CN113164499A - 含有熊去氧胆酸的老视的治疗或预防剂 - Google Patents

含有熊去氧胆酸的老视的治疗或预防剂 Download PDF

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Publication number
CN113164499A
CN113164499A CN201980081377.5A CN201980081377A CN113164499A CN 113164499 A CN113164499 A CN 113164499A CN 201980081377 A CN201980081377 A CN 201980081377A CN 113164499 A CN113164499 A CN 113164499A
Authority
CN
China
Prior art keywords
ursodeoxycholic acid
acid
lens
therapeutic
ursodeoxycholate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980081377.5A
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English (en)
Chinese (zh)
Inventor
加藤雅智
小田知子
木户一贵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of CN113164499A publication Critical patent/CN113164499A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
CN201980081377.5A 2018-12-18 2019-12-17 含有熊去氧胆酸的老视的治疗或预防剂 Pending CN113164499A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018-236717 2018-12-18
JP2018236717 2018-12-18
PCT/JP2019/049352 WO2020129964A1 (ja) 2018-12-18 2019-12-17 ウルソデオキシコール酸を含有する老視の治療または予防剤

Publications (1)

Publication Number Publication Date
CN113164499A true CN113164499A (zh) 2021-07-23

Family

ID=71100366

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980081377.5A Pending CN113164499A (zh) 2018-12-18 2019-12-17 含有熊去氧胆酸的老视的治疗或预防剂

Country Status (16)

Country Link
US (3) US20220072012A1 (enExample)
EP (1) EP3900728A4 (enExample)
JP (2) JP6771698B1 (enExample)
KR (1) KR20210105916A (enExample)
CN (1) CN113164499A (enExample)
AU (1) AU2019407391A1 (enExample)
BR (1) BR112021011653A2 (enExample)
CA (1) CA3123370A1 (enExample)
EA (1) EA202191684A1 (enExample)
IL (1) IL284004A (enExample)
MX (1) MX2021007161A (enExample)
MY (1) MY203280A (enExample)
PH (1) PH12021551412A1 (enExample)
SG (1) SG11202106216SA (enExample)
TW (1) TW202038966A (enExample)
WO (1) WO2020129964A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116211804A (zh) * 2023-05-09 2023-06-06 北京汇诚益健医药科技有限责任公司 熊去氧胆酸脂质组合物及其应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6771698B1 (ja) 2018-12-18 2020-10-21 参天製薬株式会社 ウルソデオキシコール酸を含有する老視の治療または予防剤
CA3210908A1 (en) 2021-02-15 2022-08-18 Santen Pharmaceutical Co., Ltd. Water-based pharmaceutical composition containing ursodeoxycholic acid or salt thereof
US20220349486A1 (en) * 2021-04-29 2022-11-03 Baker Hughes Oilfield Operations Llc Modulating pilot valve adapter
TW202412751A (zh) * 2022-08-09 2024-04-01 日商參天製藥股份有限公司 含有udca或其鹽之水性醫藥組合物

Citations (5)

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CN102178784A (zh) * 2011-04-20 2011-09-14 威海康博尔生物药业有限公司 一种用于治疗视力障碍和损伤并缓解视疲劳的联合疗法
WO2013025840A1 (en) * 2011-08-15 2013-02-21 Massachusetts Eye And Ear Infirmary Methods for preserving photoreceptor cell viability following retinal detachment
CN104083381A (zh) * 2014-07-29 2014-10-08 上海中医药大学 熊去氧胆酸的医药用途
WO2018147685A1 (ko) * 2017-02-09 2018-08-16 주식회사 유스바이오팜 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물
WO2018164113A1 (ja) * 2017-03-06 2018-09-13 学校法人 慶應義塾 マウス近視誘導モデル及び近視予防・抑制のための小胞体ストレス抑制剤

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EP2442647B1 (en) 2009-06-15 2016-03-16 Encore Health LLC Dithiol compounds, derivatives, and uses therefor
WO2016029197A1 (en) * 2014-08-22 2016-02-25 Kang Zhang Compositions and methods to treat and/or prevent vision disorders of the lens of the eye
CN109481392B (zh) * 2015-09-02 2021-12-24 盛世泰科生物医药技术(苏州)有限公司 一种用于预防和治疗白内障的眼用制剂及其制备方法
KR102252450B1 (ko) * 2017-02-09 2021-05-14 주식회사 아미코젠파마 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물
JP6771698B1 (ja) * 2018-12-18 2020-10-21 参天製薬株式会社 ウルソデオキシコール酸を含有する老視の治療または予防剤

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178784A (zh) * 2011-04-20 2011-09-14 威海康博尔生物药业有限公司 一种用于治疗视力障碍和损伤并缓解视疲劳的联合疗法
WO2013025840A1 (en) * 2011-08-15 2013-02-21 Massachusetts Eye And Ear Infirmary Methods for preserving photoreceptor cell viability following retinal detachment
CN104083381A (zh) * 2014-07-29 2014-10-08 上海中医药大学 熊去氧胆酸的医药用途
WO2018147685A1 (ko) * 2017-02-09 2018-08-16 주식회사 유스바이오팜 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물
WO2018164113A1 (ja) * 2017-03-06 2018-09-13 学校法人 慶應義塾 マウス近視誘導モデル及び近視予防・抑制のための小胞体ストレス抑制剤

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SONG,SHUHUA 等: "Cholesterol-derived bile acids enhance the chaperone activity of α-crystallines", 《CELL STRESS ＆CHAPERONES》 *
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李梦等: "熊胆粉制剂临床应用的研究进展", 《天津中医药》 *
瞿群威等主编: "《头颈部疾病针刀临床诊断与治疗》", 31 August 2014, 中国医药科技出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116211804A (zh) * 2023-05-09 2023-06-06 北京汇诚益健医药科技有限责任公司 熊去氧胆酸脂质组合物及其应用
CN116211804B (zh) * 2023-05-09 2025-09-05 北京汇诚益健医药科技有限责任公司 熊去氧胆酸脂质组合物及其应用

Also Published As

Publication number Publication date
BR112021011653A2 (pt) 2021-09-08
JP6771698B1 (ja) 2020-10-21
SG11202106216SA (en) 2021-07-29
EP3900728A1 (en) 2021-10-27
EA202191684A1 (ru) 2021-09-01
JP2021006548A (ja) 2021-01-21
US20220096497A1 (en) 2022-03-31
KR20210105916A (ko) 2021-08-27
AU2019407391A1 (en) 2021-07-01
WO2020129964A1 (ja) 2020-06-25
US20230040386A1 (en) 2023-02-09
US20220072012A1 (en) 2022-03-10
JPWO2020129964A1 (ja) 2021-02-15
IL284004A (en) 2021-08-31
EP3900728A4 (en) 2022-08-17
CA3123370A1 (en) 2020-06-25
TW202038966A (zh) 2020-11-01
PH12021551412A1 (en) 2022-05-02
MX2021007161A (es) 2021-10-13
US11419880B2 (en) 2022-08-23
MY203280A (en) 2024-06-21

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