CN113424908A - 稳定饮料糖浆中的山梨酸 - Google Patents
稳定饮料糖浆中的山梨酸 Download PDFInfo
- Publication number
- CN113424908A CN113424908A CN202110782224.2A CN202110782224A CN113424908A CN 113424908 A CN113424908 A CN 113424908A CN 202110782224 A CN202110782224 A CN 202110782224A CN 113424908 A CN113424908 A CN 113424908A
- Authority
- CN
- China
- Prior art keywords
- sorbate
- carrier
- powder
- beverage
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013361 beverage Nutrition 0.000 title claims abstract description 102
- 235000020357 syrup Nutrition 0.000 title claims abstract description 86
- 239000006188 syrup Substances 0.000 title claims abstract description 86
- 230000000087 stabilizing effect Effects 0.000 title claims abstract description 25
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 title description 67
- 229940075582 sorbic acid Drugs 0.000 title description 67
- 235000010199 sorbic acid Nutrition 0.000 title description 67
- 239000004334 sorbic acid Substances 0.000 title description 67
- WSWCOQWTEOXDQX-MQQKCMAXSA-M (E,E)-sorbate Chemical compound C\C=C\C=C\C([O-])=O WSWCOQWTEOXDQX-MQQKCMAXSA-M 0.000 claims abstract description 84
- 229940075554 sorbate Drugs 0.000 claims abstract description 81
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 53
- 239000000843 powder Substances 0.000 claims abstract description 47
- 238000000034 method Methods 0.000 claims abstract description 35
- 238000004519 manufacturing process Methods 0.000 claims abstract description 12
- 238000001694 spray drying Methods 0.000 claims abstract description 9
- 239000000796 flavoring agent Substances 0.000 claims description 25
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical group [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 24
- 239000004302 potassium sorbate Substances 0.000 claims description 24
- 235000010241 potassium sorbate Nutrition 0.000 claims description 24
- 229940069338 potassium sorbate Drugs 0.000 claims description 24
- 235000003599 food sweetener Nutrition 0.000 claims description 22
- 239000003765 sweetening agent Substances 0.000 claims description 22
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 18
- 235000019634 flavors Nutrition 0.000 claims description 18
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 16
- 239000004615 ingredient Substances 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 14
- 235000019982 sodium hexametaphosphate Nutrition 0.000 claims description 13
- 239000002253 acid Substances 0.000 claims description 10
- RPYRMTHVSUWHSV-CUZJHZIBSA-N rebaudioside D Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RPYRMTHVSUWHSV-CUZJHZIBSA-N 0.000 claims description 10
- 150000003839 salts Chemical class 0.000 claims description 10
- 229920002774 Maltodextrin Polymers 0.000 claims description 8
- 239000005913 Maltodextrin Substances 0.000 claims description 8
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 8
- 229940035034 maltodextrin Drugs 0.000 claims description 8
- 229920000084 Gum arabic Polymers 0.000 claims description 6
- 235000010489 acacia gum Nutrition 0.000 claims description 6
- 239000000205 acacia gum Substances 0.000 claims description 6
- 235000019202 steviosides Nutrition 0.000 claims description 6
- 239000001512 FEMA 4601 Substances 0.000 claims description 5
- HELXLJCILKEWJH-SEAGSNCFSA-N Rebaudioside A Natural products O=C(O[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@@]1(C)[C@@H]2[C@](C)([C@H]3[C@@]4(CC(=C)[C@@](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@H](O)[C@@H](CO)O5)(C4)CC3)CC2)CCC1 HELXLJCILKEWJH-SEAGSNCFSA-N 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 5
- 239000004383 Steviol glycoside Chemical class 0.000 claims description 5
- HELXLJCILKEWJH-UHFFFAOYSA-N entered according to Sigma 01432 Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC(C1OC2C(C(O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O HELXLJCILKEWJH-UHFFFAOYSA-N 0.000 claims description 5
- 239000001508 potassium citrate Substances 0.000 claims description 5
- 229960002635 potassium citrate Drugs 0.000 claims description 5
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims description 5
- 235000011082 potassium citrates Nutrition 0.000 claims description 5
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 claims description 5
- 235000019203 rebaudioside A Nutrition 0.000 claims description 5
- 239000008107 starch Substances 0.000 claims description 5
- 235000019698 starch Nutrition 0.000 claims description 5
- 235000019411 steviol glycoside Nutrition 0.000 claims description 5
- 229930182488 steviol glycoside Chemical class 0.000 claims description 5
- 150000008144 steviol glycosides Chemical class 0.000 claims description 5
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 4
- 229920000881 Modified starch Polymers 0.000 claims description 4
- 239000004368 Modified starch Substances 0.000 claims description 4
- 229940072056 alginate Drugs 0.000 claims description 4
- 235000010443 alginic acid Nutrition 0.000 claims description 4
- 229920000615 alginic acid Polymers 0.000 claims description 4
- 239000000420 anogeissus latifolia wall. gum Substances 0.000 claims description 4
- 235000010418 carrageenan Nutrition 0.000 claims description 4
- 239000000679 carrageenan Substances 0.000 claims description 4
- 229920001525 carrageenan Polymers 0.000 claims description 4
- 229940113118 carrageenan Drugs 0.000 claims description 4
- 239000001913 cellulose Substances 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 4
- 235000010980 cellulose Nutrition 0.000 claims description 4
- 150000004676 glycans Chemical class 0.000 claims description 4
- 235000019314 gum ghatti Nutrition 0.000 claims description 4
- 150000007522 mineralic acids Chemical class 0.000 claims description 4
- 235000019426 modified starch Nutrition 0.000 claims description 4
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims description 4
- 235000019796 monopotassium phosphate Nutrition 0.000 claims description 4
- 150000007524 organic acids Chemical class 0.000 claims description 4
- 239000001814 pectin Substances 0.000 claims description 4
- 235000010987 pectin Nutrition 0.000 claims description 4
- 229920001277 pectin Polymers 0.000 claims description 4
- 229920001282 polysaccharide Chemical class 0.000 claims description 4
- 239000005017 polysaccharide Chemical class 0.000 claims description 4
- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 claims description 4
- 239000001433 sodium tartrate Substances 0.000 claims description 4
- 229960002167 sodium tartrate Drugs 0.000 claims description 4
- 235000011004 sodium tartrates Nutrition 0.000 claims description 4
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 4
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 claims description 3
- LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims description 3
- 241000978776 Senegalia senegal Species 0.000 claims 2
- 239000000243 solution Substances 0.000 description 32
- 239000000203 mixture Substances 0.000 description 16
- 239000003755 preservative agent Substances 0.000 description 16
- -1 flocs Substances 0.000 description 13
- 239000000463 material Substances 0.000 description 12
- 239000007962 solid dispersion Substances 0.000 description 11
- 150000001875 compounds Chemical class 0.000 description 10
- 239000007921 spray Substances 0.000 description 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- 239000002245 particle Substances 0.000 description 9
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 8
- 238000011084 recovery Methods 0.000 description 8
- 239000006185 dispersion Substances 0.000 description 7
- 150000007513 acids Chemical class 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 239000002244 precipitate Substances 0.000 description 6
- 238000001556 precipitation Methods 0.000 description 6
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 description 6
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 6
- 235000008504 concentrate Nutrition 0.000 description 5
- 235000013355 food flavoring agent Nutrition 0.000 description 5
- 230000002335 preservative effect Effects 0.000 description 5
- 239000004094 surface-active agent Substances 0.000 description 5
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 4
- 244000215068 Acacia senegal Species 0.000 description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- 235000010357 aspartame Nutrition 0.000 description 4
- 235000014171 carbonated beverage Nutrition 0.000 description 4
- 239000012141 concentrate Substances 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- 235000013365 dairy product Nutrition 0.000 description 4
- 229920001542 oligosaccharide Polymers 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 235000013616 tea Nutrition 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 229920000858 Cyclodextrin Polymers 0.000 description 3
- 229930091371 Fructose Natural products 0.000 description 3
- 239000005715 Fructose Substances 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 244000269722 Thea sinensis Species 0.000 description 3
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 235000015165 citric acid Nutrition 0.000 description 3
- 235000013353 coffee beverage Nutrition 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 229960005190 phenylalanine Drugs 0.000 description 3
- 235000021580 ready-to-drink beverage Nutrition 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- 229940074410 trehalose Drugs 0.000 description 3
- RMLYXMMBIZLGAQ-UHFFFAOYSA-N (-)-monatin Natural products C1=CC=C2C(CC(O)(CC(N)C(O)=O)C(O)=O)=CNC2=C1 RMLYXMMBIZLGAQ-UHFFFAOYSA-N 0.000 description 2
- RMLYXMMBIZLGAQ-HZMBPMFUSA-N (2s,4s)-4-amino-2-hydroxy-2-(1h-indol-3-ylmethyl)pentanedioic acid Chemical compound C1=CC=C2C(C[C@](O)(C[C@H](N)C(O)=O)C(O)=O)=CNC2=C1 RMLYXMMBIZLGAQ-HZMBPMFUSA-N 0.000 description 2
- FGOJCPKOOGIRPA-UHFFFAOYSA-N 1-o-tert-butyl 4-o-ethyl 5-oxoazepane-1,4-dicarboxylate Chemical compound CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CCC1=O FGOJCPKOOGIRPA-UHFFFAOYSA-N 0.000 description 2
- 244000144725 Amygdalus communis Species 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 2
- 235000005979 Citrus limon Nutrition 0.000 description 2
- 244000131522 Citrus pyriformis Species 0.000 description 2
- 241001672694 Citrus reticulata Species 0.000 description 2
- 240000007154 Coffea arabica Species 0.000 description 2
- 235000016795 Cola Nutrition 0.000 description 2
- 235000011824 Cola pachycarpa Nutrition 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 2
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 2
- 244000070406 Malus silvestris Species 0.000 description 2
- PBILBHLAPJTJOT-CQSZACIVSA-N Phyllodulcin Chemical compound C1=C(O)C(OC)=CC=C1[C@@H]1OC(=O)C2=C(O)C=CC=C2C1 PBILBHLAPJTJOT-CQSZACIVSA-N 0.000 description 2
- 235000014441 Prunus serotina Nutrition 0.000 description 2
- 235000011941 Tilia x europaea Nutrition 0.000 description 2
- 240000006909 Tilia x europaea Species 0.000 description 2
- 235000017537 Vaccinium myrtillus Nutrition 0.000 description 2
- 244000078534 Vaccinium myrtillus Species 0.000 description 2
- 238000003916 acid precipitation Methods 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- 235000020224 almond Nutrition 0.000 description 2
- 235000021016 apples Nutrition 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- JOKKBOSZTVHKSH-UHFFFAOYSA-N baiyunoside Natural products CC12CCC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)CO3)O)C(C)(C)C1CCC(C)=C2CCC=1C=COC=1 JOKKBOSZTVHKSH-UHFFFAOYSA-N 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 235000013405 beer Nutrition 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- UWHUTZOCTZJUKC-JKSUJKDBSA-N brazilin Chemical compound C12=CC(O)=C(O)C=C2C[C@]2(O)[C@H]1C1=CC=C(O)C=C1OC2 UWHUTZOCTZJUKC-JKSUJKDBSA-N 0.000 description 2
- UWHUTZOCTZJUKC-CVEARBPZSA-N brazilin Natural products C12=CC(O)=C(O)C=C2C[C@@]2(O)[C@@H]1C1=CC=C(O)C=C1OC2 UWHUTZOCTZJUKC-CVEARBPZSA-N 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 235000020971 citrus fruits Nutrition 0.000 description 2
- 235000016213 coffee Nutrition 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 238000002425 crystallisation Methods 0.000 description 2
- 230000008025 crystallization Effects 0.000 description 2
- 229940109275 cyclamate Drugs 0.000 description 2
- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical compound OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 235000020375 flavoured syrup Nutrition 0.000 description 2
- 150000002453 idose derivatives Chemical class 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000004571 lime Substances 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 150000002482 oligosaccharides Chemical class 0.000 description 2
- 230000020477 pH reduction Effects 0.000 description 2
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 2
- 238000005381 potential energy Methods 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- QSRAJVGDWKFOGU-WBXIDTKBSA-N rebaudioside c Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]1(CC[C@H]2[C@@]3(C)[C@@H]([C@](CCC3)(C)C(=O)O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)CC3)C(=C)C[C@]23C1 QSRAJVGDWKFOGU-WBXIDTKBSA-N 0.000 description 2
- 239000012047 saturated solution Substances 0.000 description 2
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical group [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- WRPAFPPCKSYACJ-ZBYJYCAASA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8r,9r,10s,11r,13r,14s,17r)-17-[(5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2r,3s,4r,5r,6s)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-hydroxy-6-methylheptan-2-yl]-11-hydrox Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H](CCC(C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@@H]3[C@]2(C)CC1)C)C(C)(C)O)[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O WRPAFPPCKSYACJ-ZBYJYCAASA-N 0.000 description 1
- GHBNZZJYBXQAHG-KUVSNLSMSA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8s,9r,10r,11r,13r,14s,17r)-17-[(2r,5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GHBNZZJYBXQAHG-KUVSNLSMSA-N 0.000 description 1
- LGQKSQQRKHFMLI-SJYYZXOBSA-N (2s,3r,4s,5r)-2-[(3r,4r,5r,6r)-4,5,6-trihydroxyoxan-3-yl]oxyoxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)CO[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)OC1 LGQKSQQRKHFMLI-SJYYZXOBSA-N 0.000 description 1
- QZOALWMSYRBZSA-PDSBIMDKSA-N (3r,5r,8r,9r,10r,13s,14r)-3-[(2r,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-10,13-dimethyl-17-[(1s)-1-[(2r,5s,6r)-5-methyl-6-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1C[C@H]2C(=O)C[C@@H]3[C@H]4CCC([C@]4(CC[C@H]3[C@@]2(C)CC1)C)[C@H](C)[C@@H]1O[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](C)CC1)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O QZOALWMSYRBZSA-PDSBIMDKSA-N 0.000 description 1
- NUFKRGBSZPCGQB-FLBSXDLDSA-N (3s)-3-amino-4-oxo-4-[[(2r)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid;pentahydrate Chemical compound O.O.O.O.O.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C NUFKRGBSZPCGQB-FLBSXDLDSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- MSWZFWKMSRAUBD-GASJEMHNSA-N 2-amino-2-deoxy-D-galactopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O MSWZFWKMSRAUBD-GASJEMHNSA-N 0.000 description 1
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 description 1
- MSWZFWKMSRAUBD-CBPJZXOFSA-N 2-amino-2-deoxy-D-mannopyranose Chemical compound N[C@@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-CBPJZXOFSA-N 0.000 description 1
- ASJSAQIRZKANQN-CRCLSJGQSA-N 2-deoxy-D-ribose Chemical compound OC[C@@H](O)[C@@H](O)CC=O ASJSAQIRZKANQN-CRCLSJGQSA-N 0.000 description 1
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 description 1
- JCSJTDYCNQHPRJ-UHFFFAOYSA-N 20-hydroxyecdysone 2,3-acetonide Natural products OC1C(O)C(O)COC1OC1C(O)C(O)C(OC2C(C(O)C(O)OC2)O)OC1 JCSJTDYCNQHPRJ-UHFFFAOYSA-N 0.000 description 1
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- DBTMGCOVALSLOR-UHFFFAOYSA-N 32-alpha-galactosyl-3-alpha-galactosyl-galactose Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(OC2C(C(CO)OC(O)C2O)O)OC(CO)C1O DBTMGCOVALSLOR-UHFFFAOYSA-N 0.000 description 1
- PBILBHLAPJTJOT-UHFFFAOYSA-N 3S-phyllodulcin Natural products C1=C(O)C(OC)=CC=C1C1OC(=O)C2=C(O)C=CC=C2C1 PBILBHLAPJTJOT-UHFFFAOYSA-N 0.000 description 1
- LGQKSQQRKHFMLI-UHFFFAOYSA-N 4-O-beta-D-xylopyranosyl-beta-D-xylopyranose Natural products OC1C(O)C(O)COC1OC1C(O)C(O)C(O)OC1 LGQKSQQRKHFMLI-UHFFFAOYSA-N 0.000 description 1
- PVXPPJIGRGXGCY-TZLCEDOOSA-N 6-O-alpha-D-glucopyranosyl-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)C(O)(CO)O1 PVXPPJIGRGXGCY-TZLCEDOOSA-N 0.000 description 1
- PVXPPJIGRGXGCY-DJHAAKORSA-N 6-O-alpha-D-glucopyranosyl-alpha-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@](O)(CO)O1 PVXPPJIGRGXGCY-DJHAAKORSA-N 0.000 description 1
- ODEHMIGXGLNAKK-OESPXIITSA-N 6-kestotriose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@@H]1[C@@H](O)[C@H](O)[C@](CO)(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1 ODEHMIGXGLNAKK-OESPXIITSA-N 0.000 description 1
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 1
- 235000009434 Actinidia chinensis Nutrition 0.000 description 1
- 235000009436 Actinidia deliciosa Nutrition 0.000 description 1
- 239000004377 Alitame Substances 0.000 description 1
- 229920001450 Alpha-Cyclodextrin Polymers 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 235000011437 Amygdalus communis Nutrition 0.000 description 1
- 244000099147 Ananas comosus Species 0.000 description 1
- 235000007119 Ananas comosus Nutrition 0.000 description 1
- 108010011485 Aspartame Proteins 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 235000018185 Betula X alpestris Nutrition 0.000 description 1
- 235000018212 Betula X uliginosa Nutrition 0.000 description 1
- 235000004936 Bromus mango Nutrition 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- 235000009467 Carica papaya Nutrition 0.000 description 1
- 240000006432 Carica papaya Species 0.000 description 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 235000019743 Choline chloride Nutrition 0.000 description 1
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 240000000560 Citrus x paradisi Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 241001634499 Cola Species 0.000 description 1
- 241000723382 Corylus Species 0.000 description 1
- 235000007466 Corylus avellana Nutrition 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-CUHNMECISA-N D-Cellobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-CUHNMECISA-N 0.000 description 1
- YTBSYETUWUMLBZ-UHFFFAOYSA-N D-Erythrose Natural products OCC(O)C(O)C=O YTBSYETUWUMLBZ-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- WQZGKKKJIJFFOK-CBPJZXOFSA-N D-Gulose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O WQZGKKKJIJFFOK-CBPJZXOFSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- WQZGKKKJIJFFOK-WHZQZERISA-N D-aldose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-WHZQZERISA-N 0.000 description 1
- WQZGKKKJIJFFOK-IVMDWMLBSA-N D-allopyranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@@H]1O WQZGKKKJIJFFOK-IVMDWMLBSA-N 0.000 description 1
- LKDRXBCSQODPBY-JDJSBBGDSA-N D-allulose Chemical compound OCC1(O)OC[C@@H](O)[C@@H](O)[C@H]1O LKDRXBCSQODPBY-JDJSBBGDSA-N 0.000 description 1
- YTBSYETUWUMLBZ-IUYQGCFVSA-N D-erythrose Chemical compound OC[C@@H](O)[C@@H](O)C=O YTBSYETUWUMLBZ-IUYQGCFVSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
- PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 description 1
- RXVWSYJTUUKTEA-UHFFFAOYSA-N D-maltotriose Natural products OC1C(O)C(OC(C(O)CO)C(O)C(O)C=O)OC(CO)C1OC1C(O)C(O)C(O)C(CO)O1 RXVWSYJTUUKTEA-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
- ZAQJHHRNXZUBTE-NQXXGFSBSA-N D-ribulose Chemical compound OC[C@@H](O)[C@@H](O)C(=O)CO ZAQJHHRNXZUBTE-NQXXGFSBSA-N 0.000 description 1
- LKDRXBCSQODPBY-OEXCPVAWSA-N D-tagatose Chemical compound OCC1(O)OC[C@@H](O)[C@H](O)[C@@H]1O LKDRXBCSQODPBY-OEXCPVAWSA-N 0.000 description 1
- ZAQJHHRNXZUBTE-UHFFFAOYSA-N D-threo-2-Pentulose Natural products OCC(O)C(O)C(=O)CO ZAQJHHRNXZUBTE-UHFFFAOYSA-N 0.000 description 1
- YTBSYETUWUMLBZ-QWWZWVQMSA-N D-threose Chemical compound OC[C@@H](O)[C@H](O)C=O YTBSYETUWUMLBZ-QWWZWVQMSA-N 0.000 description 1
- SQNRKWHRVIAKLP-UHFFFAOYSA-N D-xylobiose Natural products O=CC(O)C(O)C(CO)OC1OCC(O)C(O)C1O SQNRKWHRVIAKLP-UHFFFAOYSA-N 0.000 description 1
- ZAQJHHRNXZUBTE-WUJLRWPWSA-N D-xylulose Chemical compound OC[C@@H](O)[C@H](O)C(=O)CO ZAQJHHRNXZUBTE-WUJLRWPWSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- 229930186291 Dulcoside Natural products 0.000 description 1
- AFSDNFLWKVMVRB-UHFFFAOYSA-N Ellagic acid Chemical compound OC1=C(O)C(OC2=O)=C3C4=C2C=C(O)C(O)=C4OC(=O)C3=C1 AFSDNFLWKVMVRB-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004386 Erythritol Substances 0.000 description 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 1
- 206010056474 Erythrosis Diseases 0.000 description 1
- 239000001263 FEMA 3042 Substances 0.000 description 1
- 239000001329 FEMA 3811 Substances 0.000 description 1
- 239000001116 FEMA 4028 Substances 0.000 description 1
- 239000001689 FEMA 4674 Substances 0.000 description 1
- 239000001776 FEMA 4720 Substances 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- HYQNKKAJVPMBDR-HIFRSBDPSA-N Hernandulcin Chemical compound CC(C)=CCC[C@](C)(O)[C@@H]1CCC(C)=CC1=O HYQNKKAJVPMBDR-HIFRSBDPSA-N 0.000 description 1
- HYQNKKAJVPMBDR-UHFFFAOYSA-N Hernandulcin Natural products CC(C)=CCCC(C)(O)C1CCC(C)=CC1=O HYQNKKAJVPMBDR-UHFFFAOYSA-N 0.000 description 1
- LKDRXBCSQODPBY-AMVSKUEXSA-N L-(-)-Sorbose Chemical compound OCC1(O)OC[C@H](O)[C@@H](O)[C@@H]1O LKDRXBCSQODPBY-AMVSKUEXSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VSOAQEOCSA-N L-altropyranose Chemical compound OC[C@@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-VSOAQEOCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 235000014826 Mangifera indica Nutrition 0.000 description 1
- 240000007228 Mangifera indica Species 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 241001072983 Mentha Species 0.000 description 1
- 235000014435 Mentha Nutrition 0.000 description 1
- 235000014749 Mentha crispa Nutrition 0.000 description 1
- 244000078639 Mentha spicata Species 0.000 description 1
- 108050004114 Monellin Proteins 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 239000004384 Neotame Substances 0.000 description 1
- AYRXSINWFIIFAE-UHFFFAOYSA-N O6-alpha-D-Galactopyranosyl-D-galactose Natural products OCC1OC(OCC(O)C(O)C(O)C(O)C=O)C(O)C(O)C1O AYRXSINWFIIFAE-UHFFFAOYSA-N 0.000 description 1
- FSJSODMMIYGSTK-AGJIYOFVSA-N OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC[C@H]3O[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O Chemical compound OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC[C@H]3O[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O FSJSODMMIYGSTK-AGJIYOFVSA-N 0.000 description 1
- QZOALWMSYRBZSA-UHFFFAOYSA-N Osladin Natural products C1CC(C)C(OC2C(C(O)C(O)C(C)O2)O)OC1C(C)C(C1(CCC2C3(C)CC4)C)CCC1C2CC(=O)C3CC4OC1OC(CO)C(O)C(O)C1OC1OC(C)C(O)C(O)C1O QZOALWMSYRBZSA-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- DLUTTXMPJCVUFR-HJCIYZGTSA-N Parillin Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O[C@H]1[C@@H]([C@H](O)[C@@H](O)[C@H](C)O1)O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@@H]1C[C@H]2CC[C@H]3[C@@H]4C[C@H]5[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)CC1)C)[C@@H]([C@]1(OC[C@@H](C)CC1)O5)C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O DLUTTXMPJCVUFR-HJCIYZGTSA-N 0.000 description 1
- 235000000370 Passiflora edulis Nutrition 0.000 description 1
- 244000288157 Passiflora edulis Species 0.000 description 1
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 description 1
- IOUVKUPGCMBWBT-DARKYYSBSA-N Phloridzin Natural products O[C@H]1[C@@H](O)[C@H](O)[C@H](CO)O[C@H]1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-DARKYYSBSA-N 0.000 description 1
- OFFJUHSISSNBNT-UHFFFAOYSA-N Polypodoside A Natural products C1CC(C)C(OC2C(C(O)C(O)C(C)O2)O)OC1C(C)C(C1(CCC2C3(C)CC4)C)CCC1C2=CC(=O)C3CC4OC1OC(CO)C(O)C(O)C1OC1OC(C)C(O)C(O)C1O OFFJUHSISSNBNT-UHFFFAOYSA-N 0.000 description 1
- 235000009827 Prunus armeniaca Nutrition 0.000 description 1
- 244000018633 Prunus armeniaca Species 0.000 description 1
- 235000010401 Prunus avium Nutrition 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- 235000006029 Prunus persica var nucipersica Nutrition 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 244000017714 Prunus persica var. nucipersica Species 0.000 description 1
- 240000008296 Prunus serotina Species 0.000 description 1
- 241000508269 Psidium Species 0.000 description 1
- 244000294611 Punica granatum Species 0.000 description 1
- 235000014360 Punica granatum Nutrition 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 description 1
- RLLCWNUIHGPAJY-RYBZXKSASA-N Rebaudioside E Natural products O=C(O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)[C@@H](O)[C@@H](O)[C@H](CO)O1)[C@]1(C)[C@@H]2[C@@](C)([C@@H]3[C@@]4(CC(=C)[C@@](O[C@@H]5[C@@H](O[C@@H]6[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O6)[C@H](O)[C@@H](O)[C@H](CO)O5)(C4)CC3)CC2)CCC1 RLLCWNUIHGPAJY-RYBZXKSASA-N 0.000 description 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 1
- 241001412173 Rubus canescens Species 0.000 description 1
- 240000007651 Rubus glaucus Species 0.000 description 1
- 235000003942 Rubus occidentalis Nutrition 0.000 description 1
- 244000111388 Rubus occidentalis Species 0.000 description 1
- YWPVROCHNBYFTP-UHFFFAOYSA-N Rubusoside Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC1OC(CO)C(O)C(O)C1O YWPVROCHNBYFTP-UHFFFAOYSA-N 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 239000004283 Sodium sorbate Substances 0.000 description 1
- 235000009184 Spondias indica Nutrition 0.000 description 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 description 1
- 241000271567 Struthioniformes Species 0.000 description 1
- 239000004376 Sucralose Substances 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- 244000185386 Thladiantha grosvenorii Species 0.000 description 1
- 229930182647 Trilobatin Natural products 0.000 description 1
- DRQXUCVJDCRJDB-UHFFFAOYSA-N Turanose Natural products OC1C(CO)OC(O)(CO)C1OC1C(O)C(O)C(O)C(CO)O1 DRQXUCVJDCRJDB-UHFFFAOYSA-N 0.000 description 1
- FTNIPWXXIGNQQF-UHFFFAOYSA-N UNPD130147 Natural products OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(OC2C(OC(OC3C(OC(OC4C(OC(O)C(O)C4O)CO)C(O)C3O)CO)C(O)C2O)CO)C(O)C1O FTNIPWXXIGNQQF-UHFFFAOYSA-N 0.000 description 1
- MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 description 1
- LUEWUZLMQUOBSB-UHFFFAOYSA-N UNPD55895 Natural products OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(OC2C(OC(OC3C(OC(O)C(O)C3O)CO)C(O)C2O)CO)C(O)C1O LUEWUZLMQUOBSB-UHFFFAOYSA-N 0.000 description 1
- 235000003095 Vaccinium corymbosum Nutrition 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000263375 Vanilla tahitensis Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 241000219094 Vitaceae Species 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- NKAYJMFKKMUJQU-ZFIFBBNOSA-N [(2s,3r,4r,5r)-3,4-dihydroxy-5-[[(10r,12s,14r)-17-[(2s)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-4,4,7,10,14-pentamethyl-12-[(2r,3r,4s,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-1,2,3,5,6,7,8,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanth Chemical compound O([C@H]1CC2[C@@]3(C)CCC(C(C)(C)C3CC(C2[C@@]2(C)CCC(C21)[C@@]1(C)OC(CC1)C(C)(C)O)C)O[C@H]1[C@@H]([C@@H](O)[C@H](COC(C)=O)O1)O)[C@@H]1O[C@@H](C)[C@H](O)[C@H](O)[C@H]1O NKAYJMFKKMUJQU-ZFIFBBNOSA-N 0.000 description 1
- GCSPRLPXTPMSTL-IBDNADADSA-N [(2s,3r,4s,5s,6r)-2-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)O[C@@]1([C@]2(CO)[C@H]([C@H](O)[C@@H](CO)O2)O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GCSPRLPXTPMSTL-IBDNADADSA-N 0.000 description 1
- ZPVGIKNDGJGLCO-VGAMQAOUSA-N [(2s,3r,4s,5s,6r)-2-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)O[C@@]1([C@]2(CO)[C@H]([C@H](O)[C@@H](CO)O2)O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ZPVGIKNDGJGLCO-VGAMQAOUSA-N 0.000 description 1
- SZYSLWCAWVWFLT-UTGHZIEOSA-N [(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl octadecanoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCCCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O SZYSLWCAWVWFLT-UTGHZIEOSA-N 0.000 description 1
- 101150001446 aceK gene Proteins 0.000 description 1
- 239000000619 acesulfame-K Substances 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 1
- 235000019409 alitame Nutrition 0.000 description 1
- 108010009985 alitame Proteins 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- HDTRYLNUVZCQOY-BTLHAWITSA-N alpha,beta-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-BTLHAWITSA-N 0.000 description 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- SRBFZHDQGSBBOR-STGXQOJASA-N alpha-D-lyxopyranose Chemical compound O[C@@H]1CO[C@H](O)[C@@H](O)[C@H]1O SRBFZHDQGSBBOR-STGXQOJASA-N 0.000 description 1
- HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 description 1
- 229940043377 alpha-cyclodextrin Drugs 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- BNABBHGYYMZMOA-AHIHXIOASA-N alpha-maltoheptaose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)O[C@H](O[C@@H]2[C@H](O[C@H](O[C@@H]3[C@H](O[C@H](O[C@@H]4[C@H](O[C@H](O[C@@H]5[C@H](O[C@H](O[C@@H]6[C@H](O[C@H](O)[C@H](O)[C@H]6O)CO)[C@H](O)[C@H]5O)CO)[C@H](O)[C@H]4O)CO)[C@H](O)[C@H]3O)CO)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O BNABBHGYYMZMOA-AHIHXIOASA-N 0.000 description 1
- OCIBBXPLUVYKCH-QXVNYKTNSA-N alpha-maltohexaose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)O[C@H](O[C@@H]2[C@H](O[C@H](O[C@@H]3[C@H](O[C@H](O[C@@H]4[C@H](O[C@H](O[C@@H]5[C@H](O[C@H](O)[C@H](O)[C@H]5O)CO)[C@H](O)[C@H]4O)CO)[C@H](O)[C@H]3O)CO)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O OCIBBXPLUVYKCH-QXVNYKTNSA-N 0.000 description 1
- 230000003254 anti-foaming effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000000605 aspartame Substances 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
- 229960003438 aspartame Drugs 0.000 description 1
- 235000021015 bananas Nutrition 0.000 description 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 description 1
- FBJQEBRMDXPWNX-CFCQXFMMSA-N beta-D-Glcp-(1->6)-beta-D-Glcp-(1->6)-beta-D-Glcp Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC[C@@H]2[C@H]([C@H](O)[C@@H](O)[C@H](O)O2)O)O1 FBJQEBRMDXPWNX-CFCQXFMMSA-N 0.000 description 1
- JCSJTDYCNQHPRJ-FDVJSPBESA-N beta-D-Xylp-(1->4)-beta-D-Xylp-(1->4)-D-Xylp Chemical compound O[C@@H]1[C@@H](O)[C@H](O)CO[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)C(O)OC2)O)OC1 JCSJTDYCNQHPRJ-FDVJSPBESA-N 0.000 description 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 description 1
- 235000011175 beta-cyclodextrine Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- DLRVVLDZNNYCBX-ZZFZYMBESA-N beta-melibiose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)O1 DLRVVLDZNNYCBX-ZZFZYMBESA-N 0.000 description 1
- 229960004853 betadex Drugs 0.000 description 1
- 235000021014 blueberries Nutrition 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000008366 buffered solution Substances 0.000 description 1
- 235000020289 caffè mocha Nutrition 0.000 description 1
- 239000001201 calcium disodium ethylene diamine tetra-acetate Substances 0.000 description 1
- 235000011188 calcium disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- SHWNNYZBHZIQQV-UHFFFAOYSA-L calcium;disodium;2-[2-[bis(carboxylatomethyl)azaniumyl]ethyl-(carboxylatomethyl)azaniumyl]acetate Chemical compound [Na+].[Na+].[Ca+2].[O-]C(=O)C[NH+](CC([O-])=O)CC[NH+](CC([O-])=O)CC([O-])=O SHWNNYZBHZIQQV-UHFFFAOYSA-L 0.000 description 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 description 1
- 229960003178 choline chloride Drugs 0.000 description 1
- 235000013985 cinnamic acid Nutrition 0.000 description 1
- 229930016911 cinnamic acid Natural products 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 108010010165 curculin Proteins 0.000 description 1
- 229940097362 cyclodextrins Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- 229960000878 docusate sodium Drugs 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- CANAPGLEBDTCAF-UHFFFAOYSA-N dulcoside a Chemical compound OC1C(O)C(O)C(C)OC1OC1C(OC23C(CC4(C2)C(C2(C)C(C(CCC2)(C)C(=O)OC2C(C(O)C(O)C(CO)O2)O)CC4)CC3)=C)OC(CO)C(O)C1O CANAPGLEBDTCAF-UHFFFAOYSA-N 0.000 description 1
- 235000019414 erythritol Nutrition 0.000 description 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 1
- 229940009714 erythritol Drugs 0.000 description 1
- UQPHVQVXLPRNCX-UHFFFAOYSA-N erythrulose Chemical compound OCC(O)C(=O)CO UQPHVQVXLPRNCX-UHFFFAOYSA-N 0.000 description 1
- 229960002737 fructose Drugs 0.000 description 1
- 239000008369 fruit flavor Substances 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- 235000021255 galacto-oligosaccharides Nutrition 0.000 description 1
- 150000003271 galactooligosaccharides Chemical class 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- LRBQNJMCXXYXIU-QWKBTXIPSA-N gallotannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@H]2[C@@H]([C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-QWKBTXIPSA-N 0.000 description 1
- GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 description 1
- 229940080345 gamma-cyclodextrin Drugs 0.000 description 1
- DLRVVLDZNNYCBX-CQUJWQHSSA-N gentiobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-CQUJWQHSSA-N 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 229950006191 gluconic acid Drugs 0.000 description 1
- 235000012209 glucono delta-lactone Nutrition 0.000 description 1
- 229960003681 gluconolactone Drugs 0.000 description 1
- 229960002442 glucosamine Drugs 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 description 1
- 239000001685 glycyrrhizic acid Substances 0.000 description 1
- 229960004949 glycyrrhizic acid Drugs 0.000 description 1
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 description 1
- 235000019410 glycyrrhizin Nutrition 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 235000021021 grapes Nutrition 0.000 description 1
- 229940093915 gynecological organic acid Drugs 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 229960004903 invert sugar Drugs 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000000832 lactitol Substances 0.000 description 1
- 235000010448 lactitol Nutrition 0.000 description 1
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 description 1
- 229960003451 lactitol Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229960000511 lactulose Drugs 0.000 description 1
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 1
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000019223 lemon-lime Nutrition 0.000 description 1
- 235000015122 lemonade Nutrition 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 235000020094 liqueur Nutrition 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 235000010449 maltitol Nutrition 0.000 description 1
- 239000000845 maltitol Substances 0.000 description 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- DJMVHSOAUQHPSN-UHFFFAOYSA-N malto-hexaose Natural products OC1C(O)C(OC(C(O)CO)C(O)C(O)C=O)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(OC4C(C(O)C(O)C(CO)O4)O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 DJMVHSOAUQHPSN-UHFFFAOYSA-N 0.000 description 1
- FJCUPROCOFFUSR-UHFFFAOYSA-N malto-pentaose Natural products OC1C(O)C(OC(C(O)CO)C(O)C(O)C=O)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 FJCUPROCOFFUSR-UHFFFAOYSA-N 0.000 description 1
- UYQJCPNSAVWAFU-UHFFFAOYSA-N malto-tetraose Natural products OC1C(O)C(OC(C(O)CO)C(O)C(O)C=O)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(O)C(CO)O2)O)C(CO)O1 UYQJCPNSAVWAFU-UHFFFAOYSA-N 0.000 description 1
- FJCUPROCOFFUSR-GMMZZHHDSA-N maltopentaose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[C@H](CO)[C@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O[C@@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)[C@@H](CO)O2)O)[C@@H](CO)O1 FJCUPROCOFFUSR-GMMZZHHDSA-N 0.000 description 1
- LUEWUZLMQUOBSB-OUBHKODOSA-N maltotetraose Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O[C@@H]3[C@@H](O[C@@H](O)[C@H](O)[C@H]3O)CO)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-OUBHKODOSA-N 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229960001855 mannitol Drugs 0.000 description 1
- FYGDTMLNYKFZSV-UHFFFAOYSA-N mannotriose Natural products OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(OC2C(OC(O)C(O)C2O)CO)C(O)C1O FYGDTMLNYKFZSV-UHFFFAOYSA-N 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000014569 mints Nutrition 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 229930191869 mogroside IV Natural products 0.000 description 1
- OKGRRPCHOJYNKX-UHFFFAOYSA-N mogroside IV A Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(COC5C(C(O)C(O)C(CO)O5)O)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC(C(C(O)C1O)O)OC1COC1OC(CO)C(O)C(O)C1O OKGRRPCHOJYNKX-UHFFFAOYSA-N 0.000 description 1
- WRPAFPPCKSYACJ-UHFFFAOYSA-N mogroside IV E Natural products C1CC2(C)C3CC=C(C(C(OC4C(C(O)C(O)C(COC5C(C(O)C(O)C(CO)O5)O)O4)O)CC4)(C)C)C4C3(C)C(O)CC2(C)C1C(C)CCC(C(C)(C)O)OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O WRPAFPPCKSYACJ-UHFFFAOYSA-N 0.000 description 1
- TVJXHJAWHUMLLG-UHFFFAOYSA-N mogroside V Natural products CC(CCC(OC1OC(COC2OC(CO)C(O)C(O)C2OC3OC(CO)C(O)C(O)C3O)C(O)C(O)C1O)C(C)(C)O)C4CCC5(C)C6CC=C7C(CCC(OC8OC(COC9OC(CO)C(O)C(O)C9O)C(O)C(O)C8O)C7(C)C)C6(C)C(O)CC45C TVJXHJAWHUMLLG-UHFFFAOYSA-N 0.000 description 1
- ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 description 1
- 229940089953 neohesperidin dihydrochalcone Drugs 0.000 description 1
- 235000010434 neohesperidine DC Nutrition 0.000 description 1
- 235000019412 neotame Nutrition 0.000 description 1
- HLIAVLHNDJUHFG-HOTGVXAUSA-N neotame Chemical compound CC(C)(C)CCN[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-HOTGVXAUSA-N 0.000 description 1
- 108010070257 neotame Proteins 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 239000006174 pH buffer Substances 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- IOUVKUPGCMBWBT-UHFFFAOYSA-N phloridzosid Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-UHFFFAOYSA-N 0.000 description 1
- IOUVKUPGCMBWBT-QNDFHXLGSA-N phlorizin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 IOUVKUPGCMBWBT-QNDFHXLGSA-N 0.000 description 1
- 235000019139 phlorizin Nutrition 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 150000003085 polypodoside A derivatives Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229940068965 polysorbates Drugs 0.000 description 1
- 235000013525 pomegranate juice Nutrition 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 235000021013 raspberries Nutrition 0.000 description 1
- RLLCWNUIHGPAJY-SFUUMPFESA-N rebaudioside E Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RLLCWNUIHGPAJY-SFUUMPFESA-N 0.000 description 1
- QRGRAFPOLJOGRV-UHFFFAOYSA-N rebaudioside F Natural products CC12CCCC(C)(C1CCC34CC(=C)C(CCC23)(C4)OC5OC(CO)C(O)C(OC6OCC(O)C(O)C6O)C5OC7OC(CO)C(O)C(O)C7O)C(=O)OC8OC(CO)C(O)C(O)C8O QRGRAFPOLJOGRV-UHFFFAOYSA-N 0.000 description 1
- HYLAUKAHEAUVFE-AVBZULRRSA-N rebaudioside f Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)CO1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HYLAUKAHEAUVFE-AVBZULRRSA-N 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- YWPVROCHNBYFTP-OSHKXICASA-N rubusoside Chemical compound O([C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YWPVROCHNBYFTP-OSHKXICASA-N 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 229930183111 sapindoside Natural products 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 229930190082 siamenoside Natural products 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- OABYVIYXWMZFFJ-ZUHYDKSRSA-M sodium glycocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 OABYVIYXWMZFFJ-ZUHYDKSRSA-M 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 1
- 235000019250 sodium sorbate Nutrition 0.000 description 1
- ODFAPIRLUPAQCQ-UHFFFAOYSA-M sodium stearoyl lactylate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C([O-])=O ODFAPIRLUPAQCQ-UHFFFAOYSA-M 0.000 description 1
- 229940080352 sodium stearoyl lactylate Drugs 0.000 description 1
- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 description 1
- 229940045946 sodium taurodeoxycholate Drugs 0.000 description 1
- YXHRQQJFKOHLAP-FVCKGWAHSA-M sodium;2-[[(4r)-4-[(3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 YXHRQQJFKOHLAP-FVCKGWAHSA-M 0.000 description 1
- 235000014214 soft drink Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 235000011496 sports drink Nutrition 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- 235000021012 strawberries Nutrition 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 235000015523 tannic acid Nutrition 0.000 description 1
- 229920002258 tannic acid Polymers 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 150000003892 tartrate salts Chemical class 0.000 description 1
- 235000012976 tarts Nutrition 0.000 description 1
- 235000010436 thaumatin Nutrition 0.000 description 1
- 239000000892 thaumatin Substances 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- GSTCPEBQYSOEHV-QNDFHXLGSA-N trilobatin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C=C1O)=CC(O)=C1C(=O)CCC1=CC=C(O)C=C1 GSTCPEBQYSOEHV-QNDFHXLGSA-N 0.000 description 1
- RULSWEULPANCDV-PIXUTMIVSA-N turanose Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](C(=O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RULSWEULPANCDV-PIXUTMIVSA-N 0.000 description 1
- DRSKVOAJKLUMCL-MMUIXFKXSA-N u2n4xkx7hp Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O DRSKVOAJKLUMCL-MMUIXFKXSA-N 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- ABKNGTPZXRUSOI-UHFFFAOYSA-N xylotriose Natural products OCC(OC1OCC(OC2OCC(O)C(O)C2O)C(O)C1O)C(O)C(O)C=O ABKNGTPZXRUSOI-UHFFFAOYSA-N 0.000 description 1
- FYGDTMLNYKFZSV-BYLHFPJWSA-N β-1,4-galactotrioside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-BYLHFPJWSA-N 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/42—Preservation of non-alcoholic beverages
- A23L2/44—Preservation of non-alcoholic beverages by adding preservatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/06—Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Non-Alcoholic Beverages (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Jellies, Jams, And Syrups (AREA)
- Medicinal Preparation (AREA)
Abstract
本发明提供了一种用于制备山梨酸盐粉末的方法，所述方法包括将山梨酸盐溶解在水中，向所述山梨酸盐溶液中添加稳定载体，以及对所述山梨酸盐溶液进行喷雾干燥以形成所述山梨酸盐粉末。所述山梨酸盐粉末在饮料糖浆中是稳定的。
Description
本申请是申请号为201680010884.6的中国专利申请的分案申请。
技术领域
本发明涉及一种用于稳定饮料和饮料糖浆中的山梨酸的方法。具体地，该方法涉及稳定汽水饮料糖浆中的山梨酸。
背景技术
随着消费者对提神饮料的需求不断增加，许多类型的饮料也不断引入。使饮料保持商业流通要求饮料和制备饮料的糖浆在制造后未饮用或使用的情况下可免受变质。
可将饮料保持在能够显著延迟微生物和其它变质剂(诸如，细菌、霉菌和真菌)的活性的条件下。这些条件通常要求例如制冷，直到饮用饮料或糖浆。维持这些条件通常是不可能或不实际的。
用于延迟微生物活性的另一种方法是向饮料中添加防腐剂。许多防腐剂是已知的。但是已知的防腐剂通常具有限制在饮料中使用的缺点。例如，当以足以提供防腐作用的浓度使用防腐剂时，防腐剂可能赋予饮料异味。防腐剂还可能对饮料外观造成不利影响。
在饮料或制备饮料的糖浆的制造或储存条件下，一些防腐剂沉淀出或形成晶体或絮凝物。一些防腐剂可能使饮料变浑浊，这在期望饮料为澄清的情况下是不被消费者接受的。这类现象之所以通常不被消费者接受，不仅是因为存在某些与外观有关的偏见，而且还因为消费者常常将浑浊或微粒形成视为饮料变质。饮料瓶中的絮凝物、晶体或者沉淀物或沉淀样沉积物同样不被消费者接受，因为固体通常口味较差并且呈现出令人不悦的口感(例如，砂砾或多沙的口感)。
饮料通常由被稀释的浓缩物制备。然后立即将饮料提供给消费者，或者对其进行包装以便分配和饮用。浓缩物(常常称为糖浆)便于运送，然后用于在一步法中制备饮料。因此，将所有成分(包括防腐剂)放入糖浆中是方便的。然而，由于糖浆是浓缩的，因而在不产生沉淀的情况下引入溶解度有限的化合物通常是不可能的。
山梨酸广泛地用作食品和饮料中的防腐剂。在饮料中使用山梨酸的常见问题是其溶解度较低。山梨酸在高酸性糖浆中的溶解度较低，例如在60％白利度糖浆中为0.08％。通常，糖浆中的山梨酸水平在0.08％-0.2％的范围内，具体取决于糖水平。山梨酸的溶解度取决于温度。溶解度随温度降低而降低。由于溶解度较低，山梨酸在糖浆中是不稳定的，从而形成沉淀。
美国专利8,697,163、8,691,309、8,563,062和8,414,942以及US 2012/0219679提出了用于稳定糖浆和饮料中的山梨酸以及减少所述山梨酸的沉淀的不同方法。山梨酸水分散体通常在正常糖浆中可稳定24-72小时。
但是山梨酸水分散体的稳定性是有限的，因此通常不会用在需要6个月稳定性的汽水用糖浆中。另外，形成水分散体的过程需要高剪切混合和/或均化。但是由于溶解度较差，所得水分散体的山梨酸浓度较低。因此，希望开发一种包括简单步骤来稳定正常糖浆和汽水用糖浆中的山梨酸的方法。
发明内容
本发明的各方面涉及一种用于稳定饮料糖浆(包括汽水用糖浆)中的山梨酸的方法。
在一个方面，利用固体分散技术并使用载体来稳定山梨酸。
在另一个方面，对山梨酸进行喷雾干燥以形成包括山梨酸和载体的小颗粒。
在另一个方面，向饮料糖浆中添加山梨酸/载体。
具体实施方式
如本文所用，“糖浆”或“饮料糖浆”是向其中添加流体(通常为水)以形成即饮型饮料或“饮料”的饮料前体。通常，糖浆与水的体积比介于1:3至1:8之间，更通常介于1:4和1:5之间。糖浆与水的体积比也表示为“投(throw)”。1:5的比例是饮料工业内常用的比例，称为“1+5投”。
如本文所用，“饮料”是指诸如软饮料、汽水饮料、冷冻即饮型饮料、咖啡饮料、茶饮料、运动饮料和酒精产品的饮料。饮料可以是碳酸化或非碳酸化的。另外，在本发明的某些实施方案中，“饮料”也是指果汁、乳制品和其它非澄清饮料。根据本发明的实施方案的饮料可以是澄清或非澄清的。汽水饮料是指在将饮料分配用于立即饮用时通过将风味糖浆或糖浆浓缩物与碳酸化水混合制备的饮料。
“澄清”是指光学清晰度，即澄清饮料可像水一样澄清。在本发明的优选实施方案中，饮料浓缩物和/或成品饮料是澄清的，如通过HACH浊度计(型号2100AN，美国科罗拉多州洛弗兰德的哈希公司(Model 2100AN,Hach Company,Loveland,Colo.))进行的读取所证实的那样。读数最高至3NTU(浊度单位)被认为是非常澄清的，该值最高至5NTU可被认为是澄清的。当这一读数高至大约6至10NTU时，样品是不澄清的，而是非常轻微混浊或轻微混浊的。在15NTU下，饮料是混浊的。因此，认为浊度不大于5NTU的饮料是澄清饮料，其中该值为6NTU是非常轻微混浊的，而为10NTU是轻微混浊的。
如本文所用，“稳定的”饮料糖浆是指在三天以上、通常一周以上、更通常四周以上、更通常十周以上、最通常二十周以上的时间段内，在室温和低温(<50℉)下不发生相分离(即，无晶体、絮凝物、沉淀物或沉淀)的糖浆。如本文所用，“稳定的”成品饮料是指在四周、通常十周以上、更通常二十周以上、更通常六个月以上的时间段内(即，在成品饮料的典型架藏期内)，在室温下以及40℉、70℉、90℉和110℉下不发生相分离(即，无晶体、絮凝物、沉淀物或沉淀)的澄清饮料。对于基于汽水的糖浆，需要至少六个月的架藏稳定性。
“保存的”饮料在稳定时间段期间不会表现出显著的微生物活性。
如本文通常所用，“水”是质量适于制造饮料且通常经过调理和处理的水。硬度过大可能引起山梨酸沉淀。在本文提供的指导下，技术人员将能够提供质量足够的水。
“流体”意指形成饮料的一部分的水和果汁、乳制品或其它液体饮料产品。例如，可以不提供足以引起山梨酸沉淀的硬度的量添加乳制品组分。在本文提供的指导下，技术人员可以确定乳制品、果汁或其它液体饮料产品的添加是否适用于本发明的实施方案。
为简明起见，当本发明涉及水时，将描述为流体。然而，本文的描述还涉及本文所限定的流体。在本文提供的指导下，技术人员将能够提供适用于形成糖浆的流体。
根据本发明的实施方案制备的饮料和糖浆通常包含水、防腐剂(包括山梨酸)、甜味剂、pH中性化合物、酸和酸性化合物以及风味剂和风味化合物。这些化合物通常包括常见于饮料中的口味调节剂、营养物、着色剂和其它化合物，诸如乳剂、表面活性剂、缓冲剂和抗起泡化合物。
山梨酸和山梨酸盐充当防腐剂。然而，在常见于糖浆中的pH水平下和在糖浆中的足以在由其制备的饮料中提供商业可用的防腐活性的典型山梨酸和/或山梨酸盐浓度下，山梨酸很可能沉淀，除非采取避免沉淀的步骤。山梨酸沉淀对于需要长期储存的汽水用糖浆来说尤其存在问题。
据发现，在制造糖浆和饮料的过程中山梨酸在糖浆中的沉淀可通过以下过程来避免：使用喷雾干燥过程(固体分散)将山梨酸盐或山梨酸盐/山梨酸颗粒分散到惰性亲水性固体载体基质中。然后可将所得颗粒添加到糖浆或饮料组合物中。
首先通过将山梨酸盐溶解在水中来制备山梨酸盐固体分散体。水的温度可为20至99℃，更通常为20至40℃或20至30℃，但最通常为大约室温或20至25℃。溶解的山梨酸盐的量通常用于实现1-60％(w/w)、更通常10-20％(w/w)范围内的浓度。
山梨酸盐可以是任何合适的山梨酸盐，诸如山梨酸钾或山梨酸钠。在具体的方面，使用山梨酸钾。
然后，向溶液中添加至少一种稳定载体，并且在20-99℃下将溶液混合通常至少10分钟、更通常20至30分钟，例如30分钟。pH可不调节，或可调节以维持pH为4至10，具体取决于所用载体的类型。溶液将包含山梨酸盐或者山梨酸盐和山梨酸的混合物，具体取决于pH。因此，调节pH可影响山梨酸盐与山梨酸的比例。低pH有利于较高量的山梨酸，而较高pH有利于存在较少山梨酸或不存在山梨酸。
可通过添加合适的酸或碱(诸如但不限于磷酸、柠檬酸或氢氧化钠)来调节pH。
潜在的稳定载体是有机酸、无机酸的氧化亲水性盐和甜菊醇糖苷，诸如磷酸二氢钾(KH2PO4)、柠檬酸盐诸如柠檬酸钾、酒石酸盐诸如酒石酸钠和六偏磷酸钠(SHMP)；多糖，包括麦芽糖糊精、阿拉伯树胶、果胶、卡拉胶、印度树胶、淀粉、藻酸盐、纤维素、改性淀粉、羧甲基纤维素(CMC)；甜菊醇糖苷，包括瑞鲍迪甙A、瑞鲍迪甙D或它们的组合。载体优选地不进行预处理，而是按原样使用。
稳定载体与山梨酸盐的比例在0.1:10至10:0.1、0.5:5至5:0.5、0.5:2至2:0.5的范围内。更通常地，该范围将为1:1。
然后对山梨酸盐-载体溶液进行喷雾干燥以产生精细的山梨酸盐固体分散体粉末。喷雾干燥可在200℃的干燥温度和10ml/min的流速下完成。粉末的粒度可为1至500微米、优选10至300微米。基于粉末的总重量计，山梨酸盐固体分散体粉末通常含有20至80重量％、或30至70重量％、或35至65重量％的山梨酸盐。山梨酸盐粉末是架藏稳定的。
在现有技术的饮料和糖浆中，山梨酸在饮料中的浓度通常小于500ppm，并且山梨酸在糖浆中的浓度通常小于1300ppm。在约20℃下、pH介于2.5和4之间的水溶液中(其为饮料和糖浆的典型制造条件)，在山梨酸盐浓度为约500ppm时山梨酸开始沉淀，除非采取阻止沉淀的步骤，并且在浓度为1300ppm时，沉淀倾向很明显。
相比之下，可以最高至2300ppm的量向水中添加根据本发明的各方面的山梨酸盐固体分散体粉末，具体取决于溶液是否旨在为糖浆(浓缩物)。山梨酸盐固体分散体粉末在轻微搅动下迅速溶解在水中。在本发明的各方面，汽水用糖浆的浓度为1000至2300ppm，更通常为1000至1500ppm。分散体在山梨酸盐为1000至2300ppm(w/v)时在各种汽水用糖浆(诸如，茶、柠檬水、水果宾治和碳酸化饮料，诸如可乐和柑橘风味糖浆)中是稳定的。
用山梨酸盐固体分散体粉末制备的汽水用糖浆在40℉下持续至少一个月不会发生山梨酸堆出(shock out)(沉淀)。然而，用未处理的山梨酸盐制备的汽水用糖浆在相同条件和相同水平下在7-20天内便堆出。
尽管不希望受任何理论束缚，但是通过山梨酸盐固体分散体粉末实现的溶解度和稳定性增强可归因于通过非共价键合(诸如氢键合)在山梨酸盐/山梨酸与稳定载体之间形成复合物。在汽水用糖浆中，与山梨酸盐/山梨酸相缔合的稳定载体可防止山梨酸结晶，从而导致物理稳定性增加。
山梨酸在固体分散体中的相对溶解度通过紫外-可见(UV-Vis)光度计确定。首先在室温下将山梨酸钾以0.25-0.5％(w/w)的浓度溶解在水中。通过添加pH为2.5-3.0的柠檬酸来酸化山梨酸盐溶液，从而导致山梨酸沉淀。通过离心去除沉淀的山梨酸，并将饱和溶液储存在40℉下。通过UV-vis在λmax＝263nm下测量山梨酸的相对浓度。结果表明，固体分散体中存在载体的山梨酸的吸收强度高于不存在载体的山梨酸盐对照的吸收强度(表2)。根据朗伯-比尔定律，山梨酸的浓度与吸收强度成正比(Abs(强度)＝K[山梨酸])。因此，吸收强度越高，山梨酸的溶解度越高。
载体类型影响山梨酸在糖浆和饮料中的溶解度和稳定性。含有六偏磷酸钠(SHMP)(具体地，作为载体)的山梨酸盐在低pH的缓冲溶液中表现出高稳定性。山梨酸盐/SHMP固体分散体在pH 2.5-3.0的缓冲溶液中是稳定的。与其它载体相比，在室温下酸化山梨酸盐溶液之后或在40℉下储存饱和溶液14天之后未观察到结晶。稳定性增加可归因于其粒度较小和负ζ电位较高。因为磷酸是pKa较低的强酸，所以山梨酸在水溶液中吸附的磷酸颗粒甚至在低pH下都携带高负电荷。也就是说，ζ电位和粒度似乎在稳定糖浆中的山梨酸中起重要作用。负ζ电位越高，山梨酸/SHMP的稳定性越高。根据DVLO理论的胶体稳定性，颗粒在溶液中的稳定性取决于其总势能(范德瓦尔斯引力、静电排斥力和位阻排斥力)。在总势能之中，很大程度上取决于ζ电位的静电排斥力控制颗粒稳定性。因此，负表面电荷高的山梨酸/SHMP颗粒通过糖浆和饮料中的静电排斥力来稳定。
因此，设想在基本上阻止山梨酸沉淀的同时，以宽范围的山梨酸浓度添加根据本发明的各方面的山梨酸盐。
如技术人员所认识到的，饮料或糖浆中的其它化合物也可能对山梨酸溶解度造成不利影响。例如，硬度可降低山梨酸的溶解度。实现商业保存条件所需的山梨酸浓度也涉及糖浆或饮料的其它条件。例如，碳酸化会降低实现给定保存性能所需的山梨酸的浓度。相比之下，降低pH可降低实现给定保存性能所需的山梨酸的浓度。在本文提供的指导下，技术人员将能够建立适当地保存糖浆或饮料的山梨酸浓度。
根据本发明的各方面，糖浆和饮料包含山梨酸作为防腐剂。其它防腐剂对于技术人员是已知的，并且可与山梨酸一起包括在其中。其它防腐剂包括例如螯合剂诸如EDTA(包括EDTA二钠、EDTA二钠钙和六偏磷酸钠(SHMP))和抗微生物剂诸如苯甲酸盐(尤其是碱金属苯甲酸盐)；月桂酰精氨酸酯；肉桂酸的盐；以及抗氧化剂，包括生育酚、BHA和BHT。根据本发明的实施方案，少量使用、并且最通常一点也不使用其它防腐剂。在本文提供的指导下，技术人员将能够选择适当的防腐剂。
本发明的饮料和糖浆实施方案的甜味剂包括含热量的碳水化合物甜味剂、天然的高效甜味剂、合成的高效甜味剂、其它甜味剂以及它们的组合。在本文提供的指导下，可选择合适的增甜体系(无论是单一化合物还是其组合)。
合适的含热量的碳水化合物甜味剂的示例包括蔗糖、果糖、葡萄糖、赤藓醇、麦芽糖醇、乳糖醇、山梨糖醇、甘露糖醇、木糖醇、D-塔格糖、海藻糖、半乳糖、鼠李糖、环糊精(例如，α-环糊精、β-环糊精和γ-环糊精)、核酮糖、苏阿糖、阿拉伯糖、木糖、来苏糖、阿洛糖、阿卓糖、甘露糖、艾杜糖、乳糖、麦芽糖、转化糖、异海藻糖、新海藻糖、帕拉金糖或异麦芽酮糖、赤藓糖、脱氧核糖、古洛糖、艾杜糖、塔罗糖、赤藓酮糖、木酮糖、阿洛酮糖、松二糖、纤维二糖、葡萄糖胺、甘露糖胺、海藻糖、葡萄醛酸、葡萄糖酸、葡糖酸-内酯、阿比可糖、半乳糖胺、低聚木糖(木三糖、木二糖等)、低聚龙胆糖(龙胆二糖、龙胆三糖、龙胆四糖等)、低聚半乳糖、山梨糖、低聚黑曲霉糖、低聚果糖(蔗果三糖、蔗果四糖等)、麦芽四醇、麦芽三醇、低聚麦芽糖(麦芽三糖、麦芽四糖、麦芽五糖、麦芽六糖、麦芽七糖等)、乳果糖、蜜二糖、蜜三糖、鼠李糖、核糖、异构化的液体糖(诸如，高果糖玉米/淀粉糖浆(例如HFCS55、HFCS42或HFCS90))、偶合糖、低聚大豆糖和葡萄糖浆。
适用于本文提供的实施方案中的其它甜味剂包括天然的高效甜味剂、合成的高效甜味剂和其它高效甜味剂。如本文所用，短语“天然的高效甜味剂”、“NHPS”、“NHPS组合物”和“天然的高效甜味剂组合物”是同义的。“NHPS”意指存在于自然界中的任何甜味剂，其可以单独地或组合地是未加工的、经提取的、经纯化的、经酶处理的或任何其它形式，并且在特征上具有高于蔗糖、果糖或葡萄糖的甜度效能，但仍具有较少热量。适用于本发明的实施方案的NHPS的非限制性示例包括瑞鲍迪甙A、瑞鲍迪甙B、瑞鲍迪甙C(杜尔可甙B)、瑞鲍迪甙D、瑞鲍迪甙E、瑞鲍迪甙F、杜尔可甙A、甜茶甙、甜菊糖甙、甜菊甙、罗汉果甙IV、罗汉果甙V、罗汉果甜味剂、赛门甙、莫那甜及其盐(莫那甜SS、RR、RS、SR)、仙茅甜蛋白、甘草酸及其盐、索马甜、莫内林、马宾灵、巴西甜、甜蜜素(hernandulcin)、叶甜素、菝葜苷、根皮苷、三叶苷(trilobtain)、白云参苷(baiyunoside)、欧亚水龙骨舌甘素(osladin)、多足蕨甙A、皮提罗甙A、皮提罗甙B、无患子倍半職甙、糙苏甙I、巴西甘草甜素I、相思子三職式A和青钱柳苷I。
NHPS还包括改性NHPS。改性NHPS包括已天然改变的NHPS。例如，改性NHPS包括但不限于，已经发酵、与酶接触或在NHPS上衍生或取代的NHPS。在一个实施方案中，至少一种改性NHPS可与至少一种NHPS组合使用。在另一个实施方案中，至少一种改性NHPS可在没有NHPS的情况下使用。因此，改性NHPS可替代NHPS或者可与NHPS组合用于本文中所述的任一个实施方案。然而，为简明起见，在本发明的实施方案的描述中，未将改性NHPS明确描述为未改性NHPS的替代物，但应当理解，在本文公开的任一个实施方案中，改性NHPS都可替代NHPS。
如本文所用，短语“合成甜味剂”是指并非存在于自然界中且为高效甜味剂的任何组合物。适用于本发明的实施方案的合成甜味剂(也称为人工甜味剂)的非限制性示例包括三氯蔗糖、安赛蜜钾(安赛蜜K或aceK)或其它盐、阿斯巴甜、阿力甜、糖精、新橙皮甙二氢查耳酮、甜精、纽甜、N-[3-(3-羟基-4-甲氧基苯基)丙基]-L-α-天冬氨酰]-L-苯丙氨酸1-甲酯、N-[3-(3-羟基-4-甲氧基苯基)-3-甲基丁基]-L-α-天冬氨酰]-L-苯丙氨酸1-甲酯、N-[3-(3-甲氧基-4-羟基苯基)丙基]-L-α-天冬氨酰]-L-苯丙氨酸1-甲酯，及其盐。
适用于本发明的实施方案的酸包括常用于饮料和饮料糖浆中的食品级酸。缓冲剂包括形成pH缓冲剂(即，提供趋于将pH维持在选定水平下的化合物组合)的食品级酸的盐。用于具体实施方案中的食品级酸包括但不限于磷酸、柠檬酸、抗坏血酸、己二酸、富马酸、乳酸、苹果酸、酒石酸、乙酸、草酸、单宁酸、绿原酸以及它们的组合。
常用于饮料和糖浆中的风味剂适用于本发明的实施方案的饮料和糖浆中。技术人员将认识到，一些风味剂会使饮料外观变混浊或增加浑浊度。因此，这种风味剂(通常可为乳剂)将不适用于澄清饮料。合适的风味剂包括常用于饮料和糖浆中的与饮料类型相容的风味剂。也就是说，澄清饮料通常不会用会使饮料变浑浊、引入混浊物或以其它方式使饮料对消费者的吸引力降低的风味剂来调味。但是，在技术人员已知这一条件的情况下，可视情况适当地使用已知的风味剂。
符合饮料类型的任何风味剂、风味化合物或风味剂体系均适用于本发明的实施方案中。此外，风味剂可为任何形式，诸如粉末、乳剂、微乳剂等。这些形式中的一些可在饮料中引起浑浊，因此不会用于澄清饮料中。典型的风味剂包括杏仁、杏仁甜酒、苹果、酸苹果、杏、蜜桃、香蕉、黑樱桃、樱桃、树莓、黑树莓、蓝莓、巧克力、肉桂、椰子、咖啡、可乐、越橘、奶油、爱尔兰奶油、水果宾治、姜、柑曼怡、葡萄、西柚、番石榴、红石榴汁、石榴、榛子、猕猴桃、柠檬、酸橙、柠檬/酸橙、橘子、柑橘、芒果、摩卡、橙子、木瓜、百香果、桃、梨、薄荷、留兰香、凤梨椰子、菠萝、草根啤酒、桦木啤酒、洋菝契、草莓、博伊森莓、茶、补剂、西瓜、甜瓜、野樱桃和香草。示例性风味剂是柠檬-酸橙、可乐、咖啡、茶、所有类型的水果风味剂以及它们的组合。
除聚山梨酸酯之外的表面活性剂也可存在于糖浆或饮料中，作为糖浆成分添加。技术人员将认识到，表面活性剂也可作为组成成分的一部分而引入糖浆或饮料中。通常适用于本发明的实施方案中的表面活性剂包括但不限于十二烷基苯磺酸钠、磺基琥珀酸二辛酯或磺基琥珀酸钠二辛酯、十二烷基硫酸钠、氯化十六烷基吡啶(十六烷基吡啶基氯)、溴化十六烷基三甲铵、胆酸钠、氨基甲酰、氯化胆碱、甘胆酸钠、牛磺脱氧胆酸钠、月桂酰精氨酸酯、硬脂酰乳酰酸钠、牛磺胆酸钠、卵磷脂、蔗糖油酸酯、蔗糖硬酸酯、蔗糖棕榈酸酯、蔗糖月桂酸酯以及其它表面活性剂。
技术人员将认识到，可以单独地或组合地添加各成分。另外，可制备干燥成分的溶液并用于向大量的水中方便地添加成分。
技术人员将认识到，如果在糖浆制造过程中使用高于环境温度的温度，则可在完成产品之后或通常在酸化之后且在添加挥发性物质之前降低糖浆的温度。通常，通过向大量的水中添加各成分来制备饮料糖浆。水的温度通常为至少50℉且通常小于200℉，常常介于50℉和160℉之间，并且通常介于50℉和130℉之间。
通常以使各成分之间的潜在不利相互作用或对成分的潜在不利影响达到最小的顺序向大量的水中添加各成分。例如，温敏性营养物可在接近制造过程结束的相对低温部分期间添加。类似地，风味剂和风味化合物通常在临糖浆完成之前添加，以使挥发性组分的潜在损失达到最小并且使任何形式的风味剂损失达到最小。通常，酸化是最后步骤之一，常在添加温敏性的挥发性风味剂物质之前进行。因此，风味剂或风味剂组分或其它挥发性物质和营养物通常在适当的时候和适当的温度下添加。在本文提供的指导下，技术人员可确定引入风味剂和其它挥发性物质的适当时间。
适当地使用这些顺序或其它成分添加顺序中的任一种，因为添加成分的顺序可在本文提供的指导下由技术人员确定。
包装所得糖浆，并且可将其储存。糖浆可基本上立即用于制造饮料，通常对所述饮料进行包装以便分配。也可将糖浆分配给装瓶工，装瓶工对通过添加水和可能的其它物质(如碳酸化物质)制备的饮料进行包装。通常，投为1+5。
本发明的具体方面是山梨酸盐分散体粉末在汽水饮料中的用途。糖浆通常被售给将糖浆与投水以及可能的其它成分(诸如，碳酸化物质)混合以便立即饮用的那些人。
本发明的其它实施方案涉及稳定保存的即饮型饮料的制造。这类饮料通过将等分量的糖浆与适量的稀释水进行混合来制备。通常，使用1体积糖浆与5体积水或其它流体的比例，也称为“1+5投”。
本发明的糖浆实施方案是用山梨酸保存的稳定饮料糖浆，所述糖浆的架藏期在室温下为至少三天或至少约一周。更通常地，本发明的糖浆实施方案的架藏期为至少四周、或至少七周、或至少二十周，并且甚至更通常为至少六个月。
本发明的饮料实施方案是用山梨酸保存的稳定饮料，所述饮料的架藏期在40℉和110℉之间的温度下为至少四周或至少十周。更通常地，本发明的饮料实施方案的架藏期为至少四周、或至少六周、或至少二十周，并且甚至更通常为至少六个月。
以下是本发明的各方面：
方面1：一种用于制备山梨酸盐粉末的方法，该方法包括将山梨酸盐溶解在水中，向山梨酸盐溶液中添加稳定载体，以及对载体-山梨酸盐溶液进行喷雾干燥以形成山梨酸盐粉末。
方面2：一种制备饮料糖浆的方法，该方法包括将水、山梨酸盐粉末和至少一种选自甜味剂和风味剂的成分混合，其中山梨酸盐-载体粉末通过以下过程制备：将山梨酸盐溶解在水中，向山梨酸盐溶液中添加稳定载体，以及对载体-山梨酸盐溶液进行喷雾干燥以形成山梨酸盐粉末。
方面3：一种饮料糖浆，包括将水、山梨酸盐粉末和至少一种选自甜味剂和风味剂的成分混合，其中山梨酸盐-载体粉末通过以下过程制备：将山梨酸盐溶解在水中，向山梨酸盐溶液中添加稳定载体，以及对载体-山梨酸盐溶液进行喷雾干燥以形成山梨酸盐粉末。该糖浆可包含1000至2300ppm或1000至1500ppm的山梨酸盐。
方面4：以上任何方面，其中山梨酸盐是山梨酸钾。
方面5：以上任何方面，其中载体选自有机酸和无机酸的氧化亲水性盐、多糖、甜菊醇糖苷或它们的组合，例如选自六偏磷酸钠(SHMP)、磷酸二氢钾、柠檬酸钾、酒石酸钠、麦芽糖糊精、阿拉伯树胶、果胶、卡拉胶、印度树胶、淀粉、藻酸盐、纤维素、改性淀粉、羧甲基纤维素(CMC)、瑞鲍迪甙A、瑞鲍迪甙D以及它们的组合。
方面6：以上任何方面，其中载体-山梨酸盐溶液的pH为4至10。
方面7：以上任何方面，还包括通过添加酸或碱，例如通过添加磷酸或氢氧化钠来调节pH。
方面8：以上任何方面，其中稳定载体与山梨酸盐的比例在0.1:10至10:0.1、0.5:5至5:0.5或1:1的范围内。
方面9：以上任何方面，其中基于粉末的总重量计，粉末包含20至80重量％、30至70重量％或35至65重量％的山梨酸盐。
以下实施例说明但并不限制本发明。
实施例1
向1000ml烧杯中添加15g山梨酸钾和500g水。在室温下混合15分钟之后，山梨酸钾完全溶解在水中。通过缓慢添加磷酸(50％)将山梨酸盐溶液的pH从9.2调节至6.0。然后，添加43g(35％)阿拉伯树胶溶液。将混合物混合20分钟。随后，对山梨酸盐/阿拉伯树胶溶液进行喷雾干燥，从而产生含有50％山梨酸钾的粉末。物质回收产率为85％。
实施例2
向500ml烧杯中添加25g山梨酸钾和300g水。在室温下混合15分钟之后，山梨酸钾完全溶解在水中，其中pH为8.85。然后，添加25g麦芽糖糊精(DE13-18％)粉末。将混合物混合20分钟。溶液pH从8.85降至8.3。随后，对山梨酸盐/麦芽糖糊精溶液进行喷雾干燥，从而产生含有50％山梨酸钾的粉末。物质回收产率为86％。
实施例3
向500ml烧杯中添加30g山梨酸钾和360g水。在室温下混合15分钟之后，山梨酸钾完全溶解在水中，其中pH为9.12。然后，添加30g柠檬酸钾粉末。将混合物混合20分钟。将溶液pH从9.2调节至8.45。随后，对山梨酸盐/柠檬酸盐溶液进行喷雾干燥，从而产生含有50％山梨酸钾的粉末。物质回收产率为80％。
实施例4
向500ml烧杯中添加15g单磷酸钾和200g水。在室温下混合15分钟之后，单磷酸钾完全溶解在水中，其中pH为4.3。通过缓慢添加23.22g氢氧化钠(3M)将单磷酸钾溶液的pH从4.3调节至6.9。然后，添加15g山梨酸钾。将混合物混合20分钟，其中pH为6.93。随后，对山梨酸盐/单磷酸钾溶液进行喷雾干燥，从而产生含有43.38％山梨酸钾的粉末。物质回收产率为87％。
实施例5
向500ml烧杯中添加20g单磷酸钾和200g水。在室温下混合15分钟之后，单磷酸钾完全溶解在水中，其中pH为4.38。通过缓慢添加20.47g氢氧化钠(3M)将单磷酸钾溶液的pH从4.48调节至6.76。然后，添加20g山梨酸钾。将混合物混合20分钟，其中pH为6.76。随后，对山梨酸盐/单磷酸钾溶液进行喷雾干燥，从而产生含有37％山梨酸钾的粉末。物质回收产率为85％。
实施例6
向500ml烧杯中添加20g山梨酸钾和360g水。在室温下混合15分钟之后，山梨酸钾完全溶解在水中，其中pH为8.92。将山梨酸盐溶液加热至45℃。通过添加0.45g磷酸(25％)将pH调节至7.02。然后，添加30g麦芽糖糊精(DE13-18％)粉末。将混合物混合20分钟。随后，对山梨酸盐/麦芽糖糊精溶液进行喷雾干燥，从而产生粉末。物质回收产率为87％。
实施例7
向500ml烧杯中添加28.3g六偏磷酸钠(SHMP)和150g水。在室温下混合15分钟之后，SHMP完全溶解在水中，其中pH为6.6。通过添加氢氧化钠(3M)将SHMP溶液的pH调节为6.8，然后添加5g山梨酸钾。将混合物混合20分钟。随后，对山梨酸盐/SHMP溶液进行喷雾干燥，从而产生粉末。物质回收产率为90％。
表1
表2
实施例8
向250ml烧杯中添加108g山梨酸钾和110g水。将混合物加热至45℃。在45℃下混合15分钟之后，山梨酸钾完全溶解在水中，其中pH为10.5。将混合物混合20分钟。随后，对山梨酸盐溶液进行喷雾干燥，从而产生粉末。物质回收产率为93％。
尽管已经相对于具体实施例(包括实现本发明的当前优选模式)描述了本发明，但本领域技术人员将认识到，存在上述系统和技术的许多变化和排列，这些都落入所附权利要求中所阐述的本发明的精神和范围之内。例如，在本发明的实施方案中制备其它澄清饮料，并且在本发明的实施方案中使用其它非水溶剂。
Claims (20)
1.一种用于制备山梨酸盐粉末的方法，所述方法包括将山梨酸盐溶解在水中，向所述山梨酸盐溶液中添加稳定载体，以及对所述载体-山梨酸盐溶液进行喷雾干燥以形成所述山梨酸盐粉末。
2.根据权利要求1所述的方法，其中所述山梨酸盐是山梨酸钾。
3.根据权利要求1所述的方法，其中所述载体选自有机酸和无机酸的氧化亲水性盐、多糖、甜菊醇糖苷或它们的组合。
4.根据权利要求1所述的方法，其中所述载体选自六偏磷酸钠(SHMP)、磷酸二氢钾、柠檬酸钾、酒石酸钠、麦芽糖糊精、阿拉伯树胶、果胶、卡拉胶、印度树胶、淀粉、藻酸盐、纤维素、改性淀粉、羧甲基纤维素(CMC)、瑞鲍迪甙A、瑞鲍迪甙D以及它们的组合。
5.根据权利要求1所述的方法，其中所述载体-山梨酸盐溶液的pH为4至11。
6.根据权利要求5所述的方法，所述方法还包括通过添加酸或碱来调节所述pH。
7.根据权利要求6所述的方法，所述方法还包括通过添加磷酸或氢氧化钠来调节所述pH。
8.根据权利要求1所述的方法，其中所述稳定载体与山梨酸盐的比例在0.1:10至10:0.1的范围内。
9.根据权利要求1所述的方法，其中所述稳定载体与山梨酸盐的比例在0.5:5至5:0.5的范围内。
10.根据权利要求1所述的方法，其中所述稳定载体与山梨酸盐的比例在1:1的范围内。
11.根据权利要求1所述的方法，其中基于所述粉末的总重量计，所述粉末包含20至80重量％的山梨酸盐。
12.一种制备饮料糖浆的方法，所述方法包括将水、山梨酸盐粉末和至少一种选自甜味剂和风味剂的成分混合，其中所述山梨酸盐-载体粉末通过以下过程制备：将山梨酸盐溶解在水中，向所述山梨酸盐溶液中添加稳定载体，以及对所述载体-山梨酸盐溶液进行喷雾干燥以形成所述山梨酸盐粉末。
13.根据权利要求12所述的方法，其中所述山梨酸盐是山梨酸钾。
14.根据权利要求12所述的方法，其中所述载体选自有机酸和无机酸的氧化亲水性盐、多糖、甜菊醇糖苷或它们的组合。
15.根据权利要求12所述的方法，其中所述载体选自六偏磷酸钠(SHMP)、磷酸二氢钾、柠檬酸钾、酒石酸钠、麦芽糖糊精、阿拉伯树胶、果胶、卡拉胶、印度树胶、淀粉、藻酸盐、纤维素、改性淀粉、羧甲基纤维素(CMC)、瑞鲍迪甙A、瑞鲍迪甙D以及它们的组合。
16.根据权利要求12所述的方法，其中所述稳定载体与山梨酸盐的比例在0.1:10至10:0.1的范围内。
17.根据权利要求12所述的方法，其中所述稳定载体与山梨酸盐的比例在0.5:5至5:0.5的范围内。
18.根据权利要求12所述的方法，其中基于所述粉末的总重量计，所述粉末包含20至80重量％的山梨酸盐。
19.一种饮料糖浆，所述饮料糖浆包括将水、山梨酸盐粉末和至少一种选自甜味剂和风味剂的成分混合，其中所述山梨酸盐-载体粉末通过以下过程制备：将山梨酸盐溶解在水中，向所述山梨酸盐溶液中添加稳定载体，以及对所述载体-山梨酸盐溶液进行喷雾干燥以形成所述山梨酸盐粉末。
20.根据权利要求19所述的饮料糖浆，所述饮料糖浆还包含1000至2300ppm的山梨酸盐。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/627,075 US11944111B2 (en) | 2015-02-20 | 2015-02-20 | Stabilizing sorbic acid in beverage syrup |
| US14/627,075 | 2015-02-20 | ||
| CN201680010884.6A CN107249350A (zh) | 2015-02-20 | 2016-02-18 | 稳定饮料糖浆中的山梨酸 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680010884.6A Division CN107249350A (zh) | 2015-02-20 | 2016-02-18 | 稳定饮料糖浆中的山梨酸 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113424908A true CN113424908A (zh) | 2021-09-24 |
Family
ID=56689500
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680010884.6A Pending CN107249350A (zh) | 2015-02-20 | 2016-02-18 | 稳定饮料糖浆中的山梨酸 |
| CN202110782224.2A Pending CN113424908A (zh) | 2015-02-20 | 2016-02-18 | 稳定饮料糖浆中的山梨酸 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680010884.6A Pending CN107249350A (zh) | 2015-02-20 | 2016-02-18 | 稳定饮料糖浆中的山梨酸 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11944111B2 (zh) |
| EP (1) | EP3258795B1 (zh) |
| JP (1) | JP6789956B2 (zh) |
| CN (2) | CN107249350A (zh) |
| AU (2) | AU2016220032B2 (zh) |
| BR (1) | BR112017017533A2 (zh) |
| CA (1) | CA2975388C (zh) |
| ES (1) | ES2773830T3 (zh) |
| MX (1) | MX2017010456A (zh) |
| PL (1) | PL3258795T3 (zh) |
| RU (1) | RU2716587C2 (zh) |
| WO (1) | WO2016134119A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020006674A2 (pt) | 2017-10-06 | 2020-10-06 | Cargill, Incorporated | composição de glicosídeo de esteviol prontamente dissolvível, e, composição seca de glicosídeo de esteviol prontamente dissolvível |
| BR112021019811A2 (pt) | 2019-04-06 | 2021-12-07 | Cargill Inc | Composição de glicosídeo de esteviol, bebida, métodos para reduzir um atributo sensorial indesejável de uma solução aquosa de glicosídeo de esteviol, para reduzir a persistência de doçura de um componente de glicosídeo de esteviol em uma composição comestível e para reduzir o amargor de um componente de glicosídeo de esteviol em uma composição comestível, e, soluções aquosa de glicosídeo de esteviol com reduzida persistência de doçura e aquosa de glicosídeo de esteviol com reduzido amargor |
| CN112876348A (zh) * | 2019-11-29 | 2021-06-01 | 南通醋酸化工股份有限公司 | 一种山梨酸钾水溶液合成方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172897A (en) * | 1977-03-17 | 1979-10-30 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Sorbic acid-containing powder or granules |
| WO2002043509A1 (en) * | 2000-11-30 | 2002-06-06 | Fmc Corporation | Beverage emulsion stabilizer |
| US20070054026A1 (en) * | 2005-09-06 | 2007-03-08 | Pepsico, Inc. | Method and apparatus for making beverages |
| US20140212564A1 (en) * | 2013-01-31 | 2014-07-31 | Pepsico, Inc. | Stabilizing Sorbic Acid In Syrup And Finished Beverage |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3021219A (en) | 1959-11-27 | 1962-02-13 | Corn Products Co | Process for preserving baked products |
| JPS584542B2 (ja) | 1975-06-03 | 1983-01-26 | チッソ株式会社 | ソルビンサンノケンダクエキモシクハペ−ストノ セイゾウホウ |
| CA1294821C (en) | 1985-12-26 | 1992-01-28 | Craig Joseph Bennett | Aqueous table syrup with reduced sugar content |
| US4784878A (en) * | 1987-04-06 | 1988-11-15 | Damrow Company, Inc. | Spray drying method and apparatus for concurrent particle coating |
| DE29521537U1 (de) | 1994-09-19 | 1998-04-30 | Hoechst Ag, 65929 Frankfurt | Flüssige und breiige Futtermittel aus Kartoffeln, Lebensmittelresten, Preßtreber, Bierhefe, Destillationsschlempe und ähnlichen Bestandteilen |
| MX9706538A (es) | 1995-02-28 | 1997-11-29 | Procter & Gamble | Preparacion de productos de bebida no carbonatada que tienen estabilidad microbiana superior. |
| JPH0947252A (ja) | 1995-08-04 | 1997-02-18 | Yoshihide Hagiwara | 水可溶性植物抽出物 |
| EP0866666B1 (en) * | 1995-12-15 | 2000-07-05 | The Procter & Gamble Company | Beverages having stable flavor/cloud emulsions in the presence of polyphosphate-containing preservative systems and low levels of xanthan gum |
| US5641532A (en) * | 1995-12-15 | 1997-06-24 | The Procter & Gamble Company | Beverages having stable flavor/cloud emulsions in the presence of polyphosphate-containing preservative systems by including gellan gum |
| US5714168A (en) | 1996-12-11 | 1998-02-03 | Basf Corporation | Method for increasing flowability of spray dried vitamin powders having low vitamin concentrations |
| US6036986A (en) * | 1997-10-28 | 2000-03-14 | Lipton, Division Of Conopco, Inc. | Cinnamic acid for use in tea containing beverages |
| JP4588166B2 (ja) | 1999-05-18 | 2010-11-24 | ダイセル化学工業株式会社 | ソルビン酸カリウム造粒物及びその製造法 |
| JP2001039922A (ja) | 1999-07-26 | 2001-02-13 | Lion Corp | ソルビン酸類の分解抑制方法及び液剤組成物 |
| NO20024880L (no) | 2002-03-19 | 2003-09-22 | Per Hamre | Sammensetning inneholdende fosfat |
| AU2003261414A1 (en) | 2002-09-10 | 2004-04-30 | Pepsico, Inc. | Use of surfactants to solubilize water-insoluble solids in beverages |
| AU2004221880A1 (en) | 2003-03-13 | 2004-09-30 | Mionix Corporation | Acidic composition and its uses |
| US20040219274A1 (en) | 2003-04-29 | 2004-11-04 | Cook Phillip Michael | Beverages containing water-soluble vitamin E |
| DE102004045622A1 (de) | 2004-09-17 | 2006-03-30 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Konservierungsmittel-Zusammensetzungen |
| ES2334849T3 (es) | 2006-03-07 | 2010-03-16 | DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG | Solubilizado de conservantes y metodo para su fabricacion. |
| US20070275140A1 (en) | 2006-05-26 | 2007-11-29 | Paula Safko | Beverage compositions comprising a preservative system |
| US20090074926A1 (en) | 2007-09-17 | 2009-03-19 | Purac Biochem B.V. | Preservation of acidic beverages |
| CN101243895B (zh) | 2008-02-29 | 2012-12-19 | 邹光友 | 一种红薯饮料的加工方法 |
| WO2010017050A1 (en) | 2008-08-07 | 2010-02-11 | Pepsico, Inc. | Extension of beverage shelf-stability by solute-ligand complexes |
| CN101810361A (zh) | 2010-01-05 | 2010-08-25 | 江南大学 | 一种微乳化食用保鲜剂产品及制备方法 |
| US8414942B2 (en) * | 2011-02-24 | 2013-04-09 | Pepsico, Inc. | Reduction of sorbic acid precipitation in beverages |
| WO2012154245A1 (en) * | 2011-02-24 | 2012-11-15 | Pepsico, Inc. | Reduction of sorbic acid precipitation |
| JP2013066458A (ja) | 2011-09-08 | 2013-04-18 | Taisho Pharmaceutical Co Ltd | 粉末飲料組成物 |
| GB201204377D0 (en) | 2012-03-13 | 2012-04-25 | Givaudan Sa | Composition |
| US9060537B2 (en) * | 2012-03-26 | 2015-06-23 | Pepsico, Inc. | Method for enhancing rebaudioside D solubility in water |
| CN105338828A (zh) | 2013-06-26 | 2016-02-17 | 三菱化学食品株式会社 | 粉末组合物、该粉末组合物的制造方法和饮料 |
| US10905146B2 (en) * | 2013-07-12 | 2021-02-02 | The Coca-Cola Company | Compositions for improving rebaudioside M solubility |
-
2015
- 2015-02-20 US US14/627,075 patent/US11944111B2/en active Active
-
2016
- 2016-02-18 ES ES16753041T patent/ES2773830T3/es active Active
- 2016-02-18 PL PL16753041T patent/PL3258795T3/pl unknown
- 2016-02-18 WO PCT/US2016/018424 patent/WO2016134119A1/en active Application Filing
- 2016-02-18 AU AU2016220032A patent/AU2016220032B2/en active Active
- 2016-02-18 JP JP2017543738A patent/JP6789956B2/ja active Active
- 2016-02-18 RU RU2017131911A patent/RU2716587C2/ru active
- 2016-02-18 CA CA2975388A patent/CA2975388C/en active Active
- 2016-02-18 CN CN201680010884.6A patent/CN107249350A/zh active Pending
- 2016-02-18 MX MX2017010456A patent/MX2017010456A/es unknown
- 2016-02-18 EP EP16753041.9A patent/EP3258795B1/en active Active
- 2016-02-18 BR BR112017017533-9A patent/BR112017017533A2/pt not_active Application Discontinuation
- 2016-02-18 CN CN202110782224.2A patent/CN113424908A/zh active Pending
-
2020
- 2020-08-19 AU AU2020220115A patent/AU2020220115B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172897A (en) * | 1977-03-17 | 1979-10-30 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Sorbic acid-containing powder or granules |
| WO2002043509A1 (en) * | 2000-11-30 | 2002-06-06 | Fmc Corporation | Beverage emulsion stabilizer |
| US20070054026A1 (en) * | 2005-09-06 | 2007-03-08 | Pepsico, Inc. | Method and apparatus for making beverages |
| US20140212564A1 (en) * | 2013-01-31 | 2014-07-31 | Pepsico, Inc. | Stabilizing Sorbic Acid In Syrup And Finished Beverage |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016220032A1 (en) | 2017-08-17 |
| WO2016134119A1 (en) | 2016-08-25 |
| EP3258795B1 (en) | 2019-12-25 |
| US11944111B2 (en) | 2024-04-02 |
| CA2975388C (en) | 2023-04-18 |
| MX2017010456A (es) | 2018-01-23 |
| AU2016220032B2 (en) | 2020-05-28 |
| PL3258795T3 (pl) | 2020-07-27 |
| EP3258795A4 (en) | 2018-10-24 |
| EP3258795A1 (en) | 2017-12-27 |
| CN107249350A (zh) | 2017-10-13 |
| RU2017131911A3 (zh) | 2019-04-29 |
| JP2018507206A (ja) | 2018-03-15 |
| RU2017131911A (ru) | 2019-03-20 |
| AU2020220115B2 (en) | 2022-06-30 |
| BR112017017533A2 (pt) | 2018-04-17 |
| RU2716587C2 (ru) | 2020-03-12 |
| ES2773830T3 (es) | 2020-07-15 |
| CA2975388A1 (en) | 2016-08-25 |
| JP6789956B2 (ja) | 2020-11-25 |
| US20160242452A1 (en) | 2016-08-25 |
| AU2020220115A1 (en) | 2020-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2741621B1 (en) | Shelf stable, low water liquid beverage concentrates | |
| AU2020220115B2 (en) | Stabilizing sorbic acid in beverage syrup | |
| US20200178571A1 (en) | Beverage Concentrates With Increased Viscosity And Shelf Life And Methods Of Making The Same | |
| EP2854568B1 (en) | Natural clouding system for beverage applications | |
| JP2016537968A (ja) | ゼロまたは低カロリーのフローズン飲料におけるｄ−プシコース | |
| WO2013134627A1 (en) | Beverage concentrates with increased viscosity and shelf life and methods of making the same | |
| US10327460B2 (en) | Stable low acid beverage concentrate | |
| JP2019535305A (ja) | 低カロリー及びノンカロリー飲料用の口当たりブレンド | |
| JP6146593B2 (ja) | ソルビン酸沈殿物の減少 | |
| US20210084942A1 (en) | Quillaja-stabilized liquid beverage concentrates and methods of making same | |
| US8414942B2 (en) | Reduction of sorbic acid precipitation in beverages | |
| US8697163B2 (en) | Reduction of sorbic acid precipitation by forming microemulsion | |
| US8563062B2 (en) | Reduction of sorbic acid precipitation by volume control | |
| US8691309B2 (en) | Reduction of sorbic acid precipitation | |
| US20120219679A1 (en) | Reduction of sorbic acid precipitation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |