CN112914656A - 具有高度柔性填充材料的囊内翻转编织物 - Google Patents

具有高度柔性填充材料的囊内翻转编织物 Download PDF

Info

Publication number
CN112914656A
CN112914656A CN202011401173.6A CN202011401173A CN112914656A CN 112914656 A CN112914656 A CN 112914656A CN 202011401173 A CN202011401173 A CN 202011401173A CN 112914656 A CN112914656 A CN 112914656A
Authority
CN
China
Prior art keywords
braid
shape
aneurysm
implant
tubular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202011401173.6A
Other languages
English (en)
Inventor
L·戈罗克豪
J·洛伦佐
R·徐
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Synthes Products Inc
Original Assignee
DePuy Synthes Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DePuy Synthes Products Inc filed Critical DePuy Synthes Products Inc
Publication of CN112914656A publication Critical patent/CN112914656A/zh
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027—Type of occlusion
    • A61B17/12031—Type of occlusion complete occlusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04C—BRAIDING OR MANUFACTURE OF LACE, INCLUDING BOBBIN-NET OR CARBONISED LACE; BRAIDING MACHINES; BRAID; LACE
    • D04C1/00—Braid or lace, e.g. pillow-lace; Processes for the manufacture thereof
    • D04C1/06—Braid or lace serving particular purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00862—Material properties elastic or resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Textile Engineering (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

本发明题为“具有高度柔性填充材料的囊内翻转编织物”。本发明提供了一种管状编织植入物，该管状编织植入物包括编织物，该编织物可作为单层编织物递送，在部署期间向内翻转以形成至少两个嵌套的囊，并且包括可填充最内层囊的附加编织材料。该附加编织物材料可像带状物一样成环或盘绕和/或翻转以形成越来越小的嵌套囊。该编织物可沿其长度具有可变的编织角，使得当被定位以用于递送时，该编织物可在其远侧端部附近具有高编织角并且在近侧端部附近具有低编织角。除此之外或作为填充最内层囊的编织物材料的替代物，该植入物可包括可在最内层囊内成环的栓塞性线圈。

Description

具有高度柔性填充材料的囊内翻转编织物
技术领域
本发明整体涉及医疗器械，并且更具体地涉及用于动脉瘤治疗的栓塞性植入物。
背景技术
颅内动脉瘤可为复杂的并且可因其靠近关键脑组织而难以治疗。现有解决方案包括血管内治疗，其中动脉瘤囊的内部体积被移除或排除在动脉血压和血流之外。血管内或其它外科手术方法的当前另选方案可包括在血管内递送的治疗装置，该治疗装置利用栓塞性材料填充动脉瘤的囊或者阻塞动脉瘤的入口或颈部。这两种方式均试图阻止血液流入动脉瘤内。当填充动脉瘤囊时，栓塞性材料使血液凝块，从而在动脉瘤内产生血栓块。当治疗动脉瘤颈部时，进入动脉瘤入口的血流被禁止，从而诱导动脉瘤中的静脉停滞并促进动脉瘤内的血栓块的自然形成。
当前的血管内递送装置通常利用多个栓塞性线圈来填充囊或治疗动脉瘤的入口。与利用栓塞性线圈填充的动脉瘤块相比，通过利用栓塞性线圈治疗入口而形成的自然形成的血栓块可导致改善愈合，因为自然形成的血栓块可降低从动脉壁的扩张的可能性并且有助于沿着颈部平面重新结合到原始载瘤血管形状中。然而，递送到动脉瘤颈部的栓塞性线圈可能具有阻碍相邻血管中的血液流动的不利影响，特别是在入口处过度填充的情况下。相反，如果入口未被充分填充，则血流可以持续进入动脉瘤中。治疗某些动脉瘤形态(例如，宽颈部、分叉等)可需要辅助装置(诸如支架或球囊)来支撑线圈质量并获得期望的堆积密度。一旦植入，线圈就不容易回缩或重新定位。此外，栓塞性线圈并不能总是有效地治疗动脉瘤，因为利用多个线圈治疗的动脉瘤通常因卷曲不良、缺乏横跨动脉瘤颈部的覆盖、血流或较大的动脉瘤尺寸而再通或压缩。
正在探索栓塞性线圈的替代方案，例如管状编织植入物公开于美国专利公布号2018/0242979中，该专利公布以引用方式并入本文。管状编织植入物有可能轻松、准确且安全地治疗载瘤血管中的动脉瘤或其它动静脉畸形，同时不会阻塞流入与载瘤血管连通的穿支血管的血流。然而，与栓塞性线圈相比，管状编织植入物是较新的技术，因此对于管状编织植入物，具有改善几何形状、构型、递送系统等的能力。
因此，需要针对用于动脉瘤治疗的植入物的改善的方法、装置和系统。
发明内容
本发明的目的是提供满足上述需求的系统、装置和方法。总体上，本发明的目的是提供管状编织植入物，该管状编织植入物包括可作为单层编织物递送的编织物，该编织物可在部署期间向内翻转以形成至少两个嵌套的囊，并且可包括可填充最内层囊的附加编织材料。该附加编织物材料可像带状物一样成环或盘绕和/或翻转以形成越来越小的嵌套囊。为了获得可翻转和填充动脉瘤的植入物，可将编织物制造成使得编织物在远侧端部被制作得更强，从而在被植入时倾向于朝预定形状移动并形成两个嵌套囊，并且在近侧端部处，编织物可制作得更弱，从而倾向于在囊内变平和折叠成条带形状。编织物可沿其长度具有可变的编织角，使得当被定位以用于递送时，编织物可在其远侧端部附近具有高编织角并且在近侧端部附近具有低编织角。除了可变编织角之外，或作为另一种选择，可对编织物进行热处理以使编织物在近侧端部处弱化。除此之外或作为填充最内层囊的编织物材料的替代物，该植入物可包括可在最内层囊内成环的栓塞性线圈。
用于治疗动脉瘤的示例性方法可包括以非特定顺序呈现的以下步骤中的一个或多个步骤。该示例性方法还可包括此处未列出的附加步骤。可选择具有第一端部、第二端部、从第一端部延伸的第一部分和从第二端部延伸的第二部分的基本上管状的编织物。可选择基本上管状的编织物，使得当编织物为沿从编织物的一端到编织物的另一端的长度具有均匀圆周的单层圆柱形形状时，与编织物的第一部分相比，编织物在编织物的第二部分中具有较小的编织角。编织物可被选择成使得当编织物为单层圆柱形形状时，其具有从第一部分延伸到第二部分的连续减小的编织角。
编织物可通过微导管被递送到动脉瘤。编织物可以单层管状形状递送，使得第一端部相对于第二端部定位在远侧方向上。
编织物的第一部分可膨胀到动脉瘤的壁。近侧翻转部可在动脉瘤的颈部处形成在编织物中。编织物的翻转的部分可膨胀以压到膨胀的第一部分中。远侧翻转部可在动脉瘤的壁的远侧部分处形成在编织物中，使得编织物的翻转的部分在远侧翻转部和近侧翻转部之间延伸。
可将编织物成形为在翻转的部分内形成在动脉瘤的壁的远侧部分附近的圆顶。除此之外或另选地，编织物可在远侧翻转部处扭曲，并且编织物可膨胀以在翻转的部分内形成囊。
编织物的第二部分可定位在翻转的部分内，以与翻转的部分直接接触、定位在形成于翻转的部分内的囊内或以其他方式定位在翻转的部分内。编织物的第二部分可被定位成使得第二部分在翻转的部分内变平并成环。
可选择栓塞性线圈。栓塞性线圈可被定位成使得其附连到编织物的第二端部。栓塞性线圈可通过微导管被递送到动脉瘤。栓塞性线圈可位于植入编织物的翻转的部分内。
示例性植入物可包括具有两个端部的管状编织物，该管状编织物能够成形为单层圆柱形形状，该单层圆柱形形状具有可从一端到另一端测量的长度，沿该长度的基本上均匀的圆周，在编织物的从两个端部中的第一端部延伸的第一部分上具有较大编织角，并且在编织物的从两个端部中的第二端部延伸的第二部分上具有较小编织角。在单层圆柱形形状中，编织物可具有从第一部分延伸到第二部分的连续减小的编织角。在单层管状形状中，编织物的尺寸可被设定成使其通过微导管被递送到动脉瘤。
编织物可从单层圆柱形形状移动成植入形状。在植入形状中，第一部分可被定位成与动脉瘤壁并置，翻转部囊可被定位成将第一部分压到动脉瘤壁，并且第二部分可被定位在翻转部囊内。在植入形状中，编织物的第二部分的至少一部分可在翻转的部分内成环。在植入形状中，第二部分可被定位成将翻转的部分压到第一部分。
在植入形状中，内囊可被定位成将翻转部囊压到第一部分，编织物可具有将内囊和翻转部囊分开的翻转部，并且编织物可在该翻转部处扭曲。
在植入形状中，编织物可在定位于动脉瘤的壁的远侧部分附近的翻转部囊内具有圆顶形状。
植入物还可包括附连到编织物的第二端部的栓塞性线圈。在植入形状中，编织物可被成形为允许栓塞性线圈定位在翻转部囊内，以与翻转部囊直接接触、通过编织材料与翻转部囊分开或者以其他方式定位在翻转部囊内。
另一种示例性植入物可包括具有第一端部和第二端部的管状编织物。该编织物可具有预定形状，该预定形状具有两个翻转部，它们将编织物分成三个节段：从第一端部延伸到两个翻转部中的第一翻转部的外部节段；在两个翻转部之间延伸并且至少部分地被外部节段围绕的中间节段；以及从两个翻转部中的第二翻转部延伸到第二端部且至少部分地被中间节段围绕的内部节段。在预定形状中，编织物可在内部节段上的位置处具有编织角的陡变，使得从第二翻转部延伸的内部节段的远侧部分具有比从第二端部延伸的内部节段的近侧部分更高的编织角。
编织物可移动形成尺寸被设定成使其定位在动脉瘤囊内的预定形状。在植入形状中，编织物的对应于在预定形状中的内部节段的部分可塌缩成条带形状并且定位在由编织物的对应于在预定形状中的中间节段的部分形成的翻转部囊中。
编织物可被成形为单层圆柱形形状，该单层圆柱形形状在编织物的两个端部之间具有基本上均匀的圆周，在编织物的从第一端部延伸的第一部分中具有较大的编织角，并且在编织物的从第二端部延伸的第二部分中具有较小的编织角。在单层圆柱形形状中，编织物可具有从第一部分到第二部分的连续减小的编织角。在单层圆柱形形状中，编织物的尺寸可被设定成使其通过微导管被递送到动脉瘤。
附图说明
将参考下面的描述并结合附图进一步讨论本发明的上述及其他方面，在这些附图中，类似的编号指示各种图中类似的结构元件和特征结构。附图未必按比例绘制，相反，将重点放在示出本发明的原理。附图仅以举例方式而非限制方式描绘了本发明装置的一种或多种具体实施。
图1是根据本发明的各方面的具有成形用于通过导管递送的编织物的植入物的图示；
图2是根据本发明的各方面的具有处于预定形状的编织物的植入物的图示；
图3A至图3I是根据本发明的各方面的动脉瘤治疗过程的步骤的图示；
图4示出了根据本发明的各方面的具有在远侧翻转部处扭曲的编织物的植入物；
图5A至图5B是根据本发明的各方面的动脉瘤治疗过程的步骤的图示；
图6是根据本发明的各方面的具有各自成形用于通过导管递送的编织物和栓塞性线圈的植入物的图示；
图7是根据本发明的各方面的具有编织物和栓塞性线圈并且编织物处于预定形状的植入物的图示；
图8是根据本发明的各方面的植入在动脉瘤中的具有编织物和栓塞性线圈的植入物的图示；并且
图9是列出可根据本发明的各方面执行的方法步骤的流程图。
具体实施方式
在宽颈动脉瘤的已知治疗中，通常通过将栓塞性线圈放置在动脉瘤囊内并且跨动脉瘤颈部将支架放置在亲代血管内来治疗动脉瘤。在许多情况下，支架是必要的，以抑制栓塞性线圈进入亲代血管。如果栓塞性线圈进入亲代血管，则线圈可阻塞血管并且/或者凝块可在血管内的线圈上形成并在亲代血管中产生栓塞。编织动脉瘤囊内植入物可用于治疗宽颈动脉瘤，而不需要支架将编织植入物固定在动脉瘤颈部处。然而，为了实现将编织植入物锚定在宽颈分叉中所必需的力，编织物可以是刚性的并且能够抵抗再成形为与预定形状显著不同的植入形状。因此，在一些情况下，可能具有挑战性的是以足够的编织密度填充动脉瘤以快速且有效地诱导动脉瘤囊内的血液停滞。被制造得太软的编织物的形状会变紧凑，并且当植入物不再密封动脉瘤的颈部时，导致动脉瘤再通。
本发明的各方面涉及解决上述挑战。在本文提供的示例中，管状编织植入物可包括如下编织物，该编织物可作为单层编织物递送，可在部署期间向内翻转以形成至少两个嵌套的囊，并且可包括可填充最内层囊的附加编织材料。该附加编织物材料可像带状物一样成环或盘绕和/或翻转以形成越来越小的嵌套囊。本发明的一个方面是提供如下结构，该结构允许将足够量的附加编织材料放置到最内层囊中，使得动脉瘤快速凝结以用于有效治疗。
当在本文中使用时，术语“管状”和“管”应广义地理解，并且不限于为正圆柱体的或横截面为完全圆周的或在其整个长度上具有均匀横截面的结构。为简单起见，本文通常将管状结构示出为具有基本上正圆柱形结构。然而，在不脱离本发明范围的情况下，管状结构可具有锥形或弯曲外表面。
为了满足对用于实现在动脉瘤内的牢固锚定的编织物刚度和用于使编织物在动脉瘤内变形为高填充密度的编织物柔软度的竞争需求，编织物可被制成使得当动脉瘤具有较高填充密度时编织物的被推入动脉瘤中的部分与编织物的膨胀以将编织物锚定在动脉瘤内的较硬部分相比较弱。编织物部分的刚度/柔性可通过编织角(例如，每英寸纬数)、股线直径、股线数量、股线材料和/或用于改变股线材料特性的处理(例如，热处理)等来控制。与较弱部分相比，较硬部分可具有较高的编织角、较大的股线直径、较多的股线、包含较硬材料的股线和/或被处理成具有较大刚度的股线。
当通过导管递送编织物时，编织物的较硬部分可定位在编织物的远侧端部附近，使得编织物的较硬部分在动脉瘤被填充之前离开导管并且膨胀以锚定在动脉瘤中。编织物的较硬部分可通过热定形或其他方式成形为预定形状，使得当较硬部分时，它们膨胀成预定形状。使编织物的较硬部分膨胀成预定形状的倾向可抵靠动脉瘤壁产生足够的力以将编织物锚定在动脉瘤囊中。当通过导管递送编织物时，编织物的较弱部分可定位在编织物的近侧端部附近。编织物的具有最大柔性的部分可动态地变形以在动脉瘤内成环或嵌套，从而在编织物的更硬的锚定部分内折叠。
除此之外或作为填充最内层囊的编织物材料的替代物，该植入物可包括可在最内层囊内成环的栓塞性线圈。
本文所述的示例通常包括编织植入物，该编织植入物可以固定在动脉瘤囊内并且堵塞大部分动脉瘤颈部。该植入物可包括具有较硬部分和较弱部分的管状编织物，至少该较硬部分被设定为预定形状，该编织物能够压缩以用于通过微导管递送，并且编织物能够植入到基于其中植入编织物的动脉瘤的几何形状并且至少部分地基于预定形状的植入位置中。
如图1所示，示例性植入物100可包括编织物110，该编织物可被成形为基本上管状的单层形状，该单层形状具有在每个端部112、114之间测量的长度L和沿长度L的可变刚度。如图所示，刚度可至少部分地由编织角θ1、θ2、θ3、θ4确定。为了便于讨论，编织物的较弱、较柔韧的部分被示出为与编织物的较强、较硬的部分相比具有较低的编织角；然而，编织物的较弱部分和较硬部分可在股线直径、股线数量、股线材料方面有所不同，其可被处理成具有不同的刚度/柔性，和/或通过本领域的普通技术人员将会知道和理解的其他方式产生不同。此外，包括具有不同刚度的编织物节段的示例性植入物可包括被接合以形成编织物的两个分开的区段，并且编织物不需要包括具有不同刚度的节段作为连续的编织管。
在图1所示的单层管状形状中，编织物110可具有沿长度L的基本上均匀的圆周C。该管状形状可具有沿编织物110的长度延伸的中心轴线A。如图所示并且如本领域的普通技术人员根据本文的教导内容原本将理解的，编织角θ1、θ2、θ3、θ4可通过将编织股线的切向轨线与中心轴线A进行比较来测量。
编织物可包括多根股线，例如约4至约96根股线，每根股线从一个编织物端部112延伸到另一个编织物端部114。如本文所用，针对任何数值或范围的术语“约”或“大约”指示允许部件或元件的集合实现如本文所述的其预期要达到的目的的合适的尺寸公差。更具体地，“约”或“大约”可指列举值的值±20％的范围，例如“约90％”可指71％至99％的值范围。股线可围绕圆周C螺旋缠绕。股线的数量、股线的角度、股线的直径、股线的材料和股线的材料特性均可为控制编织物110的材料特性(包括孔隙率和柔性)的因素。编织股线可被织造成使得约一半股线以顺时针螺旋缠绕，另一半以逆时针螺旋缠绕，并且相反缠绕的股线交替地彼此交叉和相互重叠。由于这样的构造，与编织物的具有较低编织角的部分相比，编织物的具有较高编织角的部分可具有较高的股线密度。较高的股线密度可产生较致密、较硬的编织物部分。
股线可由多种合金诸如镍钛合金、钴铬合金、铂、镍钛诺、不锈钢、钽或其他合金或者任何其他合适的生物相容材料或这些材料的组合制成。而且，这些材料可随着时间的推移被患者吸收或不可被患者吸收。编织物110中的一些或全部可为复丝圆柱形网，该网优选由用于获得射线不透性的具有交织铂丝的镍钛诺或者具有约10％至40％铂的拉伸填充管(DFT)镍钛诺制成。编织物110的网中的开孔也可形成基本一体的框架或网。因此，开孔可具有可变的尺寸、形状或孔隙度，并且可在整个编织物110的网壁内均匀或随机地间隔开。开孔可提供具有柔性的编织物110，并且还有助于编织物从塌缩状态转变为膨胀的部署状态，反之亦然。
如图1所示的编织物110描绘了如从编织物110的近侧端部112到远侧端部114所测量的增加的四个编织角θ1、θ2、θ3、θ4，其中编织物110的近侧部分116中的编织角θ4最小，紧邻近侧部分116远侧的区段中的编织角θ3大于近侧部分116中的编织角θ4，下一个远侧区段中的编织角θ2大于紧邻其近侧的区段中的编织角θ3，并且编织物110的最远侧区段118中的编织角θ1最大。应当知道和理解，编织物110可包括具有不同编织角，从而具有不同刚度/柔性的两个或更多个区段。编织物可另外包括编织角的连续梯度变化，从而具有从一个编织物区段到另一个编织物区段的刚度/柔性的连续梯度变化，例如编织角可从近侧部分116到远侧部分118连续变化。
当编织物110的尺寸被设定成使其横贯导管时，植入物100可被递送到动脉瘤中。例如，编织物110可以如图1所示的单层管状形状递送，使得编织物的一端114是被定位成在编织物110的其余部分之前离开导管的远侧端部，并且另一端112是被定位成在编织物110的其余部分之后离开导管的近侧端部。另选地，编织物可以包括折叠部、翻转部和/或多层的其他形状递送。无论递送形状如何，编织物110都可具有被定位成在编织物110的其余部分之前离开导管的远侧部分118和被定位成在编织物110的其余部分之后离开导管的近侧部分116。远侧部分118可具有高编织角θ1，使得远侧部分118具有足够的刚度以将编织物110锚定在动脉瘤内。近侧部分116可具有低编织角θ4，使得近侧部分具有足够的柔性以塌缩到包含编织物110的其余部分的动脉瘤囊中。植入物100还可包括被配置成可拆卸地附接到植入物递送系统的脱离特征部150。脱离特征部150可在编织物110的近侧端部112处附连到编织物110。
图2示出了成形为预定形状的编织物110，诸如图1所示的编织物110。编织物110可包括记忆形状材料，诸如镍钛诺、镍钛诺合金、聚合物记忆形状材料或具有如本文所述的用于再成形的特性的其他记忆形状材料。编织物110可通过热定形或本领域普通技术人员知道和理解的其他方式设定为预定形状。编织段110可从预定形状塌缩成变形形状，该变形形状的尺寸被设定成使其横贯微导管到达动脉瘤。在离开微导管并与血液接触时，编织物110可从变形形状朝预定形状移动。动脉瘤和治疗部位的解剖结构可抑制编织物110移动成预定形状，使得当编织物110被部署时，其可呈现部分地基于预定形状和其中植入编织物的解剖结构的形状的部署形状。
在预定形状中，编织物110可包括两个翻转部122、124和将编织物110分成四个节段142、144、146、130的捏夹点126。在预定形状中，编织物110可具有从编织物110的开口端114延伸到两个翻转部122、124的第一翻转部122的外部节段142；在两个翻转部122和124之间延伸的中间节段144；从两个翻转部122、124的第二翻转部124延伸到编织物110的捏夹点126的内部节段146；以及从捏夹点126延伸到编织物110的相对端112的细长区段130。当处于预定形状时，管状编织物110可围绕中心竖直轴线y基本上径向对称。
图2示出了每个节段142、144、146、130的轮廓。脱离特征部150被示出为可与机械植入物递送系统(未示出)一起使用的扁平键。在例如美国专利申请公布号2019/0192162和2019/0328398中描述了示例性植入物递送系统，每个专利申请公布以引用方式全文并入本文。在植入物的递送和/或定位期间，键150可通过射线照相方法可视化。键150可从递送系统释放，从而将植入物100从递送系统释放。当释放植入物时，键可保持附接到植入物。
管状编织物110可以通过以下方式成形为预定形状：首先在捏夹点126处捏夹编织物110；然后将编织物向外翻转以利用翻转部124将内部节段146与中间节段144分离；然后，使中间节段144在形状结构件(form)上成形以产生所示的基本上“S”形的轮廓；并且最后将编织物110再次向外翻转以利用另一个翻转部122将中间节段144与外部节段142分离。任选地，编织物可在开口端114和/或近侧端部112处被修剪。开口端部114可以被定位成环绕中间节段144。开口端部114可以定位在编织物高度的中间第三节段内，如图所示。另选地，开口端114可定位在别处，例如在远侧翻转部124的附近。
外囊142可对应于如图1所示的编织物110的远侧部分118。当为图1所示的单层管状形状时，远侧部分118可沿其长度具有基本上均匀的编织角θ1。编织物110可在近侧拐折122处具有编织角的陡变。编织物110可具有穿过中间区段144和内部区段146的渐变的编织角变化。尾部130可具有沿尾部130的长度的基本上一致的编织角θ4。尾部130可对应于如图1所示的呈单层管状形状的编织物110的近侧部分116。
另选地，当编织物110呈单层管状形状时，在捏夹点126远侧的区段142、144、146可具有沿这些区段142、144、146的长度一致的高编织角θ1；尾部区段130可具有沿其长度一致的低编织角θ4，并且编织物110可在捏夹点126处具有编织角的陡变。尾部130可具有足够的柔性，使得当在血管内治疗部位处被操纵时，尾部130变平成条带形状并自身折叠。另选地，编织物110可在近侧拐折122处、在远侧拐折124处、在捏夹点126处或在它们的任何组合处包括编织角的陡变。
编织物110在开口端114处的股线可为自由的切割端；或者另选地，开口端114处的股线可为闭合的，这意味着开口端114处的编织物内的股线通过胶接、焊接等方式彼此附接，或者股线在开口端114处弯折。自由的切割端可具有更容易制造的优点，而闭合的股线端可具有比切割端更好地防止损伤的优点。
图3A至图3I示出了经由导管20植入动脉瘤10中的植入物100，诸如图1和/或2中所示的植入物100。导管20的尺寸可在考虑导管所必须穿过以到达治疗部位的动脉瘤或体腔的尺寸、形状和方向性的情况下加以选择。导管20可具有约80厘米至约170厘米的总可用长度。导管20可具有约0.015英寸至0.032英寸的内径ID。外径OD的尺寸也可变化并且可在其近侧端部或远侧端部处变窄。导管20在其近侧端部26处可由最终使用者手动操作，并且在其远侧端部处可操作(如图所示)以定位在动脉瘤10的颈部16处。虽然导管20的远侧端部可包含植入物100，但远侧端部的形状可变化并且可以弯曲成角度。
图3A示出了编织物110的开口端114在动脉瘤10的囊12内膨胀以接触动脉瘤10的壁14。接触动脉瘤壁14的区段142'可对应于图2中所示的在预定形状中的外部区段142和/或图1中所示的编织物110的远侧较硬区段118。植入物100可被选择用于治疗，使得所选择的植入物100具有在预定形状中的外部节段142，该外部节段142的周长大于动脉瘤囊12的周长，这意味着编织物110的与动脉瘤壁14接触的区段142'在其趋于膨胀成预定形状时提供抵靠动脉瘤壁的力。因此，外部区段142'的植入形状的周长可小于外部区段142的预定形状。
图3B示出了翻转形成呈植入形状的近侧翻转部122'的编织物110。近侧翻转部122'可对应于在预定形状中的近侧翻转部122。
图3C示出了在外部区段142'内膨胀的编织物110。
图3D示出了在外部区段142'内部形成内囊144'的编织物。远侧翻转部124'被示出定位在动脉瘤壁14的远侧部分15的附近。远侧翻转部124'可对应于编织物110的在预定形状中的远侧翻转部124。内囊144'可对应于图2中所示的在预定形状中的中间节段144。内囊144'可对应于图1中所示的编织物110的刚性远侧部分118和/或编织物110的刚度小于远侧部分118的一部分。内囊144'可对应于编织物110的刚度大于图1所示的柔性近侧部分116的一部分。
图3E示出了进一步离开导管20并在内囊114'内膨胀的编织物110的可塌缩部分146'。可塌缩部分146'可对应于编织物110的在预定形状中的内部节段146。可塌缩部分146'可对应于图1中所示的编织物110的刚性远侧部分118和/或编织物110的刚度小于该远侧部分的一部分。可塌缩部分146'可对应于编织物110的刚度大于图1所示的柔性近侧部分116的一部分。
图3F示出了在远侧翻转部124'附近形成圆顶的可塌缩部分146'。在由可塌缩部分146'形成的圆顶的近侧上示出了捏夹点126'。在植入形状中的捏夹点126'可对应于在预定形状中的捏夹点126。
图3G示出了编织物110的近侧尾部130'变平成条带形状并且在由内囊144'和可塌缩部分146'的圆顶限定的空间内折叠。近侧尾部130'可对应于如图2所示的编织物的在预定形状中的近侧尾部130。近侧尾部130'可对应于图1中所示的柔性近侧部分116。
图3H示出了在由内囊144'和可塌缩部分146'的圆顶限定的空间内折叠的近侧尾部130'的附加长度。
图3I示出了呈最终植入形状的植入物100。外部区段142'、内囊144'和可塌缩部分146'以横截面示出，以更好地示出近侧尾部130'的折叠条带形状。
图4示出了编织物110的另选植入形状。如图4所示，编织物110可包括靠近远侧翻转部124'的扭曲125。在具有如图4所示的扭曲125或如图3I所示不具有扭曲的情况下，内囊144'可提供压到动脉瘤壁14和/或外部区段142'中的力F1，这取决于外部区段142'的覆盖范围。还示出了外部区段142'的另选构型，该构型使得开口端114定位为靠近动脉瘤壁14的远侧部分15。
图5A和图5B示出了图4中所示的植入物100的后续植入步骤。图5A示出了在前述第一内囊142'内膨胀的第二内囊132。图5B示出了提供压向第一内囊142'的第二力F2的第二内囊132。编织物110在图5B中以横截面示出。在后续植入步骤中，编织物110可形成附加的嵌套囊。除此之外或另选地，编织物可塌缩以形成条带形状并且折叠到由一个或多个嵌套囊限定的空间内，类似于如图3G至图3I所示。
图6示出了另选的植入物100a，其包括具有不同编织角θ1、θ4的两个区段116、118的编织物110；栓塞性线圈160和脱离键150。栓塞性线圈160可附接到编织物110的近侧端部112。编织物110的靠近近侧端部112的近侧部分116可具有小编织角θ4。编织物110的靠近编织物远侧端部114的远侧部分118可具有较大的编织角θ4。编织物110可被成形为如图6所示的单层管状形状。编织物可如本文别处所述被成形以用于递送。
图7示出了替代植入物100a，诸如图6所示的具有预定形状的编织物110的植入物100a。预定形状可类似于如关于图2所述具有四个区段142、144、146、130、两个翻转部122、124和捏夹点126。栓塞性线圈160可从编织物100的尾部区段130延伸。当被植入时，栓塞性线圈160可代替图3I所示的植入物100的尾部部分130'中的一些或全部。
图8示出了呈植入形状的植入物100a，诸如图6和/或图7中所示的植入物100a。编织物110在被植入时可具有类似于关于图3I和/或图4所公开的外部区段142'和内囊144'。栓塞性线圈160可在内囊144'内缠绕。
图9是概述用于使用植入物和/或系统治疗动脉瘤的示例性方法步骤的流程图，该植入物和/或系统是诸如本文所述的示例性植入物100、100a和/或系统、其变型或如本领域普通技术人员将了解和理解的另选的植入物和/或系统。
参见图9中概述的方法300，在步骤302中，可选择具有较强区段和较弱区段的管状编织物。所选择的管状编织物可包括本文所述的示例性管状编织物110、其变型或如本领域普通技术人员将了解和理解的其替代物。较强区段相对于较弱区段可具有较大的编织角，使得各编织物区段的强度分别至少部分地由相应的编织角确定。除此之外或另选地，可处理(例如，热处理)较强区段和较弱区段中的一者或两者以改变该一个或两个区段的材料特性，使得两个区段之间的强度差异至少部分地由处理来确定。除此之外或另选地，较强区段可具有比较弱区段数量更多的股线，使得各编织物区段的强度分别至少部分地由股线的数量确定。除此之外或另选地，与较弱区段中的股线的直径相比，较强区段中的股线可具有较大的直径，使得各编织物区段的强度分别至少部分地由股线的直径确定。除此之外或另选地，较强区段和较弱区段中的股线可包括不同的材料，使得各区段的强度分别至少部分地由股线的材料特性确定。
在步骤304中，可通过微导管将编织物递送到动脉瘤。编织物能够可拆卸地附接到细长的递送系统。植入物(以及由此编织物)可在递送系统的远侧端部处附接到递送系统。可将递送系统和植入物定位在微导管内，使得递送系统从微导管的近侧端部延伸。使用者(例如，医师)可通过操纵递送系统的从微导管的近侧端部延伸出来的部分来通过微导管递送植入物。使用者可类似于如图3A至图3I、图4、图5A至图5B和/或图8所示，如本文另外所描述，或者如本领域普通技术人员根据本文的教导内容所理解通过操纵递送系统从微导管的近侧端部延伸的部分来放置植入物。
在步骤306中，编织物的远侧端部可定位在动脉瘤壁14的远侧部分15处。编织物的远侧端部可被定位成如图4、图5A至图5B和/或图8所示。另选地，编织物的远侧端部可定位在别处，例如在动脉瘤壁14的中间三分之一内，如图3A至图3I所示在壁14的远侧部分15和动脉瘤颈部16之间的约一半位置处。
在步骤308中，编织物的较强区段可膨胀以形成与动脉瘤壁14的外囊并置。外囊的形状可类似于图4、图5A至图5B和/或图8所示的外囊142'。另选地，编织物的较强区段可膨胀以形成类似于图3A至图3I中所示的外部区段142'形状的碗状。
在步骤310中，近侧翻转部可在动脉瘤颈部处形成在编织物中。近侧翻转部的定位可类似于图3A至图3I、图4、图5A至图5B和/或图8所示的近侧翻转部122'。近侧翻转部的形状可类似于图3A至图3I、图4、图5A至图5B和/或图8所示的近侧翻转部122'。近侧翻转部122'可限定在步骤308中膨胀的外囊或外部区段与位于该外囊或外部区段内的翻转的部分之间的边界。
在步骤312中，翻转的部分可膨胀以形成位于外囊或外部区段内的囊。翻转的部分可压靠外囊(或外部区段)，从而将外囊(或外部区段)压到动脉瘤壁14中。翻转的部分可形成诸如图3A至图3I、图4、图5A至图5B和/或图8中所示内囊144'。
在步骤314中，可在编织物中形成远侧翻转部。远侧翻转部可限定在步骤312中膨胀的翻转部内囊的远侧。远侧翻转部可限定内囊与编织物的内部非翻转的部分之间的边界。编织物的内部非翻转的部分可包括编织物的较弱区段。
在步骤316中，编织物的较弱区段可定位在翻转部囊中。该较弱区段可变平成条带形状并折叠成翻转部囊中。较弱区段可如图3G至图3I所示，如本文另外所描述，并且/或者如本领域普通技术人员根据本文的教导内容所理解的那样变平和折叠。较弱区段可对应于编织物110的尾部区段130、130'。
本文所包含的描述是本发明的实施方案的示例，并且不旨在以任何方式限制本发明的范围。本发明设想了植入物的许多变型形式和修改形式，包括：另选的递送方法、另选的编织材料、用于实现编织材料的期望刚度/柔性的另选方式、附连到植入物的附加结构(例如，有助于锚定植入物、血流转向、栓塞形成等的附加结构)、另选的预定编织物形状(例如，一个翻转部、三个翻转部、四个翻转部、五个或更多个翻转部、非径向对称形状、另选的节段形状等)、另选的植入形状等。对于接受本公开的教导内容的本领域普通技术人员显而易见的修改旨在落入所附权利要求书的范围内。

Claims (20)

1.一种方法，包括：
选择基本上管状的编织物，所述基本上管状的编织物包括：第一端部、第二端部、在所述第一端部和所述第二端部之间的长度、从所述第一端部延伸的第一部分和从所述第二端部延伸的第二部分，使得所述管状编织物能够成形为包括沿所述长度的基本上均匀的圆周的单层圆柱形形状、所述第一部分中的第一编织角和所述第二部分中的第二编织角，所述第二编织角的测量值小于所述第一编织角；
通过微导管将所述管状编织物递送到动脉瘤中；
使所述编织物的所述第一部分膨胀以与所述动脉瘤的壁并置；
在靠近所述动脉瘤的颈部处形成所述编织物的近侧翻转部；
使所述编织物的翻转的部分膨胀以将所述第一部分压到所述动脉瘤的壁；
在靠近所述动脉瘤的壁的远侧部分处形成所述编织物的远侧翻转部，使得翻转的部分从所述近侧翻转部延伸到所述远侧翻转部；以及
将所述编织物的所述第二部分定位在所述翻转的部分内。
2.根据权利要求1所述的方法，其特征在于，选择所述基本上管状的编织物还包括将所述管状编织物选择成使得所述单层圆柱形形状还包括从所述第一部分延伸到所述第二部分的连续减小的编织角。
3.根据权利要求1所述的方法，其特征在于，定位所述编织物的所述第二部分还包括使所述编织物的所述第二部分变平成条带形状并且使所述条带形状在所述翻转的部分内成环。
4.根据权利要求1所述的方法，其特征在于，还包括：
使所述编织物成形以在所述翻转的部分内形成圆顶，所述圆顶定位为靠近所述动脉瘤的壁的所述远侧部分。
5. 根据权利要求1所述的方法，其特征在于，还包括：
使所述编织物在靠近所述远侧翻转部处扭曲；以及
使所述编织物膨胀以在所述翻转的部分内形成囊。
6.根据权利要求1所述的方法，其特征在于，递送所述管状编织物还包括递送呈单层管状形状的所述管状编织物，使得所述第一端部相对于所述第二端部定位在远侧方向上。
7.根据权利要求1所述的方法，其特征在于，还包括：
选择栓塞性线圈；
将所述栓塞性线圈定位成使得其在靠近所述编织物的所述第二端部处附连到所述管状编织物；
通过所述微导管将所述栓塞性线圈递送到所述动脉瘤；以及
将所述栓塞性线圈定位在所述翻转的部分内。
8.一种植入物，包括：
基本上管状的编织物，其能够成形为单层圆柱形形状并且能够移动成植入形状，所述编织物包括：
第一端部；
第二端部；
可从所述第一端部到所述第二端部测量的长度；
从所述第一端部延伸的第一部分；
从所述第二端部延伸的第二部分；
在所述单层圆柱形形状中，沿所述长度的基本上均匀的圆周、在所述第一部分中的第一编织角和在所述第二部分中的第二编织角，所述第二编织角的测量值小于所述第一编织角；以及
在所述植入形状中，所述第一部分被定位成与动脉瘤壁并置，翻转部囊被定位成将所述第一部分压到所述动脉瘤壁，并且所述第二部分被定位在所述翻转部囊内。
9.根据权利要求8所述的植入物，其特征在于，
在所述单层圆柱形形状中，所述编织物包括从所述第一部分延伸到所述第二部分的连续减小的编织角。
10.根据权利要求8所述的植入物，其特征在于，
在所述植入形状中，所述编织物的所述第二部分的至少一部分在所述翻转的部分内成环。
11.根据权利要求8所述的植入物，其特征在于，
在所述植入形状中，所述第二部分被定位成将所述翻转的部分压到所述第一部分。
12.根据权利要求8所述的植入物，其特征在于，
在所述植入形状中，内囊被定位成将所述翻转部囊压到所述第一部分，所述编织物包括将所述内囊和所述翻转部囊分开的翻转部，并且所述编织物在靠近所述翻转部处扭曲。
13. 根据权利要求8所述的植入物，其特征在于，
当所述编织物呈所述单层管状形状时，所述编织物的尺寸被设定成使其通过微导管被递送到动脉瘤，并且
其中所述编织物能够从所述单层管状形状移动成所述植入形状。
14.根据权利要求8所述的植入物，其特征在于，还包括：
栓塞性线圈，所述栓塞性线圈在靠近所述编织物的所述第二端部处附连到所述管状编织物，
其中在所述植入形状中，所述编织物被成形为允许所述栓塞性线圈定位在所述翻转部囊内。
15.一种植入物，包括：
基本上管状的编织物，其包括第一端部、第二端部和预定形状，所述管状编织物能够移动成植入形状，所述植入形状的尺寸被设定成使其定位在动脉瘤囊中，
在所述预定形状中，所述管状编织物包括：第一翻转部、从所述第一端部延伸到所述第一翻转部的外部节段、第二翻转部、从所述第一翻转部延伸到所述第二翻转部的中间节段、以及从所述第二翻转部延伸到所述第二端部的内部节段，使得所述外部节段至少部分地围绕所述中间节段，并且所述中间节段至少部分地围绕所述内部节段，并且
在所述植入形状中，所述管状编织物的对应于在所述预定形状中的所述内部节段的至少一部分塌缩成条带形状并且定位在对应于在所述预定形状中的所述中间节段的翻转部囊中。
16. 根据权利要求15所述的植入物，其特征在于，
所述管状编织物能够成形为单层圆柱形形状，并且
其中在所述单层圆柱形形状中，所述编织物包括在所述第一端部和所述第二端部之间的基本上均匀的圆周、从所述第一端部延伸的所述编织物的第一部分中的第一编织角以及从所述第二端部延伸的所述编织物的第二部分中的第二编织角，所述第二编织角的测量值小于所述第一编织角。
17.根据权利要求16所述的植入物，其特征在于，在所述单层圆柱形形状中，所述编织物包括从所述第一部分延伸到所述第二部分的连续减小的编织角。
18.根据权利要求16所述的植入物，其特征在于，在所述单层管状形状中，所述编织物的尺寸被设定成使其通过微导管被递送到动脉瘤。
19.根据权利要求15所述的植入物，其特征在于，还包括：
栓塞性线圈，所述栓塞性线圈在靠近所述编织物的所述第二端部处附连到所述管状编织物。
20. 根据权利要求15所述的植入物，其特征在于，
在所述预定形状中，所述管状编织物包括在所述内部节段中的位置处的编织角的陡变，并且
其中从所述第二翻转部延伸的所述内部节段的远侧部分具有比从所述编织物的所述第二端部延伸的所述内部节段的近侧部分更大的编织角。
CN202011401173.6A 2019-12-05 2020-12-04 具有高度柔性填充材料的囊内翻转编织物 Withdrawn CN112914656A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/703973 2019-12-05
US16/703,973 US11602350B2 (en) 2019-12-05 2019-12-05 Intrasaccular inverting braid with highly flexible fill material

Publications (1)

Publication Number Publication Date
CN112914656A true CN112914656A (zh) 2021-06-08

Family

ID=73726734

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011401173.6A Withdrawn CN112914656A (zh) 2019-12-05 2020-12-04 具有高度柔性填充材料的囊内翻转编织物

Country Status (5)

Country Link
US (2) US11602350B2 (zh)
EP (1) EP3831316A3 (zh)
JP (1) JP2021087772A (zh)
KR (1) KR20210070916A (zh)
CN (1) CN112914656A (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11357511B2 (en) 2008-05-01 2022-06-14 Aneuclose Llc Intrasacular aneurysm occlusion device with globular first configuration and bowl-shaped second configuration
US12004750B2 (en) 2008-05-01 2024-06-11 Aneuclose Llc Methods for creating an expandable two-part intrasacular aneurysm occlusion device from a tubular mesh
US11583289B2 (en) 2008-05-01 2023-02-21 Aneuclose Llc Aneurysm-occluding mesh ribbon with a series of loops or segments having distal-to-proximal variation in size, shape, and/or orientation
US11471164B2 (en) 2008-05-01 2022-10-18 Aneuclose Llc Methods of occluding a cerebral aneurysm by inserting embolic members or material into an intrasacular implant
US11202636B2 (en) 2019-05-25 2021-12-21 Galaxy Therapeutics Inc. Systems and methods for treating aneurysms
WO2022164957A1 (en) 2021-01-27 2022-08-04 Galaxy Therapeutics, Inc. Systems and methods for treating aneurysms
KR102442152B1 (ko) 2021-06-01 2022-09-08 주식회사 다스 시트의 워크인 장치

Family Cites Families (405)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2849002A (en) 1956-03-12 1958-08-26 Vincent J Oddo Haemostatic catheter
US3480017A (en) 1966-04-27 1969-11-25 Wallace B Shute Cervical dilator
US4085757A (en) 1976-04-29 1978-04-25 P Pevsner Miniature balloon catheter method and apparatus
US4282875A (en) 1979-01-24 1981-08-11 Serbinenko Fedor A Occlusive device
US4395806A (en) 1980-05-08 1983-08-02 Sorenson Research Co., Inc. Method of manufacturing a detachable balloon catheter assembly
US4364392A (en) 1980-12-04 1982-12-21 Wisconsin Alumni Research Foundation Detachable balloon catheter
US4545367A (en) 1982-07-16 1985-10-08 Cordis Corporation Detachable balloon catheter and method of use
US4517979A (en) 1983-07-14 1985-05-21 Cordis Corporation Detachable balloon catheter
WO1988003817A1 (en) 1986-11-29 1988-06-02 Terumo Kabushiki Kaisha Catheter equipped with balloon
US4836204A (en) 1987-07-06 1989-06-06 Landymore Roderick W Method for effecting closure of a perforation in the septum of the heart
US5067489A (en) 1988-08-16 1991-11-26 Flexmedics Corporation Flexible guide with safety tip
FR2641692A1 (fr) 1989-01-17 1990-07-20 Nippon Zeon Co Bouchon de fermeture d'une breche pour application medicale et dispositif pour bouchon de fermeture l'utilisant
US4991602A (en) 1989-06-27 1991-02-12 Flexmedics Corporation Flexible guide wire with safety tip
US5065772A (en) 1989-10-13 1991-11-19 Inamed Corporation Inflatable cerivical pessary
US6425893B1 (en) 1990-03-13 2002-07-30 The Regents Of The University Of California Method and apparatus for fast electrolytic detachment of an implant
US5122136A (en) 1990-03-13 1992-06-16 The Regents Of The University Of California Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
JPH0546421Y2 (zh) 1990-08-23 1993-12-06
US5025060A (en) 1990-10-15 1991-06-18 Kansai Paint Co., Ltd. Dispersion of fine particles of a polymer
CA2079417C (en) 1991-10-28 2003-01-07 Lilip Lau Expandable stents and method of making same
DK0617594T3 (da) 1991-12-12 1998-02-02 Target Therapeutics Inc Adskillelig udstøderkarokklusionsspiralkonstruktion med sammenlåsningskobling
US5261916A (en) 1991-12-12 1993-11-16 Target Therapeutics Detachable pusher-vasoocclusive coil assembly with interlocking ball and keyway coupling
US5342387A (en) 1992-06-18 1994-08-30 American Biomed, Inc. Artificial support for a blood vessel
US5350397A (en) 1992-11-13 1994-09-27 Target Therapeutics, Inc. Axially detachable embolic coil assembly
US5334210A (en) 1993-04-09 1994-08-02 Cook Incorporated Vascular occlusion assembly
US5624449A (en) 1993-11-03 1997-04-29 Target Therapeutics Electrolytically severable joint for endovascular embolic devices
US5423829A (en) 1993-11-03 1995-06-13 Target Therapeutics, Inc. Electrolytically severable joint for endovascular embolic devices
JP2605559Y2 (ja) 1993-12-21 2000-07-24 株式会社パイオラックス 管状器官の治療具
ES2185707T5 (es) 1994-07-08 2007-05-01 Ev3 Inc. Dispositivo de filtraje intravascular.
US5846261A (en) 1994-07-08 1998-12-08 Aga Medical Corp. Percutaneous catheter directed occlusion devices
US5814062A (en) 1994-12-22 1998-09-29 Target Therapeutics, Inc. Implant delivery assembly with expandable coupling/decoupling mechanism
IL116561A0 (en) 1994-12-30 1996-03-31 Target Therapeutics Inc Severable joint for detachable devices placed within the body
US5634936A (en) 1995-02-06 1997-06-03 Scimed Life Systems, Inc. Device for closing a septal defect
US5645558A (en) 1995-04-20 1997-07-08 Medical University Of South Carolina Anatomically shaped vasoocclusive device and method of making the same
RU2157146C2 (ru) 1995-06-13 2000-10-10 ВИЛЬЯМ КУК Европа, A/S Устройство для имплантации в сосудах и полых органах (его варианты)
US6168622B1 (en) 1996-01-24 2001-01-02 Microvena Corporation Method and apparatus for occluding aneurysms
US5733294A (en) 1996-02-28 1998-03-31 B. Braun Medical, Inc. Self expanding cardiovascular occlusion device, method of using and method of making the same
US5853422A (en) 1996-03-22 1998-12-29 Scimed Life Systems, Inc. Apparatus and method for closing a septal defect
US6949116B2 (en) 1996-05-08 2005-09-27 Carag Ag Device for plugging an opening such as in a wall of a hollow or tubular organ including biodegradable elements
US5964797A (en) * 1996-08-30 1999-10-12 Target Therapeutics, Inc. Electrolytically deployable braided vaso-occlusion device
US5941249A (en) 1996-09-05 1999-08-24 Maynard; Ronald S. Distributed activator for a two-dimensional shape memory alloy
US6007573A (en) 1996-09-18 1999-12-28 Microtherapeutics, Inc. Intracranial stent and method of use
US6254628B1 (en) 1996-12-09 2001-07-03 Micro Therapeutics, Inc. Intracranial stent
US5951599A (en) 1997-07-09 1999-09-14 Scimed Life Systems, Inc. Occlusion system for endovascular treatment of an aneurysm
US5928260A (en) 1997-07-10 1999-07-27 Scimed Life Systems, Inc. Removable occlusion system for aneurysm neck
DE69835958T2 (de) 1997-08-04 2007-02-15 Boston Scientific Ltd., Barbados Okklussionssystem zum ausbessern eines aneurysmas
US6063070A (en) 1997-08-05 2000-05-16 Target Therapeutics, Inc. Detachable aneurysm neck bridge (II)
GB9716497D0 (en) 1997-08-05 1997-10-08 Bridport Gundry Plc Occlusion device
WO1999008607A1 (en) 1997-08-05 1999-02-25 Boston Scientific Limited Detachable aneurysm neck bridge
US6086577A (en) 1997-08-13 2000-07-11 Scimed Life Systems, Inc. Detachable aneurysm neck bridge (III)
US5916235A (en) 1997-08-13 1999-06-29 The Regents Of The University Of California Apparatus and method for the use of detachable coils in vascular aneurysms and body cavities
US6146373A (en) 1997-10-17 2000-11-14 Micro Therapeutics, Inc. Catheter system and method for injection of a liquid embolic composition and a solidification agent
US6036720A (en) 1997-12-15 2000-03-14 Target Therapeutics, Inc. Sheet metal aneurysm neck bridge
ES2343228T3 (es) 1998-02-10 2010-07-26 Ethicon Endo-Surgery, Inc. Aparato de oclusion, de anclaje, de tensionado o de direccion por flujo.
US6063100A (en) 1998-03-10 2000-05-16 Cordis Corporation Embolic coil deployment system with improved embolic coil
US6379374B1 (en) 1998-10-22 2002-04-30 Cordis Neurovascular, Inc. Small diameter embolic coil hydraulic deployment system
US5925060A (en) 1998-03-13 1999-07-20 B. Braun Celsa Covered self-expanding vascular occlusion device
EP1071491A4 (en) 1998-03-30 2004-10-20 Univ Virginia STOP OF THE FLOW, DOUBLE BALLOON TECHNIQUE ALLOWING THE OCCLUSION OF ANNEVRISMS OR BLOOD VESSELS
US6168615B1 (en) 1998-05-04 2001-01-02 Micrus Corporation Method and apparatus for occlusion and reinforcement of aneurysms
SE514546C2 (sv) 1998-05-18 2001-03-12 Allgon Ab Ett antennsystem och en radiokommunikationsanordning innefattande ett antennsystem
US6463317B1 (en) 1998-05-19 2002-10-08 Regents Of The University Of Minnesota Device and method for the endovascular treatment of aneurysms
US6113609A (en) 1998-05-26 2000-09-05 Scimed Life Systems, Inc. Implantable tissue fastener and system for treating gastroesophageal reflux disease
US5935148A (en) 1998-06-24 1999-08-10 Target Therapeutics, Inc. Detachable, varying flexibility, aneurysm neck bridge
US6096175A (en) 1998-07-17 2000-08-01 Micro Therapeutics, Inc. Thin film stent
AU5905599A (en) 1998-09-04 2000-03-27 Boston Scientific Limited Detachable aneurysm neck closure patch
US7410482B2 (en) 1998-09-04 2008-08-12 Boston Scientific-Scimed, Inc. Detachable aneurysm neck bridge
US6551340B1 (en) 1998-10-09 2003-04-22 Board Of Regents The University Of Texas System Vasoocclusion coil device having a core therein
US7128073B1 (en) 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US7044134B2 (en) 1999-11-08 2006-05-16 Ev3 Sunnyvale, Inc Method of implanting a device in the left atrial appendage
US8016852B2 (en) 1998-11-10 2011-09-13 Stryker Corporation Bioactive components for incorporation with vaso-occlusive members
US6569179B2 (en) 1998-11-10 2003-05-27 Scimed Life Systems, Inc. Bioactive three loop coil
US6080183A (en) 1998-11-24 2000-06-27 Embol-X, Inc. Sutureless vessel plug and methods of use
EP1576937B1 (en) 1999-02-01 2012-10-31 Board Of Regents, The University Of Texas System Woven intravascular devices and methods for making the same and apparatus for delvery of the same
US6428558B1 (en) 1999-03-10 2002-08-06 Cordis Corporation Aneurysm embolization device
US6375606B1 (en) 1999-03-17 2002-04-23 Stereotaxis, Inc. Methods of and apparatus for treating vascular defects
US6858034B1 (en) 1999-05-20 2005-02-22 Scimed Life Systems, Inc. Stent delivery system for prevention of kinking, and method of loading and using same
US6379329B1 (en) 1999-06-02 2002-04-30 Cordis Neurovascular, Inc. Detachable balloon embolization device and method
US6375668B1 (en) 1999-06-02 2002-04-23 Hanson S. Gifford Devices and methods for treating vascular malformations
US6689150B1 (en) 1999-10-27 2004-02-10 Atritech, Inc. Filter apparatus for ostium of left atrial appendage
US6551303B1 (en) 1999-10-27 2003-04-22 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6994092B2 (en) 1999-11-08 2006-02-07 Ev3 Sunnyvale, Inc. Device for containing embolic material in the LAA having a plurality of tissue retention structures
US6331184B1 (en) 1999-12-10 2001-12-18 Scimed Life Systems, Inc. Detachable covering for an implantable medical device
US6350270B1 (en) 2000-01-24 2002-02-26 Scimed Life Systems, Inc. Aneurysm liner
US6391037B1 (en) 2000-03-02 2002-05-21 Prodesco, Inc. Bag for use in the intravascular treatment of saccular aneurysms
US6346117B1 (en) 2000-03-02 2002-02-12 Prodesco, Inc. Bag for use in the intravascular treatment of saccular aneurysms
US7153323B1 (en) 2000-06-30 2006-12-26 Boston Scientific Scimed, Inc. Aneurysm liner with multi-segment extender
DE60141653D1 (de) 2000-07-21 2010-05-06 Spineology Group Llc Eine dehnbare, poröse netzbeutel-vorrichtung und seine nutzung in der knochenchirugie
US6855154B2 (en) 2000-08-11 2005-02-15 University Of Louisville Research Foundation, Inc. Endovascular aneurysm treatment device and method
CA2409104A1 (en) 2000-10-11 2002-04-18 Micro Therapeutics, Inc. Methods for treating aneurysms
WO2002069783A2 (en) 2000-10-24 2002-09-12 Concentric Medical, Inc. Device and methods for treating vascular malformations
US6547804B2 (en) 2000-12-27 2003-04-15 Scimed Life Systems, Inc. Selectively permeable highly distensible occlusion balloon
US6866677B2 (en) 2001-04-03 2005-03-15 Medtronic Ave, Inc. Temporary intraluminal filter guidewire and methods of use
US20020147497A1 (en) 2001-04-06 2002-10-10 Integrated Vascular Systems, Inc. Methods for treating spinal discs
US20020188314A1 (en) 2001-06-07 2002-12-12 Microvena Corporation Radiopaque distal embolic protection device
US6454780B1 (en) 2001-06-21 2002-09-24 Scimed Life Systems, Inc. Aneurysm neck obstruction device
US20030181927A1 (en) 2001-06-21 2003-09-25 Wallace Michael P. Aneurysm neck obstruction device
US6964671B2 (en) 2001-06-28 2005-11-15 Cordis Neurovascular, Inc. Method and apparatus for placing a medical agent into a vessel of the body
US6572628B2 (en) 2001-06-28 2003-06-03 Cordis Neurovascular, Inc. Method and apparatus for placing a medical agent into a vessel of the body
US8715312B2 (en) 2001-07-20 2014-05-06 Microvention, Inc. Aneurysm treatment device and method of use
US7572288B2 (en) 2001-07-20 2009-08-11 Microvention, Inc. Aneurysm treatment device and method of use
US8252040B2 (en) 2001-07-20 2012-08-28 Microvention, Inc. Aneurysm treatment device and method of use
US20030028209A1 (en) 2001-07-31 2003-02-06 Clifford Teoh Expandable body cavity liner device
US6802851B2 (en) 2001-09-20 2004-10-12 Gordia Neurovascular, Inc. Stent aneurysm embolization method using collapsible member and embolic coils
US6811560B2 (en) 2001-09-20 2004-11-02 Cordis Neurovascular, Inc. Stent aneurysm embolization method and device
DE60224817T2 (de) 2001-11-09 2009-02-19 Rubicon Medical, Inc., Sandy Stent-ablagevorrichtung mit embolieschutz
JP2003190175A (ja) 2001-11-15 2003-07-08 Cordis Neurovascular Inc 動脈瘤を密閉するための動脈瘤頚部プラグ
JP4429589B2 (ja) 2001-11-15 2010-03-10 コーディス・ニューロバスキュラー・インコーポレイテッド 閉塞部材を用いる動脈瘤塞栓装置
US20060292206A1 (en) 2001-11-26 2006-12-28 Kim Steven W Devices and methods for treatment of vascular aneurysms
ATE378019T1 (de) 2002-03-05 2007-11-15 Salviac Ltd System aus embolischem filter und rückziehschlinge
US6773448B2 (en) 2002-03-08 2004-08-10 Ev3 Inc. Distal protection devices having controllable wire motion
US20030176884A1 (en) 2002-03-12 2003-09-18 Marwane Berrada Everted filter device
JP4465192B2 (ja) 2002-03-15 2010-05-19 エヌエムティー メディカル， インコーポレイティッド 移植物の配置において有用な結合システム
US7695488B2 (en) 2002-03-27 2010-04-13 Boston Scientific Scimed, Inc. Expandable body cavity liner device
US20030195553A1 (en) 2002-04-12 2003-10-16 Scimed Life Systems, Inc. System and method for retaining vaso-occlusive devices within an aneurysm
US6833003B2 (en) 2002-06-24 2004-12-21 Cordis Neurovascular Expandable stent and delivery system
US20040034386A1 (en) 2002-08-19 2004-02-19 Michael Fulton Aneurysm stent
US20040044391A1 (en) 2002-08-29 2004-03-04 Stephen Porter Device for closure of a vascular defect and method of treating the same
US8075585B2 (en) 2002-08-29 2011-12-13 Stryker Corporation Device and method for treatment of a vascular defect
US7229454B2 (en) 2003-01-07 2007-06-12 Boston Scientific Scimed, Inc. Occlusive cinching devices and methods of use
US20040254594A1 (en) 2003-01-24 2004-12-16 Arthur Alfaro Cardiac defect occlusion device
US7744583B2 (en) 2003-02-03 2010-06-29 Boston Scientific Scimed Systems and methods of de-endothelialization
US7293562B2 (en) 2003-03-27 2007-11-13 Cierra, Inc. Energy based devices and methods for treatment of anatomic tissue defects
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
TWI221091B (en) 2003-04-18 2004-09-21 A Spine Holding Group Corp Spine filling device
US7597704B2 (en) 2003-04-28 2009-10-06 Atritech, Inc. Left atrial appendage occlusion device with active expansion
EP1633275B1 (en) 2003-05-15 2017-11-29 Biomerix Corporation Reticulated elastomeric matrices, their manufacture and use in implantable devices
US7093527B2 (en) 2003-06-10 2006-08-22 Surpass Medical Ltd. Method and apparatus for making intraluminal implants and construction particularly useful in such method and apparatus
US7309345B2 (en) 2003-07-25 2007-12-18 Boston Scientific-Scimed, Inc. Method and system for delivering an implant utilizing a lumen reducing member
US7735493B2 (en) 2003-08-15 2010-06-15 Atritech, Inc. System and method for delivering a left atrial appendage containment device
DE10338702B9 (de) 2003-08-22 2007-04-26 Occlutech Gmbh Occlusioninstrument
US7371228B2 (en) 2003-09-19 2008-05-13 Medtronic Vascular, Inc. Delivery of therapeutics to treat aneurysms
US7232461B2 (en) 2003-10-29 2007-06-19 Cordis Neurovascular, Inc. Neck covering device for an aneurysm
EP1689457A2 (en) 2003-11-10 2006-08-16 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
US8231649B2 (en) 2004-01-20 2012-07-31 Boston Scientific Scimed, Inc. Retrievable blood clot filter with retractable anchoring members
JP2007519498A (ja) 2004-01-30 2007-07-19 エヌエムティー メディカル， インコーポレイティッド 心臓開口部の閉鎖のためのデバイス、システム、および方法
US9039724B2 (en) 2004-03-19 2015-05-26 Aga Medical Corporation Device for occluding vascular defects
US7678129B1 (en) 2004-03-19 2010-03-16 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US20050228434A1 (en) 2004-03-19 2005-10-13 Aga Medical Corporation Multi-layer braided structures for occluding vascular defects
US8777974B2 (en) 2004-03-19 2014-07-15 Aga Medical Corporation Multi-layer braided structures for occluding vascular defects
BE1016067A3 (fr) 2004-06-03 2006-02-07 Frid Noureddine Endoprothese luminale pour occlusion d'anevrisme et procede de fabrication d'une telle endoprothese.
US9308382B2 (en) 2004-06-10 2016-04-12 Medtronic Urinary Solutions, Inc. Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
US8048145B2 (en) 2004-07-22 2011-11-01 Endologix, Inc. Graft systems having filling structures supported by scaffolds and methods for their use
EP1827250B1 (en) 2004-08-31 2018-05-16 Cook Medical Technologies LLC Device for treating an aneurysm
US9655633B2 (en) 2004-09-10 2017-05-23 Penumbra, Inc. System and method for treating ischemic stroke
US7244270B2 (en) 2004-09-16 2007-07-17 Evera Medical Systems and devices for soft tissue augmentation
JP2008513141A (ja) 2004-09-17 2008-05-01 コーディス・ニューロバスキュラー・インコーポレイテッド 動脈瘤または血管を施栓する薄膜金属器具
JP2008515467A (ja) 2004-09-17 2008-05-15 コーディス・ニューロバスキュラー・インコーポレイテッド 塞栓性メッシュリボンを備えた血管閉塞器具
US8357180B2 (en) 2004-09-17 2013-01-22 Codman & Shurtleff, Inc. Thin film metallic device for plugging aneurysms or vessels
EP1804719A2 (en) 2004-09-22 2007-07-11 Lee R. Guterman Cranial aneurysm treatment arrangement
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
AU2005304459B2 (en) 2004-11-09 2011-10-13 Stryker European Holdings I, Llc Vaso-occlusive devices comprising complex-shape proximal portion and smaller diameter distal portion
US20060106421A1 (en) 2004-11-16 2006-05-18 Clifford Teoh Expansible neck bridge
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US9545300B2 (en) 2004-12-22 2017-01-17 W. L. Gore & Associates, Inc. Filament-wound implantable devices
US20060155367A1 (en) 2005-01-07 2006-07-13 Hines Richard A Micro-pleated stent assembly
US20060155323A1 (en) 2005-01-07 2006-07-13 Porter Stephen C Intra-aneurysm devices
WO2006078988A2 (en) 2005-01-21 2006-07-27 Loubert Suddaby Aneurysm repair method and apparatus
US8025668B2 (en) 2005-04-28 2011-09-27 C. R. Bard, Inc. Medical device removal system
US7985238B2 (en) 2005-06-02 2011-07-26 Codman & Shurtleff, Inc. Embolic coil delivery system with spring wire release mechanism
US7377932B2 (en) 2005-06-02 2008-05-27 Cordis Neurovascular, Inc. Embolic coil delivery system with mechanical release mechanism
US9636115B2 (en) 2005-06-14 2017-05-02 Stryker Corporation Vaso-occlusive delivery device with kink resistant, flexible distal end
EP2759276A1 (en) 2005-06-20 2014-07-30 Medtronic Ablation Frontiers LLC Ablation catheter
AU2006304660B2 (en) 2005-10-19 2013-10-24 Pulsar Vascular, Inc. Methods and systems for endovascularly clipping and repairing lumen and tissue defects
US8545530B2 (en) 2005-10-19 2013-10-01 Pulsar Vascular, Inc. Implantable aneurysm closure systems and methods
US8066036B2 (en) 2005-11-17 2011-11-29 Microvention, Inc. Three-dimensional complex coil
WO2007076480A2 (en) 2005-12-23 2007-07-05 Levy Elad I Bifurcated aneurysm treatment arrangement
US20070167876A1 (en) 2006-01-17 2007-07-19 Euteneuer Charles L Occluding guidewire and methods
US20070186933A1 (en) 2006-01-17 2007-08-16 Pulmonx Systems and methods for delivering flow restrictive element to airway in lungs
US7744652B2 (en) 2006-01-23 2010-06-29 Hesham Morsi Aneurysm sealing device
CN101049266B (zh) 2006-04-03 2010-11-17 孟坚 医疗用闭塞器械及其制造方法
CN102813541A (zh) 2006-03-14 2012-12-12 塞茂普特克斯公司 动脉瘤弹簧圈输送系统
AU2007309715A1 (en) 2006-03-24 2008-05-02 Biomerix Corp Self-expandable endovascular device for aneurysm occlusion
US9757260B2 (en) 2006-03-30 2017-09-12 Medtronic Vascular, Inc. Prosthesis with guide lumen
US20070239206A1 (en) 2006-03-31 2007-10-11 Shelton Frederick E Iv Suture with adhesive/sealant delivery mechanism
US9615832B2 (en) 2006-04-07 2017-04-11 Penumbra, Inc. Aneurysm occlusion system and method
US20070288083A1 (en) 2006-05-12 2007-12-13 Hines Richard A Exclusion Device and System For Delivery
EP2027729A2 (en) 2006-06-15 2009-02-25 MicroVention, Inc. Embolization device constructed from expansible polymer
US8062325B2 (en) 2006-07-31 2011-11-22 Codman & Shurtleff, Inc. Implantable medical device detachment system and methods of using the same
US20080097401A1 (en) 2006-09-22 2008-04-24 Trapp Benjamin M Cerebral vasculature device
DE102006050385A1 (de) 2006-10-05 2008-04-10 pfm Produkte für die Medizin AG Implantierbare Einrichtung
US20080103505A1 (en) 2006-10-26 2008-05-01 Hendrik Raoul Andre Fransen Containment device for site-specific delivery of a therapeutic material and methods of use
WO2008063455A1 (en) 2006-11-13 2008-05-29 Hines Richard A Over-the wire exclusion device and system for delivery
EP2263605A1 (en) 2006-11-20 2010-12-22 SeptRx, Inc. Device and method for preventing the undesired passage of emboli from a venous blood pool to an arterial blood pool
US20080281350A1 (en) 2006-12-13 2008-11-13 Biomerix Corporation Aneurysm Occlusion Devices
US11166703B2 (en) 2007-01-23 2021-11-09 Cvdevices, Llc Devices, systems, and methods for atrial appendage occlusion using light cure
ES2856081T3 (es) 2007-04-16 2021-09-27 Occlutech Holding Ag Oclusor para la oclusión de una orejuela auricular y procedimiento de producción del mismo
AU2008254770A1 (en) 2007-05-18 2008-11-27 Stryker Corporation Medical implant detachment systems
WO2008150346A1 (en) 2007-05-31 2008-12-11 Rex Medical, L.P. Closure device for left atrial appendage
EP2157937B1 (en) 2007-06-04 2017-03-22 Sequent Medical, Inc. Devices for treatment of vascular defects
US8034061B2 (en) 2007-07-12 2011-10-11 Aga Medical Corporation Percutaneous catheter directed intravascular occlusion devices
US8361138B2 (en) 2007-07-25 2013-01-29 Aga Medical Corporation Braided occlusion device having repeating expanded volume segments separated by articulation segments
US8500773B2 (en) 2007-08-01 2013-08-06 Boston Scientific Scimed, Inc. Spring detach joint for delivering a detachable implantable device
CN101842056B (zh) 2007-08-02 2013-07-17 奥特鲁泰克控股有限公司 医用可植入装置的制造方法及医用可植入装置
US20090082803A1 (en) 2007-09-26 2009-03-26 Aga Medical Corporation Braided vascular devices having no end clamps
US9414842B2 (en) 2007-10-12 2016-08-16 St. Jude Medical, Cardiology Division, Inc. Multi-component vascular device
US8066757B2 (en) 2007-10-17 2011-11-29 Mindframe, Inc. Blood flow restoration and thrombus management methods
BRPI0821070B1 (pt) 2007-12-21 2018-10-23 Microvention Inc dispositivo para implantação e método para a preparação de um filamento de hidrogel para implantação em um animal
US9259225B2 (en) 2008-02-19 2016-02-16 St. Jude Medical, Cardiology Division, Inc. Medical devices for treating a target site and associated method
US9138213B2 (en) 2008-03-07 2015-09-22 W.L. Gore & Associates, Inc. Heart occlusion devices
JP4719757B2 (ja) 2008-03-19 2011-07-06 シスメックス株式会社 生体成分分析装置、生体成分分析装置の反応カートリッジおよび生体成分分析装置の抽出カートリッジ
US8974518B2 (en) 2008-03-25 2015-03-10 Medtronic Vascular, Inc. Eversible branch stent-graft and deployment method
DE102008015781B4 (de) 2008-03-26 2011-09-29 Malte Neuss Vorrichtung zum Verschluss von Defekten im Gefäßsystem
EP2387959B1 (en) 2008-04-21 2013-11-13 Covidien LP Braid-ball embolic devices and delivery systems
EP2310077A1 (en) 2008-04-30 2011-04-20 Medtronic, Inc. Techniques for placing medical leads for electrical stimulation of nerve tissue
EP2280755A1 (en) 2008-05-01 2011-02-09 Aneuclose LLC Aneurysm occlusion device
US10716573B2 (en) * 2008-05-01 2020-07-21 Aneuclose Janjua aneurysm net with a resilient neck-bridging portion for occluding a cerebral aneurysm
US11464518B2 (en) 2008-05-01 2022-10-11 Aneuclose Llc Proximal concave neck bridge with central lumen and distal net for occluding cerebral aneurysms
BRPI0911923B8 (pt) 2008-05-02 2021-06-22 Sequent Medical Inc dispositivo para tratamento de um aneurisma cerebral
US8454632B2 (en) 2008-05-12 2013-06-04 Xlumena, Inc. Tissue anchor for securing tissue layers
US8070694B2 (en) 2008-07-14 2011-12-06 Medtronic Vascular, Inc. Fiber based medical devices and aspiration catheters
US8333796B2 (en) 2008-07-15 2012-12-18 Penumbra, Inc. Embolic coil implant system and implantation method
US9351715B2 (en) 2008-07-24 2016-05-31 St. Jude Medical, Cardiology Division, Inc. Multi-layered medical device for treating a target site and associated method
US9232992B2 (en) 2008-07-24 2016-01-12 Aga Medical Corporation Multi-layered medical device for treating a target site and associated method
US8262692B2 (en) 2008-09-05 2012-09-11 Merlin Md Pte Ltd Endovascular device
US20100069948A1 (en) 2008-09-12 2010-03-18 Micrus Endovascular Corporation Self-expandable aneurysm filling device, system and method of placement
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8992568B2 (en) 2008-10-20 2015-03-31 Neil Duggal Systems and methods for cerebrospinal fluid repair
WO2010088561A2 (en) 2009-01-30 2010-08-05 Kfx Medical Corporation System and method for attaching soft tissue to bone
AU2010236337B2 (en) 2009-04-15 2015-01-29 Microvention, Inc. Implant delivery system
WO2010120694A1 (en) 2009-04-16 2010-10-21 Boston Scientific Scimed, Inc. Electrical contact for occlusive device delivery system
WO2010134914A1 (en) 2009-05-20 2010-11-25 University Of Miami Spherical helix embolic coils for the treatment of cerebral aneurysms
US8758423B2 (en) 2009-06-18 2014-06-24 Graftcraft I Goteborg Ab Device and method for treating ruptured aneurysms
US20120010644A1 (en) 2009-07-09 2012-01-12 Sideris Eleftherios B Method and apparatus for occluding a physiological opening
EP2453940A2 (en) 2009-07-13 2012-05-23 Yissum Research Development Company of The Hebrew University of Jerusalem Intraluminal polymeric devices for the treatment of aneurysms
WO2011038017A1 (en) 2009-09-22 2011-03-31 Penumbra, Inc. Manual actuation system for deployment of implant
BR112012010758A2 (pt) 2009-11-05 2019-09-24 Sequent Medical Inc dispositivos filamentares de camadas múltiplas para tratamento de defeitos vasculares
WO2011057277A2 (en) 2009-11-09 2011-05-12 Nfocus Neuromedical, Inc. Braid ball embolic device features
US9814562B2 (en) 2009-11-09 2017-11-14 Covidien Lp Interference-relief type delivery detachment systems
US8226657B2 (en) 2009-11-10 2012-07-24 Carefusion 207, Inc. Systems and methods for vertebral or other bone structure height restoration and stabilization
US8734458B2 (en) 2009-12-07 2014-05-27 Globus Medical, Inc. Methods and apparatus for treating vertebral fractures
DE102009058132B4 (de) 2009-12-12 2014-07-24 Bentley Surgical Gmbh Zylindrischer Okkluder zur Abdichtung hohlzylindrischer Körpergefäße
CN102188300B (zh) 2010-03-02 2014-05-28 上海微创医疗器械（集团）有限公司 一种动脉瘤手术装置
US9561125B2 (en) 2010-04-14 2017-02-07 Microvention, Inc. Implant delivery device
US8764811B2 (en) 2010-04-20 2014-07-01 Medtronic Vascular, Inc. Controlled tip release stent graft delivery system and method
ES2403009T3 (es) 2010-05-23 2013-05-13 Occlutech Holding Ag Dispositivo médico trenzado y método para su fabricación
WO2011163596A1 (en) 2010-06-25 2011-12-29 Fort Wayne Metals Research Products Corporation Biodegradable composite wire for medical devices
US8876878B2 (en) 2010-07-23 2014-11-04 Medtronic, Inc. Attachment mechanism for stent release
BR112013005429A2 (pt) 2010-09-06 2016-06-07 Nonwotecc Medical Gmbh "dispositivo para o fechamento de aberturas ou cavidades em vasos sanguíneos"
US20130066357A1 (en) 2010-09-10 2013-03-14 Maria Aboytes Devices and methods for the treatment of vascular defects
US8974512B2 (en) 2010-09-10 2015-03-10 Medina Medical, Inc. Devices and methods for the treatment of vascular defects
US8998947B2 (en) 2010-09-10 2015-04-07 Medina Medical, Inc. Devices and methods for the treatment of vascular defects
CN101933850B (zh) 2010-09-16 2012-07-18 先健科技(深圳)有限公司 封堵器及其制造方法
US8616040B2 (en) 2010-09-17 2013-12-31 Medtronic Vascular, Inc. Method of forming a drug-eluting medical device
DE102010053111B4 (de) 2010-12-01 2012-10-25 Acandis Gmbh & Co. Kg Anordnung mit einer Vorrichtung zur Zufuhr eines medizinischen Funktionselements
KR20140004679A (ko) 2010-12-20 2014-01-13 마이크로벤션, 인코포레이티드 폴리머 스텐트 및 제조방법
US20120165732A1 (en) 2010-12-23 2012-06-28 Synthes Usa, Llc Balloon catheter comprising a zero-profile tip
ES2754999T3 (es) 2011-01-17 2020-04-21 Metactive Medical Inc Dispositivo de instalación de balón metálico desprendible
US11484318B2 (en) 2011-01-17 2022-11-01 Artio Medical, Inc. Expandable body device and method of use
US8647358B2 (en) 2011-01-21 2014-02-11 Obalon Therapeutics Inc. Intragastric device
DE102011011869A1 (de) 2011-02-22 2012-08-23 Phenox Gmbh Implantat
CA2828960A1 (en) 2011-03-02 2012-09-07 Joe Michael Eskridge Endovascular closure system
US20120283768A1 (en) 2011-05-05 2012-11-08 Sequent Medical Inc. Method and apparatus for the treatment of large and giant vascular defects
US9486604B2 (en) 2011-05-12 2016-11-08 Medtronic, Inc. Packaging and preparation tray for a delivery system
WO2012158668A1 (en) 2011-05-17 2012-11-22 Stryker Corporation Method of fabricating an implantable medical device that includes one or more thin film polymer support layers
EP3741314B1 (en) 2011-05-23 2022-12-21 Covidien LP Retrieval systems
WO2012166467A1 (en) 2011-05-27 2012-12-06 Stryker Corporation Assembly for percutaneously inserting an implantable medical device, steering the device to a target location and deploying the device
DE102011102955B4 (de) 2011-05-31 2018-05-03 Acandis Gmbh & Co. Kg Medizinisches Implantat zur Anordnung eines Hohlkörpers, insbesondere eines Aneurysmas, und Verfahren zum Herstellen eines medizinischen Implantats
EP2713905B1 (en) 2011-06-03 2022-03-16 Pulsar Vascular, Inc. Systems for enclosing an anatomical opening, including shock absorbing aneurysm devices
US8764787B2 (en) 2011-06-17 2014-07-01 Aga Medical Corporation Occlusion device and associated deployment method
US20120330341A1 (en) 2011-06-22 2012-12-27 Becking Frank P Folded-Flat Aneurysm Embolization Devices
US9161837B2 (en) 2011-07-27 2015-10-20 The Cleveland Clinic Foundation Apparatus, system, and method for treating a regurgitant heart valve
US9198668B2 (en) 2011-08-04 2015-12-01 Cook Medical Technologies Llc Cerebral aneurysm closure device
US20130035665A1 (en) 2011-08-05 2013-02-07 W. L. Gore & Associates, Inc. Polymer-Based Occlusion Devices, Systems and Methods
EP2567663A1 (en) 2011-09-09 2013-03-13 Occlutech Holding AG A collapsible medical closing device, a method and a medical system for delivering an object
US8734500B2 (en) 2011-09-27 2014-05-27 DePuy Synthes Products, LLC Distal detachment mechanisms for vascular devices
US9750565B2 (en) 2011-09-30 2017-09-05 Medtronic Advanced Energy Llc Electrosurgical balloons
US8261648B1 (en) 2011-10-17 2012-09-11 Sequent Medical Inc. Braiding mechanism and methods of use
US8993831B2 (en) 2011-11-01 2015-03-31 Arsenal Medical, Inc. Foam and delivery system for treatment of postpartum hemorrhage
US9579104B2 (en) 2011-11-30 2017-02-28 Covidien Lp Positioning and detaching implants
US20150005811A1 (en) * 2012-01-06 2015-01-01 Inceptus Medical, Llc Expandable occlusion devices and methods of use
KR102189536B1 (ko) 2012-01-17 2020-12-14 아르티오 메디컬 인크. 팽창성 바디 디바이스 및 사용 방법
WO2013116860A1 (en) 2012-02-02 2013-08-08 Inceptus Medical LLC Aneurysm graft devices and methods
AU2013231845B2 (en) 2012-03-16 2017-07-06 Terumo Corporation Stent and stent delivery device
US9833625B2 (en) 2012-03-26 2017-12-05 Medtronic, Inc. Implantable medical device delivery with inner and outer sheaths
US9717421B2 (en) 2012-03-26 2017-08-01 Medtronic, Inc. Implantable medical device delivery catheter with tether
US9808255B2 (en) 2012-03-30 2017-11-07 DePuy Synthes Products, Inc. Embolic coil detachment mechanism with flexible distal member, resistive electrical heating element and shape memory polymer element
DE102012102844B4 (de) 2012-04-02 2020-03-19 Acandis Gmbh Okklusionsvorrichtung zur Implantation innerhalb eines Aneurysmas und Anordnung mit einer derartigen Okklusionsvorrichtung
US9242290B2 (en) 2012-04-03 2016-01-26 Medtronic Vascular, Inc. Method and apparatus for creating formed elements used to make wound stents
WO2013159065A1 (en) 2012-04-20 2013-10-24 Paul Lubock Expandable occlusion devices and methods of use
US9078659B2 (en) 2012-04-23 2015-07-14 Covidien Lp Delivery system with hooks for resheathability
US9700399B2 (en) 2012-04-26 2017-07-11 Medtronic Vascular, Inc. Stopper to prevent graft material slippage in a closed web stent-graft
US9549832B2 (en) 2012-04-26 2017-01-24 Medtronic Vascular, Inc. Apparatus and methods for filling a drug eluting medical device via capillary action
CA2874727A1 (en) 2012-06-04 2013-12-12 Penumbra, Inc. Aneurysm occlusion system and method
US9149190B2 (en) 2012-07-17 2015-10-06 Stryker Corporation Notification system of deviation from predefined conditions
WO2014028528A1 (en) 2012-08-13 2014-02-20 Microvention, Inc. Shaped removal device
JP6533463B2 (ja) 2012-08-22 2019-06-19 フェノックス ゲーエムベーハーＰｈｅｎｏｘ Ｇｍｂｈ インプラント
US9504476B2 (en) 2012-10-01 2016-11-29 Microvention, Inc. Catheter markers
WO2014062696A1 (en) 2012-10-15 2014-04-24 Microvention, Inc. Polymeric treatment compositions
EP2919668A2 (en) 2012-11-13 2015-09-23 Covidien LP Occlusive devices
US10039536B2 (en) 2012-11-16 2018-08-07 W. L. Gore & Associates, Inc. Implantable medical device deployment system
US9539022B2 (en) 2012-11-28 2017-01-10 Microvention, Inc. Matter conveyance system
EP2928558B1 (en) 2012-12-07 2017-09-06 Medtronic Inc. Minimally invasive implantable neurostimulation system
US10342546B2 (en) 2013-01-14 2019-07-09 Microvention, Inc. Occlusive device
US10716549B2 (en) 2013-03-05 2020-07-21 St. Jude Medical, Cardiology Division, Inc. Medical device for treating a target site
US10973523B2 (en) 2013-03-08 2021-04-13 Aga Medical Corporation Medical device for treating a target site
US9681861B2 (en) 2013-03-11 2017-06-20 St. Jude Medical, Cardiology Division, Inc. Percutaneous catheter directed collapsible medical closure device
US9539382B2 (en) 2013-03-12 2017-01-10 Medtronic, Inc. Stepped catheters with flow restrictors and infusion systems using the same
WO2014150824A1 (en) 2013-03-14 2014-09-25 Stryker Corporation Vaso-occlusive device delivery system
ES2879634T3 (es) 2013-03-14 2021-11-22 Stryker Corp Sistema de administración de dispositivo vasooclusivo
CN105228534B (zh) 2013-03-14 2018-03-30 斯瑞克公司 血管闭塞装置输送系统
CN105377184B (zh) 2013-03-15 2017-06-30 微仙美国有限公司 栓塞保护装置
CN105228688B (zh) * 2013-03-15 2019-02-19 伊瑟拉医疗公司 脉管治疗装置和方法
US9398966B2 (en) 2013-03-15 2016-07-26 Medtronic Vascular, Inc. Welded stent and stent delivery system
US10736758B2 (en) 2013-03-15 2020-08-11 Covidien Occlusive device
US9833252B2 (en) 2013-03-15 2017-12-05 Microvention, Inc. Multi-component obstruction removal system and method
WO2014174437A1 (en) 2013-04-22 2014-10-30 Sandvik Intellectual Property Ab Method for drug loading hydroxyapatite coated implant surfaces
US9445928B2 (en) 2013-05-30 2016-09-20 Medtronic Vascular, Inc. Delivery system having a single handed deployment handle for a retractable outer sheath
DE102013106031B4 (de) 2013-06-11 2015-07-02 Acandis Gmbh & Co. Kg Medizinisches Implantat und System mit einem derartigen Implantat
WO2017142874A2 (en) 2016-02-16 2017-08-24 Insera Therapeutics, Inc. Aspiration devices and anchored flow diverting devices
US9078658B2 (en) 2013-08-16 2015-07-14 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
US9955976B2 (en) 2013-08-16 2018-05-01 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
CA2918098A1 (en) * 2013-08-20 2015-02-26 Boston Scientific Scimed, Inc. Braided hemostasis shaft for improved torsional response
US10076399B2 (en) 2013-09-13 2018-09-18 Covidien Lp Endovascular device engagement
US9675782B2 (en) 2013-10-10 2017-06-13 Medtronic Vascular, Inc. Catheter pull wire actuation mechanism
US9795391B2 (en) 2013-10-25 2017-10-24 Medtronic Vascular, Inc. Tissue compression device with tension limiting strap retainer
WO2015073704A1 (en) 2013-11-13 2015-05-21 Covidien Lp Galvanically assisted attachment of medical devices to thrombus
EP3082660B1 (en) 2013-12-20 2020-01-22 Microvention, Inc. Device delivery system
JP6412137B2 (ja) 2013-12-20 2018-10-24 マイクロベンション インコーポレイテッドＭｉｃｒｏｖｅｎｔｉｏｎ， Ｉｎｃ． 吐液アダプタ
US11076860B2 (en) 2014-03-31 2021-08-03 DePuy Synthes Products, Inc. Aneurysm occlusion device
US11154302B2 (en) 2014-03-31 2021-10-26 DePuy Synthes Products, Inc. Aneurysm occlusion device
ES2684405T3 (es) 2014-04-08 2018-10-02 Stryker Corporation Sistema de suministro de implante
WO2015160721A1 (en) 2014-04-14 2015-10-22 Sequent Medical Inc. Devices for therapeutic vascular procedures
US9629635B2 (en) 2014-04-14 2017-04-25 Sequent Medical, Inc. Devices for therapeutic vascular procedures
WO2015166013A1 (en) 2014-04-30 2015-11-05 Cerus Endovascular Limited Occlusion device
US20170049596A1 (en) 2014-04-30 2017-02-23 Stryker Corporation Implant delivery system and method of use
EP3821818A3 (en) 2014-05-14 2021-07-21 President and Fellows of Harvard College Catheter device for transmitting and reflecting light
EP3148481A4 (en) 2014-05-28 2017-05-03 Stryker European Holdings I, LLC Vaso-occlusive devices and methods of use
US9060777B1 (en) 2014-05-28 2015-06-23 Tw Medical Technologies, Llc Vaso-occlusive devices and methods of use
US20150351775A1 (en) 2014-06-04 2015-12-10 Nfinium Vascular Technologies, Llc Low radial force vascular device and method of occlusion
BR102014014407A2 (pt) 2014-06-12 2016-04-19 Biocelere Agroindustrial Ltda cassete de expressão para transformar célula eucariótica, micro-organismo geneticamente modificado com eficiente consumo de xilose, processo para produção de biocombustíveis e bioquímicos e biocombustível e/ou bioquímico assim produzido
US8900304B1 (en) 2014-06-17 2014-12-02 Abdulrazzaq Alobaid Kyphoplasty cement encapsulation balloon
US9668898B2 (en) 2014-07-24 2017-06-06 Medtronic Vascular, Inc. Stent delivery system having dynamic deployment and methods of manufacturing same
US9770577B2 (en) 2014-09-15 2017-09-26 Medtronic Xomed, Inc. Pressure relief for a catheter balloon device
RU2020115524A (ru) 2014-09-17 2020-06-05 Метэктив Медикал, Инк. Устройство в виде расширяемого тела и способ его применения
US9579484B2 (en) 2014-09-19 2017-02-28 Medtronic Vascular, Inc. Sterile molded dispenser
CN104605909A (zh) 2014-12-30 2015-05-13 先健科技(深圳)有限公司 封堵器及其制作方法以及用于制作封堵器的编织网管
CA2972620C (en) * 2015-01-20 2023-08-01 Neurogami Medical, Inc. Micrograft for the treatment of intracranial aneurysms and method for use
US9692557B2 (en) 2015-02-04 2017-06-27 Stryker European Holdings I, Llc Apparatus and methods for administering treatment within a bodily duct of a patient
CA2976260C (en) 2015-02-25 2024-02-06 Galaxy Therapeutics, Llc System for and method of treating aneurysms
CN204683687U (zh) 2015-04-15 2015-10-07 中国人民解放军第二军医大学 一种颅内动脉瘤瘤颈重建装置
CN104958087B (zh) 2015-07-28 2018-09-25 杭州诺茂医疗科技有限公司 一种左心耳封堵器
US10307168B2 (en) 2015-08-07 2019-06-04 Terumo Corporation Complex coil and manufacturing techniques
US10154905B2 (en) 2015-08-07 2018-12-18 Medtronic Vascular, Inc. System and method for deflecting a delivery catheter
JP6735814B2 (ja) 2015-08-11 2020-08-05 テルモ株式会社 インプラント配送のためのシステムおよび方法
CN108156803B (zh) 2015-09-18 2021-05-04 泰尔茂株式会社 可推动的植入物传送系统
EP3349689B1 (en) 2015-09-18 2023-12-27 Microvention, Inc. Implant retention, detachment, and delivery system
EP3349670B1 (en) 2015-09-18 2020-09-09 Microvention, Inc. Releasable delivery system
WO2017049212A1 (en) 2015-09-18 2017-03-23 Microvention, Inc. Vessel prosthesis
EP3352689B1 (en) 2015-09-21 2018-12-26 Stryker Corporation Embolectomy devices
WO2017053271A1 (en) 2015-09-21 2017-03-30 Stryker Corporation Embolectomy devices
US10172632B2 (en) 2015-09-22 2019-01-08 Medtronic Vascular, Inc. Occlusion bypassing apparatus with a re-entry needle and a stabilization tube
US10314593B2 (en) 2015-09-23 2019-06-11 Covidien Lp Occlusive devices
US10478194B2 (en) 2015-09-23 2019-11-19 Covidien Lp Occlusive devices
US10327791B2 (en) 2015-10-07 2019-06-25 Medtronic Vascular, Inc. Occlusion bypassing apparatus with a re-entry needle and a distal stabilization balloon
US20170100143A1 (en) 2015-10-07 2017-04-13 Stryker Corporation Multiple barrel clot removal devices
US10786302B2 (en) 2015-10-09 2020-09-29 Medtronic, Inc. Method for closure and ablation of atrial appendage
US10271873B2 (en) 2015-10-26 2019-04-30 Medtronic Vascular, Inc. Sheathless guide catheter assembly
US20170147765A1 (en) 2015-11-19 2017-05-25 Penumbra, Inc. Systems and methods for treatment of stroke
US10631946B2 (en) 2015-11-30 2020-04-28 Penumbra, Inc. System for endoscopic intracranial procedures
WO2017100472A1 (en) 2015-12-09 2017-06-15 Medtronic Vascular Inc. Catheter with a lumen shaped as an identification symbol
US10500046B2 (en) 2015-12-14 2019-12-10 Medtronic, Inc. Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis
US10159568B2 (en) 2015-12-14 2018-12-25 Medtronic, Inc. Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis
WO2017117284A1 (en) 2015-12-30 2017-07-06 Stryker Corporation Embolic devices and methods of manufacturing same
US20170189033A1 (en) 2016-01-06 2017-07-06 Microvention, Inc. Occlusive Embolic Coil
US10070950B2 (en) 2016-02-09 2018-09-11 Medtronic Vascular, Inc. Endoluminal prosthetic assemblies, and associated systems and methods for percutaneous repair of a vascular tissue defect
CN109069796B (zh) 2016-02-10 2021-07-30 微仙美国有限公司 血管内治疗部位进入
WO2017139702A1 (en) 2016-02-10 2017-08-17 Microvention, Inc. Devices for vascular occlusion
US10188500B2 (en) 2016-02-12 2019-01-29 Medtronic Vascular, Inc. Stent graft with external scaffolding and method
US10952739B2 (en) 2016-03-11 2021-03-23 Sequent Medical, Inc. Systems and methods for delivery of stents and stent-like devices
JP6937327B2 (ja) 2016-03-17 2021-09-22 スワミナサン ジャヤラマン 解剖学的構造の閉塞
CN108883254B (zh) 2016-03-31 2022-03-29 美敦力瓦斯科尔勒公司 具有转向机构的可扩展导引器护套
US20170281331A1 (en) 2016-03-31 2017-10-05 Medtronic Vascular, Inc. Endoluminal prosthetic devices having fluid-absorbable compositions for repair of a vascular tissue defect
US10695542B2 (en) 2016-04-04 2020-06-30 Medtronic Vascular, Inc. Drug coated balloon
US10252024B2 (en) 2016-04-05 2019-04-09 Stryker Corporation Medical devices and methods of manufacturing same
US10441407B2 (en) 2016-04-12 2019-10-15 Medtronic Vascular, Inc. Gutter filling stent-graft and method
US9987122B2 (en) 2016-04-13 2018-06-05 Medtronic Vascular, Inc. Iliac branch device and method
US10010403B2 (en) 2016-04-18 2018-07-03 Medtronic Vascular, Inc. Stent-graft prosthesis and method of manufacture
US20170304097A1 (en) 2016-04-21 2017-10-26 Medtronic Vascular, Inc. Stent-graft delivery system having an inner shaft component with a loading pad or covering on a distal segment thereof for stent retention
US10940294B2 (en) 2016-04-25 2021-03-09 Medtronic Vascular, Inc. Balloon catheter including a drug delivery sheath
US10512478B2 (en) 2016-04-25 2019-12-24 Stryker Corporation Clot-engulfing mechanical thrombectomy apparatuses
US10517711B2 (en) 2016-04-25 2019-12-31 Medtronic Vascular, Inc. Dissection prosthesis system and method
EP3590446B1 (en) 2016-04-25 2021-01-06 Stryker Corporation Anti-jamming and macerating thrombectomy apparatuses
WO2017189591A1 (en) 2016-04-25 2017-11-02 Stryker Corporation Inverting mechanical thrombectomy apparatuses and methods of use in the vasculature
US10406011B2 (en) 2016-04-28 2019-09-10 Medtronic Vascular, Inc. Implantable medical device delivery system
US10191615B2 (en) 2016-04-28 2019-01-29 Medtronic Navigation, Inc. Method and apparatus for image-based navigation
US11147952B2 (en) 2016-04-28 2021-10-19 Medtronic Vascular, Inc. Drug coated inflatable balloon having a thermal dependent release layer
US10292844B2 (en) 2016-05-17 2019-05-21 Medtronic Vascular, Inc. Method for compressing a stented prosthesis
JP6803929B2 (ja) 2016-06-01 2020-12-23 マイクロベンション インコーポレイテッドＭｉｃｒｏｖｅｎｔｉｏｎ， Ｉｎｃ． 向上した補強バルーンカテーテル
ES2924974T3 (es) 2016-06-03 2022-10-13 Stryker Corp Aparatos de trombectomía de inversión
US20200000477A1 (en) 2016-08-03 2020-01-02 Henry Nita LLC Embolization Plug
WO2018051187A1 (en) 2016-09-14 2018-03-22 Medinol Ltd. Aneurysm closure device
JP7139346B2 (ja) 2017-02-23 2022-09-20 デピュイ・シンセス・プロダクツ・インコーポレイテッド 動脈瘤装置及び送達システム
US20180303531A1 (en) 2017-04-24 2018-10-25 Baxter International Inc. Single-handed applicator
US10952740B2 (en) 2017-05-25 2021-03-23 Terumo Corporation Adhesive occlusion systems
CN107374688A (zh) 2017-07-17 2017-11-24 湖南瑞康通科技发展有限公司 一种管腔内封堵装置
IL272716B2 (en) 2017-08-21 2023-09-01 Cerus Endovascular Ltd Install a block
US10806462B2 (en) 2017-12-21 2020-10-20 DePuy Synthes Products, Inc. Implantable medical device detachment system with split tube and cylindrical coupling
US10751065B2 (en) 2017-12-22 2020-08-25 DePuy Synthes Products, Inc. Aneurysm device and delivery system
US10716574B2 (en) 2017-12-22 2020-07-21 DePuy Synthes Products, Inc. Aneurysm device and delivery method
US11103252B2 (en) * 2018-01-23 2021-08-31 Swaminathan Jayaraman Device to treat vascular defect and method of making the same
US10905430B2 (en) * 2018-01-24 2021-02-02 DePuy Synthes Products, Inc. Aneurysm device and delivery system
US10806461B2 (en) 2018-04-27 2020-10-20 DePuy Synthes Products, Inc. Implantable medical device detachment system with split tube
US11596412B2 (en) * 2018-05-25 2023-03-07 DePuy Synthes Products, Inc. Aneurysm device and delivery system
US11058430B2 (en) * 2018-05-25 2021-07-13 DePuy Synthes Products, Inc. Aneurysm device and delivery system
US10939915B2 (en) 2018-05-31 2021-03-09 DePuy Synthes Products, Inc. Aneurysm device and delivery system
US10653425B1 (en) 2019-05-21 2020-05-19 DePuy Synthes Products, Inc. Layered braided aneurysm treatment device

Also Published As

Publication number Publication date
US20210169495A1 (en) 2021-06-10
JP2021087772A (ja) 2021-06-10
EP3831316A3 (en) 2021-10-13
EP3831316A2 (en) 2021-06-09
KR20210070916A (ko) 2021-06-15
US20230062395A1 (en) 2023-03-02
US11602350B2 (en) 2023-03-14

Similar Documents

Publication Publication Date Title
CN112914656A (zh) 具有高度柔性填充材料的囊内翻转编织物
US11376012B2 (en) Devices, systems, and methods for treatment of vascular defects
US11457926B2 (en) Implant having an intrasaccular section and intravascular section
US11337706B2 (en) Aneurysm treatment device
US11278292B2 (en) Inverting braided aneurysm treatment system and method
CN108433769B (zh) 闭塞装置
US11413046B2 (en) Layered braided aneurysm treatment device
CN110786907A (zh) 用于栓塞编织物的螺旋递送系统
US11607226B2 (en) Layered braided aneurysm treatment device with corrugations
US20200305885A1 (en) Aneurysm treatment device
US20220202425A1 (en) Semispherical braided aneurysm treatment system and method
US20220087681A1 (en) Inverting braided aneurysm implant with dome feature
JP2020189093A (ja) 層化編組動脈瘤処置デバイス
CN114366206A (zh) 翻转编织动脉瘤治疗系统和方法
WO2023175451A1 (en) Semispherical braided aneurysm treatment system and method

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20210608