CN111297749A

CN111297749A - Hand cream containing hemp extract and preparation method thereof

Info

Publication number: CN111297749A
Application number: CN201911323162.8A
Authority: CN
Inventors: 王钲霖; 刘胜贵; 付彬彬; 李智高; 孔令羽
Original assignee: Yunnan Luxin Biopharmaceutical Co ltd
Current assignee: Yunnan Luxin Biopharmaceutical Co ltd
Priority date: 2019-12-20
Filing date: 2019-12-20
Publication date: 2020-06-19

Abstract

The invention discloses hand cream containing a hemp extract and a preparation method thereof, and belongs to the technical field of skin care products. The raw materials comprise, by weight, 5-12% of white oil, 2-6% of stearic acid, 1-5% of cetearyl alcohol, 0.5-4% of alkyl glycoside, 0.5-2.5% of vaseline, 0.1-5% of hemp extract, 1-4% of simethicone (100 cs), 0.5-3% of shea butter, 0.1-1.5% of glyceryl monostearate, 39.1-83.85% of deionized water, 3-8% of glycerol, 2-6% of butanediol, 9400.1-0.8% of carbomer, 0.05-1% of sodium hyaluronate, 0.1-0.5% of EDTA-2Na, 0.1-1% of triethanolamine, 0.05-0.3% of essence and 0.05-0.3% of preservative. The hemp extract serving as an effective active additive of the body lotion has good antibacterial and anti-inflammatory effects and wound repair effects, and can effectively recover hand problems caused by frostbite and chapping under the condition of meeting the basic moisturizing and moistening functions. Is a natural, safe and non-irritant hand cream.

Description

Hand cream containing hemp extract and preparation method thereof

Technical Field

The invention belongs to the technical field of skin care products, and particularly relates to hand cream containing a hemp extract and a preparation method thereof.

Background

Cannabis sativa L, also known as Cannabis sativa L, is a plant of the genus Cannabis of the family Moraceae, an annual upright herb, 1-3 meters high. Cannabis is generally classified into two types, industrial cannabis and narcotic cannabis, according to the proportion of Tetrahydrocannabinol (THC) contained therein. The industrial cannabis belongs to low-toxicity cannabis, wherein the content of Tetrahydrocannabinol (THC) is not more than 0.3 percent at most, and the industrial cannabis has no drug utilization value; the content of Tetrahydrocannabinol (THC) in the leaves and the flower branches of the drug marijuana is high, and the drug marijuana belongs to high-toxicity marijuana. At present, more than 80 Cannabinoids (CBs) have been isolated from cannabis, mainly including Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinol (CBN), cannabigerol (CBC), etc., wherein the content of Cannabidiol (CBD) and Tetrahydrocannabinol (THC) is the highest, and is a typical representative of cannabinoids. Researches show that Tetrahydrocannabinol (THC) has addiction hallucinogenic property, so that the application and the development of the THC in the field of medicine are greatly limited. Cannabidiol (CBD), unlike Tetrahydrocannabinol (THC), is not only a potent antioxidant, but is also a non-addictive active ingredient with no neurotoxicity, and antagonizes the psychotropic activity induced by the THC agonistic cannabinoid type I receptor (CB 1R).

In recent years, research shows that Cannabidiol (CBD) has a series of physiological functions of sedation and hypnosis, epilepsy treatment, neuroprotection, tumor treatment and the like, and is a natural active component with great application prospect in the fields of medicine and the like. In addition, industrial hemp flower and leaf extract has been used as an active ingredient or an additive in the preparation of skin care products, and there has been a trend. The skin care product has the effects of relieving pain, resisting inflammation, removing speckle, removing yellow, acne, resisting aging, resisting wrinkle and the like, and can quickly cover the skin care product consumer market, particularly the European skin care product market. The existing skin care products for whitening and moistening skin, such as removing acne, removing wrinkles and the like, basically stay temporary or repair on the surface layer, and cannot fundamentally solve the skin problem. However, Cannabidiol (CBD) and other cannabis extracts are nontoxic substances extracted from cannabis leaves and can be used in various fields such as medicines, cosmetics and health foods with high added value.

With the development of society, people pay more and more attention to the nursing of hands, and the hands are the second faces of people. However, since the hands are exposed for a long time, the frequency of use is very high, and the skin of the hands is rough and loose due to seasonal variation, polluted environment and chemical substance contact. In this age of looking at the color value, the "color value" of the hand is naturally also very high in the people's mind. Especially for women, a pair of beautiful hands often improves the pleasure of others to your, so that it becomes important to maintain the hands; there are many ways of maintaining the hands, and generally, the hand cream is a simple and effective way of applying it on a routine basis. After washing hands each time, the hands are thoroughly wiped and then hand cream is applied, so that a certain maintenance effect can be achieved. The hand cream has the main functions of supplementing oil components required by hand skin in time, moistening the skin, keeping the skin moisture, relieving dryness symptoms and preventing chapped skin in autumn and winter. However, the hand cream on the market mainly preserves moisture and nourishes, and assists in preventing freezing and cracking, and no prominent hand cream product is available for treating freezing injury and skin cracking.

Disclosure of Invention

In view of the above problems, the present invention is directed to a hand cream containing cannabis extract and a method for preparing the same. The additive hemp extract of the hand cream has multiple effects, so that the hand cream disclosed by the invention not only has the effects of moisturizing, nourishing, preventing freezing and cracking, but also has excellent effects on sterilizing, relieving itching, relieving pain and repairing wounds. Can effectively treat the hand problems caused by frostbite and skin cracking. Is a natural, safe and non-irritant hand cream.

In order to achieve the above purpose, the invention is realized by the following scheme:

a hand cream containing a hemp extract comprises the following raw materials in parts by weight:

phase A: 5-12% of white oil, 2-6% of stearic acid, 1-5% of cetostearyl alcohol, 0.5-4% of alkyl glycoside, 0.5-2.5% of vaseline, 0.1-5% of hemp extract, 1-4% of simethicone (100 cs), 0.5-3% of shea butter and 0.1-1.5% of glyceryl monostearate; phase B: 39.1-83.85% of deionized water, 3-8% of glycerol, 2-6% of butanediol, 9400.1-0.8% of carbomer, 0.05-1% of sodium hyaluronate and 0.1-0.5% of EDTA-2 Na; and C phase: 0.1-1% of triethanolamine, 0.05-0.3% of essence and 0.05-0.3% of preservative.

Preferably, the raw materials comprise the following components in parts by weight: 9% of white oil, 3.5% of stearic acid, 2.5% of cetostearyl alcohol, 2% of alkyl glycoside, 2% of vaseline, 0.1-5% of hemp extract, 1.5% of simethicone (100 cs), 1% of shea butter and 0.5% of glyceryl monostearate; phase B: 63.84-68.74% of deionized water, 5% of glycerol, 3% of butanediol, 9400.3% of carbomer, 0.06% of sodium hyaluronate and 0.1% of EDTA-2 Na; and C phase: 0.3 percent of triethanolamine, 0.2 percent of essence and 0.2 percent of preservative.

A hand cream containing cannabis extract and a preparation method thereof comprise the following steps:

(1) adding the B-phase carbomer 940 and the sodium hyaluronate into the mixed solution of the glycerol and the butanediol according to the proportion, and stirring to uniformly disperse the mixture; then adding deionized water and EDTA-2Na, heating and stirring in a water bath at 90 ℃ for 15min to form a uniform water phase.

(2) Mixing the raw materials of phase A in proportion, and heating and melting in a water bath at 80 ℃ to form a uniform oil phase.

(3) And (3) quickly adding the oil phase obtained in the step (2) into the water phase obtained in the step (1) while the oil phase is hot, and stirring for 15 min.

(4) Adding triethanolamine into the system, stirring for 5min, cooling to 50 deg.C, sequentially adding appropriate amount of essence and antiseptic, stirring for 5min, and cooling to room temperature.

The hemp extract is a general term for substances extracted from flowers, leaves, seeds and roots of industrial hemp. Comprises cannabidiol, industrial hemp full-spectrum oil, industrial hemp multispectral oil, extract concentrate and isolate.

The shea butter is solid grease extracted from the nuts of shea butter, has indexes close to those of sebum secretion grease of a human body, contains rich non-saponification components, is easy to be absorbed by the human body, can prevent drying and cracking, and further recovers and maintains the natural elasticity of skin. Also has anti-inflammatory effect.

The antiseptic is one or more of ethylparaben, sodium benzoate, benzalkonium chloride, DMDMH (dimethylol dimethyl hydantoin), and diazolidinyl urea.

The fragrances include fragrances approved for use in cosmetic codes.

Compared with the prior art, the invention has the beneficial effects that:

(1) the hemp extract serving as the effective active additive has good antibacterial and anti-inflammatory effects and wound repair effects, and can effectively recover hand problems caused by frostbite and chapping under the condition of meeting the basic moisturizing function.

(2) The hemp extract belongs to a natural plant extract, so that the hand cream is natural, safe and non-irritant.

(3) The invention has simple preparation process, definite curative effect and low cost, is suitable for large-scale production and is a product with popularization and application values.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments.

Example 1

phase A: 9% of white oil, 3.5% of stearic acid, 2.5% of cetostearyl alcohol, 2% of alkyl glycoside, 2% of vaseline, 0.5% of cannabidiol, 1.5% of simethicone (100 cs), 1% of shea butter and 0.5% of glyceryl monostearate.

Phase B: 68.34% of deionized water, 5% of glycerol, 3% of butanediol, 9400.3% of carbomer, 0.06% of sodium hyaluronate and 0.1% of EDTA-2 Na.

And C phase: triethanolamine 0.3%, papaya essence 0.2%, and sodium benzoate 0.2%.

(1) adding 0.3g of carbomer 940 and 0.06g of sodium hyaluronate into the mixed solution of 5g of glycerol and 3g of butanediol, and stirring to uniformly disperse the phase B; 68.34g of deionized water and 0.1g of EDTA-2Na are then added, and the mixture is heated and stirred in a water bath at 90 ℃ for 15min to form a uniform water phase.

(2) Mixing phase A with 9g white oil, 3.5g stearic acid, 2.5g cetostearyl alcohol, 2g alkyl glycoside, 2g vaseline, 1.5g dimethyl silicone oil (100 cs), 1g shea butter, 0.5g cannabidiol, and 0.5g glyceryl monostearate, and heating in water bath at 80 deg.C to melt to obtain uniform oil phase.

(4) Adding 0.3g triethanolamine into the system, stirring for 5min, cooling the system to 50 deg.C, sequentially adding 0.2g fructus Chaenomelis essence and 0.2g sodium benzoate, stirring for 5min, and cooling to room temperature.

Example 2

phase A: 9% of white oil, 3.5% of stearic acid, 2.5% of cetostearyl alcohol, 2% of alkyl glycoside, 2% of vaseline, 1% of cannabidiol, 1.5% of simethicone (100 cs), 1% of shea butter and 0.5% of glyceryl monostearate.

Phase B: 67.84% of deionized water, 5% of glycerol, 3% of butanediol, 9400.3% of carbomer, 0.06% of sodium hyaluronate and 0.1% of EDTA-2 Na.

A hand cream containing cannabis extract and method of preparation are as in example 1.

Example 3

phase A: 9% of white oil, 3.5% of stearic acid, 2.5% of cetostearyl alcohol, 2% of alkyl glycoside, 2% of vaseline, 1% of industrial hemp full spectrum oil, 1.5% of simethicone (100 cs), 1% of shea butter and 0.5% of glyceryl monostearate.

Example 4

phase A: 9% of white oil, 3.5% of stearic acid, 2.5% of cetostearyl alcohol, 2% of alkyl glycoside, 2% of vaseline, 1% of hemp extract, 1.5% of simethicone (100 cs), 1% of shea butter and 0.5% of glyceryl monostearate.

Experimental example 1 examination of stability of hand cream

Dividing the hand cream prepared in example 1 into 4 parts, and placing the first part in a cool and ventilated environment at room temperature; the second part is placed in a direct sunlight environment; the third part is placed in a thermostat at 45 ℃; the fourth part is placed in a refrigerator at the temperature of 2 ℃; after three months of storage, the color, uniformity and whether the mildew or rot phenomenon exists are respectively observed. The result shows that the prepared hand cream basically has no change, bright color and no color change under the high-temperature, normal-temperature and low-temperature environments; the uniformity is good, and no mildew occurs; in the direct sunlight environment, the hand cream has the tendency of dehydration and hardening.

Experimental results show that the hand cream prepared by the invention has good stability in a conventional environment. The storage mode is to avoid long-term storage in direct sunlight.

Experimental example 2 hand cream moisturizing effect test

1. A subject: dry skin, dry hand skinning experimenter. 300 adolescents and middle-aged men and women having the above-mentioned symptoms were selected as subjects.

2. Test samples: example 1 hand cream.

3. The using method comprises the following steps: taking a proper amount of the hand cream in the example 1, and uniformly smearing the hand cream on a hand; it is administered in the morning and evening for 15 days.

4. And (3) evaluation standard of moistening and moisturizing effect:

and (3) satisfaction: after the hand cream is applied, hands are fresh and cool and not dry, and the skin of the hands can still be kept plump within 6 hours after the hand cream is used;

the method has the following advantages: after the hand cream is applied, the hand is fresh and not dry, but the duration time is not more than 2h, and the hand is dried and skinned again;

and (4) invalidation: after smearing, the hands are still dry and skinned.

5. According to the evaluation standards, 300 tested persons are randomly divided into two groups, the experimental group uses the hand cream in the example 1, the control group does not use any skin care product, the trial effect is counted, and the statistical result is shown in the table 1.

Grouping	Satisfaction (number of people)	Effective (number of people)	Invalid (number of people)
				Experimental group	98	52	0
Control group	0	0	150

As shown in the statistical results in Table 1, the hand cream prepared by the invention can effectively moisten hand skin, and can keep moisture for a long time to enable the skin to be plump and not dry.

Experimental example 3 hand cream repair effect test

1. A subject: patients with frostbite and chapping hands. 200 adolescents and middle-aged men and women having the above-mentioned symptoms were selected as subjects.

2. Test samples: example 1 hand cream.

3. The using method comprises the following steps: the appropriate amount is uniformly applied to the affected part of the hand, once in the morning and at night, and continuously used for 15 days.

4. The repair effect evaluation standard is as follows:

and (3) healing: the symptoms completely disappeared;

the method has the following advantages: the symptoms are obviously improved or improved;

and (4) invalidation: no improvement in symptoms.

5. According to the evaluation criteria, 200 test persons were randomly divided into two groups, the experimental group used the hand cream of example 1, the control group used no skin care product, the treatment effect was counted after 1 month, and the statistical results are shown in table 2.

TABLE 2 repair Effect statistics

Grouping	Recovery (number of people)	Effective (number of people)	Invalid (number of people)
				Experimental group	62	36	2
Control group	0	5	95

As can be seen from the table 2, the hand cream prepared by the invention has very good effect on repairing frostbite and chapping, and the cure rate and the effective rate are as high as 98%; the hand cream prepared by the invention has good treatment effect on frostbite and chapping.

The above examples are merely illustrative of the present invention and do not limit the scope of the present invention in any way. It will be apparent to those skilled in the art that equivalent embodiments or modifications without departing from the technical spirit of the present invention are within the scope of the present invention.

Claims

1. A hand cream containing a hemp extract comprises the following raw materials in parts by weight:

2. A hand cream containing cannabis extract and a preparation method thereof comprise the following steps:

1) adding the B-phase carbomer 940 and the sodium hyaluronate into the mixed solution of the glycerol and the butanediol according to the proportion, and stirring to uniformly disperse the mixture; adding deionized water and EDTA-2Na, heating in water bath at 90 deg.C, stirring for 15min to form uniform water phase;

(2) mixing the raw materials of the phase A according to a proportion, heating and melting in a water bath at 80 ℃ to form a uniform oil phase;

(3) quickly adding the oil phase obtained in the step (2) into the water phase obtained in the step (1) while the oil phase is hot, and stirring for 15 min;

3. The hand cream containing cannabis extract and the preparation method thereof as claimed in claim 1 and claim 2, wherein the cannabis extract is a generic term of substances extracted from leaves, seeds and roots of industrial cannabis, including cannabidiol, industrial cannabis full spectrum oil, industrial cannabis multispectral oil, extract concentrate and isolate.

4. The hand cream containing cannabis sativa extract and the preparation method thereof as claimed in claim 1 and claim 2, wherein the preservative is one or more of ethylparaben, sodium benzoate, benzalkonium chloride, DMDMH (dimethyloldimethylhydantoin), diazolidinyl urea.

5. A hand cream containing cannabis extract and method of preparation thereof as claimed in claims 1 and 2, wherein the perfume comprises perfumes approved for use in cosmetic codes.