CN112930342B - 制备联氟砜的方法和中间体 - Google Patents
制备联氟砜的方法和中间体 Download PDFInfo
- Publication number
- CN112930342B CN112930342B CN201980069064.8A CN201980069064A CN112930342B CN 112930342 B CN112930342 B CN 112930342B CN 201980069064 A CN201980069064 A CN 201980069064A CN 112930342 B CN112930342 B CN 112930342B
- Authority
- CN
- China
- Prior art keywords
- formula
- cfx
- reaction
- organic solvent
- mercaptothiazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736498P | 2018-09-26 | 2018-09-26 | |
| US62/736,498 | 2018-09-26 | ||
| PCT/IL2019/051063 WO2020065652A1 (en) | 2018-09-26 | 2019-09-26 | Process and intermediates for the preparation of fluensulfone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112930342A CN112930342A (zh) | 2021-06-08 |
| CN112930342B true CN112930342B (zh) | 2024-10-11 |
Family
ID=68387378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980069064.8A Active CN112930342B (zh) | 2018-09-26 | 2019-09-26 | 制备联氟砜的方法和中间体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11634397B2 (https=) |
| JP (1) | JP7397070B2 (https=) |
| KR (1) | KR102608979B1 (https=) |
| CN (1) | CN112930342B (https=) |
| AR (1) | AR116506A1 (https=) |
| AU (1) | AU2019346158B2 (https=) |
| PY (1) | PY1980072A (https=) |
| WO (1) | WO2020065652A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114805240B (zh) * | 2022-06-28 | 2022-09-16 | 湖南速博生物技术有限公司 | 一种一锅法合成氟烯线砜的方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998047884A1 (en) * | 1997-04-24 | 1998-10-29 | Zeneca Limited | Process for the production of 5-chloro-2- (4,4-difluorobut-3-enylsulphonyl) thiazole and intermediates therefor |
| WO2003095401A1 (de) * | 2002-05-13 | 2003-11-20 | Bayer Cropscience Aktiengesellschaft | Verfahren zur herstellung von substituierten trifluorethylenen |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2603647A (en) | 1951-10-18 | 1952-07-15 | Goodrich Co B F | Preparation of 2-mercapto thiazoles |
| US2603648A (en) | 1951-10-18 | 1952-07-15 | Goodrich Co B F | Preparation of 2-mercapto thiazoles |
| EP0228447A4 (en) | 1985-06-20 | 1990-12-27 | Fmc Corporation | Pesticidal polyhaloalkene derivatives |
| IL112721A0 (en) * | 1994-03-10 | 1995-05-26 | Zeneca Ltd | Azole derivatives |
| JP3899626B2 (ja) | 1997-12-26 | 2007-03-28 | 宇部興産株式会社 | ２−メルカプトチアゾ−ルの製法 |
| JP2001019685A (ja) | 1999-07-06 | 2001-01-23 | Nippon Bayer Agrochem Co Ltd | 殺センチュウ性トリフルオロブテン類 |
| JP2003113168A (ja) | 2001-09-28 | 2003-04-18 | Bayer Ag | 殺センチュウ性トリフルオロブテン誘導体 |
| DE10221119A1 (de) | 2002-05-13 | 2003-12-04 | Bayer Cropscience Ag | Verfahren zur Herstellung von substituierten Trifluorethylenen |
| DE10229776A1 (de) | 2002-07-03 | 2004-01-22 | Bayer Cropscience Ag | Verfahren zum Herstellen von heterocyclischen Fluoralkenylsulfonen |
| CN111670180A (zh) * | 2017-12-20 | 2020-09-15 | Pi工业有限公司 | 氟烯基化合物，制备方法及其用途 |
-
2019
- 2019-09-25 PY PY201901980072A patent/PY1980072A/es unknown
- 2019-09-25 AR ARP190102726A patent/AR116506A1/es unknown
- 2019-09-26 KR KR1020217011965A patent/KR102608979B1/ko active Active
- 2019-09-26 CN CN201980069064.8A patent/CN112930342B/zh active Active
- 2019-09-26 US US17/280,146 patent/US11634397B2/en active Active
- 2019-09-26 JP JP2021517567A patent/JP7397070B2/ja active Active
- 2019-09-26 WO PCT/IL2019/051063 patent/WO2020065652A1/en not_active Ceased
- 2019-09-26 AU AU2019346158A patent/AU2019346158B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998047884A1 (en) * | 1997-04-24 | 1998-10-29 | Zeneca Limited | Process for the production of 5-chloro-2- (4,4-difluorobut-3-enylsulphonyl) thiazole and intermediates therefor |
| WO2003095401A1 (de) * | 2002-05-13 | 2003-11-20 | Bayer Cropscience Aktiengesellschaft | Verfahren zur herstellung von substituierten trifluorethylenen |
Non-Patent Citations (1)
| Title |
|---|
| Fluoroalkane thioheterocyclic derivatives and their antitumor activity;Guangxiao Li等;《European Journal of Medicinal Chemistry》;第93卷;423-430页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022503882A (ja) | 2022-01-12 |
| US11634397B2 (en) | 2023-04-25 |
| US20220002258A1 (en) | 2022-01-06 |
| JP7397070B2 (ja) | 2023-12-12 |
| CN112930342A (zh) | 2021-06-08 |
| AR116506A1 (es) | 2021-05-12 |
| AU2019346158A1 (en) | 2021-05-06 |
| PY1980072A (es) | 2020-06-05 |
| BR112021005745A2 (pt) | 2021-07-27 |
| WO2020065652A1 (en) | 2020-04-02 |
| KR102608979B1 (ko) | 2023-11-30 |
| KR20210072010A (ko) | 2021-06-16 |
| AU2019346158B2 (en) | 2025-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |