CN113197793A - Blue light resistant composition and preparation method and application thereof - Google Patents

Blue light resistant composition and preparation method and application thereof Download PDF

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CN113197793A
CN113197793A CN202110403132.9A CN202110403132A CN113197793A CN 113197793 A CN113197793 A CN 113197793A CN 202110403132 A CN202110403132 A CN 202110403132A CN 113197793 A CN113197793 A CN 113197793A
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blue light
oil
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surfactant
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CN113197793B (en
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史学东
崔黎
杨深鹏
何纪添
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Guangzhou Deva Biological Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

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  • Life Sciences & Earth Sciences (AREA)
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  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the technical field of cosmetics, and discloses an anti-blue-light composition, and a preparation method and application thereof. The composition comprises the following components in percentage by mass: 0.1-10% of surfactant, 0.1-20% of polyalcohol and 0.1-5% of grease. The composition has strong blue light absorption capacity: the transmittance of the blue light wave band of 400 nm-500 nm is obviously lower than that of 500 nm-800 nm, the damage of the blue light to the skin can be prevented, the blue light protective effect is good, and the blue light resistant effect is excellent; meanwhile, the composition has no abnormality after being stored for 1 month in different environments (heat resistance at 45 ℃, cold resistance at-15 ℃, refrigeration at 5 ℃ and room temperature), and has good stability.

Description

Blue light resistant composition and preparation method and application thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to an anti-blue-light composition, and a preparation method and application thereof.
Background
Visible light is a part which can be perceived by human eyes in an electromagnetic spectrum, for example, white light is dispersed by a prism or a grating and then presents red, orange, yellow, green, blue, indigo and purple color bands, namely visible continuous spectrums, wherein the energy of a blue light wave band with the wavelength of 400-500 nm is the highest, and the visible continuous spectrums are called high-energy visible light. Blue light is not only present in sunlight and lighting lights, but also in a large amount in background light sources of digital products. With the continuous and intensive research, people find that blue light can not only damage the retina, but also has certain damage to the skin, including oxidative stress, pigmentation and the like, so that the influence of the blue light on the human body draws more and more attention, and people start to consciously carry out blue light protection research, such as blue light resistant cosmetics.
Blue light resisting technology applied in cosmetics protects skin mainly from the aspects of physically blocking, absorbing radiation, improving pigmentation, delaying skin aging and the like. The physical protection raw materials can directly block and reflect blue light, such as mica, pearl powder, boron nitride and other components which can refract and reflect visible light. Blue light absorbent such as lutein, coffee bean, etc. can reduce the transmittance of blue light by absorbing blue light, thereby achieving the blue light protection effect. The skin is excessively colored and deep by visible light, the color deep residue caused by blue light is more durable than that induced by UVB, and tyrosinase can be inhibited by using a photo-protective agent such as carotenoid and an antioxidant such as anthocyanin, flavone and tocopherol, so that the pigmentation caused by blue light radiation can be inhibited. The skin is excessively exposed to blue light to delay barrier repair, such as cacao seed extract, contains peptides, saccharides and polyphenols, has good antioxidant ability, and can significantly reduce mitochondrial active oxygen and cellular active oxygen induced by blue light pressure. However, the existing cosmetics have an unsatisfactory effect of protecting against blue light.
Disclosure of Invention
The object of the first aspect of the present invention is to provide a composition.
The object of the second aspect of the invention is to provide a process for the preparation of the composition of the first aspect of the invention.
The object of the third aspect of the present invention is to provide the use of the composition of the first aspect of the present invention for the preparation of a cosmetic product.
It is an object of a fourth aspect of the present invention to provide a cosmetic product comprising a composition according to the first aspect of the present invention.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
in a first aspect of the invention, a composition is provided, comprising the following components in percentage by mass: 0.1-10% of surfactant, 0.1-20% of polyalcohol and 0.1-5% of grease.
Preferably, the composition comprises the following components in percentage by mass: 0.5-6% of surfactant, 5-12.4% of polyalcohol and 0.1-4% of grease.
The surfactant is a surfactant with an HLB value of 9-20; preferably, the surfactant is a nonionic surfactant with an HLB value of 9-20; more preferably at least one of hydrogenated castor oil polyoxyethylene ether, polyoxyethylene ether sorbitan fatty acid ester, sucrose mono fatty acid ester and polyglycerol fatty acid ester; most preferably at least one of hydrogenated castor oil polyoxyethylene ether-20, hydrogenated castor oil polyoxyethylene ether-40, polyoxyethylene sorbitan trioleate, polyglycerol-4 laurate and polyglycerol-6 laurate.
Preferably, the polyhydric alcohol is at least one of glycerol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, methyl propylene glycol, diglycerol, triglycerol, and dipropylene glycol; further preferably, the polyhydric alcohol is at least one of glycerol, hexylene glycol and dipropylene glycol.
Preferably, the grease is at least one of silicone oil, hydrocarbon oil, ester oil and vegetable oil; more preferably, the oil and fat is at least one of ester oil and vegetable oil; still more preferably, the oil is at least one of rice bran oil, oat kernel oil, dioctyl carbonate and diisostearyl malate.
Preferably, the composition further comprises the following components in percentage by mass: 0-0.2% of astaxanthin; further preferably, the composition further comprises the following components in percentage by mass: 0-0.1% of astaxanthin; still further preferably, the composition further comprises the following components in percentage by mass: 0-0.01% of astaxanthin.
Preferably, the composition further comprises the following components in percentage by mass: 0.1 to 1 percent of preservative; further preferably, the composition further comprises the following components in percentage by mass: 0.36 to 0.5 percent of preservative.
Preferably, the composition further comprises the following components in percentage by mass: 0-10% of an organic solvent; further preferably, the composition further comprises the following components in percentage by mass: 0-9% of an organic solvent.
Preferably, the preservative is at least one of p-hydroxyacetophenone, phenoxyethanol and ethylhexyl glycerin.
Preferably, the organic solvent is ethanol.
Preferably, the composition further comprises water, the balance being water.
In a second aspect of the invention, there is provided a process for the preparation of the composition of the first aspect of the invention, said process being either scheme (a) or (B);
scheme (a):
(1) mixing a surfactant, grease and part of polyol, and then adding part of water to obtain a phase A;
(2) mixing the rest water, the rest polyalcohol and the preservative to obtain a phase B;
(3) mixing the phase A and the phase B to obtain a composition;
scheme (B):
(1) mixing astaxanthin with grease to obtain a mixed solution; then mixing the mixed solution with a surfactant and part of polyol, and finally adding part of water to obtain a phase A;
(2) mixing the rest water, the rest polyalcohol, the preservative and the organic solvent to obtain a phase B;
(3) mixing the phase A and the phase B to obtain the composition.
Preferably, the temperature of water in the step (1) in the scheme (A) is 30-50 ℃; further 35-45 ℃.
Preferably, the temperature of the phase B in the step (2) in the scheme (A) is 30-50 ℃; further 35-45 ℃.
Preferably, the temperature of the water in the step (1) in the scheme (B) is 30-50 ℃; further 35-45 ℃.
Preferably, the temperature of the phase A in the step (1) in the scheme (B) is 30-50 ℃; further 35-45 ℃.
Preferably, the temperature of the phase B in the step (2) in the scheme (B) is 30-50 ℃; further 35-45 ℃.
In a third aspect of the invention, there is provided the use of a composition according to the first aspect of the invention in the preparation of a cosmetic product.
In a fourth aspect of the invention, there is provided a cosmetic product comprising a composition according to the first aspect of the invention.
Preferably, the cosmetic further comprises an adjuvant.
Preferably, the adjuvant is at least one of a preservative, a chelating agent, a perfume, a humectant, a colorant, an antioxidant, and a skin conditioner.
Preferably, the cosmetic is at least one of a face wash, a lotion, an emulsion, a cream, and a essence.
The invention has the beneficial effects that:
the invention provides a composition, which has stronger blue light absorption capacity: the transmittance of the blue light wave band of 400 nm-500 nm is obviously lower than that of 500 nm-800 nm, the damage of the blue light to the skin can be prevented, the blue light protective effect is good, and the blue light resistant effect is excellent; meanwhile, the composition has no abnormality after being stored for 1 month in different environments (heat resistance at 45 ℃, cold resistance at-15 ℃, refrigeration at 5 ℃ and room temperature), and has good stability.
The blue light absorption capacity of the composition is further improved by adding astaxanthin: the transmittance of the blue light wave band of 400 nm-500 nm is more obviously lower than that of 500 nm-800 nm, and the blue light protective film has better blue light protection effect.
Drawings
FIG. 1 is a graph of the transmittance in the visible light band of composition 1 of example 1.
FIG. 2 is a graph of the transmittance in the visible light band of composition 2 of example 2.
FIG. 3 is a graph of the visible light band transmittance of composition 3 of example 3.
FIG. 4 is a graph of the visible band transmittance of composition 4 of example 4.
FIG. 5 is a graph of the visible light band transmittance of hydrogenated castor oil polyoxyethylene ether-40.
FIG. 6 is a graph showing the transmittance of hydrogenated castor oil polyoxyethylene ether-20 in the visible light range.
FIG. 7 is a graph showing the transmittance of polyoxyethylene sorbitan trioleate in the visible light band.
Fig. 8 is a graph of the visible light band transmittance for a surfactant solution with a mass fraction of 5% formulated from polyglycerol-4 laurate and polyglycerol-6 laurate.
FIG. 9 is a graph of the visible band transmittance of glycerol.
Fig. 10 is a graph of the visible band transmittance of dipropylene glycol.
FIG. 11 is a graph of the visible band transmittance of hexylene glycol.
FIG. 12 is a graph showing the transmittance of p-hydroxyacetophenone aqueous solution in the visible light band.
FIG. 13 is a graph of the visible band transmittance of ethanol.
FIG. 14 is a graph of the visible band transmittance of a mixture of phenoxyethanol and ethylhexylglycerin.
Fig. 15 is a graph of the visible band transmittance of olive oil.
FIG. 16 is a graph of the visible light band transmittance of wheat germ oil.
FIG. 17 is a graph of the transmittance of the seed oil of two sections of camelina sativa in the deep sea in the visible light band.
Fig. 18 is a graph of the visible band transmittance of golden jojoba oil.
Fig. 19 is a graph of the visible band transmittance of oat kernel oil.
FIG. 20 is a graph of the visible band transmittance of rice bran oil.
FIG. 21 is a graph of the transmittance of dioctyl carbonate in the visible light band.
FIG. 22 is a graph of the visible band transmittance of diisostearyl malate.
Fig. 23 is a graph of the visible band transmittance of a mixture of hydrogenated olive oil ethylhexyl oleate and hydrogenated olive oil unsaponifiables.
FIG. 24 is a graph showing the transmittance in the visible light band of a diisostearyl malate solution containing 1% by mass of astaxanthin.
Detailed Description
The present invention will be described in further detail with reference to specific examples.
It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
The experimental procedures, in which specific conditions are not noted in the following examples, are generally carried out under conventional conditions or conditions recommended by the manufacturers. The materials, reagents and the like used in the present examples are commercially available reagents and materials unless otherwise specified.
Example 1A composition
A composition, the components of which are shown in Table 1, is prepared by the following method:
(1) heating part of water (20% by mass) to 80-85 ℃, preserving heat for 20 minutes, sterilizing, and then cooling to 40 ℃;
(2) mixing hydrogenated castor oil polyoxyethylene ether-20, rice bran oil and glycerol, uniformly stirring, slowly adding the water obtained in the step (1) while stirring, and continuously stirring for 5 minutes after the water is added to obtain a phase A;
(3) mixing the rest water, 1, 2-hexanediol and p-hydroxyacetophenone, heating to 80-85 ℃ while stirring, preserving heat for 20 minutes for disinfection, and then cooling to 40 ℃ to obtain a phase B;
(4) add phase A to phase B and stir for 5 minutes to give the composition.
TABLE 1 formulation of the composition of example 1
Number of component Component name Mass percent (%)
1 Hydrogenated castor oil polyoxyethylene ether-20 6
2 Rice bran oil 4
3 Glycerol 12
4 Water (W) To 100 of
5 1, 2-hexanediol 0.4
6 P-hydroxyacetophenone 0.5
Example 2A composition
A composition, the components of which are shown in Table 2, is prepared by the following steps:
(1) heating part of water (20% by mass) to 80-85 ℃, preserving heat for 20 minutes, sterilizing, and then cooling to 40 ℃;
(2) mixing hydrogenated castor oil polyoxyethylene ether-40, polyoxyethylene sorbitan trioleate, oat kernel oil and dipropylene glycol, uniformly stirring, slowly adding the water obtained in the step (1) while stirring, and continuously stirring for 5 minutes after the water is added to obtain a phase A;
(3) mixing the rest water, phenoxyethanol and ethylhexyl glycerol, heating to 80-85 ℃ while stirring, preserving heat for 20 minutes for disinfection, and then cooling to 40 ℃ to obtain a phase B;
(4) add phase A to phase B and stir for 5 minutes to give the composition.
TABLE 2 formulation of the composition of example 2
Number of component Component name Mass percent%
1 Polyoxyethylene sorbitan trioleate 0.2
2 Hydrogenated castor oil polyoxyethylene ether-40 0.3
3 Oat kernel oil 0.1
4 Double propylGlycol 5
5 Water (W) To 100 of
6 Phenoxyethanol 0.36
7 Ethyl hexyl glycerol 0.04
Example 3A composition
A composition having the components shown in Table 3 was prepared as follows:
(1) heating part of water (20% by mass) to 80-85 ℃, preserving heat for 20 minutes, sterilizing, and then cooling to 40 ℃;
(2) mixing polyglycerol-4 laurate, polyglycerol-6 laurate, dioctyl carbonate and 1, 2-hexanediol, heating to 80-85 ℃, preserving heat for 20 minutes, sterilizing, slowly adding the water in the step (1), and continuously stirring for 5 minutes after adding to obtain a phase A;
(3) heating the rest water, glycerol and p-hydroxyacetophenone to 80-85 ℃, preserving heat for 20 minutes, cooling to 40 ℃, adding the phase A, and stirring for 5 minutes to obtain the composition.
TABLE 3 formulation of the composition of example 3
Number of component Component name Mass percent%
1 Polyglycerol-4 laurate 3
2 Polyglycerol-6 laurate 2
3 Carbonic acid dioctyl ester 1
4 1, 2-hexanediol 0.4
5 P-hydroxyacetophenone 0.5
6 Glycerol 5
7 Water (W) To 100 of
Example 4A composition
A composition having the components shown in Table 4 was prepared as follows:
(1) heating part of water (20% by mass) to 80-85 ℃, preserving heat for 20 minutes, sterilizing, and then cooling to 40 ℃;
(2) mixing astaxanthin and diisostearyl malate, heating to 50-60 ℃, stirring and dissolving uniformly, then adding hydrogenated castor oil polyoxyethylene ether-20 and 1.5% glycerol, mixing, stirring and cooling to 40 ℃, then slowly adding the water in the step (1) while stirring, and continuing to stir for 5 minutes after the water is added to obtain a phase A;
(3) heating the rest water to 80-85 ℃, preserving heat for 20 minutes for disinfection, then cooling to 40 ℃, and then mixing and stirring with the rest glycerol, ethylhexyl glycerol, phenoxyethanol and 95% ethanol to obtain a phase B;
(4) add phase A to phase B and stir for 5 minutes to give the composition.
TABLE 4 compounding ratio of the composition of example 4
Number of component Component name Mass percent%
1 Astaxanthin 0.01
2 Diisostearyl malate 0.99
3 Hydrogenated castor oil polyoxyethylene ether-20 0.75
4 Glycerol 1.5
5 Water (W) To 100 of
6 Glycerol 5
7 Phenoxyethanol 0.36
8 Ethyl hexyl glycerol 0.04
9 95% ethanol (v/v) 9
Effects of the embodiment
1. Anti-blue light test
The light transmittance of the compositions 1 to 4 prepared in examples 1 to 4 in the visible light band of 400nm to 800nm was measured by using an ultraviolet-visible spectrophotometer, and the results are shown in fig. 1 to 4: FIG. 1 shows: the transmittance of the composition 1 in a blue light wave band of 400 nm-500 nm is obviously lower than that in a visible light wave band of 500 nm-800 nm, so that the composition 1 has a good blue light absorption effect and a good blue light protection effect: in the composition 1, only the rice bran oil can absorb blue light, the transmittance in a blue light wave band of 400 nm-500 nm is 15% -85%, while the transmittance in the blue light wave band of 400 nm-500 nm of the composition 1 is only about 12% -48%, which is obviously lower than that of the rice bran oil, and the transmittance of other components is close to 100%, thus the composition of the embodiment has unexpected technical effect; FIG. 2 shows: the transmittance of the composition 2 in a 400 nm-500 nm blue light wave band is lower than 25%, and is obviously lower than a 500 nm-800 nm visible light wave band, so that the composition 2 has a good blue light absorption effect and a good blue light protection effect; FIG. 3 shows: the transmittance of the composition 3 in a blue light wave band of 400 nm-500 nm is lower than 30%, and is obviously lower than a visible light wave band of 500 nm-800 nm, so that the composition 3 has a good blue light absorption effect and a good blue light protection effect: in the composition 3, only the mixture of the polyglycerol-4 laurate and the polyglycerol-6 laurate can absorb blue light, the transmittance in a blue light wave band of 400 nm-500 nm is 17% -44%, while the transmittance in a blue light wave band of 400 nm-500 nm of the composition 3 is only about 5% -22%, which is significantly lower than the transmittance of the mixture of the polyglycerol-4 laurate and the polyglycerol-6 laurate, and the transmittance of other components is close to 100%, and the composition of the embodiment has unexpected technical effects; FIG. 4 shows: the transmittance of the composition 4 in a blue light wave band of 400 nm-500 nm is lower than 10%, and is obviously lower than that in a visible light wave band of 500 nm-800 nm, so that the composition 4 has a good blue light absorption effect and a good blue light protection effect.
2. Stability test
The compositions 1 to 4 prepared in examples 1 to 4 were respectively stored at 45 ℃ for 1 month, at-15 ℃ for 1 month, at 5 ℃ for 1 month and at room temperature (25 to 30 ℃) for 1 month, and the results are shown in Table 5: the compositions 1 to 4 prepared in examples 1 to 4 had good stability.
TABLE 5 stability of compositions 1-4 prepared in examples 1-4
Experimental project Composition 1 Composition 3 Composition 3 Composition 4
Heat resistance at 45 deg.C for 1 month Recovery from room temperature without abnormality Recovery from room temperature without abnormality Recovery from room temperature without abnormality Recovery from room temperature without abnormality
Cold resistance at-15 deg.C for 1 month Recovery from room temperature without abnormality Recovery from room temperature without abnormality Recovery from room temperature without abnormality Recovery from room temperature without abnormality
Refrigerating at 5 deg.C for 1 month Recovery from room temperature without abnormality Recovery from room temperature without abnormality Recovery from room temperature without abnormality Recovery from room temperature without abnormality
Room temperature 1 month No abnormal at room temperature No abnormal at room temperature No abnormal at room temperature No abnormal at room temperature
Comparative example
1. Anti-blue light effect of surfactants
Respectively taking hydrogenated castor oil polyoxyethylene ether-40, hydrogenated castor oil polyoxyethylene ether-20, polyoxyethylene sorbitan trioleate and a surfactant solution which is prepared from polyglycerol-4 laurate and polyglycerol-6 laurate and has the mass fraction of 5% (wherein the mass fraction of the polyglycerol-4 laurate is 3%, and the mass fraction of the polyglycerol-6 laurate is 2%), measuring the light transmittance of the components in a visible light waveband of 400-800 nm by using an ultraviolet-visible spectrophotometer, and obtaining the results as shown in figures 5-8: FIG. 5 shows: the transmittance of the hydrogenated castor oil polyoxyethylene ether-40 in a blue light wave band of 400 nm-500 nm is close to 100 percent, and the hydrogenated castor oil polyoxyethylene ether-40 has no blue light absorption effect, namely no blue light protection effect; FIG. 6 shows: the transmittance of the hydrogenated castor oil polyoxyethylene ether-20 in a blue light wave band of 400 nm-500 nm is more than 90%, and the blue light absorption effect of the hydrogenated castor oil polyoxyethylene ether-20 is weak, namely the blue light protection effect can be ignored; fig. 7 and 8 show: the transmittance of a surfactant solution with 5% by mass, which is prepared from polyoxyethylene sorbitan trioleate and polyglycerol-4 laurate and polyglycerol-6 laurate, in a 400 nm-500 nm blue light wave band is obviously lower than that of a 500 nm-800 nm visible light wave band, so that the surfactant solution has a blue light absorption effect, namely a blue light protection effect.
2. Anti-blue light effect of polyhydric alcohol, p-hydroxyacetophenone, ethanol, phenoxyethanol and ethylhexylglycerin
The method comprises the following steps of (1) respectively taking glycerol, dipropylene glycol, hexanediol, 0.5% (mass fraction) of p-hydroxyacetophenone aqueous solution, 95% (v/v) of ethanol, and a mixture of phenoxyethanol and ethylhexyl glycerol (the mass ratio of phenoxyethanol to ethylhexyl glycerol is 90:10), and measuring the light transmittance of the components in a visible light band of 400-800 nm by using an ultraviolet-visible spectrophotometer, wherein the results are shown in fig. 9-14: fig. 9, fig. 10, fig. 11, fig. 12, fig. 13, fig. 14 show: the transmittance of the mixture of glycerol, dipropylene glycol, hexanediol, 0.5% (mass fraction) p-hydroxyacetophenone aqueous solution, 95% (v/v) ethanol, phenoxyethanol and ethylhexyl glycerol is close to 100% in a blue light wave band of 400-500 nm, and the mixture of glycerol, dipropylene glycol, hexanediol, 0.5% (mass fraction) p-hydroxyacetophenone aqueous solution, 95% (v/v) ethanol, phenoxyethanol and ethylhexyl glycerol has no blue light absorption effect, namely no blue light protection effect.
3. Anti-blue light effect of grease
Respectively taking olive oil, wheat germ oil, crambe abyssinica seed oil, golden yellow jojoba oil, oat kernel oil, rice bran oil, dioctyl carbonate, diisostearyl malate, hydrogenated ethylhexyl olive oleate and a mixture of hydrogenated olive oil unsaponifiable substances (the mass ratio of the hydrogenated ethylhexyl olive oleate to the hydrogenated olive oil unsaponifiable substances is 97: 3), and measuring the light transmittance of the components in a visible light band of 400-800 nm by using an ultraviolet-visible spectrophotometer, wherein the results are shown in fig. 15-23: fig. 21, 22, 23 show: the transmittance of the mixture of the dioctyl carbonate, the diisostearyl malate, the hydrogenated olive oil ethylhexyl oleate and the hydrogenated olive oil unsaponifiable matter in the blue light wave band of 400-500 nm is close to 100 percent, and the mixture of the dioctyl carbonate, the diisostearyl malate, the hydrogenated olive oil ethylhexyl oleate and the hydrogenated olive oil unsaponifiable matter has no blue light absorption, namely no blue light protection effect; fig. 15, 17, 18, 20 show: the transmittances of olive oil, crambe abyssinica seed oil, golden yellow jojoba oil and rice bran oil in a blue light wave band of 400 nm-500 nm are obviously lower than those in a visible light wave band of 500 nm-800 nm, and fig. 16 shows that: the blue light wave band of the wheat germ oil with the wavelength of 400 nm-500 nm is also lower than most of the visible light wave band of 500 nm-800 nm, and the blue light absorption of the olive oil, the wheat germ oil, the crambe seed oil in deep sea, the golden yellow jojoba oil, the rice bran oil and the wheat germ oil can be seen, namely the blue light protection effect is achieved; FIG. 19 shows: the transmissivity of the oat kernel oil is close to 0 in a blue light wave band of 400-500 nm, so that the oat kernel oil has complete blue light absorption effect, namely excellent blue light protection effect.
4. Blue light resistance of astaxanthin
Diluting astaxanthin by using oil diisostearyl malate to obtain astaxanthin with the concentration of 1% (mass fraction), wherein the transmittance of the diisostearyl malate in a blue light wave band of 400-500 nm is close to 100%, and the blue light absorption effect of the astaxanthin is not influenced; the light transmittance of the above components in the visible light band of 400nm to 800nm was measured using an ultraviolet-visible spectrophotometer, and the results are shown in fig. 24: the transmittance of 1% of astaxanthin in a blue light wave band of 400 nm-500 nm is close to 0, and the astaxanthin can be considered to have complete blue light absorption, namely, an excellent blue light protection effect.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims (10)

1. A composition comprising the following components in percent by mass: 0.1-10% of surfactant, 0.1-20% of polyalcohol and 0.1-5% of grease.
2. The composition of claim 1, wherein:
the surfactant is a surfactant with an HLB value of 9-20; preferably, the surfactant is a nonionic surfactant with an HLB value of 9-20; more preferably at least one of hydrogenated castor oil polyoxyethylene ether, polyoxyethylene ether sorbitan fatty acid ester, sucrose mono fatty acid ester and polyglycerol fatty acid ester; most preferably at least one of hydrogenated castor oil polyoxyethylene ether-20, hydrogenated castor oil polyoxyethylene ether-40, polyoxyethylene sorbitan trioleate, polyglycerol-4 laurate and polyglycerol-6 laurate.
3. The composition of claim 2, wherein:
the polyalcohol is at least one of glycerol, propylene glycol, butanediol, pentanediol, hexanediol, methyl propylene glycol, diglycerol, triglycerol and dipropylene glycol;
preferably at least one of glycerol, hexylene glycol and dipropylene glycol.
4. The composition of claim 3, wherein:
the grease is at least one of silicone oil, hydrocarbon oil, ester oil and vegetable oil; preferably at least one of an ester oil and a vegetable oil; more preferably at least one of rice bran oil, oat kernel oil, dioctyl carbonate, and diisostearyl malate.
5. The composition according to any one of claims 1 to 4, characterized in that:
the composition also comprises the following components in percentage by mass: 0.1 to 1 percent of preservative.
6. The composition of claim 5, wherein: the composition also comprises the following components in percentage by mass: 0-10% of an organic solvent;
preferably, the composition further comprises the following components in percentage by mass: 0-0.2% of astaxanthin.
7. A method of preparing the composition of claim 5, comprising the steps of:
(1) mixing a surfactant, grease and part of polyol, and then adding part of water to obtain a phase A;
(2) mixing the rest water, the rest polyalcohol and the preservative to obtain a phase B;
(3) mixing the phase A and the phase B to obtain the composition.
8. A method of preparing the composition of claim 6, comprising the steps of:
(1) mixing astaxanthin with grease to obtain a mixed solution; then mixing the mixed solution with a surfactant and part of polyol, and finally adding part of water to obtain a phase A;
(2) mixing the rest water, the rest polyalcohol, the preservative and the organic solvent to obtain a phase B;
(3) mixing the phase A and the phase B to obtain the composition.
9. Use of a composition according to any one of claims 1 to 6 for the preparation of a cosmetic product.
10. A cosmetic comprising the composition of any one of claims 1 to 6.
CN202110403132.9A 2021-04-15 2021-04-15 Blue light resistant composition and preparation method and application thereof Active CN113197793B (en)

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