CN113017089A - Meal replacement composition for improving basal metabolism level and preparation method and application thereof - Google Patents
Meal replacement composition for improving basal metabolism level and preparation method and application thereof Download PDFInfo
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- CN113017089A CN113017089A CN202110387206.4A CN202110387206A CN113017089A CN 113017089 A CN113017089 A CN 113017089A CN 202110387206 A CN202110387206 A CN 202110387206A CN 113017089 A CN113017089 A CN 113017089A
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The invention discloses a meal replacement composition for improving the basal metabolic level, a preparation method and application thereof, wherein the composition comprises the following raw materials: 3-4 parts of dietary fiber, 4-5 parts of oligosaccharide, 3-5 parts of protein powder, 3-5 parts of fatty acid powder, 1-4 parts of traditional Chinese medicine extract, 0.5-1.5 parts of white kidney bean extract, 0.5-1.5 parts of guarana extract, 0.01-0.1 part of cubilose acid, 0.02-0.05 part of compound vitamin and 0.3-0.7 part of compound mineral substance; the invention also discloses a meal replacement composition for improving the basal metabolic level, a preparation method and application thereof. The invention provides a meal replacement composition for achieving the purposes of losing weight, reducing blood fat and reducing blood sugar by improving the basal metabolic rate, delaying sugar absorption and enhancing satiety.
Description
Technical Field
The invention relates to the field of food, in particular to a meal replacement composition for improving the basal metabolic level, a preparation method and application thereof.
Background
With the change of life style and dietary structure, the incidence of obesity, hyperlipidemia and diabetes of Chinese people is high. According to the reports of Chinese resident nutrition and chronic disease symptoms (2020), the overweight and obesity rates of residents of all ages in city and countryside continue to increase, the overweight and obesity rates of residents of 18 years and older are 34.3% and 16.4% respectively, that is, the total incidence of obesity and overweight in people of 18 years and older is more than 50%.
Obesity is one of the important causes of high incidence of cardiovascular and cerebrovascular diseases and diabetes, and the incidence of three-high diseases such as diabetes, dyslipidemia (hyperlipidemia) and hypertension of obese people is obviously higher than that of normal people. In obese people, waist circumference and BMI are in obvious positive correlation with metabolic disorder disease risk, and with the increase of BMI and waist circumference, the diabetes patient risk is increased significantly [ Houxu hong. obesity morbidity transition and its influence on adult diabetes and pre-diabetes burden in China-doctor thesis of Shanghai university of transportation, 2014 ]. Weight loss can significantly reduce the burden of metabolic disease and increase the sensitivity of body cells to insulin receptors. And even patients already suffering from diabetes can obviously relieve the symptoms of diabetes by losing 5% -10% of the body weight for 3 months to half a year. A diabetes milestone research result as published by The top-grade medical journal "Lancet" (The Lancet) in 2018: patients successfully reversed type 2diabetes by dieting to lose weight. Wherein 86% of the individuals with weight loss greater than 15kg have diabetes alleviated; 57% of the groups with 10-15 kg weight loss were relieved, 34% of the groups with 5-10 kg weight loss were relieved [ Lean ME, Leslie WS, Barnes AC, et al Primary care-led weight management for the discovery of type 2diabetes (RecT), an open-label, cluster-random three Lancet,2018,391(10120) ].
The most central problem of weight loss is to maintain the energy negative balance in a certain period of time, and to reduce the weight by ensuring the energy negative balance through eating less and moving more, but a key factor influencing the body weight is the basal metabolic rate. People with low basal metabolic rate have difficulty in losing weight and are easy to rebound, and the overweight and obese people have more serious excess weight and lower basal metabolic rate, so that the improvement of the metabolic rate is a key measure for maintaining the long-term weight-losing effect.
There are many measures to increase the basal metabolic rate of the body, such as increasing the basal metabolic rate gradually by exercising and increasing lean body mass, while in the medical field, the basal metabolic rate is mainly increased by central nervous stimulants (such as caffeine and dopamine drugs) and some hormones (such as thyroid hormone), but the basal metabolic rate has not been widely popularized as a weight-reducing drug due to the side effects of the nervous stimulants and hormones. The traditional Chinese medicine is a huge medical treasure in China, and a plurality of traditional Chinese medicine substances can improve the metabolic rate of an organism and are applied to the weight-losing process [ Lilianzhen, LieXiaoqing, Ruiyan, and the like.
The Chinese patent application numbers are: 201810049260.6, application date is 1 month and 18 days 2018, publication date is: patent names of 8 months and 10 days in 2018 are as follows: the invention discloses a special diet product with four-high prevention and treatment functions for people and a preparation method thereof, and the special diet product comprises food materials such as kudzu root powder, hawthorn powder, Chinese yam, ginkgo, oat, pumpkin seed, garlic, onion, carrot, coix seed, buckwheat and the like, and also comprises extracts of traditional Chinese medicines such as lycopodium clavatum, osbeckia chinensis, poria cocos, sargentgloryvine stem, polygonum cuspidatum, medlar, salvia miltiorrhiza and wild chrysanthemum, and the extracts can remarkably adjust four-high levels in a body, improve nutrition basal metabolism in the body and reduce unnecessary metabolic burden while ensuring comprehensive nutrition supply.
The above documents and patents show that people can increase the basal metabolic rate of the body by reasonable utilization of sports, dietotherapy and Chinese herbal medicines on the premise of ensuring the basic nutritional requirements of the body, so as to achieve the purposes of accelerating the weight-losing effect and preventing relapse. Meanwhile, as mentioned above, the sensitivity of an insulin receptor of a body is increased while the basal metabolic rate is improved and the weight is reduced, the insulin tolerance degree of an obese patient is reduced, and the symptoms of diabetes are reduced, so that the purpose of one arrow double carving is achieved.
However, according to our previous investigation results, it is shown that: the traditional Chinese medicine for losing weight and reducing fat applied at present either exceeds the scope of homology of medicine and food and new food raw materials and cannot be widely popularized in the public, or is health food (Jian Zi size) or common functional food (SC size), but has poor and attractive effect and is easy to rebound.
The invention is based on the precise intervention of multiple factors for obesity and diabetes, and comprises (1) suppressing appetite and improving basal metabolic rate by using extracts of traditional Chinese medicines and new food raw materials which are homologous as food and medicine; (2) by administering sufficient amounts of dietary fiber and oligosaccharides, the gastric emptying time is prolonged, the feeling of hunger is reduced to reduce energy intake, the stool volume is increased to increase toxin excretion, and insulin resistance is reduced by improving the intestinal flora and by adjusting the proportion of intestinal flora; (3) the white kidney bean extract and the L-arabinose respectively inhibit amylase and sucrase, and the decomposition and absorption speed of sugar is delayed, so that the speed of postprandial blood sugar rise is delayed and the rise amplitude of the postprandial blood sugar is reduced; (4) the lack of protein and energy during the period of weight loss and sugar control of meal replacement is corrected by properly increasing the content of protein and fat in the composition, so as to avoid reducing the metabolic level and resistance of the body, and the metabolism of three nutrients (protein, fat and carbohydrate) in the body is promoted by adding vitamins and minerals, so that the occurrence of diabetic complications is avoided. Based on the action mechanism, the invention takes Chinese medicinal material extracts which are mainly of medicine-food homologous class and new food raw materials for improving the basic metabolism level as main materials, combines dietary fiber, oligosaccharide and white kidney bean extracts for inhibiting starch decomposition, adds a proper amount of protein, fatty acid, vitamin and mineral substances, forms meal replacement powder or solid beverage with food characteristics (SC number) after correcting the taste, and can also add the composition into other food raw materials according to the requirement to prepare meal replacement bars, meal replacement chocolates, meal replacement biscuits and meal replacement soft sweets with the functions of losing weight and reducing blood sugar.
The final purpose of the invention is to improve the metabolic level of the organism, reduce the intake of energy, delay the decomposition and absorption of carbohydrate, improve the intestinal flora and the intestinal function, and achieve the purposes of losing weight, reducing fat, reducing postprandial blood sugar and improving the symptom of diabetes by the precise intervention of multiple target spots on the basis of health management without suffering from hunger.
Disclosure of Invention
The invention mainly aims to provide a meal replacement composition for achieving the purposes of losing weight, reducing fat and reducing blood sugar by improving basal metabolic rate, delaying sugar absorption and enhancing satiety.
In order to achieve the above purpose, the present invention provides a meal replacement composition for reducing blood fat and weight and reducing blood sugar level of diabetic patients by increasing basal metabolic rate, wherein the composition comprises the following raw materials by weight: 3-4 parts of dietary fiber, 4-5 parts of oligosaccharide, 3-5 parts of protein powder, 3-5 parts of fatty acid powder, 1-4 parts of traditional Chinese medicine extract, 0.5-1.5 parts of guarana extract, 0.5-1.5 parts of white kidney bean extract, 0.01-0.1 part of cubilose acid powder, 0.02-0.05 part of composite vitamin and 0.3-0.7 part of composite mineral;
the traditional Chinese medicine extract comprises the following raw materials in parts by weight: 2-3 parts of ginseng (artificially planted for less than five years), 1-2 parts of onion, 1-3 parts of sea buckthorn, 1-2 parts of dried ginger, 1-2 parts of purple perilla, 2-3 parts of citrus young fruit, 1-2 parts of cinnamon, 2-3 parts of mulberry leaf, 2-3 parts of shinyleaf yellowhorn and 2-3 parts of plukenetia volubilis.
The dietary fiber comprises the following raw materials in parts by weight: 1-3 parts of oat fiber, 1-3 parts of konjac fiber and 2-4 parts of inulin; the oligosaccharide comprises the following raw materials in parts by weight: 1-3 parts of fructo-oligosaccharide, 0.5-2 parts of L-arabinose and 0.5-2 parts of galacto-oligosaccharide.
The protein powder comprises the following raw materials in parts by weight: 2-4 parts of whey protein powder and 2-4 parts of soybean protein isolate powder;
the fatty acid powder comprises the following raw materials in parts by weight: 1-3 parts of medium-long chain fatty acid powder, 1-3 parts of safflower seed oil powder and 1-3 parts of coconut oil powder.
The compound vitamin comprises the following raw materials in parts by weight: 0.2-0.5 part of beta-carotene, 0.4-0.7 part of retinyl acetate, 10-15 parts of thiamine hydrochloride, 10-15 parts of riboflavin, 12-18 parts of nicotinic acid, 2-5 parts of D-calcium pantothenate, 10-15 parts of pyridoxine hydrochloride, 0.1-0.3 part of folic acid, 0.002-0.005 part of cyanocobalamin, 10-15 parts of cholecalciferol and 8-12 parts of dl-alpha-tocopherol acetate;
the composite mineral comprises 10-15 parts of magnesium gluconate, 0.5-2 parts of zinc gluconate, 20-30 parts of calcium carbonate and 0.5-2 parts of selenium yeast.
Preferably, the meal replacement composition for reducing blood fat and weight and reducing blood sugar level of a diabetic patient by improving basal metabolic rate comprises the following raw materials in parts by weight: 2-3 parts of oat fiber, 2-3 parts of konjac fiber, 2-3 parts of inulin, 2-5 parts of fructo-oligosaccharide, 1-2 parts of L-arabinose and 2-3 parts of whey protein powder;
the feed also comprises 2-3 parts of soybean protein isolate powder, 1-3 parts of medium-long chain fatty acid powder, 1-2 parts of safflower seed oil powder, 1-2 parts of coconut oil powder, 2-4 parts of traditional Chinese medicine extract, 0.5-1 part of white kidney bean extract, 0.5-1.5 parts of guarana extract, 0.03-0.06 part of cubilose acid powder, 0.003-0.006 part of compound vitamin and 0.07-0.09 part of compound mineral substance.
Another object of the invention is: provides a preparation method and application of a meal replacement composition for improving basal metabolic rate, reducing fat and weight and reducing blood sugar level of a diabetic patient.
In order to achieve the above objects, the present invention provides a method for preparing a meal replacement composition for increasing basal metabolic rate, reducing blood fat and weight, and lowering blood sugar level of diabetic patients, comprising the following steps:
1) preparing medicinal and edible Chinese medicinal extract powder as new food raw materials;
2) compounding the dietary fiber, the oligosaccharide, the protein powder, the fatty acid powder, the white kidney bean extract, the cubilose acid powder, the compound vitamin and the compound mineral substance;
3) the taste is adjusted to form meal replacement powder or solid beverage with the effects of losing weight and reducing blood sugar;
4) adding into food raw materials to prepare meal replacement bar, meal replacement chocolate, meal replacement biscuit or meal replacement soft candy;
the preparation method of the traditional Chinese medicine extract powder comprises the following steps: weighing ginseng (artificially planted for less than five years), onion, sea buckthorn, dried ginger, purple perilla, citrus immature fruit, cinnamon, mulberry leaf, shinyleaf yellowhorn and plukenetia volubilis fruit in proportion, crushing the composition to 20-30 meshes, adding 15 times of purified water, decocting for 1-2 h, repeatedly decocting for three times, combining decoction, concentrating under reduced pressure, and spray drying to obtain the traditional Chinese medicine extract powder.
The method also comprises mixing dietary fiber, oligosaccharide, protein, lipid and Chinese medicinal extract, adding sweetener and sour taste regulator, or adding into food material to make into meal replacement bar, meal replacement chocolate, meal replacement biscuit or meal replacement soft candy.
The meal replacement composition for improving the basal metabolic level is applied to weight reduction and diabetic meal replacement.
The composition is prepared into powder, and the prepared powder is subpackaged into 10-25 g of independent packaging bags for later use; the powder can be used as meal replacement powder to replace 1 dinner every day, or used as solid beverage before meal to reduce meal amount of lunch and dinner and lower postprandial blood sugar.
The invention has the advantages that in the process of losing weight, lowering lipid and lowering blood sugar, the basic metabolism of a weight-losing person is obviously improved without over-excitation, so the weight-losing speed is high, the weight-losing person is not easy to rebound, in addition, the composition provides enough dietary fiber and oligosaccharide, and simultaneously, high-quality protein and partial fatty acid are supplemented, so the excessive ingestion caused by hunger is not easy to occur, the intestinal flora and the insulin resistance can be improved, therefore, the comprehensive intervention is carried out from multiple aspects aiming at the reasons of obesity and diabetes, and the risks and the hazards of chronic diseases such as three-high disease and the like caused by obesity and the insulin resistance are further reduced.
Particularly, the composition is added with N-acetylneuraminic acid (also called cubilose acid and sialic acid) powder and guarana extract in consideration of the requirement of losing weight of young women. This is because bird's nest acid can promote the synthesis of skin collagen, increase the moisture and elasticity of the skin, and make the skin more beautiful and glossy, so that people can lose weight without causing the skin to wrinkle, become loose and lose elasticity [ Dongjiaohui, tangqiao, chuanyuan, etc.. compared with 2019,45 (17): 73-78], thus meeting the psychological needs of young women for weight loss; a large amount of research evidence shows that the guarana does not have any addiction, is a food natural spice which is legally added in the food additive standard of China (the food safety national standard food additive use standard (GB 2760 + 2014)), and has the effects of improving the excitability of central nerves, improving the basal metabolic rate, and quickly recovering physical fatigue [ Shenguo, Yetian, Zhouyang, and the like ].
The invention can better ensure the content of effective substances and the efficacy of the composition through the self-made traditional Chinese medicine extract powder, and is favorable for controlling the cost and popularizing in a larger range (particularly in middle-low population), thereby generating huge social and economic values.
The implementation, functional features and advantages of the present invention will be further explained with reference to the embodiments.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that all the directional indicators (such as up, down, left, right, front, and rear … …) in the embodiment of the present invention are only used to explain the relative position relationship between the components, the motion situation, and the like in a specific posture, and if the specific posture is changed, the directional indicator is changed accordingly.
In the present invention, unless otherwise expressly stated or limited, the terms "connected," "secured," and the like are to be construed broadly, and for example, "secured" may be a fixed connection, a removable connection, or an integral part; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In addition, the descriptions related to "first", "second", etc. in the present invention are only for descriptive purposes and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.
Example 1
The invention provides a meal replacement composition for improving the basal metabolic level.
In one embodiment of the invention, the meal replacement composition for improving the basal metabolic level comprises the following raw materials in parts by weight: 3-4 parts of dietary fiber, 4-5 parts of oligosaccharide, 3-5 parts of protein powder, 3-5 parts of fatty acid powder, 1-4 parts of traditional Chinese medicine extract, 0.5-1.5 parts of white kidney bean extract, 0.5-1.5 parts of guarana extract, 0.01-0.1 part of cubilose acid powder, 0.02-0.05 part of composite vitamin and 0.3-0.7 part of composite mineral;
the traditional Chinese medicine extract powder comprises the following raw materials in parts by weight: 2-3 parts of ginseng (artificially planted for less than five years), 1-2 parts of onion, 1-3 parts of sea buckthorn, 1-2 parts of dried ginger, 1-2 parts of purple perilla, 2-3 parts of citrus young fruit, 1-2 parts of cinnamon, 2-3 parts of mulberry leaf, 2-3 parts of shinyleaf yellowhorn and 2-3 parts of plukenetia volubilis.
In this embodiment, preferably, the dietary fiber comprises the following raw materials in parts by weight: 1-3 parts of oat fiber, 1-3 parts of konjac fiber and 2-4 parts of inulin; the oligosaccharide comprises the following raw materials in parts by weight: 1-3 parts of fructo-oligosaccharide, 0.5-2 parts of L-arabinose and 0.5-2 parts of galacto-oligosaccharide.
In this embodiment, preferably, the protein powder includes the following raw materials in parts by weight: 2-4 parts of whey protein and 2-4 parts of soybean protein isolate;
in this embodiment, preferably, the fatty acid powder includes the following raw materials in parts by weight: 1-3 parts of medium-long chain fatty acid powder, 1-3 parts of safflower seed oil powder and 1-3 parts of coconut oil powder.
In this embodiment, preferably, the vitamin complex comprises the following raw materials in parts by weight: 0.2-0.5 part of beta-carotene, 0.4-0.7 part of retinyl acetate, 10-15 parts of thiamine hydrochloride, 10-15 parts of riboflavin, 12-18 parts of nicotinic acid, 2-5 parts of D-calcium pantothenate, 10-15 parts of pyridoxine hydrochloride, 0.1-0.3 part of folic acid, 0.002-0.005 part of cyanocobalamine, 10-15 parts of cholecalciferol and 8-12 parts of dl-alpha-tocopherol acetate, wherein the composite mineral substances comprise 10-15 parts of magnesium gluconate, 0.5-2 parts of zinc gluconate, 20-30 parts of calcium carbonate and 0.5-2 parts of yeast selenium.
In this embodiment, further, preferably, the dietary fiber further includes the following raw materials in parts by weight: 2-3 parts of oat fiber, 2-3 parts of konjac fiber and 2-3 parts of inulin;
in this embodiment, further, preferably, the meal replacement composition includes the following raw materials in parts by weight: 2-3 parts of oat fiber, 2-3 parts of konjac fiber, 2-3 parts of inulin, 2-5 parts of fructo-oligosaccharide, 1-2 parts of L-arabinose, 1-2 parts of galacto-oligosaccharide and 2-3 parts of whey protein powder;
the feed also comprises 2-3 parts of soybean protein isolate powder, 1-3 parts of medium-long chain fatty acid powder, 1-2 parts of safflower seed oil powder, 1-2 parts of coconut oil powder, 2-4 parts of traditional Chinese medicine extract powder, 1-1.5 parts of guarana extract, 0.5-1 part of white kidney bean extract, 0.03-0.06 part of cubilose acid powder, 0.003-0.006 part of compound vitamin and 0.07-0.09 part of compound mineral substance.
In this embodiment, the dietary fiber includes two or more of oat fiber, konjac fiber, and inulin; the oligosaccharide comprises two or more of fructo-oligosaccharide, L-arabinose and galacto-oligosaccharide; the protein powder comprises whey protein and soybean protein isolate; the fatty acid powder comprises two or more of medium-long chain fatty acid powder, safflower seed oil powder and coconut oil powder;
the Chinese medicinal extract powder comprises water extracts of two or more Chinese medicinal materials including Ginseng radix (artificially planted for less than five years), Bulbus Allii Cepae, fructus Hippophae, Zingiberis rhizoma, Perillae herba, young Citrus reticulata fruit, cortex Cinnamomi, folium Mori, xanthoceras sorbifolia, and MEIGENGGUO;
the compound vitamin comprises the following raw materials in parts by weight: the composite mineral comprises two or more of beta-carotene, retinyl acetate, thiamine hydrochloride, riboflavin, nicotinic acid, D-calcium pantothenate, pyridoxine hydrochloride, folic acid, cyanocobalamin, cholecalciferol and dl-alpha-tocopherol acetate, and the composite mineral comprises the following raw materials in parts by weight: two or more of magnesium gluconate, zinc gluconate, calcium carbonate and selenium yeast.
In this embodiment, the dietary fiber includes two or more of oat fiber, konjac fiber, and inulin; the oligosaccharide comprises two or more of fructo-oligosaccharide, L-arabinose and galacto-oligosaccharide; the protein powder comprises whey protein powder and soybean protein isolate powder; the fatty acid powder comprises two or more of medium-long chain fatty acid powder, safflower seed oil powder and coconut oil powder.
In this embodiment, it is further preferable that the composition comprises 2 to 3 parts of oat fiber, 2 to 3 parts of konjac fiber, 1 to 3 parts of inulin, 2 to 5 parts of fructo-oligosaccharide, 1 to 3 parts of L-arabinose, 1 to 2 parts of galacto-oligosaccharide, 2 to 3 parts of whey protein powder, 2 to 3 parts of soy protein isolate powder, 1 to 3 parts of medium-long chain fatty acid powder, 1 to 2 parts of safflower seed oil powder, 1 to 2 parts of coconut oil powder, 0.5 to 1 part of white kidney bean extract, 1 to 1.5 parts of guarana extract, 0.03 to 0.06 part of cubilose acid, 2 to 4 parts of traditional Chinese medicine extract powder, 0.003 to 0.006 part of vitamin complex, and 0.07 to 0.09 part of complex mineral.
Preferably, 2-3 parts of oat fiber, 2-3 parts of konjac fiber, 2-5 parts of fructo-oligosaccharide, 1-3 parts of L-arabinose, 2-3 parts of whey protein powder, 2-3 parts of soybean protein isolate powder, 1-3 parts of medium-long chain fatty acid powder, 1-2 parts of coconut oil powder, 0.5-1 part of white kidney bean extract, 0.05-0.06 part of cubilose acid, 2-3 parts of traditional Chinese medicine extract powder, 0.004-0.005 part of compound vitamin and 0.07-0.08 part of compound mineral substance.
Example 2
The invention also provides a preparation method and application of the weight-losing composition for improving the basal metabolic level.
The preparation method of the weight-losing composition for improving the basal metabolic level comprises the following steps:
1) preparing traditional Chinese medicine extract powder;
2) the dietary fiber, the oligosaccharide, the protein powder, the fatty acid powder, the white kidney bean extract, the cubilose acid powder, the compound vitamin and the compound mineral are compounded,
3) the taste is adjusted to form meal replacement powder or solid beverage with the effects of losing weight and reducing blood sugar;
4) the composition can be added into other food materials to prepare instant food such as meal replacement bar, meal replacement chocolate, meal replacement biscuit, meal replacement soft candy and the like.
The preparation method of the traditional Chinese medicine extract powder comprises the following steps: weighing ginseng (artificially planted for less than five years), onion, sea buckthorn, dried ginger, purple perilla, citrus immature fruit, cinnamon, mulberry leaf, shinyleaf yellowhorn and plukenetia volubilis fruit in proportion, crushing the composition to 20-30 meshes, adding 15 times of purified water, decocting for 1-2 h, repeatedly decocting for three times, combining decoction, concentrating under reduced pressure, and spray drying to obtain the traditional Chinese medicine extract powder.
In this embodiment, the method preferably further comprises mixing the dietary fiber, oligosaccharide, protein, lipid and herbal extract thoroughly, and adding sweetener and acidity regulator.
In this embodiment, the raw materials of the composition of the powder of traditional Chinese medicine extract of medicinal and edible source and new food raw materials include 2-3 parts of ginseng (artificially planted for less than five years), 1-2 parts of onion, 1-3 parts of sea buckthorn, 1-2 parts of dried ginger, 1-2 parts of perilla, 2-3 parts of citrus young fruit, 1-2 parts of cinnamon, 2-3 parts of mulberry leaf, 2-3 parts of shinyleaf yellowhorn and 2-3 parts of plukenetia volubilis linneo.
In this embodiment, the preparation method of the powder of traditional Chinese medicine extract as a medicinal and edible source and a new food raw material comprises the following steps: 2-3 parts of two or more commercially available traditional Chinese medicine decoction pieces of ginseng (artificially planted for less than five years), 1-2 parts of onion, 1-3 parts of sea buckthorn, 1-2 parts of dried ginger, 1-2 parts of purple perilla, 2-3 parts of citrus young fruit, 1-2 parts of cinnamon, 2-3 parts of mulberry leaf, 2-3 parts of shinyleaf yellowhorn and 2-3 parts of plukenetia volubilis fruit are weighed according to a proportion, the composition is crushed to 20-30 meshes, purified water 15 times of the composition is added for decoction for 1-2 hours, the decoction is repeatedly decocted for three times, decoction solutions are combined, and traditional Chinese medicine extract powder is obtained through reduced pressure concentration and spray drying.
The embodiment also provides application of the meal replacement composition for improving the basal metabolism level in weight loss and diabetic meal replacement.
In this embodiment, preferably, the composition further comprises powder, and the prepared powder is divided into 10 to 25 g; the powder can be used as meal replacement powder to replace 1 supper per day, or used as solid beverage before meal to reduce meal consumption of lunch and supper.
Further, the composition can be added into other food raw materials to prepare instant food such as meal replacement sticks, meal replacement chocolates, meal replacement biscuits or meal replacement soft sweets.
Example 3
In this embodiment, in addition, a method for preparing a medicinal and edible traditional Chinese medicine extract is also provided
Weighing 200g of commercially available traditional Chinese medicine decoction pieces of ginseng (artificially planted for less than five years), 100g of onion, 150g of sea-buckthorn, 100g of dried ginger, 150g of perilla, 250g of citrus young fruit, 150g of cinnamon, 200g of mulberry leaf, 150g of shinyleaf yellowhorn leaf and 175g of mei vine fruit leaf according to a proportion, and crushing the weighed traditional Chinese medicine materials into 20-30 meshes. Placing the crushed Chinese medicinal materials in an extraction tank, adding 15 times of purified water, steaming for 180 minutes, pouring the liquid medicine into a container, adding 10 times of purified water, and continuously steaming for 120 minutes; then the two parts of liquid are put into a concentration tank to be mixed evenly, and then are continuously concentrated under reduced pressure until the volume reaches 4g of original medicine/ml, and the traditional Chinese medicine extract powder is prepared for standby after spray drying.
Example 4
The embodiment also provides a preparation method of the weight-losing and sugar-reducing meal replacement powder for improving the basal metabolic level
The following raw materials are purchased with food production licenses and meeting the relevant national and enterprise standards: oat fiber powder, konjac fiber powder, 97% of fructo-oligosaccharide and L-arabinose, 90% of whey protein powder and soybean protein isolate powder, 70% of medium-long chain fatty acid powder and coconut oil powder, guarana extract, 95% of cubilose acid powder and white kidney bean extract with activity more than 4000 units;
according to the regulation of national standard GB14880-2012 'food nutrition enhancer use standard', composite vitamins are prepared by professional manufacturers, and the specific quality is as follows: 0.35g of beta-carotene, 0.5g of retinol acetate, 1.2g of thiamine hydrochloride, 1.2g of riboflavin, 15g of nicotinic acid, 4g of calcium pantothenate, 1.2g of pyridoxine hydrochloride, 0.2g of folic acid, 0.004g of cyanocobalamin, 0.001g of cholecalciferol, 10g of dl-alpha-tocopherol acetate, and maltodextrin is added to 100g and fully and uniformly mixed;
according to the regulation of national standard GB14880-2012 'food nutrition enhancer use standard', composite mineral substances are prepared by professional manufacturers, and the specific quality is as follows: 13g of magnesium gluconate, 1g of zinc gluconate, 25g of calcium carbonate and 0.03g of yeast selenium, adding maltodextrin to 100g, and fully and uniformly mixing.
The purchased and self-made raw materials are accurately weighed, and the specific mass of the raw materials is 25g of oat fiber, 20g of konjac fiber, 25g of fructo-oligosaccharide, 15g of L-arabinose, 20g of whey protein, 20g of soybean protein isolate, 20g of medium-long-chain fatty acid powder, 15g of coconut oil powder, 7.5g of white kidney bean extract, 8.5g of guarana extract, 0.05g of cubilose acid, 3g of traditional Chinese medicine extract, 0.004g of compound vitamin and 0.075g of compound mineral substance, after the raw materials are fully and uniformly mixed, 7.5g of lemon powder and 1.25g of 95% stevioside are added to adjust the taste, the raw materials are subpackaged into 20 g/bag, and the bag is sealed and stored in the shade for later use.
Example 5
In this example, the effect of the herbal extract on body fat and related metabolic hormones in obese rats
(1) Animal grouping and model preparation
Taking 48 SPF-grade SD rats (purchased from Shanghai new drug evaluation center) with the weight of 120-140 g, and dividing the SD rats into four groups, namely a normal control group, a normal intervention group, an obesity model group and an obesity intervention group, wherein each group comprises 12 rats. After the animals are adaptively fed for one week, feeding common rat feed to a normal control group and a normal intervention group; high calorie feed was fed to the obesity model group and the obesity intervention group [ luxiaojun, wusen, zhangju, etc.. experimental studies for establishing a rat obesity model using high calorie feed, experimental animals and comparative medicine, 2020,40 (5): 374-383 ], normally drinking water, weighing for 2 times per week, and after continuously raising for 4 weeks, the average body weight of the rats in the obese model group and the obese intervention group is more than 20 percent greater than that of the rats in the normal control group and the normal intervention group (see table 1), which indicates that the molding is successful.
Feeding the normal control group and the normal intervention group with common feed and feeding the obesity model group and the obesity intervention group with common high-energy feed from the fifth week, wherein the normal control group and the obesity model group are perfused with distilled water every morning, the perfused amount is 0.3ml/100g of body mass, the normal intervention group and the obesity intervention group are perfused with 0.3ml/100g of body mass of the traditional Chinese medicine extract (4 g of raw medicine/ml) prepared in example 1, after continuous perfusing for 6 weeks, feeding is stopped from 10 nights, weighing is carried out after 8 o' clock on the next day, blood is taken through an abdominal main artery under pentobarbital sodium anesthesia and centrifuged, serum is separated and placed at-80 ℃ for standby, meanwhile, fat tissues around the kidney and around the testis are taken, the visceral fat percentage is calculated as (fat tissue (g + week of the testis)/final body mass (g) × 100%, and single-factor analysis is carried out, the specific indexes are shown in Table 1.
(2) Effect of herbal extracts on body weight and visceral fat in obese rats
TABLE 1 Effect of herbal extracts on body weight and visceral fat in obese rats
Note: compared to normal control group,: p is a radical of<0.05,**:p<0.01; in comparison with the obesity model group,#: p<0.05。
as can be seen from the results in Table 1, the body weight of each group of rats was significantly increased with the extension of molding time, and the body weight and the visceral fat percentage of the rats fed with normal feed after the intervention of the traditional Chinese medicine had no significant effect, but the body weight and the visceral fat area of the obese rats were significantly reduced.
(3) Effect of Chinese medicinal extract on metabolism-related hormone of obese rats
Collecting the prepared serum, and detecting hormone index (cortisol (COR) and triiodothyronine (T) related to endocrine and metabolism in serum by radioimmunoassay3) Thyroxine (T)4) Testosterone (T)]And carrying out one-factor variance analysis, wherein specific indexes are shown in a table 2.
TABLE 2 Effect of herbal extracts on body weight and visceral fat in obese rats
Group of | COR(ng/ml) | T3(ng/ml) | T4(ng/ml) | T(ng/ml) |
Normal control group | 11.7±2.27 | 76.3±4.33 | 0.57±0.03 | 5.7±0.42 |
Normal intervention group | 10.3±1.62 | 71.1±3.14 | 0.53±0.02 | 5.1±0.39 |
Obesity model group | 7.1±1.24 | 53.3±4.17** | 0.39±0.04* | 4.3±0.33* |
Obesity intervention group | 9.8±1.17 | 70.4±3.43*# | 0.48±0.03*# | 4.9±0.27*# |
Note: compared to normal control group,: p is a radical of<0.05,**:p<0.01; in comparison with the obesity model group,#: p<0.05。
as can be seen from the results in Table 2, obese rats had no significant effect on Corticosterone (COR), but gave thyroxine T3、T4And the testosterone (T) level is obviously reduced, and the traditional Chinese medicine intervention group can obviously recover the levels of the three hormones.
Due to thyroxine T3、T4Can significantly improve the basal metabolic level of the body, while testosterone (T) can promote the synthesis of protein, so the data in Table 1 and Table 2 can be combinedThe traditional Chinese medicine extract is presumed to cause the reduction of the body mass and the percentage of visceral fat, and has close relation with the traditional Chinese medicine extract which improves the metabolic level of the organism and promotes the synthesis of protein.
Example 6
In the embodiment, the weight-losing effect observation of the weight-losing meal replacement powder for improving the basal metabolism level on obese people is also provided.
A total of 62 patients with obesity of 20-35 years old are selected, patients with hypertension and serious cardiovascular and cerebrovascular diseases are excluded, informed consent is signed on the basis of patient volunteering, and the patients are randomly divided into a control group and a weight-losing meal replacement group according to the Body Mass Index (BMI), wherein each group comprises 32 patients. Wherein, 13 men and 19 women in the control group have average age (31.3 + -2.1) and average height (169.7 + -6.3) cm; the average age (30.8 +/-2.8) of the test group male and the average height (168.9 +/-5.2) of the test group female are 15, and the average height and the average age of the test group male are 168.8 +/-2.8 cm. On the basis of health education, 20g of protein meal replacement powder of a certain brand is given to a control group to replace dinner every day, 20g of weight-reducing meal replacement powder trial prepared in example 3 is given to a test group to replace dinner every day, no limitation is caused on breakfast and lunch, and continuous intervention is carried out for 6 weeks. The height, weight and visceral fat area were measured with a body composition meter before and after intervention, while the BMI was automatically calculated by the meter from the height and weight, detailed results are shown in table 3.
TABLE 3 Effect of diet meal replacement powder on body weight and visceral fat area
Note: compared to pre-intervention,: p is a radical of<0.05; compared with the control group, the compound of the formula,#:p<0.05。
as can be seen from the data in Table 3, after 6 weeks of intervention, the body weight, BMI and visceral fat area decreased in both groups, with the average decrease in body weight of 7.8Kg and the average decrease in BMI of 2.8 Kg/m in the test group2Average decrease in visceral fat area of 18.0cm2Are obviously higher than the control group, which shows that the trial-produced meal replacement powder with the function of improving the basal metabolic rate is higher than the common proteinThe meal replacement powder has more remarkable effects of reducing body weight and visceral fat area.
Example 7
This example provides a typical weight-reducing case of a trial-produced meal replacement powder
Miss Liu, age 29, accounting company, weight obviously increased after two births produced three years ago, weight-losing consultation was carried out from 10 months in 2019 to a certain health management center, and after measurement by a body composition meter, the height of the patient was 1.61cm, the weight of the patient was 79.8Kg, the waist length of the patient was 92cm, and the BMI was 30.8Kg/m2The visceral fat area is 134.6cm2. Under the guidance of workers, by improving the dietary structure, enhancing the exercise and replacing one supper with the meal replacement powder trial prepared in example 3 for improving the basal metabolic rate every night, a certain sense of hunger is generated 9 o' clock in the evening after the beginning of a week, and the sense of hunger is obviously reduced in the evening after half a month when half an apple (about 125g) is eaten under the guidance of the workers. Then the meal at 9 o' clock in the evening is removed, the meal replacement is continued, and after the meal replacement at 6 th week is finished, the weight is reduced to 71.9Kg, the waist is 87cm, the BMI is reduced to 27.7Kg, and the visceral fat area is reduced to 118.4cm2And the body feels relaxed obviously, and the mental state is improved obviously. After the intervention is finished, the healthy life style is continuously maintained, and no obvious rebound exists within 3 months. The meal replacement powder for improving basal metabolic rate, which is prepared in example 3 and is tried out for 6 weeks from 2 months in 2020, is used for replacing one dinner, and the weight of the meal replacement powder is continuously reduced to 67.1Kg, the waist circumference is 84cm, the BMI is reduced to 25.9, and the visceral fat area is reduced to 103.7cm from 4 middle days in 20202The body shape and mental state are further improved, and the weight loss process is particularly satisfied.
In conclusion, the incidence of overweight and obesity is high, and long-term overweight and obesity are important risk factors leading to cardiovascular and cerebrovascular diseases, diabetes and osteoporosis. Meal replacement weight reduction is a very popular weight reduction mode, but the basic metabolic rate is obviously lower than that of a normal person due to the fact that the secretion levels of endocrine hormones such as thyroxine and testosterone of most obese people are low, so that the basic metabolic rate is improved due to the fact that the secretion level of the endocrine hormones cannot be obviously improved when a person is subjected to meal replacement weight reduction, and therefore the weight reduction effect is not obvious and is easy to rebound.
On the basis of the previous research, the invention firstly uses the traditional Chinese medicine with medicine and food homology to improve the secretion level of hormone so as to improve the basic metabolic rate of an organism, wherein ginseng (the main effective component is ginsenoside) can improve the metabolic level and the resistance of the organism; the combined application of onion, dried ginger and cinnamon can stimulate the metabolism function of the organism and promote thyroxine T3、T4The combined application of the purple perilla and the sea buckthorn can promote lipolysis and reduce blood fat, reduce the risk of cardiovascular and cerebrovascular diseases while reducing fat and weight, reduce blood fat of mulberry leaves (main components of nojirimycin), inhibit starch decomposition and reduce postprandial blood sugar, and reduce the blood fat and the blood sugar level of the seeds of shinyleaf yellowhorn, the seeds of beautiful yellowhorn and the leaves of beautiful liana fruit.
According to the invention, the metabolism of the organism is improved by the traditional Chinese medicine extract, and the decomposition and absorption of carbohydrates are delayed by matching with dietary fibers and oligosaccharides on the basis, wherein beta-glucan contained in oat fibers can also improve the immunity of the organism, konjac fibers have a strong moisture absorption function and can slow down the emptying of the stomach to relieve hunger sensation, and the white kidney bean extract and the L-arabinose can respectively inhibit amylase and sucrase to reduce the generation speed of glucose in the small intestine, so that the absorption of energy is reduced and the weight-losing effect is achieved;
inulin and fructo-oligosaccharide, L-arabinose and galacto-oligosaccharide which are used as soluble dietary fibers can delay the absorption of glucose and improve intestinal flora, thereby reducing insulin resistance, improving the metabolism of organisms to reduce blood sugar and improve the symptoms of diabetes, and medium-chain fatty acid contained in medium-long-chain fatty acid and coconut oil powder can be directly combusted in the liver and is not easy to store in the body while providing energy; whey protein and soybean protein isolate as high-quality protein from animals and plants can prevent loss of skeletal muscle protein in meal replacement process, and appropriate amount of supplement of vitamins and minerals can improve organism metabolic process and prevent loss of skeletal minerals. In particular, the addition of N-acetylneuraminic acid (also known as cubilose acid, sialic acid) and guarana extract to the composition is because cubilose acid can promote the synthesis of collagen in the skin, increase the moisture and elasticity of the skin, and make the skin more glossy [ green build, tangy base, chuanfang, etc.. compared with the activities of antioxidation and promotion of epidermal cell growth of cubilose extract, 2019,45 (17): 73-78], thereby leading people not to loose and lose elasticity of skin while losing weight, and meeting the psychological needs of young women for losing weight; a large amount of research evidence shows that the guarana does not have any addiction, is a food natural spice which is legally added in the food additive standard of China (the food safety national standard food additive use standard (GB 2760 + 2014)), and has the effects of improving the excitability of central nerves, improving the basal metabolic rate, and quickly recovering physical fatigue [ Shenguo, Yetian, Zhouyang, and the like ].
Therefore, the compound weight-losing and sugar-reducing compound with the function of improving the basic metabolism can accurately regulate and control the main factors causing obesity and diabetes from multiple aspects, has good effects of quickly losing weight without hunger and preventing rebound, is beneficial to keeping tight and bright skin in the weight-losing process, and can obviously inhibit postprandial blood sugar and improve the symptoms of diabetes for diabetic patients.
Most of the Chinese herbal medicines used in the meal replacement composition capable of improving the basal metabolic rate and the insulin sensitivity of the organism belong to the category of medicine-food homologous and new food raw materials, other meal replacement raw materials also belong to the category of food essentially, and the processing technology also belongs to the processing technology of food, so that the composition hardly has toxic or side effect within a normal dosage range, and the safety of the composition is ensured from the source. On the basis, the taste of the composition is adjusted by food additives such as a sweetening agent, an acidulant and the like to cover the special taste of the traditional Chinese medicine, so that the composition can be made into meal replacement powder or solid beverage, thereby being accepted by most people and being easy to popularize in a large area to generate great economic benefit and social benefit. Meanwhile, after the composition is used for successfully reducing weight, the morbidity risk of cardiovascular and cerebrovascular diseases is also reduced, so that greater health benefits are generated.
The above description is only a preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the present invention, and all changes and modifications that come within the meaning and range of equivalency of the specification are intended to be embraced therein.
Claims (9)
1. A meal replacement composition for increasing basal metabolic levels, comprising: the composition comprises the following raw materials in parts by weight: 3-4 parts of dietary fiber, 4-5 parts of oligosaccharide, 3-5 parts of protein powder, 3-5 parts of fatty acid powder, 1-4 parts of traditional Chinese medicine extract powder, 0.5-1.5 parts of white kidney bean extract, 0.5-1.5 parts of guarana extract, 0.01-0.1 part of cubilose acid powder, 0.02-0.05 part of compound vitamin and 0.3-0.7 part of compound mineral substance;
the traditional Chinese medicine extract powder comprises the following raw materials in parts by weight: 2-3 parts of ginseng, 1-2 parts of onion, 1-3 parts of sea buckthorn, 1-2 parts of dried ginger, 1-2 parts of purple perilla, 2-3 parts of citrus young fruit, 1-2 parts of cinnamon, 2-3 parts of mulberry leaf, 2-3 parts of shinyleaf yellowhorn and 2-3 parts of plukenetia volubilis.
2. The meal replacement composition for increasing basal metabolic level according to claim 1, wherein: the dietary fiber comprises the following raw materials in parts by weight: 1-3 parts of oat fiber, 1-3 parts of konjac fiber and 2-4 parts of inulin; the oligosaccharide comprises the following raw materials in parts by weight: 1-3 parts of fructo-oligosaccharide, 0.5-2 parts of L-arabinose and 0.5-2 parts of galacto-oligosaccharide.
3. The meal replacement composition for increasing basal metabolic level according to claim 1, wherein: the protein powder comprises the following raw materials in parts by weight: 2-4 parts of whey protein powder and 2-4 parts of soybean protein isolate powder;
the fatty acid powder comprises the following raw materials in parts by weight: 1-3 parts of medium-long chain fatty acid powder, 1-3 parts of safflower seed oil powder and 1-3 parts of coconut oil powder.
4. The meal replacement composition for increasing basal metabolic level according to claim 1, wherein: the compound vitamin comprises the following raw materials in parts by weight: 0.2-0.5 part of beta-carotene, 0.4-0.7 part of retinyl acetate, 10-15 parts of thiamine hydrochloride, 10-15 parts of riboflavin, 12-18 parts of nicotinic acid, 2-5 parts of D-calcium pantothenate, 10-15 parts of pyridoxine hydrochloride, 0.1-0.3 part of folic acid, 0.002-0.005 part of cyanocobalamin, 10-15 parts of cholecalciferol and 8-12 parts of dl-alpha-tocopherol acetate; the composite mineral comprises 10-15 parts of magnesium gluconate, 0.5-2 parts of zinc gluconate, 20-30 parts of calcium carbonate and 0.5-2 parts of selenium yeast.
5. The meal replacement composition for increasing basal metabolic level according to claim 2, wherein: preferably, the meal replacement composition comprises the following raw materials in parts by weight: 2-3 parts of oat fiber, 2-3 parts of konjac fiber, 2-3 parts of inulin, 2-5 parts of fructo-oligosaccharide, 1-2 parts of L-arabinose, 1-2 parts of galacto-oligosaccharide and 2-3 parts of whey protein powder;
the feed also comprises 2-3 parts of soybean protein isolate powder, 1-3 parts of medium-long chain fatty acid powder, 1-2 parts of safflower seed oil powder, 1-2 parts of coconut oil powder, 2-4 parts of traditional Chinese medicine extract powder, 0.5-1 part of white kidney bean extract, 0.5-1.5 parts of guarana extract, 0.03-0.06 part of cubilose acid powder, 0.003-0.006 part of compound vitamin and 0.07-0.09 part of compound mineral substance.
6. A preparation method of meal replacement composition for improving basal metabolism level is characterized by comprising the following steps: the method comprises the following steps:
1) preparing medicinal and edible Chinese medicinal composite extract powder;
2) compounding the dietary fiber, the oligosaccharide, the protein powder, the fatty acid powder, the white kidney bean extract, the cubilose acid powder, the compound vitamin and the compound mineral substance;
3) the taste is adjusted to form meal replacement powder or meal replacement solid beverage;
4) adding into food raw materials to prepare meal replacement bar, meal replacement chocolate, meal replacement biscuit or meal replacement soft candy;
the preparation method of the traditional Chinese medicine extract powder comprises the following steps: weighing ginseng (artificially planted for less than five years), onion, sea buckthorn, dried ginger, purple perilla, citrus immature fruit, cinnamon, mulberry leaf, shinyleaf yellowhorn and plukenetia volubilis fruit in proportion, crushing the composition to 20-30 meshes, adding 15 times of purified water, decocting for 1-2 h, repeatedly decocting for three times, combining decoction, concentrating under reduced pressure, and spray drying to obtain the traditional Chinese medicine extract powder.
7. The method of preparing a meal replacement composition for increasing basal metabolic levels of claim 6, wherein: the method also comprises the steps of fully and uniformly mixing the dietary fibers, the oligosaccharides, the protein powder, the fatty acid powder, the white kidney bean extract, the guarana extract, the bird's nest acid powder and the traditional Chinese medicine extract powder, and then adding the sweetening agent and the acidity regulator to prepare meal replacement powder or meal replacement solid beverage, or adding the sweetening agent and the acidity regulator to food raw materials to prepare meal replacement bars or meal replacement chocolates or meal replacement biscuits or meal replacement soft sweets.
8. The meal replacement composition for increasing basal metabolic level according to claim 1, wherein the meal replacement composition is used for weight-reducing and lipid-lowering meal replacement and diabetes meal replacement.
9. The use of a meal replacement composition for increasing basal metabolic levels according to claim 8, wherein: the composition also comprises powder, and the prepared powder is subpackaged into 10-25 g; the powder can be used as meal replacement powder to replace 1 supper per day, or used as solid beverage before meal to reduce meal consumption of lunch and supper.
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