CN106727013A - A kind of anti-apolexis composition and its application - Google Patents

A kind of anti-apolexis composition and its application Download PDF

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Publication number
CN106727013A
CN106727013A CN201710007079.4A CN201710007079A CN106727013A CN 106727013 A CN106727013 A CN 106727013A CN 201710007079 A CN201710007079 A CN 201710007079A CN 106727013 A CN106727013 A CN 106727013A
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alcohol
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杨凯
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Guangzhou Poly Health Industry Research Institute Co Ltd
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Guangzhou Poly Health Industry Research Institute Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

Abstract

The present invention relates to cosmetic field, and in particular to a kind of anti-apolexis composition and its application.Composition by following weight portion material composition：Fall down to the ground 48 parts of tinkling of pieces of jade extract, 25 parts of limonene, 46 parts of kudzu root extract, 38 parts of evening primrose oil.Applied in anti-aging face cream, arranged in pairs or groups according to specific ratio, reconciled mutually rich in multiple efficacies composition, cooperateed with, be that skin becomes delicate, it is smooth, flexible, reach good anti-aging effects.Meanwhile, compounding addition can inhibiting bacteria and diminishing inflammation, the french lavender extract of skin care, the Butyrospermum parkii fruit fat of antiultraviolet, the Sodium Hyaluronate of powerful water lock moisturizing adds the Penetration enhancing effect of butanediol, the features such as imparting this product good penetrability, good stability, salubrious non-greasy.

Description

A kind of anti-apolexis composition and its application
Technical field
The present invention relates to cosmetic field, and in particular to a kind of anti-apolexis composition and its application.
Background technology
At every moment all aging, its elasticity is slowly reduced skin, and thin down, it is more and more fragile and lax, The visual impression for giving people is exactly to be wrinkled, and skin aging typically has the two kinds of form of expression-natural agings and light aging.The former Refer mainly to age, by such as heredity, gravity, endocrine and the immunologic function that exist in body factor can not be resisted to cause It is aging；The latter accelerates the process of naturally-aged mainly due to the effect of ultraviolet, and climate change and environmental pollution A series of light aging etc. environmental exposures on skin also has directly influence.Moisture content in skin reduction will cause albumen Enzymatic activity reduction, so as to trigger the phenomenons such as decortication.Oxidation is the threat maximum to skin, diet is unhealthy, Exposure to Sunlight, pressure, ring Border pollution etc. can allow skin free radical to spread unchecked, so as to produce the oxidative phenomenas such as complexion dimness, water shortage.Accordingly, it would be desirable to daily Note in life anti-oxidant.Main path includes：Protect the skin from external environment stimulation；Many cofree in scavenger-cell Base；Skin Cell is repaired and is supplemented the nutrients.Skin anti-aging is to prevent skin from gradually property work(occurring because the time elapses Can be sexually revised with organic moving back.Anti-aging cosmetics are exactly the cosmetics for realizing senile-resistant efficacy, are that important effect type is made up One of product.
It is most of to there is more chemical synthesis although the various anti-aging skin care products of commercial type emerge in an endless stream , there is easy allergy, absorption difference, greasy in material, the problems such as anti-aging effects are bad.
The content of the invention
It is an object of the invention to provide a kind of anti-apolexis composition and its application.
The present invention provide a kind of anti-apolexis composition, the composition by following weight portion material composition：Fall down to the ground the tinkling of pieces of jade Extract 1-3 parts, limonene 0.2-0.5 parts, kudzu root extract 0.4-1.6 parts, evening primrose oil 3-6 parts.
A kind of anti-apolexis composition that the present invention is provided, the preparation method of the cardiospermum halicacabum extract is：
(1) dry cardiospermum halicacabum is ground into the cardiospermum halicacabum material powder that average grain diameter is 20~70 mesh；
(2) the cardiospermum halicacabum material powder obtained in step (1) is put into extraction vessel, to 15 times of addition in extraction vessel 75% ethanol solution, refluxing extraction 5 times, 2 hours every time, concentration, cardiospermum halicacabum extract is obtained after dry, pulverize.
A kind of anti-apolexis composition that the present invention is provided, the preparation method of the kudzu root extract is：
(1) the fresh root of kudzu vine is taken, clean dry is ground into coarse grain, coarse grain water boiling and extraction 3 times, each 2h of decocting time, Merge filtrate twice, stand 2h, filtering, filtrate is standby；
(2) step (1) gained filtrate decompression is concentrated to give thick medicinal extract, thick medicinal extract is spray-dried (inlet temperature 180 DEG C, 70 DEG C of outlet temperature), dried medicinal extract is ground into the fine powder of 70 mesh sizes, obtain final product the kudzu root extract.
Application of the anti-apolexis composition that the present invention is provided in cosmetics are prepared.
Application of the anti-apolexis composition that the present invention is provided in cosmetics are prepared.The cosmetics are anti-aging face cream.
A kind of anti-aging face cream that the present invention is provided is made up of the raw material of following weight portion：Anti-apolexis composition 4.6-11.1 Part；C14-22 alcohol/1.5-2 parts of C12-20 alkyl glucosides；Stearine/1.2-1.8 parts of PEG-100 stearates；Whale 1.8-2.2 parts of wax stearyl alcohol；Saualane 2.5-3.5 parts；Dimethyl silicone polymer 1-3 parts；Caprylic/capric triglyceride 2-4 parts； 1-3 parts of Butyrospermum parkii fruit fat；Hydrogenated jojoba oil 1-3 parts；0.2-0.8 parts of french lavender extract；Methyl hydroxybenzoate 0.1-0.2 Part；Nipasol 0.1-0.2 parts；Sodium Hyaluronate 0.01-0.04 parts；Xanthans 0.1-0.14 parts；Glycerine 1-4 parts；Poly- second two Alcohol -83-7 parts；Polyacrylamide/C13-14 isoparaffins/laureth -70.2-0.6 parts；Dimethyl silicone polymer/poly- two 0.2-0.6 parts of methylsiloxane alcohol；Butanediol 1-2 parts；Bis(hydroxymethyl)imidazolidinyl urea 0.1-0.3 parts；Deionized water 35-70 Part.
The present invention also provides the preparation method of anti-aging face cream, and the preparation method is comprised the following steps：
1) by C14-22 alcohol/C12-20 alkyl glucosides, stearine/PEG-100 stearates, cetearyl alcohol Alcohol, saualane, dimethyl silicone polymer, caprylic/capric triglyceride, Butyrospermum parkii fruit fat, hydrogenated jojoba oil, France smoke clothing Careless extract, methyl hydroxybenzoate, Nipasol mixing put into oil phase pot heating stirring to 85 degree as A phases, after stirring and dissolving is complete Heat preservation for standby use；
2) Sodium Hyaluronate, xanthans, glycerine, PEG-8 are mixed as B and is added to heating stirring in water phase pot To 85 degree, the completely rear heat preservation for standby use of stirring and dissolving；
3) emulsification pot is preheated to 60-65 degree, first be pumped into for B phases by 50 revs/min of mixing speed, then A phases are pumped into, and is stirred Mix 30 minutes, temperature is maintained at 85 degree；
4) C is added to emulsification pot, homogeneous 3 minutes, insulated and stirred 30 minutes, temperature is maintained at 80-85 degree, mixing speed 35 revs/min；The C phases are polyacrylamide/C13-14 isoparaffins/laureth -7；
5) being cooled to 42 degree adds D phases and E phases, insulated and stirred 10 minutes, 25-30 revs/min of mixing speed to be eventually adding F phases, are incubated 10-20 minutes；The D phases are polydimethyl siloxanes/polydimethy siloxanes alcohol, and the E phases are anti-aging group Compound, butanediol, the F phases are Bis(hydroxymethyl)imidazolidinyl urea；
6) stirring is cooled to 40 degree of dischargings.
Effect or feature of main component of the present invention are as follows:
Falling down to the ground can be with containing bioactivator stigmasterol and rutin stigmasterol with senile-resistant efficacy in tinkling of pieces of jade extract By strengthening cellular superoxide dismutase (SOD) vigor, reducing Plasma MDA (MDA) horizontal scavenging activated oxygen, reduce The lipid peroxidation of cell membrane, maintains the softness and moistening of cell, keeps skin surface moisture content, promotes skin new old generation Thank.Rutin is 3 rutinosides of Quercetin, containing phenolic hydroxyl structure, can be with active oxygen radical reaction generation resonance stabilized Half quinoid free radical, terminate free chain reaction, play antioxidation, phosphatide and lipoids peroxide can be suppressed Formed, and the activity of other antioxidants can be strengthened, the clearance rate to active oxygen radical is up to 78.1%.
Limonene rich content in orange oil, is a kind of natural activity monoterpene, has good suppression to the rotten bacterium of common cause Effect.Rutin coordinates with limonene in the present invention, has good inhibitory action, 50 μm of concentration of ol/L to the formation of active oxygen More than 60% oxygen radical can be eliminated.
Contained Puerarin and flavones have oestrogen-like hormone characteristic and expansion of blood vessels, increase CBF, accelerate micro- in the root of kudzu vine Effect of vascular flow speed, and the catalysis activity of tyrosinase can be significantly inhibited, oxidation of melanin process is interrupted, so as to suppress The generation of melanin and formation, have functions that whitening spot-removing.
Aliphatic acid in evening primrose oil is easily absorbed by the skin, and stimulates circulation, and prevents epidermal cell angling, delays to decline Always.Good moisturizing agent and NMF can be done in the product.Redsepal evening primrose flower contains aromatic alcohol and its derivative, can adjust sebaceous glands Metabolism, improves cutaneous disorder phenomenon, whelk and blackspot that treatment endocrine causes.
Butyrospermum parkii fruit fat contains cinnamate, the injury that can prevent ultraviolet Irradiation on Skin from causing, its day for containing Right latex be also prevented from by sunlight cause it is allergic.
The beneficial effects of the invention are as follows：(1) anti-apolexis composition of the invention with the addition of the tinkling of pieces of jade extract that falls down to the ground, the root of kudzu vine and extract Thing, evening primrose oil and limonene, are arranged in pairs or groups according to specific ratio, are reconciled mutually rich in multiple efficacies composition, cooperateed with, and are skins Skin becomes delicate, smooth, flexible, reaches good anti-aging effects；(2) in anti-apolexis composition of the present invention, cardiospermum halicacabum Containing the Quercetin and rutin for absorbing ultraviolet in extract, the root of kudzu vine suppresses the formation of melanin, and evening primrose oil regulation sebum prolongs Slow aging, compounding addition can inhibiting bacteria and diminishing inflammation, the french lavender extract of skin care, the Butyrospermum parkii fruit fat of antiultraviolet, The Sodium Hyaluronate of powerful water lock moisturizing, adds the Penetration enhancing effect of butanediol, imparts this product good penetrability, stability Well, the features such as salubrious non-greasy；(3) active ingredient of the present invention is safe and non-stimulating, has nutrition and moisten effect concurrently, by trying repeatedly Test, this recipe ingredient ratio can reach ready-made product efficacy, effectively antagonize free radical, delay skin aging resists with good Aging ability.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
The following component title occurred in text is INCI (Internation Nomenclaure Cosmetic Ingredent, i.e. international cosmetic raw material name) institute to regulation title：C14-22 alcohol/C12-20 alkyl glucosides, glycerine Stearate/PEG-100 stearates, caprylic/capric triglyceride, polyacrylamide/C13-14 isoparaffins/laruyl alcohol gather Ether -7, polydimethyl siloxanes/polydimethy siloxanes alcohol.
The anti-aging face cream formula of the embodiment of the present invention 1~5 is shown in Table 1
Table 1
Anti-aging face cream preparation method of the present invention is comprised the following steps：
1) by C14-22 alcohol/C12-20 alkyl glucosides, stearine/PEG-100 stearates, cetearyl alcohol Alcohol, saualane, dimethyl silicone polymer, caprylic/capric triglyceride, Butyrospermum parkii fruit fat, hydrogenated jojoba oil, France smoke clothing Careless extract, methyl hydroxybenzoate, Nipasol mixing put into oil phase pot heating stirring to 85 degree as A phases, after stirring and dissolving is complete Heat preservation for standby use；
2) Sodium Hyaluronate, xanthans, glycerine, PEG-8 are mixed as B and is added to heating stirring in water phase pot To 85 degree, the completely rear heat preservation for standby use of stirring and dissolving；
3) emulsification pot is preheated to 60-65 degree, first be pumped into for B phases by 50 revs/min of mixing speed, then A phases are pumped into, and is stirred Mix 30 minutes, temperature is maintained at 85 degree；
4) C is added to emulsification pot, homogeneous 3 minutes, insulated and stirred 30 minutes, temperature is maintained at 80-85 degree, mixing speed 35 revs/min；The C phases are polyacrylamide/C13-14 isoparaffins/laureth -7；
5) being cooled to 42 degree adds D phases and E phases, insulated and stirred 10 minutes, 25-30 revs/min of mixing speed to be eventually adding F phases, are incubated 10-20 minutes；The D phases are polydimethyl siloxanes/polydimethy siloxanes alcohol, and the E phases are anti-aging group Compound, butanediol, the F phases are Bis(hydroxymethyl)imidazolidinyl urea；
6) stirring is cooled to 40 degree of dischargings.
Comparative example 1
It is that its anti-apolexis composition does not add the tinkling of pieces of jade extract that falls down to the ground with the difference of embodiment 1, other preparation conditions and method It is same as Example 1.
Comparative example 2
It is that its anti-apolexis composition does not add limonene extract with the difference of embodiment 1, other preparation conditions and method It is same as Example 1.
Comparative example 3
That its anti-apolexis composition does not add kudzu root extract with the difference of embodiment 1, other preparation conditions and method with Embodiment 1 is identical.
Comparative example 4
It is that its anti-apolexis composition does not add evening primrose oil with the difference of embodiment 1, other preparation conditions and method and reality Apply example 1 identical.
Performance of keeping humidity is tested
According to cosmetic composition moisture absorption, the gap of moisturizing, different NMFs are different to the active force of hydrone, absorb moisture It is different with the ability of moisture is kept.Oil has sealing process to moisture, can prevent scattering and disappearing for moisture.Big right of hygroscopic effect power Hydrone active force is strong, absorbs and keep the amount of moisture moisture loss also better than larger closure also few.Imitated using adhesive tape The biomaterials such as cuticula, cortex, are coated with cosmetics on adhesive tape, simulate the applicable cases of actual cosmetics.In constant temperature and humidity Under the conditions of a period of time after, weigh sample place before and after it is of poor quality, obtain the loss of sample, moisturizing ingredient can be calculated Moistening effect.
Experiment material
Some pieces of the clean glass plates of 7.5 × 7.5cm, 3M adhesive plasters, 50~500 μ l liquid-transfering guns, assay balance, potassium acetate [K2H3O2] saturated solution relative humidity about 60%, a ten thousandth balance.
Experimental technique and testing procedure
(1) 10 pieces of glass plate weight (M for posting 3M adhesive plasters are weighed0), record respectively, three pieces is blank, and three pieces are Sampling test
(2) 200 μ l sample drops are taken with liquid-transfering gun to be added on the glass plate for posting 3M adhesive plasters, the weight is weighed with assay balance M1(being accurate to 0.0001g), sample is uniformly distributed, and glass plate is put into the drier of the constant humidity of requirement, in triplicate. Remaining 3 pieces of blank glass plates are put into the drier of constant humidity together.
(3) after 4h, 8h is placed, glass plate is taken out, weighs the glass plate weight (M2), test its moisturizing rate and and relative Humidity ratio, is immediately placed into the drier of constant humidity after weighing.
(4) points for attention of this experiment are smeared as far as possible uniform during sample, it is impossible to have carry-over on applicator.By sample Product are taken out and weigh and be put into, and a drier is controlled within 15min, average one piece of glass plate 1min.Control time be by In sample, exposed to external environment, its moisture loss is very fast, can have a strong impact on test result.Glass plate is placed on immediately after taking out On the blank glass plate controlled in advance, also it is upside down in the container of balance during weighing.
(5) moisturizing rate computing formula：
Moisturizing rate=(M2-M0)/(M1-M0) × 100%
In formula：
M0：Hollow plate quality/g
M1：Glass sheet quality/g after sample-adding
M2：Quality/g after some hours is placed in drier
Test its appropriateness relatively for percent 60 when 4h and 8h moisturizing rate.
Referring to table 2 below, comparative example 3 is certain commercially available anti-aging face cream to experimental result
By table 2, the visible present invention has significant effect in terms of moisturizing.
Senile-resistant efficacy is verified
Experimental subjects：30 to 45 years old aspiration triers 200 are selected to be randomly divided into three groups, embodiment 1~5, comparative example 1~5 Every group of 20 people.
Test method：All volunteers carry out face cleaning treatment before sleeping every night, the anti-aging of group where everyone left face use Frost, right face is not used.It is on probation one month by a definite date, at the 7th day, the 15th day, respectively count a result on trial within the 30th day.Effectively represent It is tender white more flexible for trier or so face contrast facial lines are reduced, hence it is evident that desalination color spot；Invalid representation is trier's skin Texture is not any change；Generally trier's skin quality makes moderate progress but effect is not notable, between effective and invalid.Experiment Result see the table below 3
Table 3
The anti-aging face cream of embodiment 1~5 can be obtained by table three have and become apparent from more preferable anti-aging, whitening, bright color Effect.
Above example only illustrates embodiment of the present invention, does not there is any formal limitation to the present invention；Appoint What is engaged in professional and technical personnel, all has the ability to make some changes using the technology contents for disclosing or modifies, as equivalent The Equivalent embodiments of change, according to the technology of the present invention essence, simply modification, equivalent variations and modification are carried out to the present invention, are belonged to In the range of technical solution of the present invention.

Claims (7)

1. a kind of anti-apolexis composition, it is characterised in that the combination by following weight portion material composition：
Fall down to the ground 1-3 parts of tinkling of pieces of jade extract
Limonene 0.2-0.5 parts
Kudzu root extract 0.4-1.6 parts
Evening primrose oil 3-6 parts.
2. a kind of anti-apolexis composition according to claim 1, it is characterised in that the preparation side of the cardiospermum halicacabum extract Method is：
(1) dry cardiospermum halicacabum is ground into the cardiospermum halicacabum material powder that average grain diameter is 20~70 mesh；
(2) the cardiospermum halicacabum material powder obtained in step (1) is put into extraction vessel, to 15 times of addition in extraction vessel 75% ethanol solution, refluxing extraction 5 times, 2 hours every time, concentration obtained cardiospermum halicacabum extract after dry, pulverize.
3. a kind of anti-apolexis composition according to claim 1, it is characterised in that the preparation method of the kudzu root extract For：
(1) the fresh root of kudzu vine is taken, clean dry is ground into coarse grain, coarse grain water boiling and extraction 3 times, each 2h of decocting time merges Filtrate, stands 2h twice, and filtering, filtrate is standby；
(2) step (1) gained filtrate decompression is concentrated to give thick medicinal extract, thick medicinal extract is spray-dried (180 DEG C of inlet temperature, 70 DEG C of outlet temperature), dried medicinal extract is ground into the fine powder of 70 mesh sizes, obtain final product the kudzu root extract.
4. application of the anti-apolexis composition according to claim any one of 1-3 in cosmetics are prepared.
5. application according to claim 4, it is characterised in that the cosmetics are anti-aging face cream.
6. a kind of anti-aging face cream, it is characterised in that the face cream is made up of the raw material of following weight portion：
Anti-apolexis composition 4.6-11.1 parts as described in claim any one of 1-3；C14-22 alcohol/C12-20 alkyl glucosides 1.5-2 parts；Stearine/1.2-1.8 parts of PEG-100 stearates；Cetostearyl alcohol 1.8-2.2 parts；Saualane 2.5- 3.5 parts；Dimethyl silicone polymer 1-3 parts；Caprylic/capric triglyceride 2-4 parts；1-3 parts of Butyrospermum parkii fruit fat；Hydrogenation Jojoba It is oily 1-3 parts；0.2-0.8 parts of french lavender extract；Methyl hydroxybenzoate 0.1-0.2 parts；Nipasol 0.1-0.2 parts；Hyalomitome Sour sodium 0.01-0.04 parts；Xanthans 0.1-0.14 parts；Glycerine 1-4 parts；PEG-8 3-7 parts；Polyacrylamide/C13-14 Isoparaffin/laureth -70.2-0.6 parts；0.2-0.6 parts of polydimethyl siloxanes/polydimethy siloxanes alcohol；Fourth two Alcohol 1-2 parts；Bis(hydroxymethyl)imidazolidinyl urea 0.1-0.3 parts；Deionized water 35-70 parts.
7. a kind of preparation method of anti-aging face cream as claimed in claim 6, it is characterised in that the preparation method include with Lower step：
1) by C14-22 alcohol/C12-20 alkyl glucosides, stearine/PEG-100 stearates, cetostearyl alcohol, angle Shark alkane, dimethyl silicone polymer, caprylic/capric triglyceride, Butyrospermum parkii fruit fat, hydrogenated jojoba oil, french lavender are carried Take thing, methyl hydroxybenzoate, Nipasol mixing as A phases put into oil phase pot heating stirring to 85 degree, stirring and dissolving is incubated afterwards completely It is stand-by；
2) Sodium Hyaluronate, xanthans, glycerine, PEG-8, deionized water are mixed to be added in water phase pot as B and is heated Stir to 85 degree, the completely rear heat preservation for standby use of stirring and dissolving；
3) emulsification pot is preheated to 60-65 degree, first be pumped into for B phases by 50 revs/min of mixing speed, then A phases are pumped into, stirring 30 Minute, temperature is maintained at 85 degree；
4) C is added to emulsification pot, homogeneous 3 minutes, insulated and stirred 30 minutes, temperature is maintained at 80-85 degree, mixing speed 35 Rev/min；The C phases are polyacrylamide/C13-14 isoparaffins/laureth -7；
5) being cooled to 42 degree adds D phases and E phases, insulated and stirred 10 minutes, 25-30 revs/min of mixing speed to be eventually adding F phases, Insulation 10-20 minutes；The D phases be polydimethyl siloxanes/polydimethy siloxanes alcohol, the E phases be anti-apolexis composition, Butanediol, the F phases are Bis(hydroxymethyl)imidazolidinyl urea；
6) stirring is cooled to 40 degree of dischargings.
CN201710007079.4A 2017-01-04 2017-01-04 A kind of anti-apolexis composition and its application Withdrawn CN106727013A (en)

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CN107088176A (en) * 2017-06-08 2017-08-25 广州市花安堂生物科技有限公司 A kind of cosmetic material of blackcurrant seed oil
CN107411997A (en) * 2017-06-26 2017-12-01 上海新高姿化妆品有限公司 A kind of anti-aging face cream composition
CN109157456A (en) * 2018-10-27 2019-01-08 李素芬 A kind of skin maintenance essence cream and preparation method thereof
CN109394608A (en) * 2018-09-26 2019-03-01 李素芬 A kind of skin maintenance essence cream and preparation method thereof
CN111228184A (en) * 2020-03-26 2020-06-05 张虎 Moisturizing cosmetic composition and preparation method thereof

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CN105287310A (en) * 2015-12-01 2016-02-03 江苏隆力奇生物科技股份有限公司 Compound with wrinkle removing function and application of compound

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CN105267068A (en) * 2015-11-09 2016-01-27 贾芳兰 Evening primrose seed oil moisturizing cream and preparation method thereof
CN105287310A (en) * 2015-12-01 2016-02-03 江苏隆力奇生物科技股份有限公司 Compound with wrinkle removing function and application of compound

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CN107088176A (en) * 2017-06-08 2017-08-25 广州市花安堂生物科技有限公司 A kind of cosmetic material of blackcurrant seed oil
CN107411997A (en) * 2017-06-26 2017-12-01 上海新高姿化妆品有限公司 A kind of anti-aging face cream composition
CN107411997B (en) * 2017-06-26 2020-04-17 上海新高姿化妆品有限公司 Anti-aging face cream composition
CN109394608A (en) * 2018-09-26 2019-03-01 李素芬 A kind of skin maintenance essence cream and preparation method thereof
CN109157456A (en) * 2018-10-27 2019-01-08 李素芬 A kind of skin maintenance essence cream and preparation method thereof
CN111228184A (en) * 2020-03-26 2020-06-05 张虎 Moisturizing cosmetic composition and preparation method thereof

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