CN112426454A - 一种具有抗焦虑作用的中药复方组合物及其制备方法与应用 - Google Patents
一种具有抗焦虑作用的中药复方组合物及其制备方法与应用 Download PDFInfo
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Abstract
Description
组别 | 剂量 | 动物数 |
对照组 | / | 12 |
地西泮组 | 2mg/kg | 12 |
实施例5组大剂量 | 446.67mg/kg | 12 |
实施例6组大剂量 | 446.67mg/kg | 12 |
实施例6组小剂量 | 223.33mg/kg | 12 |
组别 | 动物数 | OE% | OT% |
对照组 | 9 | 0.2348±0.01689 | 0.1260±0.02201 |
地西泮组 | 9 | 0.3061±0.02734* | 0.1981±0.03287* |
实施例5组大剂量 | 8 | 0.3383±0.02640** | 0.1919±0.01960* |
实施例6组大剂量 | 8 | 0.2915±0.01682* | 0.1965±0.02260* |
实施例6组小剂量 | 11 | 0.3386±0.02554** | 0.1899±0.02591* |
组别 | 动物数 | 明区路程 | 明区停留时间 | 明区进入次数 |
对照组 | 10 | 13399±665.3 | 131.7±5.421 | 12.10±1.027 |
地西泮组 | 12 | 18141±1011*** | 152.1±6.860* | 18.92±1.540** |
实施例5组大剂量 | 8 | 16861±907.1** | 147.5±3.737* | 20.00±1.535*** |
实施例6组大剂量 | 11 | 15432±695.8* | 139.8±7.128 | 15.64±1.146* |
实施例6组小剂量 | 9 | 15664±928.9* | 150.8±7.514* | 17.11±1.670** |
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CN202011437190.5A CN112426454B (zh) | 2020-12-07 | 2020-12-07 | 一种具有抗焦虑作用的中药复方组合物及其制备方法与应用 |
PCT/CN2020/136657 WO2022120906A1 (zh) | 2020-12-07 | 2020-12-16 | 一种具有抗焦虑作用的中药复方组合物及其制备方法与应用 |
US17/315,224 US20220175865A1 (en) | 2020-12-07 | 2021-05-07 | Traditional chinese medicine compound composition with anti-anxiety effect and preparation method and applications thereof |
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Citations (5)
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CN101310740A (zh) * | 2007-05-24 | 2008-11-26 | 上海欣生源药业有限公司 | 一种抗焦虑复方中药及其制备方法 |
WO2009117953A1 (zh) * | 2008-03-25 | 2009-10-01 | 深圳力瑞医药科技有限公司 | 一种具有抗抑郁、抗焦虑作用的药物组合物及其制备方法 |
CN103861005A (zh) * | 2014-03-26 | 2014-06-18 | 胡向仟 | 一种具有抗焦虑作用的中药组合物 |
CN104042720A (zh) * | 2014-07-08 | 2014-09-17 | 河南中医学院 | 具有防治糖尿病并发抑郁症的中药及其应用 |
CN110538232A (zh) * | 2019-09-30 | 2019-12-06 | 青岛琛蓝医药科技发展有限公司 | 一种抗抑郁的复合制剂及其制备方法 |
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CN100515440C (zh) * | 2003-12-26 | 2009-07-22 | 广州中医药大学 | 一种从丹栀逍遥散中提取的组合物及其应用 |
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Patent Citations (5)
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