CN113056284A - 通过肿瘤内和/或静脉内施用编码4-1bbl(cd137l)和/或cd40l的重组mva治疗癌症的疗法 - Google Patents

通过肿瘤内和/或静脉内施用编码4-1bbl(cd137l)和/或cd40l的重组mva治疗癌症的疗法 Download PDF

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Publication number
CN113056284A
CN113056284A CN201980076127.2A CN201980076127A CN113056284A CN 113056284 A CN113056284 A CN 113056284A CN 201980076127 A CN201980076127 A CN 201980076127A CN 113056284 A CN113056284 A CN 113056284A
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mva
tumor
1bbl
nucleic acid
recombinant
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CN201980076127.2A
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Chinese (zh)
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H·劳特巴赫
M·欣特贝格尔
J·梅迪纳埃切韦尔斯
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Bavarian Nordic AS
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CN201980076127.2A 2018-11-20 2019-11-20 通过肿瘤内和/或静脉内施用编码4-1bbl(cd137l)和/或cd40l的重组mva治疗癌症的疗法 Pending CN113056284A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18207238.9 2018-11-20
EP18207238 2018-11-20
US201962807720P 2019-02-19 2019-02-19
US62/807,720 2019-02-19
PCT/EP2019/081942 WO2020104531A1 (en) 2018-11-20 2019-11-20 Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l

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Publication Number Publication Date
CN113056284A true CN113056284A (zh) 2021-06-29

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CN201980076127.2A Pending CN113056284A (zh) 2018-11-20 2019-11-20 通过肿瘤内和/或静脉内施用编码4-1bbl(cd137l)和/或cd40l的重组mva治疗癌症的疗法

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US (1) US12390515B2 (enExample)
EP (1) EP3883599A1 (enExample)
JP (1) JP7625518B2 (enExample)
KR (1) KR20210094535A (enExample)
CN (1) CN113056284A (enExample)
AU (1) AU2019385665A1 (enExample)
BR (1) BR112021009856A8 (enExample)
CA (1) CA3119503A1 (enExample)
IL (1) IL283187A (enExample)
MX (1) MX2021005560A (enExample)
SG (1) SG11202104918PA (enExample)
WO (1) WO2020104531A1 (enExample)

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IL272546B2 (en) * 2017-08-24 2024-01-01 Bavarian Nordic As Combined therapy for the treatment of cancer with intravenous administration of recombinant MVA and antibody
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
PH12022551208A1 (en) 2019-11-18 2023-04-24 Janssen Biotech Inc Vaccines based on mutant calr and jak2 and their uses
CN114929268A (zh) * 2019-11-20 2022-08-19 巴法里安诺迪克有限公司 4-1bbl辅助的重组修饰的安卡拉痘苗病毒(mva)的医疗用途
IL293009B1 (en) * 2019-11-20 2025-09-01 Bavarian Nordic As Recombinant mva viruses for intratumoral and/or intravenous administration for cancer treatment
US20230174653A1 (en) * 2020-04-06 2023-06-08 St. Jude Children's Research Hospital, Inc. B7-h3 chimeric antigen receptors
WO2022009052A2 (en) 2020-07-06 2022-01-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
WO2022036495A1 (en) 2020-08-17 2022-02-24 Utc Therapeutics Inc. Lymphocytes-antigen presenting cells co-stimulators and uses thereof
US20240409608A1 (en) * 2021-10-26 2024-12-12 Navicure Biopharmaceuticals Limited Combination therapies against cancer and infectious diseases
WO2023118563A1 (en) 2021-12-23 2023-06-29 Bavarian Nordic A/S Therapy for modulating immune response with recombinant mva encoding il-12
WO2023118508A1 (en) * 2021-12-23 2023-06-29 Bavarian Nordic A/S Recombinant mva viruses for intraperitoneal administration for treating cancer
CN117004579B (zh) * 2023-06-29 2024-11-15 苏州恩立维生物科技有限公司 重组溶瘤牛痘病毒及其应用

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