CN102793635A - Spot-diminishing whitening cream and preparation method thereof - Google Patents
Spot-diminishing whitening cream and preparation method thereof Download PDFInfo
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- CN102793635A CN102793635A CN2012102834174A CN201210283417A CN102793635A CN 102793635 A CN102793635 A CN 102793635A CN 2012102834174 A CN2012102834174 A CN 2012102834174A CN 201210283417 A CN201210283417 A CN 201210283417A CN 102793635 A CN102793635 A CN 102793635A
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Abstract
The invention discloses a spot-diminishing whitening cream and a preparation method thereof. The cream comprises the following ingredients: A, a spot-diminishing whitening ingredient as a main body; B, a spot-diminishing whitening ingredient as an auxiliary ingredient; C, an oil phase ingredient; D, a water phase ingredient; E, a thickening stabilizing ingredient; and F, an auxiliary agent. The preparation method comprises the following steps: heating up the ingredient C to 70-90 DEG C, preserving the heat at 70-80 DEG C, adding the ingredient A and the ingredient B and uniformly stirring, heating up the ingredient D to 70-90 DEG C, preserving the heat at 70-80 DEG C, adding the ingredient E and uniformly stirring, pumping the ingredient C into a vacuum emulsification pot, then slowly pumping the ingredient D into to mix, homogenizing for 5-10 min, preserving the heat for 5-15 min with stirring, cooling by vacuum pumping, homogenizing for 2-3 min at 55-65 DEG C, continuing to cooling by vacuum pumping, uniformly stirring, adding the ingredient F at 35-45 DEG C, and uniformly stirring. The cream is safe and effective, has good whitening effect, and can prevent color spots, accelerate the metabolism and discharge of melanin, and enduringly diminish spots and whiten.
Description
[technical field]
The present invention relates to a kind of light speckles, beautification and white cream cosmetic and preparation method thereof, belong to the cosmetics technical field.
[background technology]
People like skin pigment to be evenly distributed, and sensation is clean beautiful, but with advancing age, Effect of Environmental, pigmentation can take place and form mottle in skin, influences specious.People have studied a lot of methods in order to desalinate the mottle skin whitening, hide the physiology that early stage chemistry whitens till now by primary physics and whiten, and people are changed into and improved light speckles, beautification and white effect under the prerequisite that guarantees high security from pursue whitening effect singlely.
The cosmetics of light speckles, beautification and white in the market, the whitening effect that has is good to have spalling effect to skin, injury skin, easily repeatedly, and the natural and safe that has but whitening effect is poor, all not fully up to expectations.
[summary of the invention]
The objective of the invention is to overcome the deficiency of prior art, provide a kind of safe, effective and stable, can quicken the light speckles, beautification and white cream cosmetic that the melanin metabolism is discharged.
Another object of the present invention is for a kind of method for preparing of this light speckles, beautification and white cream cosmetic is provided.
The present invention adopts following technical scheme to achieve these goals:
A kind of light speckles, beautification and white cream cosmetic is characterized in that percentage composition comprises following component by weight:
A, the light speckles, beautification and white component 0.2～6.0% of main body
B, auxiliary light speckles, beautification and white component 0.91～6.15%
C, oil phase components 12.0～35.0%
D, water component 51.35～86.69%
E, thickening stabilization component 0.1～0.5%
F, auxiliary agent component 0.1～1.0%.
Aforesaid a kind of light speckles, beautification and white cream cosmetic is characterized in that the light speckles, beautification and white component of described main body comprises following weight percentage component:
4-methoxyl group salicylic acid potassium salt 0.1～3.0%
Tranamic acid 0.1～3.0%.
Among the present invention, 4-methoxyl group salicylic acid potassium salt, promptly 4MSK (4-Methoxy Salicylic Acid KCI) is the medicinal whitening composition of just succeeding in developing after the very long research.The main effect of 4MSK is to let and receives ultraviolet radiation, causes horny layer disorderly, overlapping, produces chronic dyskeratosis and the black speck, the freckle skin that cause; One has the effect of improving dyskeratosis, can also block really from the source that Mai Laning melanin generates, and suppresses Mai Laning and generates; The generation of prevention black speck, freckle; Have and suppress melanic generation, prevent the mottle that generates because of Exposure to Sunlight, the effect of freckle.4MSK not only has the effect that suppresses the melanin generation, more can adjust the situation that the keratinization process has some setbacks.4MSK can make the factor amount of damaged part recover, and lets the factor of each aspect can both play a role in the melanin discharge process, lights the guide lamp that melanin is discharged, and lets melanin no longer lose the direction of leaving.
Pass bright acid among the present invention and have another name called tranexamic acid, tranamic acid, English Cyklokapron (Transamin by name; Transansamin, Tranexamic Acid, trans-4-aminomethyl cyclohexanecarboxylic acid); Passing bright acid is white crystalline powder, odorless, mildly bitter flavor; Be prone to dissolving in the water, almost insoluble in ethanol, acetone, chloroform or ether.
Pass its molecular formula of bright acid: C8H15NO2 molecular weight: 157.2.
Passing bright acid is a kind of protease inhibitor; Ability CKIs enzyme is to the catalytic action of peptide bond hydrolysis; Thereby stoped activity like enzymes such as inflammatory protease; And then suppressed the confusion of the epidermis cell function at black speck position, and suppress melanin enhancer crowd, the approach of the melanin generation of thoroughly breaking off again forming because of ultraviolet radiation.Promptly let black speck no longer thicken, enlarge and increase, thereby can prevent and improve the pigmentation of skin effectively.
Medically be applied to the diagnosis and treatment of aneurysm Aranea nethike embrane bleed bottom, educational circles is referred to as disconnected blood inflammation as the coagulant purposes, and unexpected discovery of diagnosis and treatment process has the side effect that skin is bleached, and signs so be utilized in the medicinal prescription of chloasma hepaticum treatment and melanin Shen Dian.Tranexamic acid whitening mechanism simultaneously and rapidly Tyrosinase inhibitory activity of enzymes and melanoma cells, and prevent melanin accumulation case, as can block ultraviolet radiation to eliminate the formation of melanin degradation path of travel.In the course of treatment of whitening fast, serve as main collocation vitamin C phosphoric acid fat magnesium salt APMg to pass bright sour composition.
In recent years, pass the whitening composition that bright acid is a kind of power of on skin care products, having patented.Clinical research has for many years confirmed to pass bright acid and can whiten and spot fading quick-actingly, makes skin present the perfect skin matter that pale soft and moist, bright crystalline substance passes through.
Pass bright acid and traditional whitening composition comparison can give expression to effect stability, limited by the high temperature production environment, do not need the protection transmission effect of all kinds of carriers, still can reach whitening effect, and the nonirritant effect.Bulletin consumption maximum concentration is 3%, and it is about 0.5% that cosmetics are made consumption.
If what pass that bright acid focuses on is effect, the demand of 4MSK promotes vis medicatrix naturae exactly so.Because when the skin metabolism process has some setbacks, the old useless cutin of epidermis can't all come off, and not only lets colour of skin deepening heavy, also lets melanin continue to be accumulated in the skin simultaneously, when skin shines ultraviolet once again, and also can the activation melanocyte.And added the article of whitening of 4MSK, and can let the outermost cutin of skin healthy, let melanin discharge smoothly, with uses of arranging in pairs or groups each other of all types of whitening products, just can improve the whitening effect of original commodity of whitening.More than 50 times of penetrating agent or transdermal agent show bright development prospect.
Aforesaid a kind of light speckles, beautification and white cream cosmetic is characterized in that described auxiliary light speckles, beautification and white component comprises following weight percentage component:
Aforesaid a kind of light speckles, beautification and white cream cosmetic is characterized in that described oil phase components comprises following weight percentage component:
Aforesaid a kind of light speckles, beautification and white cream cosmetic is characterized in that described water component comprises following weight percentage component:
Aforesaid a kind of light speckles, beautification and white cream cosmetic is characterized in that described thickening stabilization component is a carbomer.
Aforesaid a kind of light speckles, beautification and white cream cosmetic is characterized in that described auxiliary agent component is one or both mixture in essence, the antiseptic.
A kind of method for preparing above-mentioned light speckles, beautification and white cream cosmetic is characterized in that may further comprise the steps:
(1) C is warmed up to 70～90 ℃ mutually, is incubated 70～80 ℃, add again A mutually with B mutually, stir;
(2) D is warmed up to 70～90 ℃ mutually, is incubated 70～80 ℃, add the E phase again, stir;
(3) earlier with C phase suction vacuum emulsification pot, slowly suction D mixes mutually again, homogenizing 5～10min, the cooling of insulated and stirred 5～15min. evacuation;
In the time of (4) 55～65 ℃, homogenizing 2-3min continues the evacuation cooling, stirs;
Add the F phase in the time of (5) 35～45 ℃, stir, physical and chemical index gets final product after the assay was approved.
The present invention has following advantage with respect to prior art:
1, product safety is effective, and the composition of not violating a ban adds, and can see in a week has obvious light speckle effect in whitening effect, two weeks, and connecting continues can play the effect of consolidating Whitening, spot with two months.
2, have the melanic generation of inhibition, and prevent the melanin gathering; Prevent the mottle that generates because of Exposure to Sunlight, the effect of freckle.
The present invention with 4MSK with pass collaborative composite in addition other the auxiliary whitening compositions of bright acid, quicken the melanin metabolism to discharge, can lasting light speckles, beautification and white, realized that people are high to light speckles, beautification and white cosmetics safety property, effective and stable requirement.
[specific embodiment]
Below in conjunction with specific embodiment the present invention is further described:
Embodiment 1:
The light speckles, beautification and white cream cosmetic of the present invention, its by weight percentage composition comprise following component:
A, the light speckles, beautification and white component 0.2% of main body
B, auxiliary light speckles, beautification and white component 0.91%
C, oil phase components 12.0%
D, water component 86.69%
E, thickening stabilization component 0.1%
F, auxiliary agent component 0.1%;
The light speckles, beautification and white component of wherein said main body is made up of following weight percentage component:
4-methoxyl group salicylic acid potassium salt 0.1%
Pass bright sour 0.1%;
Wherein said auxiliary light speckles, beautification and white component is made up of following weight percentage component:
Wherein said oil phase components is made up of following weight percentage component:
Wherein said water component is made up of following weight percentage component:
Wherein said thick stabilization component is the carbomer of 0.1% weight percentage;
Wherein said adjuvant component is the essence of 0.1% weight percentage.
The preparation of present embodiment realizes through following steps:
(1) C is warmed up to 70 ℃ mutually, is incubated 70 ℃, add again A mutually with B mutually, stir;
(2) D is warmed up to 70 ℃ mutually, is incubated 70 ℃, add the E phase again, stir;
(3) earlier with C phase suction vacuum emulsification pot, slowly suction D mixes mutually again, homogenizing 5min, insulated and stirred 5min, evacuation cooling;
In the time of (4) 55 ℃, homogenizing 2min continues the evacuation cooling, stirs;
Add the F phase in the time of (5) 35 ℃, stir, physical and chemical index promptly obtains the present embodiment product after the assay was approved.
Embodiment 2:
The light speckles, beautification and white cream cosmetic of the present invention, its by weight percentage composition comprise following component:
A, main body Whitening, spot component 4.0%
B, auxiliary Whitening, spot component 3.58%
C, oil phase components 24.0%
D, water component 67.62%
E, thickening stabilization component 0.3%
F, auxiliary agent component 0.5%;
The light speckles, beautification and white component of wherein said main body is made up of following weight percentage component:
4-methoxyl group salicylic acid potassium salt 2.0%
Pass bright sour 2.0%;
Wherein said auxiliary light speckles, beautification and white component is made up of following weight percentage component:
Wherein said oil phase components is made up of following weight percentage component:
Wherein said water component is made up of following weight percentage component:
Wherein said thickening stabilization component is the carbomer of 0.3% weight percentage;
Wherein said auxiliary agent component is the essence of 0.5% weight percentage.
The preparation of present embodiment realizes through following steps:
(1) C is warmed up to 80 ℃ mutually, is incubated 75 ℃, add again A mutually with B mutually, stir;
(2) D is warmed up to 80 ℃ mutually, is incubated 75 ℃, add the E phase again, stir;
(3) earlier with C phase suction vacuum emulsification pot, slowly suction D mixes mutually again, homogenizing 8min, the cooling of insulated and stirred 10min. evacuation;
In the time of (4) 60 ℃, homogenizing 2.5min continues the evacuation cooling, stirs;
Add the F phase in the time of (5) 40 ℃, stir, physical and chemical index promptly obtains the present embodiment product after the assay was approved.
Embodiment 3:
The light speckles, beautification and white cream cosmetic of the present invention, its by weight percentage composition comprise following component:
A, main body Whitening, spot component 6.0%
B, auxiliary Whitening, spot component 6.15%
C, oil phase components 35.0%
D, water component 51.35%
E, thickening stabilization component 0.5%
F, auxiliary agent component 1.0%;
The light speckles, beautification and white component of wherein said main body is made up of following weight percentage component:
4-methoxyl group salicylic acid potassium salt 3.0%
Pass bright sour 3.0%;
Wherein said auxiliary light speckles, beautification and white component is made up of following weight percentage component:
Wherein said oil phase components is made up of following weight percentage component:
Wherein said water component is made up of following weight percentage component:
Wherein said thickening stabilization component is the carbomer of 0.5% weight percentage.
Wherein said auxiliary agent component is made up of following components in weight percentage content:
Essence 0.6%
Antiseptic 0.4%.
The preparation of present embodiment realizes through following steps:
(1) C is warmed up to 90 ℃ mutually, is incubated 80 ℃, add again A mutually with B mutually, stir;
(2) D is warmed up to 90 ℃ mutually, is incubated 80 ℃, add the E phase again, stir;
(3) earlier with C phase suction vacuum emulsification pot, slowly suction D mixes mutually again, homogenizing 10min, the cooling of insulated and stirred 15min. evacuation;
In the time of (4) 65 ℃, homogenizing 3min continues the evacuation cooling, stirs;
Add the F phase in the time of (5) 45 ℃, stir, physical and chemical index promptly obtains the present embodiment product after the assay was approved.
Light speckles, beautification and white cream cosmetic to embodiment 1 to embodiment 3 is done some testing performance indexes, and it is tested as follows
1. outward appearance: white is to faint yellow fine and smooth cream frost
2.pH value: 4.0-7.0
3. viscosity: 100000-150000mpa.s
4. heat-resistant stability investigation (48 ℃ * 24h): qualified
5. cold-resistant study on the stability (15 ℃ * 24h): qualified.
Method for using of the present invention is to use sooner or later, gets and smears face in right amount, or have speckle position emphasis to smear, and massage causes absorption gently.
The control experiment of light speckles, beautification and white cream cosmetic result of use of the present invention:
The beauty treatment circle generally is divided into seven types with skin: seven types of neutral skin (normal skin), oily skin, dry skin, sensitive skin, mixed skin, aging property skin, problem skins etc.Specifically:
1, oily skin: this type of skin complexion is dark, corse sweat pore, and sebum secretion is vigorous, and skin greasing is not easy to produce wrinkle, long easily acne, the seat skin ulcer, its pH value is between 5.6-6.6, and is defeated and dispersed immediately when foundation cream is relatively poor during cosmetic, sweats easily.
2, dry skin: the sebum secretion amount is few, does not have greasy feeling, and long easily tiny wrinkle stimulates relatively sensitivity to external world, and xerosis cutis is chapped easily, washes back skin with fancy soap and tingles, and can be divided into two kinds of hydropenia and oil starvations.The preceding kind is more common in more than 35 years old and the old people, and the back is planted and is more common in youngster, and its pH value is between 4.5-5;
3, neutral skin: be exactly normal skin, its pH value is between 5-5.6, and it is healthy desirable skin, and the moist high resilience of non-greasy loses pore, and is ruddy glossy, is not easy to wear out.
4, mixed skin: between dryness and oily skin, showing in the trigonum of having is greasy, and hole skin is thick then to show dry skin in eye and other place.Be more common in the 25-35 age in year;
5, allergic skin: skin stimulates responsive to external world, and allergic phenomenas such as skin is red, swollen, twinge, erythra just appear in (as: make apply some make up etc.) when receiving environmental stimuli.All medicines, pollen, cosmetics (like cosmetics such as lipstick, speckle dispelling class, fat-reducing class, hair dye, perfume), chemical substance (as painting etc.), animal skin, seafood (like Eriocheir sinensis etc.), plant (like Fructus Mangifera Indicae, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) etc.) are hot and cold, metal etc. all allergic phenomena can occur.
6, aging property skin: skin occurs lax, dry, matt, and sebum secretion is few, wrinkle often occurs.Be more common in middle-aged and elderly people and sentimental women.
7, problem skin: all Symptomatic skin that goes wrong all is referred to as problem skin with it.Problem skin mainly comprises mottle skin (chloasma, freckle, cyasma, butterfly spot, radiation spot etc.), acne, seat skin ulcer, speckle tinea, red blood streak, folliculitis, decortication, eczema, erythra, fester, various dermatitis, facial paralysed trace, nevus, carbuncle, cellulitis, treatment, skin ulcer or the like.
Object of study:
From the beauty treatment place, choose the trier who suffers from mottle of above-mentioned 7 types of skin attributes, especially face's actual state is relatively poor, as test crowd of the present invention.
Specifically be divided into 7 and organize greatly, be respectively:
(1) oiliness group; (2) dryness group; (3) neutral group; (4) Combination group; (5) anaphylaxis group; (6) aging property group; (7) problem group.
Every big group is divided into four groups again, and wherein group one is a matched group, and 100 examples are observed by every group.
Experimental technique:
Group's one usefulness is not added 4MSK and the blank comfort frost that passes bright acid, every day 2 times, uses continuously 1 month.
The light speckles, beautification and white cream cosmetic of group's dual-purpose embodiment of the invention 1, used 1 month continuously at every day 2 times.
The light speckles, beautification and white cream cosmetic of group's three usefulness embodiment of the invention 2, used 1 month continuously at every day 2 times.
The light speckles, beautification and white cream cosmetic of group's four-function embodiment of the invention 3, used 1 month continuously at every day 2 times.
Experimental result is seen table 1
Interpretation of result:
1, product of the present invention all has good Whitening, spot effect for the problem of various skin matter, compares the improvement that all has in various degree with the general cosmetics of blank frost.But the just onset of about two weeks, one month effect is fairly obvious.
2, product of the present invention has splendid desalination effect for symptoms such as freckle, the skin ulcer of fullying recover from an illness, acne, blackhead, chloasma, withered and yellow black face, chloasma, sun speckles, and whitening effect is preferably arranged.
Claims (8)
1. light speckles, beautification and white cream cosmetic is characterized in that percentage composition comprises following component by weight:
A, the light speckles, beautification and white component 0.2～6.0% of main body
B, auxiliary light speckles, beautification and white component 0.91～6.15%
C, oil phase components 12.0～35.0%
D, water component 51.35～86.69%
E, thickening stabilization component 0.1～0.5%
F, auxiliary agent component 0.1～1.0%.
2. a kind of light speckles, beautification and white cream cosmetic according to claim 1 is characterized in that the light speckles, beautification and white component of described main body comprises following weight percentage component:
4-methoxyl group salicylic acid potassium salt 0.1～3.0%
Pass bright sour 0.1～3.0%.
3. a kind of light speckles, beautification and white cream cosmetic according to claim 1 is characterized in that described auxiliary light speckles, beautification and white component comprises following weight percentage component:
4. a kind of light speckles, beautification and white cream cosmetic according to claim 1 is characterized in that described oil phase components comprises following weight percentage component:
5. a kind of light speckles, beautification and white cream cosmetic according to claim 1 is characterized in that described water component comprises following weight percentage component:
6. a kind of light speckles, beautification and white cream cosmetic according to claim 1 is characterized in that described thickening stabilization component is a carbomer.
7. according to each described a kind of light speckles, beautification and white cream cosmetic among the claim 1-6, it is characterized in that described auxiliary agent component is one or both mixture in essence, the antiseptic.
8. method for preparing the said light speckles, beautification and white cream cosmetic of claim 1 is characterized in that may further comprise the steps:
(1) C is warmed up to 70～90 ℃ mutually, is incubated 70～80 ℃, add again A mutually with B mutually, stir;
(2) D is warmed up to 70～90 ℃ mutually, is incubated 70～80 ℃, add the E phase again, stir;
(3) earlier with C phase suction vacuum emulsification pot, slowly suction D mixes mutually again, homogenizing 5～10min, the cooling of insulated and stirred 5～15min. evacuation;
In the time of (4) 55～65 ℃, homogenizing 2-3min continues the evacuation cooling, stirs;
Add the F phase in the time of (5) 35～45 ℃, stir, get final product.
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| CN2012102834174A CN102793635A (en) | 2012-08-10 | 2012-08-10 | Spot-diminishing whitening cream and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106309272A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Whitening cream and preparing method thereof |
| CN106377451A (en) * | 2016-08-30 | 2017-02-08 | 广州君恒生物科技有限公司 | Whitening cream |
| CN108743488A (en) * | 2018-08-21 | 2018-11-06 | 广州诺胜化妆品有限公司 | A kind of whitening lotion and preparation method thereof |
| CN109846741A (en) * | 2018-08-31 | 2019-06-07 | 上海珈凯生物科技有限公司 | A method of methoxysalicylic acid potassium, which is improved, with tranexamic acid compounds stability |
| CN112716828A (en) * | 2021-01-20 | 2021-04-30 | 广州易和生物科技有限公司 | Composition with skin whitening and spot lightening effects and skin care product thereof |
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| CN101507691A (en) * | 2008-02-13 | 2009-08-19 | 株式会社资生堂 | Oil-in-water emulsified milky skin cosmetic preparation |
| CN101590003A (en) * | 2009-06-23 | 2009-12-02 | 广州保税区雅兰国际化妆品有限公司 | A kind of whitening spot-relieving cream cosmetic and preparation method thereof |
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- 2012-08-10 CN CN2012102834174A patent/CN102793635A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101507691A (en) * | 2008-02-13 | 2009-08-19 | 株式会社资生堂 | Oil-in-water emulsified milky skin cosmetic preparation |
| CN101590003A (en) * | 2009-06-23 | 2009-12-02 | 广州保税区雅兰国际化妆品有限公司 | A kind of whitening spot-relieving cream cosmetic and preparation method thereof |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106309272A (en) * | 2016-08-24 | 2017-01-11 | 广东芭薇生物科技股份有限公司 | Whitening cream and preparing method thereof |
| CN106377451A (en) * | 2016-08-30 | 2017-02-08 | 广州君恒生物科技有限公司 | Whitening cream |
| CN108743488A (en) * | 2018-08-21 | 2018-11-06 | 广州诺胜化妆品有限公司 | A kind of whitening lotion and preparation method thereof |
| CN109846741A (en) * | 2018-08-31 | 2019-06-07 | 上海珈凯生物科技有限公司 | A method of methoxysalicylic acid potassium, which is improved, with tranexamic acid compounds stability |
| CN109846741B (en) * | 2018-08-31 | 2021-11-16 | 上海珈凯生物科技有限公司 | Method for improving compounding stability of potassium methoxysalicylate and tranexamic acid |
| CN112716828A (en) * | 2021-01-20 | 2021-04-30 | 广州易和生物科技有限公司 | Composition with skin whitening and spot lightening effects and skin care product thereof |
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Application publication date: 20121128 |