CN103445989A - Sun-proof skin care composition and preparation method thereof - Google Patents
Sun-proof skin care composition and preparation method thereof Download PDFInfo
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- CN103445989A CN103445989A CN201310336465XA CN201310336465A CN103445989A CN 103445989 A CN103445989 A CN 103445989A CN 201310336465X A CN201310336465X A CN 201310336465XA CN 201310336465 A CN201310336465 A CN 201310336465A CN 103445989 A CN103445989 A CN 103445989A
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Abstract
The invention provides a sun-proof skin care composition and a preparation method thereof. The composition comprises main raw materials including millet bran oil, oryzanol, procyanidolic oligomer, silicon dioxide, titanium dioxide and the like. The preparation method comprises the following steps: taking liquid paraffin, distill monoglyceride, the millet bran oil and the oryzanol as a phase A; taking the procyanidolic oligomer, polyglycerol fatty acid ester, sucrose fatty acid ester, glycerol and deionized water as a phase B, and the silicon dioxide and the titanium dioxide as a phase C; taking ethylparaben and essence as a phase D; respectively heating and dissolving the phase A and the phase B, so that the temperature achieves 60-75 DEG C; slowly adding the phase B and the phase C to the phase A under a mixing condition respectively; carrying out vacuum nitrogen charge treatment on the system, and adding the phase D when emulsion is cooled to about 45-55 DEG C; and evenly emulsifying and cooling to room temperature. The emulsion prepared from the sun-proof skin care composition can play a role of absorbing or shielding different bands of ultraviolet rays.
Description
Technical field
The present invention relates to cosmetics, be specifically related to a kind of sun-proof skin care composition and method of making the same that contains the Semen setariae rice oil.
Technical background
The Semen setariae rice oil is to extract the Vegetable oil lipoprotein obtained from the Semen setariae bran coat, contains the several functions compositions such as linoleic acid, linolenic acid, plant sterol, oryzanol, Squalene, vitamin E in the Testa oryzae oils and fats, and wherein oryzanol content is up to 2-2.7%.
Existing about prepare the research of emulsion with Vegetable oil lipoprotein; as utilizing Fructus Maydis oil to prepare nanoemulsions, patent 201110087892.X obtains the little transparent emulsion of particle diameter; but they just have the emulsion of the effects such as regulation of skin secretion, skin protection not by the sun-proof first step that is used as protecting skin.In patent 200710030786.1, a kind of sunscreen cream of preparation, used multiple sun-prevention component sun-proof result better, but mostly be chemical sunscreen, skin had to certain zest, particularly to drying type skin.At present, the existing research of Semen setariae rice oil aspect blood fat reducing and antioxidation, but it is not yet reported in the research aspect the sun-proof skin care beauty treatment.Therefore, based on the Semen setariae rice oil, itself be rich in oryzanol and other active component, the present invention is intended to develop a kind of Semen setariae rice oil sun-proof skin care cosmetics according to the characteristics of Semen setariae rice oil.
Summary of the invention
The object of the present invention is to provide a kind of sun-proof skin care composition and method of making the same.This preparation method is simple, and the compositions obtained has sun-proof result, and the energy nourishes rough skin, have no stimulation to skin.
A kind of sun-proof skin care compositions provided by the invention, contain the Semen setariae rice oil, its components based on weight percentage: liquid paraffin 1-2%, Semen setariae rice oil 3-10%, oryzanol 0.5-2%, Oligomeric Proanthocyanidins 0.01-0.2%, molecule distillating monoglyceride 0.4-2%, polyglyceryl fatty acid ester 0.5-2%, sucrose fatty acid ester 0.5-2%, glycerol 2-10%, silicon dioxide and titanium dioxide 0.6-2%, ethyl hydroxybenzoate 0.05-0.1%, essence 0.2-0.8%, surplus is deionized water.The weight ratio of described silicon dioxide and titanium dioxide is 1:1～5.
The preparation method of a kind of sun-proof skin care compositions provided by the invention, step comprises:
(1) liquid paraffin, molecule distillating monoglyceride, Semen setariae rice oil and oryzanol are mixed to get to the A phase;
(2) Oligomeric Proanthocyanidins, polyglyceryl fatty acid ester, sucrose fatty acid ester, glycerol and deionized water are mixed to get to the B phase; Silicon dioxide mixes as C phase with titanium dioxide; Ethyl hydroxybenzoate and essence are as the D phase;
(3) by A phase, B mutually respectively heating for dissolving make its temperature all reach 60-75 ℃; Under stirring condition, successively B phase, C are joined mutually slowly A mutually in; Emulsification system is carried out to the evacuation processing, filled nitrogen and process when vacuum is 0.05-0.08MPa, the oxygen content in emulsification system is reached below 1%.Stir filling under the nitrogen condition, emulsion adds the D phase while being cooled to 45-55 ℃, is cooled to room temperature after emulsifying evenly and gets final product.
Compared with prior art, the present invention has following advantage and effect:
1. the present invention, when the preparation compositions, has added oryzanol, and purpose is the content that increases oryzanol in emulsion, utilizes its characteristics stronger to ultra-violet absorption at 280-320nm, strengthens the sun-proof result of said composition.After oryzanol adds in oil, can strengthen the ultra-violet absorption effect that there is oryzanol in Semen setariae rice oil Central Plains, thereby strengthen the sun-proof skin care effect of this emulsion, also can reduce the zest of chemosynthesis sunscreen to skin.This sunlight screening skin-protecting product can play and absorb or the ultraviolet effect of shielding different-waveband.
2. add Oligomeric Proanthocyanidins in compositions of the present invention, can be used as the protective agent of oryzanol, also can protect vitamin E, Squalene isoreactivity composition in the Semen setariae rice oil.Oligomeric Proanthocyanidins skin is non-stimulated, and skin is had to the anti-oxidation protection effect, can improve the skin protection anti-sunlight function of this emulsion.
3. the present invention is when carrying out emulsifying; adopt vacuum and filled the technology that nitrogen is combined with; when emulsification system vacuum reaches 0.05-0.08MPa; being filled nitrogen processes again; so not only avoid the boiling of emulsification system and foaming phenomenon but also can be down to the oxygen content in emulsification system minimumly, can protect to greatest extent the not oxidated destruction of active component of emulsion.
The specific embodiment
Embodiment 1
Compositions proportioning: liquid paraffin 1g, Semen setariae rice oil 9g, oryzanol 2g, Oligomeric Proanthocyanidins 0.2g, molecule distillating monoglyceride 1g, polyglyceryl fatty acid ester 1.5g, sucrose fatty acid ester 1.8g, glycerol 8g, silicon dioxide 0.4g, titanium dioxide 0.8g, ethyl hydroxybenzoate 0.1g, essence 0.8g, deionized water 73.4g.
The compositions preparation:
Liquid paraffin, molecule distillating monoglyceride, Semen setariae rice oil and oryzanol are mixed to get to the A phase; Oligomeric Proanthocyanidins, polyglyceryl fatty acid ester, sucrose fatty acid ester, glycerol and deionized water are mixed to get to the B phase; Silicon dioxide mixes as C phase with titanium dioxide; Ethyl hydroxybenzoate and essence are as the D phase; By A phase, B mutually respectively heating for dissolving make its temperature reach 65 ℃; Under stirring condition, successively B phase, C are joined mutually slowly A mutually in; Emulsification system is carried out to the evacuation processing, filled nitrogen and processed when vacuum is 0.08MPa, after vacuum-fill nitrogen cycle operation 3 times, stirred filling under the nitrogen condition, emulsion adds the D phase while being cooled to 50 ℃ of left and right, obtain Semen setariae rice oil sun-proof skin care compositions after being cooled to room temperature after emulsifying evenly.
This emulsion is smeared to back depilation mice, and applying amount is 0.2ml/ .d, and application area is about 2cm * 2cm.After smearing, mice is placed under artificial uviol lamp and irradiates, every day 1-2h, the Mus box is apart from UV light source 40cm, Continuous irradiation stops in 13 weeks.Wherein UVA exposure rate accumulative total is 304.5J/cm
2, UVB exposure rate accumulative total is 6.3J/cm
2.After off-test, measure the indexs such as malonaldehyde (MDA), peroxidase (CAT) and hydroxyproline (HYP) in mouse skin.Result shows, Semen setariae rice oil sun-proof skin care compositions is smeared the MDA content of group mouse skin, the CAT vigor, and HYP content, the indicator and model groups such as skin quality compare that there were significant differences (P<0.05 or P<0.01).Data are in Table 1.
Table 1 is respectively organized skin quality, MDA content, CAT vigor and the HYP content (n=10, X ± S) of mouse skin
Annotate: with model group, compare,
*p<0.05,
*p<0.01.
Embodiment 2
Compositions proportioning: liquid paraffin 2g, Semen setariae rice oil 4g, oryzanol 1g, Oligomeric Proanthocyanidins 0.1g, molecule distillating monoglyceride 0.5g, polyglyceryl fatty acid ester 0.8g, sucrose fatty acid ester 1.1g, glycerol 5g, silicon dioxide 0.5g, titanium dioxide 0.6g, ethyl hydroxybenzoate 0.05g, essence 0.4g, deionized water 83.95g.
The compositions preparation:
Liquid paraffin, molecule distillating monoglyceride, Semen setariae rice oil and oryzanol are mixed to get to the A phase; Oligomeric Proanthocyanidins, polyglyceryl fatty acid ester, sucrose fatty acid ester, glycerol and deionized water are mixed to get to the B phase; Silicon dioxide mixes as C phase with titanium dioxide; Ethyl hydroxybenzoate and essence are as the D phase; By A phase, B mutually respectively heating for dissolving make its temperature reach 60 ℃; Under stirring condition, by B phase, C join slowly mutually A mutually in; Emulsification system is carried out to the evacuation processing, filled nitrogen and processed when vacuum is 0.06MPa, after vacuum-fill nitrogen cycle operation 4 times, stirred filling under the nitrogen condition, emulsion adds the D phase while being cooled to 45 ℃ of left and right, obtain Semen setariae bran coat oil sun-proof skin care compositions after being cooled to room temperature after emulsifying evenly.
This emulsion is pressed 0.25ml/ .d applying amount mice depilation back, smear with uviol lamp under illuminate condition with embodiment 1, Continuous irradiation termination in 13 weeks.UVA exposure rate accumulative total is 304.5J/cm
2, UVB exposure rate accumulative total is 6.3J/cm
2.After off-test, measure the indexs such as MDA, CAT, HYP in the skin in mouse skin.Result shows, Semen setariae rice oil sun-proof skin care composition emulsion is smeared the MDA content of mouse skin group, the CAT vigor, and HYP content, the indicator and model groups such as skin quality compare that there were significant differences (P<0.05 or P<0.01).Data are in Table 2.
Table 2 is respectively organized skin quality, MDA content, CAT vigor and the HYP content (n=10, X ± S) of mouse skin
Annotate: with model group, compare,
*p<0.05,
*p<0.01.
Embodiment 3
Compositions proportioning: liquid paraffin 1.5g, Semen setariae rice oil 6g, oryzanol 1.5g, Oligomeric Proanthocyanidins 0.15g, molecule distillating monoglyceride 0.8g, polyglyceryl fatty acid ester 1.2g, sucrose fatty acid ester 1.3g, glycerol 3g, silicon dioxide 0.3g, titanium dioxide 0.7g, ethyl hydroxybenzoate 0.08g, essence 0.6g, deionized water 82.87g.
The compositions preparation:
Liquid paraffin, molecule distillating monoglyceride, Semen setariae rice oil and oryzanol are mixed to get to the A phase; Oligomeric Proanthocyanidins, polyglyceryl fatty acid ester, sucrose fatty acid ester, glycerol and deionized water are mixed to get to the B phase; Silicon dioxide mixes as C phase with titanium dioxide; Ethyl hydroxybenzoate and essence are as the D phase; By A phase, B mutually respectively heating for dissolving make its temperature reach 70 ℃; Under stirring condition, by B phase, C join slowly mutually A mutually in; Emulsification system is carried out to the evacuation processing, filled nitrogen and processed when vacuum is 0.075MPa, after vacuum-fill nitrogen cycle operation 3 times, stirred filling under the nitrogen condition, emulsion adds the D phase while being cooled to 55 ℃ of left and right, obtain Semen setariae rice oil sun-proof skin care compositions after being cooled to room temperature after emulsifying evenly.
Select 15 without dermopathic healthy women volunteer, this emulsion to be applied on its arm, smear continuously one month.This emulsion has the sensation of salubrious exquisiteness.Smear rear dermal sensation nature, comfortable, but large tracts of land is smeared.The place that this emulsion is not smeared in the place that volunteer's arm is smeared this emulsion seems more fine and smooth, flexible and occurs without keratinization and erythema.
Claims (3)
1. a sun-proof skin care compositions, is characterized in that, contains the Semen setariae rice oil.
2. a sun-proof skin care compositions, is characterized in that, its components based on weight percentage: liquid paraffin 1-2%, Semen setariae rice oil 3-10%, oryzanol 0.5-2%, Oligomeric Proanthocyanidins 0.01-0.2%, molecule distillating monoglyceride 0.4-2%, polyglyceryl fatty acid ester 0.5-2%, sucrose fatty acid ester 0.5-2%, glycerol 2-10%, silicon dioxide and titanium dioxide 0.6-2%, ethyl hydroxybenzoate 0.05-0.1%, essence 0.2-0.8%, surplus is deionized water.The weight ratio of described silicon dioxide and titanium dioxide is 1:1～5.
3. the preparation method of a kind of sun-proof skin care compositions as claimed in claim 2, is characterized in that, step comprises:
(1) liquid paraffin, molecule distillating monoglyceride, Semen setariae rice oil and oryzanol are mixed to get to the A phase;
(2) Oligomeric Proanthocyanidins, polyglyceryl fatty acid ester, sucrose fatty acid ester, glycerol and deionized water are mixed to get to the B phase; Silicon dioxide mixes as C phase with titanium dioxide; Ethyl hydroxybenzoate and essence are as the D phase;
(3) by A phase, B mutually respectively heating for dissolving make its temperature all reach 60-75 ℃; Under stirring condition, successively B phase, C are joined mutually slowly A mutually in; Emulsification system is carried out to the evacuation processing, filled nitrogen and process when vacuum is 0.05-0.08MPa, the oxygen content in emulsification system is reached below 1%.Stir filling under the nitrogen condition, emulsion adds the D phase while being cooled to 45-55 ℃, is cooled to room temperature after emulsifying evenly and gets final product.
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816073A (en) * | 2014-02-19 | 2014-05-28 | 邹琳 | Oligomeric proanthocyanidins chest-enlarging breast maintenance massage agent |
| CN103830148A (en) * | 2014-03-20 | 2014-06-04 | 宁波保税区攀峒信息科技有限公司 | Grain oil and Chinese yam skin-care paste and processing method |
| CN103830146A (en) * | 2014-03-20 | 2014-06-04 | 宁波保税区攀峒信息科技有限公司 | Grain oil and pumpkin skin care cream and processing method thereof |
| CN103860433A (en) * | 2014-03-20 | 2014-06-18 | 宁波保税区攀峒信息科技有限公司 | Cereal oil and sweet potato skin care cream and processing method |
| CN105113263A (en) * | 2014-05-14 | 2015-12-02 | 青岛蓝农谷农产品研究开发有限公司 | Antibacterial fiber dipping composition |
| CN106176460A (en) * | 2016-08-30 | 2016-12-07 | 陈燕兰 | A kind of skin care compositions with sun-proof function and preparation method and application |
| CN108042377A (en) * | 2017-12-28 | 2018-05-18 | 广州蜜妆生物科技有限公司 | One kind is planted extraction physical protection breast and preparation method thereof |
| CN108904337A (en) * | 2018-09-21 | 2018-11-30 | 河南中医药大学 | It is a kind of using crude vegetal as the lipstick of raw material |
| CN109172451A (en) * | 2018-10-23 | 2019-01-11 | 天津大学 | A kind of skin-whitening suncream and preparation method thereof |
| CN113197793A (en) * | 2021-04-15 | 2021-08-03 | 广州天玺生物科技有限公司 | Blue light resistant composition and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744145A (en) * | 1994-11-05 | 1998-04-28 | Nestec S.A. | Preparation of lipid compositions for cosmetic products |
| US20080233060A1 (en) * | 2007-03-19 | 2008-09-25 | Grune Guerry L | High SPF transparent or translucent, cytoprotective, biodegradable, UV radiation resistant compositions |
| CN103200826A (en) * | 2010-11-09 | 2013-07-10 | 筑野食品工业株式会社 | Method for producing oil or fat that contains [gamma]-oryzanol |
-
2013
- 2013-08-05 CN CN201310336465.XA patent/CN103445989B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744145A (en) * | 1994-11-05 | 1998-04-28 | Nestec S.A. | Preparation of lipid compositions for cosmetic products |
| US20080233060A1 (en) * | 2007-03-19 | 2008-09-25 | Grune Guerry L | High SPF transparent or translucent, cytoprotective, biodegradable, UV radiation resistant compositions |
| CN103200826A (en) * | 2010-11-09 | 2013-07-10 | 筑野食品工业株式会社 | Method for producing oil or fat that contains [gamma]-oryzanol |
Non-Patent Citations (2)
| Title |
|---|
| 赵陈勇 等: "小米谷糠油降血脂和抗氧化作用的研究", 《中国粮油学报》, vol. 27, no. 7, 31 July 2012 (2012-07-31), pages 67 - 70 * |
| 陆光祟 编译: "米糠提取物与化妆品中的应用", 《中国洗涤用品工业》, no. 3, 31 December 2004 (2004-12-31), pages 43 - 44 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816073A (en) * | 2014-02-19 | 2014-05-28 | 邹琳 | Oligomeric proanthocyanidins chest-enlarging breast maintenance massage agent |
| CN103830148A (en) * | 2014-03-20 | 2014-06-04 | 宁波保税区攀峒信息科技有限公司 | Grain oil and Chinese yam skin-care paste and processing method |
| CN103830146A (en) * | 2014-03-20 | 2014-06-04 | 宁波保税区攀峒信息科技有限公司 | Grain oil and pumpkin skin care cream and processing method thereof |
| CN103860433A (en) * | 2014-03-20 | 2014-06-18 | 宁波保税区攀峒信息科技有限公司 | Cereal oil and sweet potato skin care cream and processing method |
| CN103830148B (en) * | 2014-03-20 | 2016-03-02 | 宁波保税区攀峒信息科技有限公司 | -kind of paddy oil Rhizoma Dioscoreae cold cream and processing method |
| CN103860433B (en) * | 2014-03-20 | 2016-08-24 | 宁波夏光新能源有限公司9 | A kind of paddy oil red potato cold cream and processing method |
| CN105113263A (en) * | 2014-05-14 | 2015-12-02 | 青岛蓝农谷农产品研究开发有限公司 | Antibacterial fiber dipping composition |
| CN106176460A (en) * | 2016-08-30 | 2016-12-07 | 陈燕兰 | A kind of skin care compositions with sun-proof function and preparation method and application |
| CN108042377A (en) * | 2017-12-28 | 2018-05-18 | 广州蜜妆生物科技有限公司 | One kind is planted extraction physical protection breast and preparation method thereof |
| CN108904337A (en) * | 2018-09-21 | 2018-11-30 | 河南中医药大学 | It is a kind of using crude vegetal as the lipstick of raw material |
| CN109172451A (en) * | 2018-10-23 | 2019-01-11 | 天津大学 | A kind of skin-whitening suncream and preparation method thereof |
| CN113197793A (en) * | 2021-04-15 | 2021-08-03 | 广州天玺生物科技有限公司 | Blue light resistant composition and preparation method and application thereof |
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Inventor after: Zhou Xiuqing Inventor before: Wang Changqing Inventor before: Yuan Min |
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Effective date of registration: 20170419 Address after: 510890 Guangzhou, Huadu District, Huadu District, the town of Guangdong Yong Tong Road, No. 1, (for the use of the plant) (23) Patentee after: Guangzhou Shiying Cosmetics Technology Co.,Ltd. Address before: 030006 Taiyuan, Xiaodian District, Shanxi City Road, No. 92 Patentee before: SHANXI University |
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