CN1129118A - Compound notoginseng preparation - Google Patents
Compound notoginseng preparation Download PDFInfo
- Publication number
- CN1129118A CN1129118A CN 95101731 CN95101731A CN1129118A CN 1129118 A CN1129118 A CN 1129118A CN 95101731 CN95101731 CN 95101731 CN 95101731 A CN95101731 A CN 95101731A CN 1129118 A CN1129118 A CN 1129118A
- Authority
- CN
- China
- Prior art keywords
- extract
- preparation
- notoginseng
- aging
- radix notoginseng
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000180649 Panax notoginseng Species 0.000 title claims abstract description 22
- 235000003143 Panax notoginseng Nutrition 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 150000001875 compounds Chemical class 0.000 title claims abstract description 8
- 239000000284 extract Substances 0.000 claims abstract description 11
- PUQSUZTXKPLAPR-UJPOAAIJSA-N Gastrodin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(CO)C=C1 PUQSUZTXKPLAPR-UJPOAAIJSA-N 0.000 claims abstract description 9
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract description 3
- 229940124531 pharmaceutical excipient Drugs 0.000 claims abstract description 3
- 239000000203 mixture Substances 0.000 claims description 12
- 210000000582 semen Anatomy 0.000 claims description 10
- 241000218628 Ginkgo Species 0.000 claims description 8
- 235000011201 Ginkgo Nutrition 0.000 claims description 8
- 235000008100 Ginkgo biloba Nutrition 0.000 claims description 8
- 239000000469 ethanolic extract Substances 0.000 claims description 6
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 claims description 4
- 229930003944 flavone Natural products 0.000 claims description 4
- 150000002212 flavone derivatives Chemical class 0.000 claims description 4
- 235000011949 flavones Nutrition 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 4
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 claims description 4
- -1 terpene lactones Chemical class 0.000 claims description 2
- 235000007586 terpenes Nutrition 0.000 claims description 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract description 8
- 208000026106 cerebrovascular disease Diseases 0.000 abstract description 7
- 230000032683 aging Effects 0.000 abstract description 6
- 239000003814 drug Substances 0.000 abstract description 6
- 230000002526 effect on cardiovascular system Effects 0.000 abstract description 6
- DJSISFGPUUYILV-UHFFFAOYSA-N UNPD161792 Natural products O1C(C(O)=O)C(O)C(O)C(O)C1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC(O)=CC=1)O2 DJSISFGPUUYILV-UHFFFAOYSA-N 0.000 abstract description 3
- 210000004556 brain Anatomy 0.000 abstract description 3
- DJSISFGPUUYILV-ZFORQUDYSA-N scutellarin Chemical group O1[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC(O)=CC=1)O2 DJSISFGPUUYILV-ZFORQUDYSA-N 0.000 abstract description 3
- 230000000295 complement effect Effects 0.000 abstract description 2
- 239000002552 dosage form Substances 0.000 abstract description 2
- PUQSUZTXKPLAPR-KSSYENDESA-N 4-(beta-D-Glucopyranosyloxy) benzyl alcohol Natural products O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)c1ccc(CO)cc1 PUQSUZTXKPLAPR-KSSYENDESA-N 0.000 abstract 1
- 239000009429 Ginkgo biloba extract Substances 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 229930193974 gastrodin Natural products 0.000 abstract 1
- 229940068052 ginkgo biloba extract Drugs 0.000 abstract 1
- 235000020686 ginkgo biloba extract Nutrition 0.000 abstract 1
- PUQSUZTXKPLAPR-NZEXEKPDSA-N helicidol Natural products O([C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](CO)O1)c1ccc(CO)cc1 PUQSUZTXKPLAPR-NZEXEKPDSA-N 0.000 abstract 1
- 230000036737 immune function Effects 0.000 abstract 1
- 238000005728 strengthening Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 description 6
- 230000002107 myocardial effect Effects 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 2
- 241000218176 Corydalis Species 0.000 description 2
- 241000628997 Flos Species 0.000 description 2
- 239000009636 Huang Qi Substances 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000000287 crude extract Substances 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 150000002338 glycosides Chemical class 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000036284 oxygen consumption Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 241000717739 Boswellia sacra Species 0.000 description 1
- 206010008132 Cerebral thrombosis Diseases 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 241000132521 Erigeron Species 0.000 description 1
- 239000004863 Frankincense Substances 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 235000015511 Liquidambar orientalis Nutrition 0.000 description 1
- 241001057584 Myrrha Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 239000004870 Styrax Substances 0.000 description 1
- 244000028419 Styrax benzoin Species 0.000 description 1
- 235000000126 Styrax benzoin Nutrition 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N p-menthan-3-ol Chemical compound CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 230000037081 physical activity Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a notoginseng compound preparation which mainly uses notoginseng and is used for curing angiocardiopathy and cerebrovascular disease. The preparation of the invention comprises the following components (weight percentage): 30-90% of pseudo-ginseng extract, X20-70% (one or the combination of any two or three of X ═ breviscapine extract, ginkgo biloba extract and gastrodin), and appropriate pharmaceutical excipients to prepare a pharmaceutically acceptable preparation. The medicine of the invention is mainly used for treating cardiovascular and cerebrovascular diseases and resisting aging, has clear and primary whole formula, proper matching and complementary mutual promotion, can improve the human body, prevent the brain aging and enhance the immunologic function, thereby playing the roles of delaying aging and strengthening the body. Can be made into various dosage forms, and is convenient for use.
Description
The present invention relates to notoginseng preparation based on the treatment cardiovascular and cerebrovascular disease of Radix Notoginseng.
Chinese patent application CN1030183 (application number 87104599) discloses " a kind of manufacture method of preventing and treating the coronary heart disease medicine for external use ", be with tens of flavor Chinese medicine dryings, pulverize, sieve, mix, it is characterized in that: (1) is with a certain amount of Radix Scrophulariae, Radix Angelicae Sinensis, Semen Cassiae, Yin Jiye, Radix Curcumae, Rhizoma Corydalis, Flos Carthami, Myrrha, Olibanum, Rhizoma Acori Graminei, the flower bean, Ramulus Cinnamomi, Bulbus Allii Macrostemonis, Fructus Trichosanthis, Radix Codonopsis, the Radix Astragali, Lignum Dalbergiae Odoriferae, Polygonm multiflorum Thunb Teng is totally 18 flavor Chinese medicines, descended dry 5 hours at about 50 ℃ Celsius together, again in sombre dry place cold 5 hours, pulverized 80 mesh sieves then, waste stays powder; (2) get a certain amount of Borneolum Syntheticum and Radix Notoginseng powder and smash the grind up face jointly; (3) with above-mentioned two kinds of powder (or powder face) mixing and stirring.Chinese patent application CN1087272 (application number 92114065) discloses a kind of " a kind of Chinese powder medicine capsule that is used for the treatment of chronic ischemic heart disease ", it is characterized in that Chinese powder medicine prescription and percentage by weight in the capsule are: Radix Ginseng 2-5%, Radix Astragali 22-26%, Radix Notoginseng 1-3%, Flos Carthami 10-14%, Rhizoma Corydalis 10-14%, red energy 22-26%, Lignum Santali Albi 6-10%, Semen Alpiniae Katsumadai 10-14%, Styrax 0.6-1.0%, Borneolum Syntheticum 0.06-0.10%, Mentholum 0.02-0.06%.
Purpose of the present invention aims to provide a kind of compound formulation of notoginseng for the treatment of cardiovascular and cerebrovascular disease.
Compound formulation of notoginseng of the present invention is formed (percentage by weight) by following composition: Radix Notoginseng extract 30-90%, X20-70% (X=Herba Erigerontis extract, Semen Ginkgo extrac, the combination of a kind of in the gastrodine or wherein any two kinds, three kinds), be equipped with proper pharmaceutical excipients and make acceptable preparation.
In the composition of the present invention, Radix Notoginseng extract is the ethanol extract of Radix Notoginseng, can be crude extract, can also be extract, contains arasaponin 50-95%, Herba Erigerontis extract is the Herba Erigerontis ethanol extract, contain flavone 40-95%, Semen Ginkgo extrac is the Semen Ginkgo ethanol extract, contains flavone 10-35%, terpene lactones 1-10%, gastrodine can be with the commercially available gastrodine that meets medicinal standard.
In the above-mentioned composition, Radix Notoginseng is at blood system, cardiovascular system, nervous system, immunity metabolic system and antiinflammatory, defying age, there is the important physical activity aspects such as antitumor, and blood circulation promoting and blood stasis dispelling reduces myocardial oxygen consumption, improve the brain oxygen-supplying amount, promote cerebral nerve to grow and the SOD activity, Herba Erigerontis and Semen Ginkgo extrac have activity to blood vessel, also can remove free radical, improve myocardial oxygen delivery and hemorheology, gastrodine has the calmness of calming the nerves, and studies show that in recent years gastrodine can reduce myocardial oxygen consumption, increases the myocardial nutrition blood volume, increase blood flow inertia in the arteries, improve vascular compliance.
Drug main of the present invention will be treated cardiovascular and cerebrovascular disease and defying age, make a distinction between the important and the lesser one in full side, tie in, complementary short mutually, making perfect square is effective good recipe of cardiovascular disease, can improve human body and prevent aging of brain, raise immunity, thereby the effect of playing slow down aging and improving the body and culature improves survival rate and life quality.Can be made into multiple dosage form, easy to use.
Embodiment:
1, gets Radix Notoginseng total arasaponins (elaboration) 100 * 10,000mg, breviscapine soluble salt 50 * 10,000mg, add Purified Water to 2 ten thousand ml, dissolving is filtered, for 2ml/ props up, sterilization, promptly getting specification is that 2ml/ props up, and contains arasaponin 100mg, 10,000 of the compound recipe Radix Notoginseng fleabane injections of breviscapine 50mg can be used for the apoplectic hemiplegia that cardiovascular and cerebrovascular disease and cerebral thrombosis cause.
2, get the thick glycoside 100mg of Radix Notoginseng * 10,000 (containing Saponin 50-90%), Semen Ginkgo extrac 60mg * 10,000, gastrodine 25mg * 10,000, soluble starch 65mg * 10,000.
Medicine-feeding grinds well, and sieves, granulates, is distributed into 10,000, promptly gets compound recipe three silver medal cellulose capsules, can be used for senile cardiovascular disease and prevents old diseases such as aging, alzheimer disease.
3, get the thick glycoside 60mg of Radix Notoginseng * 10,000, Herba Erigerontis crude extract 50mg * 10,000, gastrodine 50mg * 10,000, Mel is an amount of, adds water 100,000 ml, by oral liquid process, be distributed into 10,000 of the oral liquids that 10ml/ props up, can be used for cardiovascular and cerebrovascular disease and mutation, prevent that cancer from shifting.
Claims (4)
1, a kind of compound formulation of notoginseng, it is characterized in that forming (percentage by weight): Radix Notoginseng extract 30-90% by following composition, X20-70% (X=Herba Erigerontis extract, Semen Ginkgo extrac, the combination of a kind of in the gastrodine or wherein any two kinds, three kinds), be equipped with proper pharmaceutical excipients and make acceptable preparation.
2, according to the described preparation of claim 1, it is characterized in that Radix Notoginseng extract is the ethanol extract of Radix Notoginseng in the described composition, contain arasaponin 50-95%.
3, according to the described preparation of claim 1, it is characterized in that Herba Erigerontis extract is the Herba Erigerontis ethanol extract in the described composition, contain flavone 40-95%.
4, according to the described preparation of claim 1, it is characterized in that Semen Ginkgo extrac is the Semen Ginkgo ethanol extract in the described composition, contain flavone 10-35%, terpene lactones 1-10%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95101731A CN1058615C (en) | 1995-02-15 | 1995-02-15 | Compound notoginseng preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95101731A CN1058615C (en) | 1995-02-15 | 1995-02-15 | Compound notoginseng preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1129118A true CN1129118A (en) | 1996-08-21 |
| CN1058615C CN1058615C (en) | 2000-11-22 |
Family
ID=5074066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95101731A Expired - Lifetime CN1058615C (en) | 1995-02-15 | 1995-02-15 | Compound notoginseng preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1058615C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1064258C (en) * | 1998-03-17 | 2001-04-11 | 昆明制药股份有限公司 | Soft capsule of notoginseng extract and its preparing process |
| CN100417387C (en) * | 2004-06-17 | 2008-09-10 | 秦引林 | Compound injection formulation compose dof borneol and pseudo-ginseng total saponin and its preparing method |
| CN101773179A (en) * | 2010-03-19 | 2010-07-14 | 马伟光 | Health-caring tea for preventing cardiovascular and cerebrovascular diseases and preparation method thereof |
| CN102940657A (en) * | 2012-10-31 | 2013-02-27 | 成都医路康医学技术服务有限公司 | Medicine composition for treating cardia-cerebrovascular diseases |
| CN105535057A (en) * | 2016-01-09 | 2016-05-04 | 王升云 | Composition capable of assisting in reduction of blood fat and preparing method, preparation and application thereof |
| CN111569008A (en) * | 2020-05-09 | 2020-08-25 | 昆明医科大学 | A pharmaceutical composition for treating neurodegenerative diseases |
| CN112494607A (en) * | 2020-12-09 | 2021-03-16 | 云南中医药大学 | Pharmaceutical composition for preventing and treating cerebral apoplexy and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055836C (en) * | 1993-12-01 | 2000-08-30 | 贺明哲 | Fresh-juice Tianmami (gastrodia tuber sweet) health care food and making method |
-
1995
- 1995-02-15 CN CN95101731A patent/CN1058615C/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1064258C (en) * | 1998-03-17 | 2001-04-11 | 昆明制药股份有限公司 | Soft capsule of notoginseng extract and its preparing process |
| CN100417387C (en) * | 2004-06-17 | 2008-09-10 | 秦引林 | Compound injection formulation compose dof borneol and pseudo-ginseng total saponin and its preparing method |
| CN101773179A (en) * | 2010-03-19 | 2010-07-14 | 马伟光 | Health-caring tea for preventing cardiovascular and cerebrovascular diseases and preparation method thereof |
| CN101773179B (en) * | 2010-03-19 | 2012-07-18 | 马伟光 | Health-caring tea for preventing cardiovascular and cerebrovascular diseases and preparation method thereof |
| CN102940657A (en) * | 2012-10-31 | 2013-02-27 | 成都医路康医学技术服务有限公司 | Medicine composition for treating cardia-cerebrovascular diseases |
| CN105535057A (en) * | 2016-01-09 | 2016-05-04 | 王升云 | Composition capable of assisting in reduction of blood fat and preparing method, preparation and application thereof |
| CN111569008A (en) * | 2020-05-09 | 2020-08-25 | 昆明医科大学 | A pharmaceutical composition for treating neurodegenerative diseases |
| CN112494607A (en) * | 2020-12-09 | 2021-03-16 | 云南中医药大学 | Pharmaceutical composition for preventing and treating cerebral apoplexy and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1058615C (en) | 2000-11-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1931261B (en) | Blood pressure and blood lipid lowering capsule and its preparation process | |
| CN101357136A (en) | Composition of traditional Chinese medicine effective constituent for preventing and treating diseased associated with cerebral ischemia injury | |
| CN102293927B (en) | Compound Chinese medicinal preparation with antifatigue and antioxidation effects, and preparation method thereof | |
| CN1058615C (en) | Compound notoginseng preparation | |
| CN101732395B (en) | Medicine or health-care food composition with function of regulating immunity, preparation method and application thereof | |
| CN1263503C (en) | 'Changyuan' capsule and preparing techniue | |
| CN111297965A (en) | Traditional Chinese medicine composition for treating chronic nephritis | |
| CN1827136A (en) | Compound Chinese medicinal preparation for treating male sterility | |
| CN102552708A (en) | Medicinal composition for calming liver wind | |
| CN105287990A (en) | Traditional Chinese medicinal preparation for preventing and treating senile dementia and preparation method of traditional Chinese medicinal preparation | |
| CN115487239A (en) | Pharmaceutical composition for treating insomnia with anxiety and depression and preparation method thereof | |
| CN104922295A (en) | Blood-nourishing and blood-enriching traditional Chinese medicine composition | |
| CN1369289A (en) | Chinese medicine for treating cardiovascular and cerebrovascular diseases and its preparing process | |
| CN101623474B (en) | Preparation method of Shengui antler oral solid preparation | |
| CN100479837C (en) | Weinakang for treating ischemic cerebrovascular disease and senile dementia and preparation method thereof | |
| CN106360716A (en) | Traditional Chinese medicinal composition for improving body immunity and sleep, and preparation method thereof | |
| CN101559124B (en) | Compound preparation for treating liver cancer and preparation method thereof | |
| CN1060663C (en) | Compound Tibet capillary artemisia patent medicine | |
| CN101411778A (en) | Chinese medicine effective component composition and method for preparing the same | |
| CN117159658B (en) | A Chinese medicinal composition for preventing, relieving or treating intractable insomnia, and its preparation method | |
| CN100493528C (en) | Medicine granule and its preparing method | |
| CN101385814A (en) | Medicine for treating the coronary heart disease and preparation method thereof | |
| CN1935183A (en) | Chinese medicine compound preparation and its preparing method | |
| CN105343688A (en) | Medicine composition for treating myocardial infarction and application thereof | |
| CN1488382A (en) | Health-care medicine for preventing and curing cardio-cerebrovascular diseae |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Applicant after: Kunming Pharmaceutical Co., Ltd. Applicant before: Kunming Pharmaceutical Factory |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: KUNMING PHARMACEUTICAL FACTORY TO: KUNMING MEDICINE STOCK CO., LTD. |
|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: KUNMING MEDICINE GROUP STOCK CO., LTD. Free format text: FORMER NAME OR ADDRESS: KUNMING MEDICINE STOCK CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Patentee after: Kunming Pharmaceutical Group Co., Ltd Patentee before: Kunming Pharmaceutical Co., Ltd. |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20150215 Granted publication date: 20001122 |