CN112513099A - 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用 - Google Patents

用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用 Download PDF

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CN112513099A
CN112513099A CN201980051125.8A CN201980051125A CN112513099A CN 112513099 A CN112513099 A CN 112513099A CN 201980051125 A CN201980051125 A CN 201980051125A CN 112513099 A CN112513099 A CN 112513099A
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seq
rharg
polypeptide
abd
arginine
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CN201980051125.8A
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梁润松
沈秀媛
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Chinese University of Hong Kong CUHK
Hong Kong Polytechnic University HKPU
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Chinese University of Hong Kong CUHK
Hong Kong Polytechnic University HKPU
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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CN201980051125.8A 2018-05-31 2019-05-31 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用 Pending CN112513099A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310876042.0A CN116920081A (zh) 2018-05-31 2019-05-31 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用

Applications Claiming Priority (3)

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US201862678300P 2018-05-31 2018-05-31
US62/678,300 2018-05-31
PCT/CN2019/089583 WO2019228510A1 (en) 2018-05-31 2019-05-31 Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities

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CN202310876042.0A Division CN116920081A (zh) 2018-05-31 2019-05-31 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用

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CN202310876042.0A Pending CN116920081A (zh) 2018-05-31 2019-05-31 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用

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US (1) US20200181597A1 (https=)
EP (2) EP4616911A3 (https=)
JP (2) JP7576262B2 (https=)
KR (1) KR20210016434A (https=)
CN (2) CN112513099A (https=)
AU (2) AU2019275733B2 (https=)
BR (1) BR112020024227A2 (https=)
CA (1) CA3101667A1 (https=)
ES (1) ES3049232T3 (https=)
IL (2) IL278993B2 (https=)
SG (1) SG11202011838XA (https=)
TW (2) TWI804691B (https=)
WO (1) WO2019228510A1 (https=)

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AU2019275733B2 (en) * 2018-05-31 2025-07-31 The Chinese University Of Hong Kong Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities
EP3823994A4 (en) * 2018-07-19 2022-04-20 Ab Studio Inc. Novel systems for screening internalizing antibody and uses thereof
WO2020081994A1 (en) 2018-10-19 2020-04-23 Aerase, Inc. Arginine depletion therapy for treatment of gamt deficiency
KR20220082813A (ko) 2019-08-30 2022-06-17 아이글레아 바이오테라퓨틱스, 인크. 인간 재조합 아르기나아제 1의 제조 방법 및 이의 사용
US20210162028A1 (en) * 2019-12-02 2021-06-03 The Hong Kong Polytechnic University Methods for Inducing Intermittent Fasting and Modulating Autophagy
JP7520121B2 (ja) * 2019-12-18 2024-07-22 ヒルズ・ペット・ニュートリシャン・インコーポレーテッド シュウ酸カルシウム結石形成のリスクにあるコンパニオンアニマルを特定する方法、及び当該リスクを減少させるための治療と組成物
JP2023522888A (ja) * 2020-04-17 2023-06-01 バイオ－キャンサー・トリートメント・インターナショナル・リミテッド アルギナーゼを使用してウイルス感染症を処置する方法
WO2021257523A1 (en) * 2020-06-15 2021-12-23 Aeglea Biotherapeutics, Inc. Use of arginase for treatment of influenza infections
WO2022195629A1 (en) * 2021-03-18 2022-09-22 National Institute Of Pharmaceutical Education And Research (Niper) Engineered arginase constructs, method of generation and uses thereof
CN118201954A (zh) * 2021-09-20 2024-06-14 克云生物科技股份公司 精氨酸酶-胰岛素融合蛋白
CN120383669B (zh) * 2025-04-24 2025-10-28 广东医科大学 一种重组人长效白细胞介素-22结合蛋白的制备方法及应用

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