CN113423821A - 分离和扩增细胞的方法 - Google Patents

分离和扩增细胞的方法 Download PDF

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Publication number
CN113423821A
CN113423821A CN201980088258.2A CN201980088258A CN113423821A CN 113423821 A CN113423821 A CN 113423821A CN 201980088258 A CN201980088258 A CN 201980088258A CN 113423821 A CN113423821 A CN 113423821A
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cells
hematopoietic tissue
tissue sample
population
cell
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Chinese (zh)
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S·班达里
S·佛罗伦斯
A·赫顿
L·马蒂亚斯
O·努斯鲍默
K·索德斯特罗姆
M·乌登
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Gamma Delta Therapy Co ltd
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Gamma Delta Therapy Co ltd
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/14—Blood; Artificial blood
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2315—Interleukin-15 (IL-15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
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    • C12N2513/00—3D culture

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201980088258.2A 2018-11-08 2019-11-08 分离和扩增细胞的方法 Pending CN113423821A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1818243.6 2018-11-08
GBGB1818243.6A GB201818243D0 (en) 2018-11-08 2018-11-08 Methods for isolating and expanding cells
PCT/GB2019/053166 WO2020095059A1 (en) 2018-11-08 2019-11-08 Methods for isolating and expanding cells

Publications (1)

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CN113423821A true CN113423821A (zh) 2021-09-21

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CN201980088258.2A Pending CN113423821A (zh) 2018-11-08 2019-11-08 分离和扩增细胞的方法

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Country Link
US (1) US12460180B2 (https=)
EP (1) EP3877510A1 (https=)
JP (2) JP7665513B2 (https=)
KR (1) KR20210111747A (https=)
CN (1) CN113423821A (https=)
AU (1) AU2019374489B2 (https=)
BR (1) BR112021008166A2 (https=)
CA (1) CA3117913A1 (https=)
EA (1) EA202190864A1 (https=)
GB (1) GB201818243D0 (https=)
IL (1) IL282901A (https=)
MX (1) MX2021005480A (https=)
PH (1) PH12021551038A1 (https=)
WO (1) WO2020095059A1 (https=)

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GB201818243D0 (en) 2018-11-08 2018-12-26 Gammadelta Therapeutics Ltd Methods for isolating and expanding cells
JP2022545196A (ja) 2019-08-16 2022-10-26 ガンマデルタ セラピューティクス リミテッド 抗ｔｃｒデルタ可変１抗体の治療的使用
JP7764364B2 (ja) 2019-08-16 2025-11-05 ガンマデルタ セラピューティクス リミティッド エクスビボγδ Ｔ細胞集団
GB202002581D0 (en) 2020-02-24 2020-04-08 Gammadelta Therapeutics Ltd Novel antibodies
PL4269444T3 (pl) 2020-08-14 2025-01-13 GammaDelta Therapeutics Limited Wieloswoiste przeciwciała anty-tcr zmienne delta 1
AU2022224391A1 (en) 2021-02-17 2023-08-24 Gammadelta Therapeutics Ltd Anti-tcr delta variable 1 antibodies
GB202105113D0 (en) 2021-04-09 2021-05-26 Gammadelta Therapeutics Ltd Novel method
CA3228168A1 (en) 2021-08-03 2023-02-09 Gammadelta Therapeutics Ltd Engineering of gamma delta t cells and compositions thereof
EP4504247A1 (en) 2022-04-04 2025-02-12 Gammadelta Therapeutics Ltd Novel gene armoring
GB202204926D0 (en) 2022-04-04 2022-05-18 Gammadelta Therapeutics Ltd Method for expanding gammadelta T cells
CN121532496A (zh) * 2023-07-20 2026-02-13 武田药品工业株式会社 用于制备γδT细胞的无网格方法

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EP1777294A1 (en) 2005-10-20 2007-04-25 Institut National De La Sante Et De La Recherche Medicale (Inserm) IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins
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US20220010276A1 (en) 2022-01-13
WO2020095059A1 (en) 2020-05-14
MX2021005480A (es) 2021-11-04
CA3117913A1 (en) 2020-05-14
BR112021008166A2 (pt) 2021-08-03
US12460180B2 (en) 2025-11-04
EP3877510A1 (en) 2021-09-15
EA202190864A1 (ru) 2021-09-14
IL282901A (en) 2021-06-30
KR20210111747A (ko) 2021-09-13
JP2025106453A (ja) 2025-07-15
PH12021551038A1 (en) 2022-01-03
AU2019374489B2 (en) 2026-04-02
JP2022506841A (ja) 2022-01-17
JP7665513B2 (ja) 2025-04-21
GB201818243D0 (en) 2018-12-26
AU2019374489A1 (en) 2021-05-27

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