JP2021525749A5 - - Google Patents

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Publication number
JP2021525749A5
JP2021525749A5 JP2020566789A JP2020566789A JP2021525749A5 JP 2021525749 A5 JP2021525749 A5 JP 2021525749A5 JP 2020566789 A JP2020566789 A JP 2020566789A JP 2020566789 A JP2020566789 A JP 2020566789A JP 2021525749 A5 JP2021525749 A5 JP 2021525749A5
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JP
Japan
Prior art keywords
seq
rharg
abd
arginine
abd094
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JP2020566789A
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English (en)
Japanese (ja)
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JP7576262B2 (ja
JP2021525749A (ja
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Priority claimed from PCT/CN2019/089583 external-priority patent/WO2019228510A1/en
Publication of JP2021525749A publication Critical patent/JP2021525749A/ja
Publication of JP2021525749A5 publication Critical patent/JP2021525749A5/ja
Priority to JP2024091527A priority Critical patent/JP2024116237A/ja
Application granted granted Critical
Publication of JP7576262B2 publication Critical patent/JP7576262B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020566789A 2018-05-31 2019-05-31 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用 Active JP7576262B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024091527A JP2024116237A (ja) 2018-05-31 2024-06-05 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862678300P 2018-05-31 2018-05-31
US62/678,300 2018-05-31
PCT/CN2019/089583 WO2019228510A1 (en) 2018-05-31 2019-05-31 Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024091527A Division JP2024116237A (ja) 2018-05-31 2024-06-05 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用

Publications (3)

Publication Number Publication Date
JP2021525749A JP2021525749A (ja) 2021-09-27
JP2021525749A5 true JP2021525749A5 (https=) 2022-07-19
JP7576262B2 JP7576262B2 (ja) 2024-10-31

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ID=68697862

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020566789A Active JP7576262B2 (ja) 2018-05-31 2019-05-31 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用
JP2024091527A Pending JP2024116237A (ja) 2018-05-31 2024-06-05 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用

Family Applications After (1)

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JP2024091527A Pending JP2024116237A (ja) 2018-05-31 2024-06-05 癌、肥満、代謝障害及び関連する合併症と併存症のためのアルギニン枯渇剤の組成と応用

Country Status (13)

Country Link
US (1) US20200181597A1 (https=)
EP (2) EP4616911A3 (https=)
JP (2) JP7576262B2 (https=)
KR (1) KR20210016434A (https=)
CN (2) CN112513099A (https=)
AU (2) AU2019275733B2 (https=)
BR (1) BR112020024227A2 (https=)
CA (1) CA3101667A1 (https=)
ES (1) ES3049232T3 (https=)
IL (2) IL278993B2 (https=)
SG (1) SG11202011838XA (https=)
TW (2) TWI804691B (https=)
WO (1) WO2019228510A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12508306B2 (en) 2018-04-25 2025-12-30 Washington University Compositions and methods of use thereof for treatment of metabolic diseases and related disorders
AU2019275733B2 (en) * 2018-05-31 2025-07-31 The Chinese University Of Hong Kong Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities
EP3823994A4 (en) * 2018-07-19 2022-04-20 Ab Studio Inc. Novel systems for screening internalizing antibody and uses thereof
WO2020081994A1 (en) 2018-10-19 2020-04-23 Aerase, Inc. Arginine depletion therapy for treatment of gamt deficiency
KR20220082813A (ko) 2019-08-30 2022-06-17 아이글레아 바이오테라퓨틱스, 인크. 인간 재조합 아르기나아제 1의 제조 방법 및 이의 사용
US20210162028A1 (en) * 2019-12-02 2021-06-03 The Hong Kong Polytechnic University Methods for Inducing Intermittent Fasting and Modulating Autophagy
JP7520121B2 (ja) * 2019-12-18 2024-07-22 ヒルズ・ペット・ニュートリシャン・インコーポレーテッド シュウ酸カルシウム結石形成のリスクにあるコンパニオンアニマルを特定する方法、及び当該リスクを減少させるための治療と組成物
JP2023522888A (ja) * 2020-04-17 2023-06-01 バイオ-キャンサー・トリートメント・インターナショナル・リミテッド アルギナーゼを使用してウイルス感染症を処置する方法
WO2021257523A1 (en) * 2020-06-15 2021-12-23 Aeglea Biotherapeutics, Inc. Use of arginase for treatment of influenza infections
WO2022195629A1 (en) * 2021-03-18 2022-09-22 National Institute Of Pharmaceutical Education And Research (Niper) Engineered arginase constructs, method of generation and uses thereof
CN118201954A (zh) * 2021-09-20 2024-06-14 克云生物科技股份公司 精氨酸酶-胰岛素融合蛋白
CN120383669B (zh) * 2025-04-24 2025-10-28 广东医科大学 一种重组人长效白细胞介素-22结合蛋白的制备方法及应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196195A (en) * 1990-03-27 1993-03-23 Cornell Research Foundation, Inc. Use of arginase to control nitric oxide formation
AU5192498A (en) * 1996-12-03 1998-06-29 Kyowa Hakko Kogyo Co. Ltd. Tissue fibrosis inhibitor
US6183738B1 (en) * 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase
WO2002009741A1 (en) * 2000-07-27 2002-02-07 Angiolab, Inc. The pharmaceutical composition comprising arginine deiminase for inhibiting angiogenesis
HK1053577A2 (en) * 2002-06-20 2003-10-10 Bio-Cancer Treatment International Limited Pharmaceutical composition and method of treatment of human malignanices with arginine deprivation
JP2005538709A (ja) * 2002-06-20 2005-12-22 バイオ−キャンサー・トリートメント・インターナショナル・リミテッド アルギニンを欠乏させることによってヒト悪性腫瘍を治療する医薬品及び方法
EP1667724A2 (en) * 2003-09-19 2006-06-14 Novo Nordisk A/S Albumin-binding derivatives of therapeutic peptides
BR122019021416A2 (https=) * 2003-09-19 2019-12-21
US7670595B2 (en) 2004-06-28 2010-03-02 Merck Patent Gmbh Fc-interferon-beta fusion proteins
WO2006125632A2 (en) * 2005-05-24 2006-11-30 Rechtsanwalt Dr. Martin Prager Als Insolvenzverwalter Über Das Vermögen Der Xantos Biomedicine Ag, Pluta Rechtsanwalts Gmbh Agonistic antibodies that bind to the tweak receptor fn14 and thereby modulate adiposity-associated phenotypes as well as their use in therapy
CA2742497C (en) 2008-10-31 2024-01-23 George Georgiou Compositions of engineered human arginases and methods for treating cancer
DK2786762T3 (da) * 2008-12-19 2019-05-06 Macrogenics Inc Kovalente diabodies og anvendelser deraf
AU2010242422B2 (en) * 2009-03-26 2014-12-04 The Hong Kong Polytechnic University Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents
WO2011008495A2 (en) * 2009-06-29 2011-01-20 The Board Of Regents Of The University Of Texas System Arginase formulations and methods
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
CN106456723B (zh) 2014-04-29 2021-03-09 康达医药科技有限公司 采用精氨酸酶i调节免疫系统的方法和组合物
WO2015177175A2 (en) * 2014-05-22 2015-11-26 Pieris Ag Novel specific-binding polypeptides and uses thereof
WO2016044656A1 (en) * 2014-09-17 2016-03-24 Ansun Biopharma, Inc. Treatment of infection by human enterovirus d68
MX2018013546A (es) * 2016-05-06 2019-04-22 Phasebio Pharmaceuticals Inc Proteinas de fusion de elp para liberacion controlada y sostenida.
US12508306B2 (en) * 2018-04-25 2025-12-30 Washington University Compositions and methods of use thereof for treatment of metabolic diseases and related disorders
AU2019275733B2 (en) * 2018-05-31 2025-07-31 The Chinese University Of Hong Kong Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities
WO2020081994A1 (en) * 2018-10-19 2020-04-23 Aerase, Inc. Arginine depletion therapy for treatment of gamt deficiency

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