immunological and other stresses after weaning. The survival rate of the weaned piglets is a key link of pig breeding. In order to improve and reduce the weaning stress of piglets, a mode of adding creep feed and improving the environment is often adopted.
CN104938419A discloses a suckling piglet creep and feeding training method for reducing weaning stress, which is characterized in that creep and feeding training are respectively carried out on piglets of 5-7 days old and piglets of 8-28 days old in a suckling period so as to improve the weaning weight of the piglets and the adaptability of the piglets to solid feed during weaning, thereby reducing the weaning stress of the piglets. This patent technique discloses a training method of suckling piglet religion groove and ingestion, but does not disclose the prescription of religion groove material, to teach groove material add water stirring for pasty artificial assistance suckling piglet ingestion, increase the cost of labor, be difficult to realize industrialization and use, artifical forced suckling piglet ingestion also causes very big stress to suckling piglet itself, influence the normal growth of piglet, because teach groove material nutrition is abundant, very easily oxidation rancidity, if not timely feeding after adding water stirring for pasty, easy deterioration leads to piglet diarrhea, and then influence the growth of piglet.
CN107114322A discloses a feeding method for improving weaning stress resistance of piglets, comprising: 1) feeding the piglets with feed water once within 10-12 hours after weaning, wherein the feed water is prepared by mixing and dissolving brown sugar, vitamins for the piglets, glucose, astragalus polysaccharide and cold boiled water according to the mass ratio of 1-3:0.05-0.1:1-2:0.01-0.05:20, grabbing the feed for the piglets after drinking the feed water, enabling the piglets to recognize the feed, and selecting to eat or not eat and not to forcibly feed; 2) repeating the step 1 once every 10-12 hours within 3-5 days until the piglets eat the feed twice continuously; 3) feeding drinking water for 2-4 days, and feeding the feed once every 2-3 hours; 4) after 7-8 days, reducing the feeding frequency per day, and increasing the daily feed dosage according to the growth condition of piglets, wherein the feed is piglet feed, and the daily feed dosage in the steps 1) -3) is not more than 150 g/pig. The patent technology discloses a feeding method of the weaned piglets, wherein the feed is added after the weaned piglets are weaned, the piglet feed is used, the absorption and utilization rate of the weaned piglets to the piglet feed is limited, the piglets are contacted with the piglet feed for the first time, the indigestion, the diarrhea and the like of the piglets are easily caused, and in addition, the stress of environmental factors to the weaned piglets is not considered.
Because the reduction of the weaning stress of the piglets plays an important role in improving the survival rate of the weaned piglets, the current breeding method has poor effect. Therefore, how to provide a method capable of effectively reducing the weaning stress of piglets becomes a problem to be solved urgently.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a functional additive for reducing piglet weaning stress, a preparation method and an application thereof, and particularly provides a functional additive for reducing piglet weaning stress, which can effectively reduce stress response and improve piglet growth performance, and a preparation method and an application thereof. The functional additive provided by the invention can effectively reduce the weaning stress of piglets, improve the daily feed intake and daily gain of piglets, and reduce the diarrhea rate.
In order to achieve the purpose, the invention adopts the following technical scheme:
in a first aspect, the invention provides a functional additive for reducing weaning stress of piglets, which comprises the following components in parts by weight: 10-20 parts of short-chain fatty acid ester, 20-40 parts of medium-chain fatty acid ester, 15-55 parts of carrier, 1-5 parts of antioxidant and 1-5 parts of carotenoid.
The short chain fatty acid ester comprises butyl acid monoglyceride and/or hexyl acid monoglyceride.
The medium-chain fatty acid ester includes any one or a combination of at least two of caprylic monoglyceride, capric monoglyceride, or lauric monoglyceride, for example, a combination of caprylic monoglyceride and capric monoglyceride, a combination of capric monoglyceride and lauric monoglyceride, or a combination of caprylic monoglyceride, capric monoglyceride, and lauric monoglyceride, but is not limited to the above-listed combinations, and other combinations not listed within the above-mentioned combination range are also applicable.
The short-chain fatty acid ester may be present in an amount of 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts or 20 parts, the medium-chain fatty acid ester may be present in an amount of 20 parts, 22 parts, 24 parts, 26 parts, 28 parts, 30 parts, 32 parts, 34 parts, 36 parts, 38 parts or 40 parts, the carrier may be present in an amount of 15 parts, 20 parts, 25 parts, 30 parts, 35 parts, 40 parts, 45 parts, 50 parts or 55 parts, the antioxidant may be present in an amount of 1 part, 2 parts, 3 parts, 4 parts or 5 parts, the carotenoid may be present in an amount of 1 part, 2 parts, 3 parts, 4 parts or 5 parts, but the present invention is not limited to the above-mentioned values or combinations, and other values not listed in the above-mentioned values or combinations are also applicable.
The functional additive with the specific components and the proportion is compounded by the short-chain fatty acid ester, the medium-chain fatty acid ester and the carotenoid, and the synergistic effect is realized, so that the effect of the functional additive on reducing the weaning stress of the piglets is improved, the daily feed intake and the daily weight gain of the piglets are improved, and the diarrhea rate is reduced.
Preferably, the short chain fatty acid esters are monoglycerides of butyric acid and monoglycerides of caproic acid.
Preferably, the medium chain fatty acid ester is a combination of caprylic monoglyceride, capric monoglyceride and lauric monoglyceride.
Preferably, the mass ratio of the butyl acetic acid monoglyceride to the hexyl acetic acid monoglyceride is (2-5) to (1-3).
Preferably, the mass ratio of the caprylic monoglyceride, the capric monoglyceride and the lauric monoglyceride is (1-3): (2-4): (2-5).
In the mass ratio of the butyric acid monoglyceride and the caproic acid monoglyceride, the number of butyric acid monoglyceride may be 2 parts, 3 parts, 4 parts, or 5 parts, the number of caproic acid monoglyceride may be 1 part, 1.5 parts, 2 parts, 2.5 parts, or 3 parts, the number of caprylic acid monoglyceride may be 1 part, 1.5 parts, 2 parts, 2.5 parts, or 3 parts, the number of capric acid monoglyceride may be 2 parts, 2.5 parts, 3 parts, 3.5 parts, or 4 parts, and the number of lauric acid monoglyceride may be 2 parts, 3 parts, 4 parts, or 5 parts.
Preferably, in the monoglyceride butyrate, monoglyceride hexanoate, monoglyceride octanoate, monoglyceride decanoate and monoglyceride laurate, the substitution site of butyric acid, hexanoic acid, octanoic acid, decanoic acid and lauric acid is independently the sn-2 position of triglyceride.
The specific components further improve the effect of the functional additive on reducing the weaning stress of the piglets.
Preferably, the carrier comprises 5-15 parts of casein and 10-40 parts of maltose syrup by weight.
The casein may be present in an amount of 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or 15 parts, the maltose syrup may be present in an amount of 10 parts, 15 parts, 20 parts, 25 parts, 30 parts, 35 parts or 40 parts, but the present invention is not limited to the above-mentioned values, and other values not listed in the above-mentioned numerical ranges are also applicable.
Preferably, the antioxidant comprises any one or a combination of at least two of TBHQ (tert-butylhydroquinone), tea polyphenol, tocopherol or PG (propyl gallate), such as a combination of TBHQ and tea polyphenol, a combination of tea polyphenol and PG, or a combination of PG and TBHQ, but is not limited to the above-listed combinations, and other combinations not listed within the above-mentioned combinations are also applicable.
In a second aspect, the present invention provides a method for preparing the functional additive as described above, comprising the steps of:
mixing short-chain fatty acid ester and medium-chain fatty acid ester, heating and stirring until the short-chain fatty acid ester and the medium-chain fatty acid ester are completely dissolved to obtain an oil phase;
mixing and heating the antioxidant, the carotenoid and water, then mixing and stirring with the carrier, then mixing and heating with the oil phase for homogenization, and then drying to obtain the functional additive.
In a third aspect, the present invention provides the use of a functional additive as described above for reducing weaning stress in piglets.
In a fourth aspect, the invention also provides a prevention and control method for reducing weaning stress of piglets, which comprises the following steps:
(1) after the piglets are born, the piglets start to teach the trough, and the trough is cleaned before feeding every time, so that the feed eaten by the piglets is fresh;
(2) feeding the functional additive to piglets 7 days before weaning;
(3) after the piglets are weaned, the sows and the piglets are separately arranged, piglet toys are arranged in piglet rooms for the piglets to bite and play, and a heater is arranged;
(4) the piglets are weaned on the 0 th to 3 th days by adopting a limited feeding mode;
(5) after 3 days of weaning, the piglets had free food intake.
According to the prevention and control method, the functional additive is adopted, and the creep feed and the functional additive, the quantitative limited feeding, the free feeding, the psychological factors, the environmental factors and the like are organically combined, so that the weaning stress of the piglets can be effectively reduced, the diarrhea of the weaned piglets is further reduced, the growth performance of the weaned piglets is improved, the daily feed intake and daily gain of the piglets are improved, and the diarrhea rate is reduced; the warm and comfortable environment can be provided by placing the piglet toy and the heater, the anxiety of the weaned piglets is effectively transferred, the psychological comfort is improved, and the weaning stress of the piglets is further relieved.
Preferably, the period of the creep of step (1) is at least 7 days from the birth of the piglet, such as 7 days, 8 days or 9 days, but not limited to the above-mentioned values, and other values not listed in the above-mentioned range are also applicable.
Preferably, the process of teaching the creep in the step (1) is specifically as follows:
the creep feed is added every 2.5-3.5 hours between 6:00 in the morning and 9:00 in the evening, and 5-10g of creep feed is added every time, wherein the interval time of adding creep feed can be 2.5h, 2.7h, 2.9h, 3.1h, 3.3h or 3.5h, etc., the mass of the creep feed added every time can be 5g, 6g, 7g, 8g, 9g or 10g, etc., but is not limited to the values listed above, and other values not listed in the above numerical range are also applicable.
The creep can be selected from conventional creep and is commercially available.
Preferably, the feeding mode of the functional additive in the step (2) is a drinking mode.
Preferably, the ratio of the functional additive to water is 1 (90-110) g/mL, such as 1:90g/mL, 1:92g/mL, 1:94g/mL, 1:96g/mL, 1:98g/mL, 1:100g/mL, 1:102g/mL, 1:104g/mL, 1:106g/mL, 1:108g/mL, or 1:110g/mL, but not limited to the above-listed values, and other values within the above-mentioned range of values are equally applicable.
Preferably, the specific process of feeding the functional additive according to claim 1 or 2 to the piglets in step (2) is as follows:
the additive amount of the functional additive is 5-10 g/head/day 7 days before the weaning of the piglets;
the adding amount of the functional additive is 10-30 g/head/day on the 0-3 days after the piglets are weaned;
4-7 days after weaning of piglets, the addition amount of the functional additive is 5-10 g/head/day.
Wherein, the adding amount of the functional additive can be 5 g/head/day, 6 g/head/day, 7 g/head/day, 8 g/head/day, 9 g/head/day or 10 g/head/day for 7 days before the piglets are weaned, the adding amount of the functional additive can be 10 g/head/day, 12 g/head/day, 14 g/head/day, 16 g/head/day, 18 g/head/day, 20 g/head/day, 22 g/head/day, 24 g/head/day, 26 g/head/day, 28 g/head/day or 30 g/head/day for 0-3 days after the piglets are weaned, the adding amount of the functional additive can be 5 g/head/day, 30 g/head/day and the like for 4-7 days after the piglets are weaned, the adding amount of the functional additive can be 5 g/head/day, 6 g/head/day, 7 g/head/day, 8 g/head/day, 9 g/head/day, or 10 g/head/day, etc., but not limited to the above-listed values, and other values not listed in the above-mentioned numerical range are also applicable.
The specific process regulates and controls the addition of the functional additive according to the growth process of the piglets, can effectively improve the daily feed intake and daily gain of the piglets, reduce the diarrhea rate and relieve the weaning stress of the piglets.
Preferably, the heater in step (3) has a temperature of 26-30 deg.C, such as 26 deg.C, 27 deg.C, 28 deg.C, 29 deg.C or 30 deg.C, but not limited to the above-listed values, and other values not listed in the above-mentioned range of values are also applicable.
Preferably, the specific process of the limited feeding mode in the step (4) is as follows:
feeding the creep feed every 2.5-3.5 hours between 6:00 in the morning and 9:00 in the evening, cleaning the trough before feeding each time, and ensuring that the feed eaten by the piglets is fresh, wherein the feeding amount of the creep feed is 150 g/head/day.
The interval time of the feeding of the milk replacer can be 2.5h, 2.7h, 2.9h, 3.1h, 3.3h or 3.5h, etc., the feeding amount of the milk replacer can be 100 g/head/day, 110 g/head/day, 120 g/head/day, 130 g/head/day, 140 g/head/day or 150 g/head/day, etc., but is not limited to the above-mentioned values, and other values in the above-mentioned value range are also applicable.
Compared with the prior art, the invention has the following beneficial effects:
(1) the invention provides a functional additive for reducing piglet weaning stress, which improves the effect of the functional additive on piglet weaning stress reduction by adopting the compounding of short-chain fatty acid ester, medium-chain fatty acid ester and carotenoid and the synergistic effect, improves the daily feed intake and daily weight gain of piglets, reduces the diarrhea rate, the daily feed intake reaches more than 310g, the daily weight gain reaches more than 290g, the feed ratio reaches less than 1.08, and the diarrhea rate is reduced to less than 10%;
(2) the invention also provides a prevention and control method for reducing the weaning stress of piglets, by adopting the functional additive, and organically combining the creep feed with the functional additive, quantitative limited feeding, free feeding, psychological factors, environmental factors and the like, the weaning stress of the piglets can be effectively reduced, the diarrhea of the weaned piglets is further reduced, the growth performance of the weaned piglets is improved, the daily feed intake and daily gain of the piglets are improved, and the diarrhea rate is reduced; the warm and comfortable environment can be provided by placing the piglet toy and the heater, the anxiety of the piglets after weaning is effectively transferred, the psychological comfort is improved, and the weaning stress of the piglets is further relieved; and by controlling a specific flow and regulating the addition amount of the functional additive according to the growth process of the piglets, the daily feed intake and daily gain of the piglets can be effectively improved, the diarrhea rate is reduced, and the weaning stress of the piglets is relieved.
Detailed Description
To further illustrate the technical means and effects of the present invention, the following further describes the technical solution of the present invention with reference to the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.
In the following examples, the creep feed was purchased from proud biotechnology limited, guano, guang, under the product name bei ru;
in the glycerol monobutyrate, the glycerol caproate, the glycerol caprylate, the glycerol capric acid and the glycerol monolaurate, the substitution site of the butyric acid, the acetic acid, the octanoic acid, the decanoic acid and the lauric acid is the sn-2 site of the triglyceride.
Preparation example 1
The preparation example provides a functional additive for reducing weaning stress of piglets, which comprises the following components in parts by weight:
10 parts of butyl acid monoglyceride, 5 parts of caproic acid monoglyceride, 7.5 parts of caprylic acid monoglyceride, 11.25 parts of capric acid monoglyceride, 11.25 parts of lauric acid monoglyceride, 10 parts of casein, 25 parts of maltose syrup, 3 parts of TBHQ and 3 parts of carotenoid.
The preparation method comprises the following steps:
mixing and heating the monoglyceride butyrate, the monoglyceride hexanoate, the monoglyceride octanoate, the monoglyceride decanoate and the monoglyceride laurate to 70 ℃, and stirring until the monoglyceride decanoate, the monoglyceride octanoate, the monoglyceride decanoate and the monoglyceride laurate are completely dissolved to obtain an oil phase;
putting softened water into a proportioning cylinder, heating to 70 ℃, adding TBHQ and carotenoid to fully dissolve the materials, then adding casein and maltose syrup, stirring and maintaining the temperature to 70 ℃, then adding an oil phase for mixing, continuously maintaining the temperature to 70 ℃, homogenizing for 10 minutes, and spray drying to obtain the functional additive.
Preparation example 2
The preparation example provides a functional additive for reducing weaning stress of piglets, which comprises the following components in parts by weight:
6.67 parts of butyl acid monoglyceride, 3.33 parts of caproic acid monoglyceride, 8 parts of caprylic acid monoglyceride, 16 parts of capric acid monoglyceride, 16 parts of lauric acid monoglyceride, 5 parts of casein, 40 parts of maltose syrup, 1 part of tocopherol and 5 parts of carotenoid.
The preparation method is referred to preparation example 1.
Preparation example 3
The preparation example provides a functional additive for reducing weaning stress of piglets, which comprises the following components in parts by weight:
12.5 parts of butyl monoglyceride, 7.5 parts of hexyl monoglyceride, 5 parts of caprylic monoglyceride, 6.7 parts of capric monoglyceride, 8.3 parts of lauric monoglyceride, 15 parts of casein, 10 parts of maltose syrup, 5 parts of PG and 1 part of carotenoid.
The preparation method is referred to preparation example 1.
Preparation example 4
The preparation example provides a functional additive for reducing weaning stress of piglets, and the composition of the functional additive is the same as that of the preparation example 1 except that the functional additive does not contain the monoglyceride butyrate and the reduced part is distributed to the monoglyceride hexanoate.
The preparation method is referred to preparation example 1.
Preparation example 5
The preparation example provides a functional additive for reducing weaning stress of piglets, and the composition of the functional additive is the same as that of the preparation example 1 except that the additive does not contain monoglyceride hexanoate and the reduced part is distributed to monoglyceride butyrate.
The preparation method is referred to preparation example 1.
Preparation example 6
The preparation example provides a functional additive for reducing weaning stress of piglets, and the composition is consistent with that of preparation example 1 except that 7.5 parts of caprylic monoglyceride, 11.25 parts of capric monoglyceride and 11.25 parts of lauric monoglyceride are replaced by 30 parts of caprylic monoglyceride.
The preparation process is referred to example 1.
Preparation example 7
The preparation example provides a functional additive for reducing weaning stress of piglets, and the composition is the same as that of preparation example 1 except that 7.5 parts of caprylic monoglyceride, 11.25 parts of capric monoglyceride and 11.25 parts of lauric monoglyceride are replaced by 12 parts of caprylic monoglyceride and 18 parts of capric monoglyceride.
The preparation method is referred to preparation example 1.
Comparative preparation example 1
This comparative preparation example provides a functional additive for reducing weaning stress of piglets, which is the same as in example 1 except that the composition does not contain monoglyceride butyrate, monoglyceride hexanoate, monoglyceride octanoate, monoglyceride decanoate and monoglyceride laurate, and a reduced portion is allocated to carotenoids.
The preparation process is referred to example 1.
Comparative preparation example 2
This comparative preparation provides a functional additive for reducing weaning stress in piglets, which is the same as in example 1 except that the composition does not contain carotenoids, monoglycerides of caprylic acid, monoglycerides of capric acid and monoglycerides of lauric acid, and the reduced fraction is proportionally distributed to monoglycerides of butyric acid and monoglycerides of caproic acid.
The preparation process is referred to example 1.
Comparative preparation example 3
This comparative preparation provides a functional additive for reducing weaning stress in piglets, which is the same as in example 1 except that the composition does not contain monoglyceride butyrate, monoglyceride hexanoate and carotenoid and the reduced portion is proportionally allocated to monoglyceride octanoate, monoglyceride decanoate and monoglyceride laurate.
The preparation process is referred to example 1.
Comparative preparation example 4
This comparative preparation provides a functional additive for reducing weaning stress in piglets, which is identical to example 1 except that the composition does not contain monoglyceride butyrate and monoglyceride hexanoate, and the reduced portion is proportionally allocated to monoglyceride octanoate, monoglyceride decanoate, monoglyceride laurate and carotenoid.
The preparation process is referred to example 1.
Comparative preparation example 5
This comparative preparation provides a functional additive for reducing weaning stress of piglets, which is the same as in example 1 except that the composition does not contain monoglyceride caprylate, monoglyceride caprate and monoglyceride laurate, and the reduced portion is proportionally allocated to monoglyceride butyrate, monoglyceride hexanoate and carotenoid.
The preparation process is referred to example 1.
Comparative preparation example 6
This comparative preparation provides a functional additive for reducing weaning stress in piglets, which is the same as in example 1 except that no carotenoid is contained, and a reduced portion is proportionally allocated to monoglyceride butyrate, monoglyceride hexanoate, monoglyceride octanoate, monoglyceride decanoate, and monoglyceride laurate.
The preparation process is referred to example 1.
Example 1
The embodiment provides a prevention and control method for reducing weaning stress of piglets, which comprises the following specific steps:
(1) feeding the creep feed every 3 hours from 6:00 in the morning to 9:00 in the evening when the piglets start to creep at the age of 7 days of birth, wherein 7g of the creep feed is fed every time, and the feed tank is cleaned before feeding every time to ensure that the feed taken by the piglets is fresh;
(2) the functional additive for reducing the weaning stress of the piglets provided by the preparation example 1 is added from 7 days before the weaning of the piglets, the addition amount of the functional additive is 7 g/head/day, the functional additive is added in three times in the morning, in the middle of the morning and in the evening, the functional additive is added in a drinking mode, and the ratio of water to the functional additive is 100:1 mL/g;
the adding amount of the functional additive is 20 g/head/day on the 0 th to 3 th days of the weaning of the piglets;
the adding amount of the functional additive is 7 g/head/day on the 4 th to 7 th days of the weaning of the piglets.
(3) After weaning, the piglets are kept in the delivery room, after the sows are driven out of the delivery room, piglet toys are placed in the delivery room for the piglets to bite and play, and a heater is placed at the temperature of 28 ℃;
(4) feeding the piglets in a limited feeding mode on the 0 th to 3 rd days of weaning, wherein the creep feed is added every 3 hours from 6:00 in the morning to 9:00 in the evening, the amount of the creep feed is 130 g/head/day, and the feed trough is cleaned before each feeding so as to ensure that the feed eaten by the piglets is fresh;
(5) after 3 days of weaning, the piglets had free food intake.
Example 2
The embodiment provides a prevention and control method for reducing weaning stress of piglets, which comprises the following specific steps:
(1) feeding the piglets to the creep trough at the beginning of 7 days of birth, adding the creep trough material every 2.5 hours from 6:00 in the morning to 9:00 in the evening, adding 5g of the creep trough material every time, and cleaning the creep trough before adding the creep trough material every time to ensure that the feed taken by the piglets is fresh;
(2) the functional additive for reducing the weaning stress of the piglets provided by the preparation example 2 is added from 7 days before the weaning of the piglets, the addition amount of the functional additive is 5 g/head/day, the functional additive is added in three times in the morning, in the middle of the morning and in the evening, the functional additive is added in a drinking mode, and the ratio of water to the functional additive is 100:1 mL/g;
the adding amount of the functional additive is 30 g/head/day on the 0 th to 3 th day of the weaning of the piglets;
the adding amount of the functional additive is 5 g/head/day on the 4 th to 7 th days of the weaning of the piglets.
(3) After weaning, the piglets are kept in the delivery room, after the sows are driven out of the delivery room, piglet toys are placed in the delivery room for the piglets to bite and play, and a heater is placed at the temperature of 26 ℃;
(4) feeding the piglets in a limited feeding mode on the 0 th to 3 rd days of weaning, wherein the creep feed is added every 3 hours from 6:00 in the morning to 9:00 in the evening, the amount of the creep feed is 100 g/head/day, and the feed trough is cleaned before each feeding, so that the feed fed to the piglets is fresh;
(5) after 3 days of weaning, the piglets had free food intake.
Example 3
The embodiment provides a prevention and control method for reducing weaning stress of piglets, which comprises the following specific steps:
(1) feeding the piglets to the creep trough at the beginning of 7 days of birth, adding the creep trough material every 3.5 hours from 6:00 in the morning to 9:00 in the evening, adding 10g of the creep trough material every time, and cleaning the creep trough before adding the creep trough material every time to ensure that the feed taken by the piglets is fresh;
(2) the functional additive for reducing the weaning stress of the piglets provided by the preparation example 3 is added from 7 days before the weaning of the piglets, the addition amount of the functional additive is 10 g/head/day, the functional additive is added in three times in the morning, in the middle of the morning and in the evening, the functional additive is added in a drinking mode, and the ratio of water to the functional additive is 100:1 mL/g;
the adding amount of the functional additive is 10 g/head/day on the 0 th to 3 th day of the weaning of the piglets;
the adding amount of the functional additive is 10 g/head/day on the 4 th to 7 th days of the weaning of the piglets.
(3) After weaning, the piglets are kept in the delivery room, after the sows are driven out of the delivery room, piglet toys are placed in the delivery room for the piglets to bite and play, and a heater is placed at the temperature of 30 ℃;
(4) feeding the piglets in a limited feeding mode on the 0 th to 3 rd days of weaning, wherein the creep feed is added every 3 hours from 6:00 in the morning to 9:00 in the evening, the amount of the creep feed is 150 g/head/day, and the feed trough is cleaned before each feeding, so that the feed fed to the piglets is fresh;
(5) after 3 days of weaning, the piglets had free food intake.
Examples 4 to 7
Examples 4 to 7 respectively provide a method for preventing and controlling piglet weaning stress reduction, which is the same as example 1 except that the functional additive for reducing piglet weaning stress provided by the preparation example 1 in the step (2) is respectively replaced by the same amount of the functional additive for reducing piglet weaning stress provided by the preparation examples 4 to 7.
Comparative examples 1 to 6
Comparative examples 1 to 6 respectively provide a method for preventing and controlling the reduction of the weaning stress of piglets, and the specific steps are the same as those of example 1 except that the functional additive for reducing the weaning stress of piglets provided in the preparation example 1 in the step (2) is replaced by the same amount of the functional additive for reducing the weaning stress of piglets provided in the comparative preparation examples 1 to 6.
Comparative example 7
The comparative example provides a prevention and control method for reducing weaning stress of piglets, which comprises the following specific steps:
(1) the piglets start to creep at the beginning of 7 days of birth and meet the requirement that the piglets have creep feed at any time period;
(2) the piglets are continuously left in the delivery room after weaning, and the sows are driven out of the delivery room;
(3) the piglets are fed independently after weaning.
Comparative example 8
The comparative example provides a prevention and control method for reducing weaning stress of piglets, which comprises the following specific steps:
(1) the piglets start to creep at the beginning of 7 days of birth and meet the requirement that the piglets have creep feed at any time period;
(2) the functional additive for reducing the weaning stress of the piglets provided by the preparation example 1 is added from 7 days before the weaning of the piglets, the addition amount of the functional additive is 7 g/head/day, the functional additive is added in three times in the morning, in the middle of the morning and in the evening, the functional additive is added in a drinking mode, and the ratio of water to the functional additive is 100:1 mL/g;
the adding amount of the functional additive is 20 g/head/day on the 0 th to 3 th days of the weaning of the piglets;
the adding amount of the functional additive is 7 g/head/day on the 4 th to 7 th days of the weaning of the piglets.
(3) After weaning, the piglets are kept in the delivery room, and the sows are driven out of the delivery room;
(4) the piglets are fed independently after weaning.
Comparative example 9
The comparative example provides a method for preventing and controlling piglet weaning stress, which is consistent with the example 1 except that the step (2) is not included in the specific steps.
Effect verification:
selecting 480 piglets, averagely dividing into 16 groups, feeding each group by the prevention and control method for reducing the weaning stress of the piglets provided by the examples 1-7 and the comparative examples 1-9 till the 14 th day of weaning of the piglets, disciplining and calculating the daily gain, daily feed intake, feed ratio and diarrhea rate of the weaned piglets, and calculating the average value, wherein the result is as follows:
the data show that the functional additive and the prevention and control method for reducing the weaning stress of the piglets can obviously reduce the weaning stress of the piglets, improve the daily feed intake and daily gain of the piglets and reduce the diarrhea rate and the feed ratio; compared with the comparative examples 1 and 1-6, the functional additive for reducing the piglet weaning stress improves the effect of the functional additive for reducing the piglet weaning stress, improves the daily gain, and reduces the diarrhea rate and the feed ratio by adopting the compounding of the short-chain fatty acid ester, the medium-chain fatty acid ester and the carotenoid and the synergistic action; compared with the examples 1 and 4-7, the invention can find that the functional additive for reducing the piglet weaning stress further improves the reduction effect of the functional additive for reducing the piglet weaning stress by optimizing the specific short-chain fatty acid ester and the medium-chain fatty acid ester, improves the daily feed intake and daily gain of the piglet, and reduces the diarrhea rate and the feed ratio; comparing example 1 with comparative example 7, it can be found that the weaning stress of piglets can be significantly reduced compared to the conventional feeding method; comparing example 1, comparative example 9 and comparative examples 7-8, it can be found that the weaning stress of piglets can be reduced, the daily feed intake and daily gain of piglets are improved, and the diarrhea rate and the feed ratio are reduced by adding the specific functional additive.
The applicant states that the functional additive for reducing piglet weaning stress and the preparation method and application thereof are illustrated by the above examples, but the invention is not limited by the above examples, i.e. the invention is not limited by the above examples. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.
The preferred embodiments of the present invention have been described in detail, however, the present invention is not limited to the specific details of the above embodiments, and various simple modifications may be made to the technical solution of the present invention within the technical idea of the present invention, and these simple modifications are within the protective scope of the present invention.
It should be noted that the various technical features described in the above embodiments can be combined in any suitable manner without contradiction, and the invention is not described in any way for the possible combinations in order to avoid unnecessary repetition.
Claims (10)
1. The functional additive for reducing the weaning stress of the piglets is characterized by comprising the following components in parts by weight: 10-20 parts of short-chain fatty acid ester, 20-40 parts of medium-chain fatty acid ester, 15-55 parts of carrier, 1-5 parts of antioxidant and 1-5 parts of carotenoid;
the short-chain fatty acid ester comprises butyl acid monoglyceride and/or hexyl acid monoglyceride;
the medium chain fatty acid ester comprises any one of caprylic monoglyceride, capric monoglyceride or lauric monoglyceride or a combination of at least two of them.
2. The functional additive according to claim 1, wherein the short-chain fatty acid ester is monoglyceride butyrate and monoglyceride hexanoate;
preferably, the medium-chain fatty acid ester is a combination of monoglycerides of caprylic acid, capric acid and lauric acid;
preferably, in the glycerol monobutyrate, the glycerol caproate, the glycerol caprylate, the glycerol capric acid and the glycerol monolaurate, the substitution site of the butyric acid, the acetic acid, the octanoic acid, the decanoic acid and the lauric acid is independently the sn-2 position of the triglyceride;
preferably, the carrier comprises 5-15 parts of casein and 10-40 parts of maltose syrup by weight;
preferably, the antioxidant comprises TBHQ, tea polyphenol, tocopherol or PG, either alone or in combination of at least two.
3. A method for preparing the functional additive according to claim 1 or 2, wherein the method comprises the steps of:
mixing short-chain fatty acid ester and medium-chain fatty acid ester, heating and stirring until the short-chain fatty acid ester and the medium-chain fatty acid ester are completely dissolved to obtain an oil phase;
mixing and heating the antioxidant, the carotenoid and water, then mixing and stirring with the carrier, then mixing and heating with the oil phase for homogenization, and then drying to obtain the functional additive.
4. Use of a functional additive according to claim 1 or 2 for reducing weaning stress in piglets.
5. A prevention and control method for reducing weaning stress of piglets is characterized by comprising the following steps:
(1) after the piglets are born, the piglets start to teach the trough, and the trough is cleaned before feeding every time, so that the feed eaten by the piglets is fresh;
(2) feeding the functional additive according to claim 1 or 2 to piglets 7 days before weaning;
(3) after the piglets are weaned, the sows and the piglets are separately arranged, piglet toys are arranged in piglet rooms for the piglets to bite and play, and a heater is arranged;
(4) the piglets are weaned on the 0 th to 3 th days by adopting a limited feeding mode;
(5) after 3 days of weaning, the piglets had free food intake.
6. The method for reducing weaning stress of piglets according to claim 5, wherein the time of the creep of step (1) is at least 7 days from the birth of the piglets;
preferably, the process of teaching the creep in the step (1) is specifically as follows:
adding 5-10g of creep feed every 2.5-3.5 hours between 6:00 in the morning and 9:00 in the evening.
7. The method for preventing and controlling piglet weaning stress reduction according to claim 5 or 6, wherein the feeding mode of the functional additive in the step (2) is drinking mode;
preferably, the feed-liquid ratio of the functional additive to the water is 1 (90-110) g/mL.
8. The method for preventing and controlling the reduction of weaning stress of piglets according to any of claims 5-7, wherein the specific process of feeding the functional additive of claim 1 or 2 to the piglets in step (2) is as follows:
the additive amount of the functional additive is 5-10 g/head/day 7 days before the weaning of the piglets;
the adding amount of the functional additive is 10-30 g/head/day on the 0-3 days after the piglets are weaned;
4-7 days after weaning of piglets, the addition amount of the functional additive is 5-10 g/head/day.
9. The method for preventing and controlling piglet weaning stress reduction according to any one of claims 5-8, wherein the temperature of the heater in step (3) is 26-30 ℃.
10. The method for preventing and controlling the reduction of weaning stress of piglets according to any one of claims 5-9, wherein the specific process of the limited feeding mode in step (4) is as follows:
feeding the creep feed every 2.5-3.5 hours between 6:00 in the morning and 9:00 in the evening, cleaning the trough before feeding each time, and ensuring that the feed eaten by the piglets is fresh, wherein the feeding amount of the creep feed is 150 g/head/day.
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| CN115005159A (en) * | 2022-06-14 | 2022-09-06 | 广州朴成生物科技有限公司 | Breeding method for maintaining intestinal health of piglets and application of breeding method |
| CN115024412A (en) * | 2022-06-14 | 2022-09-09 | 广州朴成农牧科技有限公司 | Functional compound for promoting growth of piglets and preparation method and application thereof |
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