CN109394608A - A kind of skin maintenance essence cream and preparation method thereof - Google Patents

A kind of skin maintenance essence cream and preparation method thereof Download PDF

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Publication number
CN109394608A
CN109394608A CN201811122617.5A CN201811122617A CN109394608A CN 109394608 A CN109394608 A CN 109394608A CN 201811122617 A CN201811122617 A CN 201811122617A CN 109394608 A CN109394608 A CN 109394608A
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phase part
skin
phase
conditioning agent
parts
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李素芬
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

Abstract

The invention discloses a kind of skin maintenance essence cream and preparation method thereof, skin maintenance essence cream is partially made of A phase part, B phase part, C phase part, D phase part, E phase part, F phase part, G phase;A phase part is made of emulsifier, emollient, antioxidant, the first skin conditioning agent, the first preservative;B phase part is made of Second Skin conditioner, the first moisturizer, thickener, solvent;C phase part is made of pH adjusting agent and solvent;D phase part is made of the second moisturizer and third skin conditioning agent;E phase part is made of the 4th skin conditioning agent;F phase part is made of the 5th skin conditioning agent and solvent;G phase part is made of the second preservative and aromatic.This skin maintenance essence cream has maintenance damaged Stratum Corneum, improves brothers' decortication;Improve skin red capillary, promotes skin health;Deep moisturizing, anti-wrinkle enhance elasticity of skin;Improve skin eczema, repairs the function of baby buttocks diaper rash.

Description

A kind of skin maintenance essence cream and preparation method thereof
Technical field
The present invention relates to a kind of cosmetic fields more particularly to a kind of skin maintenance essence cream and preparation method thereof.
Background technique
With the influence of the factors such as weather, age, human skin lipid secretion is few, and natural moisturizing factor is few, body surface area Substantially moisture of skin lose increase and retain moisture function reduction, cause skin be easy it is dry, coarse, rubescent, itch, rise consider to be worth doing, Even rupture.Cosmetics are dazzling on the market, and consumer is difficult to choose the satisfied essence cream of a reparation skin, and existing Many essence cream skin care item contain certain toxic component, irritate skin, skin care cannot be not only achieved the effect that after use, is drawn instead Play various discomforts or even strong allergic reaction.
Summary of the invention
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide a kind of skin maintenance essence creams.This Skin maintenance essence cream has maintenance damaged Stratum Corneum, improves brothers' decortication;Improve skin red capillary, promotes skin health;It is deep Layer moisturizing, anti-wrinkle enhance elasticity of skin;Improve skin eczema, repairs the function of baby buttocks diaper rash.
The second object of the present invention is to provide a kind of preparation method of skin maintenance essence cream.The preparation method condition temperature It is simple, it can be achieved that industrialized production with preparation method.
An object of the present invention adopts the following technical scheme that realization: a kind of skin maintenance essence cream, by A phase part, B phase Partially, C phase part, D phase part, E phase part, F phase part, G phase part form;
The A phase part is made of emulsifier, emollient, antioxidant, the first skin conditioning agent, the first preservative;
The B phase part is made of Second Skin conditioner, the first moisturizer, thickener, solvent;
The C phase part is made of pH adjusting agent and solvent;
The D phase part is made of the second moisturizer and third skin conditioning agent;
The E phase part is made of the 4th skin conditioning agent;
The F phase part is made of the 5th skin conditioning agent and solvent;
The G phase part is made of the second preservative and aromatic.
Further, in A phase part, the emulsifier is that stearine, PEG-100 stearate, glycerol are hard One or more kinds of mixture in resin acid ester;The emollient be vaseline, Butyrospermum parkii fruit fatty oil, palm acid ethyl oneself The mixture of one or more of ester, dimethyl silicone polymer, cetostearyl alcohol, caprylic/capric triglyceride;It is described Antioxidant is tocopherol acetate;First skin conditioning agent is N- palmityl hydroxy-proline cetyl;Described first Preservative is the mixture of one or both of Nipasol, methyl hydroxybenzoate.
Further, in B phase part, the Second Skin conditioner be one of allantoin, creatine, niacinamide or Two or more mixtures;First moisturizer is the mixture of one or both of glycerol, propylene glycol;The thickener For the mixture of one or both of xanthan gum, carbomer;The solvent is water.
Further, in C phase part, the pH adjusting agent is arginine;The solvent is water.
Further, in D phase part, second moisturizer is dipropylene glycol, and the third skin conditioning agent is C12-13 alkyl glycerol base hydrolyzes Sodium Hyaluronate.
Further, in E phase part, the 4th skin conditioning agent is cardiospermum halicacabum flower/leaf/rattan extract.
Further, in F phase part, the 5th skin conditioning agent is madecassoside;The solvent is water.
Further, in G phase part, second preservative is Phenoxyethanol/Sensiva SC50;The aromatic For Pelargonium sunflower oil.
Further, the A phase part is grouped as by the group of following parts by weight meter: 2 parts of stearine/PEG- 100 stearates, 1.5 parts of stearines, 5~8 parts of vaselines, 3~5 parts of Butyrospermum parkii fruit fatty oils, 2~4 parts of palmitinic acid second The own ester of base, 1~3 part of dimethyl silicone polymer, 0.5~1 part of cetostearyl alcohol, 3~5 parts of caprylic/capric triglycerides, 0.5~1 Part tocopherol acetate, 0.5~1 part of N- palmityl hydroxy-proline cetyl, 0.08 part of Nipasol, 0.12 part of oxybenzene first Ester;
The B phase part is grouped as by the group of following parts by weight meter: 0.1~0.2 part of allantoin, 0.2~0.5 part of flesh Acid, 1~2 part of niacinamide, 8~12 parts of glycerol, 1~2 part of propylene glycol, 0.15~0.2 part of xanthan gum, 0.2~0.3 part of carbomer, 41.67~65.39 parts of water;
The C phase part is grouped as by the group of following parts by weight meter: 0.05~0.1 part of arginine, 1 part of water;
The D phase part is grouped as by the group of following parts by weight meter: 1~2 part of dipropylene glycol, 0.1~0.2 part of C12-13 Alkyl glycerol base hydrolyzes Sodium Hyaluronate;
The E phase part is grouped as by the group of following parts by weight meter: 1~2 part of cardiospermum halicacabum flower/leaf/rattan extract;
The F phase part is grouped as by the group of following parts by weight meter: 0.1~0.3 part of madecassoside, 3 parts of water;
The G phase part is grouped as by the group of following parts by weight meter: 0.5~0.8 part of Phenoxyethanol/ethylhexyl is sweet Oil, 0.01~0.03 portion of Pelargonium sunflower oil;
The sum of each component in above-mentioned A, B, C, D, E, F, G phase part is 100 parts.
The second object of the present invention adopts the following technical scheme that realization: a kind of preparation method of skin maintenance essence cream, packet Include following steps:
The step of preparing the phase part A: according to the emulsifier of formula ratio, emollient, antioxidant, the first skin conditioning agent, First preservative weighs, and each component weighed up is heated to 75-80 DEG C to completion dissolution;
The step of preparing the phase part B: claim according to the Second Skin conditioner of formula ratio, the first moisturizer, thickener, solvent It measures, each component weighed up is heated to 75-85 DEG C to completion dissolution;
The step of preparing the phase part C: in a solvent by the pH adjusting agent dissolution of formula ratio;
The step of preparing the phase part D: the second moisturizer of formula ratio and third skin conditioning agent are mixed;
The step of preparing the phase part F: in a solvent by the 5th skin conditioning agent dissolution of formula ratio;
The step of preparing the phase part G: the second preservative and aromatic of formula ratio are mixed;
The step of emulsification: being partially drawn into emulsion pot for B phase, then A phase be partially heated to 78 DEG C, be then pumped into emulsion pot, Homogeneous 3-8 minutes, keep the temperature 10-20 minutes;
The step of stirring: slowing down stirring, and mixing speed 250-300r/min is cooled to 50 DEG C, while C phase part being added Enter to stir evenly;
The step of D, E, F, G phase part is added: temperature is down to 38-42 DEG C, and it is equal that D, E, F, G phase are partially sequentially added to stirring It is even;
The step of discharging: temperature is down to 38 DEG C, and 200 mesh filtering, discharging dispenses after the assay was approved.
Compared with prior art, the beneficial effects of the present invention are:
1. it is preferable to improve brothers' exfoliant effect for maintenance damaged Stratum Corneum;
2. improving skin red capillary, promote skin health;
3. deep moisturizing, anti-wrinkle enhances elasticity of skin;
4. improving skin eczema, it is preferable to repair baby buttocks diaper rash effect.
Specific embodiment
In the present invention, if not refering in particular to, all parts, percentage are unit of weight, used equipment and raw material etc. It is commercially available or commonly used in the art.Method in following embodiments is unless otherwise instructed the normal of this field Rule method.
A kind of skin maintenance essence cream, by A phase part, B phase part, C phase part, D phase partially, E phase partially, F phase partially, G phase part forms;
The A phase part is made of emulsifier, emollient, antioxidant, the first skin conditioning agent, the first preservative;
The B phase part is made of Second Skin conditioner, the first moisturizer, thickener, solvent;
The C phase part is made of pH adjusting agent and solvent;
The D phase part is made of the second moisturizer and third skin conditioning agent;
The E phase part is made of the 4th skin conditioning agent;
The F phase part is made of the 5th skin conditioning agent and solvent;
The G phase part is made of the second preservative and aromatic.
As further preferred scheme, in A phase part, the emulsifier is stearine, PEG-100 stearic acid One or more kinds of mixture in ester, stearine;The emollient is vaseline, Butyrospermum parkii fruit fatty oil, palm One or more of sour ethylhexyl, dimethyl silicone polymer, cetostearyl alcohol, caprylic/capric triglyceride are mixed Close object;The antioxidant is tocopherol acetate;First skin conditioning agent is N- palmityl hydroxy-proline cetyl; First preservative is the mixture of one or both of Nipasol, methyl hydroxybenzoate.
As further preferred scheme, in B phase part, the Second Skin conditioner is allantoin, creatine, niacinamide One or more of mixture;First moisturizer is the mixture of one or both of glycerol, propylene glycol; The thickener is the mixture of one or both of xanthan gum, carbomer;The solvent is water.
As further preferred scheme, in C phase part, the pH adjusting agent is arginine;The solvent is water.
As further preferred scheme, in D phase part, second moisturizer is dipropylene glycol, the third skin Conditioner is that C12-13 alkyl glycerol base hydrolyzes Sodium Hyaluronate.
As further preferred scheme, in E phase part, the 4th skin conditioning agent is that cardiospermum halicacabum flower/leaf/rattan mentions Take object.
As further preferred scheme, in F phase part, the 5th skin conditioning agent is madecassoside;It is described Solvent is water.
As further preferred scheme, in G phase part, second preservative is Phenoxyethanol/Sensiva SC50; The aromatic is Pelargonium sunflower oil.
As further preferred scheme, the A phase part is grouped as by the group of following parts by weight meter: 2 parts of glyceryl stearates Acid esters/PEG-100 stearate, 1.5 parts of stearines, 5~8 parts of vaselines, 3~5 parts of Butyrospermum parkii fruit fatty oils, 2~4 parts Ethylhexyl palmitate, 1~3 part of dimethyl silicone polymer, 0.5~1 part of cetostearyl alcohol, 3~5 parts of caprylic/capric glycerol three Ester, 0.5~1 part of tocopherol acetate, 0.5~1 part of N- palmityl hydroxy-proline cetyl, 0.08 part of Nipasol, 0.12 Part methyl hydroxybenzoate;
The B phase part is grouped as by the group of following parts by weight meter: 0.1~0.2 part of allantoin, 0.2~0.5 part of flesh Acid, 1~2 part of niacinamide, 8~12 parts of glycerol, 1~2 part of propylene glycol, 0.15~0.2 part of xanthan gum, 0.2~0.3 part of carbomer, 41.67~65.39 parts of water;
The C phase part is grouped as by the group of following parts by weight meter: 0.05~0.1 part of arginine, 1 part of water;
The D phase part is grouped as by the group of following parts by weight meter: 1~2 part of dipropylene glycol, 0.1~0.2 part of C12-13 Alkyl glycerol base hydrolyzes Sodium Hyaluronate;
The E phase part is grouped as by the group of following parts by weight meter: 1~2 part of cardiospermum halicacabum flower/leaf/rattan extract;
The F phase part is grouped as by the group of following parts by weight meter: 0.1~0.3 part of madecassoside, 3 parts of water;
The G phase part is grouped as by the group of following parts by weight meter: 0.5~0.8 part of Phenoxyethanol/ethylhexyl is sweet Oil, 0.01~0.03 portion of Pelargonium sunflower oil;
The sum of each component in above-mentioned A, B, C, D, E, F, G phase part is 100 parts.
C12-13 alkyl glycerol base hydrolysis Sodium Hyaluronate, hydroxyl product is added by the formula of improvement essence cream in the present invention Careless glucoside skin conditioning agent, cardiospermum halicacabum (CARDIOSPERMUM HALICACABUM) flower/leaf/boisiana extract are avenged, and adjusts each skin The dosage of skin conditioner improves brothers' decortication problem to reach maintenance damaged Stratum Corneum;Improve skin red capillary problem, promotes Skin health;Deep moisturizing, anti-wrinkle enhance elasticity of skin;Improve skin eczema, repairs baby buttocks diaper rash problem.
It wherein is connected with glycerol backbone and hydrophobic grouping on C12-13 alkyl glycerol base hydrolysis Sodium Hyaluronate, by hydrophily A part of hyaluronic acid is connect with hydrophobic grouping, it is made to act on skin barrier function, is a kind of repairing type hyaluronic acid.People Body skin is sheet layered structure, including from outer to inner includes keratinocyte layer, lipid layer, water layer, lipid layer, water layer, lipid Layer, keratinocyte layer.Lamellar structure, which can be, in healthy skin prevents moisture evaporation, is responsible for the barrier function of skin.? The barrier function that lamellar structure disorder will cause skin in withered skin can not play a role, and moisture evaporation accelerates, and cause skin It is withered.And C12-13 alkyl glycerol base hydrolyzes Sodium Hyaluronate (HyalorepairTM) lamellar structure of disorder is made to play connection water The connection function of layer and lipid layer enables the moisture-retaining capacity of the recovery of barrier function, skin to be promoted, to repair skin.
Skin sensitivity and the people for being easy to appear atopic dermatitis are easy to produce scytitis.Epidermis release inflammatory mediator is simultaneously located In inflammatory status.Blood vessel dilatation causes general red and fever symptom to occur.The hyper-proliferative of cell becomes skin than usual It is thicker.The disorder of skin internal organizational structure changes the external state of skin.Skin tarnish with it is clear.Serdex is earliest This plant of centella is introduced into and is applied in medical industry, and develops the purification technique of triterpenes molecule, is centella Effect source used in cosmetics and medicine adornment product.Madecassoside (MADECASSOSIDE) is for sensitive skin It and is one of main matter present in centella with the potent active constituent of releiving of psoriatic skin, having reduces skin Reactivity is releived (to anti-inflammatory aging), the effect of antipruritic-anti-erythema and improvement furfur, and can releive sensitive skin, specificity Dermatitis and psoriatic skin.
Cardiospermum halicacabum (CARDIOSPERMUM HALICACABUM) flower/leaf/boisiana extract is extracted from the graceful plant of tropical rattan and falls down to the ground The oil component of bell, for antipruritic and treatment allergic rash, phytosterol (β sterol, campesterol, beans steroid in homeotherapy Alcohol) inhibition of phospholipase A 2 and cyclooxygenase-2, reduce inflammation and allergic reaction.
The effect that above-mentioned skin conditioning agent is constructed and to form multiple moisturizing, repairs skin.
The preparation method of the skin maintenance essence cream, includes the following steps:
The step of preparing the phase part A: according to the emulsifier of formula ratio, emollient, antioxidant, the first skin conditioning agent, First preservative weighs, and each component weighed up is heated to 75-80 DEG C to completion dissolution;
The step of preparing the phase part B: claim according to the Second Skin conditioner of formula ratio, the first moisturizer, thickener, solvent It measures, each component weighed up is heated to 75-85 DEG C to completion dissolution;
The step of preparing the phase part C: in a solvent by the pH adjusting agent dissolution of formula ratio;
The step of preparing the phase part D: the second moisturizer of formula ratio and third skin conditioning agent are mixed;
The step of preparing the phase part F: in a solvent by the 5th skin conditioning agent dissolution of formula ratio;
The step of preparing the phase part G: the second preservative and aromatic of formula ratio are mixed;
The step of emulsification: being partially drawn into emulsion pot for B phase, then A phase be partially heated to 78 DEG C, be then pumped into emulsion pot, Homogeneous 3-8 minutes, keep the temperature 10-20 minutes;
The step of stirring: slowing down stirring, and mixing speed 250-300r/min is cooled to 50 DEG C, while C phase part being added Enter to stir evenly;
The step of D, E, F, G phase part is added: temperature is down to 38-42 DEG C, and it is equal that D, E, F, G phase are partially sequentially added to stirring It is even;
The step of discharging: temperature is down to 38 DEG C, and 200 mesh filtering, discharging dispenses after the assay was approved.
It is specific embodiment of the present invention below, used raw material, equipment etc. remove special limit in the following embodiments It can be obtained by buying pattern outside fixed.
Embodiment 1-3 skin maintenance essence cream
Skin maintenance essence cream is prepared according to the skin maintenance essence cream formula of the following table 1.
Table 1 is the formula of skin maintenance essence cream
The skin maintenance essence cream of embodiment 1-3 the preparation method is as follows:
The step of preparing the phase part A: according to the emulsifier of formula ratio, emollient, antioxidant, the first skin conditioning agent, First preservative weighs, and each component weighed up is heated to 78 DEG C to completion dissolution;
The step of preparing the phase part B: claim according to the Second Skin conditioner of formula ratio, the first moisturizer, thickener, solvent It measures, each component weighed up is heated to 80 DEG C to completion dissolution;
The step of preparing the phase part C: in a solvent by the pH adjusting agent dissolution of formula ratio;
The step of preparing the phase part D: the second moisturizer of formula ratio and third skin conditioning agent are mixed;
The step of preparing the phase part F: in a solvent by the 5th skin conditioning agent dissolution of formula ratio;
The step of preparing the phase part G: the second preservative and aromatic of formula ratio are mixed;
The step of emulsification: being partially drawn into emulsion pot for B phase, then A phase be partially heated to 78 DEG C, be then pumped into emulsion pot, Homogeneous 5 minutes, keep the temperature 15 minutes;
The step of stirring: slowing down stirring, and mixing speed 250-300r/min is cooled to 50 DEG C, while C phase part being added Enter to stir evenly;
The step of D, E, F, G phase part is added: temperature is down to 40 DEG C, and D, E, F, G phase are partially sequentially added and stirred evenly;
The step of discharging: temperature is down to 38 DEG C, and 200 mesh filtering, discharging dispenses after the assay was approved.
Effect assessment and performance detection
The performance of embodiment 1-3 is detected, detection project and result are for example following.
1, the test of damaged Stratum Corneum is repaired
Female volunteers of 15 ages between 18-50 years old are looked for, use the above skin maintenance essence cream in face respectively, Study subject uses once daily, is used continuously 30 days, and other any products are not used during test.After continuous use 30 days, The repairing effect of the damaged Stratum Corneum of its facial skin is measured, test method: using random, parallel control research, to above-mentioned production The damaged Stratum Corneum of product is repaired effect and is evaluated.Test obtained result such as the following table 2:
The test result of 2 embodiment 1-3 of table and the reparation damaged Stratum Corneum of comparative example
Sample Before use After 15 days After 30 days
Embodiment 1 Cuticula is thin, slight to peel Decortication situation has improvement Skin smooth
Embodiment 2 Cuticula is thin, slight to peel Decortication situation has improvement Skin smooth
Embodiment 3 Cuticula is thin, slight to peel Decortication situation has improvement Skin smooth
Commercially available common essence cream Cuticula is thin, slight to peel Improve unobvious Improve unobvious
From the above experimental result as can be seen, the present invention has obvious reparation damaged Stratum Corneum and improves the function slightly peeled Effect.
2, improve the test of skin red capillary
Female volunteers of 15 ages between 18-50 years old are looked for, use the above skin maintenance essence cream in face respectively, Study subject uses once daily, is used continuously 30 days, and other any products are not used during test.After continuous use 30 days, The improvement of the skin red capillary of its facial skin is measured, test method: using random, parallel control research, to above-mentioned production The skin red capillary of product improves effect and is evaluated.Test obtained result such as the following table 3:
The test result that the skin red capillary of 3 embodiment 1-3 of table and comparative example improves
Sample Before use After 15 days After 30 days
Embodiment 1 Face has red capillary It has clear improvement Skin health is not general red
Embodiment 2 Face has red capillary It has clear improvement Skin health is not general red
Embodiment 3 Face has red capillary It has clear improvement Skin health is not general red
Commercially available common essence cream Face has red capillary Have no improvement Improve unobvious
From the above experimental result as can be seen, the present invention has effects that be obviously improved skin red capillary.
3, the test of moistening effect
Female volunteers of 10 ages between 18~50 are looked for, in 20 DEG C, the indoor environment that 50 parts of relative humidity, point The fixed area for not drawing one 2 square centimeters in forehead uses the above skin maintenance essence cream and commercially available essence in fixed area Frost is tested with Corneometer CM285 skin moisture detector, and comprehensive to obtain humidity of skin delta data, test result is such as The following table 4:
The replenishing water and preserving moisture performance test of 4 embodiment 1-3 of table and comparative example
From the above experimental result as can be seen, the present invention is more obvious to skin moisturization.
4, improve the test of eczema effect
Baby volunteer with eczema of 15 ages between -1 year old 3 months is looked for, the above skin maintenance essence is applied Frost, study subject use once daily, are used continuously 7 days, and other any products are not used during test.After continuous use 7 days, The skin for observing eczema affected part improves situation, the result tested such as the following table 5:
The test result that the skin red capillary of 5 embodiment 1-3 of table and comparative example improves
Sample Before use After 7 days Cure rate part
Embodiment 1 There is slight erythema It has clear improvement 68%
Embodiment 2 There is slight erythema It has clear improvement 72%
Embodiment 3 There is slight erythema It has clear improvement 81%
From the above experimental result as can be seen, the present invention is more obvious to eczema effect is improved.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto, The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention Claimed range.

Claims (10)

1. a kind of skin maintenance essence cream, which is characterized in that by A phase part, B phase part, C phase part, D phase part, E phase portion Divide, F phase part, G phase part composition;
The A phase part is made of emulsifier, emollient, antioxidant, the first skin conditioning agent, the first preservative;
The B phase part is made of Second Skin conditioner, the first moisturizer, thickener, solvent;
The C phase part is made of pH adjusting agent and solvent;
The D phase part is made of the second moisturizer and third skin conditioning agent;
The E phase part is made of the 4th skin conditioning agent;
The F phase part is made of the 5th skin conditioning agent and solvent;
The G phase part is made of the second preservative and aromatic.
2. skin maintenance essence cream as described in claim 1, which is characterized in that in A phase part, the emulsifier is glycerol Stearate, PEG-100 stearate, mixture one or more kinds of in stearine;The emollient is mine Rouge, Butyrospermum parkii fruit fatty oil, ethylhexyl palmitate, dimethyl silicone polymer, cetostearyl alcohol, caprylic/capric triglyceride One or more of mixture;The antioxidant is tocopherol acetate;First skin conditioning agent is N- Palmityl hydroxy-proline cetyl;First preservative is the mixing of one or both of Nipasol, methyl hydroxybenzoate Object.
3. skin maintenance essence cream as described in claim 1, which is characterized in that in B phase part, the Second Skin conditioning Agent is the mixture of one or more of allantoin, creatine, niacinamide;First moisturizer is glycerol, propylene glycol One or both of mixture;The thickener is the mixture of one or both of xanthan gum, carbomer;It is described molten Agent is water.
4. skin maintenance essence cream as described in claim 1, which is characterized in that in C phase part, the pH adjusting agent is essence Propylhomoserin;The solvent is water.
5. skin maintenance essence cream as described in claim 1, which is characterized in that in D phase part, second moisturizer is Dipropylene glycol, the third skin conditioning agent are that C12-13 alkyl glycerol base hydrolyzes Sodium Hyaluronate.
6. skin maintenance essence cream as described in claim 1, which is characterized in that in E phase part, the 4th skin condition Agent is cardiospermum halicacabum flower/leaf/rattan extract.
7. skin maintenance essence cream as described in claim 1, which is characterized in that in F phase part, the 5th skin condition Agent is madecassoside;The solvent is water.
8. skin maintenance essence cream as described in claim 1, which is characterized in that in G phase part, second preservative is Phenoxyethanol/Sensiva SC50;The aromatic is Pelargonium sunflower oil.
9. skin maintenance essence cream as described in claim 1, which is characterized in that the A phase part is by following parts by weight meter Group be grouped as: 2 parts of stearines/PEG-100 stearate, 1.5 parts of stearines, 5~8 parts of vaselines, 3~5 Part Butyrospermum parkii fruit fatty oil, 2~4 parts of ethylhexyl palmitate, 1~3 part of dimethyl silicone polymer, 0.5~1 part of cetearyl alcohol Alcohol, 3~5 parts of caprylic/capric triglycerides, 0.5~1 part of tocopherol acetate, 0.5~1 part of N- palmityl hydroxy-proline whale Wax ester, 0.08 part of Nipasol, 0.12 part of methyl hydroxybenzoate;
B phase part is grouped as by the group of following parts by weight meter: 0.1~0.2 part of allantoin, 0.2~0.5 part of creatine, 1~ 2 parts of niacinamide, 8~12 parts of glycerol, 1~2 part of propylene glycol, 0.15~0.2 part of xanthan gum, 0.2~0.3 part of carbomer, 41.67~ 65.39 part water;
The C phase part is grouped as by the group of following parts by weight meter: 0.05~0.1 part of arginine, 1 part of water;
The D phase part is grouped as by the group of following parts by weight meter: 1~2 part of dipropylene glycol, 0.1~0.2 part of C12-13 alkyl Glyceryl hydrolyzes Sodium Hyaluronate;
The E phase part is grouped as by the group of following parts by weight meter: 1~2 part of cardiospermum halicacabum flower/leaf/rattan extract;
The F phase part is grouped as by the group of following parts by weight meter: 0.1~0.3 part of madecassoside, 3 parts of water;
The G phase part is grouped as by the group of following parts by weight meter: 0.5~0.8 part of Phenoxyethanol/Sensiva SC50, 0.01~0.03 portion of Pelargonium sunflower oil;
The sum of each component in above-mentioned A, B, C, D, E, F, G phase part is 100 parts.
10. a kind of preparation method of skin maintenance essence cream, which comprises the steps of:
The step of preparing the phase part A: according to the emulsifier of formula ratio, emollient, antioxidant, the first skin conditioning agent, first Preservative weighs, and each component weighed up is heated to 75-80 DEG C to completion dissolution;
The step of preparing the phase part B: it is weighed according to the Second Skin conditioner of formula ratio, the first moisturizer, thickener, solvent It is good, each component weighed up is heated to 75-85 DEG C to completion dissolution;
The step of preparing the phase part C: in a solvent by the pH adjusting agent dissolution of formula ratio;
The step of preparing the phase part D: the second moisturizer of formula ratio and third skin conditioning agent are mixed;
The step of preparing the phase part F: in a solvent by the 5th skin conditioning agent dissolution of formula ratio;
The step of preparing the phase part G: the second preservative and aromatic of formula ratio are mixed;
The step of emulsification: B phase is partially drawn into emulsion pot, then A phase is partially heated to 78 DEG C, is then pumped into emulsion pot, homogeneous 3-8 minutes, keep the temperature 10-20 minutes;
The step of stirring: slowing down stirring, and mixing speed 250-300r/min is cooled to 50 DEG C, while C phase part being added and is stirred It mixes uniformly;
The step of D, E, F, G phase part is added: temperature is down to 38-42 DEG C, and D, E, F, G phase are partially sequentially added and stirred evenly;
The step of discharging: temperature is down to 38 DEG C, and 200 mesh filtering, discharging dispenses after the assay was approved.
CN201811122617.5A 2018-09-26 2018-09-26 A kind of skin maintenance essence cream and preparation method thereof Pending CN109394608A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109966231A (en) * 2019-04-11 2019-07-05 冯江 A kind of bright face skin beautifying cream and preparation method thereof
CN110522712A (en) * 2019-05-27 2019-12-03 广州好蝶化妆品有限公司 A kind of bad face maintenance essence and preparation method
CN111150700A (en) * 2020-03-11 2020-05-15 广州市逸轩精细化工有限公司 Hormone face-repairing essence cream and preparation method thereof
CN112891286A (en) * 2021-02-25 2021-06-04 深圳市珍妮肤化妆品有限公司 Beautifying and firming repair cream and preparation method thereof
CN113491662A (en) * 2021-08-06 2021-10-12 广州天源生物科技有限公司 Essence cream for repairing skin and preparation method thereof

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CN106727013A (en) * 2017-01-04 2017-05-31 广州聚澜健康产业研究院有限公司 A kind of anti-apolexis composition and its application
CN107468561A (en) * 2017-08-01 2017-12-15 广东润洁日化有限公司 A kind of natural and multi-functional cream and its preparation
CN108113902A (en) * 2018-01-11 2018-06-05 广州雪雅化妆品有限公司 A kind of essence cream

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CN106333885A (en) * 2016-08-25 2017-01-18 广州睿森生物科技有限公司 Plant extract and eye essence liquid
CN106727013A (en) * 2017-01-04 2017-05-31 广州聚澜健康产业研究院有限公司 A kind of anti-apolexis composition and its application
CN107468561A (en) * 2017-08-01 2017-12-15 广东润洁日化有限公司 A kind of natural and multi-functional cream and its preparation
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109966231A (en) * 2019-04-11 2019-07-05 冯江 A kind of bright face skin beautifying cream and preparation method thereof
CN110522712A (en) * 2019-05-27 2019-12-03 广州好蝶化妆品有限公司 A kind of bad face maintenance essence and preparation method
CN111150700A (en) * 2020-03-11 2020-05-15 广州市逸轩精细化工有限公司 Hormone face-repairing essence cream and preparation method thereof
CN112891286A (en) * 2021-02-25 2021-06-04 深圳市珍妮肤化妆品有限公司 Beautifying and firming repair cream and preparation method thereof
CN113491662A (en) * 2021-08-06 2021-10-12 广州天源生物科技有限公司 Essence cream for repairing skin and preparation method thereof

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