CN113424960A - Anti-fatigue traditional Chinese medicine health product and preparation method thereof - Google Patents
Anti-fatigue traditional Chinese medicine health product and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of health product preparation, and discloses an anti-fatigue traditional Chinese medicine health product and a preparation method thereof. The preparation method of the anti-fatigue traditional Chinese medicine health product comprises the following steps: weighing Changbai mountain black ant extract, cornu Cervi Pantotrichum powder, rhizoma Dioscoreae, radix astragali and Poria in proportion; extracting the weighed Changbai mountain black ant extract, Chinese yam, radix astragali and tuckahoe by a multifunctional extraction tank, and adding water for decocting for 3 times; filtering, mixing filtrates, concentrating, oven drying under reduced pressure, and pulverizing to obtain dry extract powder; mixing the obtained dry extract powder with the weighed antler powder to obtain mixed powder; granulating the mixed powder; sieving, drying to obtain dry granules, grading the prepared dry granules by using a 20-mesh sieve, uniformly mixing, and subpackaging to obtain the anti-fatigue health-care product. The health care product prepared by the invention can effectively resist fatigue and has high content of functional components.
Description
Technical Field
The invention belongs to the technical field of health product preparation, and particularly relates to an anti-fatigue traditional Chinese medicine health product and a preparation method thereof.
Background
At present: the fatigue in a broad sense includes physical fatigue, mental fatigue, psychological fatigue and mixed type fatigue. Traditional Chinese medicine has related records about fatigue in ancient books such as Huangdi's classic and plain questions, plain questions and pain-relieving treatises, and Jinkui jade function, the slightly edited and revised treatises, wherein fatigue is mainly attributed to liver function dominance and fatigue loss of primordial qi. The mechanism of fatigue generation is quite complex, and recent modern related researches suggest that the causes of fatigue are mainly attributed to the following three factors: 1. consumption of energy materials; 2. a large accumulation of metabolites; 3. changes in the environment in and out of the body, endocrine disorders, blood glucose lowering, ATP reduction, etc., which cause failure of the impulse of the central nervous system to generate or maintain the impulse to the muscles enough to meet the exercise needs, are the main causes of muscle fatigue during work.
The results of the World Health Organization (WHO) survey show that the global population is only 5% healthy, 20% sick, and 75% of the vast majority of the population is sub-healthy between healthy and sick. According to survey, the subhealth population in China accounts for about 60-70% of the total population. Through related researches, fatigue is one of the most common symptoms in sub-health, accounts for more than 40% of sub-health people, and is one of the causes most influencing the life quality of the sub-health people. According to the investigation of the world health organization, more than 35% of people worldwide are in fatigue state, especially 60% -75% of middle-aged male people in fatigue state. Along with social development, fatigue has become more and more non-negligible a problem commonly possessed by modern people, and related medical researches show that long-term fatigue can cause people to feel tired and contradictory to work and study, interpersonal relation disorder and symptoms accompanied by a plurality of systems simultaneously,
such as headache, dizziness, pharyngalgia, muscular and joint pain, anorexia, nausea, night sweat, etc., and often has the symptoms of difficulty in falling asleep, frequent arousal during sleep, daytime sleepiness, etc. Along with the concern of people on fatigue, huge anti-fatigue health care products are in need of oil.
The anti-fatigue health care products on the market at present are roughly divided into two types, wherein the two types are mainly the former two types. The first is a functional beverage; the second type of anti-fatigue health care product mainly comprises anti-fatigue plant active ingredients which are researched more in the prior art.
However, the two health products have limited fatigue relieving effect, and the products have low content of effective components and high preparation cost.
Through the above analysis, the problems and defects of the prior art are as follows: the existing anti-fatigue health care product has limited effect of relieving fatigue, low content of functional components and high preparation cost.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides an anti-fatigue traditional Chinese medicine health product. The invention is realized in such a way that the anti-fatigue traditional Chinese medicine health product is composed of Changbai mountain black ant extract, antler powder, Chinese yam, radix astragali and poria cocos according to the mass parts. Wherein, the feed comprises 10g of black ants, 6g of antler powder, 15g of Chinese yam, 10g of radix astragali and 10g of tuckahoe.
The invention also aims to provide a preparation method of the anti-fatigue traditional Chinese medicine health product, and the preparation method of the anti-fatigue traditional Chinese medicine health product comprises the following steps:
weighing Changbai mountain black ant extract, Chinese yam, radix astragali and tuckahoe in proportion, extracting, filtering, concentrating and crushing to prepare dry paste powder; mixing the prepared dry extract powder with cornu Cervi Pantotrichum powder, and granulating.
Further, the preparation method of the anti-fatigue traditional Chinese medicine health product comprises the following steps:
weighing Changbai mountain black ant extract, antler powder, Chinese yam, radix astragali and poria cocos according to a proportion;
step two, extracting the weighed Changbai mountain black ant extract, the yam, the radix astragali and the tuckahoe by a multifunctional extraction tank, and adding water for decocting for 3 times;
filtering, combining the filtrates, concentrating, drying under reduced pressure, and pulverizing to obtain dry extract powder;
step four, mixing the obtained dry paste powder with the weighed antler powder to obtain mixed powder; granulating the mixed powder;
and fifthly, sieving and drying to obtain dry granules, grading the prepared dry granules by using a 20-mesh sieve, uniformly mixing and subpackaging to obtain the anti-fatigue health-care product.
Further, in step two, the decocting comprises: adding 7 times of water for each decoction, and decocting for 1.5 hr each time.
Further, in step three, the concentrating comprises: concentrating the filtrate to obtain fluid extract of 1.25-1.28.
Further, in the third step, the drying under reduced pressure includes: and placing the obtained clear paste in a reduced pressure drying oven for reduced pressure drying.
Further, in step three, the pulverizing comprises: pulverizing the dried dry extract, and sieving with 80 mesh sieve.
Further, in step four, the granulating the mixed powder comprises: adding 90% ethanol into the total mixed powder to obtain uniform and appropriate soft material, and granulating.
Further, in step five, the screening comprises: sieving with 20 mesh sieve.
Further, in step five, the drying comprises: the drying temperature is 60-65 ℃.
By combining all the technical schemes, the invention has the advantages and positive effects that: the main raw materials of the invention are Changbai mountain black ant extract, antler powder, yam, radix astragali and tuckahoe. Changbai mountain black ant contains rich vitamins, micro element rope and essential amino acids, and has high medicinal value and health function, and higher nutritious element content than common ant or black ant; the astragalus root, the Chinese yam and the tuckahoe have obvious promotion effect on the antibody generating function of normal organisms. The existing research shows that the Changbai mountain black ants and the pilose antler both have the anti-fatigue function, and according to the theory of traditional Chinese medicine, the five medicines are applied in a matching way, and have the functions of reinforcing and reducing discharge, and reinforcing and attacking, and the formula is reasonable, scientific and effective.
The health product capsule prepared by the invention has bright and beautiful appearance, no improper bitter odor and convenient taking; the functional component index total protein content of the prepared health-care product is more than 20mg/100g, the functional component index astragaloside is more than 20mg/100g, and the microorganism index reaches the general standard of health-care (functional) food.
Drawings
Fig. 1 is a flow chart of a preparation method of the anti-fatigue traditional Chinese medicine health product provided by the embodiment of the invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Aiming at the problems in the prior art, the invention provides an anti-fatigue traditional Chinese medicine health product, which is described in detail below with reference to the accompanying drawings.
The anti-fatigue traditional Chinese medicine health product provided by the embodiment of the invention comprises Changbai mountain black ant extract, antler powder, Chinese yam, radix astragali and poria cocos in parts by mass.
As shown in fig. 1, the preparation method of the anti-fatigue traditional Chinese medicine health product provided by the embodiment of the invention comprises the following steps:
s101, weighing Changbai mountain black ant extract, antler powder, Chinese yam, radix astragali and poria cocos according to a proportion;
s102, extracting the weighed Changbai mountain black ant extract, Chinese yam, radix astragali and poria cocos by using a multifunctional extraction tank, and adding water for decocting for 3 times;
s103, filtering, combining filtrates, concentrating the filtrate into 1.25-1.28 fluid extract, placing the obtained fluid extract in a reduced pressure drying oven for reduced pressure drying, and crushing the dried dry extract and sieving by a 80-mesh sieve to obtain dry extract powder;
s104, mixing the obtained dry paste powder with the weighed antler powder to obtain mixed powder; adding 90% ethanol into the total mixed powder to obtain uniform and appropriate soft material, and granulating;
s105, sieving with a 20-mesh sieve, drying at 60-65 ℃ to obtain dry particles, grading the prepared dry particles with the 20-mesh sieve, uniformly mixing, and subpackaging to obtain the anti-fatigue health-care product.
The decoction provided by the embodiment of the invention comprises the following steps: adding 7 times of water for each decoction, and decocting for 1.5 hr each time.
The technical solution of the present invention is further described with reference to the following specific embodiments.
Example 1:
the main raw materials of the invention are Changbai mountain black ant extract, antler powder, yam, radix astragali and tuckahoe. Changbai mountain is an ideal region for the growth of various wild animals and plants, wherein Changbai mountain black ants are widely distributed and have rich resources, and are traditional characteristic resources of Jilin province. Previous research proves that ants contain rich vitamins
The micro element rope and amino acid essential to human body, and has higher medicinal and Sichuan values and health care functions. The Changbai mountain black ant has higher content than other ants. The astragalus root, the Chinese yam and the tuckahoe have obvious promotion effect on the antibody generating function of normal organisms. The existing research shows that the Changbai mountain black ants and the pilose antler both have the anti-fatigue function, and according to the theory of traditional Chinese medicine, the five medicines are applied in a matching way, and have the functions of reinforcing and reducing discharge, and reinforcing and attacking, and the formula is reasonable, scientific and effective. Therefore, the main raw materials such as Changbai mountain black ants, antler powder and the like are mixed with available auxiliary materials, the anti-fatigue effect of the product and the factors influencing the stability of the product are explored, the preparation process and the parameter range are optimized, and the development and the transformation of the health care product are carried out.
The specific implementation content of the invention is as follows:
experiments verify that the anti-fatigue effect of the mixture of Changbai mountain black ants, antler powder, Chinese yam, radix astragali and tuckahoe is as follows: and the optimal use concentration is obtained by performing a fatigue test on a sub-health fatigue animal model to perform behavioral observation. The effect is judged by detecting the anti-fatigue biochemical index in the body of the mouse after the test, and the effective period of the medicine is judged by the anti-fatigue biochemical index 7,14 days and 21 days after the medicine is taken.
Screening a reasonable formula: the research product takes Changbai mountain black ants as main raw materials, and has the function of fatigue resistance after reasonable process processing.
The production process research: extraction: taking the medicinal materials according to the formula proportion, extracting with a multifunctional extraction tank, decocting with water for 3 times, filtering, and mixing filtrates. Concentration: concentrating the filtrate to relative density
And (6) obtaining clear paste. Drying under reduced pressure and crushing: crushing the dry paste and sieving the crushed dry paste by a 80-mesh sieve; mixing the obtained dry paste powder with cornu cervi pantotrichum, and granulating: adding 90% ethanol into the total mixed powder to obtain uniform and suitable soft material, granulating, sieving with 20 mesh sieve, and drying at drying temperature
And (4) granulating the prepared dry granules by using a 20-mesh sieve, uniformly mixing and subpackaging.
And (3) product standard and inspection method preparation: according to the modern physical and chemical research related data of the components of the formula, a feasible detection method is selected or the detection is carried out according to the national regulation.
And (3) carrying out toxicology and functional evaluation of the product: comprises checking the formula, checking the production process, sanitary detection, toxicity test and the like.
The method comprises the following steps:
1. mixing Changbai mountain black ant powder with cornu Cervi Pantotrichum powder, rhizoma Dioscoreae, radix astragali, and Poria, and making into capsule containing Formica Fusca lg,3g, and 5g,
2. the 120-day-old fatigue-type sub-healthy male mouse model is divided into a blank group, a model group and 5 groups with 7,14 and 21 days of physical strength recovery. Gavage with different dosages of Formica fusca 0.2ml/10g for 30 days, and observing different concentrations and time gradient data by swimming under load for statistical analysis.
3. And (4) carrying out statistical analysis on biochemical indexes of fatigue on the blood examination side of the eyeball of the mouse, such as lactic acid, urea nitrogen, superoxide dismutase, catalase, lactate dehydrogenase and the like after the load bearing experiment in the last day D0,7,14 and 21 days.
4. Description of the production process: taking the raw materials according to the formula proportion, extracting with a multifunctional extraction tank, decocting with water for 3 times, adding 7 times of water each time, decocting for 1.5 times/time, filtering, and mixing filtrates. Concentration: concentrating the filtrate to obtain fluid extract with relative density of 1.25-1.28. Drying under reduced pressure: drying the fluid extract in a drying curtain under reduced pressure. Crushing: pulverizing the dry extract, and sieving with 80 mesh sieve to obtain dry extract powder. Mixing: mixing the dry extract powder and cornu Cervi Pantotrichum powder to obtain total mixed powder. And (3) granulating: adding 90% ethanol into the total mixed powder to obtain uniform and appropriate soft material, granulating,
the screen mesh is 20 meshes, and the drying is carried out at the temperature of 60-65 ℃: and (4) granulating the prepared dry granules by using a 20-mesh sieve, and uniformly mixing for later use. Subpackaging 0.85 g/grain and 60 grains/bottle.
5. And (3) toxicology and functional evaluation of products: inspecting the formula, inspecting the production process, detecting the sanitation, testing the toxicity, testing the stability and the like.
6. The health product capsule prepared by the invention has bright and beautiful appearance, no improper bitter odor and convenient taking; the functional component index total protein content of the prepared health-care product is more than 20mg/100g, the functional component index astragaloside is more than 20mg/100g, and the microorganism index reaches the general standard of health-care (functional) food.
The above description is only for the purpose of illustrating the present invention and the appended claims are not to be construed as limiting the scope of the invention, which is intended to cover all modifications, equivalents and improvements that are within the spirit and scope of the invention as defined by the appended claims.
Claims (10)
1. An anti-fatigue traditional Chinese medicine health product is characterized by comprising Changbai mountain black ant extract, antler powder, Chinese yam, radix astragali and poria cocos according to parts by mass.
2. The anti-fatigue traditional Chinese medicine health product as claimed in claim 1, wherein the anti-fatigue traditional Chinese medicine health product comprises the following components in parts by mass:
10g of black ants, 6g of antler powder, 15g of Chinese yam, 10g of radix astragali and 10g of poria cocos.
3. The preparation method of the anti-fatigue traditional Chinese medicine health product as claimed in claim 1, wherein the preparation method of the anti-fatigue traditional Chinese medicine health product comprises the following steps:
weighing Changbai mountain black ant extract, Chinese yam, radix astragali and tuckahoe in proportion, extracting, filtering, concentrating and crushing to prepare dry paste powder; mixing the prepared dry extract powder with cornu Cervi Pantotrichum powder, and granulating.
4. The method for preparing the anti-fatigue traditional Chinese medicine health product as claimed in claim 3, wherein the method for preparing the anti-fatigue traditional Chinese medicine health product comprises the following steps:
weighing Changbai mountain black ant extract, antler powder, Chinese yam, radix astragali and poria cocos according to a proportion;
step two, extracting the weighed Changbai mountain black ant extract, the yam, the radix astragali and the tuckahoe by a multifunctional extraction tank, and adding water for decocting for 3 times;
filtering, combining the filtrates, concentrating, drying under reduced pressure, and pulverizing to obtain dry extract powder;
step four, mixing the obtained dry paste powder with the weighed antler powder to obtain mixed powder; granulating the mixed powder;
and fifthly, sieving and drying to obtain dry granules, grading the prepared dry granules by using a 20-mesh sieve, uniformly mixing and subpackaging to obtain the anti-fatigue health-care product.
5. The method for preparing the anti-fatigue traditional Chinese medicine health product as claimed in claim 4, wherein in the second step, the decoction comprises: adding 7 times of water for each decoction, and decocting for 1.5 hr each time.
6. The method for preparing an anti-fatigue health product of traditional Chinese medicine as claimed in claim 4, wherein in step two, the concentration comprises: concentrating the filtrate to obtain fluid extract of 1.25-1.28.
7. The method for preparing the anti-fatigue traditional Chinese medicine health product as claimed in claim 4, wherein in the second step and the third step, the drying under reduced pressure comprises: and placing the obtained clear paste in a reduced pressure drying oven for reduced pressure drying.
8. The method for preparing the anti-fatigue traditional Chinese medicine health product as claimed in claim 4, wherein in the second step and the third step, the crushing comprises: pulverizing the dried dry extract, and sieving with 80 mesh sieve.
9. The method for preparing an anti-fatigue health product of traditional Chinese medicine according to claim 4, wherein in the second step, in the fourth step, the granulating of the mixed powder comprises: adding 90% ethanol into the total mixed powder to obtain uniform and appropriate soft material, and granulating.
10. The method for preparing the anti-fatigue traditional Chinese medicine health product as claimed in claim 4, wherein in step two, in step five, the sieving comprises: sieving with 20 mesh sieve; in the second step, in the fifth step, the drying includes: the drying temperature is 60-65 ℃.
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Application publication date: 20210924 |