CN112604027A - Nutrient solution for comprehensively solving facial collapse - Google Patents
Nutrient solution for comprehensively solving facial collapse Download PDFInfo
- Publication number
- CN112604027A CN112604027A CN202011531351.7A CN202011531351A CN112604027A CN 112604027 A CN112604027 A CN 112604027A CN 202011531351 A CN202011531351 A CN 202011531351A CN 112604027 A CN112604027 A CN 112604027A
- Authority
- CN
- China
- Prior art keywords
- parts
- nutrient solution
- chinese medicine
- traditional chinese
- medicine extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 56
- 230000001815 facial effect Effects 0.000 title claims abstract description 35
- 239000003814 drug Substances 0.000 claims abstract description 47
- 239000002994 raw material Substances 0.000 claims abstract description 31
- 241001489091 Ganoderma sinense Species 0.000 claims abstract description 24
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 21
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 21
- 102000008186 Collagen Human genes 0.000 claims abstract description 20
- 108010035532 Collagen Proteins 0.000 claims abstract description 20
- 229920001436 collagen Polymers 0.000 claims abstract description 20
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 18
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 18
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 18
- 102000015636 Oligopeptides Human genes 0.000 claims abstract description 13
- 108010038807 Oligopeptides Proteins 0.000 claims abstract description 13
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 11
- 239000000843 powder Substances 0.000 claims description 38
- 239000008176 lyophilized powder Substances 0.000 claims description 34
- 230000001954 sterilising effect Effects 0.000 claims description 25
- 238000004659 sterilization and disinfection Methods 0.000 claims description 23
- 238000002156 mixing Methods 0.000 claims description 21
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 17
- 241000180649 Panax notoginseng Species 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 241000222336 Ganoderma Species 0.000 claims description 13
- 238000004108 freeze drying Methods 0.000 claims description 11
- 238000002360 preparation method Methods 0.000 claims description 11
- 239000000706 filtrate Substances 0.000 claims description 7
- 238000004255 ion exchange chromatography Methods 0.000 claims description 7
- 238000010298 pulverizing process Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- 238000000108 ultra-filtration Methods 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 3
- 235000016709 nutrition Nutrition 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 abstract description 47
- 230000000694 effects Effects 0.000 abstract description 12
- 238000002347 injection Methods 0.000 abstract description 10
- 239000007924 injection Substances 0.000 abstract description 10
- 230000007547 defect Effects 0.000 abstract description 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 2
- 208000026935 allergic disease Diseases 0.000 abstract description 2
- 230000007815 allergy Effects 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 206010020718 hyperplasia Diseases 0.000 abstract description 2
- 230000002045 lasting effect Effects 0.000 abstract description 2
- 239000002245 particle Substances 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 238000011084 recovery Methods 0.000 abstract description 2
- 230000002829 reductive effect Effects 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 43
- 206010040954 Skin wrinkling Diseases 0.000 description 31
- 230000037303 wrinkles Effects 0.000 description 30
- 230000003068 static effect Effects 0.000 description 15
- 210000004709 eyebrow Anatomy 0.000 description 13
- 230000003796 beauty Effects 0.000 description 6
- 239000011148 porous material Substances 0.000 description 5
- 210000003128 head Anatomy 0.000 description 4
- 230000032683 aging Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 229920001184 polypeptide Polymers 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 210000001061 forehead Anatomy 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 102000029816 Collagenase Human genes 0.000 description 1
- 108060005980 Collagenase Proteins 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 208000021401 Facial Nerve injury Diseases 0.000 description 1
- 206010064571 Gene mutation Diseases 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 206010018852 Haematoma Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 206010051246 Photodermatosis Diseases 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- 206010040825 Skin depigmentation Diseases 0.000 description 1
- 206010040893 Skin necrosis Diseases 0.000 description 1
- 206010040925 Skin striae Diseases 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 229960002424 collagenase Drugs 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000035614 depigmentation Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000887 face Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- -1 flavonoid compounds Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 230000008845 photoaging Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000036560 skin regeneration Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3637—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the origin of the biological material other than human or animal, e.g. plant extracts, algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
Abstract
The invention discloses a nutrient solution for comprehensively solving facial collapse, which comprises the following raw materials in parts by weight: 12-18 parts of collagen, 3-8 parts of hyaluronic acid, 3-8 parts of oligopeptide, 1.6-2.4 parts of traditional Chinese medicine extract and 20-30 parts of normal saline; the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 8-12 parts of pseudo-ginseng and 8-12 parts of ganoderma sinensis. The invention has the beneficial effects that: the nutrient solution for comprehensively solving the facial collapse can ensure that the face is full, clear in lines and young, and the defects of fat particles and fat hyperplasia can be reduced; the nutrient solution solves the problem that non-absorbable injection has potential safety hazard, does not generate phenomena of allergy, rejection and the like, has natural effect and lasting effect, and has no risk and no wound in the using process and short recovery period because the nutrient solution adopts an injection mode.
Description
Technical Field
The invention belongs to the technical field of medical cosmetology, and particularly relates to a nutrient solution for comprehensively solving facial collapse.
Background
The skin is a protective barrier of the human body, so that the human body is not damaged by external natural factors and environmental pollution, excessive water can be prevented from being lost from the body, when the skin is subjected to external stimulation or physical damage, the barrier is damaged, physical and chemical indexes of the skin are abnormal, such as dryness, dermatitis, skin darkness, color spots, abnormal keratinization and aging of cutin and the like, when the damage is further aggravated, the skin can generate inflammatory factors and a large number of free radicals, finally scars can be generated, the skin is sunken, and the attractiveness is influenced.
The hyaluronic acid filling agent is injected and filled on the face of a beauty-seeking person to improve the defect of facial depression, and is a very common non-operative medical beauty technique at present. However, the existing operation methods are insufficient in supplementary capacity, have large side effects, and consider less overall facial coordination and later-stage nursing of beauty requesters, so that the requirements of the beauty requesters cannot be met.
Disclosure of Invention
The invention aims to provide a nutrient solution for comprehensively solving the facial collapse.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides a nutrient solution for comprehensively solving face collapse, which comprises the following raw materials in parts by weight: 12-18 parts of collagen, 3-8 parts of hyaluronic acid, 3-8 parts of oligopeptide, 1.6-2.4 parts of traditional Chinese medicine extract and 20-30 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 8-12 parts of pseudo-ginseng and 8-12 parts of ganoderma sinensis.
The nutrient solution for comprehensively solving the face collapse comprises the following raw materials in parts by weight as a preferred embodiment: 14-16 parts of collagen, 4-6 parts of hyaluronic acid, 4-6 parts of oligopeptide, 1.9-2.1 parts of traditional Chinese medicine extract and 22-28 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 9-11 parts of pseudo-ginseng and 9-11 parts of ganoderma sinensis.
The nutrient solution for comprehensively solving the face collapse comprises the following raw materials in parts by weight as a preferred embodiment: 15 parts of collagen, 5 parts of hyaluronic acid, 5 parts of oligopeptide, 2 parts of traditional Chinese medicine extract and 25 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 10 parts of pseudo-ginseng and 10 parts of ganoderma sinensis.
Collagen is a biological macromolecule, the main component of the connective tissue of animals, and is also the functional protein with the largest content and the widest distribution in mammals, accounting for 25% -30% of the total protein amount, and the collagen provides a stable and favorable support framework in the skin, thereby being capable of maintaining the plumpness and luster of the skin. Collagen is supported in the skin like a bracket and a spring, and once the spring is broken, the dermal tissue is collapsed, and wrinkles appear; skin can be flaccid and drooped; after the skin produces oil, the enlarged pores can not be retracted and restored due to the reduction of elasticity, and the pores become large, so that the effect of the collagen on the human body is different and small; the injected collagen can smooth the young lines, repair wrinkles, supplement the collagen, directly permeate into the dermis of the skin, reform the fibrous tissue mechanism of the skin, promote the metabolism of cells, delay the aging of the cells, stretch the fine wrinkles and recover the tightness and elasticity of the skin.
Hyaluronic acid generally refers to hyaluronic acid, is an acidic mucopolysaccharide, is a material which can be absorbed by a human body, has good effects of moisturizing skin, maintaining beauty, keeping young and the like, has the effects of removing wrinkles, enlarging lips and filling faces, can be quickly fused with hyaluronic acid of the hyaluronic acid after being injected into the human body through a pinhole, and is safe to use.
Oligopeptides are a class of polypeptides, generally having a molecular weight range of less than 1000 daltons, which are directly absorbed in the human body. Is the only cosmetic component which can obtain the Nobel prize definitely, and is praised as 'beauty factor' by the beauty profession! The infant skin care liquid is widely stored in human bodies or other animals, is small in amount, can smooth pores, stimulate skin activity, accelerate healing of damaged cells and remove acne marks, is rich in oligopeptide-1 in the skin of infants, gradually attenuates the content of the oligopeptide-1 in the skin along with the gradual increase of the skin, and accordingly, the skin is aged, and the youth degree of the skin is determined by the content of the oligopeptide-1. It can promote the synthesis of collagen and collagenase, secrete collagen substances, hyaluronic acid and glycoprotein, moisten skin, enhance skin elasticity, reduce skin wrinkles and prevent skin aging; can repair damaged cells, relieve damage of direct ultraviolet rays to skin, reduce growth of black spots on the skin after sunburn, eliminate gene mutation factors of the damaged cells, and prevent photoaging.
Notoginseng radix is sweet in flavor and warm in nature, and has effects of removing blood stasis, stopping bleeding, promoting blood circulation and relieving pain. The pseudo-ginseng also has the effect of beautifying, the pseudo-ginseng can promote the metabolism of the skin, provide sufficient nutrition for the skin and clear sediments in blood, and flavonoid compounds contained in the pseudo-ginseng have the characteristics of clearing free radicals and inhibiting lipid peroxidation, namely the pseudo-ginseng has a good effect of delaying senility.
The ganoderma sinensis has a long history as a medicine, has sweet smell and warm nature, and the ganoderma sinensis polysaccharide is one of the most important physiological active substances in the ganoderma sinensis extract, can improve the immunity of an organism, improve the oxygen resistance of the organism, eliminate free radicals and play a role in protecting cells and delaying cell aging. The ganoderma sinensis contains rich polypeptide factors, the polypeptide factors can promote skin regeneration, and nutrient components directly reach the bottom of the skin, so that the skin can enjoy the perfect effects of supplementing moisture and lifting and compacting, cell growth can be accelerated, the damaged stratum corneum can be reconstructed, energy can be given to the bottom of the skin, oxygen content is increased, and the skin can be repaired from inside to outside.
In a second aspect of the present application, there is provided a method for preparing a nutritional liquid for comprehensively solving facial collapse, comprising the steps of:
(1) preparing a traditional Chinese medicine extract;
(2) sterilizing the traditional Chinese medicine extract, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
As a preferred embodiment, the preparation method of the nutrient solution for comprehensively solving the facial collapse comprises the following steps: respectively freeze-drying Notoginseng radix and Ganoderma, respectively pulverizing into powder after drying to obtain Notoginseng radix lyophilized powder and Ganoderma lyophilized powder; mixing Notoginseng radix lyophilized powder and Ganoderma sinensis lyophilized powder uniformly to obtain mixed lyophilized powder, adding water into the mixed lyophilized powder, mixing and stirring uniformly, standing, filtering, and collecting filtrate to obtain lyophilized powder extract; performing ion exchange chromatography on the lyophilized powder extract, and collecting the effluent to obtain the Chinese medicinal extract.
The preparation method of the nutrient solution for comprehensively solving the facial collapse is a preferred embodiment, the freeze-drying temperature is-10 ℃ to 0 ℃, and the freeze-drying time at the temperature is 18-28 h.
The preparation method of the nutrient solution for comprehensively solving the face collapse is a preferred embodiment, water is added into the mixed freeze-dried powder to be mixed and stirred uniformly, standing is carried out, and ultrafiltration treatment is carried out
As a preferred embodiment, the weight ratio of the mixed freeze-dried powder to water is 1: 6-8.
In the above method for preparing a nutrient solution for comprehensively solving the facial collapse, as a preferred embodiment, in the step (2), the sterilization is ultrasonic sterilization.
As a preferable embodiment, the ultrasonic frequency of the ultrasonic sterilization is 15-30KHz, and the ultrasonic sterilization time is 10-50 min.
Compared with the prior art, the invention has the beneficial effects that:
the nutrient solution for comprehensively solving the facial collapse can ensure that the face is full, clear in lines and young, and the defects of fat particles and fat hyperplasia can be reduced; the nutrient solution solves the problem that non-absorbable injection has potential safety hazard, does not generate phenomena of allergy, rejection and the like, has natural effect and lasting effect, and has no risk and no wound in the using process and short recovery period because the nutrient solution adopts an injection mode.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In the examples of the present invention, 1 part by weight represents 1 g.
Example 1
A nutrient solution for comprehensively solving face collapse comprises the following raw materials in parts by weight: 12 parts of collagen, 3 parts of hyaluronic acid, 3 parts of oligopeptide, 1.6 parts of traditional Chinese medicine extract and 20 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 8 parts of pseudo-ginseng and 8 parts of ganoderma sinensis.
The preparation method of the nutrient solution for comprehensively solving the facial collapse comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
respectively freeze-drying Notoginseng radix and Ganoderma at 0 deg.C for 28 hr, and respectively pulverizing into powder to obtain Notoginseng radix lyophilized powder and Ganoderma sinensis lyophilized powder; uniformly mixing the pseudo-ginseng freeze-dried powder and the ganoderma sinensis freeze-dried powder to prepare mixed freeze-dried powder, adding water into the mixed freeze-dried powder, and uniformly mixing and stirring, wherein the weight ratio of the mixed freeze-dried powder to the water is 1: standing, performing ultrafiltration treatment, and collecting filtrate to obtain lyophilized powder extract; performing ion exchange chromatography on the lyophilized powder extract, and collecting eluate to obtain Chinese medicinal extract;
(2) and (3) carrying out ultrasonic sterilization on the traditional Chinese medicine extract, wherein the ultrasonic frequency of the ultrasonic sterilization is 15KHz, the ultrasonic sterilization time is 50min, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
Example 2
A nutrient solution for comprehensively solving face collapse comprises the following raw materials in parts by weight: 14 parts of collagen, 4 parts of hyaluronic acid, 4 parts of oligopeptide, 1.9 parts of traditional Chinese medicine extract and 22 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 9 parts of pseudo-ginseng and 9 parts of ganoderma sinensis.
The preparation method of the nutrient solution for comprehensively solving the facial collapse comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
respectively freeze-drying Notoginseng radix and Ganoderma at-2 deg.C for 25 hr, and respectively pulverizing into powder to obtain Notoginseng radix lyophilized powder and Ganoderma lyophilized powder; uniformly mixing the pseudo-ginseng freeze-dried powder and the ganoderma sinensis freeze-dried powder to prepare mixed freeze-dried powder, adding water into the mixed freeze-dried powder, and uniformly mixing and stirring, wherein the weight ratio of the mixed freeze-dried powder to the water is 1: standing, performing ultrafiltration treatment, and collecting filtrate to obtain lyophilized powder extract; performing ion exchange chromatography on the lyophilized powder extract, and collecting eluate to obtain Chinese medicinal extract;
(2) and (3) carrying out ultrasonic sterilization on the traditional Chinese medicine extract, wherein the ultrasonic frequency of the ultrasonic sterilization is 18KHz, the ultrasonic sterilization time is 40min, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
Example 3
A nutrient solution for comprehensively solving face collapse comprises the following raw materials in parts by weight: 15 parts of collagen, 5 parts of hyaluronic acid, 5 parts of oligopeptide, 2 parts of traditional Chinese medicine extract and 25 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 10 parts of pseudo-ginseng and 10 parts of ganoderma sinensis.
The preparation method of the nutrient solution for comprehensively solving the facial collapse comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
respectively freeze-drying Notoginseng radix and Ganoderma at-5 deg.C for 22 hr, and respectively pulverizing into powder to obtain Notoginseng radix lyophilized powder and Ganoderma lyophilized powder; uniformly mixing the pseudo-ginseng freeze-dried powder and the ganoderma sinensis freeze-dried powder to prepare mixed freeze-dried powder, adding water into the mixed freeze-dried powder, and uniformly mixing and stirring, wherein the weight ratio of the mixed freeze-dried powder to the water is 1: 7, standing, performing ultrafiltration treatment, and collecting filtrate to obtain a freeze-dried powder extracting solution; performing ion exchange chromatography on the lyophilized powder extract, and collecting eluate to obtain Chinese medicinal extract;
(2) and (3) carrying out ultrasonic sterilization on the traditional Chinese medicine extract, wherein the ultrasonic frequency of the ultrasonic sterilization is 22KHz, the ultrasonic sterilization time is 30min, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
Example 4
A nutrient solution for comprehensively solving face collapse comprises the following raw materials in parts by weight: 16 parts of collagen, 6 parts of hyaluronic acid, 6 parts of oligopeptide, 2.1 parts of traditional Chinese medicine extract and 28 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 11 parts of pseudo-ginseng and 11 parts of ganoderma sinensis.
The preparation method of the nutrient solution for comprehensively solving the facial collapse comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
respectively freeze-drying Notoginseng radix and Ganoderma at-8 deg.C for 20 hr, and respectively pulverizing into powder to obtain Notoginseng radix lyophilized powder and Ganoderma lyophilized powder; uniformly mixing the pseudo-ginseng freeze-dried powder and the ganoderma sinensis freeze-dried powder to prepare mixed freeze-dried powder, adding water into the mixed freeze-dried powder, and uniformly mixing and stirring, wherein the weight ratio of the mixed freeze-dried powder to the water is 1: 7, standing, performing ultrafiltration treatment, and collecting filtrate to obtain a freeze-dried powder extracting solution; performing ion exchange chromatography on the lyophilized powder extract, and collecting eluate to obtain Chinese medicinal extract;
(2) and (3) carrying out ultrasonic sterilization on the traditional Chinese medicine extract, wherein the ultrasonic frequency of the ultrasonic sterilization is 28KHz, the ultrasonic sterilization time is 15min, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
Example 5
A nutrient solution for comprehensively solving face collapse comprises the following raw materials in parts by weight: 18 parts of collagen, 8 parts of hyaluronic acid, 8 parts of oligopeptide, 2.4 parts of traditional Chinese medicine extract and 30 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 12 parts of pseudo-ginseng and 12 parts of ganoderma sinensis.
The preparation method of the nutrient solution for comprehensively solving the facial collapse comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
respectively freeze-drying Notoginseng radix and Ganoderma at-10 deg.C for 18 hr, and respectively pulverizing into powder to obtain Notoginseng radix lyophilized powder and Ganoderma lyophilized powder; uniformly mixing the pseudo-ginseng freeze-dried powder and the ganoderma sinensis freeze-dried powder to prepare mixed freeze-dried powder, adding water into the mixed freeze-dried powder, and uniformly mixing and stirring, wherein the weight ratio of the mixed freeze-dried powder to the water is 1: standing, performing ultrafiltration treatment, and collecting filtrate to obtain lyophilized powder extract; performing ion exchange chromatography on the lyophilized powder extract, and collecting eluate to obtain Chinese medicinal extract;
(2) and (3) carrying out ultrasonic sterilization on the traditional Chinese medicine extract, wherein the ultrasonic frequency of the ultrasonic sterilization is 30KHz, the ultrasonic sterilization time is 10min, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
The invention relates to the research on the efficacy of the nutrient solution for comprehensively solving the facial collapse
1. Experimental methods
30 women (age 25-45 years, mean age 35.67) were selected, and injection site: 10 cases of frontotemporal part, 6 cases of middle face, 5 cases of orbital area, 3 cases of cheek part and 6 cases of whole face;
VISIA skin tests skin spots, pores, wrinkles and texture characteristics before and 3 months after injection and was scored comprehensively for criteria: including mandibular border, nasolabial sulcus, frontal striation, fishtail striation, glabellar striation, adopt 0-3 to represent nothing, slight, obvious, serious 4 grades separately, every grade adds up and is the final score, total score 0-15, the score is higher to indicate the aging degree is more serious, the result is shown in table 1:
remarking:
form scoring criteria for nasolabial folds:
0 minute: when smiling, only slight nasolabial fold is seen;
1 minute: in static state, no obvious nasolabial fold and nasolabial ridge are seen, and in smile, obvious fold is seen;
and 2, dividing: in a static state, obvious nasolabial fold lines and nasolabial ridges can be seen, but the nasolabial ridges do not exceed the nasolabial ridges;
and 3, dividing: in static state, a deeper nasolabial fold is visible, extending anteriorly beyond the nasolabial fold.
Morphological scoring criteria of mandibular border:
0 is divided into: when sitting at the head and the lower head, the lower jaw edge has no wrinkles;
1 is divided into: when sitting up and looking flat, the lower jaw edge is clear, the skin has no wrinkles, and when the head is lowered, fine and shallow wrinkles appear;
2, dividing into: when sitting up and looking flat, the lower jaw edge is not obvious, the skin has fine and shallow wrinkles, and when the head is raised, the wrinkles disappear;
3, dividing into: when sitting flat, the lower jaw has obvious proud flesh, the skin wrinkles are thick and deep, and the wrinkles do not disappear when looking up.
Morphology scoring criteria for crow's feet:
0 is divided into: in smile, the skin is only raised at the outer canthus of the eye, and no obvious fishtail line is formed;
1 is divided into: in static state, no obvious eye wrinkles are seen, and in smile, fishtail lines are formed;
2, dividing into: when the skin is static, obvious fishtail lines can be seen, but no obvious wrinkles are formed, and the wrinkles can disappear by pulling the skin on two sides of the wrinkles;
3, dividing into: in static state, deeper fishtail lines can be seen, wrinkles are formed, and wrinkles on both sides of the pulled wrinkles cannot disappear.
Morphology scoring criteria for frontal lines:
0 is divided into: no forehead lines are seen in a static state, and only slight skin lines are deepened when the eyebrows are lifted;
1 is divided into: slight forehead wrinkles can be seen in a static state, and the eyebrows can be deepened when lifted, so that clear wrinkles can be formed;
2, dividing into: obvious frontal wrinkles can be seen in a static state, the eyebrow lifting becomes deeper, and the number of the wrinkles is more than that in the static state;
3, dividing into: deeper frontal wrinkles were visible in the static state, and after leveling with the hand, obvious depression marks were still visible.
Morphology scoring criteria for eyebrow striae:
0 is divided into: no eyebrow lines are seen in a static state, and only skin bulges appear when eyebrows are wrinkled;
1 is divided into: slight lines between eyebrows can be seen in a static state, and the lines between eyebrows are deepened when eyebrows are wrinkled, so that clear wrinkles are formed;
2, dividing into: the eyebrow lines are visible in a static state, eyebrow wrinkles become deeper, and eyebrow wrinkles extend to the periphery along the original eyebrows;
and 3, the deep glabellar lines can be seen in a static state, and obvious depression traces can still be seen after the glabellar lines are smoothed by hands.
TABLE 1 VISIA score before and after the nutrient solution of the present invention was injected
| Speckle | Pores of skin | Wrinkle (wrinkle) | Texture | |
| Before injection | 14.62±2.11 | 13.89±2.56 | 14.78±1.89 | 13.56±2.07 |
| After injection | 8.39±1.98 | 8.13±2.01 | 8.56±1.59 | 8.89±2.01 |
As can be seen from table 1: the nutrient solution for comprehensively solving the facial collapse can play a good filling effect by being injected.
The nutrient solution for comprehensively solving the facial collapse is safe to use, and has the advantages that all the patients with the injection follow-up visit lasts for 3-15 months, no obvious visual swelling is generated 10 days after the injection, the postoperative effect is obvious, the two sides are symmetrical, and none of the patients has complications such as hematoma, skin necrosis, infection, facial nerve injury, skin pigmentation or depigmentation.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims (10)
1. The nutrient solution for comprehensively solving the face collapse is characterized by comprising the following raw materials in parts by weight: 12-18 parts of collagen, 3-8 parts of hyaluronic acid, 3-8 parts of oligopeptide, 1.6-2.4 parts of traditional Chinese medicine extract and 20-30 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 8-12 parts of pseudo-ginseng and 8-12 parts of ganoderma sinensis.
2. The nutrient solution for comprehensively solving the face collapse according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 14-16 parts of collagen, 4-6 parts of hyaluronic acid, 4-6 parts of oligopeptide, 1.9-2.1 parts of traditional Chinese medicine extract and 22-28 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 9-11 parts of pseudo-ginseng and 9-11 parts of ganoderma sinensis.
3. The nutrient solution for comprehensively solving the face collapse according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 15 parts of collagen, 5 parts of hyaluronic acid, 5 parts of oligopeptide, 2 parts of traditional Chinese medicine extract and 25 parts of normal saline;
the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 10 parts of pseudo-ginseng and 10 parts of ganoderma sinensis.
4. A method for preparing a nutritional liquid for comprehensively solving facial collapse as claimed in any one of claims 1 to 3, comprising the steps of:
(1) preparing a traditional Chinese medicine extract;
(2) sterilizing the traditional Chinese medicine extract, and uniformly mixing the sterilized traditional Chinese medicine extract with the rest raw materials in the nutrient solution to obtain the nutrient solution for comprehensively solving the facial collapse.
5. The preparation method of the nutrient solution for comprehensively solving the facial collapse as claimed in claim 4, wherein the preparation method of the traditional Chinese medicine extract comprises the following steps: respectively freeze-drying Notoginseng radix and Ganoderma, respectively pulverizing into powder after drying to obtain Notoginseng radix lyophilized powder and Ganoderma lyophilized powder; mixing Notoginseng radix lyophilized powder and Ganoderma sinensis lyophilized powder uniformly to obtain mixed lyophilized powder, adding water into the mixed lyophilized powder, mixing and stirring uniformly, standing, filtering, and collecting filtrate to obtain lyophilized powder extract; performing ion exchange chromatography on the lyophilized powder extract, and collecting the effluent to obtain the Chinese medicinal extract.
6. The method for preparing the nutrient solution for comprehensively solving the facial collapse as claimed in claim 5, wherein the temperature of freeze-drying is from-10 ℃ to 0 ℃, and the time of freeze-drying at the temperature is from 18 to 28 hours.
7. The method for preparing the nutrient solution for comprehensively solving the facial collapse as claimed in claim 5, wherein water is added into the mixed freeze-dried powder, the mixture is uniformly mixed and stirred, and the mixture is kept stand and subjected to ultrafiltration treatment.
8. The preparation method of the nutrient solution for comprehensively solving the facial collapse as claimed in claim 5, wherein the weight ratio of the mixed freeze-dried powder to water is 1: 6-8.
9. The method for preparing the nutrient solution for comprehensively solving the facial collapse as claimed in claim 4, wherein in the step (2), the sterilization is ultrasonic sterilization.
10. The method for preparing the nutrient solution for comprehensively solving the facial collapse as claimed in claim 9, wherein the ultrasonic frequency of the ultrasonic sterilization is 15-30KHz, and the ultrasonic sterilization time is 10-50 min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011531351.7A CN112604027A (en) | 2020-12-22 | 2020-12-22 | Nutrient solution for comprehensively solving facial collapse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011531351.7A CN112604027A (en) | 2020-12-22 | 2020-12-22 | Nutrient solution for comprehensively solving facial collapse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112604027A true CN112604027A (en) | 2021-04-06 |
Family
ID=75244123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011531351.7A Pending CN112604027A (en) | 2020-12-22 | 2020-12-22 | Nutrient solution for comprehensively solving facial collapse |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112604027A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114146219A (en) * | 2021-12-29 | 2022-03-08 | 上海璞聚生物科技有限公司 | Soft tissue filler and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140301958A1 (en) * | 2011-04-21 | 2014-10-09 | Krzysztof Bojanowski | Transoral methods and compositions for wrinkle reduction and cosmetic lip and facial augmentation |
| CN108096145A (en) * | 2018-01-09 | 2018-06-01 | 广州环亚化妆品科技有限公司 | A kind of delay aging drug composition and its preparation method and application |
| CN109528612A (en) * | 2019-01-18 | 2019-03-29 | 广州市普高管理咨询有限公司 | Crease-resistant tightening cosmetic composition, lotion and its preparation method and application |
| CN109528642A (en) * | 2018-12-27 | 2019-03-29 | 上海欧邦医疗管理有限公司 | A kind of autogenous repairing nutrient injection and its application method |
| CN110279593A (en) * | 2019-05-31 | 2019-09-27 | 上海欧邦医疗管理有限公司 | A kind of compounding nutrient solution for comprehensive solution eye circumference aging |
| CN110801516A (en) * | 2019-10-30 | 2020-02-18 | 通化力神保健品有限公司 | Eye nutrient spray liquid and preparation method thereof |
-
2020
- 2020-12-22 CN CN202011531351.7A patent/CN112604027A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140301958A1 (en) * | 2011-04-21 | 2014-10-09 | Krzysztof Bojanowski | Transoral methods and compositions for wrinkle reduction and cosmetic lip and facial augmentation |
| CN108096145A (en) * | 2018-01-09 | 2018-06-01 | 广州环亚化妆品科技有限公司 | A kind of delay aging drug composition and its preparation method and application |
| CN109528642A (en) * | 2018-12-27 | 2019-03-29 | 上海欧邦医疗管理有限公司 | A kind of autogenous repairing nutrient injection and its application method |
| CN109528612A (en) * | 2019-01-18 | 2019-03-29 | 广州市普高管理咨询有限公司 | Crease-resistant tightening cosmetic composition, lotion and its preparation method and application |
| CN110279593A (en) * | 2019-05-31 | 2019-09-27 | 上海欧邦医疗管理有限公司 | A kind of compounding nutrient solution for comprehensive solution eye circumference aging |
| CN110801516A (en) * | 2019-10-30 | 2020-02-18 | 通化力神保健品有限公司 | Eye nutrient spray liquid and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 谢秀琼: "《现代中药制剂新技术》", 30 June 2004, 化学工业出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114146219A (en) * | 2021-12-29 | 2022-03-08 | 上海璞聚生物科技有限公司 | Soft tissue filler and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107496309A (en) | Antiallergic Face-protecting mask | |
| CN109512691A (en) | A kind of indigo plant copper peptide freeze-dried powder preparation and preparation method thereof | |
| CN104983646A (en) | Night maintenance mask solution and preparation method thereof | |
| CN110664650A (en) | Multi-effect skin care composition and essence and preparation method thereof | |
| CN109044941B (en) | Skin firming, nourishing and moisturizing composition and preparation method and application thereof | |
| CN109431854A (en) | A kind of bFGF acne hole maintenance freeze-dried powder preparation and preparation method thereof | |
| CN106309260B (en) | A kind of Radix Notoginseng is preserved youthful looks facial mask | |
| CN106333909B (en) | A kind of desalination red blood trace on face repairs the lotion and preparation method thereof of skin | |
| CN105267123A (en) | Whitening and hydrating toner and method for manufacturing same | |
| CN113384482B (en) | Moisturizing and skin-tendering essence and preparation method thereof | |
| KR102014979B1 (en) | Mask pack with improved elasticity manufactured by using biodegradable polymer and loess, and the method for manufacturing the mask pack | |
| CN112604027A (en) | Nutrient solution for comprehensively solving facial collapse | |
| CN110559226A (en) | Whitening lotion and preparation method thereof | |
| CN106333880B (en) | toner based on thin emulsion and preparation method thereof | |
| CN108653060A (en) | One kind is dispelled pregnant line face cream | |
| CN110859758A (en) | Whitening anti-aging repair type medical cold compress patch and preparation method thereof | |
| CN111759762A (en) | Black eye removing composition, essence and preparation method thereof | |
| CN104188859A (en) | Anti-wrinkle skin-tendering emulsion containing natural component extracts and preparation method thereof | |
| CN106362053A (en) | Externally-applied traditional Chinese medicine composition with function of removing couperose skin and skin-care preparation of composition | |
| CN110613643A (en) | Repair wrinkle-removing cream and preparation method thereof | |
| CN107441340B (en) | Hand and foot chap cream for relieving swelling, pain and itching and nourishing skin and preparation method thereof | |
| CN114159341A (en) | Freeze-dried eye patch and preparation method thereof | |
| CN109646359B (en) | Rose-agaric mud membrane paste with effects of cleaning, purifying, maintaining beauty and keeping young and preparation method thereof | |
| CN112402319A (en) | Nutrient solution for improving skin quality and preparation and use methods thereof | |
| CN113876656A (en) | Black eye and pouch removing soluble beautifying microneedle patch composition and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210406 |
|
| RJ01 | Rejection of invention patent application after publication |