CN112438915B - Skin care composition, cosmetic and method for producing same - Google Patents

Skin care composition, cosmetic and method for producing same Download PDF

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CN112438915B
CN112438915B CN201910802574.3A CN201910802574A CN112438915B CN 112438915 B CN112438915 B CN 112438915B CN 201910802574 A CN201910802574 A CN 201910802574A CN 112438915 B CN112438915 B CN 112438915B
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杨振艳
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Guangzhou Nanfang Yikang Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

The invention provides a skin care composition, which comprises magnolia bark extract, red sage root extract and tree peony bark extract, is applied to cosmetics in proper proportion, has the skin care effects of whitening, acne removing and acne mark removing, and has good inhibition effects on itching and inflammation.

Description

Skin care composition, cosmetic and method for producing same
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to a skin care composition, a cosmetic and a preparation method thereof.
Background
Exposure of facial skin to air for a long period of time causes ultraviolet radiation, and harmful substances such as dirt, dust, bacteria, etc., floating in the air irritate the skin surface. In addition, the oil, sweat, dead cells and the like secreted by the skin can influence the normal function of the skin, even cause skin disease infection, cause skin diseases such as acne and the like, and cause skin melanin deposition and premature aging.
The cosmetics with the effects of whitening, acne removing, acne mark removing, skin wound repairing, skin itching and inflammation inhibiting and the like on the current market have difficulty in considering various skin repairing functions, and have common effects and high cost.
Disclosure of Invention
The invention aims to provide a skin care composition, a cosmetic and a preparation method thereof, which have the effects of whitening, acne removing or acne mark removing, repairing skin wounds, inhibiting skin itching, inflammation and the like.
The specific technical scheme is as follows:
a skin care composition comprising: magnolia bark extract, red sage extract and tree peony bark extract;
the mass ratio of the magnolia bark extract, the red sage root extract and the tree peony bark extract is (0.2-0.4) to 4 (0.2-0.4).
The invention also provides application of the skin care composition, and the specific technical scheme is as follows:
use of a skin care composition as described above in the preparation of a cosmetic.
The invention also provides a skin care cosmetic, which has the following specific technical scheme:
a skin care cosmetic comprising a skin care composition as described above and cosmetically acceptable adjuvants.
The invention also provides a preparation method of the skin care cosmetic, which comprises the following steps:
a method for preparing a skin care cosmetic comprising the steps of:
1) Mixing tocopheryl acetate, cetostearyl alcohol, pentaerythritol distearate, phytosterol esters, glycerol tri (ethylhexanoate), polydimethylsiloxane, hydrogenated polydecene, cortex magnoliae officinalis bark extract, cetostearyl alcohol and cetostearyl glucoside, glycerol stearate and PEG-100 stearate, and dissolving under heating for later use;
2) Mixing pure water, carbomer, allantoin, sodium hyaluronate, glycerol and propylene glycol, homogenizing, dispersing, and heating for dissolving;
3) Adding the product of the step 2) and the product of the step 1) into an emulsifying pot for mixing, vacuumizing, homogenizing and dispersing;
4) Adding sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80 phase and Saviae Miltiorrhizae radix extract into the product of step 3), and cooling;
5) Heating and dissolving cortex moutan extract and ethanol together, and mixing with the product of step 4);
6) Adding phenoxyethanol, ethylhexyl glycerol and essence, stirring uniformly, and mixing with the product of the step 5); then adding the aminomethyl propanol solution, and homogenizing and uniformly mixing.
Based on the technical scheme, the invention has the following beneficial effects:
through a great deal of creative labor of the inventor, the invention discovers that the magnolia bark extract, the red sage root extract and the tree peony bark extract are reasonably matched in a proper proportion, on one hand, the composition has remarkable inhibition effect on skin inflammation, is beneficial to accelerating skin metabolism, has skin care effects of whitening, acne removing and acne mark removing, and has good inhibition effect on itching and inflammation when being applied to cosmetics. Wherein, the magnolia officinalis has the effects of relieving pain, removing water toxin, promoting blood circulation, removing blood stasis and the like, and the main components are magnolol and honokiol, and has the effects of anti-inflammatory, antibacterial and antioxidant; the Saviae Miltiorrhizae radix extract mainly contains liposoluble non-quinone pigment compounds such as tanshinone IIA, tanshinone IIB, cryptotanshinone and their isomers, and has antibacterial effect; the cortex moutan extract contains paeonoside, paeonol, paeoniflorin, hydroxy paeoniflorin, benzoylpaeoniflorin and volatile oil, and has effects of clearing heat, cooling blood, promoting blood circulation, and removing blood stasis. The three components are combined in a reasonable proportion, so that various skin repair functions can be considered, and the effect is obvious.
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Fig. 1 is a schematic diagram of a skin tone test chart.
Detailed Description
In order that the invention may be understood more fully, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended claims. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. These embodiments are provided so that this disclosure will be thorough and complete. It should be understood that the experimental methods in the following examples, in which specific conditions are not noted, are generally performed under conventional conditions or under conditions suggested by the manufacturer. The various reagents commonly used in the examples are all commercially available products.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
A skin care composition of the present invention comprises the following components: magnolia bark extract, red sage extract and tree peony bark extract; the mass ratio of the magnolia bark extract, the red sage root extract and the tree peony bark extract is (0.2-0.4) to 4 (0.2-0.4).
Preferably, the mass ratio of the magnolia bark extract, the red sage root extract and the tree peony bark extract is (0.25-0.35) to 4 (0.25-0.35).
More preferably, the mass ratio of the magnolia bark extract, the red sage root extract and the tree peony bark extract is 0.3:4:0.3.
A skin care cosmetic of the present invention comprising a skin care composition as described in any one of the preceding claims and cosmetically acceptable adjuvants.
In some of these embodiments, the cosmetic comprises: lotions, emulsions, creams, gels.
Preferably, the raw materials of the cosmetic comprise the following components: tocopheryl acetate, cetostearyl alcohol, pentaerythritol distearate, phytosterol esters, glycerol tris (ethylhexanoate), polydimethylsiloxane, hydrogenated polydecene, magnolia bark extract, cetostearyl alcohol and cetostearyl glucoside, glycerol stearate and PEG-100 stearate, pure water, carbomers, allantoin, sodium hyaluronate, glycerol, propylene glycol, sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80, salvia extract, tree peony bark extract, ethanol, phenoxyethanol, ethylhexyl glycerol, aminomethylpropanol.
More preferably, the cosmetic comprises the following raw materials in parts by weight:
Figure BDA0002182748380000041
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Figure BDA0002182748380000051
further preferably, the raw materials comprise the following components in parts by weight:
Figure BDA0002182748380000052
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Figure BDA0002182748380000061
the preparation method of the skin care cosmetic provided by the invention comprises the following steps of:
1) Mixing tocopheryl acetate, cetostearyl alcohol, pentaerythritol distearate, phytosterol esters, glycerol tri (ethylhexanoate), polydimethylsiloxane, hydrogenated polydecene, cortex magnoliae officinalis bark extract, cetostearyl alcohol and cetostearyl glucoside, glycerol stearate and PEG-100 stearate, and dissolving under heating for later use;
2) Mixing pure water, carbomer, allantoin, sodium hyaluronate, glycerol and propylene glycol, homogenizing, dispersing, and heating for dissolving;
3) Adding the product of the step 2) and the product of the step 1) into an emulsifying pot for mixing, vacuumizing, homogenizing and dispersing;
4) Adding sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80 phase and Saviae Miltiorrhizae radix extract into the product of step 3), and cooling;
5) Heating and dissolving cortex moutan extract and ethanol together, and mixing with the product of step 4);
6) Adding phenoxyethanol, ethylhexyl glycerol and essence, stirring uniformly, and mixing with the product of the step 5); then adding the aminomethyl propanol solution, and homogenizing and uniformly mixing.
Preferably, the method comprises the following steps:
1) Mixing tocopheryl acetate, cetostearyl alcohol, pentaerythritol distearate, phytosterol esters, glycerol tris (ethylhexanoate), polydimethylsiloxane, hydrogenated polydecene, cortex magnoliae officinalis bark extract, cetostearyl alcohol and cetostearyl glucoside, glycerol stearate and PEG-100 stearate, heating to 70-80 ℃ until the components are completely dissolved, and filtering for later use;
2) Mixing pure water, carbomer, allantoin, sodium hyaluronate, glycerol, and propylene glycol, homogenizing, dispersing, and heating at 75-85deg.C to dissolve completely;
3) Adding the product of the step 2) and the product of the step 1) into an emulsifying pot for mixing, pumping true to 0.05-0.1mpa, regulating the homogenization speed to 50Hz, and homogenizing for 3-5 minutes;
4) Adding sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate-80 phase and Saviae Miltiorrhizae radix extract into the product of step 3), heating to 70-80deg.C, maintaining the temperature for 20-25 min, and cooling;
5) Heating cortex moutan extract and ethanol together to 50-55deg.C until dissolution is complete, and mixing with the product of step 4) when the temperature of emulsifying pot is reduced to 45-50deg.C;
6) Cooling the emulsifying pot to 41-43 ℃, adding phenoxyethanol, ethylhexyl glycerol and essence, uniformly stirring, and mixing with the product of the step 5); then adding the aminomethyl propanol solution, homogenizing at 50Hz for 10-15 seconds, and mixing uniformly.
The sources of the components of the plant extract according to the embodiment of the invention are as follows:
the Magnolia bark extract is obtained by extracting Magnolia bark with ethanol or purchasing;
in some of these embodiments, the specific preparation method is as follows (process parameters may also be optionally adjusted): extracting cortex Magnolia officinalis bark with 3-10 times of 30-90% ethanol under reflux for 0.5-3 hr, filtering to obtain ethanol extractive solution, and concentrating.
The Saviae Miltiorrhizae radix extract is prepared by extracting Saviae Miltiorrhizae radix with ethanol and water; in some of these embodiments, the specific preparation method is as follows (process parameters may also be optionally adjusted):
(1) Adding 3-10 times of 30-90% ethanol into Saviae Miltiorrhizae radix, reflux extracting for 0.5-3 hr, filtering to obtain ethanol extractive solution, and collecting residue A;
(2) Adding water 3-10 times of the medicinal materials into the medicinal residue A, decocting for 0.5-3 hours, filtering to obtain water extract, and discarding the medicinal residue B;
(3) Stirring the alcohol extract in the step (1), cooling the alcohol extract, standing, absorbing the supernatant to obtain an alcohol extract supernatant, stirring the water extract in the step (2), cooling the water extract, standing, and absorbing the supernatant to obtain a water extract supernatant;
(4) Concentrating the ethanol extractive supernatant and the water extractive supernatant respectively, mixing, and filtering while hot to obtain Saviae Miltiorrhizae radix extract.
In the embodiment of the invention, the preparation method specifically comprises the following steps:
(1) Adding 5 times of 75% ethanol into Saviae Miltiorrhizae radix, reflux extracting for 2 hr, filtering to obtain ethanol extractive solution, and collecting residue A;
(2) Adding 5 times of water into the medicinal residue A, decocting for 2 hours, filtering to obtain water extract, and discarding the medicinal residue B;
(3) Stirring the alcohol extract in the step (1) for 30 minutes, reducing the temperature of the alcohol extract to below 15 ℃, standing for 12 hours, absorbing the supernatant to obtain an alcohol extract supernatant, stirring the water extract in the step (2) for 30 minutes, reducing the temperature of the water extract to below 15 ℃, standing for 12 hours, and absorbing the supernatant to obtain a water extract supernatant;
(4) Concentrating the ethanol extractive supernatant and the water extractive supernatant respectively, mixing, and filtering while hot to obtain Saviae Miltiorrhizae radix extract.
Cortex moutan extract: extracting cortex moutan with ethanol and water;
in some of these embodiments, the specific preparation method is as follows (process parameters may also be optionally adjusted):
(1) Extracting cortex moutan with 3-10 times of 30-90% ethanol under reflux for 0.5-3 hr, filtering to obtain ethanol extractive solution, and collecting residue C;
(2) Adding water 3-10 times of the medicinal materials into the residue C, decocting for 0.5-3 hours, filtering to obtain water extract, and discarding the residue D;
(3) Stirring the alcohol extract in the step (1), cooling the alcohol extract, standing, absorbing the supernatant to obtain an alcohol extract supernatant, stirring the water extract in the step (2), cooling the water extract, standing, and absorbing the supernatant to obtain a water extract supernatant;
(4) Concentrating the supernatant, mixing, and filtering to obtain cortex moutan extract.
In the embodiment of the invention, the preparation method specifically comprises the following steps:
(1) Extracting cortex moutan with 5 times of 50% ethanol under reflux for 1 hr, filtering to obtain ethanol extractive solution, and collecting residue C;
(2) Adding 5 times of water into the residue C, decocting for 2 hr, filtering to obtain water extractive solution, and discarding residue D;
(3) Stirring the alcohol extract in the step (1) for 30 minutes, reducing the temperature of the alcohol extract to below 15 ℃, standing for 12 hours, absorbing the supernatant to obtain an alcohol extract supernatant, stirring the water extract in the step (2) for 30 minutes, reducing the temperature of the water extract to below 15 ℃, standing for 12 hours, and absorbing the supernatant to obtain a water extract supernatant;
(4) Concentrating the supernatant, mixing, and filtering to obtain cortex moutan extract.
The present invention will be described in detail with reference to specific examples.
Examples 1-2, comparative examples 1-5
The skin care cosmetic provided by the embodiment of the invention comprises the following raw materials in parts by weight as shown in table 1.
Table 1 list of the raw materials in parts by weight for examples and comparative examples
Figure BDA0002182748380000091
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Figure BDA0002182748380000101
The preparation process of the cosmetic comprises the following steps:
1. cleaning and sterilizing the emulsifying pot, the oil tank and the water tank of the equipment in advance.
2. Adding phase A into oil tank, stirring, and heating to 70-80deg.C for dissolving completely. Filtering for standby.
3. Adding phase B into a water tank, homogenizing and dispersing, and heating to 75-85deg.C under stirring to dissolve completely. Filtering for standby.
4. Adding the phase B obtained by filtering in the step 3 into an emulsifying pot, adding the phase A into the emulsifying pot, pumping to be true, adjusting the homogenizing speed to 50HZ at-0.05-0.1 mpa, and homogenizing for 3-5 minutes.
5. Adding the phase C and phase D into an emulsifying pot, preserving the temperature at 70-80 ℃ for 20-25 minutes, and then starting to cool.
6. Heating the E phase together at 50-55deg.C to dissolve completely, cooling to 45-50deg.C, adding into emulsifying pot, and stirring.
7. Cooling to 42 deg.c, adding F phase, stirring, adding G phase, homogenizing at 50HZ speed for 10-15 s, and making into skin care cosmetic emulsion.
Effect experiment
1. Whitening effect test
1. Test population: women aged 20-40 years
2. Test sample: cosmetic emulsions prepared in examples 1-2 and examples 1-5, and commercially available cosmetic emulsions (Yulan oil whitening skin cream with whitening effect, beijing moisturizing pearl whitening and freckle-removing cream, hantaimei whitening and freckle-removing cream)
3. Test sample application method: the dosage is about 0.5 ml/time for use in the morning and evening every day.
4. Evaluation criteria: the skin color test card detects and compares the whitening effect. As shown in fig. 1, the skin color test color chart is divided into 16 color number grades from light color to dark color, the skin color deep-light span before and after use (20 days) is 3 color numbers and more than 3 color number grades, and the skin color test color chart is judged to have obvious whitening effect; the span is 1-2 color numbers, and the whitening effect is judged to be general; and judging that the skin color is not changed if no obvious color number is changed.
And simultaneously, the effects of melanin, skin half-dots and skin transparency and brightness are observed by naked eyes.
The results are shown in Table 1, and the data in the tables correspond to the percentage of the total number of people using the cosmetics.
Figure BDA0002182748380000111
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Figure BDA0002182748380000121
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Figure BDA0002182748380000131
2. Acne removal effect test
10 women with acne skin at 18-30 years old test volunteers, 5 emulsions prepared by using the emulsion prepared in the embodiment 1 of the invention, and 5 extracts of Yizhen grass plant coagulation extraction acne-removing cream with commercial acne-removing effect, wherein the extracts are specifically as follows:
inventive example 1 emulsion group:
(1) Forest women: 20 years old, college students
0.5ml of the composition is used in the morning and evening every day, and the vaccinia inflammation is obviously disappeared after 1-2 days of use, and has no pain and itching, and the vaccinia wound is gradually recovered after 2-3 days.
(2) Ten thousand women: 27 years old, company staff
The medicine is used for 0.5ml each day in the morning and evening, after 1-2 days, most of the vaccinia inflammation is obviously disappeared, a small part of the vaccinia inflammation is reduced, no pain and itching are caused, and the vaccinia wound is gradually recovered at 3-4 days.
(3) Plum women: 28 years old, company staff
0.5ml of the composition is used in the morning and evening every day, and the vaccinia inflammation is obviously disappeared after 1-2 days of use, and has no pain and itching, and the vaccinia wound is gradually recovered after 2-3 days.
(4) Lu lady: 28 years old, company staff
Before sleeping at night, 0.5ml of the composition is used for 2-3 days, the vaccinia inflammation is obviously disappeared, no pain and itching are caused, and the vaccinia wound is gradually recovered at 2-3 days.
(5) Plum women: 23 years old, college students
Before sleeping at night, 0.5ml of the composition is used for 2-3 days, the vaccinia inflammation is obviously disappeared, no pain and itching are caused, and the vaccinia wound is gradually recovered at 2-3 days.
Commercial acne-removing effect of the Yizhen grass plant gel extraction acne-removing cream group:
(6) Plum women: 29 years old, company staff
0.5ml of the composition is used in the morning and evening every day, and after 2-3 days of use, the vaccinia inflammation is relieved, the pain and itching are relieved after 1 day of use, and the symptoms are relieved after 2-3 days of use, so that the vaccinia wound is gradually recovered.
(7) Female: 22 years old, company staff
0.5ml of the composition is used in the morning and evening every day, and after 2-3 days of use, the inflammation of the vaccinia is reduced, the symptoms are reduced after 1-2 days of use and 3-4 days of use, and the acne wound is gradually recovered.
(8) Bang lady: 25 years old, company staff
0.5ml of the composition is used in the morning and evening every day, and after 2-3 days of use, the vaccinia inflammation is relieved, the pain and itching are relieved after 1 day of use, and the symptoms are relieved after 2-3 days of use, so that the vaccinia wound is gradually recovered.
(9) Collapse women: 21 years old, college students
0.5ml of the composition is used in the morning and evening every day, and after 2-3 days of use, the vaccinia inflammation is relieved, the pain and itching are relieved after 1 day of use, and the symptoms are relieved after 2-3 days of use, so that the vaccinia wound is gradually recovered.
(10) Female: 18 years old, college students
0.5ml of the composition is used in the morning and evening every day, and the vaccinia inflammation is reduced after 2-3 days, the composition is slightly painful and itching-free after 1 day, and the vaccinia wound is gradually recovered after 2-3 days.
The technical features of the above embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The foregoing examples illustrate only a few embodiments of the invention and are described in detail herein without thereby limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.

Claims (10)

1. A skin care composition characterized by the components: magnolia bark extract, red sage extract and tree peony bark extract;
the mass ratio of the magnolia bark extract, the red sage root extract and the tree peony bark extract is (0.2-0.4) to 4 (0.2-0.4);
the Magnolia bark extract is extracted from Magnolia bark with ethanol, and the preparation method comprises: reflux extracting cortex Magnolia officinalis bark with 3-10 times of 30-90% ethanol for 0.5-3 hr, filtering to obtain ethanol extractive solution, and concentrating to obtain cortex Magnolia officinalis extract;
the radix salviae miltiorrhizae extract is extracted from radix salviae miltiorrhizae by ethanol and water, and the preparation method comprises the following steps:
(1) Adding 3-10 times of 30-90% ethanol into Saviae Miltiorrhizae radix, reflux extracting for 0.5-3 hr, filtering to obtain ethanol extractive solution, and collecting residue A;
(2) Adding water 3-10 times of the medicinal materials into the medicinal residue A, decocting for 0.5-3 hours, filtering to obtain water extract, and discarding the medicinal residue B;
(3) Stirring the alcohol extract in the step (1), cooling the alcohol extract, standing, absorbing the supernatant to obtain an alcohol extract supernatant, stirring the water extract in the step (2), cooling the water extract, standing, and absorbing the supernatant to obtain a water extract supernatant;
(4) Concentrating the ethanol extract supernatant and the water extract supernatant respectively, mixing, and filtering while the mixture is hot to obtain the radix salviae miltiorrhizae extract;
the cortex moutan extract is extracted from cortex moutan by ethanol and water, and the preparation method comprises the following steps:
(1) Extracting cortex moutan with 3-10 times of 30-90% ethanol under reflux for 0.5-3 hr, filtering to obtain ethanol extractive solution, and collecting residue C;
(2) Adding water 3-10 times of the medicinal materials into the residue C, decocting for 0.5-3 hours, filtering to obtain water extract, and discarding the residue D;
(3) Stirring the alcohol extract in the step (1), cooling the alcohol extract, standing, absorbing the supernatant to obtain an alcohol extract supernatant, stirring the water extract in the step (2), cooling the water extract, standing, and absorbing the supernatant to obtain a water extract supernatant;
(4) Concentrating the supernatant, mixing, and filtering to obtain cortex moutan extract.
2. The skin care composition according to claim 1, wherein the mass ratio of magnolia bark extract, red sage extract and tree peony bark extract is (0.25-0.35) to 4 to (0.25-0.35).
3. The skin care composition according to claim 2, wherein the mass ratio of magnolia bark extract, red sage extract and tree peony bark extract is 0.3:4:0.3.
4. Use of a skin care composition according to any one of claims 1-3 in the preparation of a cosmetic product.
5. A skin care cosmetic comprising the skin care composition of any one of claims 1 to 3 and cosmetically acceptable adjuvants.
6. The skin care cosmetic according to claim 5, wherein the cosmetic is a lotion, emulsion, cream or gel.
7. The skin care cosmetic according to claim 5 or 6, wherein the raw materials comprise the following components in parts by weight:
a skin care composition according to any one of claims 1 to 3 in an amount of 3 to 7 parts; 93-97 parts of auxiliary materials acceptable in cosmetics.
8. The skin care cosmetic according to claim 7, wherein the cosmetically acceptable auxiliary materials comprise the following components in parts by weight:
0.5-1.5 parts of tocopheryl acetate;
0.3-0.6 part of cetostearyl alcohol;
0.5-1.5 parts of pentaerythritol distearate;
0.5-1.5 parts of phytosterol esters;
3-5 parts of triglyceride (ethyl caproic acid);
1-3 parts of polydimethylsiloxane;
3-5 parts of hydrogenated polydecene;
cetyl stearyl alcohol and cetyl stearyl glucoside 2-3 parts
Glycerol stearate and PEG-100 stearate 1-1.5 parts;
65-70 parts of pure water;
0.1-0.3 parts of carbomer;
0.1-0.3 parts of allantoin;
0.05-0.15 part of sodium hyaluronate;
2-4 parts of glycerol;
2-4 parts of propylene glycol;
0.2-0.4 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer;
0.2-0.4 part of isohexadecane;
polysorbate-80 0.2-0.4 part;
2-4 parts of ethanol;
0.1-0.4 part of phenoxyethanol;
0.1-0.4 part of ethylhexyl glycerol;
0.05-0.1 part of aminomethyl propanol.
9. A method of preparing a skin care cosmetic product according to claim 8, comprising the steps of:
1) Mixing cortex Magnolia officinalis extract with tocopheryl acetate, cetostearyl alcohol, pentaerythritol distearate, phytosterol esters, glycerol tri (ethylhexanoate), polydimethylsiloxane, hydrogenated polydecene, cetostearyl alcohol and cetostearyl glucoside, glycerol stearate and PEG-100 stearate, and dissolving under heating;
2) Mixing pure water, carbomer, allantoin, sodium hyaluronate, glycerol and propylene glycol, homogenizing, dispersing, and heating for dissolving;
3) Emulsifying and mixing the product of the step 2) and the product of the step 1), and homogenizing and dispersing under vacuum condition;
4) Adding the red sage root extract, sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 into the product of the step 3), and cooling;
5) Heating and dissolving cortex moutan extract and ethanol together, and mixing with the product of step 4);
6) Adding phenoxyethanol, ethylhexyl glycerol and essence, stirring uniformly, and mixing with the product of the step 5); then adding the aminomethyl propanol solution, and homogenizing and uniformly mixing.
10. The method of manufacturing according to claim 9, comprising the steps of:
1) Mixing cortex Magnolia officinalis extract with tocopheryl acetate, cetostearyl alcohol, pentaerythritol distearate, phytosterol esters, glycerol tris (ethylhexanoate), polydimethylsiloxane, hydrogenated polydecene, cetostearyl alcohol and cetostearyl glucoside, glycerol stearate and PEG-100 stearate, heating to 70-80deg.C until the mixture is completely dissolved, and filtering;
2) Mixing pure water, carbomer, allantoin, sodium hyaluronate, glycerol, and propylene glycol, homogenizing, dispersing, and heating at 75-85deg.C to dissolve completely;
3) Adding the product of the step 2) and the product of the step 1) into an emulsifying pot, mixing, vacuumizing to-0.05-0.1 MPa, regulating the homogenization speed to 50Hz, and homogenizing for 3-5 minutes;
4) Adding Saviae Miltiorrhizae radix extract, sodium acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane and polysorbate-80 into the product of step 3), heating to 70-80deg.C, maintaining the temperature for 20-25 min, and cooling;
5) Heating cortex moutan extract and ethanol together to 50-55deg.C until dissolution is complete, and mixing with the product of step 4) when the temperature of emulsifying pot is reduced to 45-50deg.C;
6) Cooling the emulsifying pot to 41-43 ℃, adding phenoxyethanol, ethylhexyl glycerol and essence, uniformly stirring, and mixing with the product of the step 5); then adding the aminomethyl propanol solution, homogenizing at 50Hz for 10-15 seconds, and mixing uniformly.
CN201910802574.3A 2019-08-28 2019-08-28 Skin care composition, cosmetic and method for producing same Active CN112438915B (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000067187A (en) * 1999-04-24 2000-11-15 김상회 Cosmetics containing Paeonia Suffruticosa Andrews extracts
CN101822624A (en) * 2009-03-06 2010-09-08 童玉新 Composition containing thioctic acid and extract of root of red-rooted salvia and application thereof in cosmetics
CN103432244A (en) * 2013-09-11 2013-12-11 余红波 Composition having acne removing function
CN103876989A (en) * 2014-04-23 2014-06-25 上海相宜本草化妆品股份有限公司 Application of tree peony bark extract to preparation of skin whitening composition for external use and preparation method of tree peony bark extract
CN104688637A (en) * 2013-12-04 2015-06-10 肖峰 Red sage root acne-removing repairing cream
CN106176480A (en) * 2016-08-30 2016-12-07 广州品赫化妆品有限公司 A kind of food grade compositions with antiseptic activity and the application in cosmetics thereof
CN107898681A (en) * 2017-11-17 2018-04-13 珠海姗拉娜化妆品有限公司 A kind of Novel acne treatment naturally extracts composition, acne eliminating cream and preparation method thereof
CN110051761A (en) * 2019-06-12 2019-07-26 郑州植美堂生物科技有限公司 Topical agent of acne-removing inflammation-diminishing and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100335081C (en) * 2002-01-26 2007-09-05 Mst有限公司 Composition containing moutan root bark extract as active ingredient

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000067187A (en) * 1999-04-24 2000-11-15 김상회 Cosmetics containing Paeonia Suffruticosa Andrews extracts
CN101822624A (en) * 2009-03-06 2010-09-08 童玉新 Composition containing thioctic acid and extract of root of red-rooted salvia and application thereof in cosmetics
CN103432244A (en) * 2013-09-11 2013-12-11 余红波 Composition having acne removing function
CN104688637A (en) * 2013-12-04 2015-06-10 肖峰 Red sage root acne-removing repairing cream
CN103876989A (en) * 2014-04-23 2014-06-25 上海相宜本草化妆品股份有限公司 Application of tree peony bark extract to preparation of skin whitening composition for external use and preparation method of tree peony bark extract
CN106176480A (en) * 2016-08-30 2016-12-07 广州品赫化妆品有限公司 A kind of food grade compositions with antiseptic activity and the application in cosmetics thereof
CN107898681A (en) * 2017-11-17 2018-04-13 珠海姗拉娜化妆品有限公司 A kind of Novel acne treatment naturally extracts composition, acne eliminating cream and preparation method thereof
CN110051761A (en) * 2019-06-12 2019-07-26 郑州植美堂生物科技有限公司 Topical agent of acne-removing inflammation-diminishing and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
皮类药用植物美容护肤功效的研究进展;曾鸣等;《中国美容医学》;20160131;第25卷(第1期);第100-104页 *

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