CN113520914A - Retinol sleeping mask and preparation method thereof - Google Patents

Retinol sleeping mask and preparation method thereof Download PDF

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Publication number
CN113520914A
CN113520914A CN202110891286.7A CN202110891286A CN113520914A CN 113520914 A CN113520914 A CN 113520914A CN 202110891286 A CN202110891286 A CN 202110891286A CN 113520914 A CN113520914 A CN 113520914A
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solution
mixing
retinol
stirring uniformly
stirring
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田贵丰
廖诗有
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Guangzhou Baoyan Biotech Co ltd
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Guangzhou Baoyan Biotech Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to a retinol sleeping mask which comprises the following components in percentage by weight: retinol palmitate, anti-wrinkle agent, wrapping agent, humectant, additive and water; the preparation method of the retinol mask comprises the following steps: mixing glycerol and the coating agent, and stirring; mixing retinol palmitate with anti-wrinkle agent, and stirring; adding water into the two mixed solutions after stirring uniformly, and stirring uniformly to obtain a solution A; mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, adding carbomer, stirring uniformly, adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium, cooling, adding p-hydroxyacetophenone and 1, 2-hexanediol, mixing and stirring uniformly to obtain solution B. And adding the solution A into the cooled solution B, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol sleeping mask. The retinol provided by the invention can effectively alleviate the stimulation to the skin, recover the elasticity of the skin and smooth fine wrinkles.

Description

Retinol sleeping mask and preparation method thereof
Technical Field
The invention relates to the field of cosmetics, and in particular relates to a retinol sleeping mask and a preparation method thereof.
Background
The retinol (vitamin A) and its derivatives can penetrate into skin, repair cells and restore skin elasticity, can reduce skin wrinkles, and has good anti-wrinkle effect. Thus, retinol and its derivatives play an important role in combating the aging process, and are important functional additives for many skin cream and anti-wrinkle products.
However, when retinol and its derivatives are used, many people have intolerance of their skin, which is manifested by extensive redness, stinging, dryness and peeling of the skin. And retinol and its derivatives are sensitive to light and heat and are not easily preserved under strong light and in hot environments.
Disclosure of Invention
In order to solve the problems that retinol and derivatives thereof cannot tolerate the skin and are sensitive to light and heat and not easy to store, the invention provides the retinol facial mask and the preparation method thereof, the retinol can effectively alleviate the stimulation of the retinol and the derivatives thereof to the skin, and enables the skin to recover elasticity, smooth fine wrinkles, resist oxidation and the like, so that the skin recovers a more yearly light healthy state; further enabling the product to be easily preserved.
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000011
Figure BDA0003196185710000021
further, the wrapping agent is one or two combinations of PPG-13-decyl tetradecyl alcohol polyether-24 and polyquaternium-61.
Further, the weight percentage of the PPG-13-decyl tetradecanol polyether-24 is 0.1-0.5%; the weight percentage of the polyquaternium-61 is 0.001-0.5%.
Further, the anti-wrinkle agent is one or two combinations of phytosterol/octyl dodecanol lauroyl glutamate and tocopherol.
Further, the humectant is one or a combination of more than two of sodium hyaluronate, methyl glucitol polyether-20 and glycosyl trehalose.
Further, the humectant may also include panthenol.
Further, the additive is one or the combination of more than two of xanthan gum, 1, 3-propylene glycol, carbomer, EDTA disodium, glycerol, p-hydroxyacetophenone and 1, 2-hexanediol.
The invention also provides a preparation method of the retinol sleeping mask, which comprises the following steps:
s1: mixing glycerol and the wrapping agent, and stirring to obtain solution A1;
mixing and stirring retinol palmitate with an anti-wrinkle agent to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 1-5% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at the temperature of 80-85 ℃, and preserving the temperature for 10-30min to obtain a solution B3;
s5: cooling the solution B3 to 65-70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 40-45 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol sleeping mask.
In summary, the present application has the following beneficial effects:
1. according to the invention, a nano-encapsulation technology is adopted, and the retinol palmitate in the retinol and the derivatives thereof is encapsulated through the properties of emulsification and oil-soluble active substances of PPG-13-decyltetradecanol polyether-24 and polyquaternium-61, so that the release of the retinol palmitate is effectively delayed, the stimulation to the skin is reduced, and the temperature-resistant and light-resistant sensitivity of the product is improved.
2. The retinol palmitate disclosed by the invention can accelerate skin metabolism, promote cell proliferation and simultaneously stimulate collagen generation;
the phytosterol/octyl dodecanol lauroyl glutamate can form a liquid crystal film, can cover the surface of the skin and has the function of softening and moistening the skin;
the tocopherol has antioxidant effect, and can promote wound healing, prevent inflammation and prevent skin roughness and chapping; also has effects of maintaining skin connective tissue, protecting skin from ultraviolet injury, etc., and can make skin feel soft and keep skin moisture;
in conclusion, the retinol palmitate, the phytosterol/octyldodecanol lauroyl glutamate and the tocopherol have the effects of moistening skin, resisting oxidation, diminishing inflammation and the like, and can smooth fine wrinkles of the skin, so that the skin recovers elasticity and keeps skin vitality.
Detailed Description
Example 1
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000031
Figure BDA0003196185710000041
the preparation method of the retinol sleeping mask comprises the following steps:
s1: mixing and stirring glycerol, PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 to obtain solution A1;
mixing retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate and tocopherol, and stirring to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding the water of 1, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at 80 ℃ and preserving the temperature for 10min to obtain a solution B3;
s5: cooling the solution B3 to 65 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 40 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol facial mask.
The mixing and stirring are carried out for 10min at the rotating speed of 1800 r/min.
Example 2
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000051
Figure BDA0003196185710000061
the preparation method of the retinol sleeping mask comprises the following steps:
s1: mixing and stirring glycerol, PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 to obtain solution A1;
mixing retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate and tocopherol, and stirring to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 5% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at 85 ℃ and preserving heat for 30min to obtain a solution B3;
s5: cooling the solution B3 to 70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 45 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol facial mask.
The mixing and homogenizing mean stirring for 15min at the rotating speed of 2200 r/min.
Example 3
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000071
the preparation method of the retinol sleeping mask comprises the following steps:
s1: mixing and stirring glycerol, PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 to obtain solution A1;
mixing retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate and tocopherol, and stirring to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 3% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at 83 ℃ and preserving heat for 20min to obtain a solution B3;
s5: cooling the solution B3 to 65-70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 43 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol facial mask.
The mixing and stirring are carried out for 13min at the rotating speed of 2000 r/min.
Example 4
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000081
Figure BDA0003196185710000091
the preparation method of the retinol sleeping mask comprises the following steps:
s1: mixing and stirring glycerol, PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 to obtain solution A1;
mixing retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate and tocopherol, and stirring to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 3% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at 83 ℃ and preserving heat for 20min to obtain a solution B3;
s5: cooling the solution B3 to 65-70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 43 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol facial mask.
The mixing and stirring are carried out for 13min at the rotating speed of 2000 r/min.
Example 5
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000101
the preparation method of the retinol sleeping mask comprises the following steps:
s1: mixing and stirring glycerol, PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 to obtain solution A1;
mixing retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate and tocopherol, and stirring to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 3% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at 83 ℃ and preserving heat for 20min to obtain a solution B3;
s5: cooling the solution B3 to 65-70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 43 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol facial mask.
The mixing and stirring are carried out for 13min at the rotating speed of 2000 r/min.
Example 6
A retinol sleeping mask comprises the following components in percentage by weight:
Figure BDA0003196185710000111
Figure BDA0003196185710000121
the preparation method of the retinol sleeping mask comprises the following steps:
s1: mixing and stirring glycerol, PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 to obtain solution A1;
mixing retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate and tocopherol, and stirring to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 3% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at 83 ℃ and preserving heat for 20min to obtain a solution B3;
s5: cooling the solution B3 to 65-70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 43 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol facial mask.
The mixing and stirring are carried out for 13min at the rotating speed of 2000 r/min.
Comparative example 1
The sleep mask comprises the following components in percentage by weight:
Figure BDA0003196185710000131
the method for preparing the sleep mask is different from that of the sleep mask in example 6 in that the retinol palmitate, the phytosterol/octyldodecanol lauroyl glutamate, the tocopherol, the PPG-13-decyltetradecanol polyether-24 and the polyquaternium-61 are not added, and the rest steps are the same.
Performance test
60 volunteers of 20-45 years old were recruited and all of them randomized into six groups of 10 persons each, the first group using an existing product, which is a commercially available retinol sleep mask. The second to sixth groups used the masks prepared in examples 3 to 6 and comparative example 1, respectively, 1 time per day for 28 consecutive days. The results of the measurements after 28 days are shown in table 1:
TABLE 1
Figure BDA0003196185710000141
As can be seen from table 1, the first group has a general skin improvement effect when compared with the second to fifth groups, which effectively shows that the product of the present invention has outstanding effects and advantages when compared with the existing products in the market.
The sixth group of products did not provide significant improvement in skin, and the sixth group did not include retinol palmitate, phytosterol/octyldodecanol lauroyl glutamate, tocopherol, PPG-13-decyltetradecanol polyether-24, polyquaternium-61, and the like. The second group to the fifth group have more remarkable effects, and the skin improvement effect is gradually increased, which effectively shows that the components have remarkable skin improvement effect. Further, the skin-improving effect of the present invention is more remarkable as the concentration of the above components is increased.
In conclusion, the invention adopts the nano-encapsulation technology, and the retinol palmitate in the retinol and the derivatives thereof is encapsulated through the emulsification of PPG-13-decyltetradecanol polyether-24 and polyquaternium-61 and the performance of oil-soluble active matters, so that the release of the retinol palmitate is effectively delayed, and the temperature resistance and light resistance sensitivity of the product are improved; reducing the irritation to the skin. The retinol palmitate disclosed by the invention can accelerate skin metabolism, promote cell proliferation and simultaneously stimulate collagen generation; the phytosterol/octyl dodecanol lauroyl glutamate can form a liquid crystal film, can cover the surface of the skin and has the function of softening and moistening the skin; the tocopherol has antioxidant effect, and can promote wound healing, prevent inflammation and prevent skin roughness and chapping; also has effects of maintaining skin connective tissue, protecting skin from ultraviolet injury, etc., and can make skin feel soft and keep skin moisture; in conclusion, the retinol palmitate, the phytosterol/octyldodecanol lauroyl glutamate and the tocopherol have the effects of moistening skin, resisting oxidation, diminishing inflammation and the like, and can smooth fine wrinkles of the skin, so that the skin recovers elasticity and keeps skin vitality.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.

Claims (8)

1. The retinol sleeping mask is characterized by comprising the following components in percentage by weight:
Figure FDA0003196185700000011
2. the retinol sleeping mask as claimed in claim 1, wherein:
the wrapping agent is one or two combinations of PPG-13-decyl tetradecyl alcohol polyether-24 and polyquaternium-61.
3. The retinol sleeping mask as claimed in claim 2, wherein:
the weight percentage of the PPG-13-decyl tetradecyl alcohol polyether-24 is 0.1-0.5%;
the weight percentage of the polyquaternium-61 is 0.001-0.5%.
4. The retinol sleeping mask as claimed in claim 1, wherein:
the anti-wrinkle agent is one or two of phytosterol/octyl dodecanol lauroyl glutamate and tocopherol.
5. The retinol sleeping mask as claimed in claim 1, wherein:
the humectant is one or a combination of more than two of sodium hyaluronate, methyl glucitol polyether-20 and glycosyl trehalose.
6. The retinol sleeping mask as claimed in claim 5, wherein:
the humectant further comprises panthenol.
7. A retinol sleeping mask as claimed in claim 3, wherein:
the additive is one or the combination of more than two of xanthan gum, 1, 3-propylene glycol, carbomer, EDTA disodium, glycerol, p-hydroxyacetophenone and 1, 2-hexanediol.
8. A method of preparing a retinol sleep mask as claimed in any of claims 1-7, which comprises the steps of:
s1: mixing glycerol and the wrapping agent, and stirring to obtain solution A1;
mixing and stirring retinol palmitate with an anti-wrinkle agent to obtain solution A2;
adding the solution A2 into the solution A1, mixing and stirring uniformly until the solution is transparent, adding 1-5% of water, mixing and stirring uniformly to obtain a solution A;
s2: mixing sodium hyaluronate, xanthan gum and 1, 3-propylene glycol, stirring uniformly, adding into water, and mixing and stirring uniformly to obtain solution B1;
s3: adding carbomer into solution B1, mixing and stirring to obtain solution B2;
s4: adding methyl glucitol polyether-20, glycosyl trehalose and EDTA disodium into a solution B2 at the temperature of 80-85 ℃, and preserving the temperature for 10-30min to obtain a solution B3;
s5: cooling the solution B3 to 65-70 ℃, adding p-hydroxyacetophenone and 1, 2-hexanediol, and mixing and stirring uniformly to obtain a solution B.
S6: adding the solution A into the solution B cooled to 40-45 ℃, mixing and stirring uniformly, adding panthenol, mixing and stirring uniformly to obtain the retinol sleeping mask.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113940897A (en) * 2021-12-03 2022-01-18 北京美丽臻颜化妆品有限公司 Preparation method of anti-aging composition, anti-aging composition and use method thereof

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