CN112426368A - Toothpaste with tooth stain removing effect and preparation method thereof - Google Patents

Toothpaste with tooth stain removing effect and preparation method thereof Download PDF

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Publication number
CN112426368A
CN112426368A CN202011423720.0A CN202011423720A CN112426368A CN 112426368 A CN112426368 A CN 112426368A CN 202011423720 A CN202011423720 A CN 202011423720A CN 112426368 A CN112426368 A CN 112426368A
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percent
toothpaste
sodium
mixture
water
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施裔磊
费凡
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Shanghai Maxam Co ltd
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Shanghai Maxam Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88—Polyamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides toothpaste with the function of removing tooth stains and a preparation method thereof, and the toothpaste comprises the following components in percentage by weight: 10-75% of sorbitol, 0.5-5% of polyethylene glycol-32, 2-30% of hydrated silica, 0.6-2.6% of thickening agent, 0.15-0.35% of saccharin sodium, 0-5.0% of tetrasodium pyrophosphate, 0-1.42% of anti-caries component, 0-10% of sodium phytate, 0-10% of sodium polyaspartate, 0-5% of pentasodium tripolyphosphate, 0-0.1% of tranexamic acid, 0-0.05% of pearl powder, 1.5-4.5% of foaming agent, 0.5-2.0% of essence, 0-0.6% of pigment, 0.2-2% of appearance modifier and the balance of water. The invention provides the toothpaste which has the effects of whitening and protecting teeth and removing tooth stains by adding the stain removing components such as tetrasodium pyrophosphate, sodium polyaspartate, pentasodium tripolyphosphate and the like into the formula of the toothpaste, can effectively prevent the deposition of the tooth stains, tartar and tartar on the surfaces of the teeth, and can prevent the deposition of the components such as magnesium, calcium and the like on the teeth, and can form an environment for inhibiting the formation of the tooth stains and dental plaques in the oral cavity after the toothpaste is used.

Description

Toothpaste with tooth stain removing effect and preparation method thereof
Technical Field
The invention relates to the field of tooth stain removing toothpaste, in particular to toothpaste with a tooth stain removing effect and a preparation method thereof.
Background
In daily work and life, people who have smoking, tea drinking and coffee drinking habits and hobbies are large in groups for refreshing or simple hobbies, and yellow and black tooth stains, particularly smoke stains, tea stains or coffee stains, can be generated on the surfaces of teeth after long-term smoking, coffee drinking or tea drinking, so that the oral hygiene and attractiveness are greatly influenced. The smoke stain, tea stain or coffee stain is generated because a substance called caffeine reacts with acidic secretion in the oral cavity for a long time and adheres to the teeth, and when too much tooth stain adheres to the teeth, it becomes tooth diffraction matter such as tartar and dental plaque which is hard to remove.
In the current technology, effective prevention of removing tooth stain and tartar is tooth washing, but tooth washing damages enamel on the surface of teeth, makes teeth more fragile, and the process of tooth washing is painful, so tooth washing is not a long-term measure for cleaning tooth stain.
With the rapid development of modern toothpaste technology, toothpaste is not only a daily necessity for whitening teeth, but functional toothpastes such as toothpaste for treating oral diseases, anti-inflammatory toothpaste and antiallergic toothpaste are available in the market at present, and are used for targeted protection and treatment of oral health of different people, however, no mature functional toothpaste specially aiming at removing tooth stains on teeth exists at present.
Disclosure of Invention
The invention provides toothpaste with a tooth stain removing effect and a preparation method thereof, and aims to solve the problems that tooth stains are difficult to remove and no functional toothpaste specially used for removing the tooth stains exists in the prior art.
In one aspect, the invention provides a toothpaste with tooth stain removing effect, which comprises the following components in percentage by weight: 10-75% of sorbitol, 0.5-5% of polyethylene glycol-32, 2-30% of hydrated silica, 0.6-2.6% of thickening agent, 0.15-0.35% of saccharin sodium, 0-5.0% of tetrasodium pyrophosphate, 0-1.42% of anti-caries component, 0-10% of sodium phytate, 0-10% of sodium polyaspartate, 0-5% of pentasodium tripolyphosphate, 0-0.1% of tranexamic acid, 0-0.05% of pearl powder, 1.5-4.5% of foaming agent, 0.5-2.0% of essence, 0-0.6% of pigment, 0.2-2% of appearance modifier and the balance of water.
Further, the thickening agent is one or more selected from cellulose gum and Chondrus crispus.
Further, the pigment is selected from one or more of CI73360, CI19140 and CI 77891.
Further, the foaming agent is selected from one or more of sodium lauryl sulfate and cocamidopropyl betaine.
Further, the anticaries component is selected from one or more of sodium monofluorophosphate and sodium fluoride.
Further, the appearance modifier is selected from one or more of love particles and white rabbit particles.
Further, the love particles comprise the following components in percentage by weight: 0.5 to 10 percent of glycerin, 2 to 15 percent of butanediol, 0.1 to 1 percent of agar, 0.2 to 2 percent of gellan gum, 0.1 to 2 percent of sodium lactate, 0.05 to 0.5 percent of carob gum, 0.001 to 0.01 percent of aluminum hydroxide, 0.01 to 0.5 percent of CI73360, 0.1 to 1.0 percent of sodium benzoate and the balance of water;
the white rabbit particles comprise the following components in percentage by mass: 0.5 to 10 percent of glycerin, 2 to 15 percent of butanediol, 0.1 to 1 percent of agar, 0.2 to 2 percent of gellan gum, 0.1 to 2 percent of sodium lactate, 0.05 to 0.5 percent of carob gum, 0.001 to 0.01 percent of aluminum hydroxide, 0.01 to 1 percent of CI77891, 0.1 to 1.0 percent of sodium benzoate and the balance of water.
In another aspect, the present invention also provides a method for preparing the toothpaste, comprising the following steps:
s1: adding polyethylene glycol-32, tetrasodium pyrophosphate, saccharin sodium, anticaries component, sodium phytate, and tranexamic acid into water, mixing, and heating to obtain mixture D1;
s2: adding pigment and pearl powder into sorbitol to form mixture D2;
s3: dispersing a thickener, pentasodium tripolyphosphate, in hydrated silica to form a mixture D3;
s4: adding mixture D1, mixture D2 and mixture D3 to an emulsifying pan to form mixture D4;
s5: adding foaming agent, essence and appearance modifier into emulsifying pot, making into paste, and packaging.
Further, the heating time is 3-9 min, and the heating temperature is 35-55 ℃.
By adopting the technical scheme, compared with the prior art, the invention has the following technical effects:
according to the toothpaste with the function of removing dental stains and the preparation method thereof, the stain removing components such as tetrasodium pyrophosphate, sodium polyaspartate, pentasodium tripolyphosphate and the like are added into the formula of the toothpaste, so that the formation of dental stains, tartar and tartar on the surfaces of teeth can be effectively prevented, the deposition of components such as magnesium, calcium and the like on the teeth can be prevented, and the environment for inhibiting the formation of dental stains and dental plaques in the oral cavity can be formed after the whole toothpaste component is used; the toothpaste also adds an anticarious component into the formula, so that the toothpaste has the effect of maintaining the health of teeth; and the love particles and the white rabbit particles are also added, so that the appearance and the feeling of the toothpaste are more favored by consumers.
Detailed Description
The invention provides toothpaste with a tooth stain removing effect, which comprises the following components in percentage by weight: 10-75% of sorbitol, 0.5-5% of polyethylene glycol-32, 2-30% of hydrated silica, 0.6-2.6% of thickening agent, 0.15-0.35% of saccharin sodium, 0-5.0% of tetrasodium pyrophosphate, 0-1.42% of anti-caries component, 0-10% of sodium phytate, 0-10% of sodium polyaspartate, 0-5% of pentasodium tripolyphosphate, 0-0.1% of tranexamic acid, 0-0.05% of pearl powder, 1.5-4.5% of foaming agent, 0.5-2.0% of essence, 0-0.6% of pigment, 0.2-2% of appearance modifier and the balance of water.
In a preferred embodiment of the invention, the thickening agent is selected from one or more of cellulose gum and Chondrus crispus.
In a preferred embodiment of the present invention, the pigment is one or more selected from CI73360, CI19140 and CI 77891.
In a preferred embodiment of the invention, the foaming agent is selected from one or more of sodium lauryl sulfate and cocamidopropyl betaine.
In a preferred embodiment of the invention, the anticaries agent is selected from one or more of sodium monofluorophosphate and sodium fluoride.
In a preferred embodiment of the invention, the appearance-improving agent is selected from one or more of love heart particles and rabbit particles.
In a preferred embodiment of the invention, the love particles comprise the following components in percentage by weight: 0.5 to 10 percent of glycerin, 2 to 15 percent of butanediol, 0.1 to 1 percent of agar, 0.2 to 2 percent of gellan gum, 0.1 to 2 percent of sodium lactate, 0.05 to 0.5 percent of carob gum, 0.001 to 0.01 percent of aluminum hydroxide, 0.01 to 0.5 percent of CI73360, 0.1 to 1.0 percent of sodium benzoate and the balance of water;
the white rabbit particles comprise the following components in percentage by mass: 0.5 to 10 percent of glycerin, 2 to 15 percent of butanediol, 0.1 to 1 percent of agar, 0.2 to 2 percent of gellan gum, 0.1 to 2 percent of sodium lactate, 0.05 to 0.5 percent of carob gum, 0.001 to 0.01 percent of aluminum hydroxide, 0.01 to 1 percent of CI77891, 0.1 to 1.0 percent of sodium benzoate and the balance of water. .
The invention also provides a preparation method of the toothpaste, which comprises the following steps:
s1: adding polyethylene glycol-32, tetrasodium pyrophosphate, saccharin sodium, anticaries component, sodium phytate, and tranexamic acid into water, mixing, and heating to obtain mixture D1;
s2: adding pigment and pearl powder into sorbitol to form mixture D2;
s3: dispersing a thickener, pentasodium tripolyphosphate, in hydrated silica to form a mixture D3;
s4: adding mixture D1, mixture D2 and mixture D3 to an emulsifying pan to form mixture D4;
s5: adding foaming agent, essence and appearance modifier into emulsifying pot, making into paste, and packaging.
In a preferred embodiment of the present invention, the heating time is 3-9 min, and the heating temperature is 35-55 ℃.
In a preferred embodiment of the present invention, the heating time is 4-7 min, and the heating temperature is 40-50 ℃.
The present invention will be described in detail and specifically with reference to the following examples to facilitate better understanding of the present invention, but the following examples do not limit the scope of the present invention.
Example 1
The embodiment provides toothpaste with the function of removing tooth stains, which comprises the following components in percentage by weight: 55% sorbitol, 2.5% polyethylene glycol-32, 10% hydrated silica, 1.5% cellulose gum, 0.1% Phragmites communis, 0.3% saccharin sodium, 4% tetrasodium pyrophosphate, 0.2% sodium monofluorophosphate, 0.25% sodium fluoride, 5% sodium phytate, 6% sodium polyaspartate, 4% pentasodium tripolyphosphate, 0.05% tranexamic acid, 0.03% pearl essence, 2% sodium lauryl sulfate, 1% cocamidopropyl betaine, 1.2% essence, 0.01% CI73360, 0.0001% CI19140, 0.1% CI77891, 0.25% love particles, 0.25% rabbit particles, and the balance water.
Wherein, the love particles comprise the following components in percentage by weight: 8% of glycerol, 10% of butanediol, 0.4% of agar, 1% of gellan gum, 1.5% of sodium lactate, 0.05% of carob gum, 0.005% of aluminum hydroxide, 0.05% of CI73360, 0.1% of sodium benzoate and the balance of water;
the white rabbit particles comprise the following components in percentage by mass: 8% of glycerol, 10% of butanediol, 0.4% of agar, 1% of gellan gum, 1.5% of sodium lactate, 0.05% of carob gum, 0.005% of aluminum hydroxide, 0.1% of CI77891, 0.1% of sodium benzoate and the balance of water.
The preparation method of the toothpaste comprises the following steps:
s1: adding polyethylene glycol-32, tetrasodium pyrophosphate, sodium saccharin, sodium monofluorophosphate, sodium fluoride, sodium phytate and tranexamic acid into water, mixing, heating for 5min at 40 deg.C to obtain mixture D1;
s2: adding CI73360, CI19140, CI77891 and pearl powder into sorbitol to mix to form mixture D2;
s3: dispersing cellulose gum, Chondrus crispus and pentasodium tripolyphosphate in hydrated silica to form a mixture D3;
s4: adding mixture D1, mixture D2 and mixture D3 to an emulsifying pan to form mixture D4;
s5: adding sodium lauryl sulfate, cocamidopropyl betaine, essence, love particles and rabbit particles into emulsifying pot, making into ointment, and packaging.
Example 2
The embodiment provides toothpaste with the function of removing tooth stains, which comprises the following components in percentage by weight: 45% of sorbitol, 2% of polyethylene glycol-32, 15% of hydrated silica, 1% of cellulose gum, 0.8% of carrageen crispa, 0.25% of saccharin sodium, 2.5% of tetrasodium pyrophosphate, 1% of sodium monofluorophosphate, 0.04% of sodium fluoride, 4% of sodium phytate, 6% of sodium polyaspartate, 1% of pentasodium tripolyphosphate, 0.05% of tranexamic acid, 0.05% of pearl essence, 1.8% of sodium lauryl sulfate, 2% of cocamidopropyl betaine, 1.5% of essence, 0.008% of CI73360, 0.4% of CI77891, 1% of love particles, 1% of white rabbit particles and the balance of water.
Wherein, the love particles comprise the following components in percentage by weight: 5% glycerol, 15% butanediol, 0.5% agar, 0.5% gellan gum, 1.5% sodium lactate, 0.1% carob gum, 0.005% aluminum hydroxide, 0.1% CI73360, 0.3% sodium benzoate, and the balance water;
the rabbit particles comprise, by mass, 5% of glycerol, 15% of butanediol, 0.5% of agar, 0.5% of gellan gum, 1.5% of sodium lactate, 0.1% of carob gum, 0.005% of aluminum hydroxide, 0.2% of CI77891, 0.3% of sodium benzoate, and the balance of water. .
The preparation method of the toothpaste comprises the following steps:
s1: adding polyethylene glycol-32, tetrasodium pyrophosphate, sodium saccharin, sodium monofluorophosphate, sodium fluoride, sodium phytate and tranexamic acid into water, mixing, heating for 6min at 45 deg.C to obtain mixture D1;
s2: adding CI73360, CI19140, CI77891 and pearl powder into sorbitol to mix to form mixture D2;
s3: dispersing cellulose gum, Chondrus crispus and pentasodium tripolyphosphate in hydrated silica to form a mixture D3;
s4: adding mixture D1, mixture D2 and mixture D3 to an emulsifying pan to form mixture D4;
s5: adding sodium lauryl sulfate, cocamidopropyl betaine, essence, love particles and rabbit particles into emulsifying pot, making into ointment, and packaging.
Example 3
The embodiment provides toothpaste with the function of removing tooth stains, which comprises the following components in percentage by weight: 65% sorbitol, 5% polyethylene glycol-32, 5% hydrated silica, 0.5% cellulose gum, 0.2% Chondrus crispus, 0.18% saccharin sodium, 1.5% tetrasodium pyrophosphate, 0.4% sodium monofluorophosphate, 0.15% sodium fluoride, 3% sodium phytate, 3% sodium polyaspartate, 1% pentasodium tripolyphosphate, 0.04% tranexamic acid, 0.04% pearl essence, 1.5% sodium lauryl sulfate, 0.5% cocamidopropyl betaine, 0.8% essence, 0.004% CI73360, 0.001% CI19140, 0.4% CI77891, 0.2% love particles, 0.2% white rabbit particles, and the balance water.
Wherein, the love particles comprise the following components in percentage by weight: 4% glycerol, 6% butanediol, 0.2% agar, 0.4% gellan gum, 0.5% sodium lactate, 0.1% carob gum, 0.003% aluminum hydroxide, 0.2% CI73360, 0.5% sodium benzoate, and the balance water;
the white rabbit particles comprise the following components in percentage by mass: 4% of glycerol, 6% of butanediol, 0.2% of agar, 0.4% of gellan gum, 0.5% of sodium lactate, 0.1% of carob gum, 0.003% of aluminum hydroxide, 0.3% of CI77891, 0.5% of sodium benzoate and the balance of water.
The preparation method of the toothpaste comprises the following steps:
s1: adding polyethylene glycol-32, tetrasodium pyrophosphate, sodium saccharin, sodium monofluorophosphate, sodium fluoride, sodium phytate and tranexamic acid into water, mixing, heating for 8min at 50 deg.C to obtain mixture D1;
s2: adding CI73360, CI19140, CI77891 and pearl powder into sorbitol to mix to form mixture D2;
s3: dispersing cellulose gum, Chondrus crispus and pentasodium tripolyphosphate in hydrated silica to form a mixture D3;
s4: adding mixture D1, mixture D2 and mixture D3 to an emulsifying pan to form mixture D4;
s5: adding sodium lauryl sulfate, cocamidopropyl betaine, essence, love particles and rabbit particles into emulsifying pot, making into ointment, and packaging.
Verification examples
The toothpaste components provided in the examples 1, 2 and 3 are removed of four components of tetrasodium pyrophosphate, sodium phytate, sodium polyaspartate and pentasodium tripolyphosphate, other components are respectively the same as the components in the examples 1 to 3, correspondingly, the four components are not included in the preparation method, other methods are the same as the preparation methods in the examples 1 to 3, the toothpaste prepared by the technical scheme is used as the comparative examples 1 to 3, and the toothpaste provided in the comparative examples 1 to 3 have the effect of removing the black tea color source, the cigarette color source and the coffee color source through in-vitro control experiments.
The experimental consumables are:
(1) hydroxyapatite tablets;
(2) a pigment source: 2 g/bag of Litton yellow tea bag; nestle alcohol coffee, 1.8 g/bag; huangguoshu brand cigarettes;
(3) 80-mesh and 120-mesh sand paper;
(4) a toothbrush.
The test method comprises the following steps:
(1) dividing hydroxyapatite sheets (hereinafter referred to as HA sheets) into A, B, C three groups, wherein each two HA sheets are respectively polished by 80-mesh coarse sand paper and 120-mesh fine sand paper, removing dirt on the surfaces of the HA sheets, washing the HA sheets by deionized water, and drying the HA sheets in an oven at 70 ℃ for later use;
(2) taking the HA sheets out of the oven, after naturally cooling, numbering each HA sheet by A1, A2, B1, B2, C1 and C2, and measuring the L, a and B values of the six HA sheets by a color difference meter, namely the L, a and B values of the HA sheets before dyeing; three points of a triangle in the middle of the HA sheet are taken for measurement, and an average value is taken;
(3) immersing the dried HA tablets in artificial saliva, and storing for 24h in an oven at 40 ℃;
(4) taking out six HA tablets from the artificial saliva, preparing a color source, and respectively dissolving 2g of black tea in 100mL of water to prepare a black tea color source; dissolving 2.7g of black coffee in 100mL of water to prepare a coffee color source; lighting the cigarette to prepare a cigarette color source;
a, B washing two groups of HA tablets with deionized water, and respectively placing the washed HA tablets into a black tea color source and a coffee color source for dyeing; cleaning group C HA sheets with deionized water, drying, repeatedly fumigating with cigarette until HA sheets surface turns from white to brown;
(5) after dyeing, washing the three groups of HA tablets by deionized water, and naturally drying;
(6) respectively measuring the values of L, a and b of the three groups of HA dirty sheets by using a color difference meter, carrying out triangulation three times, and taking an average value to obtain the values of L, a and b after the HA sheets are dyed; (it must be ensured that the baseline data for each group of samples is not different, P value is greater than 0.05)
(7) Mixing the toothpaste provided by the examples 1-3 and the toothpaste provided by the comparative examples 1-3 with deionized water according to the proportion of 1:10 respectively, and stirring uniformly;
(8) fixing three dyed groups of HA sheets and a toothbrush on a toothpaste friction value testing machine, wherein HA sheets A1, B1 and C1 respectively adopt the toothpaste slurry provided by examples 1-3, HA sheets A2, B2 and C2 respectively adopt the toothpaste slurry provided by comparative examples 1-3, the toothpaste slurry is poured into stainless steel bottom cups, 50mL of toothpaste slurry is poured into each cup, 8000 times of reciprocating friction is carried out at the frequency of 100 times/minute, and the toothpaste slurry is stirred every 20 minutes to ensure that the abrasive material is kept uniform and does not precipitate;
(9) after the rubbing experiment of the toothpaste is finished, taking down three groups of HA tablets, washing with deionized water, and naturally drying for later use;
(10) measuring the L, a and b values of three groups of HA tablets after the friction experiment of the toothpaste, performing triangulation three times, and removing the average value to obtain the L, a and b values of the HA tablets after the friction experiment of the toothpaste;
the experimental color difference value calculation formula is as follows:
Figure BDA0002823728770000081
Δ L ═ L value after rubbing-L value after dyeing
Δ a ═ a value after rub-a value after stain
Δ b-b value after rubbing-b value after dyeing
The larger the Delta E value is, the more remarkable the stain removing effect is;
data were processed with the SPSS19.0 software package and differences between groups were compared using ANOVA analysis of variance and SNK with a significance level of 0.05.
The experimental data are as follows:
group A: HA tablet No. a 1:
table 1 a1 HA leaf black tea color source pre-dyeing data
Figure BDA0002823728770000082
Figure BDA0002823728770000091
Table 2 a1 HA leaf black tea color source post-dyeing data
Numbering L* a* b*
1 +65.45 +3.01 +19.11
2 +65.34 +3.19 +19.81
3 +65.75 +3.54 +20.01
4 +65.13 +3.07 +18.83
5 +64.69 +4.05 +20.20
6 +64.94 +3.63 +20.01
7 +65.50 +3.28 +19.17
Mean value of +65.26 +3.40 +19.60
TABLE 3A 1 HA tablets data after rubbing the toothpaste of example 1
Numbering L* a* b*
1 +70.28 -1.10 +11.68
2 +70.66 -1.53 +11.67
3 +70.17 -0.75 +11.55
4 +69.73 -1.20 +11.37
5 +70.38 -1.42 +12.10
6 +70.56 -0.87 +11.33
7 +69.45 -0.70 +11.87
Mean value of +70.18 -1.08 +11.65
The total Δ E color difference mean of the HA tablets No. a1 was calculated to be 10.37, and the standard deviation was calculated to be 0.82.
HA tablet No. a 2:
table 4 a2 HA leaf black tea color source pre-dyeing data
Figure BDA0002823728770000092
Figure BDA0002823728770000101
Table 5 a2 HA leaf black tea color source post-dyeing data
Numbering L* a* b*
1 +64.34 +3.74 +20.22
2 +64.64 +4.37 +20.81
3 +66.04 +3.01 +19.19
4 +65.36 +3.68 +20.47
5 +64.15 +3.71 +20.38
6 +64.72 +3.90 +20.35
7 +65.38 +3.32 +20.13
Mean value of +64.95 +3.68 +20.22
TABLE 6A 2 HA tablets data after abrasion of comparative toothpaste
Numbering L* a* b*
1 +67.41 +0.85 +14.60
2 +68.31 +0.49 +13.20
3 +68.57 +0.21 +13.31
4 +70.05 -0.51 +13.05
5 +66.94 +0.43 +13.94
6 +67.94 +0.90 +14.44
7 +66.95 +1.25 +15.49
Mean value of +68.02 +0.52 +14.00
The average value of the total color difference Δ E of the HA sheet No. a2 was calculated to be 7.64, and the standard deviation was calculated to be 1.49.
Group B: HA tablet No. B1:
TABLE 7B 1 HA coffee color Source before staining data
Numbering L* a* b*
1 +76.16 -2.69 +7.23
2 +76.00 -2.62 +6.99
3 +75.99 -2.30 +7.80
4 +76.64 -2.58 +7.29
5 +76.99 -2.57 +6.44
6 +77.92 -2.39 +7.77
7 +77.54 -2.28 +7.69
Mean value of +76.75 -2.49 +7.32
TABLE 8B 1 data from HA coffee color source after staining
Numbering L* a* b*
1 +66.06 +0.84 +18.05
2 +65.83 +0.78 +17.51
3 +66.02 +1.08 +18.10
4 +65.73 +1.20 +18.15
5 +67.12 +0.68 +17.30
6 +66.33 +1.35 +18.48
7 +65.89 +1.83 +19.66
Mean value of +66.14 +1.11 +18.18
TABLE 9B 1 HA tablets data after rubbing of toothpaste of example 2
Figure BDA0002823728770000111
Figure BDA0002823728770000121
The average value of the total color difference Δ E of the HA sheet No. B1 was calculated to be 11.47, and the standard deviation was calculated to be 0.87.
HA tablet No. B2:
TABLE 10B 2 HA disks coffee source pre-staining data
Numbering L* a* b*
1 +76.46 -2.58 +7.00
2 +77.12 -2.55 +6.64
3 +77.51 -2.41 +6.76
4 +77.33 -2.45 +7.50
5 +77.04 -2.53 +7.63
6 +77.77 -2.21 +7.43
7 +76.24 -2.65 +6.76
Mean value of +77.07 -2.48 +7.10
TABLE 11B 2 data from HA coffee color source after staining
Numbering L* a* b*
1 +66.25 +0.66 +17.22
2 +65.32 +1.02 +17.16
3 +65.73 +0.82 +16.94
4 +65.77 +1.61 +19.28
5 +66.41 +0.70 +17.18
6 +65.57 +1.60 +18.14
7 +66.45 +0.55 +17.48
Mean value of +65.93 +0.99 +17.63
Table 12B 2 HA tablet comparative toothpaste post abrasion data
Figure BDA0002823728770000122
Figure BDA0002823728770000131
The average value of the total color difference Δ E of the HA sheet No. B2 was calculated to be 8.83, and the standard deviation was calculated to be 1.11.
Group C: HA tablet No. C1:
data before staining HA color sources of cigarette No. 13C 1 Table
Numbering L* a* b*
1 +76.30 -2.29 +7.38
2 +76.75 -2.69 +6.68
3 +77.57 -2.30 +7.09
4 +73.14 -2.57 +2.23
5 +76.77 -2.55 +6.81
6 +76.88 -2.41 +7.88
7 +76.04 -2.65 +6.88
Mean value of +76.21 -2.49 +6.42
Data of HA flakes cigarette color source No. 14C 1 after dyeing
Numbering L* a* b*
1 +55.9 +7.53 +33.35
2 +56.06 +7.36 +33.4
3 +56.93 +7.3 +33.97
4 +57.01 +2.83 +27.19
5 +60.17 +4.72 +29.83
6 +60.25 +5.17 +31.74
7 +60.4 +4.27 +29.8
Mean value of +58.10 +5.60 +31.33
TABLE 15 HA tablets of EXAMPLE 1C data after rubbing with toothpaste of EXAMPLE 3
Numbering L* a* b*
1 +71.31 -0.16 +16.80
2 +72.38 -1.19 +13.88
3 +73.98 -2.02 +12.76
4 +69.05 -2.68 +6.58
5 +73.39 -2.67 +11.04
6 +73.26 -2.46 +11.71
7 +72.70 -2.64 +10.25
Mean value of +72.30 -1.97 +11.86
The average value of the total color difference Δ E of the HA sheet No. C1 was calculated to be 25.33, and the standard deviation was calculated to be 1.82.
HA tablet No. C2:
TABLE 16C 2 HAS PIECE CIGARETTE COLOUR SOURCE PRE-COLORING DATA
Numbering L* a* b*
1 +76.02 -2.83 +7.07
2 +75.95 -2.66 +6.78
3 +75.99 -2.79 +7.00
4 +76.99 -2.49 +7.44
5 +76.35 -2.53 +7.00
6 +77.99 -2.36 +7.43
7 +77.98 -1.37 +7.79
Mean value of +76.75 -2.43 +7.22
Data of HA flakes of cigarette No. 17C 2 after color source staining
Figure BDA0002823728770000141
Figure BDA0002823728770000151
TABLE 18C 2 HA comparative toothpaste post abrasion data
Numbering L* a* B*
1 +71.19 -0.21 +15.72
2 +69.90 -0.63 +16.63
3 +70.79 -0.92 +18.03
4 +70.46 -0.70 +18.01
5 +70.48 -0.40 +16.77
6 +71.39 -0.03 +17.65
7 +70.99 +1.52 +19.96
Mean value of +70.74 -0.20 +17.54
The average value of the total color difference Δ E of the HA sheet No. C2 was 21.54, and the standard deviation was 2.47.
As shown by the results of the experimental data in tables 1 to 18, the performance of the toothpastes provided in examples 1 to 3 and comparative examples 1 to 3 with respect to stain removal was compared as follows:
group a (black tea color source):
example 1 (HA tablet No. a 1) Δ E ═ 7.64 > comparative example 1 (HA tablet No. a 2) Δ E ═ 10.37;
group B (coffee color source):
example 2 (HA tablet No. B1) Δ E ═ 11.47 > comparative example 2 (HA tablet No. B2) Δ E ═ 8.83;
group C (cigarette color source):
example 3 (HA tablet No. C1) Δ E ═ 25.33 > comparative example 3 (HA tablet No. C2) Δ E ═ 21.54;
the in vitro experiment results show that: the toothpaste provided by the embodiment 1-3 is effective in removing tooth stains such as black tea stains, coffee stains and smoke stains, and the effect of the toothpaste is superior to that of the toothpaste provided by the comparative example 1-3.
The embodiments of the present invention have been described in detail, but the embodiments are merely examples, and the present invention is not limited to the embodiments described above. Any equivalent modifications and substitutions to those skilled in the art are also within the scope of the present invention. Accordingly, equivalent changes and modifications made without departing from the spirit and scope of the present invention should be covered by the present invention.

Claims (9)

1. The toothpaste with the tooth stain removing effect is characterized by comprising the following components in percentage by weight: 10-75% of sorbitol, 0.5-5% of polyethylene glycol-32, 2-30% of hydrated silica, 0.6-2.6% of thickening agent, 0.15-0.35% of saccharin sodium, 0-5.0% of tetrasodium pyrophosphate, 0-1.42% of anticaries component, 0-10% of sodium phytate, 0-10% of sodium polyaspartate, 0-5% of pentasodium tripolyphosphate, 0-0.1% of tranexamic acid, 0-0.05% of pearl powder, 1.5-4.5% of foaming agent, 0.5-2.0% of essence, 0-0.6% of pigment, 0.2-2% of appearance modifier and the balance of water.
2. The toothpaste of claim 1, wherein said thickening agent is selected from one or more of cellulose gum and Chondrus crispus.
3. The toothpaste of claim 1, wherein said colorant is selected from the group consisting of CI73360, CI19140 and CI 77891.
4. The toothpaste according to claim 1, wherein the foaming agent is selected from one or more of sodium lauryl sulfate and cocamidopropyl betaine.
5. The toothpaste of claim 1, wherein said anticaries agent is selected from the group consisting of sodium monofluorophosphate and sodium fluoride.
6. The toothpaste of claim 1, wherein the appearance-improving agent is selected from one or more of love particles and rabbit particles.
7. The toothpaste of claim 6, wherein the love particles comprise the following components in weight percent: 0.5 to 10 percent of glycerin, 2 to 15 percent of butanediol, 0.1 to 1 percent of agar, 0.2 to 2 percent of gellan gum, 0.1 to 2 percent of sodium lactate, 0.05 to 0.5 percent of carob gum, 0.001 to 0.01 percent of aluminum hydroxide, 0.01 to 0.5 percent of CI73360, 0.1 to 1.0 percent of sodium benzoate and the balance of water;
the white rabbit particles comprise the following components in percentage by mass: 0.5 to 10 percent of glycerin, 2 to 15 percent of butanediol, 0.1 to 1 percent of agar, 0.2 to 2 percent of gellan gum, 0.1 to 2 percent of sodium lactate, 0.05 to 0.5 percent of carob gum, 0.001 to 0.01 percent of aluminum hydroxide, 0.01 to 1 percent of CI77891, 0.1 to 1.0 percent of sodium benzoate and the balance of water.
8. A method of preparing a toothpaste as claimed in any one of claims 1 to 7 comprising the steps of:
s1: adding the polyethylene glycol-32, tetrasodium pyrophosphate, sodium saccharin, anticaries components, sodium phytate and tranexamic acid into water, uniformly mixing, and heating to prepare a mixture D1;
s2: adding the pigment and pearl powder into the sorbitol to be mixed, and forming a mixture D2;
s3: dispersing said thickener, pentasodium tripolyphosphate, in said hydrated silica to form a mixture D3;
s4: adding the mixture D1, mixture D2 and mixture D3 to an emulsification pan to form mixture D4;
s5: and adding the foaming agent, the essence and the appearance modifier into the emulsifying pot to prepare paste, and filling.
9. The method according to claim 8, wherein the heating time is 3 to 9min, and the heating temperature is 35 to 55 ℃.
CN202011423720.0A 2020-12-08 2020-12-08 Toothpaste with tooth stain removing effect and preparation method thereof Pending CN112426368A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653045A (en) * 2018-06-08 2018-10-16 广东南方洁灵科技实业有限公司 A kind of toothpaste and its manufacturing method improving the black yellow problem of tooth
CN110772450A (en) * 2019-12-11 2020-02-11 苏州清馨健康科技有限公司 Polyaspartic acid sodium toothpaste
CN110787121A (en) * 2019-12-09 2020-02-14 上海绿瑞生物科技有限公司 Whitening toothpaste and preparation method thereof
CN113350206A (en) * 2021-06-25 2021-09-07 佛山市安齿生物科技有限公司 Whitening and mothproof toothpaste and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653045A (en) * 2018-06-08 2018-10-16 广东南方洁灵科技实业有限公司 A kind of toothpaste and its manufacturing method improving the black yellow problem of tooth
CN110787121A (en) * 2019-12-09 2020-02-14 上海绿瑞生物科技有限公司 Whitening toothpaste and preparation method thereof
CN110772450A (en) * 2019-12-11 2020-02-11 苏州清馨健康科技有限公司 Polyaspartic acid sodium toothpaste
CN113350206A (en) * 2021-06-25 2021-09-07 佛山市安齿生物科技有限公司 Whitening and mothproof toothpaste and preparation method thereof

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