CN113456534A - Oil-control acne-removing mixture with multiple skin-care effects and preparation method thereof - Google Patents
Oil-control acne-removing mixture with multiple skin-care effects and preparation method thereof Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
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Abstract
The invention relates to the technical field of acne-removing mixtures, and discloses an oil-controlling acne-removing mixture with multiple skin-care effects and a preparation method thereof. The oil-control acne-removing mixture with multiple skin-care effects promotes the bactericidal acne-removing agent to break through a skin cutin barrier through the bactericidal acne-removing agent and the composite penetration promoter, quickly prints acne, reduces excessive sebum secretion through conditioning sebum by the sebum conditioner, radically prevents the recurrence of acne, removes acne marks, lightens skin color and resists aging through nursing skin by the skin conditioner, and achieves multiple skin-care effects while having an acne-removing effect.
Description
Technical Field
The invention relates to the technical field of acne-removing mixtures, and particularly relates to an oil-controlling acne-removing mixture with multiple skin-care effects and a preparation method thereof.
Background
Acne-removing products are an important fine classification in cosmetics, and more than 80% of people in the age range of 12-45 years are affected by acne of different degrees. At present, acne-removing products mainly comprise two types, one type is a medical acne-removing product, most of the acne-removing products mainly comprise antibiotics and hormones, have quick response, but have great damage to skin, and are easy to relapse after being stopped; the other type is a cosmetic acne removing product, which takes salicylic acid, a bactericide, a traditional Chinese medicine extract and the like as effective components, and the components have high irritation to skin or slow effect, have single function and cannot meet the daily care of acne skin.
Thus, there is a need for an oil-controlling acne-removing mixture with multiple skin-care effects to solve the above-mentioned problem of single function of the conventional acne-removing product.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides the oil-controlling acne-removing mixture with multiple skin-care effects, has the advantages of multiple skin care and the like, and solves the problem of single skin-care effect in the background art.
(II) technical scheme
In order to achieve the purpose, the invention provides the following technical scheme: the oil-controlling and acne-removing mixture with multiple skin care effects comprises a solvent, a penetration enhancer, a pH regulator, a bactericidal acne-removing agent, a sebum conditioner, a skin conditioner and a thickening agent, wherein the penetration enhancer, the pH regulator, the bactericidal acne-removing agent, the sebum conditioner and the skin conditioner are fused through the solvent and the thickening agent.
Preferably, the solvent comprises 30-90 parts of deionized water and is used as a solvent for other components in the formula.
Preferably, the penetration enhancer comprises 0.5-20.00 parts of isoprene glycol, 0.5-10.00 parts of 1, 3-propylene glycol, 0.5-10.00 parts of 1, 2-pentanediol, 0.10-2.00 parts of 1, 2-hexanediol and 1.00-5.00 parts of polyethylene glycol/polypropylene glycol/polybutylene glycol-8/5/3 glycerol.
Preferably, the pH regulator comprises 0.00-0.60 parts of sodium hydroxide.
Preferably, the bactericidal acne-removing agent comprises-730.0001-0.10 parts of quaternary ammonium salt.
Preferably, the sebum conditioner comprises 0.10-5.00 parts of zinc gluconate, 0.01-0.50 part of nordihydroguaiaretic acid and 0.01-0.5 part of caryophyllin.
Preferably, the skin conditioning agent comprises 0.10-10.00 parts of nicotinamide, 0.10-10.00 parts of schizophyllan and 0.001-1.00 parts of peptide.
Preferably, the thickener comprises polyacrylate cross-linked polymer 60.1-3.00 parts.
A preparation method of an oil-controlling acne-removing mixture with multiple skin care effects comprises the following steps:
s1, mixing the components of the penetration enhancer, stirring and mixing at room temperature for 2 hours to ensure that the penetration enhancer is fully dissolved and uniformly dispersed;
s2, slowly adding the sterilizing and acne removing agent into the solution obtained in the step 1, stirring and dispersing uniformly at room temperature, and homogenizing for 10 minutes by using a homogenizer at the speed of 1200 RPM;
s3, stirring and mixing the solvent and the thickening agent at room temperature for 2 hours to ensure that the thickening agent is uniformly dispersed into a transparent viscous state; adding the components mixed in the step 2, adding a pH regulator, and uniformly stirring;
s4, adding a sebum conditioner after the steps S1-S3 are completed, and uniformly stirring;
s5, standing for 24 hours after all the steps are completed, and filtering by using a 200-mesh filter.
Compared with the prior art, the invention provides an oil-controlling acne-removing mixture with multiple skin care effects, which has the following beneficial effects:
the oil-control acne-removing mixture with multiple skin-care effects promotes the bactericidal acne-removing agent to break through a skin cutin barrier through the bactericidal acne-removing agent and the composite penetration promoter, quickly prints acne, reduces excessive sebum secretion through conditioning sebum by the sebum conditioner, radically prevents the recurrence of acne, removes acne marks, lightens skin color and resists aging through nursing skin by the skin conditioner, and achieves multiple skin-care effects while having an acne-removing effect.
Detailed Description
Technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Detailed description of the invention
The embodiment is an embodiment of the oil-controlling acne-removing mixture with multiple skin care effects.
The oil-controlling and acne-removing mixture with multiple skin care effects comprises a solvent, a penetration enhancer, a pH regulator, a bactericidal acne-removing agent, a sebum conditioner, a skin conditioner and a thickening agent, wherein the penetration enhancer, the pH regulator, the bactericidal acne-removing agent, the sebum conditioner and the skin conditioner are fused through the solvent and the thickening agent.
According to the technical scheme, the bactericidal acne removing agent and the composite penetration promoter promote the bactericidal acne removing agent to break through a skin cutin barrier and quickly print acne, excessive sebum secretion is reduced by conditioning sebum by the sebum conditioner, recurrence of acne is fundamentally prevented, acne marks are removed, complexion is lightened, aging is resisted by nursing skin by the skin conditioner, and the effects of removing acne and also having multiple skin care effects are achieved.
Specifically, the solvent comprises 30-90 parts of deionized water and is used as a solvent for other components in the formula.
Through the technical scheme, the deionized water in the solvent is used as the solvent of other components in the formula, so that the other components in the formula can be fused.
Specifically, the penetration enhancer comprises 0.5-20.00 parts of isoprene glycol, 0.5-10.00 parts of 1, 3-propylene glycol, 0.5-10.00 parts of 1, 2-pentanediol, 0.10-2.00 parts of 1, 2-hexanediol and 1.00-5.00 parts of polyethylene glycol/polypropylene glycol/polybutylene glycol-8/5/3 glycerol.
Through the technical scheme, the penetration enhancer is used for promoting the penetration of the functional components and providing skin foundation moisturizing.
Specifically, the pH regulator comprises 0.00-0.60 parts of sodium hydroxide.
Through the technical scheme, the sodium hydroxide has the sterilization effect and is mainly used for adjusting the pH value of a human body.
Specifically, the bactericidal acne-removing agent comprises-730.0001-0.10 parts of quaternary ammonium salt.
Through the technical scheme, a small amount of quaternary ammonium salt-73 with a bactericidal effect can inhibit the activity of the propionibacterium acnes and reduce the number of the propionibacterium acnes on the skin.
Specifically, the sebum conditioner comprises 0.10-5.00 parts of zinc gluconate, 0.01-0.50 part of nordihydroguaiaretic acid and 0.01-0.5 part of caryophyllin.
By adopting the technical scheme, the zinc gluconate is used for zinc deficiency diseases such as various skin acnes, recurrent aphthous ulcers and the like; nordihydroguaiaretic acid has antioxidant effect; the dianthus caryophyllus extract has certain surface activity, helps to stabilize emulsion, has antibacterial property, and can be used for preventing and treating acne by inhibiting 5 alpha-reductase activity, promoting hair growth and reducing gray hair, promoting collagen production, reducing elastin decomposition, and resisting aging and wrinkle, and can be used as humectant and external slimming agent for regulating sebum.
Specifically, the skin conditioner comprises 0.10-10.00 parts of nicotinamide, 0.10-10.00 parts of schizophyllan and 0.001-1.00 parts of peptide.
Through the technical scheme, the skin conditioner has the functions of removing acne marks, lightening skin color, repairing and resisting aging, wherein amide is a component of coenzyme I and coenzyme II and becomes the coenzyme of a plurality of dehydrogenases, the skin conditioner can influence normal respiration and metabolism of cells to cause pellagra when lacking, schizophyllin is an ideal component for cosmetics, has the effects of resisting inflammation and enhancing immunity, can effectively repair sunburnt skin, has the effects of moisturizing and resisting wrinkles on the skin and enables the skin to be tender and plump.
Specifically, the thickening agent comprises 60.1-3.00 parts of polyacrylate cross-linked polymer.
Through the technical scheme, the thickening agent is used for thickening and fusing the components into emulsion.
Detailed description of the invention
The embodiment is an embodiment of a preparation method of an oil-controlling and acne-removing mixture with multiple skin care effects.
A preparation method of an oil-controlling acne-removing mixture with multiple skin care effects comprises the following steps:
s1, mixing the components of the penetration enhancer, stirring and mixing at room temperature for 2 hours to ensure that the penetration enhancer is fully dissolved and uniformly dispersed;
s2, slowly adding the sterilizing and acne removing agent into the solution obtained in the step 1, stirring and dispersing uniformly at room temperature, and homogenizing for 10 minutes by using a homogenizer at the speed of 1200 RPM;
s3, stirring and mixing the solvent and the thickening agent at room temperature for 2 hours to ensure that the thickening agent is uniformly dispersed into a transparent viscous state; adding the components mixed in the step 2, adding a pH regulator, and uniformly stirring;
s4, adding a sebum conditioner after the steps S1-S3 are completed, and uniformly stirring;
s5, standing for 24 hours after all the steps are completed, and filtering by using a 200-mesh filter.
Detailed description of the invention
This example is the effect data of different proportions and temperatures in an oil-controlling and acne-removing composition with multiple skin care effects.
Proportioning experimental data:
note: the functional additive can be added with corresponding functional components according to the functional requirements required by the actual formula, and the functional additive in the embodiment is oligopeptide-1, so that the effects of brightening the skin color, promoting the skin to be refreshed and delaying the aging can be achieved.
Experimental data at ambient temperature:
although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. The oil-controlling and acne-removing mixture with multiple skin care effects comprises a solvent, a penetration enhancer, a pH regulator, a sterilizing and acne-removing agent, a sebum conditioner, a skin conditioner and a thickening agent, and is characterized in that: the penetration enhancer, the PH regulator, the bactericidal acne remover, the sebum conditioner and the skin conditioner are fused by a solvent and a thickening agent.
2. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the solvent comprises 30-90 parts of deionized water and is used as a solvent for other components in the formula.
3. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the penetration enhancer comprises 0.5-20.00 parts of isoprene glycol, 0.5-10.00 parts of 1, 3-propylene glycol, 0.5-10.00 parts of 1, 2-pentanediol, 0.10-2.00 parts of 1, 2-hexanediol and 1.00-5.00 parts of polyethylene glycol/polypropylene glycol/polybutylene glycol-8/5/3 glycerol.
4. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the pH regulator comprises 0.00-0.60 parts of sodium hydroxide.
5. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the sterilizing acne-removing agent comprises-730.0001-0.10 parts of quaternary ammonium salt.
6. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the sebum regulator includes zinc gluconate 0.10-5.00 weight portions, nordihydroguaiaretic acid 0.01-0.50 weight portions, and dianiline 0.01-0.5 weight portions.
7. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the skin conditioner comprises 0.10-10.00 parts of nicotinamide, 0.10-10.00 parts of schizophyllan and 0.001-1.00 parts of peptide.
8. The oil-controlling and acne-removing mixture with multiple skin care effects according to claim 1, characterized in that: the thickener comprises polyacrylate crosslinked polymer 60.1-3.00 parts.
9. A preparation method of an oil-controlling acne-removing mixture with multiple skin care effects is characterized by comprising the following steps: the method comprises the following steps:
s1, mixing the components of the penetration enhancer, stirring and mixing at room temperature for 2 hours to ensure that the penetration enhancer is fully dissolved and uniformly dispersed;
s2, slowly adding the sterilizing and acne removing agent into the solution obtained in the step 1, stirring and dispersing uniformly at room temperature, and homogenizing for 10 minutes by using a homogenizer at the speed of 1200 RPM;
s3, stirring and mixing the solvent and the thickening agent at room temperature for 2 hours to ensure that the thickening agent is uniformly dispersed into a transparent viscous state; adding the components mixed in the step 2, adding a pH regulator, and uniformly stirring;
s4, adding a sebum conditioner after the steps S1-S3 are completed, and uniformly stirring;
s5, standing for 24 hours after all the steps are completed, and filtering by using a 200-mesh filter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110865688.XA CN113456534A (en) | 2021-07-29 | 2021-07-29 | Oil-control acne-removing mixture with multiple skin-care effects and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110865688.XA CN113456534A (en) | 2021-07-29 | 2021-07-29 | Oil-control acne-removing mixture with multiple skin-care effects and preparation method thereof |
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| CN113456534A true CN113456534A (en) | 2021-10-01 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108338947A (en) * | 2018-03-13 | 2018-07-31 | 江苏德和生物科技有限公司 | A kind of skin care compositions with acne-removing, skin care formulation and preparation method thereof |
| CN110151585A (en) * | 2019-07-04 | 2019-08-23 | 广东天源生物科技有限公司 | One kind having whitening desalination acne print performance oligopeptides stoste and preparation method thereof |
| CN111588815A (en) * | 2020-05-29 | 2020-08-28 | 溯源生命科技股份有限公司 | Acne-removing traditional Chinese medicine composition, application thereof and acne-removing balancing essence containing composition |
-
2021
- 2021-07-29 CN CN202110865688.XA patent/CN113456534A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108338947A (en) * | 2018-03-13 | 2018-07-31 | 江苏德和生物科技有限公司 | A kind of skin care compositions with acne-removing, skin care formulation and preparation method thereof |
| CN110151585A (en) * | 2019-07-04 | 2019-08-23 | 广东天源生物科技有限公司 | One kind having whitening desalination acne print performance oligopeptides stoste and preparation method thereof |
| CN111588815A (en) * | 2020-05-29 | 2020-08-28 | 溯源生命科技股份有限公司 | Acne-removing traditional Chinese medicine composition, application thereof and acne-removing balancing essence containing composition |
Non-Patent Citations (2)
| Title |
|---|
| （美）库宁: "《皮肤保养手册》", 31 July 2009, 吉林出版集团有限责任公司 * |
| 杨彤: "《美容药物学》", 30 April 2007, 中国医药科技出版社 * |
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