CN1488382A - Health-care medicine for preventing and curing cardio-cerebrovascular diseae - Google Patents
Health-care medicine for preventing and curing cardio-cerebrovascular diseae Download PDFInfo
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- CN1488382A CN1488382A CNA031390013A CN03139001A CN1488382A CN 1488382 A CN1488382 A CN 1488382A CN A031390013 A CNA031390013 A CN A031390013A CN 03139001 A CN03139001 A CN 03139001A CN 1488382 A CN1488382 A CN 1488382A
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Abstract
The invention is a health drug to cure cardiovascular and cerebrovascular diseases. Its drug components (weight share): gingkgo leaf extract 1-30, and Salvia miltiorrhiza extract 1-60; take the two extracts according to the formula to mix and crush into 80-100 eye particles, to make into the Chinese medicinal preparation, able to any drug form. It has very good curative effect on prevention and cure of cardiovascular and cerebrovascular diseases.
Description
Affiliated technical field
The present invention relates to the health medicine of a kind of prevention and treatment cardiovascular and cerebrovascular disease, particularly a kind of is the Chinese medicine preparation of main effective ingredient by Folium Ginkgo and Radix Salviae Miltiorrhizae extract.
Background technology
Cardiovascular disease is a kind of commonly encountered diseases and frequently-occurring disease, has data to show, 10% middle-aged and elderly people has cardiovascular disease in various degree, and it is one of principal element of the rate of causing death.Therefore, research prevention and treatment treating cardiovascular disease medicine become the task of top priority.In recent years, Chinese medicine has been obtained certain progress having carried out series of experiment research and clinical application research aspect this disease of control, has shown the advantage of Chinese medicine.
Ginkgetin and bilobalide in the Folium Ginkgo extract have dilating effect to cardiovascular and cerebrovascular vessel, are used to prevent and treat cardiovascular and cerebrovascular disease, have important effect.
The main chemical compositions of Radix Salviae Miltiorrhizae has TANSHINONES, and it has the oxygen-derived free radicals of removing, regulates calcium stable, protective wire plastochondria, improves energy metabolism, improves significantly for the ischemic damage and reperfusion damage tool.Interior regulating action and this effect that the while Radix Salviae Miltiorrhizae is brought into play immunne response by the effect of the pair cell factor, antibody and immune complex, immunocyte have the amphicheirality.
More than two kinds of effects that medicine all has the cardiovascular and cerebrovascular vessel of preventing and treating, but also do not have use in conjunction, influenced the effect of control cardiovascular and cerebrovascular disease.
Summary of the invention
Purpose of the present invention is exactly at the deficiencies in the prior art, and propose a kind of with suitable proportioning with Folium Ginkgo extract and Radix Salviae Miltiorrhizae drug regimen, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease promptly is provided, make its control cardiovascular and cerebrovascular disease aspect better effects if.
Solution of the present invention is to be based upon Chinese medicine on the pathogenetic basis that studies for a long period of time of cardiovascular and cerebrovascular disease, achieve with reference to modern pharmacological research, from plant class Chinese herbal medicine, filter out the effective two kinds of drug regimens of control cardiovascular and cerebrovascular disease, the control cardiovascular and cerebrovascular disease has been obtained better curative effect.
Cheese has dilating effect to arteries in ginkgetin in the Folium Ginkgo extract and the Semen Ginkgo, is used to prevent and treat cardiovascular disease, has important effect.
The main chemical compositions of Radix Salviae Miltiorrhizae has TANSHINONES, and it has the oxygen-derived free radicals of removing, regulates calcium stable, protective wire plastochondria, improves energy metabolism, improves significantly for the ischemic damage and reperfusion damage tool.Interior regulating action and this effect that the while Radix Salviae Miltiorrhizae is brought into play immunne response by the effect of the pair cell factor, antibody and immune complex, immunocyte have the amphicheirality.
Technical scheme of the present invention is: the health medicine of this kind control cardiovascular and cerebrovascular disease, it is characterized in that forming (weight portion) by following medicine, Folium Ginkgo extract accounts for 1-30, Radix Salviae Miltiorrhizae extract accounts for 1-60, get Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, mixed powder is made Chinese medicine preparation after being broken to 80-100 order granularity.
Described Chinese medicine preparation is the above any dosage form of Chinese materia medica.Can make capsule preparations, tablet, electuary, oral liquid formulations, soft capsule preparation etc.
The combination of above medicine is united and is played a role, and has extraordinary curative effect for the control cardiovascular and cerebrovascular disease, and than single medicine good effect, effect is fast.This medicine dropped into clinical trial in 2000, and patient's popular welcome now discloses following case and describes:
Example 1. treatment myocardial infarctions 180 examples, 2 months courses of treatment, produce effects 80 examples as a result, 82 examples that take a turn for the better, invalid 18 examples, total effective rate 90%.
Example 2. treatment coronary heart disease 60 examples are cured 28 examples, 22 examples that take a turn for the better, invalid 10 examples, 83.3%.
Example 3. treatment hyperlipidemia 120 examples, produce effects 70 examples, effective 26 examples, invalid 24 examples, total effective rate 80%.
Example 4. treatment cerebral infarction animal experiments, the Wistar rat is selected in experiment for use, causes the animal brain cerebral infarction models by the Tamura method, animal is divided into test group and matched group, every group 20, test group is irritated stomach with this medicine, and matched group is irritated stomach with nimodipine, be administered once in 24 hours at interval, carry out behavioristics then and check and pathological examination that test group brain pathological lesion, behavior disorder have clear and definite improvement and therapeutical effect as a result, make good use of difference highly significant (P＜0.01) than matched group.
The clinical experiments of example 5. treatment cerebral infarction, cerebral infarction patient 60 examples, produce effects 20 examples as a result, effective 26 examples, invalid 14 examples, total effective rate 76.6%.
The specific embodiment
Example one: the health medicine of this kind control cardiovascular and cerebrovascular disease, form (weight portion) by following medicine: Folium Ginkgo extract accounts for 1, and Radix Salviae Miltiorrhizae extract accounts for 60, get Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, after mixed powder is broken to 80-100 order granularity, pelletize, encapsulated, make capsule preparations.Every heavy 500mg of this product, day clothes 3 times, each 1.
Example two: the health medicine of this kind control cardiovascular and cerebrovascular disease, form (weight portion) by following medicine: Folium Ginkgo extract accounts for 30, and Radix Salviae Miltiorrhizae extract accounts for 1, get Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, after mixed powder is broken to 80-100 order granularity, pelletize, tabletting is made tablet formulation.Every heavy 500mg of this product, day clothes 3 times, each 1.
Example three: the health medicine of this kind control cardiovascular and cerebrovascular disease, form (weight portion) by following medicine: Folium Ginkgo extract accounts for 15, and Radix Salviae Miltiorrhizae extract accounts for 30, gets Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, mixed powder is made the Chinese medicine electuary after being broken to 80-100 order granularity.The heavy 1g of the every bag of this product, day clothes 2 times, each 1 bag.
Example four: the health medicine of this kind control cardiovascular and cerebrovascular disease, form (weight portion) by following medicine: Folium Ginkgo extract accounts for 20, Radix Salviae Miltiorrhizae extract accounts for 40, get Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, after mixed powder is broken to 80-100 order granularity, with the sterilized water dissolving, oral liquid formulations is made in bottling.
Example five: the health medicine of this kind control cardiovascular and cerebrovascular disease, form (weight portion) by following medicine: Folium Ginkgo extract accounts for 10, Radix Salviae Miltiorrhizae extract accounts for 20, get Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, after mixed powder is broken to 80-100 order granularity, with the sterilized water dissolving, oral liquid formulations is made in bottling.Every bottle of 10ml of this product, day clothes 1 time, each 1 bottle.
Claims (7)
1, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease is characterized in that forming (weight portion) by following medicine, and Folium Ginkgo extract accounts for 1-30, Radix Salviae Miltiorrhizae extract accounts for 1-60, get Folium Ginkgo extract, Radix Salviae Miltiorrhizae extract by prescription, mixed powder is made Chinese medicine preparation after being broken to 80-100 order granularity.
2, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease according to claim 1 is characterized in that described Chinese medicine preparation is the above any dosage form of Chinese materia medica.
3, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease according to claim 2 is characterized in that described Chinese medicine preparation is a capsule preparations.
4, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease according to claim 2 is characterized in that described Chinese medicine preparation is a tablet.
5, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease according to claim 2 is characterized in that described Chinese medicine preparation is an electuary.
6, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease according to claim 2 is characterized in that described Chinese medicine preparation is an oral liquid formulations.
7, a kind of health medicine of preventing and treating cardiovascular and cerebrovascular disease according to claim 2 is characterized in that described Chinese medicine preparation is a soft capsule preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031390013A CN1488382A (en) | 2003-08-12 | 2003-08-12 | Health-care medicine for preventing and curing cardio-cerebrovascular diseae |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CNA031390013A CN1488382A (en) | 2003-08-12 | 2003-08-12 | Health-care medicine for preventing and curing cardio-cerebrovascular diseae |
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| CN1488382A true CN1488382A (en) | 2004-04-14 |
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| CNA031390013A Pending CN1488382A (en) | 2003-08-12 | 2003-08-12 | Health-care medicine for preventing and curing cardio-cerebrovascular diseae |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101274013B (en) * | 2007-03-27 | 2011-06-08 | 高海 | Prescription medicine for curing senile dementia and preparation |
| CN101156893B (en) * | 2005-02-07 | 2012-02-01 | 贵阳云岩西创药物科技开发有限公司 | Detection method of apricot red injection |
| CN102670978A (en) * | 2012-06-06 | 2012-09-19 | 张旺凡 | Polygonatum compound granule and preparing method thereof |
| CN108671074A (en) * | 2018-07-23 | 2018-10-19 | 北京瑞草科技有限公司 | Prevent and/or treat the ginkgo leaf matrimony vine compound oral liquid and preparation method thereof of cardiovascular and cerebrovascular disease |
-
2003
- 2003-08-12 CN CNA031390013A patent/CN1488382A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101156893B (en) * | 2005-02-07 | 2012-02-01 | 贵阳云岩西创药物科技开发有限公司 | Detection method of apricot red injection |
| CN101274013B (en) * | 2007-03-27 | 2011-06-08 | 高海 | Prescription medicine for curing senile dementia and preparation |
| CN102670978A (en) * | 2012-06-06 | 2012-09-19 | 张旺凡 | Polygonatum compound granule and preparing method thereof |
| CN102670978B (en) * | 2012-06-06 | 2017-12-19 | 张旺凡 | A kind of polygonatum compound granule and preparation method thereof |
| CN108671074A (en) * | 2018-07-23 | 2018-10-19 | 北京瑞草科技有限公司 | Prevent and/or treat the ginkgo leaf matrimony vine compound oral liquid and preparation method thereof of cardiovascular and cerebrovascular disease |
| CN108671074B (en) * | 2018-07-23 | 2022-03-08 | 北京瑞草科技有限公司 | Ginkgo leaf and wolfberry compound oral liquid for preventing and/or treating cardiovascular and cerebrovascular diseases and preparation method thereof |
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