CA3119503A1 - Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l - Google Patents

Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l Download PDF

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Publication number
CA3119503A1
CA3119503A1 CA3119503A CA3119503A CA3119503A1 CA 3119503 A1 CA3119503 A1 CA 3119503A1 CA 3119503 A CA3119503 A CA 3119503A CA 3119503 A CA3119503 A CA 3119503A CA 3119503 A1 CA3119503 A1 CA 3119503A1
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CA
Canada
Prior art keywords
mva
tumor
1bbl
nucleic acid
antigen
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Pending
Application number
CA3119503A
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English (en)
French (fr)
Inventor
Henning Lauterbach
Maria HINTERBERGER
Jose Medina Echeverz
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Bavarian Nordic AS
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Bavarian Nordic AS
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Publication of CA3119503A1 publication Critical patent/CA3119503A1/en
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4224—Molecules with a "CD" designation not provided for elsewhere
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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CA3119503A 2018-11-20 2019-11-20 Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l Pending CA3119503A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18207238.9 2018-11-20
EP18207238 2018-11-20
US201962807720P 2019-02-19 2019-02-19
US62/807,720 2019-02-19
PCT/EP2019/081942 WO2020104531A1 (en) 2018-11-20 2019-11-20 Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l

Publications (1)

Publication Number Publication Date
CA3119503A1 true CA3119503A1 (en) 2020-05-28

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CA3119503A Pending CA3119503A1 (en) 2018-11-20 2019-11-20 Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l

Country Status (12)

Country Link
US (1) US12390515B2 (enExample)
EP (1) EP3883599A1 (enExample)
JP (1) JP7625518B2 (enExample)
KR (1) KR20210094535A (enExample)
CN (1) CN113056284A (enExample)
AU (1) AU2019385665A1 (enExample)
BR (1) BR112021009856A8 (enExample)
CA (1) CA3119503A1 (enExample)
IL (1) IL283187A (enExample)
MX (1) MX2021005560A (enExample)
SG (1) SG11202104918PA (enExample)
WO (1) WO2020104531A1 (enExample)

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BR112020003669A2 (pt) * 2017-08-24 2020-09-01 Bavarian Nordic A/S terapia de combinação para tratamento do câncer com administração intravenosa de um mva recombinante e de um anticorpo
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
CA3161800A1 (en) 2019-11-18 2021-05-27 Janssen Biotech, Inc. Vaccines based on mutant calr and jak2 and their uses
EP4061406A1 (en) * 2019-11-20 2022-09-28 Bavarian Nordic A/S Recombinant mva viruses for intratumoral and/or intravenous administration for treating cancer
JP7670705B2 (ja) * 2019-11-20 2025-04-30 バヴァリアン・ノルディック・アクティーゼルスカブ ４－１ｂｂｌアジュバント添加した組み換え改変ワクシニアウイルスアンカラ（ｍｖａ）の医学的使用
WO2021207171A1 (en) * 2020-04-06 2021-10-14 St. Jude Children's Research Hospital, Inc. B7-h3 chimeric antigen receptors
WO2022009052A2 (en) 2020-07-06 2022-01-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
WO2022036495A1 (en) 2020-08-17 2022-02-24 Utc Therapeutics Inc. Lymphocytes-antigen presenting cells co-stimulators and uses thereof
JP2024539940A (ja) * 2021-10-26 2024-10-31 ナビキュア バイオファーマシューティカルズ リミテッド がん及び感染症に対する組み合わせ療法
WO2023118563A1 (en) 2021-12-23 2023-06-29 Bavarian Nordic A/S Therapy for modulating immune response with recombinant mva encoding il-12
EP4452305A1 (en) * 2021-12-23 2024-10-30 Bavarian Nordic A/S Recombinant mva viruses for intraperitoneal administration for treating cancer
CN117004579B (zh) * 2023-06-29 2024-11-15 苏州恩立维生物科技有限公司 重组溶瘤牛痘病毒及其应用

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