CN1058615C - Compounded preparation of notoginseng - Google Patents
Compounded preparation of notoginseng Download PDFInfo
- Publication number
- CN1058615C CN1058615C CN95101731A CN95101731A CN1058615C CN 1058615 C CN1058615 C CN 1058615C CN 95101731 A CN95101731 A CN 95101731A CN 95101731 A CN95101731 A CN 95101731A CN 1058615 C CN1058615 C CN 1058615C
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- CN
- China
- Prior art keywords
- extract
- radix notoginseng
- present
- preparation
- notoginseng
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- Expired - Lifetime
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Abstract
The present invention relates to a radix notoginseng compound preparation which uses as radix notoginseng mainly and is used for treating cardiovascular and cerebrovascular diseases. The preparation of the present invention is composed of the components with the weight percent of 30 to 90% of radix notoginseng extract, 20 to 70% of X (X is one kind or the combination of any two kinds or any three kinds in breviscpini extract, gingko extract and gastrodin, and a medicinal acceptable preparation can be prepared by adding appropriate medicinal auxiliary materials. The medicine of the present invention mainly treats cardiovascular and cerebrovascular diseases and preventing caducity and has the advantages of clear whole level, appropriate addition and mutual promotion, bodies can be improved, brains can be prevented from aging, an immune function can be enhanced, and thereby, the functions of caducity delay and body building are performed. The present invention can be prepared into a plurality of dosage forms and can be used conveniently.
Description
The present invention relates to notoginseng preparation based on the treatment cardiovascular and cerebrovascular disease of Radix Notoginseng.
Chinese patent application CN1030183 (application number 87104599) discloses " a kind of manufacture method of preventing and treating the coronary heart disease medicine for external use ", be with tens of flavor Chinese medicine dryings, pulverize, sieve, mix, it is characterized in that: (1) is with a certain amount of Radix Scrophulariae, Radix Angelicae Sinensis, Semen Cassiae, Yin Jiye, Radix Curcumae, Rhizoma Corydalis, Flos Carthami, Myrrha, Olibanum, Rhizoma Acori Graminei, the flower bean, Ramulus Cinnamomi, Bulbus Allii Macrostemonis, Fructus Trichosanthis, Radix Codonopsis, the Radix Astragali, Lignum Dalbergiae Odoriferae, Polygonm multiflorum Thunb Teng is totally 18 flavor Chinese medicines, descended dry 5 hours at about 50 ℃ Celsius together, again in sombre dry place cold 5 hours, pulverized 80 mesh sieves then, waste stays powder; (2) get a certain amount of Borneolum Syntheticum and Radix Notoginseng powder and smash the grind up face jointly; (3) with above-mentioned two kinds of powder (or powder face) mixing and stirring.Chinese patent application CN1087272 (application number 92114065) discloses a kind of " a kind of Chinese powder medicine capsule that is used for the treatment of chronic ischemic heart disease ", it is characterized in that Chinese powder medicine prescription and the percentage by weight in the capsule is; Radix Ginseng 2-5%, Radix Astragali 22-26%, Radix Notoginseng 1-3%, Flos Carthami 10-14%, Rhizoma Corydalis 10-14%, red energy 22-26%, Lignum Santali Albi 6-10%, Semen Alpiniae Katsumadai 10-14%, Styrax 0.6-1.0%, Borneolum Syntheticum 0.06-0.10%, Mentholum 0.02-0.06%.
Purpose of the present invention aims to provide a kind of compound formulation of notoginseng for the treatment of cardiovascular and cerebrovascular disease.
Compound formulation of notoginseng of the present invention is formed (percentage by weight) by following composition: Radix Notoginseng extract 30-80%, X 20-70% (X=Herba Erigerontis extract, Semen Ginkgo extrac, the combination of a kind of in the gastrodine or wherein any two kinds, three kinds), be equipped with proper pharmaceutical excipients and make acceptable preparation.
In the composition of the present invention, Radix Notoginseng extract is the ethanol extract of Radix Notoginseng, can be crude extract, can also be extract, contains arasaponin 50-95%, Herba Erigerontis extract is the Herba Erigerontis ethanol extract, contain flavone 40-95%, Semen Ginkgo extrac is the Semen Ginkgo ethanol extract, contains flavone 10-35%, terpene lactones 1-10%, gastrodine can be with the commercially available gastrodine that meets medicinal standard.
In the above-mentioned composition, Radix Notoginseng is at blood system, cardiovascular system, nervous system, immunity metabolic system and antiinflammatory, defying age, there is the important physical activity aspects such as antitumor, and blood circulation promoting and blood stasis dispelling reduces myocardial oxygen consumption, improve the brain oxygen-supplying amount, promote cerebral nerve to grow and the SOD activity, Herba Erigerontis and Semen Ginkgo extrac have activity to blood vessel, also can remove free radical, improve myocardial oxygen delivery and hemorheology, gastrodine has the calmness of calming the nerves, and studies show that in recent years gastrodine can reduce myocardial oxygen consumption, increases the myocardial nutrition blood volume, increase blood flow inertia in the arteries, improve vascular compliance.
Drug main of the present invention will be treated cardiovascular and cerebrovascular disease and defying age, make a distinction between the important and the lesser one in full side, tie in, complementary short mutually, making perfect square is effective good recipe of cardiovascular disease, can improve human body and prevent aging of brain, raise immunity, thereby the effect of playing slow down aging and improving the body and culature improves survival rate and life quality.Can be made into multiple dosage form, easy to use.
Embodiment:
1, gets Radix Notoginseng total arasaponins (elaboration) 100 * 10,000mg, breviscapine soluble salt 50 * 10,000mg, add Purified Water to 2 ten thousand ml, dissolving is filtered, for 2ml/ props up, sterilization, promptly getting specification is that 2ml/ props up, and contains arasaponin 100mg, 10,000 of the compound recipe Radix Notoginseng fleabane injections of breviscapine 50mg can be used for the apoplectic hemiplegia that cardiovascular and cerebrovascular disease and cerebral thrombosis cause.
2, get the thick glycoside 100mg of Radix Notoginseng * 10,000 (containing Saponin 50-90%), Semen Ginkgo extrac 60mg * 10,000, gastrodine 25mg * 10,000, soluble starch 65mg * 10,000.
Medicine-feeding grinds well, and sieves, granulates, is distributed into 10,000, promptly gets compound recipe three silver medal cellulose capsules, can be used for senile cardiovascular disease and prevents old diseases such as aging, alzheimer disease.
3, get the thick glycoside 60mg of Radix Notoginseng * 10,000, Herba Erigerontis crude extract 50mg * 10,000, gastrodine 50mg * 10,000, Mel is an amount of, adds water 100,000 ml, by oral liquid process, be distributed into 10,000 of the oral liquids that 10ml/ props up, can be used for cardiovascular and cerebrovascular disease and mutation, prevent that cancer from shifting.
Claims (4)
1, a kind of compound formulation of notoginseng is characterized in that being made up of following composition: Radix Notoginseng extract 30-80%, a kind of or two kinds of 20-70% in Herba Erigerontis extract, the Semen Ginkgo extrac are equipped with proper pharmaceutical excipients and make acceptable preparation.
2, according to the described preparation of claim 1, it is characterized in that Radix Notoginseng extract is the ethanol extract of Radix Notoginseng in the described composition, contain arasaponin 50-95%.
3, according to the described preparation of claim 1, it is characterized in that the small cup flower extract is the Herba Erigerontis ethanol extract in the described composition, contain flavone 40-95%.
4, according to the described preparation of claim 1, it is characterized in that Semen Ginkgo extrac is the Semen Ginkgo ethanol extract in the described composition, contain flavone 10-35%, terpene lactones 1-10%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95101731A CN1058615C (en) | 1995-02-15 | 1995-02-15 | Compounded preparation of notoginseng |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95101731A CN1058615C (en) | 1995-02-15 | 1995-02-15 | Compounded preparation of notoginseng |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1129118A CN1129118A (en) | 1996-08-21 |
| CN1058615C true CN1058615C (en) | 2000-11-22 |
Family
ID=5074066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95101731A Expired - Lifetime CN1058615C (en) | 1995-02-15 | 1995-02-15 | Compounded preparation of notoginseng |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1058615C (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1064258C (en) * | 1998-03-17 | 2001-04-11 | 昆明制药股份有限公司 | Pseudo-ginseng extract soft capsule and preparation technology thereof |
| CN100417387C (en) * | 2004-06-17 | 2008-09-10 | 秦引林 | Compound injection formulation compose dof borneol and pseudo-ginseng total saponin and its preparing method |
| CN101773179B (en) * | 2010-03-19 | 2012-07-18 | 马伟光 | Health-caring tea for preventing cardiovascular and cerebrovascular diseases and preparation method thereof |
| CN102940657A (en) * | 2012-10-31 | 2013-02-27 | 成都医路康医学技术服务有限公司 | Medicine composition for treating cardia-cerebrovascular diseases |
| CN105535057A (en) * | 2016-01-09 | 2016-05-04 | 王升云 | Composition capable of assisting in reduction of blood fat and preparing method, preparation and application thereof |
| CN111569008B (en) * | 2020-05-09 | 2021-10-08 | 昆明医科大学 | A pharmaceutical composition for treating neurodegenerative diseases |
| CN112494607A (en) * | 2020-12-09 | 2021-03-16 | 云南中医药大学 | Pharmaceutical composition for preventing and treating cerebral apoplexy and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092317A (en) * | 1993-12-01 | 1994-09-21 | 贺明哲 | Fresh-juice Tianmami (gastrodia tuber sweet) health care food and preparation method thereof |
-
1995
- 1995-02-15 CN CN95101731A patent/CN1058615C/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092317A (en) * | 1993-12-01 | 1994-09-21 | 贺明哲 | Fresh-juice Tianmami (gastrodia tuber sweet) health care food and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1129118A (en) | 1996-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB02 | Change of applicant information |
Applicant after: Kunming Pharmaceutical Co., Ltd. Applicant before: Kunming Pharmaceutical Factory |
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| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: KUNMING PHARMACEUTICAL FACTORY TO: KUNMING MEDICINE STOCK CO., LTD. |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: KUNMING MEDICINE GROUP STOCK CO., LTD. Free format text: FORMER NAME OR ADDRESS: KUNMING MEDICINE STOCK CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Patentee after: Kunming Pharmaceutical Group Co., Ltd Patentee before: Kunming Pharmaceutical Co., Ltd. |
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| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20150215 Granted publication date: 20001122 |