CN116549323A - Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof - Google Patents

Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof Download PDF

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CN116549323A
CN116549323A CN202310598751.7A CN202310598751A CN116549323A CN 116549323 A CN116549323 A CN 116549323A CN 202310598751 A CN202310598751 A CN 202310598751A CN 116549323 A CN116549323 A CN 116549323A
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skin
emollient
acne
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oiled
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刘星星
陈淘
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Hangzhou Xinyue Cosmetic Co ltd
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Hangzhou Xinyue Cosmetic Co ltd
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Abstract

The application relates to the technical field of cosmetics-cleansing cream, in particular to acne-removing skin-care cleansing cream based on oiled acne muscles and a preparation method thereof. An anti-acne skin care cleansing cream based on oiled acne muscles is mainly prepared from the following raw materials, by weight, 3-4 parts of a skin conditioning agent, 75-80 parts of an emollient, 12-14 parts of an emulsifying agent, 5-6 parts of a thickener-synthetic wax, and 0.15-0.25 part of an antioxidant-tocopherol acetate; the skin conditioner comprises argan kernel oil, stearyl glycyrrhetinate, butanediol, radix salviae miltiorrhizae extract, clove bud extract, radix scutellariae extract, radix angelicae sinensis extract, radix glycyrrhizae extract, centella asiatica extract, bisabolol and centella asiatica extract. The skin care cream is suitable for sensitive skin and oiled acne skin, is mild in makeup removal, can play a role in relieving and repairing skin, and has a good mild makeup removal effect and an acne removal skin care effect.

Description

Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof
Technical Field
The application relates to the technical field of cosmetics-cleansing cream, in particular to acne-removing skin-care cleansing cream based on oiled acne muscles and a preparation method thereof.
Background
With the development of social economy and the improvement of the living standard of people, people pay more attention to the appearance of people, and therefore, the cosmetic modification of the appearance by adopting cosmetics is very common. The market of make-up is increased year by year, and the sun-proof products are skin-care explosive products, but the prior make-up and sun-proof products need make-up removal treatment, but the commercial make-up removal products have relatively poor cleaning effects on make-up and sun-proof products and the like which also contain raw materials such as grease, toner, sun-proof agent, film forming agent and the like, or have better make-up removal effects, but have larger irritation, have loss to skin and do not meet the requirements of consumers.
In order to overcome the defects in the related art, the applicant provides an acne-removing skin-care cleansing cream based on the oiled acne muscles and a preparation method thereof.
Disclosure of Invention
In order to solve the technical problems, the application provides a preparation method of acne-removing skin-care makeup-removing cream based on the oiled acne muscles.
In a first aspect, the application provides an acne removing skin care cleansing cream based on oiled acne muscles, which is realized by the following technical scheme:
an anti-acne skin care cleansing cream based on oiled acne muscles is mainly prepared from the following raw materials, by weight, 3-4 parts of a skin conditioning agent, 75-80 parts of an emollient, 12-14 parts of an emulsifying agent, 5-6 parts of a thickening agent and 0.15-0.25 part of an antioxidant; the antioxidant is tocopheryl acetate; the skin conditioning agents comprise a first skin conditioning agent, a second skin conditioning agent, a third skin conditioning agent, a fourth skin conditioning agent and a fifth skin conditioning agent, wherein the first skin conditioning agent is argania spinosa kernel oil; the second skin conditioner is stearyl glycyrrhetinate; the third skin conditioner is composed of butanediol, radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix Scutellariae extract, radix Angelicae sinensis extract, radix Glycyrrhizae extract, and herba Centellae extract; the fourth skin conditioner is bisabolol; the fifth skin conditioner is centella asiatica extract; the first emollient comprises cetyl ethyl caproate; the second emollient is composed of grape seed oil, sunflower seed oil and wild soybean oil; the third emollient is composed of butter fruit, oil palm oil, jojoba seed oil, tocopherol, and cowberry fruit extract; the fourth emollient is cultivated nigella sativa seed oil; the fifth emollient is squalane; the sixth emollient is jojoba seed oil.
The skin care cream is suitable for sensitive skin and oiled acne skin, is mild in makeup removal, can play a role in relieving and repairing skin, and has a good mild makeup removal effect and an acne removal skin care effect.
Preferably, the mass ratio of the first skin conditioning agent to the second skin conditioning agent to the third skin conditioning agent to the fourth skin conditioning agent to the fifth skin conditioning agent is (18-24): 4-6): 1:1.
The first skin conditioner, argania spinosa kernel oil, contains a large amount of fatty acids, sterols, vitamin E and phenolic compounds. The argania spinosa kernel oil contains a large amount of essential fatty acids, unsaturated fatty acids and linoleic acid, which cannot be synthesized in human bodies and must be obtained from fat. The hydration degree of the fatty acid for maintaining the health of a human body is researched, and the application of linoleic acid on the skin has obvious effects of resisting inflammation, reducing acne and keeping moisture; whereas the lack of essential unsaturated fatty acids can lead to premature aging and wrinkling of the skin; the argania spinosa kernel oil has been scientifically demonstrated to contain 2 times as much vitamin E as olive oil and also contains rare phytosterols which can help soften skin, stimulate pores to expel toxin and restore natural lipid barrier. Polyphenols are well known antioxidants, which not only delay skin aging, but also prolong the duration of action of other antioxidants in the human body, such as vitamin E, vitamin C.
The second skin conditioner, 100% vegetable origin of stearyl glycyrrhetinate, olive oil derivatives, anti-redness and anti-inflammatory, sebum remediation. Stearyl alcohol glycyrrhetinate has antibacterial, antiinflammatory, antioxidant, and antiaging effects. It can also reduce the toxic and side effects of cosmetics or other factors on skin in the cosmetic industry.
The third skin conditioner has good effects of controlling oil, removing acnes and inhibiting acnes.
The fourth skin conditioning agent imparts good anti-inflammatory, anti-irritant, antibacterial and non-carcinogenic properties to the present application.
The centella asiatica extract as the fifth skin conditioner has strong skin pharmacological activity and is used for anti-aging and skin repairing cosmetic products. Centella asiatica extract is an excellent phytoremediation ingredient. Has very good antibacterial effect, and can be used for treating acne; can reduce the generation of pro-inflammatory mediators, improve and repair the self barrier function of skin, thereby preventing and correcting skin immune dysfunction, achieving the anti-inflammatory effect, and being used in cosmetics for repairing after sun, resisting allergy and relieving. The centella asiatica extract also has the promotion effect of fibroblast and collagen synthesis, and can maintain skin elasticity and firmness, and smooth fine wrinkles on face. Centella asiatica extract has a broad market prospect in various personal care fields.
Preferably, the mass ratio of the butanediol, the root extract of red sage, the bud extract of clove, the root extract of baical skullcap root, the root extract of Chinese angelica, the root extract of liquorice and the centella asiatica in the third skin conditioner is 84:8:3:2:1.4:0.8:0.8.
Through the scheme, the third skin conditioner endows the application with good effects of controlling oil, removing acnes and inhibiting acnes, and meanwhile, the production cost is reduced on the premise of ensuring the effect.
Preferably, the mass ratio of the first emollient to the second emollient to the third emollient to the fourth emollient to the fifth emollient to the sixth emollient is (44-48): (24-28): (4-5): (1-2): (1-2): (0.4-0.8).
The first emollient, cetyl alcohol ethyl hexanoate, commonly known as sea bird feather oil, is a soft emollient with particularly excellent waterproof performance, has good air permeability and spreadability, is not sticky and greasy, has thickening effect, and can moisten and soften skin.
The second emollient, grape seed oil, contains various antioxidant substances, protects cells from oxidative damage, delays aging process, is high in freshness, is not greasy, and has extremely high permeability. The grape seed oil is rich in polyunsaturated fatty acid, has an antioxidant function, and is helpful for repairing and brightening skin; the sunflower seed oil is an important base oil raw material of cosmetics, has the effects of lubricating skin, activating a peroxidase activated receptor, promoting skin wound healing and resisting inflammation, has a certain inhibition effect on tyrosinase, and has the whitening effect.
The third emollient is soft sweet, has strong antioxidant effect, has fine cranberry particles, and can be mixed with other organic certification ingredients to form soft and comfortable skin feel and good spreadability.
And fourthly, cultivating the black grass seed oil by using the emollients, wherein the cultivated black grass seed oil contains fixed oil, and the main component of the seed oil is saponin, so that the seed oil can lubricate, clean skin and condition the secretion of grease on the skin. The black grass is extremely rich in unsaturated fatty acid content, so that the black grass can be qualified as a name of 'skin food', can nourish, pacify, soften and dry skin, improve eczema, psoriasis, dermatitis and acne, is excellent in overnight repair and care oil, can greatly improve the overall condition of skin after regular use, can increase skin fineness and softness, and has the effect of reducing wrinkles.
The fifth emollient squalane is extracted from olive oil, is a natural component in skin, has good effects of resisting oxidization and stimulating immunity, can be quickly dissolved with moisture and grease in skin to form a natural skin protection barrier, has excellent stability, can not generate oxidization with air, ultraviolet rays and the like, can effectively protect the skin from being affected by external substances, has excellent penetrability and high-efficiency oxygen carrying property, can regulate the water-oil balance of the skin, avoids the roughness and darkness of the skin, and enables the skin to recover the original tender touch. Is especially suitable for use in cold season, is lubricating oil for skin, and can supplement natural sebum for skin.
Besides the vitamin a, the vitamin b and the vitamin e which are very rich in the sixth emollient, the jojoba seed oil also contains minerals such as calcium, magnesium and the like, has better permeability, can improve the stability and the efficacy of the application, and helps the skin to solve the skin blemish problems such as dryness, lack of water, roughness, darkness and the like.
Preferably, the grape seed oil, the sunflower seed oil and the wild soybean oil in the second emollient are formed by the mass ratio of 40:30:30; the butter fruit oil, oil palm oil, jojoba seed oil, tocopherol and cranberry fruit extract in the third emollient are prepared according to a mass ratio of 43.75:45:5.5:0.25:5.5.
Preferably, the emulsifying agent comprises a first emulsifying agent, a second emulsifying agent and a third emulsifying agent, wherein the first emulsifying agent is PEG-20 glycerol triisostearate, and the second emulsifying agent is polyglycerol-10 dioleate; the third emulsifier is composed of jojoba esters, sunflower seed wax, acacia negra flower wax, polyglycerol-3 and tocopherol.
Preferably, the mass ratio of the first emulsifier to the second emulsifier to the third emulsifier is (8-12) 1:1.
Preferably, the mass ratio of jojoba esters, sunflower seed wax, acacia negra wax, polyglycerol-3 and tocopherol in the third emulsifier is 62:32:2.98:3:0.02.
S1, mixing 100g of 300-500-mesh coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500-mL three-neck flask, stirring uniformly by using ultrasonic waves, heating to 140-155 ℃ by an oil bath, controlling the heating speed to 4-6 ℃/min, maintaining the temperature at 140-155 ℃ for 20-30min, cooling to room temperature, centrifuging, separating, cleaning, and naturally drying to obtain the coffee grounds with zinc particles on the surface; s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to the mass ratio of 1:1:1:1:1 to form composite amino acid, 20-40g of the composite amino acid is weighed and dissolved in 100-1000mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained; s3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with the sodium hydroxide to form zinc hydroxide, adding the zinc particles on the surfaces of the coffee grounds treated by the sodium hydroxide into the compound amino acid solution obtained in the S2, reacting the compound amino acid with zinc ions in a molar ratio of = 2:1, heating the water bath to 80-85 ℃ to react, simultaneously, continuously dropwise adding 0.1-0.3moL of sodium hydroxide solution to react for 6-8h, filtering to remove unreacted insoluble substances, adding an acetone solution to treat, draining, and drying at 60-65 ℃ to obtain the surface modified coffee grounds.
The effect of the cleansing experience of the cleansing cream can be improved by introducing the coffee grounds in the cleansing cream, the cleansing experience of consumers is improved, and therefore the cleansing cream is easier to accept by mass consumers and is convenient to be brought to the market. According to the preparation method, the active anti-inflammatory and antibacterial carrier formed by introducing the compound amino acid and zinc ions on the surface of the coffee grounds can play roles in relieving, diminishing inflammation, resisting bacteria and repairing skin, and the market competitiveness of the product is improved.
In a second aspect, the preparation method of the acne-removing skin-care makeup-removing cream based on the oiled acne muscles is realized through the following technical scheme:
a preparation method of acne-removing skin-care cleansing cream based on oiled acne muscles comprises the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a first thickener, a first skin conditioner, a second emulsifier, a second thickener and a sixth emollient into a pot, starting stirring and heating at 500-600rpm, heating to 85+/-5 ℃, adding a second skin conditioner, a fourth skin conditioner and an antioxidant serving as raw material components after materials are completely melted, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioning agent and the fifth skin conditioning agent into a clean stainless steel barrel, heating to 80+/-5 ℃, stirring until the components are uniformly melted, slowly adding into a pot, and stirring for 10-20min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and when the material body is taken out of the pot, filtering is carried out, and a filter screen is 80-100 meshes.
The preparation method is relatively simple, low in operation difficulty and convenient to realize industrial production and manufacture.
In summary, the present application has the following advantages:
1. the skin care cream is suitable for sensitive skin and oiled acne skin, is mild in makeup removal, can play a role in relieving and repairing skin, and has a good mild makeup removal effect and an acne removal skin care effect.
2. The preparation method is relatively simple, low in operation difficulty and convenient to realize industrial production and manufacture.
Detailed Description
The present application is described in further detail below in conjunction with comparative examples and examples.
Preparation example
Preparation example 1
The preparation method of the surface modified coffee grounds comprises the following steps:
s1, mixing 100g of 500-mesh coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500-mL three-neck flask, stirring by using ultrasonic until the mixture is uniformly dispersed, heating to 145 ℃ by using an oil bath, controlling the heating speed to 5 ℃/min, maintaining the temperature at 145 ℃ for 20-30min, cooling to room temperature, centrifuging, separating, cleaning, and naturally drying to obtain the coffee grounds with zinc particles on the surface;
s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to a mass ratio of 1:1:1:1:1 to form composite amino acid, 40g of the composite amino acid is weighed and dissolved in 500mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained;
and S3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with sodium hydroxide to form zinc hydroxide, adding the coffee grounds with zinc particles on the surfaces treated by sodium hydroxide into the compound amino acid solution obtained in the S2, reacting the compound amino acid with zinc ions in a molar ratio of = 2:1, heating the water bath to 80 ℃ for reaction, simultaneously, continuously dropwise adding 0.15moL of sodium hydroxide solution for reaction for 8.0h, filtering to remove unreacted insoluble substances, adding an acetone solution for treatment, draining, and drying at 60 ℃ to obtain the surface modified coffee grounds.
Preparation example 2
Preparation 2 differs from preparation 1 in that: and S1, performing activation treatment on the 500-mesh coffee grounds at 275 ℃ for 2 hours to obtain the 500-mesh activated coffee grounds.
Preparation example 3
Preparation 3 differs from preparation 1 in that: s2, mixing aspartic acid, serine and lysine according to the mass ratio of 1:1:1 to form composite amino acid, weighing 20-40g of the composite amino acid, dissolving in 100-1000mL of pure water, stirring, and filtering to remove undissolved components to obtain the composite amino acid solution.
Examples
An acne removing skin care cleansing cream based on oiled acne muscles is mainly prepared from the following raw materials in parts by weight: 3-4 parts of skin conditioning agent, 75-80 parts of emollient, 12-14 parts of emulsifier, 5-6 parts of thickener and 0.15-0.25 part of antioxidant.
The antioxidant is tocopheryl acetate. The thickener is synthetic wax.
The skin conditioning agents comprise a first skin conditioning agent, a second skin conditioning agent, a third skin conditioning agent, a fourth skin conditioning agent and a fifth skin conditioning agent, and the mass ratio of the first skin conditioning agent to the second skin conditioning agent to the third skin conditioning agent to the fourth skin conditioning agent to the fifth skin conditioning agent is (18-24): (4-6): (4-6): 1:1.
the first skin conditioner is argania spinosa kernel oil.
The second skin conditioner is stearyl glycyrrhetinate.
The third skin conditioner comprises butanediol, saviae Miltiorrhizae radix extract, flos Caryophylli bud extract, scutellariae radix extract, radix Angelicae sinensis extract, glycyrrhrizae radix extract, and herba Centellae extract.
The mass ratio of butanediol, radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix Scutellariae extract, radix Angelicae sinensis extract, radix Glycyrrhizae extract, and herba Centellae extract in the third skin conditioner is 84:8:3:2:1.4:0.8:0.8.
The fourth skin conditioner is bisabolol.
The fifth skin conditioner is centella asiatica extract.
The emollients comprise a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient and a sixth emollient, and the mass ratio of the first emollient, the second emollient, the third emollient, the fourth emollient, the fifth emollient and the sixth emollient is (44-48): (24-28): (4-5): (1-2): (1-2): (0.4-0.8).
The first emollient is cetyl ethyl hexanoate.
The second emollient is composed of grape seed oil, sunflower seed oil and wild soybean oil, wherein the mass ratio of grape seed oil, sunflower seed oil and wild soybean oil is 40:30:30.
The third emollient is composed of butter fruit oil, oil palm oil, jojoba seed oil, tocopherol, and cranberry fruit extract, wherein the mass ratio of butter fruit oil, oil palm oil, jojoba seed oil, tocopherol, cranberry fruit extract is 43.75:45:5.5:0.25:5.5.
The fourth emollient is cultivated nigella sativa seed oil.
The fifth emollient is squalane.
The sixth emollient is jojoba seed oil.
The emulsifying agent comprises a first emulsifying agent, a second emulsifying agent and a third emulsifying agent, wherein the mass ratio of the first emulsifying agent to the second emulsifying agent to the third emulsifying agent is (8-12) 1:1. The first emulsifier is PEG-20 triisostearate, the second emulsifier is polyglycerol-10 dioleate, and the third emulsifier is composed of jojoba esters, sunflower seed wax, acacia wax, polyglycerol-3 and tocopherol. The mass ratio of jojoba esters, sunflower seed wax, vitex negundo flower wax, polyglycerol-3 and tocopherol is 62:32:2.98:3:0.02.
In addition, 3-6 parts of 300-500 mesh surface modified coffee grounds are included.
The preparation method of the surface modified coffee grounds comprises the following steps:
s1, mixing 100g of 300-500 meshes of coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500mL three-neck flask, stirring by using ultrasonic until the mixture is uniformly dispersed, heating to 140-155 ℃ by using an oil bath, controlling the heating speed to 4-6 ℃/min, maintaining the temperature at 140-155 ℃ for 20-30min, cooling to room temperature, centrifuging, separating, cleaning, naturally drying, and obtaining the coffee grounds with zinc particles on the surface;
s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to the mass ratio of 1:1:1:1:1 to form composite amino acid, 20-40g of the composite amino acid is weighed and dissolved in 100-1000mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained;
s3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with the sodium hydroxide to form zinc hydroxide, and then adding the coffee grounds with the zinc particles on the surfaces treated by the sodium hydroxide into the compound amino acid solution obtained in the S2, wherein the compound amino acid comprises the following steps of: the molar ratio of zinc ions=2:1 is reacted, the water bath is heated to 80-85 ℃ for reaction, 0.1-0.3moL of sodium hydroxide solution is continuously added dropwise for reaction for 6-8 hours, unreacted insoluble substances are removed by filtration, then acetone solution is added for treatment, and the surface modified coffee grounds are obtained after draining and drying at 60-65 ℃.
See in particular the surface-modified coffee grounds obtained in preparation examples 1-3.
A preparation method of acne-removing skin-care cleansing cream based on oiled acne muscles comprises the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a thickener, a first skin conditioner, a second emulsifier and a sixth emollient into a pot, starting stirring and heating at 500-600rpm, heating to 85+/-5 ℃, adding a second skin conditioner, a fourth skin conditioner and an antioxidant serving as raw material components after materials are completely melted, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioning agent and the fifth skin conditioning agent into a clean stainless steel barrel, heating to 80+/-5 ℃, stirring until the components are uniformly melted, slowly adding into a pot, and stirring for 10-20min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and when the material body is taken out of the pot, filtering is carried out, and a filter screen is 80-100 meshes.
Examples 1 to 4
The application discloses an acne removing skin care cleansing cream based on oiled acne muscles, and the formula is shown in table 1:
table 1 shows the formulation of the acne-removing skin-care cleansing cream of examples 1 to 4
A preparation method of acne-removing skin-care cleansing cream based on oiled acne muscles comprises the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a thickener, a first skin conditioner, a second emulsifier and a sixth emollient into a pot, starting stirring and heating, heating at a stirring speed of 500rpm, heating to 85 ℃, adding a raw material component of the second skin conditioner, the fourth skin conditioner and an antioxidant after the materials are completely dissolved, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioner and the fifth skin conditioner in a clean stainless steel barrel, heating to 80 ℃, stirring until the components are melted uniformly, slowly putting into a pot, and stirring for 15min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and the material body is filtered when being taken out of the pot, and a filter screen is 80-100 meshes, so that a finished product is obtained.
Examples 5 to 9
The differences between examples 5-9 and example 1 are as follows in Table 2:
table 2 shows the formulation of the acne-removing skin-care cleansing cream of examples 5 to 9
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Examples 10 to 12
Examples 10-12 differ from example 1 as shown in Table 3 below:
table 3 shows the formulation of the acne-removing skin-care cleansing cream of examples 10 to 12
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Comparative example
Comparative examples 1-4 differ from example 1 in table 4 below:
table 4 is a formulation table of the acne-removing skin-care cleansing cream of comparative examples 1 to 4
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Comparative example 5 is a Dior rose extract cleansing cream.
Performance test
Detection method/test method
The test evaluation method comprises the following steps:
test volunteers 10, requirement: the ages are between 16 years and 65 years; patients with no serious systemic disease, no immunodeficiency or autoimmune disease; patients with no active allergic disease; the prior skin care cosmetics have no serious allergic history; hormonal drugs and immunosuppressants have not been used for about 1 month; those who did not participate in other clinical trials; the test object is used according to the specification and the data is complete; all volunteers should fill in informed consent prior to testing.
Test object: acne-removing skin-care cleansing cream in examples 1 to 12 and comparative examples 1 to 5.
The testing method comprises the following steps: the acne-removing skin-care cleansing cream of examples 1 to 12 and comparative examples 1 to 5 were put into plastic barrels of the same size and were used by the testers after the products were in the order of the sequential labels A1, A2, A3, A4, B1, B2, B3, B4, B5, C1, C2, C3, D1, D2, D3, D4, E. The test time is 12 days, and the cleansing performance, the mildness (sensitivity) performance, the acne removal performance and the skin care performance of the product are evaluated by using the product once a day in the morning and evening.
The evaluation effect was classified into 4 grades, grade 1 being poor, grade 2 being general, grade 3 being better, grade 4 being good.
Data analysis
Table 5 is a table of the makeup removing performance test parameters of the acne-removing skin care makeup removing cream of examples 1 to 12 and comparative examples 1 to 4
Table 6 is a table of comprehensive performance test parameters of the anti-acne skin care cleansing cream of examples 1 to 12 and comparative examples 1 to 4
Comprehensive makeup removing performance Mild Properties Acne-removing property Skin care properties
Example 1 3.804 3.72 3.58 3.82
Example 2 3.764 3.58 3.55 3.76
Example 3 3.772 3.63 3.46 3.72
Example 4 3.618 3.55 3.42 3.68
Example 5 3.712 3.68 3.54 3.61
Example 6 3.716 3.70 3.45 3.54
Example 7 3.766 3.73 3.42 3.49
Example 8 3.774 3.69 3.42 3.45
Example 9 3.804 3.70 3.45 3.51
Example 10 3.802 3.65 3.60 3.85
Example 11 3.826 3.68 3.63 3.87
Example 12 3.744 3.61 3.55 3.84
Comparative example 1 3.410 3.65 3.55 3.78
Comparative example 2 2.896 3.58 3.57 3.75
Comparative example 3 3.574 3.55 2.85 2.91
Comparative example 4 3.592 3.61 2.92 2.83
Comparative example 5 3.782 3.70 3.42 3.75
As can be seen from a combination of examples 1-12 and comparative examples 1-5 and from a comparison of tables 5-6, example 1 and comparative examples 1-2 demonstrate that the three types of emulsifiers used in the present application, combined, provide improved overall cleansing and mildness, and reduced skin irritation.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and the combination of tables 5-6, the skin conditioning agents obtained by compounding the five skin conditioning agents used in the application can improve the acne removing performance and the skin care performance of the application, have positive effects on the makeup removing performance and reduce the irritation to the skin as compared with comparative example 3.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and the combination of tables 5-6, the use of the six emollients in the present application results in an emollient that improves the anti-acne and skin care properties of the present application, has a positive effect on the anti-makeup properties, and reduces skin irritation.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and the combination of tables 5-6, the acne-removing skin-care cleansing cream prepared in the present application is comparable to the hot-spot dio rose extract cleansing cream in terms of performance, and the present application has a market competitive advantage.
As can be seen by combining examples 1-12 and comparative examples 1-5 and combining tables 5-6, the anti-acne skin care cleansing cream prepared by the example 1 and the example 2-4 has better effects of relieving and repairing skin and removing acnes, and is suitable for sensitive muscles and oilpox skin.
As can be seen by combining examples 1-12 and comparative examples 1-5 and combining tables 5-6, the comparison between examples 1 and 5-9 shows that the skin care cream prepared by the mass ratio of the first skin conditioner to the second skin conditioner to the third skin conditioner to the fourth skin conditioner to the fifth skin conditioner is (18-24): 4-6): 4-6:1:1 has better skin care effect and acne care effect, and is suitable for sensitive muscles and oilpox skin.
As can be seen from the combination of examples 1-12 and comparative examples 1-5 and tables 5-6, the surface modified coffee grounds added in the present application can improve the acne removing effect and skin care performance of the present application, and have less skin irritation and mild cleansing effect.
In conclusion, the acne-removing and skin-care cream is suitable for skin quality of sensitive muscles and oilacnes, and can be used for mildly removing makeup, and simultaneously has the effect of relieving and repairing the skin, namely, has a good mildly removing makeup effect and has the acne-removing and skin-care effects.
The present embodiment is merely illustrative of the present application and is not intended to be limiting, and those skilled in the art, after having read the present specification, may make modifications to the present embodiment without creative contribution as required, but is protected by patent laws within the scope of the claims of the present application.

Claims (10)

1. An anti-acne skin care cleansing cream based on oiled acne muscles is characterized by being prepared from the following raw materials, by weight, 3-4 parts of a skin conditioning agent, 75-80 parts of an emollient, 12-14 parts of an emulsifying agent, 5-6 parts of a thickening agent and 0.15-0.25 part of an antioxidant; the antioxidant is tocopheryl acetate; the thickener is synthetic wax.
2. The acne-removing skin care cleansing cream based on the oiled poxus muscles, which is characterized in that the skin conditioning agents comprise a first skin conditioning agent, a second skin conditioning agent, a third skin conditioning agent, a fourth skin conditioning agent and a fifth skin conditioning agent, wherein the first skin conditioning agent is argania spinosa kernel oil; the second skin conditioner is stearyl glycyrrhetinate; the third skin conditioner is composed of butanediol, radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix Scutellariae extract, radix Angelicae sinensis extract, radix Glycyrrhizae extract, and herba Centellae extract; the fourth skin conditioner is bisabolol; the fifth skin conditioner is centella asiatica extract; the mass ratio of the first skin conditioning agent to the second skin conditioning agent to the third skin conditioning agent to the fourth skin conditioning agent to the fifth skin conditioning agent is (18-24): 4-6): 1:1.
3. The acne-removing skin-care cleansing cream based on the oiled poxes according to claim 1 or 2, wherein the mass ratio of the butanediol to the root extract of red sage to the bud extract of clove to the root extract of baical skullcap, the root extract of angelica to the root extract of liquorice to the centella asiatica is 84:8:3:2:1.4:0.8:0.8.
4. The acne-removing skin care cleansing cream based on the oiliness skin according to claim 1, wherein the emollient comprises a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient and a sixth emollient, and the first emollient is cetyl ethyl caproate; the second emollient is composed of grape seed oil, sunflower seed oil and wild soybean oil; the third emollient is composed of butter fruit, oil palm oil, jojoba seed oil, tocopherol, and cowberry fruit extract; the fourth emollient is cultivated nigella sativa seed oil; the fifth emollient is squalane; the sixth emollient is jojoba seed oil; the mass ratio of the first emollient to the second emollient to the third emollient to the fourth emollient to the fifth emollient to the sixth emollient is (44-48): (24-28): (4-5): (1-2): (1-2): (0.4-0.8).
5. The acne-removing skin-care cleansing cream based on the oiled acne muscles, which is characterized in that grape seed oil, sunflower seed oil and wild soybean oil in the second emollient are prepared according to a mass ratio of 40:30:30; the butter fruit oil, oil palm oil, jojoba seed oil, tocopherol and cranberry fruit extract in the third emollient are prepared according to a mass ratio of 43.75:45:5.5:0.25:5.5.
6. The acne-removing skin care cleansing cream based on the oiled poxy muscles according to claim 4, wherein the emulsifying agent comprises a first emulsifying agent, a second emulsifying agent and a third emulsifying agent, wherein the first emulsifying agent is PEG-20 glycerol triisostearate, and the second emulsifying agent is polyglycerol-10 dioleate; the third emulsifier is composed of jojoba esters, sunflower seed wax, acacia negra flower wax, polyglycerol-3 and tocopherol.
7. The acne-removing skin care cleansing cream based on the oiled poxes according to claim 6, wherein the mass ratio of the first emulsifier to the second emulsifier to the third emulsifier is (8-12): 1:1.
8. The acne-removing skin-care cleansing cream based on the oiled poxes according to claim 6, wherein the mass ratio of jojoba esters, sunflower seed wax, vitex negundo flower wax, polyglycerol-3 and tocopherol in the third emulsifier is 62:32:2.98:3:0.02.
9. The acne-removing skin care cleansing cream based on the oiled poxes according to claim 6 is characterized by further comprising 3-6 parts of 300-500 mesh surface modified coffee grounds, wherein the preparation method of the surface modified coffee grounds comprises the following steps of S1, mixing 100g of 300-500 mesh coffee grounds, 30-40g of zinc nitrate and 300-400mL of ethylene glycol into a 500mL three-neck flask, stirring uniformly by using ultrasonic waves, heating to 140-155 ℃ by using an oil bath, controlling the heating speed to 4-6 ℃/min, maintaining the temperature at 140-155 ℃ for 20-30min to be reduced to room temperature, centrifuging, cleaning, and naturally drying to obtain the coffee grounds with zinc particles on the surface; s2, aspartic acid, glycine, alanine, serine, valine and lysine are mixed according to the mass ratio of 1:1:1:1:1 to form composite amino acid, 20-40g of the composite amino acid is weighed and dissolved in 100-1000mL of pure water, and insoluble components are removed through stirring and filtration, so that a composite amino acid solution is obtained; s3, reacting the coffee grounds with zinc particles on the surfaces in the S1 with sodium hydroxide to enable zinc nanoclusters loaded on the surfaces of the coffee grounds to react with the sodium hydroxide to form zinc hydroxide, adding the zinc particles on the surfaces of the coffee grounds treated by the sodium hydroxide into the compound amino acid solution obtained in the S2, reacting the compound amino acid with zinc ions in a molar ratio of = 2:1, heating the water bath to 80-85 ℃ to react, simultaneously, continuously dropwise adding 0.1-0.3moL of sodium hydroxide solution to react for 6-8h, filtering to remove unreacted insoluble substances, adding an acetone solution to treat, draining, and drying at 60-65 ℃ to obtain the surface modified coffee grounds.
10. A method for preparing the acne-removing skin-care makeup-removing cream based on the oiled poxes according to claim 9, which is characterized by comprising the following steps:
firstly, putting a first emollient, a second emollient, a third emollient, a fourth emollient, a fifth emollient, a first emulsifier, a thickener, a first skin conditioner, a second emulsifier and a sixth emollient into a pot, starting stirring and heating at 500-600rpm, heating to 85+/-5 ℃, adding a second skin conditioner, a fourth skin conditioner and an antioxidant serving as raw material components after materials are completely melted, and stirring until the materials are completely dissolved;
step two, independently placing the third emulsifier, the third skin conditioning agent and the fifth skin conditioning agent into a clean stainless steel barrel, heating to 80+/-5 ℃, stirring until the components are uniformly melted, slowly adding into a pot, and stirring for 10-20min until the components are completely dispersed;
and thirdly, vacuum defoamation is carried out on the material body in the pot, the standard is that no bubble exists on the surface of the material body, the completion of vacuum bubble suction is confirmed, the material body is sampled and sent to a product pipe for detection, and when the material body is taken out of the pot, filtering is carried out, and a filter screen is 80-100 meshes.
CN202310598751.7A 2023-05-22 2023-05-22 Acne-removing skin-care cleansing cream based on oiled acne muscles and preparation method thereof Pending CN116549323A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117427018A (en) * 2023-12-22 2024-01-23 广州海龟爸爸生物科技有限公司 Centella asiatica extract and transparent zinc oxide sun-screening composition and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117427018A (en) * 2023-12-22 2024-01-23 广州海龟爸爸生物科技有限公司 Centella asiatica extract and transparent zinc oxide sun-screening composition and application thereof
CN117427018B (en) * 2023-12-22 2024-03-12 广州海龟爸爸生物科技有限公司 Centella asiatica extract and transparent zinc oxide sun-screening composition and application thereof

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