CN105288427A - Traditional Chinese medicine pill used for treating liver-depression and qi-stagnation type gastric retention and preparation method thereof - Google Patents

Traditional Chinese medicine pill used for treating liver-depression and qi-stagnation type gastric retention and preparation method thereof Download PDF

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CN105288427A
CN105288427A CN201510821823.5A CN201510821823A CN105288427A CN 105288427 A CN105288427 A CN 105288427A CN 201510821823 A CN201510821823 A CN 201510821823A CN 105288427 A CN105288427 A CN 105288427A
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stagnation
fructus
pot
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powder
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李春雷
刘艳丽
吴美英
侯小霞
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Abstract

The invention discloses a traditional Chinese medicine pill used for treating liver-depression and qi-stagnation type gastric retention and a preparation method thereof, belonging to the field of traditional Chinese medicine. The effective component of the traditional Chinese medicine pill comprises the following raw materials: Paniculate Microcos, millet sprout, fruit of fiverleaf akebia, Dangshen, Chinese fevervine herb and root, tuber of dwarf lilyturf, raspberry root, bighead atractylodes rhizome, loquat leaf, immature fruit of Trifoliate-orange, Emmenopterys henryi, Chinese-date, wild magnolia cortex, dried orange peel, cluster cardamom, fingered citron, Oroxylum indicum, immature bitter orange, grass node in stomach of ox and goat, Ligusticum wallichii, dill fruit, liquorice, chicken's gizzard membrane and aspongopus. According to the invention, medical properties of the selected medicinal materials are compatible and complementary; the prepared traditional Chinese medicine pill treats gastric retention directed at causes, is capable of coursing the liver, harmonizing the stomach, invigorating the spleen, benefiting qi, warming the spleen, whetting the appetite, promoting digestion, eliminating indigestion, depressing qi, regulating middle energizer, calming adverse-rising energy, controlling nausea and vomiting, rectifying qi and relieving pain and has good absorption effect, substantial curative effect, no toxic and side effect and no clinical adverse reaction; and according to clinical verification results, the traditional Chinese medicine pill has a high cure rate in treatment of liver-depression and qi-stagnation type gastric retention.

Description

A kind of medicine pill and preparation method being used for the treatment of caused by hepatic stagnation qi stagnation gastric retention
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine pill and the preparation method that are used for the treatment of caused by hepatic stagnation qi stagnation gastric retention.
Background technology
Gastric retention, also known as delayed gastric emptying, refers to stagnant the depositing of gastric content and not emptying in time.All food vomitting absorption in the past in 4-6 hour, or more than 8 hours on an empty stomach, record stomach residual quantity >200ml person, all prompting has gastric retention to exist.Primary disease is a common frequently-occurring disease, without age and differentiation in different regions, women seemingly comparatively male be many.Vomiting is the main manifestations of primary disease, day and night all can occur, and one day 1 to for several times.Vomitus is often dyspepsia, generally not containing bile.Abdeminal pain and pain are also common.Stomachache can be dull pain, angor or burning pain.After vomiting, symptom temporarily can obtain alleviation.
Because gastrointestinal motility disorder is considered to the principal element of functional gastric retention, doctor trained in Western medicine removes general symptomatic treatment as low-residue diet usually for primary disease, vitimin supplement and trace element and correct outside water, electrolyte and acid base imbalance, as given, in addition symptomatic treatment, promotes that gastric motility class medicine (metoclopramide, motilium etc.) is treated.At present, though western medicine quick result, healing is longer for the course for the treatment of completely, and Long-term taking medicine can produce drug dependence and some side effect.
The traditional Chinese medical science thinks that primary disease main pathogenesis is: The spleen has the function to transport and transform nutrients spreading, and normal to be upgraded to, stomach receiving food and drink becomes thoroughly decomposed, suitable to reduce to, and taste are total pivot of digestion; Exopathogen visitor is in taste, and taste are injured; Depression of liver-QI, horizontal criminal's taste; Of excessive eating and drinking, consumption damaging the spleen and stomach is burnt, and the taste development of evil in febrile disease is too late; Ferritic weakness of the spleen and stomach, transporting of being received is unable, all can cause incoordination between the spleen and stomach, and lifting is lacked of proper care and occurs QI rising in reverse order vomiting and nausea, abdominal distention gastralgia.Therefore treating according to categorical identification in terms of causes of disease is the basic rule for the treatment of of Chinese traditional treatment primary disease, primary disease is divided into that exopathogen violates stomach, deficiency of spleen-QI and stomach-QI, Deficiency and coldness of spleen and stomach, deficiency of stomach-Yin, the several types such as Jiao, stagnation of QI due to depression of the liver, phlegm resistance treats in dyspepsia by the traditional Chinese medical science usually, and effect is better.Chinese medicine of the present invention is treated mainly for caused by hepatic stagnation qi stagnation gastric retention, have in dispersing the stagnated liver-QI for regulating the stomach, invigorating the spleen and benefiting QI, warming the spleen appetizing, promoting digestion and removing stagnation, lower controlled atmosphere, effect of stopping nausea and vomiting by lowering the adverse flow of QI, regulating QI to relieve pain, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to caused by hepatic stagnation qi stagnation gastric retention cure rate through clinical verification.
Summary of the invention
The invention provides a kind of medicine pill and the preparation method that are used for the treatment of caused by hepatic stagnation qi stagnation gastric retention, have in dispersing the stagnated liver-QI for regulating the stomach, invigorating the spleen and benefiting QI, warming the spleen appetizing, promoting digestion and removing stagnation, lower controlled atmosphere, effect of stopping nausea and vomiting by lowering the adverse flow of QI, regulating QI to relieve pain, cure the disease and ask source treating both the principal and secondary aspects of a disease, for caused by hepatic stagnation qi stagnation gastric retention, there is good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine pill for caused by hepatic stagnation qi stagnation gastric retention, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine pill of caused by hepatic stagnation qi stagnation gastric retention, comprise following processing step:
(1) Folium Microcoris paniculatae, Fructus Setariae Germinatus, Radix Ophiopogonis, Radix Rubi, the Rhizoma Atractylodis Macrocephalae, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Emmenopterys henryi oliv., Fructus Jujubae, wild Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus, Fructus Citri Sarcodactylis, Semen Oroxyli, Fructus anethi, Radix Glycyrrhizae are cleaned, dry rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Fructus Akebiae, Herba Paederiae are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(4) get Folium Eriobotryae cut tobacco, add cooked Mel and certain amount of boiling water, mix thoroughly, slightly vexed, put the interior slow fire of pot and fry to tack-free for spending, taking-up, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(5) first being removed by wheat bran in the even pot in heating, when marquis's cigarette is emerged, adding Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, and cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(6) be placed in pot by Calcucus Stomachi Bovis, slow fire heats, and constantly stir-fries, and take out time crisp to color burn quality, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(7) getting Rhizoma Chuanxiong sheet yellow wine sprays evenly, slightly vexed, and putting in pot and frying extremely micro-Jiao is degree, and taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(8) first sand is put into pot to make popular, then the Endothelium Corneum Gigeriae Galli cleaned is put into pot, stir and heave to brown color or coke yellow, take out with slow fire, sieve shakeout, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(9) getting clean Aspongopus puts in pot, and with slow fire heating, fry to when having fragrance to overflow, take out, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(10) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), step (9), add after refined honey stirs, be prepared as the pill of every 3g.
The property of medicine of the present invention's Chinese medicine used is as follows:
Folium Microcoris paniculatae: sour in the mouth; Light; Property is put down.Return spleen channel.Clearing away heat-damp and promoting diuresis; Stomach invigorating disappears stagnant.Cure mainly cold, fever; Jaundice; Inappetence; Dyspepsia; Abdominal distention; Have loose bowels; Skin infection; Centipete bite." book on Chinese herbal medicine asks former ": " separate all distention of the abdomen caused by various parasites poison of drug, heat clearing away, removing food stagnancy is eaten, jaundice."
Fructus Setariae Germinatus: sweet in the mouth; Flat.Return spleen; Stomach warp.Promoting digestion and removing stagnation; Spleen benefiting and stimulating the appetite.Cure mainly: food stagnation is stagnated; Distension is had loose bowels; Insufficiency of the spleen few food; Beriberi edema." Bencao Jingshu ": tiller rice and rice tiller are also.The property of tool biochemistry, thus be digestion-promoting spleen-invigorating, appetizing and in key medicine, taste and then in from pestilence, gas under, heat is from except also.
Fructus Akebiae: hide micro-hardship, property is put down.Return liver, stomach, urinary bladder channel.Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.Cure mainly stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor." Shaanxi Chinese herbal medicine ": Shugan Yishen, invigorating the spleen and regulating the stomach.Control dyspepsia, stomachache, dysentery, hernia, uterus drops.
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung; Supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach; Anorexia and loose stool; Limbs fatigue; The deficiency of the lung is breathed with cough; To breathe hard spontaneous perspiration; The all cards of deficiency of both QI and blood." moral joins book on Chinese herbal medicine " carries: " lung heat clearing gold, invigorating primordial QI, opens sound, helps biceps." modern medicine study confirms; Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; on excited and suppress two kinds of nervous process to have impact, can raise erythrocyte, hemoglobin, reticulocyte, also have the effect of slow down aging and antioxidation, radioprotective, blood pressure lowering.
Herba Paederiae: sweet in the mouth acid; Property is put down.GUIXIN; Liver; Spleen; Kidney channel.Expelling wind and removing dampness, dyspepsia and intestinal stasis relieving, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain.Dispelling the wind and dampness pathogens arthralgia pain; Dyspeptic abdominal distention; Infantile malnutrition; Diarrhoea; Dysentery; Heatstroke; Jaundice; Hepatitis; Hepatosplenomegaly; Cough; Scrofula; Intestinal carbuncle; Innominate toxic swelling; Foot damp-edema is rotten; Burn and scald; Eczema; Dermatitis; Traumatic injury; Serpentis flood dragon scorpion sting.Chongqing medical herbs: spleen invigorating dehumidifies, QI invigorating tonify deficiency.Be usually used in children's thin and weak, the weak deficiency of vital energy of spleen, food stagnation infantile malnutrition, and adult's deficiency of vital energy edema, tympanites, tinnitus, diarrhoea, the enuresis, the weak leucorrhea of women, dry sick.And weak impairment caused by overstrain, dysentery of deficiency type, sub-scrofula of itching due to deficiency of vital energy unhealed.
Radix Ophiopogonis: sweet in the mouth; Micro-hardship; Cold nature.GUIXIN; Lung; Stomach warp.YIN nourishing and the production of body fluid promoting; Lung moistening clears away heart-fire.Cure mainly dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation." Mingyi Bielu " carries: " Radix Ophiopogonis treats heavy sensation of the body icteric sclera, and rami cardiaci inferiores is full, asthenia exopathogenic heat, xerostomia excessive thirst, anti-nausea, and more flaccidity falls, and reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protects god, determine lung qi, settling five organs, makes us fertile strong." modern medicine study confirms; contain the compositions such as multiple steroid saponin, carotene, phlegmatic temperament, saccharide, stigmasterol Radix Ophiopogonis; have leukocyte increasing; extend the effect of antibody life period; improve immunologic function and nucleic acid synthetic ratio; the generation of the immune materials such as enhancing antibody, complement, interferon, lysozyme simultaneously, have and strengthen healthy energy, strengthen anti-heresy effect.
Radix Rubi: bitter in the mouth; Property is put down.Return stomach; Liver Channel.Wind-expelling pain-stopping, improving acuity of vision and removing nebula, stomach function regulating preventing or arresting vomiting.Cure mainly toothache, rheumatic arthralgia, corneal nebula, vomiting.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement." herbal classic is met former " carries: " art, raw with there being dehumidifying benefit dry, expectorant diuretic, controls anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, blood between loose waist umbilicus, and chong channel is disease, the merit of inverse gas pain in the abdomen; Make ripe, have and middle QI invigorating, slake thirst and help produce saliva, hidroschesis heat extraction, enters diet, antiabortive effect." modern medicine study confirms, the Rhizoma Atractylodis Macrocephalae has diuresis, blood sugar lowering, strong, anticoagulation, antitumor, antibacterial, the effect that promotes hemopoietic and protein synthesis.
Folium Eriobotryae: bitter in the mouth; Pungent; Cold in nature; Nontoxic.Enter lung; The heart; Stomach warp.Clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.Compendium of Material Medica: Folium Eriobotryae, controls the disease of lung stomach, mostly gets the merit ear of its therapeutic method to keep the adverse QI flowing downwards.Under gas then fire to fall expectorant suitable, and inverse person is not inverse, and habitual vomiter does not vomit, and thirsty person is thirsty, and the person of coughing does not cough.Modern medicine study confirms, amygdalin contained by Folium Eriobotryae is decomposited Microamounts of Hydrogen cyanic acid at lower digestive tract by microbial enzyme, the latter has sedation to respiratory center, therefore have antiasthmatic effect effect, on Carrageenan edema has powerful inhibitory action, and contained sesquiterpene glycoside and polyhydroxy triterpene glycoside significantly can reduce blood glucose.
Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus): acrid in the mouth; Bitter; Warm in nature.Return liver; Stomach warp.Dispersing the stagnated liver-QI for regulating the stomach; Regulating QI to relieve pain; Removing food stagnancyization is stagnant.Cure mainly fullness and distention in the chest and hypochondrium; Abdominal distention; Breast lumps; Hernia pain; Painful and swollen testis; Traumatic injury; Food stagnation; Constipation; Uterine prolapse." Chinese herbal medicine is commonly used in Shanghai ": promoting the circulation of QI, stomach invigorating, relieving constipation.Control stomach distension, dyspepsia, constipation, uterine prolapse, tuberculosis of breast.
Emmenopterys henryi oliv.: acrid in the mouth; Sweet; Slightly warm in nature.Return stomach warp.Stomach function regulating in wet; Stopping nausea and vomiting by lowering the adverse flow of QI.Cure mainly regurgitation; Vomiting; Singultus.
Fructus Jujubae: sweet in the mouth; Temperature.Return spleen; Stomach warp.Tonifying the spleen and stomach; Replenishing QI and blood; Tranquilizing mind; Battalion is adjusted to defend; And the property of medicine.Cure mainly weakness of the spleen and stomach; Insufficiency of vital energy and blood; Anorexia and loose stool; Fatigue and weakness; Palpitation and insomnia; Woman hysteria; Disharmony of nutrient QI with defensive QI." book on Chinese herbal medicine remittance speech ": Shen Shi says, and the sweet profit cream of this medicine coagulates, kind nourishing YIN sun, QI and blood, body fluid, venation, muscle Yu, bone marrow, and all are deficient, without shoulding not it.As imperial Tan Fang controls palpitation with fear palpitation with a distress feeling, dimly forgetful, will meaning stupor, spirit is not kept, or middle gas discord, poor appetite, and hundred body lazynesses are heavy, and muscle is thin, and the card that this belongs to the heart, spleen two hides unit god loss, must control it with Fructus Jujubae.Assistant Pericarpium Citri Reticulatae, adjusts the empty stagnant expectorant of the smooth middle part of gastric cavity.
Wild Cortex Magnoliae Officinalis: bitter in the mouth; Pungent; Warm in nature.Warming middle-JIAO is regulated the flow of vital energy; Promoting digestion and invigorating the stomach.Cure mainly chronic gastritis; Dyspepsia; Vomiting; Abdominal distention is suffered from abdominal pain; Diarrhoea.
Pericarpium Citri Reticulatae: acrid in the mouth; Sweet; Cold in nature.Enter spleen; Stomach warp.The therapeutic method to keep the adverse QI flowing downwards; In tune; Reduce phlegm; Relieving alcoholic intoxication.Cure mainly drinking and eating irregularly; Upper gas stuffy sensation with restlessness; Get sick from drinking too much wine thirsty." Japan hanako materia medica " carries: " skin is processed and is made soup, can alcoholic intoxication and wine thirsty, typhoid fever diet recurrence caused by overexertion person, densely decocts juice clothes." medicine clinical research shows; the Hesperidin contained by Pericarpium Citri Reticulatae can suppress gastric ulcer; reduce capillary permeability; have adjustment gastrointestinal function and antiinflammatory action; its volatile oil has eliminating the phlegm, relievings asthma, facilitating digestion liquid secretion and get rid of the effects such as enteral pneumatosis, also has coronary artery dilator in addition, reduces blood pressure and the effect such as function of gallbladder promoting.
Fructus Amomi Rotundus: acrid in the mouth; Warm in nature.Return lung; Spleen; Stomach warp.Removing dampness circulation of qi promoting; Warming middle-JIAO to arrest vomiting; Appetite-stimulating indigestion-relieving.Cure mainly retention of damp leading to blockage of QI; Incoordination between the spleen and stomach; Distension and fullness in the abdomen; Anorexia; Hygropyrexia from the beginning of; Uncomfortable in chest not hungry; Gastrofrigid vomiting; Food stagnation does not disappear." Bencao Jingshu ": Fructus Amomi Rotundus, main accumulation of pathogenic cold gas and hinder cold tell inverse, because of cold regurgitation.The warm thing that can disappear, therefore main rapid digestion of food again; Temperature can be passed through, therefore the main therapeutic method to keep the adverse QI flowing downwards.Dong Yuan is in order to gas stagnant in loose lung, and wide diaphragm feed, removes white of the eye nebula film, and loose stagnant merit also.Modern pharmacological research proves: Fructus Amomi Rotundus has bacteriostasis, antiasthmatic effect, and can promote gastric secretion, excited intestinal motility, drives away enteral pneumatosis, and suppresses enteral abnormal fermentation.
Fructus Citri Sarcodactylis: acrid in the mouth; Bitter; Warm in nature.Enter liver; Stomach; Spleen; Lung meridian.Liver-smoothing, qi-regulating; Stomach function regulating reduces phlegm.Cure mainly the hypochondriac pain of depression of liver-QI; Breast is vexed; Incoordination between the liver and stomach; The abdominal distention of stagnation of QI in spleen and stomach; Yuan gas; Feel sick; Chronic cough abundant expectoration." book on Chinese herbal medicine is new again " carries: " control gas soothing liver-QI, stomach function regulating reduces phlegm, and removing mass controls dysphagia and regurgitation, eliminating mass abdominal mass scrofula." modern medicine study confirmation; Fructus Citri Sarcodactylis has phlegm-dispelling functions of relievining asthma; antagonism airway constriction; the tension force alleviating rapidly stomach, intestinal and gallbladder increases; extend convulsions time of origin, prevention arrhythmia, the resistance of increase strong wool blood vessel; reduce the ascorbic discharge of adrenal gland, also have the effect of antiinflammatory, antimicrobial acivity in addition.
Semen Oroxyli: mildly bitter flavor; Sweet; Cold nature.Sore-throat relieving lung moistening; Dispersing the stagnated liver-QI for regulating the stomach; Expelling pus and promoting granulation.Cure mainly pharyngalgia sore throat; Hoarseness; Cough; Stomachache due to hyperactive liver-QI attacking the stomach; Skin infection is burst for a long time and is not held back; Acute eczema." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " broken legendary venomous insect amasss, except the poison of tympanitis due to blood stasis, gas legendary venomous insect for Dingchuan, expectorant.Again can tonify deficiency, alleviating distention in middle-JIAO, feed." modern medicine study proves, Semen Oroxyli seed, seed coat, containing baicaligenin, have antiinflammatory, antiallergic action, diuresis, function of gallbladder promoting, the effect of cholesterol reducing, the chrysin contained in addition, have cytotoxic activity to human body nasopharyngeal carcinoma cell.
Fructus Aurantii Immaturus: bitter in the mouth; Pungent; Cold in nature.Enter spleen; Stomach; Liver; Heart channel.Dispelling the stagnated QI removing food stagnancy; Reduce phlegm except painful abdominal mass.Cure mainly in stagnating and stop; Feeling of fullness distending pain; Constipation; Heavy after dysentery; Blocked-up chest; Gastroptosis; Uterine prolapse; Proctoptosis." medicineization justice " carries: " Fructus Aurantii Immaturus specially lets out excess of the stomach, and convince hard knot by patient analysis, therefore the main middle part of gastric cavity is to control blood system, treat the interventral reality of umbilicus full, expectorant addiction, dispels and cut off the water, by dyspepsia, broken blocked-up chest, relieving constipation is closed, non-this can not be also.If skin pruritus, because of hematocele stagnant in, can not nutrition flesh table, if diet is not thought, because spleen pent-up can not transporting, all get power that its pungent loose hardship rushes down also.For the gas medicine in blood system, only this claims." Fructus Aurantii Immaturus can alleviate little enterospasm, increase gastrointestinal and shrink the rhythm and pace of moving things, impel gallbladder contraction, increase Oddi's sphincter tension force, inhibition thrombosis, particularly has antiulcer effect.
Calcucus Stomachi Bovis: lightly seasoned; Slightly warm in nature.GUIXIN; Stomach warp.Stopping nausea and vomiting by lowering the adverse flow of QI.Cure mainly dysphagia and regurgitation; Vomiting." Inner Mongol Chinese herbal medicine ": calm, stopping nausea and vomiting by lowering the adverse flow of QI.Control dysphagia and regurgitation, carsick, seasick vomiting.
Rhizoma Chuanxiong: acrid in the mouth; Warm in nature.Return liver; Gallbladder; Pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Zhu Zhi WEIJIA lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; Ulcer sores." book on Chinese herbal medicine just " carries: " dispersing wind and cold, control pain, removing blood stasis with potent drugs stores, promoting blood circulation, separates stagnation of QI, and by pain, evacuation of pus is subsided a swelling, and stimulates the menstrual flow by blood." modern medicine scientific research discovery; Rhizoma Chuanxiong extracting solution has certain effect to suppression leukaemia; preparation has certain antibacterial action; especially all have inhibitory action to Bacillus typhi, Salmonella paratyphi, vibrio cholera, bacillus pyocyaneus and pathogenic dermatophytes etc.; the ligustrazine contained by Rhizoma Chuanxiong, ferulic acid are received has blood circulation invigorating efficacies; expansible coronary artery, promote coronary flow, allevating angina pectoris, and there is anti-thrombosis function, contained cnidium lactone has smooth muscle spasmolysis and suppresses the effect such as myenteron, uterine contraction.
Fructus anethi: acrid in the mouth; Warm in nature.Return spleen; Stomach; Liver; Kidney channel.Warming the spleen whets the appetite; Cold expelling warms up liver; Regulating QI to relieve pain.Cure mainly cold type of pain in abdomen; Side of body rib distension; Vomiting lack of appetite; Colic of cold type." medical center bun is wanted ": the kidney invigorating of profit kidney, mend the gate of vitality, warm public region, appetizing above reaches Danzhong in adjusting, and soothing liver-QI wood reaches gloomy, relaxing muscles and tendons, lower to beriberi, controls colic of cold type.
Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have anti-gastric-ulcer, gastritis effect in addition.
Endothelium Corneum Gigeriae Galli: sweet in the mouth; Property is put down.Return spleen; Stomach; Kidney; Urinary bladder channel.Strengthening the spleen to promote digestion; Arresting seminal emission; Xiao Disorder fossil.Cure mainly dyspepsia; Eating accumulation; Vomiting regurgitation; To have loose bowels dysentery; Infantile malnutrition; Seminal emission; The enuresis; Frequent micturition; Urinary system calculus and cholelithiasis; Mass in the abdomen amenorrhea; Sore throat tonsillitis; Ulcerative gingivitis aphtha.Compendium of Material Medica is carried: " control children's's intermittent fever due to retention of food, treat dripping, the regurgitation of adult, the wine that disappears amasss, main inflammation of the throat, tonsillitis, all aphthas, all skin ulcers of ulcerative gingivitis." the clinical confirmation of modern medicine, Endothelium Corneum Gigeriae Galli is used for the treatment of the various diseases such as dyspepsia, chronic gastritis, cholelithiasis, cystitis, vesical calculus, oral ulcer, the seminal emission enuresis, gastric cancer, liver cirrhosis, has good curative effect.
Aspongopus: salty in the mouth; Warm in nature.Return through liver; Kidney; Spleen channel.Regulating QI to relieve pain, warming middle-JIAO is supporing yang.For cold syndrome of the stomach distending pain, stomachache due to hyperactive liver-QI attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint." detailed outline ": control diaphragm gastral cavity stagnant B1:B24 bacterium, Bacillus typhi, Salmonella paratyphi, shigella flexneri have stronger antibacterial action; And have promotion body metabolism.
The present invention compared with prior art, has following beneficial effect:
The present invention selects the property of medicine of medical material suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease such as depression of liver-QI, functional activity of QI being not smooth, horizontal criminal's taste causing caused by hepatic stagnation qi stagnation gastric retention, have in dispersing the stagnated liver-QI for regulating the stomach, invigorating the spleen and benefiting QI, warming the spleen appetizing, promoting digestion and removing stagnation, lower controlled atmosphere, effect of stopping nausea and vomiting by lowering the adverse flow of QI, regulating QI to relieve pain, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to caused by hepatic stagnation qi stagnation gastric retention cure rate through clinical verification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) Folium Microcoris paniculatae, Fructus Setariae Germinatus, Radix Ophiopogonis, Radix Rubi, the Rhizoma Atractylodis Macrocephalae, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Emmenopterys henryi oliv., Fructus Jujubae, wild Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus, Fructus Citri Sarcodactylis, Semen Oroxyli, Fructus anethi, Radix Glycyrrhizae are cleaned, dry rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Fructus Akebiae, Herba Paederiae are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(4) get Folium Eriobotryae cut tobacco, add cooked Mel and certain amount of boiling water, mix thoroughly, slightly vexed, put the interior slow fire of pot and fry to tack-free for spending, taking-up, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(5) first being removed by wheat bran in the even pot in heating, when marquis's cigarette is emerged, adding Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, and cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(6) be placed in pot by Calcucus Stomachi Bovis, slow fire heats, and constantly stir-fries, and take out time crisp to color burn quality, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(7) getting Rhizoma Chuanxiong sheet yellow wine sprays evenly, slightly vexed, and putting in pot and frying extremely micro-Jiao is degree, and taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(8) first sand is put into pot to make popular, then the Endothelium Corneum Gigeriae Galli cleaned is put into pot, stir and heave to brown color or coke yellow, take out with slow fire, sieve shakeout, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(9) getting clean Aspongopus puts in pot, and with slow fire heating, fry to when having fragrance to overflow, take out, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(10) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), step (9), add after refined honey stirs, be prepared as the pill of every 3g.
Usage and dosage: oral, each 2 of every day 3 times, one hour ante cibum, with warm water delivery service, 14 days was 1 course for the treatment of; Anemia of pregnant woman is cautious use of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
Select the routine clinical observation of caused by hepatic stagnation qi stagnation gastric retention patient 64 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random.Treatment group 32 example, wherein male 13 example, women 19 example, 19 ~ 73 years old age, 44.7 years old mean age, the shortest person of the course of disease 6 days, most elder 93 days, average 37 days.Matched group 32 example, wherein male 14 example, women 18 example, 17 ~ 75 years old age, 45.1 years old mean age, the shortest person of the course of disease 5 days, most elder 91 days, average 35 days.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, oral, each 2 of every day 3 times, and one hour ante cibum, with warm water delivery service, 14 days was 1 course for the treatment of, took 3 courses for the treatment of.Matched group patient is except carrying out general treatment as low-residue diet, and vitimin supplement and trace element and correct outside water, electrolyte and acid base imbalance, take promotion gastric motility medicine as required to the ill as metoclopramide, motilium etc. are treated.
3, efficacy determination:
(1) cure: the transference cures such as vomiting, abdominal distention, stomachache, gastrointestinal examination is normal.
(2) take a turn for the better: the symptoms such as vomiting, abdominal distention, stomachache obviously alleviate, and gastrointestinal examination obviously improves.
(3) invalid: symptom is with treating front no significant difference.
4, result
Cure 17 examples in treatment group, take a turn for the better 12 examples, invalid 3 examples, cure rate 53%, total effective rate 90.6%.
Cure 13 examples in matched group, take a turn for the better 14 examples, invalid 5 examples, cure rate 40.6%, total effective rate 84.4%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Lee's ××, man, 45 years old.This patient eats food one after the meeting, the sensation that existing food up returns, occasionally has vomiting with acid regurgitation, carrys out institute's inquiring, through clinical examination, be diagnosed as caused by hepatic stagnation qi stagnation gastric retention, after taking 1 course for the treatment of of Chinese medicine of the present invention, readme above-mentioned symptom obviously alleviates, follow the doctor's advice after continuing to take 1 course for the treatment of of Chinese medicine of the present invention, above-mentioned symptom disappears completely, and gastrointestinal examination is normal, fully recovers.
2, Cai's ××, female, 58 years old.Have vomiting with acid regurgitation, regurgitation, abdominal distention, unhappy symptom during patient, carry out institute's inquiring, through clinical examination, be diagnosed as caused by hepatic stagnation qi stagnation gastric retention, after taking 3 courses for the treatment of of Chinese medicine of the present invention, above-mentioned symptom disappears completely, and gastrointestinal examination is normal, fully recovers.
Gastric retention is a kind of common disease, studies discovery according to investigations, causes the reason of this kind of disease to have a lot, and dietary habit that is many and people is closely bound up.This disease is very large to the harm of people, and the sickness rate of gastric retention is higher, needs the treatment of long period.Adopt western medical treatment method, take metoclopramide, motilium etc. for a long time and promote gastric motility class medicine, can gastric hypokinesia be caused after drug withdrawal, easily produce drug dependence and drug resistance, certain side effect can be had to health simultaneously.Therefore adopt the traditional Chinese medical science to carry out dialectical treatment, regulate gastrointestinal function, facilitating digestion absorbs, and is the effective Therapeutic Method of one for the treatment of gastric retention.The present invention is through long-term clinical practice, according to the cause of disease of caused by hepatic stagnation qi stagnation gastric retention, suits the remedy to the case, and Fructus Akebiae, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Semen Oroxyli in side, Fructus Citri Sarcodactylis can dispersing the stagnated liver-QI for regulating the stomach; Radix Codonopsis in side, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae can invigorating the spleen and benefiting QI, harmonizing yingfen and weifen; Herba Paederiae in side, Folium Microcoris paniculatae, Radix Rubi, Endothelium Corneum Gigeriae Galli, Fructus Setariae Germinatus, wild Cortex Magnoliae Officinalis, Fructus Amomi Rotundus can spleen benefiting and stimulating the appetite, promoting digestion and removing stagnation; In side, Rhizoma Chuanxiong can blood circulation promoting and blood stasis dispelling; In side, Fructus Aurantii Immaturus can dispelling the stagnated QI removing food stagnancy; In side, Pericarpium Citri Reticulatae can descend in controlled atmosphere; Folium Eriobotryae in side, Emmenopterys henryi oliv., Calcucus Stomachi Bovis can stopping nausea and vomiting by lowering the adverse flow of QI; Fructus anethi in side, Aspongopus can warming the spleen appetizing, regulating QI to relieve pain; In side, Radix Ophiopogonis can YIN nourishing and the production of body fluid promoting; In side, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription; In side, all medicines share, can play in dispersing the stagnated liver-QI for regulating the stomach, invigorating the spleen and benefiting QI, warming the spleen appetizing, promoting digestion and removing stagnation, lower controlled atmosphere altogether, effect of stopping nausea and vomiting by lowering the adverse flow of QI, regulating QI to relieve pain, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to caused by hepatic stagnation qi stagnation gastric retention cure rate through clinical verification.

Claims (4)

1. be used for the treatment of a medicine pill for caused by hepatic stagnation qi stagnation gastric retention, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
2. a kind of medicine pill being used for the treatment of caused by hepatic stagnation qi stagnation gastric retention according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
3. a kind of medicine pill being used for the treatment of caused by hepatic stagnation qi stagnation gastric retention according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
4. be used for the treatment of a preparation method for the medicine pill of caused by hepatic stagnation qi stagnation gastric retention, it is characterized in that: comprise following processing step:
(1) Folium Microcoris paniculatae, Fructus Setariae Germinatus, Radix Ophiopogonis, Radix Rubi, the Rhizoma Atractylodis Macrocephalae, Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Emmenopterys henryi oliv., Fructus Jujubae, wild Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Fructus Amomi Rotundus, Fructus Citri Sarcodactylis, Semen Oroxyli, Fructus anethi, Radix Glycyrrhizae are cleaned, dry rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Fructus Akebiae, Herba Paederiae are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(4) get Folium Eriobotryae cut tobacco, add cooked Mel and certain amount of boiling water, mix thoroughly, slightly vexed, put the interior slow fire of pot and fry to tack-free for spending, taking-up, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(5) first being removed by wheat bran in the even pot in heating, when marquis's cigarette is emerged, adding Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, and cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(6) be placed in pot by Calcucus Stomachi Bovis, slow fire heats, and constantly stir-fries, and take out time crisp to color burn quality, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(7) getting Rhizoma Chuanxiong sheet yellow wine sprays evenly, slightly vexed, and putting in pot and frying extremely micro-Jiao is degree, and taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(8) first sand is put into pot to make popular, then the Endothelium Corneum Gigeriae Galli cleaned is put into pot, stir and heave to brown color or coke yellow, take out with slow fire, sieve shakeout, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(9) getting clean Aspongopus puts in pot, and with slow fire heating, fry to when having fragrance to overflow, take out, cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(10) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), step (9), add after refined honey stirs, be prepared as the pill of every 3g.
CN201510821823.5A 2015-11-24 2015-11-24 Traditional Chinese medicine pill used for treating liver-depression and qi-stagnation type gastric retention and preparation method thereof Withdrawn CN105288427A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822765A (en) * 2017-04-06 2017-06-13 孙晓风 A kind of instant particles as Chinese medicine and preparation method for stopping up stagnant disease for treating duodenum
CN107307156A (en) * 2017-08-23 2017-11-03 张可池 A kind of matrimony vine compound health life-prolonging tea

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周克振: "《中医类方妙用新编》", 30 June 2010, 湖南科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822765A (en) * 2017-04-06 2017-06-13 孙晓风 A kind of instant particles as Chinese medicine and preparation method for stopping up stagnant disease for treating duodenum
CN107307156A (en) * 2017-08-23 2017-11-03 张可池 A kind of matrimony vine compound health life-prolonging tea

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Application publication date: 20160203