CN112438941A - Allergy-relieving repair composition and skin care product containing same - Google Patents
Allergy-relieving repair composition and skin care product containing same Download PDFInfo
- Publication number
- CN112438941A CN112438941A CN202011631173.5A CN202011631173A CN112438941A CN 112438941 A CN112438941 A CN 112438941A CN 202011631173 A CN202011631173 A CN 202011631173A CN 112438941 A CN112438941 A CN 112438941A
- Authority
- CN
- China
- Prior art keywords
- allergy
- relieving
- repair composition
- following components
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract description 69
- 208000026935 allergic disease Diseases 0.000 title claims abstract description 69
- 230000008439 repair process Effects 0.000 title claims abstract description 69
- 239000000203 mixture Substances 0.000 title claims abstract description 53
- 239000006166 lysate Substances 0.000 claims abstract description 22
- 238000000855 fermentation Methods 0.000 claims abstract description 21
- 230000004151 fermentation Effects 0.000 claims abstract description 21
- 239000000284 extract Substances 0.000 claims abstract description 16
- 239000000839 emulsion Substances 0.000 claims abstract description 15
- 241000196324 Embryophyta Species 0.000 claims abstract description 14
- 241000186660 Lactobacillus Species 0.000 claims abstract description 11
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 11
- 235000013406 prebiotics Nutrition 0.000 claims abstract description 11
- 229940116815 crocus sativus flower extract Drugs 0.000 claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 9
- 238000003756 stirring Methods 0.000 claims description 33
- 239000003974 emollient agent Substances 0.000 claims description 18
- 239000003906 humectant Substances 0.000 claims description 18
- 239000002562 thickening agent Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 238000010438 heat treatment Methods 0.000 claims description 12
- 239000003755 preservative agent Substances 0.000 claims description 12
- 230000002335 preservative effect Effects 0.000 claims description 12
- 239000003995 emulsifying agent Substances 0.000 claims description 10
- YPFDHNVEDLHUCE-UHFFFAOYSA-N propane-1,3-diol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims description 10
- 230000007815 allergy Effects 0.000 claims description 9
- 239000002738 chelating agent Substances 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- 241000235346 Schizosaccharomyces Species 0.000 claims description 8
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 8
- 235000020971 citrus fruits Nutrition 0.000 claims description 8
- 239000003921 oil Substances 0.000 claims description 8
- 235000019198 oils Nutrition 0.000 claims description 8
- -1 polydimethylsiloxane Polymers 0.000 claims description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 6
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims description 6
- 229920002125 Sokalan® Polymers 0.000 claims description 6
- 229960001631 carbomer Drugs 0.000 claims description 6
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 6
- 238000007599 discharging Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 6
- 238000005086 pumping Methods 0.000 claims description 6
- 240000002989 Euphorbia neriifolia Species 0.000 claims description 5
- 239000010487 meadowfoam seed oil Substances 0.000 claims description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- 230000002421 anti-septic effect Effects 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims description 3
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims description 3
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical group CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 claims description 3
- 229920002498 Beta-glucan Polymers 0.000 claims description 3
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 3
- 239000004386 Erythritol Substances 0.000 claims description 3
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims description 3
- 240000004534 Scutellaria baicalensis Species 0.000 claims description 3
- 235000017089 Scutellaria baicalensis Nutrition 0.000 claims description 3
- 244000044822 Simmondsia californica Species 0.000 claims description 3
- 235000019414 erythritol Nutrition 0.000 claims description 3
- 229940009714 erythritol Drugs 0.000 claims description 3
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims description 3
- XJNUECKWDBNFJV-UHFFFAOYSA-N hexadecyl 2-ethylhexanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)C(CC)CCCC XJNUECKWDBNFJV-UHFFFAOYSA-N 0.000 claims description 3
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims description 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 3
- 235000019719 rose oil Nutrition 0.000 claims description 3
- 239000010666 rose oil Substances 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 229940084750 sophora flavescens root extract Drugs 0.000 claims description 3
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims description 3
- 229960000281 trometamol Drugs 0.000 claims description 3
- 244000125300 Argania sideroxylon Species 0.000 claims description 2
- 235000016108 Argania sideroxylon Nutrition 0.000 claims description 2
- 240000007436 Cananga odorata Species 0.000 claims description 2
- 241000675108 Citrus tangerina Species 0.000 claims description 2
- 241000208152 Geranium Species 0.000 claims description 2
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims description 2
- 235000019486 Sunflower oil Nutrition 0.000 claims description 2
- 229960004308 acetylcysteine Drugs 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 229940084760 glycyrrhiza inflata root extract Drugs 0.000 claims description 2
- 239000002600 sunflower oil Substances 0.000 claims description 2
- 229940042585 tocopherol acetate Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract description 4
- 235000013399 edible fruits Nutrition 0.000 abstract description 2
- 230000008961 swelling Effects 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000023753 dehiscence Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 21
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 8
- 239000002537 cosmetic Substances 0.000 description 6
- 241000221095 Simmondsia Species 0.000 description 5
- 230000003796 beauty Effects 0.000 description 5
- 238000011156 evaluation Methods 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 4
- 235000014655 lactic acid Nutrition 0.000 description 4
- 239000004310 lactic acid Substances 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 3
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 description 2
- 229940035437 1,3-propanediol Drugs 0.000 description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 2
- 229920000166 polytrimethylene carbonate Polymers 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000000811 xylitol Substances 0.000 description 2
- 235000010447 xylitol Nutrition 0.000 description 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 2
- 229960002675 xylitol Drugs 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- KZVAAIRBJJYZOW-VPENINKCSA-N (2r,3r,4s)-2-(hydroxymethyl)oxolane-3,4-diol Chemical compound OC[C@H]1OC[C@H](O)[C@H]1O KZVAAIRBJJYZOW-VPENINKCSA-N 0.000 description 1
- 229940015975 1,2-hexanediol Drugs 0.000 description 1
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- NLMKTBGFQGKQEV-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO NLMKTBGFQGKQEV-UHFFFAOYSA-N 0.000 description 1
- ICIDSZQHPUZUHC-UHFFFAOYSA-N 2-octadecoxyethanol Chemical compound CCCCCCCCCCCCCCCCCCOCCO ICIDSZQHPUZUHC-UHFFFAOYSA-N 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- 241001632409 Aralia elata Species 0.000 description 1
- 235000015888 Aralia elata Nutrition 0.000 description 1
- PGLIUCLTXOYQMV-UHFFFAOYSA-N Cetirizine hydrochloride Chemical compound Cl.Cl.C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 PGLIUCLTXOYQMV-UHFFFAOYSA-N 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 241000202807 Glycyrrhiza Species 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 108010020346 Polyglutamic Acid Proteins 0.000 description 1
- 241001531051 Potentilla chinensis Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 229920002197 Sodium polyaspartate Polymers 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 229940083987 anhydroxylitol Drugs 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000003651 basophil Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 1
- 239000001409 cananga odorata hook. f. and thomas. flower oil Substances 0.000 description 1
- 229940056318 ceteth-20 Drugs 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- XJFGDLJQUJQUEI-UHFFFAOYSA-N dodecyl decanoate dodecyl octanoate Chemical compound CCCCCCCCCCCCOC(=O)CCCCCCC.CCCCCCCCCCCCOC(=O)CCCCCCCCC XJFGDLJQUJQUEI-UHFFFAOYSA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229920000370 gamma-poly(glutamate) polymer Polymers 0.000 description 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 description 1
- 235000019717 geranium oil Nutrition 0.000 description 1
- 239000010648 geranium oil Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 229940075529 glyceryl stearate Drugs 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- LTINPJMVDKPJJI-UHFFFAOYSA-N iodinated glycerol Chemical compound CC(I)C1OCC(CO)O1 LTINPJMVDKPJJI-UHFFFAOYSA-N 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 235000011477 liquorice Nutrition 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 239000002884 skin cream Substances 0.000 description 1
- 229940047670 sodium acrylate Drugs 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 229940114926 stearate Drugs 0.000 description 1
- 229940100459 steareth-20 Drugs 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a allergy-relieving repair composition, which consists of prebiotics, a plant allergy-relieving agent SGS, an orange fruit extract and a crocus sativus flower extract, wherein the prebiotics consist of a yeast dehiscence lysate and a lactobacillus fermentation lysate, and further discloses a specific formula containing essence and emulsion containing the allergy-relieving repair composition and a preparation method thereof. The product prepared by the formula has stable viscosity at 4 ℃ and 45 ℃; no layering occurs for more than 1 month; has the effects of inhibiting inflammation, effectively relieving skin, and relieving skin inflammation symptoms such as heat red swelling.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a allergy-relieving repair composition and a skin care product containing the same.
Background
With the continuous improvement of living standard, the requirements of people on beauty and skin care cosmetics are higher and higher, the quality of the cosmetics in the market is uneven, and many products cannot play the role of maintenance and are easy to cause allergy. The allergy is mainly that a human body generates a large amount of free radicals in the body under the stimulation of environmental factors such as chemical substances, air pollution, solar radiation and the like, the free radicals cannot be removed in time after being oxidized, cell membranes of mast cells and basophils can be damaged, the cell membranes cause cell instability, and at the moment, cells release allergic media to cause allergy.
People who love beauty have the beauty, and people have continuous pursuit for beautifying cosmetics. With the improvement of living standard and the enhancement of beauty awareness, cosmetics have wide popularization range, people not only pursue beauty of skin surface, but also pay more attention to the internal care of skin, such as repair and allergy relief. In recent years, prebiotics are well applied to cosmetics and have an obvious effect on the balance of skin micro-ecology; and Chinese herbal medicines play an important role in the fields of our lives and medicines since ancient times in China, our country is wide, and the types of the Chinese herbal medicines are many, so that a product combining the effects of prebiotics and the Chinese herbal medicines is researched and developed, and the most appropriate combination is selected, so that the effects of better maintaining the micro-ecology of the skin, relieving the skin sensitivity and repairing the damaged skin are achieved.
Disclosure of Invention
Aiming at the problems in the prior art, the invention aims to provide a allergy-relieving repair composition and a skin care product containing the same.
The invention is realized by the following technical scheme:
the allergy-relieving repair composition is characterized by comprising prebiotics, a plant allergy-relieving agent SGS, a citrus fruit extract and a crocus sativus flower extract, wherein the prebiotics comprise a schizosaccharomyces cerevisiae fermentation product lysate and a lactobacillus fermentation lysate.
The allergy-relieving repair composition is characterized in that the main active components of the plant allergy-relieving agent SGS are a scutellaria baicalensis root extract, a sophora flavescens root extract and a glycyrrhiza inflata root extract.
The skin care product containing the allergy-relieving repair composition is characterized in that the skin care product is allergy-relieving repair essence, and each 100g of the allergy-relieving repair essence comprises the following components in parts by weight: 12.4g of humectant, 0.5g of thickening agent, 0.71g of emollient, 0.6g of preservative, 8.5g of allergy-relieving repair composition and the balance of water.
The skin care product containing the allergy-relieving repair composition is characterized in that:
the humectant consists of the following components in parts by weight: 6g of 1, 3-propylene glycol, 2g of super PGA, 1.5g of Aquaxyl, SPA-251 g, 0.5g of bis-PEG-15 methyl ether polydimethylsiloxane, 0.6g of erythritol, 0.3g of acetylcysteine and 0.5g of oat beta-glucan;
the thickening agent consists of the following components in parts by weight: 0.2g of carbomer sodium and 0.3g of lecigel;
the emollient consists of the following components in parts by weight: 0.2g of tangerine peel oil, 0.2g of argania spinosa kernel oil, 0.2g of meadowfoam seed oil, 0.3g of rose oil, 0.03g of ylang-ylang oil and 0.02g of geranium sunflower oil;
the allergy-relieving repair composition comprises the following components in parts by weight: 3g of schizosaccharomyces cerevisiae fermentation product lysate, 2.5g of lactobacillus fermentation lysate, 1g of plant sensitizer SGS, 1g of citrus fruit extract and 1g of crocus sativus flower extract;
the antiseptic is PHG produced by THOR, and the dosage is 0.6 g.
The repair essence containing the allergy-relieving repair composition is characterized by being prepared by the following method:
1) adding water, humectant and thickener into main pot, heating to 82-85 deg.C, homogenizing for 3-5min, stirring, and keeping the temperature for 30 min;
2) adding the emollient of formula amount into a phase pan, heating to 82-85 deg.C, stirring, and keeping the temperature for use;
3) pumping the material body in the phase pan into the main pan, homogenizing for 8-10min, stirring uniformly, and cooling;
4) cooling to below 45 ℃, adding the preservative with the formula amount, and uniformly stirring;
5) finally, adding the allergy-relieving repair composition in the formula amount, uniformly stirring, completely defoaming, and discharging by 200 meshes to obtain the repair essence containing the allergy-relieving repair composition.
The skin care product containing the allergy relieving and repairing composition is characterized in that the skin care product is allergy relieving and repairing emulsion, and every 100g of the allergy relieving and repairing emulsion comprises the following components in parts by weight: 9.3g of humectant, 0.6g of thickener, 0.03g of chelating agent, 2g of emulsifier, 10g of emollient, 0.6g of preservative, 0.2g of pH regulator, 8g of allergy-relieving repair composition and the balance of water.
The skin care product containing the allergy-relieving repair composition is characterized in that:
the humectant consists of the following components in parts by weight: 6g of 1, 3-propylene glycol, 1g of 1, 2-pentanediol, 2g of bis-PEG-15 methyl ether polydimethylsiloxane and 250.3 g of SPA;
the thickener consists of 0.4g of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and 0.2g of carbomer;
the emollient consists of the following components in parts by weight: 2g of meadowfoam seed oil, 1.5g of DW Jojoba Colorless, 1.5g of pentaerythritol tetraester, 3.5g of cetyl ethylhexanoate, 0.5g of tocopherol acetate and 1g of Vegelight 1214 LC;
the chelating agent is EDTA disodium;
the emulsifier is EMULIUM DELTA produced by Gattefose;
the antiseptic is PHG produced by THOR, and the dosage is 0.6 g;
tromethamine is selected as the PH regulator;
the allergy-relieving repair composition comprises the following components in parts by weight: 3g of schizosaccharomyces cerevisiae fermentation product lysate, 2.5g of lactobacillus fermentation lysate, 1g of plant sensitizer SGS, 1g of citrus fruit extract and 1g of crocus sativus flower extract.
The repairing emulsion containing the allergy-relieving repairing composition is characterized by being prepared by the following method:
1) adding water, humectant, thickener and chelating agent into main pot, heating to 82-85 deg.C, homogenizing for 3-5min, stirring, and keeping the temperature for 30 min;
2) adding the emulsifier and the emollient with the formula ratio into a phase pot, heating to 82-85 ℃, uniformly stirring, and keeping the temperature for later use;
3) pumping the material body in the phase pan into the main pan, homogenizing for 8-10min, stirring uniformly, and cooling;
4) adding the pH regulator with the formula amount into a main pot by using a water solvent, and uniformly stirring;
5) when the temperature of the material body in the main pot is reduced to below 45 ℃, adding the preservative with the formula amount, and uniformly stirring;
6) finally, adding the allergy-relieving repair composition with the formula amount, uniformly stirring, completely defoaming, and discharging by 200 meshes to obtain the repair emulsion containing the allergy-relieving repair composition.
Compared with the prior art, the invention has the following beneficial effects:
1) by combining prebiotics and Chinese herbal medicine extracts, the skin care product prepared by using the lysate of the yeast bifida fermentation product, the lysate of the lactobacillus fermentation and the plant extract as main raw materials can repair damaged stratum corneum, nerve fiber and endothelial cells of vessel walls, has an antioxidation effect, accelerates the cyclic metabolism and removes accumulated toxins; the effective components cooperate with each other, so that the immunity of the damaged skin can be enhanced, and the sensitivity of the skin can be improved;
2) the skin cream is prepared by carefully selecting an emulsifier, grease and an efficacy active substance, and has refreshing and moisturizing skin feeling and excellent skin barrier repairing efficacy;
3) by adding typical anti-inflammatory plant active ingredients containing radix sophorae flavescentis, liquorice and radix scutellariae, the release of inflammatory factors can be effectively inhibited, cells are protected from being damaged by the outside, and simultaneously, the cutin barrier is reinforced, so that the skin is helped to relieve symptoms such as fever, redness, burning pain and swelling.
Detailed Description
The present invention will be described in further detail with reference to specific examples to better understand the technical solution.
The allergy-relieving repair composition comprises prebiotics, a plant allergy-relieving agent SGS, an orange fruit extract and a crocus sativus flower extract, wherein the prebiotics comprise a yeast lysate of a yeast fermentation product and a lactobacillus fermentation lysate, the plant allergy-relieving agent SGS is purchased from GREAF, and the main active components are a scutellaria baicalensis root extract, a sophora flavescens root extract and a glycyrrhiza inflate root extract.
Example 1: repair essence containing allergy-relieving repair composition
Every 100g of the allergy-relieving repair essence consists of the following formula by weight: 12.4g of humectant, 0.5g of thickening agent, 0.71g of emollient, 0.6g of preservative, 8.5g of allergy-relieving repair composition and the balance of water.
Wherein the humectant consists of 6g of 1, 3-propanediol, 2g of super PGA, 1.5g of Aquaxyl, 1g of SPA-25, 0.5g of bis-PEG-15 methyl ether polydimethylsiloxane, 0.6g of erythritol, 0.3g of acetyl chitosamine and 0.5g of oat beta-glucan; the thickener consists of 0.2g of sodium carbomer and 0.3g of lecigel; the emollient is composed of 0.2g of peel oil of fructus Citri Tangerinae, 0.2g of Aralia mandshurica kernel oil, 0.2g of white Potentilla chinensis seed oil, 0.3g of rose oil, 0.03g of ylang-ylang flower oil and 0.02g of geranium oil; the allergy-relieving repair composition comprises 3g of a schizosaccharomyces cerevisiae fermentation product lysate, 2.5g of a lactobacillus fermentation lysate, 1g of a plant allergy-relieving agent SGS, 1g of a citrus fruit extract and 1g of a crocus sativus flower extract.
The repair essence containing the allergy-relieving repair composition is prepared by the following method:
1) adding water, humectant and thickener into main pot, heating to 82-85 deg.C, homogenizing for 3-5min, stirring, and keeping the temperature for 30 min; 2) adding the emollient of formula amount into a phase pan, heating to 82-85 deg.C, stirring, and keeping the temperature for use; 3) pumping the material body in the phase pan into the main pan, homogenizing for 8-10min, stirring uniformly, and cooling; 4) cooling to below 45 ℃, adding the preservative with the formula amount, and uniformly stirring; 5) finally, adding the allergy-relieving repair composition in the formula amount, uniformly stirring, completely defoaming, and discharging by 200 meshes to obtain the repair essence containing the allergy-relieving repair composition.
Test example: selecting 50 sensitive subjects, smearing a certain amount of stimulant to cheeks and nasolabial folds, carrying out lactic acid sting evaluation on the subjects, smearing the products prepared in the embodiment once in the morning and evening, and then carrying out lactic acid sting evaluation on the 7 th day, wherein the results show that the parts smeared with the essence of the embodiment basically have no sting, and the parts not smeared have obvious sting.
Example 2: repair emulsions containing a soothing repair composition
Every 100g of the allergy-relieving repair emulsion comprises the following components in parts by weight: 9.3g of humectant, 0.6g of thickener, 0.03g of chelating agent, 2g of emulsifier, 10g of emollient, 0.6g of preservative, 0.2g of pH regulator, 8g of allergy-relieving repair composition and the balance of water.
The humectant consists of the following components in parts by weight: 6g of 1, 3-propanediol, 1g of 1, 2-pentanediol, 2g of bis-PEG-15 methyl ether polydimethylsiloxane, and 0.3g of SPA-25; the thickener consists of 0.4g of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and 0.2g of carbomer; the emollient consisted of 2g of meadowfoam seed oil, 1.5g of DW Jojoba Colorless, 1.5g of pentaerythritol tetraester, 3.5g of cetyl ethylhexanoate, 0.5g of tocopheryl acetate, 1g of Vegelight 1214 LC; the chelating agent is EDTA disodium; tromethamine is selected as the PH regulator; the emulsifier is EMULIUM DELTA produced by Gattefose; the allergy-relieving repair composition comprises 3g of a schizosaccharomyces cerevisiae fermentation product lysate, 2.5g of a lactobacillus fermentation lysate, 1g of a plant allergy-relieving agent SGS, 1g of a citrus fruit extract and 1g of a crocus sativus flower extract.
The repair emulsion containing the allergy-relieving repair composition is prepared by the following method: 1) adding water, humectant, thickener and chelating agent into main pot, heating to 82-85 deg.C, homogenizing for 3-5min, stirring, and keeping the temperature for 30 min; 2) adding the emulsifier and the emollient with the formula ratio into a phase pot, heating to 82-85 ℃, uniformly stirring, and keeping the temperature for later use; 3) pumping the material body in the phase pan into the main pan, homogenizing for 8-10min, stirring uniformly, and cooling; 4) adding the pH regulator with the formula amount into a main pot by using a water solvent, and uniformly stirring; 5) when the temperature of the material body in the main pot is reduced to below 45 ℃, adding the preservative with the formula amount, and uniformly stirring; 6) finally, adding the allergy-relieving repair composition with the formula amount, uniformly stirring, completely defoaming, and discharging by 200 meshes to obtain the repair emulsion containing the allergy-relieving repair composition.
Test example: selecting 50 sensitive subjects, applying a certain amount of stimulus to the cheeks and the nasolabial folds, carrying out lactic acid sting evaluation on the subjects, applying the prepared products of the embodiment once in the morning and evening, and then carrying out lactic acid sting evaluation on the 7 th day, wherein the results show that the parts applied with the emulsion of the embodiment have no pricking feeling basically, and the parts not applied with the emulsion have obvious pricking feeling.
In the stability test, the two examples have the effect that the viscosity is stable under the temperature conditions of 4 ℃ and 45 ℃ and the delamination is avoided for more than 1 month.
In the above example formulations: super PGA, available from vedan, is a combination of sodium polyglutamate and butylene glycol; aquaxyl is available from seppic and is a combination of xylitol-based glucoside, anhydroxylitol, xylitol, water, glucose; SPA-25, purchased from Beijing, Yanzhishan, is a combination of sodium polyaspartate, butanediol, 1, 2-hexanediol, and water; lecigel is available from LUCAS and is a combination of sodium acrylate copolymer and lecithin; PHG is available from THOR, and is a combination of phenoxyethanol and caprylyl glycol; emulium DELTA is available from Gattefose as a combination of cetyl alcohol, glyceryl stearate, PEG-75 stearate, ceteth-20 and steareth-20; DW Jojoba Colorless, available from Vantage, is a mixture of Jojoba (SIMMONDSIA CHINENSIS) seed oil and Jojoba (SIMMONDSIA CHINENSIS) seed extract; vegelight 1214 LC was purchased from BioSynthis as a combination of C9-12 alkane and coco caprylate/caprate.
The optimal ratio is given in the above embodiments, and the adjustment of the upper and lower ranges based on the ratio of the present invention is within the scope of the present invention.
Claims (8)
1. The allergy-relieving repair composition is characterized by comprising prebiotics, a plant allergy-relieving agent SGS, a citrus fruit extract and a crocus sativus flower extract, wherein the prebiotics comprise a schizosaccharomyces cerevisiae fermentation product lysate and a lactobacillus fermentation lysate.
2. The allergy-relieving repair composition of claim 1, wherein the plant allergy-relieving agent SGS comprises as major active ingredients a Scutellaria baicalensis root extract, a Sophora flavescens root extract and a Glycyrrhiza inflata root extract.
3. The skin care product containing the allergy-relieving repair composition is characterized by being allergy-relieving repair essence, wherein each 100g of the allergy-relieving repair essence comprises the following components in parts by weight: 12.4g of humectant, 0.5g of thickening agent, 0.71g of emollient, 0.6g of preservative, 8.5g of allergy-relieving repair composition and the balance of water.
4. A skin care product comprising a soothing repair composition according to claim 3 wherein:
the humectant consists of the following components in parts by weight: 6g of 1, 3-propylene glycol, 2g of super PGA, 1.5g of Aquaxyl, SPA-251 g, 0.5g of bis-PEG-15 methyl ether polydimethylsiloxane, 0.6g of erythritol, 0.3g of acetylcysteine and 0.5g of oat beta-glucan;
the thickening agent consists of the following components in parts by weight: 0.2g of carbomer sodium and 0.3g of lecigel;
the emollient consists of the following components in parts by weight: 0.2g of tangerine peel oil, 0.2g of argania spinosa kernel oil, 0.2g of meadowfoam seed oil, 0.3g of rose oil, 0.03g of ylang-ylang oil and 0.02g of geranium sunflower oil;
the allergy-relieving repair composition comprises the following components in parts by weight: 3g of schizosaccharomyces cerevisiae fermentation product lysate, 2.5g of lactobacillus fermentation lysate, 1g of plant sensitizer SGS, 1g of citrus fruit extract and 1g of crocus sativus flower extract;
the antiseptic is PHG produced by THOR, and the dosage is 0.6 g.
5. The repair essence containing the allergy-relieving repair composition is characterized by being prepared by the following method:
1) adding water, humectant and thickener into main pot, heating to 82-85 deg.C, homogenizing for 3-5min, stirring, and keeping the temperature for 30 min;
2) adding the emollient of formula amount into a phase pan, heating to 82-85 deg.C, stirring, and keeping the temperature for use;
3) pumping the material body in the phase pan into the main pan, homogenizing for 8-10min, stirring uniformly, and cooling;
4) cooling to below 45 ℃, adding the preservative with the formula amount, and uniformly stirring;
5) finally, adding the allergy-relieving repair composition in the formula amount, uniformly stirring, completely defoaming, and discharging by 200 meshes to obtain the repair essence containing the allergy-relieving repair composition.
6. The skin care product containing the allergy relieving and repairing composition is characterized in that the skin care product is allergy relieving and repairing emulsion, and each 100g of the allergy relieving and repairing emulsion comprises the following components in parts by weight: 9.3g of humectant, 0.6g of thickener, 0.03g of chelating agent, 2g of emulsifier, 10g of emollient, 0.6g of preservative, 0.2g of pH regulator, 8g of allergy-relieving repair composition and the balance of water.
7. A skin care product comprising a soothing repair composition according to claim 6 wherein:
the humectant consists of the following components in parts by weight: 6g of 1, 3-propylene glycol, 1g of 1, 2-pentanediol, 2g of bis-PEG-15 methyl ether polydimethylsiloxane and 250.3 g of SPA;
the thickener consists of 0.4g of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and 0.2g of carbomer;
the emollient consists of the following components in parts by weight: 2g of meadowfoam seed oil, 1.5g of DW Jojoba Colorless, 1.5g of pentaerythritol tetraester, 3.5g of cetyl ethylhexanoate, 0.5g of tocopherol acetate and 1g of Vegelight 1214 LC;
the chelating agent is EDTA disodium;
the emulsifier is EMULIUM DELTA produced by Gattefose;
the antiseptic is PHG produced by THOR, and the dosage is 0.6 g;
tromethamine is selected as the PH regulator;
the allergy-relieving repair composition comprises the following components in parts by weight: 3g of schizosaccharomyces cerevisiae fermentation product lysate, 2.5g of lactobacillus fermentation lysate, 1g of plant sensitizer SGS, 1g of citrus fruit extract and 1g of crocus sativus flower extract.
8. A repair emulsion comprising a soothing repair composition, characterized in that it is prepared by the following method:
1) adding water, humectant, thickener and chelating agent into main pot, heating to 82-85 deg.C, homogenizing for 3-5min, stirring, and keeping the temperature for 30 min;
2) adding the emulsifier and the emollient with the formula ratio into a phase pot, heating to 82-85 ℃, uniformly stirring, and keeping the temperature for later use;
3) pumping the material body in the phase pan into the main pan, homogenizing for 8-10min, stirring uniformly, and cooling;
4) adding the pH regulator with the formula amount into a main pot by using a water solvent, and uniformly stirring;
5) when the temperature of the material body in the main pot is reduced to below 45 ℃, adding the preservative with the formula amount, and uniformly stirring;
6) finally, adding the allergy-relieving repair composition with the formula amount, uniformly stirring, completely defoaming, and discharging by 200 meshes to obtain the repair emulsion containing the allergy-relieving repair composition.
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