CN113197978A - A composition preparation with effects of invigorating primordial qi, warming, nourishing yin and promoting health, and its preparation method - Google Patents

A composition preparation with effects of invigorating primordial qi, warming, nourishing yin and promoting health, and its preparation method Download PDF

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CN113197978A
CN113197978A CN202110440274.2A CN202110440274A CN113197978A CN 113197978 A CN113197978 A CN 113197978A CN 202110440274 A CN202110440274 A CN 202110440274A CN 113197978 A CN113197978 A CN 113197978A
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weight
warming
preparation
carbon dioxide
nourishing yin
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刘晓枫
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Abstract

The invention discloses a combined preparation with the effects of benefiting vitality, warming, nourishing yin and preserving health and a preparation method thereof, and the combined preparation comprises the following raw materials, by weight, 10-25% of nostoc sphaeroides, 1-4% of adenophora giraldii, 2-5% of lycoris radiata, 8-16% of prepared rehmannia root, 1-3% of deerhorn glue, 2-4% of cinnamon, 0.5-1% of angelica sinensis, 0.2-0.8% of angelica dahurica, 0.4-0.6% of radix paeoniae alba, 0.3-0.7% of bighead atractylodes rhizome, 2-3% of honey-fried licorice root, 4-9% of rock candy, 30-65% of water, 2-6% of yellow wine and 3-6% of an additive, and is suitable for the taste of the public, fragrant in air temperature; the Chinese medicinal composition has the effects of warming and moistening, tonifying primordial essence and yin, balancing sexual and taste, tonifying qi, preserving health, nourishing liver and kidney, fully regulating functions of the liver and the kidney and achieving the purpose of improving the life quality of a patient with fatigue.

Description

A composition preparation with effects of invigorating primordial qi, warming, nourishing yin and promoting health, and its preparation method
Technical Field
The invention relates to the technical field of nutritional agents, in particular to a combined preparation with the effects of tonifying vitality, warming, nourishing yin and preserving health and a preparation method thereof.
Background
According to the results of modern medical research, fatigue is a sub-health state of a human body with a series of adverse or uncomfortable symptoms under the conditions of excessive fatigue and physical strength overdraft. Fatigue is a normal physiological response of the human body, but long-term fatigue is a very dangerous state. At present, due to the influence of new social and economic trends, a large number of people in a fatigue state exist, and most of the people are successful people, people with high working and learning pressure such as white-collar class and the like. The long-term fatigue state reduces the energy and material reserves of the human body of the people, the peroxidation garbage is accumulated in cells in large quantity, the normal immune system is affected, the resistance is reduced, and then various acute and chronic diseases are induced.
According to traditional Chinese medicine, fatigue belongs to the categories of diseases such as consumptive disease, internal injury of spleen and stomach, dizziness, insomnia and pain, and is caused by qi disorder and qi and blood deficiency of internal organs of a human body, and the treatment mainly aims at replenishing vital essence, preserving health and nourishing yin and warming and tonifying. The product is developed according to the theory of traditional Chinese medicine and by combining with modern medicine and pharmacology, and achieves the purpose of improving the life quality of fatigue patients.
Disclosure of Invention
The invention provides a combined preparation with the functions of invigorating primordial qi, warming, nourishing yin and preserving health and a preparation method thereof.
The scheme of the invention is as follows:
a combined preparation with the effects of invigorating primordial qi, warming, nourishing yin and preserving health comprises the following raw materials in parts by weight:
10-25% of nostoc sphaeroides;
1-4% of adenophora elata L;
2-5% of lycoris radiate;
8-16% of prepared rehmannia root;
1-3% of deerhorn glue;
2-4% of cinnamon;
0.5-1% of angelica;
0.2-0.8% of radix angelicae;
0.4-0.6% of white peony root;
0.3-0.7% of bighead atractylodes rhizome;
2-3% of honey-fried licorice root;
4-9% of rock sugar;
30-65% of water;
2-6% of yellow wine;
3-6% of an additive.
The preferable technical scheme comprises the following raw materials in parts by weight:
23% of nostoc sphaeroides;
2% of apricot leaf and root of straight ladybell;
3 percent of lycoris radiate;
12% of prepared rehmannia root;
2% of deerhorn glue;
3% of cinnamon;
0.7 percent of angelica;
0.6 percent of angelica dahurica;
0.5 percent of white paeony root;
0.6 percent of white atractylodes rhizome;
2.5 percent of honey-fried licorice root;
8% of rock sugar;
4% of yellow wine;
60% of water;
4% of additive.
As a preferred technical scheme, the additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
Preferably, the water is one of distilled water and spring water.
The invention also provides a method for preparing the combined preparation for invigorating primordial qi, warming, nourishing yin and preserving health, which comprises the following steps:
1) soaking fresh nostoc sphaeroids kutz in water for 2-3h, draining, pulping the drained nostoc sphaeroids kutz in a juicer, and filtering to obtain nostoc sphaeroids kutz liquid for later use;
2) respectively cleaning and crushing 1-4% by weight of adenophora giraldii, 2-5% by weight of lycoris radiata, 8-16% by weight of prepared rehmannia root, 2-4% by weight of cinnamon, 0.5-1% by weight of angelica sinensis, 0.2-0.8% by weight of angelica dahurica, 0.4-0.6% by weight of radix paeoniae alba, 0.3-0.7% by weight of rhizoma atractylodis macrocephalae and 2-3% by weight of honey-fried licorice root, mixing, softening for 2-3h in an environment with the temperature of 30-60 ℃, spraying warm water 30-50% by weight of Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid;
3) adding 8-16% of first entrainer into carbon dioxide fluid, controlling the extraction temperature to be 80-100 ℃, the pressure to be 12-18MPa, and the time to be 1-1.5h, separating the extract, and allowing the rest to enter the next step;
4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 30-50% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 90-110 ℃, the pressure to be 25-30MPa, and the time to be 1.5-2h, separating the extract, and allowing the rest to enter the next step;
5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 60-70% of third entrainer into the carbon dioxide fluid, further extracting at the extraction temperature of 100-120 ℃, under the pressure of 25-30MPa for 1-2h, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid;
6) melting 1-3% by weight of deerhorn glue, 2-6% by weight of yellow wine and 4-9% by weight of crystal sugar, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 10-25% by weight of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 3-6% by weight of an additive into the mixed solution, and injecting 30-65% by weight of water to obtain the combined preparation with the effects of tonifying primordial qi, warming and nourishing yin and preserving health.
As a preferable technical scheme, the modifying agent in the step 2) is a mixture of ethanol, lecithin and stearic acid.
As a preferable technical solution, the first carrier in step 3) is ethyl acetate.
As a preferred technical solution.
As a preferable technical solution, the second carrier in the step 4) is acetone.
As a preferable technical scheme, the third carrying agent in the step 5) is a mixture of ethanol and acetonitrile.
As a preferred technical scheme, the additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
Due to the adoption of the technical scheme, the composite preparation with the effects of tonifying vitality, warming, nourishing yin and preserving health comprises the following steps of 1) adding fresh nostoc sphaeroids kutz into water for soaking for 2-3h, draining after soaking, putting the drained nostoc sphaeroids kutz into a juicer, pulping and filtering to obtain nostoc liquid for later use; 2) respectively cleaning and crushing 1-4% by weight of adenophora giraldii, 2-5% by weight of lycoris radiata, 8-16% by weight of prepared rehmannia root, 2-4% by weight of cinnamon, 0.5-1% by weight of angelica sinensis, 0.2-0.8% by weight of angelica dahurica, 0.4-0.6% by weight of radix paeoniae alba, 0.3-0.7% by weight of rhizoma atractylodis macrocephalae and 2-3% by weight of honey-fried licorice root, mixing, softening for 2-3h in an environment with the temperature of 30-60 ℃, spraying warm water 30-50% by weight of Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid; 3) adding 8-16% of first entrainer into carbon dioxide fluid, controlling the extraction temperature to be 80-100 ℃, the pressure to be 12-18MPa, and the time to be 1-1.5h, separating the extract, and allowing the rest to enter the next step; 4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 30-50% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 90-110 ℃, the pressure to be 25-30MPa, and the time to be 1.5-2h, separating the extract, and allowing the rest to enter the next step; 5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 60-70% of third entrainer into the carbon dioxide fluid, further extracting at the extraction temperature of 100-120 ℃, under the pressure of 25-30MPa for 1-2h, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid; 6) melting 1-3% by weight of deerhorn glue, 2-6% by weight of yellow wine and 4-9% by weight of crystal sugar, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 10-25% by weight of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 3-6% by weight of an additive into the mixed solution, and injecting 30-65% by weight of water to obtain the combined preparation with the effects of tonifying primordial qi, warming and nourishing yin and preserving health.
The invention has the advantages that: the invention has long quality guarantee time, is suitable for the taste of the public, has aromatic temperature and mellow taste, adopts pure natural medicinal and edible green plant raw materials, has no pigment and any essence substance, has faint scent, sweetness, moistness and mellow flavor, can tonify qi and blood, adjust yin and yang, is convenient to use, strengthens the body resistance to eliminate pathogenic factors, and prevents exogenous diseases; the Chinese medicinal composition has the effects of warming and moistening, tonifying primordial essence and yin, balancing sexual and taste, tonifying qi, preserving health, nourishing liver and kidney, fully regulating functions of the liver and the kidney and achieving the purpose of improving the life quality of a patient with fatigue.
Detailed Description
In order to make up for the above deficiencies, the invention provides a combined preparation with the effects of invigorating primordial qi, warming, nourishing yin and preserving health and a preparation method thereof so as to solve the problems in the background technology.
A combined preparation with the effects of invigorating primordial qi, warming, nourishing yin and preserving health comprises the following raw materials in parts by weight:
10-25% of nostoc sphaeroides;
1-4% of adenophora elata L;
2-5% of lycoris radiate;
8-16% of prepared rehmannia root;
1-3% of deerhorn glue;
2-4% of cinnamon;
0.5-1% of angelica;
0.2-0.8% of radix angelicae;
0.4-0.6% of white peony root;
0.3-0.7% of bighead atractylodes rhizome;
2-3% of honey-fried licorice root;
4-9% of rock sugar;
30-65% of water;
2-6% of yellow wine;
3-6% of an additive.
Comprises the following raw materials in parts by weight:
23% of nostoc sphaeroides;
2% of apricot leaf and root of straight ladybell;
3 percent of lycoris radiate;
12% of prepared rehmannia root;
2% of deerhorn glue;
3% of cinnamon;
0.7 percent of angelica;
0.6 percent of angelica dahurica;
0.5 percent of white paeony root;
0.6 percent of white atractylodes rhizome;
2.5 percent of honey-fried licorice root;
8% of rock sugar;
4% of yellow wine;
60% of water;
4% of additive.
The additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
The water is distilled water or spring water.
The invention also provides a method for preparing the combined preparation for invigorating primordial qi, warming, nourishing yin and preserving health, which comprises the following steps:
1) soaking fresh nostoc sphaeroids kutz in water for 2-3h, draining, pulping the drained nostoc sphaeroids kutz in a juicer, and filtering to obtain nostoc sphaeroids kutz liquid for later use;
2) respectively cleaning and crushing 1-4% by weight of adenophora giraldii, 2-5% by weight of lycoris radiata, 8-16% by weight of prepared rehmannia root, 2-4% by weight of cinnamon, 0.5-1% by weight of angelica sinensis, 0.2-0.8% by weight of angelica dahurica, 0.4-0.6% by weight of radix paeoniae alba, 0.3-0.7% by weight of rhizoma atractylodis macrocephalae and 2-3% by weight of honey-fried licorice root, mixing, softening for 2-3h in an environment with the temperature of 30-60 ℃, spraying warm water 30-50% by weight of Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid;
3) adding 8-16% of first entrainer into carbon dioxide fluid, controlling the extraction temperature to be 80-100 ℃, the pressure to be 12-18MPa, and the time to be 1-1.5h, separating the extract, and allowing the rest to enter the next step;
4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 30-50% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 90-110 ℃, the pressure to be 25-30MPa, and the time to be 1.5-2h, separating the extract, and allowing the rest to enter the next step;
5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 60-70% of third entrainer into the carbon dioxide fluid, further extracting at the extraction temperature of 100-120 ℃, under the pressure of 25-30MPa for 1-2h, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid;
6) melting 1-3% by weight of deerhorn glue, 2-6% by weight of yellow wine and 4-9% by weight of crystal sugar, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 10-25% by weight of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 3-6% by weight of an additive into the mixed solution, and injecting 30-65% by weight of water to obtain the combined preparation with the effects of tonifying primordial qi, warming and nourishing yin and preserving health.
The modifier in the step 2) is a mixture of ethanol, lecithin and stearic acid.
The first entrainer in the step 3) is ethyl acetate.
The second entrainer in the step 4) is acetone.
The third carrier in the step 5) is a mixture of ethanol and acetonitrile.
The additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Example 1:
1) soaking fresh nostoc sphaeroids kutz in water for 2 hours, draining, pulping the drained nostoc sphaeroids kutz in a juicer, and filtering to obtain nostoc sphaeroids kutz liquid for later use;
2) respectively cleaning and crushing 1% of adenophora giraldii, 2% of lycoris radiata, 8% of prepared rehmannia root, 2% of cinnamon, 0.5% of angelica, 0.2% of angelica dahurica, 0.4% of white peony root, 0.3% of bighead atractylodes rhizome and 2% of honey-fried licorice root by weight into powder of 100 mu m, mixing, softening for 2 hours in an environment with the temperature of 30 ℃, spraying warm water accounting for 30% of the weight of the Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid;
3) adding 8% of first entrainer into carbon dioxide fluid, controlling the extraction temperature at 80 ℃, the pressure at 12MPa and the time at 1h, separating the extract, and allowing the rest to enter the next step;
4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 30% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 90 ℃, the pressure to be 25MPa, and the time to be 1.5h, separating the extract, and allowing the rest to enter the next step;
5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 60% of third entrainer into the carbon dioxide fluid, further extracting at 100 ℃ under 25MPa for 1h, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid;
6) melting 1% of deerhorn glue, 2% of yellow wine and 4% of rock candy by weight, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 10% of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 3% of additives into the mixed solution, and injecting 30% of water by weight to obtain the combined preparation for replenishing vital energy, warming and nourishing yin and preserving health.
The modifier in the step 2) is a mixture of ethanol, lecithin and stearic acid.
The first entrainer in the step 3) is ethyl acetate.
The second entrainer in the step 4) is acetone.
The third carrier in the step 5) is a mixture of ethanol and acetonitrile.
The additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
Example 2:
1) soaking fresh nostoc sphaeroids kutz in water for 3 hours, draining, pulping the drained nostoc sphaeroids kutz in a juicer, and filtering to obtain nostoc sphaeroids kutz liquid for later use;
2) respectively cleaning and crushing 4% of adenophora giraldii, 5% of lycoris radiata, 16% of prepared rehmannia root, 4% of cinnamon, 1% of angelica, 0.8% of angelica dahurica, 0.6% of white peony root, 0.7% of bighead atractylodes rhizome and 3% of honey-fried licorice root by weight, mixing the materials after 1mm of powder is mixed, then placing the mixture in an environment with the temperature of 60 ℃ for softening for 3 hours, spraying warm water accounting for 50% of the weight of the Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid;
3) adding 16% of first entrainer into carbon dioxide fluid, controlling the extraction temperature at 100 ℃, the pressure at 18MPa, and the time at 1.5h, separating the extract, and allowing the rest to enter the next step;
4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 50% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 110 ℃, the pressure to be 30MPa, and the time to be 2h, separating the extract, and allowing the rest to enter the next step;
5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 70% of third entrainer into the carbon dioxide fluid, further extracting at the extraction temperature of 120 ℃, under the pressure of 30MPa for 2 hours, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid;
6) melting 3% of deerhorn glue, 6% of yellow wine and 9% of rock candy by weight, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 25% of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 6% of additives into the mixed solution, and injecting 65% of water by weight to obtain the combined preparation for replenishing vital energy, warming and nourishing yin and preserving health.
The modifier in the step 2) is a mixture of ethanol, lecithin and stearic acid.
The first entrainer in the step 3) is ethyl acetate.
The second entrainer in the step 4) is acetone.
The third carrier in the step 5) is a mixture of ethanol and acetonitrile.
The additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
Example 3:
1) soaking fresh nostoc sphaeroids kutz in water for 2.5h, draining, pulping the drained nostoc sphaeroids kutz in a juicer, and filtering to obtain nostoc sphaeroids kutz liquid for later use;
2) respectively cleaning and crushing 2% of adenophora giraldii, 3% of lycoris radiata, 12% of prepared rehmannia root, 3% of cinnamon, 0.7% of angelica, 0.6% of angelica dahurica, 0.5% of white peony root, 0.6% of bighead atractylodes rhizome and 2.5% of honey-fried licorice root by weight, mixing the materials after 1mm of powder is mixed, then placing the mixture in an environment with the temperature of 40 ℃ for softening for 3 hours, spraying warm water accounting for 45% of the weight of the Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid;
3) adding 10% of first entrainer into carbon dioxide fluid, controlling the extraction temperature at 90 ℃, the pressure at 15MPa, and the time at 1.5h, separating the extract, and allowing the rest to enter the next step;
4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 40% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 100 ℃, the pressure to be 28MPa, and the time to be 2h, separating the extract, and allowing the rest to enter the next step;
5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 65% of third entrainer into the carbon dioxide fluid, further extracting at the extraction temperature of 110 ℃, under the pressure of 28MPa for 2 hours, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid;
6) melting 2% of deerhorn glue, 4% of yellow wine and 8% of rock candy by weight, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 23% of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 4% of additives into the mixed solution, and injecting 60% of water by weight to obtain the combined preparation with the effects of invigorating primordial qi, warming and nourishing yin and preserving health.
The modifier in the step 2) is a mixture of ethanol, lecithin and stearic acid.
The first entrainer in the step 3) is ethyl acetate.
The second entrainer in the step 4) is acetone.
The third carrier in the step 5) is a mixture of ethanol and acetonitrile.
The additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
Taking the preparation in example 3, taste evaluation was performed on 50 persons, of which 42 persons evaluated that the taste was excellent and very good, 5 persons felt good, and 3 persons felt normal.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (10)

1. A combined preparation with the effects of invigorating primordial qi, warming, nourishing yin and preserving health is characterized by comprising the following raw materials in parts by weight:
10-25% of nostoc sphaeroides;
1-4% of adenophora elata L;
2-5% of lycoris radiate;
8-16% of prepared rehmannia root;
1-3% of deerhorn glue;
2-4% of cinnamon;
0.5-1% of angelica;
0.2-0.8% of radix angelicae;
0.4-0.6% of white peony root;
0.3-0.7% of bighead atractylodes rhizome;
2-3% of honey-fried licorice root;
4-9% of rock sugar;
30-65% of water;
2-6% of yellow wine;
3-6% of an additive.
2. The composition with the effects of warming, nourishing yin and preserving health as claimed in claim 1, which comprises the following raw materials in parts by weight:
23% of nostoc sphaeroides;
2% of apricot leaf and root of straight ladybell;
3 percent of lycoris radiate;
12% of prepared rehmannia root;
2% of deerhorn glue;
3% of cinnamon;
0.7 percent of angelica;
0.6 percent of angelica dahurica;
0.5 percent of white paeony root;
0.6 percent of white atractylodes rhizome;
2.5 percent of honey-fried licorice root;
8% of rock sugar;
4% of yellow wine;
60% of water;
4% of additive.
3. The combination preparation for replenishing vital essence and preserving health as claimed in claim 1 or 2, wherein: the additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
4. The combination preparation for replenishing vital essence and preserving health as claimed in claim 1 or 2, wherein: the water is distilled water or spring water.
5. A method for preparing the combined preparation for invigorating primordial qi, warming, nourishing yin and preserving health of claim 1, which comprises the following steps:
1) soaking fresh nostoc sphaeroids kutz in water for 2-3h, draining, pulping the drained nostoc sphaeroids kutz in a juicer, and filtering to obtain nostoc sphaeroids kutz liquid for later use;
2) respectively cleaning and crushing 1-4% by weight of adenophora giraldii, 2-5% by weight of lycoris radiata, 8-16% by weight of prepared rehmannia root, 2-4% by weight of cinnamon, 0.5-1% by weight of angelica sinensis, 0.2-0.8% by weight of angelica dahurica, 0.4-0.6% by weight of radix paeoniae alba, 0.3-0.7% by weight of rhizoma atractylodis macrocephalae and 2-3% by weight of honey-fried licorice root, mixing, softening for 2-3h in an environment with the temperature of 30-60 ℃, spraying warm water 30-50% by weight of Chinese herbal medicines, performing supercritical carbon dioxide fluid extraction on the treated mixture, and adding a modifier into the carbon dioxide fluid;
3) adding 8-16% of first entrainer into carbon dioxide fluid, controlling the extraction temperature to be 80-100 ℃, the pressure to be 12-18MPa, and the time to be 1-1.5h, separating the extract, and allowing the rest to enter the next step;
4) introducing carbon dioxide fluid added with the modifier on the basis of the step 3), adding 30-50% of second entrainer into the carbon dioxide fluid, further extracting, controlling the extraction temperature to be 90-110 ℃, the pressure to be 25-30MPa, and the time to be 1.5-2h, separating the extract, and allowing the rest to enter the next step;
5) introducing carbon dioxide fluid added with the modifier on the basis of the step 4), adding 60-70% of third entrainer into the carbon dioxide fluid, further extracting at the extraction temperature of 100-120 ℃, under the pressure of 25-30MPa for 1-2h, separating the extract from the Chinese herbal medicines, and then purifying to obtain purified liquid;
6) melting 1-3% by weight of deerhorn glue, 2-6% by weight of yellow wine and 4-9% by weight of crystal sugar, blending with the extracting solution in the step 5) to obtain a mixed solution, adding 10-25% by weight of nostoc sphaeroides liquid in the step 1) into the mixed solution, adding 3-6% by weight of an additive into the mixed solution, and injecting 30-65% by weight of water to obtain the combined preparation with the effects of tonifying primordial qi, warming and nourishing yin and preserving health.
6. The method of claim 5, wherein the preparation is a composition for invigorating primordial qi, warming, nourishing yin, and preserving health, and comprises: the modifier in the step 2) is a mixture of ethanol, lecithin and stearic acid.
7. The method of claim 5, wherein the preparation is a composition for invigorating primordial qi, warming, nourishing yin, and preserving health, and comprises: the first entrainer in the step 3) is ethyl acetate.
8. The method of claim 5, wherein the preparation is a composition for invigorating primordial qi, warming, nourishing yin, and preserving health, and comprises: the second entrainer in the step 4) is acetone.
9. The method of claim 5, wherein the preparation is a composition for invigorating primordial qi, warming, nourishing yin, and preserving health, and comprises: the third carrier in the step 5) is a mixture of ethanol and acetonitrile.
10. The method of claim 5, wherein the preparation is a composition for invigorating primordial qi, warming, nourishing yin, and preserving health, and comprises: the additive comprises one or more of citric acid, edible gum, potassium sorbate and vanillin.
CN202110440274.2A 2021-04-23 2021-04-23 A composition preparation with effects of invigorating primordial qi, warming, nourishing yin and promoting health, and its preparation method Pending CN113197978A (en)

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Publication number Priority date Publication date Assignee Title
CN101805687A (en) * 2010-04-14 2010-08-18 杨宇 Radix rehmanniae health care wine and production method thereof
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CN107998685A (en) * 2017-11-26 2018-05-08 长沙无道工业设计有限公司 Chinese herbal medicine extracting process

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CN101805687A (en) * 2010-04-14 2010-08-18 杨宇 Radix rehmanniae health care wine and production method thereof
CN102579669A (en) * 2012-03-05 2012-07-18 宁夏紫荆花制药有限公司 Chinese medicinal composition for nourishing qi and blood and conditioning menstruation and preparation method thereof
CN107998685A (en) * 2017-11-26 2018-05-08 长沙无道工业设计有限公司 Chinese herbal medicine extracting process

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