CN107007499A - A kind of emulsion with moisturizing anti-radiation effect - Google Patents
A kind of emulsion with moisturizing anti-radiation effect Download PDFInfo
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- CN107007499A CN107007499A CN201710190176.1A CN201710190176A CN107007499A CN 107007499 A CN107007499 A CN 107007499A CN 201710190176 A CN201710190176 A CN 201710190176A CN 107007499 A CN107007499 A CN 107007499A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
Abstract
The invention discloses a kind of emulsion with moisturizing anti-radiation effect, mainly constituted including compositions such as ginkgo biloba p.e, evening primrose oil, Tea Polyphenols, aloe barbadensis Miller polysaccharide, glycerine, skin conditioners.Pure natural composition with anti-radiation effect is used as main active using ginkgo biloba p.e, evening primrose oil, Tea Polyphenols and aloe barbadensis Miller polysaccharide; and compound by a certain percentage; products obtained therefrom not only can effective Ultraviolet radiation absorbing; function of immune system, enhancing Antioxidant Enzyme Systems, the generation for reducing free radical and the effect for keeping skin wet can also be protected; it can effectively prevent and reduce infringement of the radiation to skin; the self-protection ability of skin is improved, makes skin water profit fine and smooth；The emulsion of the present invention is not stimulated gently, safe, effect significantly, maintenance one can make that skin and muscles are fair, water moistens and high resilience.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of emulsion with moisturizing anti-radiation effect.
Background technology
Used with the development of science and technology, the electronic product such as computer and mobile phone has become indispensable life in people's life
Product, also give people to bring various infringements, particularly electromagnetic radiation to the skin of people while these electronic products give people to bring convenience
Skin causes very big injury.There are some researches show electromagnetic radiation can induce generation free radical, increase the interior free-radical contents of human body
It is many.Two free radicals can have certain infringement to skin, be mainly shown as：(1) serum antiprotease in skin is made to lose activity；
(2) Skin Cell film is destroyed (3) injured skin gene causes appearance and the savings of cytometaplasia.What if cell membrane was destroyed
Speed is more than cytothesis speed, and function of organization will be affected and change, and cause lesion etc.；Occur in subcutaneous collagen group
Knit, skin can be made to follow the string.If human body is long-term by such injury, caused result is exactly various chronic diseases and people
The aging of body, so as to cause color spot, inflammation, accelerate skin aging, destruction immune system and DNA destructions etc..In addition, solar radiation
Also skin aging can be accelerated, make skin the phenomenons such as dark yellow, color spot, wrinkle, pore be thick occur.Radiation is ubiquitous, can be rated as " hidden
Shape killer ", so a safe and efficient radiation protection product of research and development is necessary.
In existent technique, the research that radiation protection product is largely also rested on cloth and some special materials, and
It is relatively fewer in the research of skin type, and also the good and bad jumbled together for radiation proof skin type product, effect differs.Using radiation proof concept to sell
The product of point, the actual but product without anti-radiation effect spreads unchecked, and either effect is not obvious or adds rapid whitening composition,
Or anti-corrosion body is excessive, excitant is big.
The content of the invention
In view of the above-mentioned problems, it is an object of the invention to provide a kind of emulsion with moisturizing anti-radiation effect.
Technical scheme is as follows：
A kind of emulsion with moisturizing anti-radiation effect mainly includes following plant composition：Ginkgo biloba p.e, the moon are shown in
Careless oil, Tea Polyphenols, aloe barbadensis Miller polysaccharide, the parts by weight of wherein each component are：0.1-2 parts of ginkgo biloba p.e, evening primrose oil
0.1-5 parts, 0.1-1.2 parts of Tea Polyphenols, 0.2-1.5 parts of aloe barbadensis Miller polysaccharide.
Preferably, each Parts by Ingredients of the plant composition is：0.5-1.5 parts of ginkgo biloba p.e, evening primrose oil
1-3 parts, 0.5-1 parts of Tea Polyphenols, 0.5-1.2 parts of aloe barbadensis Miller polysaccharide.
The preparation method of the ginkgo biloba p.e is as follows：Fresh ginkgo leaf is taken, by 1:Solid-liquid ratio (the g/ of (10-15)
Ml) ginkgo leaf is immersed to concentration 65-85% alcohol solution dipping 60-90min；Feed liquid is placed in water-bath and is heated to reflux
1.5-3h is extracted, filtrate is collected in filtering, and filter residue repeats to extract once with 8 times of amount 75-85% ethanol, merges filtrate twice；Will filter
Liquid is concentrated under reduced pressure into no alcohol taste, and concentrate is adsorbed by AB-8 macroporous resin columns, first with distillation water elution, then uses 60% second
Alcohol is eluted, and collects 60% ethanol eluate, the ginkgo biloba p.e is obtained after being concentrated under reduced pressure.
The emulsion is consisted of the following composition：Plant composition 0.30-6.00%, skin conditioner 5.00-15.00%,
Emulsifying agent 2.00-7.00%, glycerine 6.00-8.00%, OXYBENZONE 1.00-2.00%, allantoin 0.30-0.50%, essence
0.10-0.30%, preservative 0.01-0.80%, hydroxyethyl cellulose 0.05-0.10%, deionized water surplus.
The emulsifying agent is stearine, methyl sesquistearate, PEG-20 methyl times semi-solid fats
At least one of the smooth stearate of acid esters, sorb, the dimerization hydroxy stearic acid ester of polyglycereol -2.
The skin conditioner be stearic acid, stearyl alcohol, isopropyl myristate, octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester in extremely
Few one kind.
The preservative is at least one of butyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, Phenoxyethanol.
The present invention also provides a kind of preparation method of the emulsion with moisturizing anti-radiation effect, comprises the following steps：By breast
Agent, skin conditioner, surfactant, OXYBENZONE mixing put into oil phase pot heating stirring to 85 degree as A phases, stir molten
The completely rear heat preservation for standby use of solution；Using glycerine, allantoin, deionized water mix as B be added to aqueous phase pot in heating stirring to 85 degree,
The completely rear heat preservation for standby use of stirring and dissolving；Emulsification pot is preheated to 60-65 degree, B phases are first pumped into by 50 revs/min of mixing speed, then
A phases are pumped into, stirred 30 minutes, temperature is maintained at 85 degree；C is added to emulsification pot, homogeneous 3 minutes, insulated and stirred 30 minutes,
Temperature is maintained at 80-85 degree, 35 revs/min of mixing speed；The C phases are hydroxyethyl cellulose；42 degree of addition D phases are cooled to,
Insulated and stirred 10 minutes, 25-30 revs/min of mixing speed is eventually adding E phases, is incubated 10-20 minutes；The D phases are plant group
Compound, the E phases are preservative；Stirring is cooled to 40 degree of dischargings.
Described ginkgo biloba p.e contains abundant flavone compound and terpene lactones compound, with good anti-
Radiation and anti-aging effects.Its mechanism of action includes：(1) lymphocyte transformation ability is improved, radiation is reduced to immune system
Damage；(2) protection red blood cell and hemoglobin, suppress the reduction of red blood cell and hemoglobin caused by radiation；(3) paddy Guang is improved
Sweet peptide peroxidase, superoxide dismutase activity, reduce mda content, so that recover the Scavenging activity of oxygen radical,
Reduce MDA formation, protection membrane structure and function it is complete.
Described evening primrose oil is squeezed from the seed of oenothera biennis, many containing linoleic acid, oleic acid, palmitic acid, leukotrienes etc.
Unrighted acid kind needed by human and vitamin and mineral etc., with anti-inflammatory, anti-oxidant, antithrombotic, lipid-loweringing, hypoglycemic,
The effect such as fat-reducing.Research shows that Tea Polyphenols can significantly reduce the peroxide value and acid number of evening primrose oil, have good to evening primrose oil
Good anti-photosensitized oxidation and anti-ultrasonic radiation effect.
Described Tea Polyphenols comes from natural green tea, can absorb 200~400nm ultraviolet, be a class high-efficiency low-toxicity
Natural, with bioactivity such as anti-oxidant, elimination free radicals.The oxidation-reduction potential of Tea Polyphenols is very low, possesses many
Individual phenolic hydroxyl group, using the teaching of the invention it is possible to provide proton is combined to eliminate the free radical of internal excess with the free radical that radiation is produced, it is to avoid biological big
The damage of molecule, so as to play a protective role.Meanwhile, Tea Polyphenols can strengthen glutathione peroxidase, catalase, fat also
The activity of protoenzyme and glutathione-s- transferases, removing energy of enhancing body itself Antioxidative Defense System to excessive free radicals
Power.Tea Polyphenols can also effectively suppress tyrosinase activity, reduce the formation of melanin, have effects that Whitening, spot.
Described aloe barbadensis Miller polysaccharide has good moisture-keeping function, is excellent natural moisture preserving agent, its mechanism of action
Including：(1) hydroxyl, carboxyl and other polar groups in polysaccharide molecule can be with hydrone formation hydrogen bond with reference to substantial amounts of water
Point；(2) in extracellular matrix, polysaccharide is collectively constituted containing large quantity of moisture with other polysaccharide components and fibrous proteins in skin
Extracellular gelatinised matrix, provide moisture for skin；(3) polysaccharide has film forming, can form one layer of water conservation film in skin surface,
The evaporation of moisture outwardly is reduced, the further aquation of cuticula is induced, moisturizing moisture-keeping function is completed.Therefore, the strong absorption of polysaccharide
Property and good film forming be effectively combined, provide effective guarantee for skin moisture-keeping.Secondly, aloe polysaccharide also has antioxygen
Change, promote wound healing and strengthen the effect of skin elasticity.
Compared with prior art, the device have the advantages that as follows：(1) present invention has the pure day of anti-radiation effect
Right composition presses one using ginkgo biloba p.e, evening primrose oil, Tea Polyphenols and aloe barbadensis Miller polysaccharide as main active
Certainty ratio is compounded, products obtained therefrom not only can effective Ultraviolet radiation absorbing, function of immune system, enhancing can also be protected anti-oxidant
System enzymatic activity, the generation for reducing free radical and the effect for keeping skin wet, can effectively prevent and reduce radiation to skin
Infringement, improves the self-protection ability of skin, makes skin water profit fine and smooth；(2) the polyphenol hydroxyl for the Tea Polyphenols that composition is added
The polyhydroxy and lactone bond of base and ginkgolides are simultaneously deposited, and cooperate with Antiradiation injury；Tea Polyphenols can also significantly reduce oenothera biennis
The peroxide value and acid number of oil, have good anti-photosensitized oxidation and anti-ultrasonic radiation to act on to evening primrose oil.Compatibility is good, makes group
Compound Synergistic, can be obviously improved the anti-radiation effect of product；(3) excellent sweet of aloe barbadensis Miller polysaccharide combination water lock moisturizing
Oil, further enhances the moisture-keeping efficacy of the present invention, adds the synergy of skin conditioner so that emulsion of the invention has aobvious
The skin care effect of work, maintenance one can make that skin and muscles are fair, water moistens and high resilience；(4) emulsion of the invention do not stimulate gently,
Safe, effect is notable；, can large-scale promotion and its preparation method is simple.
Embodiment
The present invention is further elaborated by the following specific embodiment
The following component title occurred in text is INCI (Internation Nomenclaure Cosmetic
Ingredent, i.e. international cosmetic raw material name) institute to defined title：Octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester.
Embodiment 1
Plant composition：1 part of ginkgo biloba p.e, 1 part of evening primrose oil, 1 part of Tea Polyphenols, 2 parts of aloe barbadensis Miller polysaccharide, 1
Part is set to 100g；Ginkgo biloba p.e 100g, evening primrose oil 100g, Tea Polyphenols 100g, aloe barbadensis Miller polysaccharide 200g；Ginkgo leaf
Extract, evening primrose oil, the mass ratio of Tea Polyphenols and aloe barbadensis Miller polysaccharide are 1:1:1:2.
Embodiment 2
Plant composition：20 parts of ginkgo biloba p.e, 50 parts of evening primrose oil, 12 parts of Tea Polyphenols, aloe barbadensis Miller polysaccharide 15
Part, 1 part is set to 10g；Ginkgo biloba p.e 200g, evening primrose oil 500g, Tea Polyphenols 120g, aloe barbadensis Miller polysaccharide 150g；Silver
Apricot leaf extract, evening primrose oil, the mass ratio of Tea Polyphenols and aloe barbadensis Miller polysaccharide are 20:50:12:15.
Embodiment 3
Plant composition：1 part of ginkgo biloba p.e, 2 parts of evening primrose oil, 1 part of Tea Polyphenols, 1 part of aloe barbadensis Miller polysaccharide, 1
Part is set to 100g；Ginkgo biloba p.e 100g, evening primrose oil 200g, Tea Polyphenols 100g, aloe barbadensis Miller polysaccharide 100g；Ginkgo leaf
Extract, evening primrose oil, the mass ratio of Tea Polyphenols and aloe barbadensis Miller polysaccharide are 1:2:1:1.
Embodiment 4
Plant composition：15 parts of ginkgo biloba p.e, 30 parts of evening primrose oil, 10 parts of Tea Polyphenols, aloe barbadensis Miller polysaccharide 12
Part, 1 part is set to 10g；Ginkgo biloba p.e 150g, evening primrose oil 300g, Tea Polyphenols 100g, aloe barbadensis Miller polysaccharide 120g；Silver
Apricot leaf extract, evening primrose oil, the mass ratio of Tea Polyphenols and aloe barbadensis Miller polysaccharide are 15:30:10:12.
The preparation method of ginkgo biloba p.e is as follows in embodiment 1~4：Fresh ginkgo leaf is taken, by 1:The material of (10-15)
Liquor ratio (g/ml) immerses the ginkgo leaf concentration 65-85% alcohol solution dipping 60-90min；Feed liquid is placed in water-bath
Filtrate is collected in heating and refluxing extraction 1.5-3h, filtering, and filter residue is repeated to extract once, merged twice with 8 times of amount 75-85% ethanol
Filtrate；No alcohol taste is concentrated filtrate to, concentrate is adsorbed by AB-8 macroporous resin columns, first with distillation water elution,
60% ethanol elution is used again, collects 60% ethanol eluate, the ginkgo biloba p.e is obtained after being concentrated under reduced pressure.
It is embodiment that there are embodiment 5~9 emulsion formulations of moisturizing anti-radiation effect, which to be shown in Table plant composition in one, table one,
Made plant composition
Table one
The preparation method following steps of the emulsion of embodiment 5~9：By stearine, methyl sesquistearate,
PEG-20 methyls sesquistearate, the smooth stearate of sorb, the dimerization hydroxy stearic acid ester of polyglycereol -2 are stearic acid, hard
Lipidol, isopropyl myristate, octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester, OXYBENZONE mixing put into oil phase pot heating stirring extremely as A phases
85 degree, the completely rear heat preservation for standby use of stirring and dissolving；Glycerine, allantoin, deionized water are mixed to be added in aqueous phase pot as B and heated
Stirring is to 85 degree, heat preservation for standby use after stirring and dissolving is complete；Emulsification pot is preheated to 60 degree, 50 revs/min of mixing speed, first by B
Mutually it is pumped into, then A phases is pumped into, stirs 30 minutes, temperature is maintained at 85 degree；C is added to emulsification pot, homogeneous 3 minutes, insulation is stirred
Mix 30 minutes, temperature is maintained at 80 degree, 35 revs/min of mixing speed；The C phases are hydroxyethyl cellulose；42 degree are cooled to add
Enter D phases, insulated and stirred 10 minutes, 25 revs/min of mixing speed is eventually adding E phases, is incubated 10 minutes；The D phases are plant group
Compound, the E phases are preservative；Stirring is cooled to 40 degree of dischargings.
It is implementation that there are embodiment 10~14 emulsion formulations of moisturizing anti-radiation effect, which to be shown in Table plant composition in two, table two,
The made plant composition of example 2
Table two
The preparation method of the emulsion of embodiment 10~14 comprises the following steps：By stearine, methyl times semihard
Resin acid ester, PEG-20 methyls sesquistearate, the smooth stearate of sorb, the dimerization hydroxy stearic acid ester of polyglycereol -2, firmly
Resin acid, stearyl alcohol, isopropyl myristate, octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester, OXYBENZONE mixing put into oil phase pot as A phases and added
Thermal agitation is to 85 degree, heat preservation for standby use after stirring and dissolving is complete；Glycerine, allantoin, deionized water are mixed as B and are added to aqueous phase
Heating stirring is to 85 degree in pot, heat preservation for standby use after stirring and dissolving is complete；Emulsification pot is preheated to 65 degree, 50 revs/min of mixing speed
B phases, are first pumped into by clock, then A phases are pumped into, and are stirred 30 minutes, temperature is maintained at 85 degree；C is added to emulsification pot, 3 points of homogeneous
Clock, insulated and stirred 30 minutes, temperature is maintained at 85 degree, 35 revs/min of mixing speed；The C phases are hydroxyethyl cellulose；Cooling
To 42 degree of addition D phases, insulated and stirred 10 minutes, 30 revs/min of mixing speed is eventually adding E phases, is incubated 15 minutes；The D phases
For plant composition, the E phases are butyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, Phenoxyethanol；Stirring is cooled to 40
Degree discharging.
It is implementation that there are embodiment 15~19 emulsion formulations of moisturizing anti-radiation effect, which to be shown in Table plant composition in three, table three,
The made plant composition of example 3
Table three
The preparation method of the emulsion of embodiment 15~19 comprises the following steps：By stearine, methyl times semihard
Resin acid ester, PEG-20 methyls sesquistearate, the smooth stearate of sorb, the dimerization hydroxy stearic acid ester of polyglycereol -2, firmly
Resin acid, stearyl alcohol, isopropyl myristate, octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester, OXYBENZONE mixing put into oil phase pot as A phases and added
Thermal agitation is to 85 degree, heat preservation for standby use after stirring and dissolving is complete；Glycerine, allantoin, deionized water are mixed as B and are added to aqueous phase
Heating stirring is to 85 degree in pot, heat preservation for standby use after stirring and dissolving is complete；Emulsification pot is preheated to 65 degree, 50 revs/min of mixing speed
B phases, are first pumped into by clock, then A phases are pumped into, and are stirred 30 minutes, temperature is maintained at 85 degree；C is added to emulsification pot, 3 points of homogeneous
Clock, insulated and stirred 30 minutes, temperature is maintained at 85 degree, 35 revs/min of mixing speed；The C phases are hydroxyethyl cellulose；Cooling
To 42 degree of addition D phases, insulated and stirred 10 minutes, 30 revs/min of mixing speed is eventually adding E phases, is incubated 20 minutes；The D phases
For plant composition, the E phases are butyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, Phenoxyethanol；Stirring is cooled to 40
Degree discharging.
It is implementation that there are embodiment 20~24 emulsion formulations of moisturizing anti-radiation effect, which to be shown in Table plant composition in four, table three,
The made plant composition of example 4
Table four
The preparation method of the emulsion of embodiment 15~19 comprises the following steps：By stearine, methyl times semihard
Resin acid ester, PEG-20 methyls sesquistearate, the smooth stearate of sorb, the dimerization hydroxy stearic acid ester of polyglycereol -2, firmly
Resin acid, stearyl alcohol, isopropyl myristate, octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester, OXYBENZONE mixing put into oil phase pot as A phases and added
Thermal agitation is to 85 degree, heat preservation for standby use after stirring and dissolving is complete；Glycerine, allantoin, deionized water are mixed as B and are added to aqueous phase
Heating stirring is to 85 degree in pot, heat preservation for standby use after stirring and dissolving is complete；Emulsification pot is preheated to 60 degree, 50 revs/min of mixing speed
B phases, are first pumped into by clock, then A phases are pumped into, and are stirred 30 minutes, temperature is maintained at 85 degree；C is added to emulsification pot, 3 points of homogeneous
Clock, insulated and stirred 30 minutes, temperature is maintained at 80 degree, 35 revs/min of mixing speed；The C phases are hydroxyethyl cellulose；Cooling
To 42 degree of addition D phases, insulated and stirred 10 minutes, 25 revs/min of mixing speed is eventually adding E phases, is incubated 20 minutes；The D phases
For plant composition, the E phases are butyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, Phenoxyethanol；Stirring is cooled to 40
Degree discharging.
Comparative example 1
Difference with embodiment 5 is not add ginkgo biloba p.e, and other preparation conditions and method are same as Example 5.
Comparative example 2
Difference with embodiment 5 is not add evening primrose oil, and other preparation conditions and method are same as Example 5.
Comparative example 3
Difference with embodiment 5 is not add Tea Polyphenols, and other preparation conditions and method are same as Example 5.
Comparative example 4
Difference with embodiment 5 is not add aloe barbadensis Miller polysaccharide, other preparation conditions and method and the phase of embodiment 5
Together.
Comparative example 5
Difference with embodiment 5 is not add plant composition, and other preparation conditions and method are same as Example 5.
Comparative example 6
Difference with embodiment 5 is that the percentage by weight of plant composition is 0.2%, other preparation conditions and method and reality
Apply example 5 identical.
Comparative example 7
Difference with embodiment 5 is that the percentage by weight of plant composition is 6.1%, other preparation conditions and method and reality
Apply example 5 identical.
Moisturizing efficacy validation
Experimental subjects：Choose the mouse of 280 12 to 13 week old.
Test method：All mouse are shaved off into back dorsal body setae with shaver, about 2cm × 3cm skin are exposed, then
28 groups are randomly divided into, butanediol solution is as blank control, and 28 components are embodiment 5~24, comparative example 1~7 and control group.
Each group emulsion is applied to the baring skin of mouse, control group smears butanediol, then mouse is placed under dehumidifier environment and carried out
Exposure, exposure 6 hours, continue 15 days daily：Then mouse back baring skin moisture determination is carried out, removes de- with card punch
Skin histology 0.5g after hair, precision claims skin weight in wet base, is put into 48h in 80 DEG C of drying boxes, claims skin dry weight.And surveyed by following equation
Measure the skin percentage of moisture：
The skin percentage of moisture=(skin weight in wet base-skin dry weight)/weight in wet base × 100%
Experimental result see the table below five
Table five
The skin percentage of moisture average value of the corresponding experiment mice of embodiment 5~24 is 72.187% as shown in Table 5,
Far above comparative example 1~7, being distinguished as of comparative example 5 and embodiment 1 does not add plant composition, the skin of corresponding experiment mice
The skin percentage of moisture is only 31.69%, illustrates that the main active ingredient of moisturizing is plant composition, contrast in emulsion of the present invention
The difference of example 1~4 and embodiment 5 does not add ginkgo biloba p.e respectively, evening primrose oil is not added, Tea Polyphenols, not is not added
The skin percentage of moisture for adding aloe barbadensis Miller polysaccharide and corresponding experiment mice is far below the skin of the experiment mice of embodiment 5
The skin percentage of moisture, it can be seen that ginkgo biloba p.e, evening primrose oil, Tea Polyphenols and aloe barbadensis Miller are more in plant composition
Sugared Synergistic, there is more preferable moisturizing effect.
Moisture-keeping efficacy is verified：
Experimental subjects：810 20-45 Sui female volunteers.
Experimental method：It is embodiment 5~24 and comparative example 1~7, every group of 30 people that 810 volunteers are randomly divided into 27 groups.
Dried after 810 volunteer's cleaning faces and be applied to face using corresponding emulsion, three times a day, continue 15 days, at 15 days
After 24h, room temperature be 25 DEG C of humidity be under conditions of 50% using Corneometer CM825 tests 30min and 8h after cutin
The moisture of layer.
Experimental result see the table below six
Table six
It is 85.395% to have the visible embodiment 5~24 of table six to smear water content average value after 30min, smears water content after 8h
Average value is 69.9455%, aqueous slippage average value 14.4495%, be and comparative example 1~7 smear 30min after water content not
To 67.21%, water content is smeared after 8h less than 37.22%, and aqueous slippage reaches more than 29.03%.Comparative example 5 is containing under water
Drop amount is up to 34.98%, it is seen that illustrate that the main active ingredient of moisturizing is plant composition in moisture surge treatment formula of the present invention, this
The reasonable science of formula of invention moisture surge treatment formula, ginkgo biloba p.e, evening primrose oil, Tea Polyphenols, the collaboration of aloe barbadensis Miller polysaccharide
Synergy, there is more preferable moistening effect.
By carrying out test experiments to the product of above-described embodiment 5~24, the laboratory report of acquirement shows, radiation proof of the present invention
Face cream is more than 99.5% to the absorptivity of the ran of ultraviolet 280~400, the absorption of radiation such as mechanical, electrical brain of opponent and anti-
The gross efficiency penetrated can reach more than 95%, there is one very big carry in terms of radiation proof compared with existing sun-proof face cream
It is high.
Above example only illustrates embodiment of the present invention, does not have any formal limitation to the present invention；Appoint
What is engaged in professional and technical personnel, all has the ability to make some changes using the technology contents disclosed or modifies, as equivalent
The equivalent embodiment of change, according to the technology of the present invention essence, simply modification, equivalent variations and modification is carried out to the present invention, is belonged to
In the range of technical solution of the present invention.
Claims (8)
1. a kind of emulsion with moisturizing anti-radiation effect, it is characterised in that the emulsion mainly includes following plant composition：
Ginkgo biloba p.e, evening primrose oil, Tea Polyphenols, aloe barbadensis Miller polysaccharide, the parts by weight of wherein each component are：
0.1-2 parts of ginkgo biloba p.e
0.1-5 parts of evening primrose oil
0.1-1.2 parts of Tea Polyphenols
0.2-1.5 parts of aloe barbadensis Miller polysaccharide.
2. a kind of emulsion with moisturizing anti-radiation effect according to claim 1, it is characterised in that the plant society
Each Parts by Ingredients of thing is：
0.5-1.5 parts of ginkgo biloba p.e
1-3 parts of evening primrose oil
0.5-1 parts of Tea Polyphenols
0.5-1.2 parts of aloe barbadensis Miller polysaccharide.
3. a kind of emulsion with moisturizing anti-radiation effect according to claim 1 or 2, it is characterised in that the ginkgo
The preparation method of leaf extract is as follows：Fresh ginkgo leaf is taken, by 1:The solid-liquid ratio (g/ml) of (10-15) soaks the ginkgo leaf
Enter concentration 65-85% alcohol solution dipping 60-90min；Feed liquid is placed in heating and refluxing extraction 1.5-3h in water-bath, filtered,
Filtrate is collected, filter residue repeats to extract once with 8 times of amount 75-85% ethanol, merges filtrate twice；Concentrate filtrate to no alcohol
Taste, concentrate is adsorbed by AB-8 macroporous resin columns, first with distillation water elution, then is used 60% ethanol elution, is collected 60%
Ethanol eluate, obtains the ginkgo biloba p.e after being concentrated under reduced pressure.
4. a kind of emulsion with moisturizing anti-radiation effect, it is characterised in that the emulsion is consisted of the following composition：
5. a kind of emulsion with moisturizing anti-radiation effect according to claim 1, it is characterised in that the emulsifying agent is
Stearine, methyl sesquistearate, PEG-20 methyls sesquistearate, the smooth stearate of sorb,
At least one of dimerization hydroxy stearic acid ester of polyglycereol -2.
6. a kind of emulsion with moisturizing anti-radiation effect according to claim 1, it is characterised in that the skin conditioning
Agent is at least one of stearic acid, stearyl alcohol, isopropyl myristate, octanoic acid/certain herbaceous plants with big flowers acid glycerol three ester.
7. a kind of emulsion with moisturizing anti-radiation effect according to claim 1, it is characterised in that the preservative is
At least one of butyl p-hydroxybenzoate, ethyl-para-hydroxybenzoate, Phenoxyethanol.
8. a kind of method for preparing the emulsion as described in claim any one of 1-7, it is characterised in that methods described includes following
Step：By emulsifying agent, skin conditioner, OXYBENZONE mixing put into oil phase pot heating stirring to 85 degree, stirring and dissolving as A phases
Heat preservation for standby use after completely；Glycerine, allantoin, deionized water mixing are added to heating stirring in aqueous phase pot as B and, to 85 degree, stirred
Mix heat preservation for standby use after dissolving completely；Emulsification pot is preheated to 60-65 degree, B phases are first pumped into by 50 revs/min of mixing speed, then will
A phases are pumped into, and are stirred 30 minutes, temperature is maintained at 85 degree；C is added to emulsification pot, homogeneous 3 minutes, insulated and stirred 30 minutes, temperature
Degree is maintained at 80-85 degree, 35 revs/min of mixing speed；The C phases are hydroxyethyl cellulose；42 degree of addition D phases are cooled to, are protected
Temperature stirring 10 minutes, 25-30 revs/min of mixing speed is eventually adding E phases, is incubated 10-20 minutes；The D phases are plant society
Thing, the E phases are preservative；Stirring is cooled to 40 degree of dischargings.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710190176.1A CN107007499A (en) | 2017-03-27 | 2017-03-27 | A kind of emulsion with moisturizing anti-radiation effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710190176.1A CN107007499A (en) | 2017-03-27 | 2017-03-27 | A kind of emulsion with moisturizing anti-radiation effect |
Publications (1)
| Publication Number | Publication Date |
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| CN107007499A true CN107007499A (en) | 2017-08-04 |
Family
ID=59445217
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710190176.1A Withdrawn CN107007499A (en) | 2017-03-27 | 2017-03-27 | A kind of emulsion with moisturizing anti-radiation effect |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511216A (en) * | 2016-12-28 | 2017-03-22 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Moisturizing cosmetic composition and application thereof |
| CN108524402A (en) * | 2018-07-09 | 2018-09-14 | 福建省海乐威生物工程有限公司 | A kind of face cream for having effects that cutin and repairing |
| CN109568221A (en) * | 2019-02-16 | 2019-04-05 | 陈伟伟 | A kind of Firm lotion and preparation method thereof that can be effectively crease-resistant |
| CN111973462A (en) * | 2019-05-23 | 2020-11-24 | 西安博和医疗科技有限公司 | Skin care compositions |
-
2017
- 2017-03-27 CN CN201710190176.1A patent/CN107007499A/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511216A (en) * | 2016-12-28 | 2017-03-22 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Moisturizing cosmetic composition and application thereof |
| CN108524402A (en) * | 2018-07-09 | 2018-09-14 | 福建省海乐威生物工程有限公司 | A kind of face cream for having effects that cutin and repairing |
| CN109568221A (en) * | 2019-02-16 | 2019-04-05 | 陈伟伟 | A kind of Firm lotion and preparation method thereof that can be effectively crease-resistant |
| CN111973462A (en) * | 2019-05-23 | 2020-11-24 | 西安博和医疗科技有限公司 | Skin care compositions |
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