CN104435352A - Health medicine for maintaining body and preparation method of health medicine - Google Patents
Health medicine for maintaining body and preparation method of health medicine Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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Abstract
The invention relates to a health medicine for maintaining body. The medicine is prepared from the following components in parts by weight: silky ant, hericium erinaceus, codonopsis pilosula, astragalus membranaceus, angelica sinensis, poria cocos and lycium barbarum. The preparation method comprises the following steps: extracting silky ant protein from silky ants; decocting hericium erinaceus, codonopsis pilosula, astragalus membranaceus, angelica sinensis, poria cocos and lycium barbarum with water; filtering, freezing and drying the filtrate in vacuum; mixing the silky ant protein and the decoction extract of the traditional Chinese medicinal materials; adding honey to prepare pills which are the health medicine for maintaining body. The health medicine is rich in nutrition, and has the effects of reinforcing body constitution, nourishing blood, moistening dryness, lowering blood pressure and relieving fatigue.
Description
technical fieldthe invention belongs to health product technology field, relate to a kind of health care medicine and preparation method thereof.
Background technology
In modern society, due to the change of environment, work pressure, dietary habit, lack exercise etc., cause the body immunity of people to decline, fatiguability, resistance against diseases are poor.Along with the raising gradually of people's quality of life, the enhancing day by day of consumption idea and health perception, for health product industry brings huge market development space.
Traditional eating method of Formica fusca as made tea, steeping in wine, Baoshang, pulverizing etc., absorbance is extremely low.The patient of many ant healths, disease therapy, to last, although do not know and eaten a large amount of Formica fuscas, absorption be only a little part.Most efficient compositions all " is worn intestinal and crosses ", wastes surprising! Also understandable conventional Formica fusca is used as medicine, and produces little effect.
Summary of the invention
The present invention, for solving the problem, provides a kind of life enhancement medicine and preparation method thereof.
The present invention is the technical scheme solving the problems of the technologies described above employing:
A kind of life enhancement medicine, comprises by weight:
Formica fusca 15-30 part
Hericium erinaceus (Bull. Ex Fr.) Pers. 10-20 part
Radix Codonopsis 6-15 part
Radix Astragali 6-15 part
Radix Angelicae Sinensis 5-12 part
Poria 10-20 part
Fructus Lycii 6-15 part.
Preferably, described medicine is tablet, pill, powder, capsule, granule or solution form.
Further preferably, said medicine is pill.
Prepare a method for above-mentioned health care medicine, comprise the following steps:
(1) Formica fusca protein extraction
Dry: Formica fusca puts into 45 DEG C of constant pressure and dry casees, after dry 4 h, pulverize, cross 60 order analysis sieves;
Defat: with the fat in the Formica fusca of extraction element removing drying, thus obtain defat Formica fusca;
Precipitation: be made into the rare HCl of 1.46 mol/L with the analytical pure HCl of 36%-38%.In above-mentioned filtrate, limit drips the stirring of dilute hydrochloric acid limit, regulating pH to occurring a large amount of black precipitate, leaving standstill, obtaining protein crude product;
Desalination: the protein semifinished product obtained is put into the washing of centrifuge deionized water, centrifugal, repeat, several times to supernatant colorless and odorless, to get multilamellar filter-cloth filtering;
Oven dry, porphyrize: the Ant Protein after filtering is placed in evaporating dish, puts into electric drying oven with forced convection 45 DEG C of drying 2 h, take out weighing after cooling, porphyrize, obtain Ant Protein;
(2) Chinese herbal medicine extracting
Hericium erinaceus (Bull. Ex Fr.) Pers., Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Poria, Fructus Lycii are added the water of 8 times of weight, decoct 2 times, merge 2 decocting liquids, filter, filter vacuum lyophilization;
(3) Formica fusca albumen and Chinese herbal medicine extract are mixed.
Preferably, extraction element can be apparatus,Soxhlet's.
Preferably, centrifugal speed is 4000 RPM/min, time be 15 min.
Preferably, decocting time is each 2 hours.
Preferably, add Mel in the mixture and make pill.
Formica fusca is the Formica fusca uniquely having medicine, eat dual-purpose value through Ministry of Public Health approval, containing 70 multiple nutrients compositions in its body, containing the protein of 42-67%, and 28 kinds of free amino acids (comprising 8 seed amino acids that human body is necessary); Containing vitamin B1, B2, B12, C, D, E etc.; 20 various trace elements such as calcic, ferrum, phosphorus, manganese, selenium, zinc, be particularly described as " life spark ' content of zinc is the abundantest, and every kilogram reaches 120-198 milligram containing zinc; Containing triterpenoid compound, formic acid, adenosine triphosphate (ATP) and the various bioactivators such as cursive script formaldehyde, interleukin II that manually cannot synthesize, its content comes out at the top in 1,000,000 kinds of animal and plant.Major function has enhancing immunity, antiviral, parkinsonism, immunity moderation.
The nutritional labeling of Hericium erinaceus (Bull. Ex Fr.) Pers. is very high, and every hectogram, containing 26.3 grams, protein, is two times of Lentinus Edodes.It contains amino acid/11 7 kinds, wherein needed by human body account for 8 kinds.Fatty 4.2 grams of every hectogram Hericium erinaceus (Bull. Ex Fr.) Pers., is genuine high protein, low-fat food, is also rich in various vitamin and inorganic salt in addition.Hericium erinaceus (Bull. Ex Fr.) Pers. has appetite stimulator, strengthens gastric mucosal barrier function, improves lymhocyte transformation rate, promotes the effects such as leukocyte.Therefore the immunocompetence of human body raising to disease can be made.Hedgehog hydnum or good nourishing food, have good efficacy to neurasthenia, digestive tract ulcer.
Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effects such as hemopoietic function.In addition castering action is had to the leukopenia that chemotherapy radiotherapy causes.
The Radix Astragali is containing the various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper.The Radix Astragali have reduce blood viscosity, reduce thrombosis, reduce blood pressure, cardioprotection, two-ways regulation blood glucose, free radical resisting damage, defying age, anti-hypoxia, antitumor, the effect of enhancing human body immunity power, can be used to treat the disease such as heart disease, hypertension, diabetes.The Radix Astragali can also blood vessel dilating, improves cutaneous circulation and nutriture, therefore effective to chronic ulcer disunion person of a specified duration.It can also eliminate the albuminuria of nephritis patient, the liver protecting, prevents hepatic glycogen from reducing.
Radix Angelicae Sinensis, mainly containing sucrose, several amino acids, volatile oil and n-butene, lactone, nicotinic acid, ferulic acid and half terpenoid, also contains VitAVitE, volatile oil, arginine and several mineral materials.Have enrich blood, Adjust-blood lipid, blood pressure lowering, enhancing immunity, antiinflammatory, protect the liver, the effect such as radioprotective, antioxidation and scavenging free radicals.In addition, uterine smooth muscle can also be regulated.
Poria contains the materials such as pachyman, pachymic acid, fatty acid, lecithin, adenine, protease and triterpenes, also containing mineral such as potassium, calcium, magnesium, phosphorus, ferrum, sulfur and silicon dioxide.There is inducing diuresis to remove edema, improve the effect such as body immunity, blood pressure lowering.
Fructus Lycii contains abundant carotene, betanin, vitamin A, B1, B2, C and calcium, ferrum etc.Have improving eyesight, improve immunity of organisms, fall three-hypers effects such as (regulate blood glucose, reduce blood pressure, prevent and treat the diseases such as hypertension, heart disease, arteriosclerosis).
Beneficial effect of the present invention is: the present invention is nutritious, has health invigorating, nourishing blood for moistening dryness, reduces blood pressure, effect of fatigue alleviating.
Detailed description of the invention
embodiment 1
A kind of life enhancement medicine, comprises by weight:
Formica fusca 20 parts
Hericium erinaceus (Bull. Ex Fr.) Pers. 14 parts
Radix Codonopsis 9 parts
The Radix Astragali 9 parts
Radix Angelicae Sinensis 7 parts
14 parts, Poria
Fructus Lycii 9 parts.
Prepare a method for above-mentioned health care medicine, comprise the following steps:
(1) Formica fusca protein extraction
Dry: Formica fusca puts into 45 DEG C of constant pressure and dry casees, after dry 4 h, pulverize, cross 60 order analysis sieves;
Defat: extract the fat in the Formica fusca of removing drying with apparatus,Soxhlet's, thus obtain defat Formica fusca;
Precipitation: be made into the rare HCl of 1.46 mol/L with the analytical pure HCl of 36%-38%.In above-mentioned filtrate, limit drips the stirring of dilute hydrochloric acid limit, regulating pH to occurring a large amount of black precipitate, leaving standstill, obtaining protein crude product;
Desalination: the protein semifinished product obtained is put into centrifuge deionized water centrifugal water and washes, centrifugal speed is 4000 RPM/min, time 15 min, repeats, several times to supernatant colorless and odorless, to get multilamellar filter-cloth filtering;
Oven dry, porphyrize: the Ant Protein after filtering is placed in evaporating dish, puts into electric drying oven with forced convection 45 DEG C of drying 2 h, take out weighing after cooling, porphyrize, obtain Ant Protein;
(2) Chinese herbal medicine extracting
Hericium erinaceus (Bull. Ex Fr.) Pers., Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Poria, Fructus Lycii are added the water of 8 times of weight, decoct 2 times, each 2 hours, merge 2 decocting liquids, filter, filter vacuum lyophilization;
(3) Formica fusca albumen and Chinese herbal medicine extract are mixed, add processed with honey and become pill.
embodiment 2
A kind of life enhancement medicine, comprises by weight:
Formica fusca 15 parts
Hericium erinaceus (Bull. Ex Fr.) Pers. 10 parts
Radix Codonopsis 6 parts
The Radix Astragali 6 parts
Radix Angelicae Sinensis 5 parts
10 parts, Poria
Fructus Lycii 6 parts.
Prepare a method for above-mentioned health care medicine, comprise the following steps:
(1) Formica fusca protein extraction
Dry: Formica fusca puts into 45 DEG C of constant pressure and dry casees, after dry 4 h, pulverize, cross 60 order analysis sieves;
Defat: extract the fat in the Formica fusca of removing drying with apparatus,Soxhlet's, thus obtain defat Formica fusca;
Precipitation: be made into the rare HCl of 1.46 mol/L with the analytical pure HCl of 36%-38%.In above-mentioned filtrate, limit drips the stirring of dilute hydrochloric acid limit, regulating pH to occurring a large amount of black precipitate, leaving standstill, obtaining protein crude product;
Desalination: the protein semifinished product obtained is put into centrifuge deionized water centrifugal water and washes, centrifugal speed is 4000 RPM/min, time 15 min, repeats, several times to supernatant colorless and odorless, to get multilamellar filter-cloth filtering;
Oven dry, porphyrize: the Ant Protein after filtering is placed in evaporating dish, puts into electric drying oven with forced convection 45 DEG C of drying 2 h, take out weighing after cooling, porphyrize, obtain Ant Protein;
(2) Chinese herbal medicine extracting
Hericium erinaceus (Bull. Ex Fr.) Pers., Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Poria, Fructus Lycii are added the water of 8 times of weight, decoct 2 times, each 2 hours, merge 2 decocting liquids, filter, filter vacuum lyophilization;
(3) Formica fusca albumen and Chinese herbal medicine extract are mixed, add processed with honey and become pill.
embodiment 3
A kind of life enhancement medicine, comprises by weight:
Formica fusca 30 parts
Hericium erinaceus (Bull. Ex Fr.) Pers. 20 parts
Radix Codonopsis 15 parts
The Radix Astragali 15 parts
Radix Angelicae Sinensis 12 parts
20 parts, Poria
Fructus Lycii 15 parts.
Prepare a method for above-mentioned health care medicine, comprise the following steps:
(1) Formica fusca protein extraction
Dry: Formica fusca puts into 45 DEG C of constant pressure and dry casees, after dry 4 h, pulverize, cross 60 order analysis sieves;
Defat: extract the fat in the Formica fusca of removing drying with apparatus,Soxhlet's, thus obtain defat Formica fusca;
Precipitation: be made into the rare HCl of 1.46 mol/L with the analytical pure HCl of 36%-38%.In above-mentioned filtrate, limit drips the stirring of dilute hydrochloric acid limit, regulating pH to occurring a large amount of black precipitate, leaving standstill, obtaining protein crude product;
Desalination: the protein semifinished product obtained is put into centrifuge deionized water centrifugal water and washes, centrifugal speed is 4000 RPM/min, time 15 min, repeats, several times to supernatant colorless and odorless, to get multilamellar filter-cloth filtering;
Oven dry, porphyrize: the Ant Protein after filtering is placed in evaporating dish, puts into electric drying oven with forced convection 45 DEG C of drying 2 h, take out weighing after cooling, porphyrize, obtain Ant Protein;
(2) Chinese herbal medicine extracting
Hericium erinaceus (Bull. Ex Fr.) Pers., Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Poria, Fructus Lycii are added the water of 8 times of weight, decoct 2 times, each 2 hours, merge 2 decocting liquids, filter, filter vacuum lyophilization;
(3) Formica fusca albumen and Chinese herbal medicine extract are mixed, add processed with honey and become pill.
embodiment 4
A kind of life enhancement medicine, comprises by weight:
Formica fusca 25 parts
Hericium erinaceus (Bull. Ex Fr.) Pers. 17 parts
Radix Codonopsis 12 parts
The Radix Astragali 12 parts
Radix Angelicae Sinensis 10 parts
17 parts, Poria
Fructus Lycii 12 parts.
Prepare a method for above-mentioned health care medicine, comprise the following steps:
(1) Formica fusca protein extraction
Dry: Formica fusca puts into 45 DEG C of constant pressure and dry casees, after dry 4 h, pulverize, cross 60 order analysis sieves;
Defat: extract the fat in the Formica fusca of removing drying with apparatus,Soxhlet's, thus obtain defat Formica fusca;
Precipitation: be made into the rare HCl of 1.46 mol/L with the analytical pure HCl of 36%-38%.In above-mentioned filtrate, limit drips the stirring of dilute hydrochloric acid limit, regulating pH to occurring a large amount of black precipitate, leaving standstill, obtaining protein crude product;
Desalination: the protein semifinished product obtained is put into centrifuge deionized water centrifugal water and washes, centrifugal speed is 4000 RPM/min, time 15 min, repeats, several times to supernatant colorless and odorless, to get multilamellar filter-cloth filtering;
Oven dry, porphyrize: the Ant Protein after filtering is placed in evaporating dish, puts into electric drying oven with forced convection 45 DEG C of drying 2 h, take out weighing after cooling, porphyrize, obtain Ant Protein;
(2) Chinese herbal medicine extracting
Hericium erinaceus (Bull. Ex Fr.) Pers., Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Poria, Fructus Lycii are added the water of 8 times of weight, decoct 2 times, each 2 hours, merge 2 decocting liquids, filter, filter vacuum lyophilization;
(3) Formica fusca albumen and Chinese herbal medicine extract are mixed, add processed with honey and become pill.
Claims (8)
1. a life enhancement medicine, comprises by weight:
Formica fusca 15-30 part
Hericium erinaceus (Bull. Ex Fr.) Pers. 10-20 part
Radix Codonopsis 6-15 part
Radix Astragali 6-15 part
Radix Angelicae Sinensis 5-12 part
Poria 10-20 part
Fructus Lycii 6-15 part.
2. medicine according to claim 1, is characterized in that, described medicine is tablet, pill, powder, capsule, granule or solution form.
3. medicine according to claim 2, is characterized in that, described medicine is pill.
4. prepare a method for the medicine according to any one of the claims, comprise the following steps:
(1) Formica fusca protein extraction
Dry: Formica fusca puts into 45 DEG C of constant pressure and dry casees, after dry 4 h, pulverize, cross 60 order analysis sieves;
Defat: with the fat in the Formica fusca of extraction element removing drying, thus obtain defat Formica fusca;
Precipitation: be made into the rare HCl of 1.46 mol/L with the analytical pure HCl of 36%-38%, in above-mentioned filtrate, limit drips the stirring of dilute hydrochloric acid limit, regulating pH to occurring a large amount of black precipitate, leaving standstill, obtaining protein crude product;
Desalination: the protein semifinished product obtained is put into the washing of centrifuge deionized water, centrifugal, repeat, several times to supernatant colorless and odorless, to get multilamellar filter-cloth filtering;
Oven dry, porphyrize: the Ant Protein after filtering is placed in evaporating dish, puts into electric drying oven with forced convection 45 DEG C of drying 2 h, take out weighing after cooling, porphyrize, obtain Ant Protein;
(2) Chinese herbal medicine extracting
Hericium erinaceus (Bull. Ex Fr.) Pers., Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis, Poria, Fructus Lycii are added the water of 8 times of weight, decoct 2 times, merge 2 decocting liquids, filter, filter vacuum lyophilization;
(3) Formica fusca albumen and Chinese herbal medicine extract are mixed.
5. method according to claim 4, is characterized in that, extraction element is apparatus,Soxhlet's.
6. method according to claim 4, is characterized in that, centrifugal speed is 4000 RPM/min, and centrifugation time is 15 min.
7. method according to claim 4, is characterized in that, in step (2), decocting time is each 2 hours.
8. method according to claim 4, is characterized in that, comprises interpolation Mel in the mixture further and makes pill.
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| Application Number | Priority Date | Filing Date | Title |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113424960A (en) * | 2021-08-16 | 2021-09-24 | 吉林大学 | Anti-fatigue traditional Chinese medicine health product and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113424960A (en) * | 2021-08-16 | 2021-09-24 | 吉林大学 | Anti-fatigue traditional Chinese medicine health product and preparation method thereof |
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