CN112402319A - Nutrient solution for improving skin quality and preparation and use methods thereof - Google Patents
Nutrient solution for improving skin quality and preparation and use methods thereof Download PDFInfo
- Publication number
- CN112402319A CN112402319A CN202011372506.7A CN202011372506A CN112402319A CN 112402319 A CN112402319 A CN 112402319A CN 202011372506 A CN202011372506 A CN 202011372506A CN 112402319 A CN112402319 A CN 112402319A
- Authority
- CN
- China
- Prior art keywords
- parts
- skin
- chinese medicine
- traditional chinese
- medicine extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention discloses a nutrient solution for improving skin conditions, which comprises the following raw materials in parts by weight: 20-30 parts of collagen, 5-10 parts of oligopeptide, 0.8-1.2 parts of traditional Chinese medicine extract, 0.5-0.8 part of vitamin E and 60-80 parts of normal saline; the traditional Chinese medicine extract comprises the following components: 5-15 parts of salvia miltiorrhiza, 4-6 parts of ligusticum wallichii, 5-15 parts of lucid ganoderma and 10-20 parts of bighead atractylodes rhizome. The invention has the beneficial effects that: the nutrient solution can control the metabolism of pathological cells, eliminate the pathological cells and optimize skin tissues; can promote the regeneration of cutin, remove aged cutin, and improve dark and rough skin; the skin conditioning cream has the effects of conditioning skin, enabling the skin to be fine and elastic, and having remarkable effects on whelk, dark spots and large pores; can supplement nutrients required by the skin, moisten and compact the skin, promote the synthesis and absorption of skin collagen, smooth wrinkles, slow down aging, greatly brighten the skin, enhance the stability of the skin tissue structure, make the skin tender and white and have luster, fundamentally improve the skin quality and make the skin in a young state.
Description
Technical Field
The invention belongs to the technical field of medical cosmetology, and particularly relates to a nutrient solution for improving skin quality and a preparation method thereof.
Background
Along with the continuous development and progress of society, people pay more and more attention to maintenance, so that the personal image is improved, the quality of the personal image can influence the self-confidence of one person from the side, and meanwhile, certain power can be brought to the person to better meet surrounding friends; the skin care product is a product for protecting skin and is divided into a mask, an eye cream, a cream, an essence, a face cleanser, a stock solution and the like, and the skin care product is not a product used by only a few people in the past due to continuous progress of social and economic benefits and abundant material life, and the skin care product enters common families, each family uses different skin care products, and the skin care product plays a great role in improving the spirit and the image of people.
The existing skin care products have multiple functions, such as whitening, moisturizing, deoiling, acne removing and the like, most people can select a skin care product according to the skin condition of the people to improve the skin condition of the people and improve the image of the people, and the nutrient solution for improving the skin condition and the preparation method thereof are provided.
Disclosure of Invention
The invention aims to provide a nutrient solution which is helpful for improving skin quality and a preparation method and a use method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
in a first aspect of the invention, a nutrient solution for improving skin quality is provided, which comprises the following raw materials in parts by weight: 20-30 parts of collagen, 5-10 parts of oligopeptide, 0.8-1.2 parts of traditional Chinese medicine extract, 0.5-0.8 part of vitamin E and 60-80 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 5-15 parts of salvia miltiorrhiza, 4-6 parts of ligusticum wallichii, 5-15 parts of lucid ganoderma and 10-20 parts of bighead atractylodes rhizome.
The nutrient solution for improving skin quality comprises the following raw materials in parts by weight as a preferred embodiment: 22-28 parts of collagen, 6-9 parts of oligopeptide, 0.9-1.1 parts of traditional Chinese medicine extract, 0.6-0.7 part of vitamin E and 65-75 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 8-12 parts of salvia miltiorrhiza, 4-5 parts of ligusticum wallichii, 8-12 parts of lucid ganoderma and 12-18 parts of bighead atractylodes rhizome.
The nutrient solution for improving skin quality comprises the following raw materials in parts by weight as a preferred embodiment: 25 parts of collagen, 7 parts of oligopeptide, 1.0 part of traditional Chinese medicine extract, 0.65 part of vitamin E and 70 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 10 parts of salvia miltiorrhiza, 4.5 parts of ligusticum wallichii, 10 parts of lucid ganoderma and 15 parts of bighead atractylodes rhizome.
Collagen is a biological macromolecule, the main component of the connective tissue of animals, and is also the functional protein with the largest content and the widest distribution in mammals, accounting for 25% -30% of the total protein amount, and the collagen provides a stable and favorable support framework in the skin, thereby being capable of maintaining the plumpness and luster of the skin. Collagen is supported in the skin like a bracket and a spring, and once the spring is broken, the dermal tissue is collapsed, and wrinkles appear; skin can be flaccid and drooped; after the skin produces oil, the enlarged pores can not be retracted and restored due to the reduction of elasticity, and the pores become large, so that the effect of the collagen on the human body is different and small; the injected collagen can smooth the young lines, repair wrinkles, supplement the collagen, directly permeate into the dermis of the skin, reform the fibrous tissue mechanism of the skin, promote the metabolism of cells, delay the aging of the cells, stretch the fine wrinkles and recover the tightness and elasticity of the skin.
Oligopeptides are a class of polypeptides, generally having a molecular weight range of less than 1000 daltons, which are directly absorbed in the human body. Is the only cosmetic component which can obtain the Nobel prize definitely, and is praised as 'beauty factor' by the beauty profession! The infant skin care liquid is widely stored in human bodies or other animals, is small in amount, can smooth pores, stimulate skin activity, accelerate healing of damaged cells and remove acne marks, is rich in oligopeptide-1 in the skin of infants, gradually attenuates the content of the oligopeptide-1 in the skin along with the gradual increase of the skin, and accordingly, the skin is aged, and the youth degree of the skin is determined by the content of the oligopeptide-1. It can promote the synthesis of collagen and collagenase, secrete collagen substances, hyaluronic acid and glycoprotein, moisten skin, enhance skin elasticity, reduce skin wrinkles and prevent skin aging; can repair damaged cells, relieve damage of direct ultraviolet rays to skin, reduce growth of black spots on the skin after sunburn, eliminate gene mutation factors of the damaged cells, and prevent photoaging.
Vitamin E has antioxidant effect, and can protect sebum, cell membrane protein and skin water, promote human cell regeneration and activity, delay cell aging process, and reduce skin infection. It has effects of moistening collagen fiber and elastic fiber in skin, improving and maintaining skin elasticity, promoting blood circulation in skin, providing sufficient nutrition and water for skin, maintaining skin tenderness and luster, inhibiting formation of pigmented spot and senile plaque, reducing facial wrinkle, whitening skin, and preventing acne.
The red sage root is bitter and slightly cold in taste, and the red sage root extract has a good effect of promoting collagen proliferation, so that the red sage root extract can enhance the metabolism of the dermal layer of the skin, has the oxygen resistance, and has the effects of resisting inflammation, wrinkles and bacteria.
The rhizoma Ligustici Chuanxiong contains various alkaloids such as ligustrazine, phenolic substances such as ferulic acid, volatile oil, and vitamins. Ligustrazine can dilate blood vessels, reduce vascular resistance and obviously increase blood flow of limbs; has inhibitory effect on various pathogenic bacteria and viruses; has effect in resisting vitamin E deficiency. Ligustrazine has effects of inhibiting melanocyte proliferation, melanin synthesis, and tyrosinase activity on melanocyte cultured in vitro.
Ganoderma has effects in relieving inflammation, inhibiting bacteria, relaxing bowels, removing toxic substances, improving sleep, preventing wrinkle, scavenging free radicals, improving blood circulation, improving skin elasticity, and supplementing trace elements. The basis of ganoderma lucidum is to clean blood, dredge subcutaneous capillaries, reduce the content of lipid peroxide in blood and insoluble collagen in skin, keep skin luster and elasticity and reduce wrinkles by means of the ganoderma lucidum.
The white atractylodes rhizome has the special effects of whitening skin, removing acne, eliminating spots, clearing heat, drying dampness, sterilizing and the like; the skin characteristics of black, yellow, multiple spots, acnes and the like of the skin caused by natural or postnatal insolation or excessive use of cosmetics of the active ingredients contained in the bighead atractylodes rhizome can be effectively solved. The rhizoma atractylodis macrocephalae has an antioxidation effect and can effectively delay aging.
In a second aspect of the present application, there is provided a method for preparing a nutritional liquid for improving skin texture, comprising the steps of:
(1) preparing a traditional Chinese medicine extract;
(2) sterilizing the traditional Chinese medicine extract, adding the sterilized traditional Chinese medicine extract, collagen and oligopeptide into physiological saline, mixing and stirring uniformly to obtain a mixed solution, and dropwise adding vitamin E into the mixed solution to obtain the nutrient solution for improving skin.
The above-mentioned method for preparing a nutrient solution for improving skin conditions, as a preferred embodiment,
in the step (1), the preparation method of the traditional Chinese medicine extract comprises the following steps:
a. soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water;
b. and c, decocting the soaked substance obtained in the step a, filtering to obtain an extracting solution after the decoction is finished, and concentrating and drying the extracting solution to obtain the traditional Chinese medicine extract.
The above method for preparing a nutrient solution for improving skin conditions, as a preferred embodiment, comprises the steps of: the amount of water is 10-15 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma, and the soaking time is 18-26 h.
The preparation method of the nutrient solution for improving skin conditions is that as a preferred embodiment, the decoction is: decocting the soaked materials at 90-100 deg.C for 20-30min, and decocting at 50-60 deg.C for 40-60 min.
The preparation method of the nutrient solution for improving skin conditions is that as a preferred embodiment, the filtration is: filtering by using a filter screen with 200-300 meshes; preferably, the drying is freeze-drying; more preferably, the freeze-drying is drying at a temperature of-20 ℃ to-25 ℃ for 20-26 h.
In the above method for preparing a nutrient solution for improving skin conditions, as a preferred embodiment, in the step (2), the sterilization is ultrasonic sterilization.
As a preferable embodiment, the ultrasonic frequency of the ultrasonic sterilization is 15-30KHz, and the ultrasonic sterilization time is 10-50 min.
In a third aspect of the present application, there is provided a method for using a nutritional liquid for improving skin conditions, comprising: injecting the nutrient solution into the skin to be repaired.
Compared with the prior art, the invention has the beneficial effects that: the nutrient solution for improving the skin quality can control the metabolism of pathological cells, eliminate the pathological cells and optimize skin tissues; can promote the regeneration of cutin, remove aged cutin, and is helpful for improving skin problems such as darkness, roughness, uneven skin color, etc.; the skin care cream has the function of conditioning skin, enables the skin to be fine and elastic, and has obvious effects on dry skin, whelk, dark spot and large pore; can supplement nutrients required by the skin, moisten and compact the skin, promote the synthesis and absorption of skin collagen, smooth wrinkles, slow down aging, greatly brighten the skin, enhance the stability of the skin tissue structure, make the skin tender and white and have bright color, fundamentally improve the skin quality, recover the delicate texture of the skin, make the skin soft and smooth and present a young state.
The nutrient solution for improving the skin quality does not have the uncomfortable phenomena of allergy, rejection and the like in the using process, is safe to use and has long efficacy; in the convalescent period after injection, the injection has no discomfortable symptoms such as red swelling, pruritus and the like, and does not influence normal work and life.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In the examples of the present invention, 1 part by weight represents 1 g.
Example 1
A nutrient solution for improving skin quality comprises the following raw materials in parts by weight: 20 parts of collagen, 5 parts of oligopeptide, 0.8 part of traditional Chinese medicine extract, 0.5 part of vitamin E and 60 parts of physiological saline;
the traditional Chinese medicine extract comprises the following components: 5 parts of salvia miltiorrhiza, 4 parts of ligusticum wallichii, 5 parts of lucid ganoderma and 10 parts of bighead atractylodes rhizome.
The preparation method of the nutrient solution for improving the skin quality comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water for 18 hr; the amount of water is 15 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma;
decocting the obtained soaking material at 90 deg.C for 30min, then at 50 deg.C for 60min, filtering with 200 mesh filter screen to obtain extractive solution, concentrating, and drying at-20 deg.C for 26 hr to obtain Chinese medicinal extract;
(2) sterilizing the Chinese medicinal extract with ultrasonic wave at 15KHz for 50min, adding sterilized Chinese medicinal extract, collagen and oligopeptide into physiological saline, mixing and stirring to obtain mixed solution, and adding vitamin E dropwise into the mixed solution to obtain the nutritional liquid for improving skin quality.
Example 2
A nutrient solution for improving skin quality comprises the following raw materials in parts by weight: 22 parts of collagen, 6 parts of oligopeptide, 0.9 part of traditional Chinese medicine extract, 0.6 part of vitamin E and 65 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 8 parts of salvia miltiorrhiza, 4 parts of ligusticum wallichii, 8 parts of lucid ganoderma and 12 parts of bighead atractylodes rhizome.
The preparation method of the nutrient solution for improving the skin quality comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water for 20 hr; the amount of water is 14 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma;
decocting the obtained soaking material at 93 deg.C for 28min, changing to 53 deg.C, decocting for 55min, filtering with 250 mesh filter screen to obtain extractive solution, concentrating, and drying at-22 deg.C for 23 hr to obtain Chinese medicinal extract.
(2) Sterilizing the Chinese medicinal extract with ultrasonic wave at 20KHz for 40min, adding sterilized Chinese medicinal extract, collagen and oligopeptide into physiological saline, mixing and stirring to obtain mixed solution, and adding vitamin E dropwise into the mixed solution to obtain the nutritional liquid for improving skin quality.
Example 3
A nutrient solution for improving skin quality comprises the following raw materials in parts by weight: 25 parts of collagen, 7 parts of oligopeptide, 1.0 part of traditional Chinese medicine extract, 0.65 part of vitamin E and 70 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 10 parts of salvia miltiorrhiza, 4.5 parts of ligusticum wallichii, 10 parts of lucid ganoderma and 15 parts of bighead atractylodes rhizome.
(1) Preparing a traditional Chinese medicine extract:
soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water for 22 hr; the amount of water is 12 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma;
decocting the obtained soaking material at 96 deg.C for 25min, changing to 55 deg.C, decocting for 50min, filtering with 200 mesh filter screen to obtain extractive solution, concentrating, and drying at-22 deg.C for 25 hr to obtain Chinese medicinal extract.
(2) Sterilizing the Chinese medicinal extract with ultrasonic wave at ultrasonic frequency of 25KHz for 35min, adding sterilized Chinese medicinal extract, collagen and oligopeptide into physiological saline, mixing and stirring to obtain mixed solution, and adding vitamin E dropwise into the mixed solution to obtain the nutritional liquid for improving skin quality.
Example 4
A nutrient solution for improving skin quality comprises the following raw materials in parts by weight: 28 parts of collagen, 9 parts of oligopeptide, 1.1 parts of traditional Chinese medicine extract, 0.7 part of vitamin E and 75 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 12 parts of salvia miltiorrhiza, 5 parts of ligusticum wallichii, 12 parts of lucid ganoderma and 18 parts of bighead atractylodes rhizome.
The preparation method of the nutrient solution for improving the skin quality comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water for 25 hr; the amount of water is 12 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma;
decocting the obtained soaking material at 98 deg.C for 22min, then at 58 deg.C for 45min, filtering with 280 mesh filter screen to obtain extractive solution, concentrating, and drying at-23 deg.C for 25 hr to obtain Chinese medicinal extract.
(2) Sterilizing the Chinese medicinal extract with ultrasonic wave at ultrasonic frequency of 25KHz for 15min, adding sterilized Chinese medicinal extract, collagen and oligopeptide into physiological saline, mixing and stirring to obtain mixed solution, and adding vitamin E dropwise into the mixed solution to obtain the nutritional liquid for improving skin quality.
Example 5
A nutrient solution for improving skin quality comprises the following raw materials in parts by weight: 30 parts of collagen, 10 parts of oligopeptide, 1.2 parts of traditional Chinese medicine extract, 0.8 part of vitamin E and 80 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 15 parts of salvia miltiorrhiza, 6 parts of ligusticum wallichii, 15 parts of lucid ganoderma and 20 parts of bighead atractylodes rhizome.
The preparation method of the nutrient solution for improving the skin quality comprises the following steps:
(1) preparing a traditional Chinese medicine extract:
soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water for 26 hr; the amount of water is 10 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma;
decocting the obtained soaking material at 100 deg.C for 20min, further decocting at 60 deg.C for 40min, filtering with 300 mesh filter screen to obtain extractive solution, concentrating, and drying at-25 deg.C for 20 hr to obtain Chinese medicinal extract.
(2) Sterilizing the Chinese medicinal extract with ultrasonic wave at 30KHz for 10min, adding sterilized Chinese medicinal extract, collagen and oligopeptide into physiological saline, mixing and stirring to obtain mixed solution, and adding vitamin E dropwise into the mixed solution to obtain the nutritional liquid for improving skin quality.
1. The research on the efficacy of the nutrient solution for improving the skin quality of the invention
1.1 Experimental methods: 30 volunteers with random gender and age of 25-45 years (average age 30.11) were selected, the nutrient solution for improving skin texture of the present invention was injected once a week, the melanin content in the skin of the injection site was measured before each injection, and the average value was obtained, and the experimental results are shown in table 1.
1.2 detection Instrument
A detection instrument:
a melanin skin test instrument (Mexameter MX18, manufactured by CK electronics, Germany) and a skin oil tester.
TABLE 1 melanin changes in the skin after injection of the nutrient solution for improving skin conditions according to the present invention
| First week | Second week | The third week | The fourth side | |
| Melanin content in skin | 181.96 | 178.31 | 171.56 | 169.35 |
As can be seen from Table 1, the melanin of the skin at the injection site showed a significant decrease after the injection of the skin-improving nutrient solution of the present invention.
2. Study on acne removing effect
2.1 preparing a double-layer plate (the lower layer is culture medium, the upper layer is culture medium containing propionibacterium acnes) containing propionibacterium acnes (ATCC11827), wherein the bacterial content of the plate is 104-105 CFU/plate, after the plate is cooled, accurately weighing 0.5ml of nutrient solution for improving skin quality obtained in the embodiment 1-5, uniformly coating the nutrient solution on the plate containing bacteria by using a sterile cotton swab, culturing for 24 hours at 36 +/-1 ℃ under anaerobic condition, observing the growth condition of bacterial colonies in the plate, and recording the area covered by a bacterial colony growth area in the plate.
2.2 the test results are shown in Table 2:
remarking: when the area covered by the colony growing area in the plate is more than 75 percent, the acne-removing effect is not achieved;
when the area covered by the colony growing area in the plate is 50-75%, the plate is proved to have lower acne-removing efficacy;
when the area covered by the colony growing area in the plate is 25-50%, the plate is proved to have moderate acne-removing efficacy;
when the colony growing area in the plate covers less than 25 percent of the area, the plate is proved to have high-efficiency acne-removing efficacy.
Table 2 research on acne removing effect of the nutrient solution for improving skin according to the present invention
| Area of colony growth | Acne removing effect | |
| Example 1 | 11％ | Efficient |
| Example 2 | 9％ | Efficient |
| Example 3 | 13％ | Efficient |
| Example 4 | 10％ | Efficient |
| Example 5 | 12％ | Efficient |
As can be seen from Table 2, the nutrient solution for improving skin conditions of the invention has better acne-removing efficacy.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims (10)
1. The nutrient solution for improving the skin quality is characterized by comprising the following raw materials in parts by weight: 20-30 parts of collagen, 5-10 parts of oligopeptide, 0.8-1.2 parts of traditional Chinese medicine extract, 0.5-0.8 part of vitamin E and 60-80 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 5-15 parts of salvia miltiorrhiza, 4-6 parts of ligusticum wallichii, 5-15 parts of lucid ganoderma and 10-20 parts of bighead atractylodes rhizome.
2. The nutrient solution for improving skin conditions according to claim 1, comprising the following raw materials in parts by weight: 22-28 parts of collagen, 6-9 parts of oligopeptide, 0.9-1.1 parts of traditional Chinese medicine extract, 0.6-0.7 part of vitamin E and 65-75 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 8-12 parts of salvia miltiorrhiza, 4-5 parts of ligusticum wallichii, 8-12 parts of lucid ganoderma and 12-18 parts of bighead atractylodes rhizome.
3. The nutrient solution for improving skin conditions according to claim 1, comprising the following raw materials in parts by weight: 25 parts of collagen, 7 parts of oligopeptide, 1.0 part of traditional Chinese medicine extract, 0.65 part of vitamin E and 70 parts of normal saline;
the traditional Chinese medicine extract comprises the following components: 10 parts of salvia miltiorrhiza, 4.5 parts of ligusticum wallichii, 10 parts of lucid ganoderma and 15 parts of bighead atractylodes rhizome.
4. A method of preparing a nutritional liquid for improving skin conditions according to any one of claims 1 to 3, comprising the steps of:
(1) preparing a traditional Chinese medicine extract;
(2) sterilizing the traditional Chinese medicine extract, adding the sterilized traditional Chinese medicine extract, collagen and oligopeptide into physiological saline, mixing and stirring uniformly to obtain a mixed solution, and dropwise adding vitamin E into the mixed solution to obtain the nutrient solution for improving skin.
5. The method for preparing a skin-improving nutrient solution according to claim 4, wherein in the step (1), the method for preparing the Chinese medicinal extract comprises the following steps:
a. soaking Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma in water;
b. and c, decocting the soaked substance obtained in the step a, filtering to obtain an extracting solution after the decoction is finished, and concentrating and drying the extracting solution to obtain the traditional Chinese medicine extract.
6. The method for preparing a nutritional liquid for improving skin conditions according to claim 5, wherein in the step a: the amount of water is 10-15 times of the total amount of Saviae Miltiorrhizae radix, rhizoma Ligustici Chuanxiong, Ganoderma, and Atractylodis rhizoma, and the soaking time is 18-26 h.
7. The method of claim 5, wherein said decocting is: decocting the soaked materials at 90-100 deg.C for 20-30min, and decocting at 50-60 deg.C for 40-60 min.
8. The method for preparing a nutritional liquid for improving skin conditions according to claim 5, wherein the filtering is: filtering by using a filter screen with 200-300 meshes; preferably, the drying is freeze-drying; more preferably, the freeze-drying is drying at a temperature of-20 ℃ to-25 ℃ for 20-26 h.
9. The method for preparing a nutritional liquid for improving skin conditions according to claim 4, wherein in the step (2), the sterilization is ultrasonic sterilization; the ultrasonic frequency of the ultrasonic sterilization is 15-30KHz, and the ultrasonic sterilization time is 10-50 min.
10. A method of using a nutritional liquid for improving skin conditions according to any one of claims 1 to 3, comprising: injecting the nutrient solution into the skin to be repaired.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011372506.7A CN112402319A (en) | 2020-11-30 | 2020-11-30 | Nutrient solution for improving skin quality and preparation and use methods thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011372506.7A CN112402319A (en) | 2020-11-30 | 2020-11-30 | Nutrient solution for improving skin quality and preparation and use methods thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112402319A true CN112402319A (en) | 2021-02-26 |
Family
ID=74830659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011372506.7A Pending CN112402319A (en) | 2020-11-30 | 2020-11-30 | Nutrient solution for improving skin quality and preparation and use methods thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112402319A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114392393A (en) * | 2021-12-17 | 2022-04-26 | 重庆米茜尔医疗美容门诊部有限公司 | Subcutaneous injection composition for skin self-repair and use method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008105984A (en) * | 2006-10-25 | 2008-05-08 | Nicca Chemical Co Ltd | Collagen production promoter, skin care preparation for external use, bathing agent, and food and drink |
| WO2016055737A1 (en) * | 2014-10-10 | 2016-04-14 | Basf Beauty Care Solutions France Sas | Deglycation activity of a combination of an extract of salvia miltiorrhiza and of niacin and/or niacinamide |
| CN107028793A (en) * | 2017-05-17 | 2017-08-11 | 天津普瑞赛尔生物科技有限公司 | A kind of reparation stoste based on the human mesenchymal stem cell secretion activity factor and preparation method thereof |
| CN111329808A (en) * | 2020-04-03 | 2020-06-26 | 西安力邦医美科技有限公司 | Cosmetic composition with anti-glycosylation and anti-aging effects and application thereof |
-
2020
- 2020-11-30 CN CN202011372506.7A patent/CN112402319A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008105984A (en) * | 2006-10-25 | 2008-05-08 | Nicca Chemical Co Ltd | Collagen production promoter, skin care preparation for external use, bathing agent, and food and drink |
| WO2016055737A1 (en) * | 2014-10-10 | 2016-04-14 | Basf Beauty Care Solutions France Sas | Deglycation activity of a combination of an extract of salvia miltiorrhiza and of niacin and/or niacinamide |
| CN107028793A (en) * | 2017-05-17 | 2017-08-11 | 天津普瑞赛尔生物科技有限公司 | A kind of reparation stoste based on the human mesenchymal stem cell secretion activity factor and preparation method thereof |
| CN111329808A (en) * | 2020-04-03 | 2020-06-26 | 西安力邦医美科技有限公司 | Cosmetic composition with anti-glycosylation and anti-aging effects and application thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114392393A (en) * | 2021-12-17 | 2022-04-26 | 重庆米茜尔医疗美容门诊部有限公司 | Subcutaneous injection composition for skin self-repair and use method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520081A (en) | External skin care product capable of adjusting skin immunity and delaying skin aging | |
| CN104434618B (en) | Have whitening, nti-freckle concurrently and print nine grass green frosts of effect and preparation method thereof | |
| CN110664650A (en) | Multi-effect skin care composition and essence and preparation method thereof | |
| CN106727002A (en) | A kind of eye cream of multi-efficiency and preparation method thereof | |
| CN110123729A (en) | A kind of jelly film and preparation method thereof | |
| CN109044941B (en) | Skin firming, nourishing and moisturizing composition and preparation method and application thereof | |
| CN107536798A (en) | A kind of female sex organ care compositions | |
| CN106309260B (en) | A kind of Radix Notoginseng is preserved youthful looks facial mask | |
| CN111840201A (en) | Anti-aging and repairing composite preparation containing stem cell factor and preparation method thereof | |
| CN108670933B (en) | Skin care composition with moisturizing, whitening and anti-aging functions and application thereof | |
| CN110559226A (en) | Whitening lotion and preparation method thereof | |
| CN111265441A (en) | Composition capable of enhancing skin night repair and regeneration capacity and application thereof | |
| CN108309873B (en) | Activation-balanced conditioning essence | |
| CN104825347A (en) | Medical biological whitening and spot-removing dressing and preparation method thereof | |
| CN107157859A (en) | A kind of face mask of traditional Chinese medicine with nti-freckle, whitening and nourishing effect and preparation method thereof | |
| CN112402319A (en) | Nutrient solution for improving skin quality and preparation and use methods thereof | |
| CN113057903A (en) | Polypeptide micro-protein mask solution, preparation method thereof and polypeptide micro-protein mask | |
| CN111759762A (en) | Black eye removing composition, essence and preparation method thereof | |
| CN110859758A (en) | Whitening anti-aging repair type medical cold compress patch and preparation method thereof | |
| CN110613643A (en) | Repair wrinkle-removing cream and preparation method thereof | |
| CN112402595A (en) | Nutrient solution for comprehensively solving eye aging and preparation and use methods thereof | |
| CN107281057A (en) | A kind of anti-acne spot-relieving face mask and preparation method thereof | |
| CN114767608A (en) | Natural plant maintenance and rejuvenation compound skin care product raw material, and preparation method and application thereof | |
| CN112604027A (en) | Nutrient solution for comprehensively solving facial collapse | |
| CN113876656A (en) | Black eye and pouch removing soluble beautifying microneedle patch composition and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210226 |
|
| RJ01 | Rejection of invention patent application after publication |