CN111671696A

CN111671696A - Acne removing cream and preparation method thereof

Info

Publication number: CN111671696A
Application number: CN202010734040.4A
Authority: CN
Inventors: 林立宇
Original assignee: Guangzhou Pugao Management Consulting Co ltd
Current assignee: Guangzhou Pugao Management Consulting Co ltd
Priority date: 2020-07-27
Filing date: 2020-07-27
Publication date: 2020-09-18

Abstract

The invention discloses acne-removing cream and a preparation method thereof. The acne removing cream comprises the following components: emulsifier, thickener, plant extract I, plant extract II, emollient and low erucic acid rapeseed oil; wherein the plant extract I comprises arnebia euchroma (Royle) Johnst extract; the plant extract II comprises radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix astragali Mongolici extract, fructus Pyracanthae extract, radix Althaeae Roseae extract and Glycyrrhrizae radix extract. The acne-removing cream is based on acne-removing components prepared from Sinkiang lithospermum extract, salvia miltiorrhiza root extract, clove bud extract, astragalus membranaceus root extract, pyracantha fortuneana fruit extract, marshmallow root extract and licorice root extract, is mild and non-irritant, has excellent antibacterial and acne-removing effects, and can effectively care skin; moreover, the acne removing cream is convenient to carry and use. The acne removing cream with uniform dispersion and good stability can be prepared by the preparation method.

Description

Acne removing cream and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to acne removing cream and a preparation method thereof.

Background

Acne is a chronic inflammation of hair follicles and sebaceous glands, is called acne or comedo in medicine and mainly occurs in the areas of face, chest and back and other fatty areas. The generation principle is mainly that the hair growth process promotes sebaceous glands to secrete grease, so that the hair follicles and sebaceous gland ducts are hyperkeratotic, cells of hyperkeratosis and sebum are combined and deposited on the hair follicles to form fat granules, and the fat granules are decomposed by propionibacterium acnes in the hair follicles to generate free fatty acid, so that inflammation is caused to form acne. The etiology of the disease is mainly related to secretion of hormone level, cutin metabolism, hypersecretion of sebaceous glands and infection of propionibacterium acnes, and clinical manifestations of the disease are characterized by polymorphic skin lesions such as comedo, papule, pustule and nodule which are easy to appear on the face.

Due to the characteristic that acne is well developed on the face, acne marks are easily left on the face of a person, even the acne marks are serious to the situation that sunken scars or hypertrophic scars are left, and the face of the person is greatly damaged. Along with the aggravation of pollution of natural environment, pollutants in the air are increased, the risk that the facial skin of a human body is invaded by the environment is higher, the living and working pressure of people is increased, the probability of illness state caused by skin metabolic disorder due to endocrine dyscrasia of the human body is increased, and the breeding probability of acne is greatly increased.

In order to prevent acne, the skin needs to be treated in time to ensure the health of the skin. The treatment method mainly aims at removing acnes and can radically eliminate the acnes and the influence thereof. The existing treatment method mainly comprises acne removal products, is convenient to use and low in cost, and comprises medicines, cosmeceuticals and cosmetics. The acne-removing cosmetic can remove acne, care skin and remove acne marks and acne marks. However, although numerous anti-acne cosmetics are available on the market, a large amount of chemical compounds are added, so that the skin of a human body is easily stimulated and is further injured; in addition, many existing acne-removing cosmetics seek skin care in the form of a plurality of sheets, deviate from the essence of acne removal, have poor acne-removing effect, and cannot meet the requirements of people on acne removal and skin care; meanwhile, the existing acne-removing cosmetics are mainly gels, water aqua or cream, and are inconvenient to carry.

Disclosure of Invention

The invention aims to provide acne removing cream aiming at the defects or shortcomings of the prior acne removing cosmetics in the prior art, such as easy skin irritation, poor acne removing effect, inconvenience in carrying and the like. The acne-removing cream is based on acne-removing components prepared from Sinkiang lithospermum extract, salvia miltiorrhiza root extract, clove bud extract, astragalus membranaceus root extract, pyracantha fortuneana fruit extract, marshmallow root extract and licorice root extract, is mild and non-irritant, has excellent antibacterial and acne-removing effects, and can effectively care skin; moreover, the acne removing cream is convenient to carry and use.

The invention also aims to provide a method for preparing the acne removing cream.

The purpose of the invention is realized by the following technical scheme.

The acne removing cream comprises the following components in percentage by mass:

1.0-7.0% of emulsifier, 8.0-34.0% of thickener, 0.001-0.03% of plant extract I, 0.12-3.36% of plant extract II, 4.0-25.0% of emollient and the balance of low erucic acid rapeseed oil;

the plant extract I comprises Sinkiang arnebia root extract; the plant extract II comprises radix Salviae Miltiorrhizae extract, flos Caryophylli bud extract, radix astragali Mongolici extract, fructus Pyracanthae extract, radix Althaeae Roseae extract and Glycyrrhrizae radix extract.

In a preferred embodiment, the plant extract II comprises the following components in a mass ratio of (6-8): (2-4): (1-3): (1-3): (1-3): (1-3) a red sage root extract, a clove bud extract, an astragalus membranaceus root extract, a pyracantha fortuneana fruit extract, an althea officinalis root extract and a licorice root extract.

In a more preferred embodiment, the plant extract ii comprises a mixture of two or more of the following components in a mass ratio of 6: 3: 1: 1: 1:1, an extract of salvia miltiorrhiza, an extract of lilac buds, an extract of astragalus membranaceus roots, an extract of pyracantha fortuneana, an extract of marshmallow roots and an extract of licorice roots.

In a preferred embodiment, the addition amount of the arnebia euchroma (Royle) Johnst extract is 0.01% by mass of the acne removing cream.

In a preferred embodiment, the emulsifier comprises cetyl alcohol.

In a preferred embodiment, the thickening agent comprises, by mass, 2.0-7.0% of synthetic wax, 4.0-15.0% of beeswax and 2.0-12.0% of sucrose acetate isobutyrate.

In a preferred embodiment, the emollient comprises, by mass, 2.0-10.0% of squalane and 2.0-15.0% of glycerol tri (behenic acid/isostearic acid/eicosanedioic acid).

In a preferred embodiment, the acne cream further comprises the following components in percentage by mass: 5.0-12.0% of rape sterols, 0.1-0.8% of menthol, 0.235-5.32% of caprylic/capric triglyceride, 0.0025-0.35% of lecithin and 0.2-2.0% of tocopherol.

The method for preparing the acne removing cream comprises the following steps:

s1, weighing the raw material components according to the mass percentage, mixing the emulsifier, the thickener, the emollient and the rape sterol, heating to 80 ℃ under stirring at 30r/min, preserving heat for 10 minutes, completely melting, and beginning to cool;

s2, cooling to 60-62 ℃, adding the plant extract I, the plant extract II, the menthol, the caprylic/capric triglyceride, the lecithin and the tocopherol, continuously stirring, keeping the temperature for 10 minutes, completely and uniformly dispersing, and continuously cooling;

s3, cooling to 55 ℃, and discharging to obtain the acne removing cream.

In a preferred embodiment, in step S2, the plant extract ii and the lecithin are premixed with the caprylic/capric triglyceride and then added to the mixture.

Compared with the prior art, the invention has the following advantages and beneficial effects:

according to the acne-removing cream, the Xinjiang alkanna tinctoria extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the acne-removing components of the licorice root extract are added, and the Xinjiang alkanna tinctoria extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract are mutually cooperated to achieve excellent antibacterial and anti-inflammatory effects, so that skin acne can be thoroughly removed and prevented, the acne-removing cream is good in acne-removing effect, can permeate and promote skin regeneration, skin care and repair, and new vitality and vitality are given to the skin; in addition, the arnebia euchroma extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract are herbal extracts, and are natural in source, so that the acne removing paste system does not need to be added with a preservative due to good antibacterial and antibacterial effects, is mild and non-irritant, and is higher in safety.

In addition, the acne-removing cream is an ointment system, is moist but not greasy, is in a rod shape, is convenient to carry and use, is directly smeared on a place with acne and can be locally used.

According to the preparation method disclosed by the invention, the acne removing cream with uniform dispersion and good stability is prepared by strictly controlling the reaction process and the adding sequence of the raw materials according to the characteristics of the raw material components in the acne removing cream.

Detailed Description

The technical solution of the present invention is further described in detail with reference to the following specific examples, but the scope and implementation of the present invention are not limited thereto. The present invention may be embodied in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

Also, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

The arnebia euchroma (Royle) Johnst extract is rich in alkannin, and the alkannin has excellent antibacterial effect, so that the alkannin can effectively inhibit bacteria and resist inflammation and has the effect of naturally resisting inflammation. In addition, alkannin also has good free radical scavenging ability, and can rapidly infiltrate into skin, promote skin regeneration, promote wound healing, and lighten skin spots.

The Salvia miltiorrhiza root extract is derived from the root of Salvia miltiorrhiza, wherein the main component comprises phenolic acids and diterpenes. The salvia miltiorrhiza root extract has better anti-inflammatory effect and also shows good pharmacological effect on the antibacterial effect. In addition, the salvia miltiorrhiza root extract also has the function of relieving endothelial injury, can promote endothelial repair and wound healing, and can lighten the macula.

The flos Caryophylli bud extract is mainly derived from dried bud of flos Caryophylli of Myrtaceae, and contains eugenol as main ingredient. The clove extract has strong inhibition effect on various moulds, can effectively inhibit the growth and the propagation of the moulds, has long-term effective inhibition effect, and can inhibit and wither mould spores, thereby realizing thorough antibiosis and antiphlogosis.

The Astragalus membranaceus extract contains many chemical components, including saponin, flavone, polysaccharide, amino acid, etc. The astragalus polysaccharide has obvious antagonistic effect on various moulds, has an obvious antibacterial effect, and can effectively resist viruses of other components such as flavone, amino acid and the like, so that the astragalus polysaccharide has an excellent antibacterial function. In addition, the contained components such as saponin, flavone and the like also have excellent antioxidant effect, can improve cell activity and promote skin regeneration, and has good repairing effect on skin.

The pyracantha extract is a multi-purpose flower and fruit plant which can be eaten as medicine and can be viewed, and the fruit, root and leaf of the plant can be used as medicine. The pyracantha fortuneana fruit extract is rich in rutin, hyperin and other flavonoid compounds, has excellent antioxidant and whitening effects, and simultaneously shows the effects of diminishing inflammation and eliminating swelling and toxin.

The radix Althaeae Roseae extract is rich in flavonoids, and has good protection effect on ultraviolet ray. In addition, it has effects of activating cathepsin, proliferating fibroblast, eliminating superoxide radical, promoting skin metabolism, and resisting aging. Meanwhile, the compound has an inhibitory effect on activation of a kappa B receptor and reflects anti-inflammatory capability.

Research on proliferation of muscle cells, promotion of proliferation of vascular endothelial cells, promotion of collagen-4 type production, inhibition of NO production, and the like shows that licorice root extract has a promoting effect on improvement of skin activity and the like. In addition, the licorice root extract has obvious inhibition effect on various bacteria and good anti-inflammatory effect.

In the prior art, acne-removing paste prepared by matching Sinkiang lithospermum extract, salvia miltiorrhiza root extract, clove bud extract, astragalus membranaceus root extract, pyracantha fortuneana fruit extract, marshmallow root extract and licorice root extract is not seen. According to the acne removing cream, the acne removing components of the Sinkiang lithospermum extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract are matched, and the components are synergistic with one another, so that the acne removing cream has excellent antibacterial and anti-inflammatory effects, can thoroughly remove and prevent skin acne, can permeate and promote skin regeneration, nurses and repairs the skin, promotes wound healing caused by acne, and gives new vitality and vitality to the skin; in addition, the arnebia euchroma extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract are herbal extracts, and are natural in source, so that the acne removing paste system does not need to be added with a preservative due to good antibacterial and antibacterial effects, is mild and non-irritant, and is higher in safety.

In a preferred embodiment, the acne removing cream provided by the invention comprises the following plant extract II in a mass ratio of (6-8): (2-4): (1-3): (1-3): (1-3): (1-3) a red sage root extract, a clove bud extract, an astragalus membranaceus root extract, a pyracantha fortuneana fruit extract, an althea officinalis root extract and a licorice root extract.

In a more preferred embodiment, the plant extract ii of the acne cream of the present invention comprises 6: 3: 1: 1: 1:1, an extract of salvia miltiorrhiza, an extract of lilac buds, an extract of astragalus membranaceus roots, an extract of pyracantha fortuneana, an extract of marshmallow roots and an extract of licorice roots.

In a preferred embodiment, the acne removing cream provided by the invention comprises 0.01% of Sinkiang arnebia root extract in percentage by mass.

In a preferred embodiment, the emulsifier comprises cetyl alcohol.

The anti-acne cream is an ointment system, and is emulsified by an emulsifying system of cetyl alcohol and a thickening system of synthetic wax, beeswax and sucrose acetate isobutyrate, so that the whole cream is in a rod shape, is moist but not greasy, is convenient to carry and use, is directly smeared on a acne-growing place during use, and can be locally used.

In a preferred embodiment, the acne cream of the present invention further comprises, by mass percentage of the acne cream:

5.0-12.0% of rape sterols, 0.1-0.8% of menthol, 0.235-5.32% of caprylic/capric triglyceride, 0.0025-0.35% of lecithin and 0.2-2.0% of tocopherol.

The technical solution of the present invention will be described in detail with reference to the following embodiments.

Examples 1 to 5

The raw material composition of the acne removal cream of examples 1-5 is shown in table 1 by mass percentage.

Table 1 raw material composition (mass percentage, total 100%) of acne removing cream of examples 1 to 5

In examples 1 to 5, the composition of the plant extract I is shown in Table 2.

Table 2 composition (mass ratio) of plant extract ii in the acne cream of examples 1 to 5

The acne removal cream of the embodiments 1-5 is prepared by the following method, and comprises the following specific steps:

and the plant extract II and the lecithin are premixed by adopting the caprylic/capric triglyceride and then added into the mixed material.

S3, cooling to 55 ℃, and discharging to obtain the acne removing cream.

Comparative example 1

Compared with example 1, the acne-removing cream of the comparative example does not contain Sinkiang arnebia root extract.

Comparative example 2

Compared with example 1, the acne-removing cream of the comparative example does not contain a salvia miltiorrhiza root extract and a clove bud extract, and the plant extract II comprises an astragalus membranaceus root extract, a pyracantha fortuneana fruit extract, an marshmallow root extract and a licorice root extract in a mass ratio of 3:2:1: 1.

Comparative example 3

Compared with example 1, the acne-removing cream of the comparative example does not contain the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract and the marshmallow root extract, and the plant extract II comprises the salvia miltiorrhiza root extract, the clove bud extract and the licorice root extract in a mass ratio of 7:2: 1.

Comparative example 4

Compared with example 1, the acne-removing cream of the comparative example does not contain salvia miltiorrhiza root extract, clove bud extract, astragalus membranaceus root extract, pyracantha fortuneana fruit extract, marshmallow root extract and licorice root extract.

Comparative example 5

Compared with example 1, the acne-removing cream of the comparative example does not contain Sinkiang arnebia root extract, salvia miltiorrhiza root extract, clove bud extract and licorice root extract, and the plant extract II comprises the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract and the marshmallow root extract in a mass ratio of 3:2: 1.

According to the preparation method of the acne-removing cream in the embodiment 1, the acne-removing cream in the comparative example 1-5 is prepared.

1. Physical and chemical property test

The anti-acne creams of examples 1 to 5 and comparative examples 1 to 5 were subjected to cold and heat resistance stability tests, and the test results are shown in table 3.

Table 3 appearance state and corresponding performance test results of the acne removal cream of examples 1 to 5 and comparative examples 1 to 5

The test results in table 3 show that the acne removal creams of examples 1 to 5 and comparative examples 1 to 5 have excellent physicochemical stability, which indicates that the acne removal cream of the present invention has good physicochemical stability, no abnormal defect in the cold and heat resistance test process, and good weather resistance and quality guarantee effects. The acne removing cream has good physicochemical stability in a rod-shaped form of an ointment system, so that the acne removing cream is convenient to store and store, the use convenience is further improved, the acne removing cream is convenient to carry, and the acne removing cream can meet the demand of people for use at any time when being used as an acne removing cosmetic.

2. Bacteriostasis test

Antibacterial tests were carried out on the acne removal creams of examples 1-5 and comparative examples 1-5.

In the experiment, staphylococcus aureus (ATCC 6538), trichophyton schoenleinii, candida albicans (ATCC 10231) and propionibacterium acnes (ATCC6919) are selected as experimental strains, and bacterial suspensions are prepared for bacteriostasis experiments, wherein the specific experimental operation refers to a bacteriostasis effect test method (suspension quantitative method) of 7.3 bacteriostasis type daily chemical products in QB/T2738-.

The experiment was repeated 3 times, the average was taken, the results were kept one decimal place, and the bacteriostatic test effects are shown in table 4, respectively.

Table 4 bacteriostatic ratio of anti-acne creams of examples 1 to 5 and comparative examples 1 to 5

As can be seen from the bacteriostatic test results in table 4, compared with the anti-acne creams in comparative examples 1 to 5, the anti-acne creams in examples 1 to 5 have good inhibitory effects on staphylococcus aureus, trichophyton schoenleinii, candida albicans, propionibacterium acnes and other bacteria, and have obvious bacteriostatic effects. The acne removing paste is prepared from the acne removing components of the Sinkiang lithospermum extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract, and the components are synergistic with one another, so that the acne removing paste has an excellent antibacterial effect and can effectively perform bacteriostasis and inflammation resistance.

3. Animal experiment for acne removing efficacy

Animal experiment for acne removing efficacy of the acne removing creams of examples 1-5 and comparative examples 1-5

Test samples: the acne removal cream of examples 1-5 is the acne removal cream of comparative examples 1-5.

Control sample: physiological saline.

The test method comprises the following steps: selecting 33 New Zealand white rabbits (4.5-5.0 kg of body weight, 11 females and 12 males), randomly dividing the rabbits into 11 groups (1 female and 2 males in each group), experimental groups of examples 1-5 and comparative examples 1-5 and a control group; pox is induced on the back of the ear of each group of white rabbits, and the black rabbits are continuously smeared with coal tar every day for 1 week and 1 time every day.

After the pox is caused, each group of white rabbits is respectively treated with acne removal by using a corresponding test sample and a corresponding control sample, and the samples are smeared for 2 times every day and are smeared for 3 days continuously. 24h after the last dose, after visual observation, the sections were stained with h.e. (hematoxylin-eosin), and the tissue changes were observed under an electron microscope.

And (4) analyzing the acne removing condition according to the observation result of naked eyes and the observation of the slicing result. According to the observation of the slicing result, the white rabbits treated by the acne removing cream of the examples 1-5 have complete ear skin tissue structures, normal epidermis layers and hair follicles, obvious acne removal and elimination of pockmarks through visual observation, and the slicing observation result is consistent with the visual observation result; according to observation of slicing results, the white rabbits treated by the acne removing cream in the comparative examples 1-5 have complete auricular skin tissue structure, but hair follicles on the epidermis slightly expand and slightly keratinocyte hyperplasia occur, and the acne condition is relieved through visual observation, but the acne is not obvious, so that acne marks cannot be effectively eliminated; according to the observation of the slicing result, the white rabbits after being smeared with the normal saline for removing acnes have thickened epidermis acanthosis of the ear skin tissue structure, moderate expansion of hair follicles and severe proliferation of keratinocytes, and the acne sore condition is not obviously relieved and has no acne removing effect through visual observation.

According to the test results, compared with the acne removal cream of the comparative examples 1 to 5, the acne removal cream of the examples 1 to 5 can effectively and completely remove acne, has a good acne removal effect, can carry out deep care and repair on skin, and endows the skin with new vitality and vitality.

4. Safety test

The test population: 300 people, 18-28 years old, 200 women and 100 men, and has healthy skin and no allergic history of skin diseases. The groups were randomized into 10 groups of 30 people each, 10 men and 20 women.

According to the test method of the patch for human skin of the technical Specification for cosmetic safety, the patch tests are carried out on the acne removal cream of the examples 1-5 and the acne removal cream of the comparative examples 1-5, and the results are recorded according to the grading standard of skin reaction, and the test results are shown in the table 5.

Wherein, the skin reaction grading standard is as follows: negative reaction, grade 0. Suspicious response, only faint erythema, grade 1. Weak positive reaction (erythema reaction), erythema, infiltration, edema, and possibly papules, grade 2. A strong positive reaction (herpes response) with erythema, infiltration, edema, papules, herpes, which may be beyond the test area, grade 3. The positive reaction (the confluent herpes reaction) is extremely strong, obvious erythema, serious infiltration, edema and confluent herpes occur, and the reaction exceeds the tested area, grade 4.

Table 5 spot test results of the anti-acne creams of examples 1 to 5 and comparative examples 1 to 5

As can be seen from the patch test results in table 5, the anti-acne creams of examples 1 to 5 and comparative examples 1 to 5 are non-irritating to human body in the patch test. In the acne removing cream disclosed by the invention, the compatible arnebia euchroma extract, salvia miltiorrhiza root extract, clove bud extract, astragalus membranaceus root extract, pyracantha fortunei fruit extract, marshmallow root extract and licorice root extract are herbal extracts, are natural sources, have good antibacterial and antibacterial effects, are mild and non-irritant while no preservative is added in the acne removing cream system, are high in safety, can effectively remove acnes and care skin, and do not cause secondary damage to human skin.

5. Acne treatment efficacy test

The test population: 150 people, 20-30 years old, 68 women, 82 men and people with acne on face. The acne removal cream is divided into 10 groups at random, each group contains 15 people, and each group is respectively suitable for the acne removal cream of the embodiment 1-5 and the acne removal cream of the comparative example 1-5.

The test method comprises the following steps: the test subject uses the corresponding test samples 1 time in the morning and at night every day, and after continuously using the test samples for 3 days and 7 days, the photo MAX skin mirror image analysis management system is used for quantitatively testing the number of acnes, and the reduction ratio of the number of acnes to the initial value before use is calculated.

The test results were averaged within the group and the statistics of the test results are shown in table 6.

Table 6 acne removal test results of the acne removal creams of examples 1 to 5 and comparative examples 1 to 5

The test results in table 6 show that compared with the acne removal creams in comparative examples 1 to 5, the acne removal creams in examples 1 to 5 can effectively remove acne and have remarkable acne removal effect. The acne removing paste is prepared from the acne removing components of the Sinkiang lithospermum extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract, and the components are synergistic with one another, so that the acne removing paste has excellent antibacterial and anti-inflammatory effects, and can effectively remove skin acne.

In addition, the questionnaire of the using effect was made for the above test population, and the comprehensive statistics of the using experience evaluation (note: acne removal, acne scar repair, acne scar elimination, etc., the decrease of the number of acne was only one of the test items) was performed according to the corresponding efficacy evaluation criteria, and the statistical results are shown in table 7.

Wherein, the evaluation standard of the curative effect is as follows: (1) the basic cure is as follows: the subjective symptoms and skin damage disappear by more than 90 percent, and no new eruption appears; (2) the effect is shown: skin damage is reduced by 60-90%, and new eruptions occur occasionally; (3) the method has the following advantages: skin damage is reduced by 20-59%, and new eruptions appear; (4) and (4) invalidation: after 7 days of treatment, skin damage decreased by less than 20%, or increased instead.

TABLE 7 therapeutic effects of the acne removing creams of examples 1 to 5 and comparative examples 1 to 5

The statistical results in table 7 show that, compared with the acne removal creams in comparative examples 1 to 5, the acne removal creams in examples 1 to 5 have significant acne removal healing effect in tested population, and are high in effectiveness in removing acne and repairing skin. The acne removing cream disclosed by the invention is combined with acne removing components of the Sinkiang lithospermum extract, the salvia miltiorrhiza root extract, the clove bud extract, the astragalus membranaceus root extract, the pyracantha fortuneana fruit extract, the hollyhock root extract and the licorice root extract, and all the components are synergistic with each other, so that the acne removing cream has excellent antibacterial and anti-inflammatory effects, can thoroughly remove and prevent skin acne, can remove acne and has a good acne removing effect, effectively nurses and repairs the skin, and endows the skin with new vitality and vitality.

Various technical features of the above embodiments may be combined arbitrarily, and for the sake of brevity, all possible combinations of the technical features of the above embodiments are not described in this specification. However, as long as there is no contradiction between combinations of these technical features, the scope of the present specification should be considered as being described. Furthermore, the above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. The acne removing cream is characterized by comprising the following components in percentage by mass:

2. The acne removal cream according to claim 1, wherein the plant extract II comprises the following components in percentage by mass (6-8): (2-4): (1-3): (1-3): (1-3): (1-3) a red sage root extract, a clove bud extract, an astragalus membranaceus root extract, a pyracantha fortuneana fruit extract, an althea officinalis root extract and a licorice root extract.

3. The acne removal cream according to claim 1, wherein the plant extract II comprises, by mass, 6: 3: 1: 1: 1:1, an extract of salvia miltiorrhiza, an extract of lilac buds, an extract of astragalus membranaceus roots, an extract of pyracantha fortuneana, an extract of marshmallow roots and an extract of licorice roots.

4. The acne removal cream according to claim 1, wherein the Sinkiang arnebia root extract is added in an amount of 0.01% by mass of the acne removal cream.

5. The acne cream according to claim 1, wherein the emulsifier comprises cetyl alcohol.

6. The acne removal cream according to claim 1, wherein the thickener comprises 2.0-7.0% of synthetic wax, 4.0-15.0% of beeswax and 2.0-12.0% of sucrose acetate isobutyrate by mass percentage.

7. The acne removal cream according to claim 1, wherein the emollient comprises, by mass, 2.0-10.0% of squalane and 2.0-15.0% of glycerol tri (behenic acid/isostearic acid/eicosanedioic acid).

8. The acne removal cream according to any one of claims 1 to 7, further comprising, by mass: 5.0-12.0% of rape sterols, 0.1-0.8% of menthol, 0.235-5.32% of caprylic/capric triglyceride, 0.0025-0.35% of lecithin and 0.2-2.0% of tocopherol.

9. The method for preparing the acne treatment cream according to claim 8, which is characterized by comprising the following steps:

s3, cooling to 55 ℃, and discharging to obtain the acne removing cream.

10. The method according to claim 9, wherein in S2, the plant extract ii and the lecithin are premixed with the caprylic/capric triglyceride and then added to the mixture.