CN101711840B - Medicine-food dual-purpose composition suitable for cancerous patients and preparation method thereof - Google Patents
Medicine-food dual-purpose composition suitable for cancerous patients and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a medicine-food dual-purpose composition suitable for cancerous patients, which comprises Chinese yam, astragalus root, prepared rehmannia root, semen coicis, medlar, hawthorn, lily, lotus seed, red date, Jew's-ear, vitamin A and vitamin C. The medicine-food dual-purpose composition can be processed and prepared into granules, oral liquid, fluid foods or semifluid foods. The medicine-food dual-purpose composition takes natural Chinese herbal medicines as main raw materials, has reasonable formula and comprehensive nutrition, has the functions of suppressing tumours and enhancing the immunity of an organism, can be taken for a long time, provides relatively ideal medicines and/or foods for the cancerous patients and is especially suitable for postoperative patients to eat.
Description
Technical field
The present invention relates to a kind of medicine-food dual-purpose composition, relate in particular to a kind of cancer patient's of being applicable to postoperative or daily edible medicine-food dual-purpose composition and preparation method thereof.
Background technology
In recent years, the sickness rate of malignant tumor rises year by year.According to World Health Organization's statistics, the whole world has 7,000,000 people to die from tumor every year approximately at present.Reduce the M ﹠ M of cancer, effective control of further strengthening cancer is the core content of whole world cancer research.
Cancer patient's nutriture quality directly affects the antineoplaston effect.Bibliographical information, cancer patient's malnutrition incidence rate is 40%～75%.With malnutrition, about 40% cancer patient is died from malnutrition to most of malignant tumor patient when making a definite diagnosis, and is not to be cancer itself and treatment factor.This mainly is because the cancer patient is because the effect of the toxicant that the tumor metabolism produces causes that the patient has the full early symptom of anorexia in early days.In addition, to treatment for cancer, as surgical operation, chemotherapy or radiotherapy etc. when killing and wounding cancerous cell, also can cause destruction to immunologic function, the capital produces untoward reaction to the patient, as anorexia, abnormal flavour sense, abdominal distention, constipation, diarrhoea, xerostomia, pharyngolaryngitis, nausea and vomiting etc., all these symptoms all can influence patient's appetite; In addition, heating can further be quickened the effect of body catabolism as common reactant after postoperative or the medication, causes malnutrition gradually.Arrived cancer of late stage, low albumen, anemia, fever, infection also can make patient's inappetence, and feed reduces, weight loss; The while patient often has the phenomenon of anxiety, fear, disappointment, depression, effectively supports and adjusting if lack, and can cause that also loss of appetite causes nutrition intake minimizing in various degree.Therefore, malnutrition is the FAQs during cancer diagnosis and the anticancer therapy.
Malnutrition can cause the T lymphocyte number to reduce, reduce the activity of natural killer cell and IL-2, weaken the B cell function, delay the reaction of body to sensitizing antigen, change the vigor of kytoplasm, thereby weaken neutrophilic granulocyte to the engulfing and lethal effect of antibacterial, this is very unfavorable to patient's system of defense, make the patient be difficult to the influence of tolerate surgery, radiotherapy or chemotherapy, easily cause poor wound healing body; Simultaneously, malnutrition easily makes the patient feel tired, and the activity that can not participate in liking, and the possibility of becoming thin and will constantly remind the existence and the death of patient disease of body, easily cause negative psychology, increase mental pressure etc.These situations all can influence the treatment to the patient, are unfavorable for lapsing to of disease.
Nutriture is the important indicator of indication disease quality, and patient also only can bear cancer or chemotherapy to all pressure of health under good nutriture.And the underfed main cause of cancer patient is exactly that dietary structure is unreasonable, nutrition intake deficiency etc.
Therefore, be necessary to study and a kind ofly can satisfy cancer patient's nutritional need, and have simultaneously and suppress tumor, human body immunity improving power, patient and be easy to the medicine-food dual-purpose composition accepting and have no side effect.
Summary of the invention
The purpose of this invention is to provide the medicine-food dual-purpose composition that a kind of suitable cancer patient eats, it comprises following raw material: RHIIZOMA DIOSCOREAE frOm Henan of China, the Radix Astragali, Radix Rehmanniae Preparata, Fructus Lycii, Semen Coicis, Fructus Crataegi, Semen Nelumbinis, Bulbus Lilii, Fructus Jujubae, Auricularia, vitamin A and vitamin C.
Wherein, the weight portion of described medicine-food dual-purpose composition raw material is as follows: RHIIZOMA DIOSCOREAE frOm Henan of China 20-30, Radix Astragali 5-15, Radix Rehmanniae Preparata 5-15, Semen Coicis 3-10, Fructus Lycii 3-10, Fructus Crataegi 15-30, Bulbus Lilii 5-30, Semen Nelumbinis 5-20, Fructus Jujubae 5-20, Auricularia 10-20, vitamin A 0.01-0.03, vitamin C 1-3;
Preferably, the weight portion of described medicine-food dual-purpose composition raw material is as follows: RHIIZOMA DIOSCOREAE frOm Henan of China 20, the Radix Astragali 15, Radix Rehmanniae Preparata 15, Semen Coicis 10, Fructus Lycii 10, Fructus Crataegi 15, Bulbus Lilii 5, Semen Nelumbinis 5, Fructus Jujubae 5, Auricularia 10, vitamin A 0.02, vitamin C 2;
More preferably, the weight portion of described medicine-food dual-purpose composition raw material is as follows: RHIIZOMA DIOSCOREAE frOm Henan of China 25, the Radix Astragali 10, Radix Rehmanniae Preparata 10, Semen Coicis 8, Fructus Lycii 8, Fructus Crataegi 20, Bulbus Lilii 20, Semen Nelumbinis 10, Fructus Jujubae 10, Auricularia 15, vitamin A 0.01, vitamin C 1.
In addition, for improving mouthfeel, medicine-food dual-purpose composition of the present invention also comprises sweeting agent, and its weight portion is 1-3.
Another object of the present invention provides the preparation method of described medicine-food dual-purpose composition, takes by weighing above-mentioned raw materials according to described weight portion, can make granule, oral liquid, supping or semi-fluid food etc., and is edible for the cancer patient.
The preparation method of described medicine-food dual-purpose composition granule comprises the steps:
1) get the Radix Astragali, Radix Rehmanniae Preparata, Semen Coicis, the Fructus Lycii of described weight portion, pulverize, mix, add 6-10 times of water gaging, heating extraction 45 minutes-1.5 hours is extracted 3 times, merge extractive liquid,, and filtration, filtrate decompression is concentrated into the clear paste that relative density is 1.25-1.4;
2) get RHIIZOMA DIOSCOREAE frOm Henan of China, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae, the Auricularia of described weight portion, pulverize, join in the above-mentioned clear paste with vitamin A, vitamin C, add sweeting agent again, mixing is granulated, and drying is sieved, and granule is made in packing.
The preparation method of described medicine-food dual-purpose composition oral liquid comprises the steps:
1) gets RHIIZOMA DIOSCOREAE frOm Henan of China, the Radix Astragali, Radix Rehmanniae Preparata, Semen Coicis, Fructus Lycii, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae, the Auricularia of described weight portion, pulverize, mix, add 6-10 times of water gaging, heating extraction 45 minutes-1.5 hours is extracted merge extractive liquid, 3 times, filter, filtrate decompression is concentrated into the concentrated solution that relative density is 1.1-1.2, adds 60% ethanol of 2 times of amounts, leaves standstill, get supernatant liquid filtering, filtrate decompression is concentrated into the concentrated solution that relative density is 1.1-1.2;
2) add vitamin A, vitamin C, citric acid, sweeting agent, add water and be made into medicinal liquid, fill, oral liquid is made in sterilization.
The preparation method of described medicine-food dual-purpose composition nutrient porridge comprises the steps:
1) get the Radix Astragali, the Radix Rehmanniae Preparata of described weight portion, pulverize separately adds 6-10 times of water gaging, and heating extraction 45 minutes-1.5 hours is extracted 3 times, and merge extractive liquid, filters, and obtains Radix Astragali extract and Radix Rehmanniae Preparata extract;
2) RHIIZOMA DIOSCOREAE frOm Henan of China, Semen Coicis, Fructus Lycii, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae of getting described weight portion cleaned and placed pot, adds 10 times of water gagings, soaks after 30 minutes, heat endure ripe;
3) add Radix Astragali extract and the Radix Rehmanniae Preparata extract that step 1) makes, and Auricularia, vitamin A, vitamin C, continue to be brewed into pasty state, add sweeting agent, cooling promptly gets nutrient porridge.
Wherein, described sweeting agent comprises Icing Sugar, xylitol, sucralose, stevioside, Mel, crystal sugar or its combination.
In the raw material of medicine-food dual-purpose composition of the present invention:
RHIIZOMA DIOSCOREAE frOm Henan of China has the edibility of higher nutritive value, medical value and science.Its nature and flavor are sweet flat, return spleen, lung, kidney channel, and main effect is: supplementing QI and nourishing YIN, spleen reinforcing lung kidney.Modern chemistry and pharmaceutical research are found, RHIIZOMA DIOSCOREAE frOm Henan of China contains multiple compositions such as crude fibre, pectin, amylase, phlegmatic temperament glycoprotein, saponin, Rhizoma Dioscoreae element, choline, fatty acid, polysaccharide, also contains the indispensable trace element of human body such as iodine, calcium, ferrum and phosphorus; Its pharmacological action can be used as the auxiliary health food and/or the medicine of antineoplastic agent and chemotherapy for regulating spleen and stomach function, antioxidation, adjusting immunity, blood sugar regulation, antitumor etc.
The Radix Astragali belongs to nourishing class Chinese crude drug, slightly warm in nature, and sweet in the mouth is returned spleen, lung meridian, has tonifying Qi and lifting yang, benefit to defend the effect of consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.In recent years the main chemical compositions that studies show that the Radix Astragali has astragalus polysaccharides, saponins, flavonoid and aminoacid etc.; Its pharmacological action is for having the raising immunologic function; strengthen antioxidation, radioprotective and antitumaous effect, protection cardiovascular and cerebrovascular vessel, liver, kidney and lungs effect, protection brain cell, improving memory; antibiotic and suppress virus function, effects such as blood fat reducing, blood sugar lowering, minimizing diabetic complication.Mainly be to use the Radix Astragali to improve body's immunological function at present clinically, protection and promotion bone marrow hematogenesis ability, the enhance immunity cell kills tumor activity.
Radix Rehmanniae Preparata is the process of preparing Chinese medicine processed goods (stewed with wine or wine steam method) of Radix Rehmanniae tuber, is the traditional excellent tonic product of China.Merit is arrogated to oneself the YIN nourishing of enriching blood, and beneficial essence is filled out marrow, is the key medicine of the cloudy blood of nourishing the liver and kidney.Modern pharmacology studies show that, it has the propagation that promotes hematopoietic cell, improves effects such as immunity, blood sugar lowering, antitumor.
Fructus Lycii is a common food, is again traditional drug; The property flat, sweet in the mouth, have the effect of nourishing the liver and kidney, replenishing vital essence to improve eyesight, contain abundant lycium barbarum polysaccharide, fat, protein, free amino acid, taurine, betanin, vitamin B
1, vitamin B
2, vitamin E, vitamin C, particularly carotenoid content be very high.Modern clinically be widely used in defying age, blood fat reducing, protect the liver, aspects such as blood sugar lowering and human body immunity improving, antitumor.
Semen Coicis is called as the top grade medicine that nourishes heart in Compendium of Material Medica.Slightly sweet flavor, cold nature is returned spleen, stomach, lung meridian, the spleen invigorating of function dampness removing, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.Contained main pharmacological component is fatty acid and fat in the Semen Coicis, also contains sterols, triterpenes, polysaccharide compound and protein, aminoacid and vitamins and other nutritious components in addition.Have blood pressure lowering, blood sugar lowering and anti-inflammatory and antalgic, antitumor, immunomodulating, antiviral effect.
Fructus Crataegi is traditional simply digestants, and spleen, stomach, Liver Channel are gone in sweet in the mouth, slightly warm in nature acid; The function appetite-stimulating indigestion-relieving, invigorating the spleen and benefiting QI; Very high nutrition and medical value are arranged, and often eating haw products can appetite strengthening.Modern study shows the generation that free radical could be blocked and reduce to flavonoid that it is contained and materials such as vitamin C, carotene, and immunity that can enhancing body has anti-aging, anticancer effect.
Semen Nelumbinis are the all-ages delicious excellent tonic product of generally acknowledging since ancient times.Nature and flavor are sweet equals, has spleen reinforcing antidiarrheal, supplementing the kidney to control the nocturnal, effects such as tranquilizing by nourishing the heart.Semen Nelumbinis also contain cupreol except that containing a large amount of starch, minerals and vitamins such as alkaloid and the calcium that enriches, phosphorus, ferrum.Calmness, heart tonifying, the anti-ageing multiple effect of waiting for a long time are arranged.
Auricularia is a kind of self-sow or the fungus of artificial culture on various rotten wood, has high nutritive value and medical value, is described as " meat or fish in the element " and " king in the element " by nutritionist, has effects such as lung heat clearing, lung moistening, vigorate qi and replenish the blood.Contain protein, fat, calcium, carbohydrate, phosphorus, ferrum, carotene, vitamin B
1, contain a large amount of fibers, potassium, magnesium and sodium etc. in addition.Polysaccharide in the modern medicine proof Auricularia has enhancing body immunity, effects such as cancer-resisting.
The Bulbus Lilii sweet and slightly bitter taste, property is flat, goes into the cardiopulmonary warp; Has the disappear effect of heat, clearing away heart-fire for tranquillization of nourishing the lung to arrest cough, yin nourishing.It contains starch, protein, fat and calcium, phosphorus, ferrum, vitamin B
1, B
2, multiple nutritional components such as C, have the merit of good nutritious tonifying, weakling after being ill is highly profitable.
Fructus Jujubae sweet in the mouth, property are put down, and go into spleen, stomach warp; Strengthen the spleen and stomach yin and blood nourishing, tranquilizing by nourishing the heart, the effect of the mitigation property of medicine; Can improve body immunity, but and anticancer, the people of body void is after being ill also had good tonic effect.
The major function of vitamin A is to keep the epithelial tissue normal configuration, stimulates body immune system, transfers the anticancer enthusiasm of body, resists carcinogenic intrusion.The intercellular substance of malignant growth Gonna breakthrough, vitamin C then participates in the structure of intercellular substance, and its barrier action can be protected the intercellular substance structural integrity, and vitamin C is the generation of inferior ammonium nitrate capable of blocking also, thereby plays protective effect on cancer risk.Therefore, in medicine-food dual-purpose composition prescription of the present invention, a certain amount of vitamin A, C have also been added.
In sum, under the guidance of Chinese medical theory, the present invention is directed to the problem that prior art exists, a kind of nutritional labeling equilibrium is provided, is fit to the daily edible medicine-food dual-purpose composition of cancer patient.Medicine-food dual-purpose composition of the present invention possesses flat benefit of negative and positive and not dry, the characteristics that QI invigorating is enriched blood and combined; And compared with prior art, raw material of the present invention is mainly natural plant, and cost is lower; Behind the edible for patients, can improve the nutriture of self, improve toleration, certain facilitation is played in rehabilitation treatment.Functional trial is the result show: this product can be assisted the inhibition tumor cell, has the effect that suppresses tumor growth, enhancing human body immunity function, and has no side effect.
Medicine-food dual-purpose composition of the present invention is primary raw material with the natural Chinese medicinal herb, and prescription is reasonable, comprehensive nutrition, has the effect that suppresses tumor, human body immunity improving power, can take for a long time,, be particularly suitable for postoperative patient and eat for the cancer patient provides a kind of comparatively ideal medicine and/or food.
The specific embodiment
Following specific embodiment only is used for that the present invention will be further described, does not represent limiting the scope of the invention.
The preparation of the granule of embodiment 1 medicine-food dual-purpose composition of the present invention
Get RHIIZOMA DIOSCOREAE frOm Henan of China 25kg, Radix Astragali 10kg, Radix Rehmanniae Preparata 10kg, Semen Coicis 8kg, Fructus Lycii 8kg, Fructus Crataegi 20kg, Bulbus Lilii 20kg, Semen Nelumbinis 10kg, Fructus Jujubae 10kg, Auricularia 15kg, vitamin A 0.01kg, vitamin C 1kg, make granule according to following step:
1) with the Radix Astragali, Radix Rehmanniae Preparata, Semen Coicis, Fructus Lycii pulverizing medicinal materials, cross sieve No. 2, mix, add 10 times of water gagings, soaked heating extraction 1.5 hours 30 minutes; For the second time add 8 times of water gagings, extracted 1 hour; Add 6 times of water gagings for the third time, extracted 45 minutes; Merge 3 times extracting solution, leave standstill, filter, filtrate decompression is concentrated into the clear paste that relative density is 1.25-1.4;
2) RHIIZOMA DIOSCOREAE frOm Henan of China, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae, black fungus powder are broken into fine powder, cross sieve No. 6, join in the above-mentioned clear paste with vitamin A powder, vitamin c powder, add the 1kg stevioside again, mixing is granulated, and drying is crossed 14 mesh sieves, and granule is made in packing.
The preparation of the oral liquid of embodiment 2 medicine-food dual-purpose compositions of the present invention
Get RHIIZOMA DIOSCOREAE frOm Henan of China 200g, Radix Astragali 150g, Radix Rehmanniae Preparata 150g, Semen Coicis 100g, Fructus Lycii 100g, Fructus Crataegi 150g, Bulbus Lilii 50g, Semen Nelumbinis 50g, Fructus Jujubae 50g, Auricularia 100g, vitamin A 0.2g, vitamin C 20g, make oral liquid according to following step:
1) RHIIZOMA DIOSCOREAE frOm Henan of China, the Radix Astragali, Radix Rehmanniae Preparata, Semen Coicis, Fructus Lycii, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae, black fungus powder are broken into coarse powder, cross sieve No. 2, mix, add 10 times of water gagings, soaked heating extraction 3 times 30 minutes, each 1 hour, merge extractive liquid, filtered, filtrate is concentrated into the concentrated solution that relative density is 1.1-1.2, add 60% ethanol of 2 times of amounts, stir evenly, left standstill 24 hours, get supernatant liquid filtering, filtrate decompression is concentrated into the concentrated solution that relative density is 1.1-1.2;
2) add vitamin A powder, vitamin c powder, citric acid 20g, xylitol 30g, sucralose 30g, add the medicinal liquid that water is made into 10L, fill, oral liquid is made in sterilization.
The preparation of the nutrient porridge of embodiment 3 medicine-food dual-purpose compositions of the present invention
Get RHIIZOMA DIOSCOREAE frOm Henan of China 30g, Radix Astragali 5g, Radix Rehmanniae Preparata 5g, Semen Coicis 3g, Fructus Lycii 3g, Fructus Crataegi 30g, Bulbus Lilii 30g, Semen Nelumbinis 20g, Fructus Jujubae 20g, Auricularia 20g, vitamin A 0.03g, vitamin C 3g, make nutrient porridge according to following step.
1) get the Radix Astragali, the Radix Rehmanniae Preparata of described weight portion, pulverize separately adds 8 times of water gagings, heating extraction 3 times, and each 1.5 hours, merge extractive liquid, filtered, and obtains Radix Astragali extract and Radix Rehmanniae Preparata extract;
2) RHIIZOMA DIOSCOREAE frOm Henan of China, Semen Coicis, Fructus Lycii, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae cleaned placed pot, add 10 times of water gagings, soaks after 30 minutes, heat endure ripe;
3) add above-mentioned Radix Astragali extract and Radix Rehmanniae Preparata extract, and black fungus powder, vitamin A powder, vitamin c powder, continue to be brewed into pasty state, add proper honey, crystal sugar, promptly get nutrient porridge after the cooling.
The research of experimental example 1 function assessment
The present invention is to provide the medicine-food dual-purpose composition that a kind of suitable cancer patient eats, for proving that it has the function that suppresses tumor, regulates immunity, the granule (hereinafter referred to as granule of the present invention) that the inventor adopts embodiment 1 to prepare has carried out the function assessment test, and result of the test is as follows:
1. to the influence of mouse thymus and spleen
Method: (male and female half and half, body weight 18～22g) are divided into 5 groups at random, each 10 with Kunming mouse.Wherein 4 groups (removing the blank group) be whole intraperitoneal injection of cyclophosphamide (CY) 80mg/kg when the experiment beginning, every 1 time on the 2nd, totally 2 times, the granule aqueous solution of the present invention, the lentinan film suspension that gavage high and low dose respectively reach with the volume distilled water administration every day 1 time; Blank group normal diet is fed.Eyeball is got blood examination and is looked into peripheral blood leucocyte and erythrocyte after 7 days, separates thymus and spleen after putting to death animal, inhales on the rearmounted balance of branch that anhydrates with filter paper and weighs, and the result sees Table 1 respectively, table 2.(experimental data is checked with t and is carried out statistical analysis)
Table 1 granule of the present invention is to peripheral blood leucocyte and erythrocytic effect
Annotate: with the model group ratio,
*P＜0.05,
*P＜0.01.
Table 2 granule of the present invention is to the effect of spleen and thymus
Annotate: with the model group ratio,
*P＜0.05.
The result shows: through the cyclophosphamide lumbar injection after 7 days, mouse spleen and thymic weight obviously reduce, granule of the present invention can be protected spleen and the thymus of immunologic hypofunction mice, makes spleen and thymus can keep weight obvious decline not occur under the cyclophosphamide effect; In addition, granule of the present invention also has the effect of rising peripheral blood leucocyte.
2. to the influence of immunosuppressed mice peritoneal macrophage phagocytic function
(male and female half and half, body weight 18～22g) are divided into 5 groups at random, each 10 with Kunming mouse.Wherein make CY immunocompromised model (dosage is 80mg/kg for 4 groups, 1st, 2,3 days continuous lumbar injections), 4 groups of granule aqueous solution of the present invention, lentinan film suspensions that gavage high and low dose respectively of modeling type reach with the volume distilled water, administration every day 1 time, continuous 8 days, other establishes 1 group was complete blank group.1h after last 1 administration injects 5% chicken red blood cell normal saline suspension 0.4ml/ only to mouse peritoneal, and 4h after giving chicken red blood cell puts to death mice, gets peritoneal fluid, hatches, dyeing, microscopy and calculate phagocytic percentage and phagocytic index, the results are shown in Table 3.
Table 3 granule of the present invention causes the influence (X ± S) of immunocompromised Turnover of Mouse Peritoneal Macrophages phagocytic function to CY
Annotate: with the model group ratio,
*P＜0.05,
*P＜0.01.
The result shows: model group obviously reduces than blank group phagocytic percentage and phagocytic index, and the modeling success is described.With the model group ratio, high and low dose granule group of the present invention all can significantly improve immunosuppressed mice peritoneal macrophage phagocytic percentage and phagocytic index.
3. to inoculation S
180The influence of sarcoma mice
(male and female half and half, body weight 18～22g) are divided into 3 groups (high and low dose administration group, matched groups) at random, each 16 with mice.In every Mus right lower extremity subcutaneous vaccination S
180Sarcoma cell 1 * 10
6/ 0.2ml, tumor incidence rate 100%.Since the 2nd day, gavage the granule aqueous solution of the present invention of high and low dose respectively, matched group gives the equivalent distilled water, every day 1 time, continuous 8 days.Respectively at the 1st, 5 and 10 day execution mice after the drug withdrawal, strip out the tumor piece and weigh.Observe the tumor piece weight change of 3 groups of mices, the results are shown in Table 4.
Table 4 granule of the present invention is to S
180The inhibitory action of tumor growth (X ± S)
The result shows: granule of the present invention can obviously suppress tumor growth, uses back early stage obviously (P＜0.05).
In sum, the generation of tumor is closely related with modulation on immune status, immunodeficiency or low easily induced tumor; And cancer patient's (radiotherapy, chemotherapy etc.) in therapeutic process exists serious side effects such as suppressing body's immunity.Show by test, medicine-food dual-purpose composition of the present invention has certain inhibition tumor growth, the effect of enhancing human body immunity function, it also contains rich nutrient substances simultaneously, can improve the underfed situation of patient, relatively is fit to the cancer patient and takes for a long time.
Claims (8)
1. medicine-food dual-purpose composition that is applicable to the cancer patient, it is characterized in that, make: RHIIZOMA DIOSCOREAE frOm Henan of China 20-30, Radix Astragali 5-15, Radix Rehmanniae Preparata 5-15, Semen Coicis 3-10, Fructus Lycii 3-10, Fructus Crataegi 15-30, Bulbus Lilii 5-30, Semen Nelumbinis 5-20, Fructus Jujubae 5-20, Auricularia 10-20, vitamin A 0.01-0.03, vitamin C 1-3 by the raw material of following weight portion.
2. medicine-food dual-purpose composition according to claim 1, it is characterized in that the weight portion of described raw material is as follows: RHIIZOMA DIOSCOREAE frOm Henan of China 25, the Radix Astragali 10, Radix Rehmanniae Preparata 10, Semen Coicis 8, Fructus Lycii 8, Fructus Crataegi 20, Bulbus Lilii 20, Semen Nelumbinis 10, Fructus Jujubae 10, Auricularia 15, vitamin A 0.01, vitamin C 1.
3. medicine-food dual-purpose composition according to claim 1, it is characterized in that the weight of described raw material is as follows: RHIIZOMA DIOSCOREAE frOm Henan of China 20, the Radix Astragali 15, Radix Rehmanniae Preparata 15, Semen Coicis 10, Fructus Lycii 10, Fructus Crataegi 15, Bulbus Lilii 5, Semen Nelumbinis 5, Fructus Jujubae 5, Auricularia 10, vitamin A 0.02, vitamin C 2.
4. according to the arbitrary described medicine-food dual-purpose composition of claim 1-3, it is characterized in that it is that the sweeting agent of 1-3 is prepared into granule, oral liquid, supping or semi-fluid food that described medicine-food dual-purpose composition is added weight portion again.
5. the preparation method of the described medicine-food dual-purpose composition of claim 4 is characterized in that, comprises the steps:
1) get the Radix Astragali, Radix Rehmanniae Preparata, Semen Coicis, the Fructus Lycii of described weight portion, pulverize, mix, add 6-10 times of water gaging, heating extraction 45 minutes-1.5 hours is extracted 3 times, merge extractive liquid,, and filtration, filtrate decompression is concentrated into the clear paste that relative density is 1.25-1.4;
2) get RHIIZOMA DIOSCOREAE frOm Henan of China, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae, the Auricularia of described weight portion, pulverize, join in the above-mentioned clear paste with vitamin A, vitamin C, add sweeting agent again, mixing is granulated, and drying is sieved, and granule is made in packing.
6. the preparation method of the described medicine-food dual-purpose composition of claim 4 is characterized in that, comprises the steps:
1) gets RHIIZOMA DIOSCOREAE frOm Henan of China, the Radix Astragali, Radix Rehmanniae Preparata, Semen Coicis, Fructus Lycii, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae, the Auricularia of described weight portion, pulverize, mix, add 6-10 times of water gaging, heating extraction 45 minutes-1.5 hours is extracted merge extractive liquid, 3 times, filter, filtrate decompression is concentrated into the concentrated solution that relative density is 1.1-1.2, adds 60% ethanol of 2 times of amounts, leaves standstill, get supernatant liquid filtering, filtrate decompression is concentrated into the concentrated solution that relative density is 1.1-1.2;
2) add vitamin A, vitamin C, citric acid, sweeting agent, add water and be made into medicinal liquid, fill, oral liquid is made in sterilization.
7. the preparation method of the described medicine-food dual-purpose composition of claim 4 is characterized in that, comprises the steps:
1) get the Radix Astragali, the Radix Rehmanniae Preparata of described weight portion, pulverize separately adds 6-10 times of water gaging, and heating extraction 45 minutes-1.5 hours is extracted 3 times, and merge extractive liquid, filters, and obtains Radix Astragali extract and Radix Rehmanniae Preparata extract;
2) RHIIZOMA DIOSCOREAE frOm Henan of China, Semen Coicis, Fructus Lycii, Fructus Crataegi, Bulbus Lilii, Semen Nelumbinis, Fructus Jujubae of getting described weight portion cleaned and placed pot, adds 10 times of water gagings, soaks after 30 minutes, heat endure ripe;
3) add Radix Astragali extract and the Radix Rehmanniae Preparata extract that step 1) makes, and Auricularia, vitamin A, vitamin C, continue to be brewed into pasty state, add sweeting agent, cooling promptly gets nutrient porridge.
8. according to each described preparation method of claim 5-7, it is characterized in that described sweeting agent is Icing Sugar, xylitol, sucralose, stevioside, Mel, crystal sugar or its combination.
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| CN2009102661370A CN101711840B (en) | 2009-12-30 | 2009-12-30 | Medicine-food dual-purpose composition suitable for cancerous patients and preparation method thereof |
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| CN101711840A CN101711840A (en) | 2010-05-26 |
| CN101711840B true CN101711840B (en) | 2011-09-14 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101971978B (en) * | 2010-07-26 | 2012-05-30 | 山西振东五和健康食品股份有限公司 | Nutrient porridge based on malignant tumor radiotherapy patient |
| CN104605372A (en) * | 2015-02-10 | 2015-05-13 | 王中卫 | Nutritional herbal cuisine based on cancer radiotherapy patient and preparation method thereof |
| CN109288058A (en) * | 2018-12-05 | 2019-02-01 | 北京富乐喜科技有限公司 | A kind of active health-care preparation of fullerene enhancing normal cell and preparation method |
| CN112641896A (en) * | 2019-10-10 | 2021-04-13 | 王忠民 | Medicine for quickly enhancing immunity of human body and preventing tumor |
| CN112998257A (en) * | 2021-03-29 | 2021-06-22 | 戴清桂 | Dietetic therapy composition and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1274599A (en) * | 1999-05-20 | 2000-11-29 | 周金龙 | Cancer treating medicine and its preparation |
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| CN1274599A (en) * | 1999-05-20 | 2000-11-29 | 周金龙 | Cancer treating medicine and its preparation |
Non-Patent Citations (2)
| Title |
|---|
| 李晓勤，郭爱华.肿瘤与药膳食疗.《临床医药实践杂志》.2004,第13卷(第1期),第63-64页. * |
| 项平,施洪飞,唐善永.药膳配伍规律研究.《扬州大学烹饪学报》.2002,第19卷(第67期),第23-27页. * |
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