CN113244209A - 柠檬酸铁在治疗慢性肾脏疾病患者中的应用 - Google Patents

柠檬酸铁在治疗慢性肾脏疾病患者中的应用 Download PDF

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Publication number
CN113244209A
CN113244209A CN202110644193.4A CN202110644193A CN113244209A CN 113244209 A CN113244209 A CN 113244209A CN 202110644193 A CN202110644193 A CN 202110644193A CN 113244209 A CN113244209 A CN 113244209A
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CN
China
Prior art keywords
ferric citrate
iron
patient
increase
mean
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110644193.4A
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English (en)
Chinese (zh)
Inventor
恩里克·普拉多苏
罗恩·本图尔
詹姆斯·F·奥利维耶罗三世
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keryx Biopharmaceuticals Inc
Original Assignee
Keryx Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keryx Biopharmaceuticals Inc filed Critical Keryx Biopharmaceuticals Inc
Publication of CN113244209A publication Critical patent/CN113244209A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202110644193.4A 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用 Pending CN113244209A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261662565P 2012-06-21 2012-06-21
US61/662,565 2012-06-21
US201361757229P 2013-01-28 2013-01-28
US61/757,229 2013-01-28
US201361800618P 2013-03-15 2013-03-15
US201361801050P 2013-03-15 2013-03-15
US61/801,050 2013-03-15
US61/800,618 2013-03-15
CN201380044271.0A CN104884055A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380044271.0A Division CN104884055A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Publications (1)

Publication Number Publication Date
CN113244209A true CN113244209A (zh) 2021-08-13

Family

ID=49769729

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202110644193.4A Pending CN113244209A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用
CN201380044271.0A Pending CN104884055A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201380044271.0A Pending CN104884055A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Country Status (19)

Country Link
US (3) US20130345303A1 (https=)
EP (3) EP2863906B1 (https=)
JP (4) JP2015535209A (https=)
KR (2) KR20200103855A (https=)
CN (2) CN113244209A (https=)
AU (2) AU2013278000A1 (https=)
BR (1) BR112014032049A2 (https=)
CA (1) CA2876982A1 (https=)
DK (1) DK3730136T3 (https=)
EA (1) EA201590062A1 (https=)
ES (2) ES2796254T3 (https=)
FR (1) FR25C1043I1 (https=)
HK (1) HK1214503A1 (https=)
IL (1) IL236356A0 (https=)
MX (1) MX2014015615A (https=)
NO (1) NO2025048I1 (https=)
PL (1) PL3730136T3 (https=)
SG (2) SG11201408521WA (https=)
WO (1) WO2013192565A2 (https=)

Cited By (1)

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CN115024495A (zh) * 2022-06-27 2022-09-09 北京金康普食品科技有限公司 改善肾病患者钙磷代谢的营养组合物及其应用

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WO2011011541A1 (en) 2009-07-21 2011-01-27 Henry Trong Le Ferric citrate dosage forms
TWI653043B (zh) * 2012-12-20 2019-03-11 瑞士商伊蘭科動物健康公司 新用途
EP3003327B1 (en) 2013-06-05 2017-08-09 Tricida Inc. Proton-binding polymers for oral administration
EP2856941B1 (en) * 2013-10-01 2020-11-25 Fresenius Medical Care Deutschland GmbH Method and apparatuses for determining a patient's daily loss of iron
EP3747432A1 (en) * 2013-11-04 2020-12-09 Keryx Biopharmaceuticals, Inc. Ferric citrate for reducing cardiac failure in chronic kidney disease patients
WO2015110968A1 (en) * 2014-01-23 2015-07-30 Lupin Limited Pharmaceutical grade ferric citrate and method for its production
EP3157516A4 (en) 2014-06-22 2017-12-13 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
RS61409B1 (sr) 2014-12-10 2021-03-31 Tricida Inc Polimeri koji vezuju protone za oralnu primenu opis
TW202302083A (zh) * 2015-03-04 2023-01-16 美商凱克斯生物製藥公司 檸檬酸鐵用於治療缺鐵性貧血之用途
CN104688706B (zh) * 2015-04-01 2017-07-14 成都欣捷高新技术开发有限公司 一种高载药量、快速溶出的枸橼酸铁组合物及其制备方法
WO2016162794A1 (en) * 2015-04-08 2016-10-13 Leiutis Pharmaceuticals Pvt Ltd Pharmaceutical compositions of ferric citrate
WO2016162888A1 (en) * 2015-04-09 2016-10-13 Actavis Group Ptc Ehf. Process for preparing pharmaceutical grade ferric citrate
CN109414453B (zh) 2016-05-06 2023-02-17 特里赛达公司 用于治疗酸碱失衡的组合物
WO2019059172A1 (ja) 2017-09-19 2019-03-28 日本たばこ産業株式会社 過多月経患者及び／又は過多月経を伴う婦人科疾患を有する患者における鉄欠乏性貧血の予防及び／又は治療におけるクエン酸第二鉄の使用
CA3080651A1 (en) 2017-11-03 2019-05-09 Tricida, Inc. Compositions for and method of treating acid-base disorders
WO2019236639A1 (en) * 2018-06-04 2019-12-12 Tricida, Inc. Method of treating acid-base disorders
MX2021004640A (es) 2018-10-29 2021-05-28 Pharmacosmos Holding As Tratamiento de la deficiencia de hierro con carboximaltosa ferrica.
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
EP4347022A1 (en) 2021-05-27 2024-04-10 Keryx Biopharmaceuticals, Inc. Pediatric formulations of ferric citrate
WO2025181559A1 (en) * 2024-02-29 2025-09-04 Sloiron, Inc. Methods for determining the amount of encapsulated and free iron in a sample

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CN1600302A (zh) * 2003-09-22 2005-03-30 宝龄富锦生技股份有限公司 含有柠檬酸铁的医药组合物以及药用级柠檬酸铁及其制法和含有药用级柠檬酸铁的膳食营养品
CN1751056A (zh) * 2003-02-19 2006-03-22 环亚有限公司 铁有机化合物、其应用及其制备方法

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CN1230118A (zh) * 1996-07-19 1999-09-29 日研化学株式会社 高磷血症治疗剂
US5753706A (en) * 1996-12-16 1998-05-19 Hsu; Chen Hsing Methods for treating renal failure
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
US20060134227A1 (en) * 2004-12-22 2006-06-22 Bortz Jonathan D Compositions including iron
CA2619591C (en) 2005-08-18 2020-03-24 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same
PT1973549T (pt) * 2006-01-06 2016-10-25 Luitpold Pharm Inc Métodos e composições para administração de ferro
JP2009525277A (ja) * 2006-01-30 2009-07-09 グロボアジア エルエルシー 軟組織石灰化の回復、予防、遅延または安定化方法
WO2011011541A1 (en) 2009-07-21 2011-01-27 Henry Trong Le Ferric citrate dosage forms

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1751056A (zh) * 2003-02-19 2006-03-22 环亚有限公司 铁有机化合物、其应用及其制备方法
CN1600302A (zh) * 2003-09-22 2005-03-30 宝龄富锦生技股份有限公司 含有柠檬酸铁的医药组合物以及药用级柠檬酸铁及其制法和含有药用级柠檬酸铁的膳食营养品

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115024495A (zh) * 2022-06-27 2022-09-09 北京金康普食品科技有限公司 改善肾病患者钙磷代谢的营养组合物及其应用
CN115024495B (zh) * 2022-06-27 2024-03-22 北京金康普食品科技有限公司 改善肾病患者钙磷代谢的营养组合物及其应用

Also Published As

Publication number Publication date
ES2970050T3 (es) 2024-05-24
EP2863906B1 (en) 2020-03-18
WO2013192565A3 (en) 2015-10-15
CN104884055A (zh) 2015-09-02
EP3730136A1 (en) 2020-10-28
JP2022070945A (ja) 2022-05-13
US20140234416A1 (en) 2014-08-21
CA2876982A1 (en) 2013-12-27
AU2018203205B2 (en) 2020-03-12
US20150079168A1 (en) 2015-03-19
NO2025048I1 (no) 2025-11-06
JP2018138562A (ja) 2018-09-06
ES2796254T3 (es) 2020-11-26
KR102150135B1 (ko) 2020-08-31
WO2013192565A2 (en) 2013-12-27
BR112014032049A2 (pt) 2017-07-25
AU2018203205A1 (en) 2018-05-31
US20130345303A1 (en) 2013-12-26
EP4335436A2 (en) 2024-03-13
IL236356A0 (en) 2015-02-26
FR25C1043I1 (fr) 2026-01-02
EP3730136B1 (en) 2023-12-27
DK3730136T3 (da) 2024-01-22
PL3730136T3 (pl) 2024-03-25
JP2015535209A (ja) 2015-12-10
HK1214503A1 (zh) 2016-07-29
SG11201408521WA (en) 2015-01-29
EP2863906A2 (en) 2015-04-29
SG10201805177PA (en) 2018-07-30
HK1210013A1 (en) 2016-04-15
KR20200103855A (ko) 2020-09-02
AU2013278000A1 (en) 2015-01-22
MX2014015615A (es) 2015-03-20
EP4335436A3 (en) 2024-05-15
KR20150036131A (ko) 2015-04-07
EA201590062A1 (ru) 2016-02-29
JP2020100638A (ja) 2020-07-02

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Application publication date: 20210813

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