CN112567049A - 鉴定胃癌状态的方法和试剂盒 - Google Patents

鉴定胃癌状态的方法和试剂盒 Download PDF

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CN112567049A
CN112567049A CN201880095978.7A CN201880095978A CN112567049A CN 112567049 A CN112567049 A CN 112567049A CN 201880095978 A CN201880095978 A CN 201880095978A CN 112567049 A CN112567049 A CN 112567049A
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李明明
李淑钰
陈彦利
徐春叶
蒲珏
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Beijing Aikelun Medical Technology Co ltd
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Abstract

一种在受试者中鉴定胃癌状态的方法,包括:1)从所述受试者采集生物样品;2)检测所述生物样品中生物标志物基因的甲基化水平,其中所述生物标志物基因选自如下基因的一种或多种:CDH1、DAPK、PAX5、RASSF1A、Reprimo、RNF180、RUNX3、SDC2、Septin9和TCF4;以及3)将步骤2)检测的甲基化水平与群体中相应生物标志物基因的正常甲基化水平进行比较,以确定所述受试者中的胃癌状态。还提供了用于鉴定受试者中胃癌状态的试剂盒。所提供的方法和试剂盒为胃癌的预测、诊断、和评估提供了一条快速、可靠、准确的新途径。

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PCT国内申请,说明书已公开。

Claims (36)

  1. PCT国内申请,权利要求书已公开。
CN201880095978.7A 2018-07-26 2018-07-26 鉴定胃癌状态的方法和试剂盒 Pending CN112567049A (zh)

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PCT/CN2018/097297 WO2020019269A1 (zh) 2018-07-26 2018-07-26 鉴定胃癌状态的方法和试剂盒

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US (1) US20210222260A1 (zh)
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CN113186282A (zh) * 2021-04-29 2021-07-30 北京艾克伦医疗科技有限公司 鉴定胰腺癌状态的方法和试剂盒
CN113355416A (zh) * 2021-06-04 2021-09-07 杭州圣庭医疗科技有限公司 一种用于检测胃癌相关基因甲基化的核酸组合物、试剂盒和检测方法

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CN111549129B (zh) * 2020-03-30 2023-08-29 宁波美康盛德医学检验所有限公司 用于检测胃癌的试剂盒及其应用
WO2022035206A1 (ko) * 2020-08-11 2022-02-17 서울대학교병원 Dna 메틸화 수준 검출 제제를 포함하는 위암 예측 또는 진단용 조성물
NL2027228B1 (en) * 2020-12-24 2022-07-20 Stichting Vumc Detection of nucleic acid markers in urine using DNA methylation analysis
CN113234821B (zh) * 2021-04-29 2022-09-16 北京艾克伦医疗科技有限公司 鉴定食管癌状态的方法和试剂盒
CN114574560A (zh) * 2022-04-21 2022-06-03 上海长岛抗体诊断试剂有限公司 一种快速dna亚硫酸盐转化试剂和方法
CN117344010B (zh) * 2022-06-29 2024-04-26 广州市基准医疗有限责任公司 用于诊断胃癌的dna甲基化生物标记物、试剂盒及用途
WO2024001602A1 (zh) * 2022-07-01 2024-01-04 圣湘生物科技股份有限公司 一种用于检测胃癌的组合物,试剂盒及其用途
CN116130000B (zh) * 2022-12-02 2023-12-12 武汉艾米森生命科技有限公司 引物探针序列组合设计方法和装置
CN115976210B (zh) * 2022-12-08 2024-05-28 深圳市晋百慧生物有限公司 用于胃癌诊断和筛查的试剂盒、方法及其用途

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Publication number Priority date Publication date Assignee Title
CN113186282A (zh) * 2021-04-29 2021-07-30 北京艾克伦医疗科技有限公司 鉴定胰腺癌状态的方法和试剂盒
CN113355416A (zh) * 2021-06-04 2021-09-07 杭州圣庭医疗科技有限公司 一种用于检测胃癌相关基因甲基化的核酸组合物、试剂盒和检测方法

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US20210222260A1 (en) 2021-07-22

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Application publication date: 20210326