CN113398047A - Hydrogen peroxide-containing hand disinfectant and preparation method thereof - Google Patents

Hydrogen peroxide-containing hand disinfectant and preparation method thereof Download PDF

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Publication number
CN113398047A
CN113398047A CN202110749092.3A CN202110749092A CN113398047A CN 113398047 A CN113398047 A CN 113398047A CN 202110749092 A CN202110749092 A CN 202110749092A CN 113398047 A CN113398047 A CN 113398047A
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Prior art keywords
hydrogen peroxide
hand sanitizer
containing hand
essence
hand
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CN202110749092.3A
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Chinese (zh)
Inventor
魏希庆
庞元金
韩堃
李鹏章
刘明明
勾长磊
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Shandong Xinhua Saroya Biotechnology Co ltd
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Shandong Xinhua Saroya Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/046Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention belongs to the technical field of hand disinfectants, and particularly relates to a hydrogen peroxide-containing hand disinfectant and a preparation method thereof, wherein the hand disinfectant is prepared from the following raw materials in percentage by weight: 50-90% of ethanol, 0.01-1% of hydrogen peroxide, 0.1-1% of natural skin care substances, 0.5-2% of moisturizing substances, 0.1-1% of auxiliary agents, 0.01-0.5% of essence and the balance of water. The hand disinfectant disclosed by the invention is simple and convenient to operate, safe and environment-friendly in raw materials, outstanding in sterilization effect, fresh in hand feeling, fresh in smell and good in skin care effect; the invention also provides a simple and feasible preparation method.

Description

Hydrogen peroxide-containing hand disinfectant and preparation method thereof
Technical Field
The invention belongs to the technical field of hand disinfectants, and particularly relates to a hydrogen peroxide-containing hand disinfectant and a preparation method thereof.
Background
At present, the main sterilization component of the hand disinfectant is single-component alcohol, or other components such as chlorhexidine are added, and the single alcohol and the addition are not sensitive to non-enveloped viruses. Hand disinfectants are often used to dry, chap and irritate the skin of the hands of medical personnel.
Based on the above situation, the hand sanitizer which has a good sterilization effect and can moisturize and protect the skin has a good market prospect.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: the defects of the prior art are overcome, and the hydrogen peroxide-containing hand disinfectant is provided, and has the advantages of environment-friendly and easily-obtained raw materials, good sterilization effect, good skin care effect and simple and convenient operation; the invention also provides a simple and feasible preparation method.
The hydrogen peroxide-containing hand disinfectant disclosed by the invention comprises the following raw materials in percentage by weight:
Figure RE-GDA0003187841210000011
preferably, the hydrogen peroxide-containing hand sanitizer consists of the following raw materials in percentage by weight:
Figure RE-GDA0003187841210000012
preferably, the hydrogen peroxide-containing hand sanitizer consists of the following raw materials in percentage by weight:
Figure RE-GDA0003187841210000021
preferably, the hydrogen peroxide-containing hand sanitizer consists of the following raw materials in percentage by weight:
Figure RE-GDA0003187841210000022
preferably, the ethanol is one of food-grade ethanol or medical-grade ethanol.
Preferably, the hydrogen peroxide is one of food grade hydrogen peroxide or medical grade hydrogen peroxide.
Preferably, the natural skin care substance is aloe extract, and is of daily chemical grade or above.
Preferably, the moisturizing substance is glycerin.
Preferably, the adjuvant is isopropyl myristate.
Preferably, the essence is one of cherry essence, aloe essence or apple essence.
Preferably, the water is purified water.
The preparation method of the hydrogen peroxide-containing hand disinfectant comprises the steps of adding ethanol into a container, starting stirring, wherein the rotation speed is preferably 40-200rpm/min, sequentially adding the natural skin care substances and the moisturizing substances, adding the auxiliary agents, the essence and the hydrogen peroxide after dissolving, stirring for 5-25min, adding purified water, and stirring for 5-25min to obtain the hydrogen peroxide-containing hand disinfectant.
The disinfectant is a spray type disinfectant, is uniformly sprayed, and has the effects of moistening and protecting the skin while disinfecting hands; by means of the excellent sterilizing effect of the hydrogen peroxide, the non-enveloped virus can be effectively killed, and the natural skin care substances, the moisturizing substances and the auxiliary agents are mutually matched to moisten and care the skin.
The hand sanitizer can be used for daily hand sanitization, sanitary hand sanitization, and surgical hand sanitization.
The application method of the hand disinfectant comprises the following steps: the hand sanitizer is used according to the standard method of surgical hand sanitization and sanitary hand sanitization, can effectively kill natural bacteria of hands (and kill non-enveloped viruses), has good skin care effect, moistens and protects the skin while the hands are kept sanitary, reduces the infection rate of hospitals, and improves the working efficiency of medical care personnel.
Compared with the prior art, the invention has the following beneficial effects:
(1) the hand sanitizer has the advantages of environment-friendly and non-irritant raw materials.
(2) The hand disinfectant is quick to dry and refreshing in hand feeling.
(3) The hand disinfectant has good moistening and skin-care effects.
(4) The hand disinfectant has fresh smell.
(5) The hand disinfectant has excellent sterilizing capability, can kill microorganisms in a broad spectrum, and can effectively reduce the incidence rate of hospital infection events.
(6) The invention also provides a simple and easy preparation method of the hand sanitizer.
Detailed Description
The present invention is further illustrated by the following examples, which are not intended to limit the practice of the invention.
Example 1
The hand sanitizer comprises the following components in percentage by mass:
Figure RE-GDA0003187841210000031
wherein: the ethanol is edible special grade ethanol, the hydrogen peroxide is food grade hydrogen peroxide, the natural skin care substance is aloe extract (daily chemical grade), the moisturizing substance is glycerin, the auxiliary agent is isopropyl myristate, and the essence is cherry blossom essence.
Adding the ethanol into a container, stirring at 50rpm/min, sequentially adding the natural skin care substances and the moisturizing substances, dissolving, adding the adjuvants, essence and hydrogen peroxide, stirring for 25min, adding purified water, and stirring for 25 min. The hand disinfectant is prepared.
Example 2
The hand sanitizer comprises the following components in percentage by mass:
Figure RE-GDA0003187841210000032
Figure RE-GDA0003187841210000041
wherein: the ethanol is edible special grade ethanol, the hydrogen peroxide is food grade hydrogen peroxide, the natural skin care substance is aloe extract (daily chemical grade), the moisturizing substance is glycerin, the auxiliary agent is isopropyl myristate, and the essence is cherry blossom essence.
Adding the ethanol into a container, stirring at 100rpm/min, sequentially adding the natural skin care substances and the moisturizing substances, dissolving, adding the adjuvants, essence and hydrogen peroxide, stirring for 12min, adding purified water, and stirring for 15 min. The hand disinfectant is prepared.
Example 3
The hand sanitizer comprises the following components in percentage by mass:
Figure RE-GDA0003187841210000042
wherein: the ethanol is edible special grade ethanol, the hydrogen peroxide is food grade hydrogen peroxide, the natural skin care substance is aloe extract (daily chemical grade), the moisturizing substance is glycerin, the auxiliary agent is isopropyl myristate, and the essence is cherry blossom essence.
Adding the ethanol into a container, stirring at a rotation speed of 200pm/min, sequentially adding the natural skin care substance and the moisturizing substance, dissolving, adding the auxiliary agent, essence and hydrogen peroxide, stirring for 8min, adding purified water, and stirring for 7 min. The hand disinfectant is prepared.
Of course, the foregoing is only a preferred embodiment of the invention and should not be taken as limiting the scope of the embodiments of the invention. The present invention is not limited to the above examples, and equivalent changes and modifications made by those skilled in the art within the spirit and scope of the present invention should be construed as being included in the scope of the present invention.

Claims (10)

1. A hydrogen peroxide-containing hand sanitizer characterized by: the composite material consists of the following raw materials in percentage by weight:
Figure FDA0003143796920000011
the balance being water.
2. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the composite material consists of the following raw materials in percentage by weight:
Figure FDA0003143796920000012
the balance being water.
3. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the composite material consists of the following raw materials in percentage by weight:
Figure FDA0003143796920000013
the balance being water.
4. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the composite material consists of the following raw materials in percentage by weight:
Figure FDA0003143796920000014
Figure FDA0003143796920000021
the balance being water.
5. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the ethanol is one of food-grade ethanol or medical-grade ethanol.
6. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the hydrogen peroxide is one of food-grade hydrogen peroxide or medical-grade hydrogen peroxide.
7. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the natural skin care substance is aloe extract, and is daily chemical grade or above.
8. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the moisturizing substance is glycerin; the auxiliary agent is isopropyl myristate.
9. The hydrogen peroxide-containing hand sanitizer according to claim 1, wherein: the essence is one of cherry blossom essence, aloe essence or apple essence.
10. A method of preparing a hydrogen peroxide-containing hand sanitizer according to any of claims 1-9, wherein: adding ethanol into a container, stirring, sequentially adding natural skin care substances and moisturizing substances, dissolving, adding adjuvants, essence and hydrogen peroxide, stirring for 5-25min, adding water, and stirring for 5-25min to obtain the hand disinfectant.
CN202110749092.3A 2021-07-01 2021-07-01 Hydrogen peroxide-containing hand disinfectant and preparation method thereof Pending CN113398047A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102696674A (en) * 2012-06-05 2012-10-03 上海利康消毒高科技有限公司 Low-concentration hydrogen peroxide disinfectant and preparation method thereof
CN107318886A (en) * 2017-06-30 2017-11-07 上海哈勃化学技术有限公司 A kind of composite disinfectant product and its preparation
CN108721126A (en) * 2018-08-07 2018-11-02 夏战利 A kind of anti-bacterial hand lotion
CN111388339A (en) * 2020-03-27 2020-07-10 陈乐� Novel quick washing-free disinfectant
CN111700822A (en) * 2020-07-23 2020-09-25 广州泰晟生物科技股份有限公司 Skin disinfectant and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102696674A (en) * 2012-06-05 2012-10-03 上海利康消毒高科技有限公司 Low-concentration hydrogen peroxide disinfectant and preparation method thereof
CN107318886A (en) * 2017-06-30 2017-11-07 上海哈勃化学技术有限公司 A kind of composite disinfectant product and its preparation
CN108721126A (en) * 2018-08-07 2018-11-02 夏战利 A kind of anti-bacterial hand lotion
CN111388339A (en) * 2020-03-27 2020-07-10 陈乐� Novel quick washing-free disinfectant
CN111700822A (en) * 2020-07-23 2020-09-25 广州泰晟生物科技股份有限公司 Skin disinfectant and preparation method thereof

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Application publication date: 20210917