CN110787121A

CN110787121A - Whitening toothpaste and preparation method thereof

Info

Publication number: CN110787121A
Application number: CN201911250231.7A
Authority: CN
Inventors: 张明磊; 姜春鹏
Original assignee: Shanghai Lurui Biotechnology Co Ltd
Current assignee: Shanghai Lurui Biotechnology Co Ltd
Priority date: 2019-12-09
Filing date: 2019-12-09
Publication date: 2020-02-14

Abstract

The invention relates to the technical field of daily chemicals, in particular to whitening toothpaste and a preparation method thereof. The whitening toothpaste at least comprises the following components in percentage by weight: 10-40% of an abrasive, 0.1-5% of polyphosphate, 1-10% of pyrophosphate, 0.1-10% of hydroxyapatite, 0.001-0.50% of pearling agent, 0.5-4% of fluoride, 0.1-1.5% of thickening agent, 1-10% of sweetening agent, 0.01-2% of preservative, 0.1-0.5% of humectant, 1.5-6% of foaming agent and water to make up 100%. The invention provides a whitening and repairing toothpaste, which has the following effects: 1. the lower friction performance can reduce the abrasion to teeth, the friction is mild, the teeth are protected, and the tooth cleaning agent is suitable for daily use; 2. the tooth whitening liquid has good tooth whitening effect, and can effectively remove exogenous stains and tooth stains of teeth; 3. the smooth finish of the tooth surface is improved, and the reformation of exogenous color spots is resisted; 4. inhibiting the development of stomatitis and repairing oral gingival tissue injury; 5. the alkalescent formula can inhibit the formation of oral microorganisms, refresh breath and keep oral health.

Description

Whitening toothpaste and preparation method thereof

Technical Field

The invention relates to the technical field of daily chemicals, in particular to whitening toothpaste and a preparation method thereof.

Background

Toothpaste is a common cleaning product in daily life, is used for cleaning teeth and protecting the oral hygiene. With the continuous development of science and technology, the living standard of people is gradually improved, the quality demand of toothpaste is also gradually improved, and the function is also developed from a single cleaning type to a multifunctional type.

More than half of the consumers are concerned about yellowing and staining of the teeth, as this is considered a poor indicator of oral hygiene or aging. In addition to the basic needs (plaque removal and caries prevention), consumer demand for oral care products, whitening of tooth surfaces, has a positive effect and continues to grow. Studies have shown that the range of discontent tooth color in individuals rises from 17.9% to 52.6%. This demand for whiter teeth has led to a trend towards increased use of tooth whitening products.

The formulation of toothpaste contains a large number of ingredients, each of which has a specific function. One of the key functional ingredients of whitening toothpaste is the abrasive system, the abrasive being an insoluble ingredient added to the toothpaste, primarily responsible for removing external stains, and also responsible for removing tooth biofilm and food debris. Many factors determine the action of the abrasive on the teeth, including hardness, shape, size, distribution and concentration of particles, and the brushing load applied. However, to ensure efficacy, toothpastes must have ingredients and physicochemical properties such that the therapeutic effect does not damage the oral tissues, maximizing cleaning and reducing wear of these tissues. Over-the-counter use of these products can damage the soft and hard tissues of the mouth, resulting in tooth wear, gingival atrophy and tooth sensitivity.

The invention provides whitening and repairing toothpaste with the functions of repairing, whitening, removing stains and the like, which is used for solving the technical problem of single function of the existing toothpaste, is safe to use and free of stimulation, can effectively remove stains on the surfaces of teeth, cleans the teeth and achieves the effects of protecting and whitening the teeth while keeping the oral cavity sanitary.

Disclosure of Invention

In order to solve the technical problems, the first aspect of the invention provides a whitening toothpaste, which at least comprises the following components in percentage by weight: 10-40% of an abrasive, 0.1-5% of polyphosphate, 1-10% of pyrophosphate, 0.1-10% of hydroxyapatite, 0.001-0.50% of pearling agent, 0.5-4% of fluoride, 0.1-1.5% of thickening agent, 1-10% of sweetening agent, 0.01-2% of preservative, 0.1-0.5% of humectant, 1.5-6% of foaming agent and water to make up 100%.

As a preferable technical scheme of the invention, the abrasive is a combination of compound silicon dioxide and pearl powder, and the weight ratio is 1: (0.05-0.5).

As a preferable technical scheme, the composite silicon dioxide is obtained by compounding silicon dioxide I with the particle size of 1-30 mu m and silicon dioxide II with the particle size of 10-40 mu m.

As a preferable technical scheme, the weight ratio of the silicon dioxide I to the silicon dioxide II is 1: (0.05-0.5).

As a preferable technical scheme of the invention, the particle size of the pearl powder is 0.1-10 μm.

As a preferred technical solution of the present invention, the weight ratio of the polyphosphate to the pyrophosphate is 1: (1-10).

The preferable technical scheme is characterized in that the weight ratio of the polyphosphate to the hydroxyapatite is 1: (1-10).

As a preferable technical scheme of the invention, the weight ratio of the hydroxyapatite to the fluoride is 1: (0.1-5).

As a preferable technical scheme of the invention, the particle size of the hydroxyapatite is 0.1-10 μm.

The second aspect of the invention provides a preparation method of the whitening toothpaste, which at least comprises the following steps:

(1) mixing sorbitol and water, and stirring;

(2) mixing glycerol and a thickening agent, stirring uniformly, adding into the step (1), and stirring uniformly;

(3) under the condition of stirring, adding polyphosphate, pyrophosphate, fluoride, preservative and sweetener into the step (2), and stirring until the polyphosphate, pyrophosphate, fluoride, preservative and sweetener are completely dissolved;

(4) adding a friction agent, hydroxyapatite, pearl powder and a pearling agent into the step (3) under the condition of stirring, and uniformly stirring;

(5) and (4) adding a foaming agent and essence into the mixture obtained in the step (4) under the condition of stirring, and uniformly stirring to obtain the product.

Has the advantages that: the invention provides whitening and repairing toothpaste, which achieves the purposes of continuously improving the color and luster of teeth and enhancing the whitening effect while reducing the abrasion of a friction agent to the teeth through the synergistic interaction of various effective components in the toothpaste, and has the following effects: 1. the tooth cleaning agent has lower friction performance, can reduce the abrasion to teeth, has mild friction, protects the teeth, and is suitable for daily use; 2. the whitening toothpaste has good effect of whitening teeth, and can effectively remove exogenous stains and tooth stains from the teeth; 3. the smooth finish of the tooth surface is improved, and the reformation of exogenous color spots is resisted; 4. inhibiting the development of stomatitis and repairing oral gingival tissue injury; 5. the alkalescent formula can inhibit the formation of oral microorganisms, refresh breath and keep oral health.

Detailed Description

The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.

The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.

The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.

When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.

The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.

Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.

In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.

Preferably, the whitening toothpaste at least comprises the following components in percentage by weight: 20% of an abrasive, 1% of polyphosphate, 5% of pyrophosphate, 3% of hydroxyapatite, 3% of a pearling agent, 2.4% of fluoride, 1% of a thickening agent, 2% of a sweetening agent, 0.1% of a preservative, 0.5% of a humectant, 2% of a foaming agent and water, wherein the balance is 100%.

Friction agent

In the invention, the abrasive is a combination of compound silicon dioxide and pearl powder, and the weight ratio is 1: (0.05-0.5).

Preferably, the weight ratio of the compound silicon dioxide to the pearl powder is 1: 0.1.

preferably, the pearl powder has a particle size of 0.1-10 μm.

Preferably, the pearl powder has an average particle size of 1 μm.

The source of the pearl powder is not particularly limited, and may be purchased from, but not limited to, Shanghai Yichuan chemical science and technology Co., Ltd.

Preferably, the composite silicon dioxide is obtained by compounding silicon dioxide I with the particle size of 1-30 mu m and silicon dioxide II with the particle size of 10-40 mu m.

More preferably, the weight ratio of silica I to silica II is 1: (0.05-0.5).

Most preferably, the weight ratio of the silica I to the silica II is 1: 0.1.

preferably, the silica I has an average particle diameter of 20 μm.

Preferably, the silica II has an average particle diameter of 30 μm.

The sources of the silica I and the silica II are not particularly limited, and commercially available silica I and silica II are suitable for the present invention.

The silica I and silica II are commercially available from, but not limited to, Seika specialty Chemicals (Shanghai) Co., Ltd.

In the invention, the inventor uses the silicon dioxide with two different particle sizes and the pearl powder in a compounding way, so that the prepared toothpaste can effectively remove stains on the surface of teeth without causing the abrasion of the teeth. The inventors consider that possible reasons are: because the silicon dioxide particles are spherical, the damage to teeth caused by friction of the silicon dioxide particles is far lower than that of a random friction agent such as calcium carbonate, and the silicon dioxide particles are compounded with pearl powder, so that the wear degree of the silicon dioxide particles to teeth is greatly reduced. And the silicon dioxide and the pearl powder with specific particle size range are compounded, so that the problem of agglomeration of the abrasive in the toothpaste is effectively solved, the contact area of the abrasive and the teeth is increased, various stains on the surfaces of the teeth can be effectively removed, and the effect of whitening the teeth is improved.

Polyphosphates and pyrophosphates

In the present invention, the polyphosphate is not particularly limited, and pentasodium tripolyphosphate and/or pentapotassium tripolyphosphate may be mentioned.

In the present invention, the pyrophosphate is not particularly limited, and may be selected from at least one of tetrasodium pyrophosphate, tetrapotassium pyrophosphate, trisodium monohydrogen pyrophosphate, tripotassium monohydrogen pyrophosphate, disodium dihydrogen pyrophosphate, dipotassium dihydrogen pyrophosphate, monosodium trihydrogen pyrophosphate, monopotassium monohydrogen pyrophosphate, calcium pyrophosphate, and calcium dihydrogen pyrophosphate.

Preferably, the pyrophosphate is tetrasodium pyrophosphate or tetrapotassium pyrophosphate.

Preferably, the weight ratio of the polyphosphate to the pyrophosphate is 1: (1-10).

More preferably, the weight ratio of pentasodium tripolyphosphate to tetrasodium pyrophosphate is 1: 5.

in the experimental process, the inventor finds that the whitening effect of the toothpaste on teeth can be further improved by compounding tetrasodium pyrophosphate and pentasodium tripolyphosphate. The inventors consider that possible reasons are: the polyphosphate can be complexed with metal ions (calcium ions, magnesium ions and the like) in saliva or tartar components to generate a water-soluble complex, so that tartar is separated from the surface of teeth, the substances on the surface of the teeth are effectively removed, and the condition of forming dental calculus is avoided or alleviated.

Hydroxyapatite

In the invention, the particle size of the hydroxyapatite is 0.1-10 μm.

Preferably, the hydroxyapatite has an average particle size of 1 μm.

The source of the hydroxyphosphate is not particularly limited, and it is commercially available from, but not limited to, Shanghai Zijin Kogyo Co.

In the invention, the weight ratio of the polyphosphate to the hydroxyapatite is 1: (1-10).

Preferably, the weight ratio of the polyphosphate to the hydroxyapatite is 1: 3.

the inventor unexpectedly finds that when the weight ratio of the polyphosphate to the apatite is 1: 3, the prepared toothpaste can effectively restore the concave-convex surface generated on the surface of the tooth by the friction of the abrasive, improve the surface smoothness of the tooth and prevent the reformation of exogenous color spots. The inventors considered that the strong affinity between hydroxyapatite and enamel could repair fine cracks and crevices generated after the rubbing of the compound abrasive such as silica on the tooth surface, and thus the effect of strengthening enamel could be obtained. Meanwhile, the polyphosphate contains more anions, can compete with pigments and proteins for binding sites and adsorb to the surface of the hydroxyapatite, effectively inhibits the attachment of the pigments and the proteins, and enables most of the proteins and coloring matters adsorbed to the surface of the hydroxyapatite to be desorbed.

Pearly lusterAgent for treating cancer

In the present invention, the pearlescent agent comprises mica; the particle size of the mica is 20-200 μm.

Preferably, the mica has an average particle diameter of 100 μm.

The pearlizing agent, without particular limitation, is commercially available from but not limited to Unipowder.

The inventor believes that the pearling agent mica has a good light reflection effect and can improve the tooth whitening effect after tooth brushing as a main component for physical whitening.

Fluoride compounds

In the invention, the fluoride is at least one selected from sodium fluoride, potassium fluoride, sodium monofluorophosphate and stannous fluoride.

Preferably, the fluoride is sodium fluoride and the CAS number is 7681-49-4.

In the invention, the weight ratio of the hydroxyapatite to the fluoride is 1: (0.1-5).

Preferably, the weight ratio of the hydroxyapatite to the fluoride is 1: 0.5.

the inventor believes that fluoride adapted to hydroxyapatite is hydrolyzed to generate monofluorophosphate ions or fluoride ions, which not only does not react with the hydroxyapatite to reduce the content of active fluorine and the hydroxyapatite, but also effectively promotes the mineralization process of the hydroxyapatite in dentin, and obviously improves the repair function of the hydroxyapatite toothpaste on the dentin.

Thickening agent

In the present invention, the thickener is not particularly limited, and there may be mentioned xanthan gum, carrageenan, sodium carboxymethylcellulose, cellulose gum, carbomer and the like.

Preferably, the thickener is a cellulose gum.

Sweetening agent

In the present invention, the sweetener is not particularly limited, and sodium saccharin, xylitol, sucralose, trehalose, sorbitol, sucralose, and the like can be mentioned.

Preferably, the sweetener is sorbitol.

Preservative

In the present invention, the preservative is not particularly limited, and sodium benzoate, methyl hydroxybenzoate, zinc citrate and the like can be mentioned.

Preferably, the preservative is sodium benzoate.

Moisture-retaining agent

In the present invention, the humectant is not particularly limited, and sodium hyaluronate, glycerin, sorbitol, polyethylene glycol-8 and the like can be mentioned.

Preferably, the humectant is a combination of glycerin and sodium hyaluronate, and the weight ratio is 1: (0.8-1.5).

Preferably, the weight ratio of the glycerol to the sodium hyaluronate is 1: 0.001.

foaming agent

In the present invention, the foaming agent is not particularly limited, and sodium lauryl sulfate, cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium lauryl sulfate, and the like can be mentioned.

Preferably, the foaming agent is a combination of sodium lauryl sulfate and cocamidopropyl betaine in a weight ratio of 1: (0.2-1).

Preferably, the weight ratio of the sodium lauryl sulfate to the cocamidopropyl betaine is 1: 0.8.

water (W)

In the present invention, the water is selected from one of purified water, deionized water, and distilled water.

The second aspect of the invention provides a preparation method of whitening toothpaste, which at least comprises the following steps:

(1) mixing sorbitol and water, and stirring;

(5) and (4) adding a foaming agent and essence into the mixture obtained in the step (4) under the condition of stirring, and uniformly stirring to obtain the product. The whitening toothpaste prepared by the invention not only can whiten teeth, inhibit the development of oral inflammation, repair the damage of oral gingival tissues and maintain the oral health, but also can resist decayed teeth, repair enamel and promote the health of dental tissues through the synergistic interaction of all the components.

The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.

In addition, the raw materials used are commercially available from national chemical reagents, unless otherwise specified.

Examples

Example 1

Embodiment 1 provides a whitening toothpaste, which comprises the following components in parts by weight: 20% of an abrasive, 1% of polyphosphate, 5% of tetrasodium pyrophosphate, 3% of hydroxyapatite, 0.3% of a pearling agent, 2.4% of fluoride, 1% of a thickening agent, 2% of a sweetening agent, 0.1% of a preservative, 0.3% of a humectant, 2% of a foaming agent and water, wherein the balance is 100%.

The friction agent is a combination of compound silicon dioxide and pearl powder, and the weight ratio is 1: 0.1; the average particle diameter of the pearl powder is 1 μm, and the pearl powder is purchased from Shanghai Yichuan chemical science and technology Co., Ltd; the composite silicon dioxide is obtained by compounding silicon dioxide I with the average particle size of 20 micrometers and silicon dioxide II with the average particle size of 30 micrometers, and the weight ratio of the silicon dioxide I to the silicon dioxide II is 1: 0.1; the silica I and the silica II are purchased from Shanghai Special chemistry (Shanghai) Co.

The polyphosphate is pentasodium tripolyphosphate; the pyrophosphate is tetrasodium pyrophosphate; the weight ratio of the pentasodium tripolyphosphate to the tetrasodium pyrophosphate is 1: 5.

the hydroxyapatite has an average particle size of 1 μm and is purchased from Shanghai Zijing industries, Ltd.

The weight ratio of the hydroxyapatite to the polyphosphate is 3: 1.

the pearling agent is mica; the mica had an average particle size of 1 μm and was purchased from Union micro powder.

The fluoride is sodium fluoride, and the CAS number is 7681-49-4.

The weight ratio of the hydroxyapatite to the fluoride is 1: 0.8.

the thickening agent is a combination of cellulose gum and xanthan gum, and the weight ratio is 1: 1.

the sweetener is saccharin sodium.

The preservative is sodium benzoate.

The humectant is a combination of glycerin and sorbitol, and the weight ratio is 1: 10.

the foaming agent is a combination of sodium lauryl sulfate and cocamidopropyl betaine, and the weight ratio is 2: 0.5.

the water is deionized water.

The preparation method of the whitening toothpaste comprises the following steps:

(1) mixing sorbitol and water, and stirring;

Example 2

Embodiment 2 provides a whitening toothpaste, which comprises the following components in parts by weight: 25% of an abrasive, 1% of polyphosphate, 5% of pyrophosphate, 3% of hydroxyapatite, 0.01% of a pearling agent, 2.4% of fluoride, 1% of a thickening agent, 2% of a sweetening agent, 1.0% of a preservative, 0.3% of a humectant, 2.5% of a foaming agent and water, wherein the balance is 100%.

The weight ratio of the hydroxyapatite to the polyphosphate is 3: 1.

the pearling agent is mica with the average particle size of 1 mu m, and is purchased from Nippon Kogyo Miyao.

The fluoride is sodium fluoride, and the CAS number is 7681-49-4.

The weight ratio of the hydroxyapatite to the fluoride is 1: 0.8.

the sweetener is saccharin sodium.

The preservative is sodium benzoate.

the water is deionized water.

(1) mixing sorbitol and water, and stirring;

Example 3

Embodiment 3 provides a whitening toothpaste, which comprises the following components in parts by weight: 20% of an abrasive, 0.5% of polyphosphate, 2.5% of pyrophosphate, 3% of hydroxyapatite, 0.3% of pearling agent, 2.4% of fluoride, 1% of thickening agent, 2% of sweetening agent, 0.1% of preservative, 0.3% of humectant, 2% of foaming agent and water, wherein the balance is 100%.

the average particle size of the hydroxyapatite is 1 mu m; purchased from Shanghai Zijin industries, Inc.

The weight ratio of the hydroxyapatite to the polyphosphate is 3: 1.

The fluoride is sodium fluoride, and the CAS number is 7681-49-4.

The weight ratio of the hydroxyapatite to the fluoride is 1: 0.8.

the sweetener is saccharin sodium.

The preservative is sodium benzoate.

the water is deionized water.

(1) mixing sorbitol and water, and stirring;

Example 4

Example 4 differs from example 1 in that the rubbing agent is pearl powder with a particle size of 1 μm, which is commercially available from Shanghai Yichuan chemical science and technology Co.

Example 5

Example 5 differs from example 1 in that the abrasive is silica i with a particle size of 20 μm.

Example 6

Example 6 differs from example 1 in that the abrasive is silica II having a particle size of 30 μm.

Example 7

Example 7 differs from example 1 in that no phosphate is present.

Example 8

Example 8 differs from example 1 in that no hydroxyapatite is present.

Example 9

Example 9 differs from example 1 in that no fluoride is present.

Example 10

Example 10 is a commercially available whitening toothpaste.

Example 11

Example 11 differs from example 1 in that the whitening toothpaste comprises the following components in percentage by weight: 10% of an abrasive, 0.1% of polyphosphate, 1% of pyrophosphate, 0.1% of hydroxyapatite, 0.001% of pearling agent, 0.5% of fluoride, 0.1% of thickening agent, 1% of sweetening agent, 0.01% of preservative, 0.1% of humectant, 1.5% of foaming agent and water to make up 100%.

Example 12

Example 12 differs from example 1 in that the whitening toothpaste comprises at least the following components in percentage by weight: 40% of an abrasive, 5% of polyphosphate, 10% of pyrophosphate, 10% of hydroxyapatite, 0.50% of a pearling agent, 4% of fluoride, 1.5% of a thickening agent, 10% of a sweetening agent, 2% of a preservative, 0.5% of a humectant, 6% of a foaming agent and water, wherein the balance is 100%.

Performance testing

1. Test of tooth whitening Performance

The test method comprises the following steps: taking a bovine enamel block, and carrying out embedding, polishing, cleaning and acid etching treatment to simulate the tooth surface which is possibly damaged to a certain extent in daily life. Putting the acid-etched enamel block into a dyeing solution for dyeing, wherein the dyeing solution is black tea, gastric mucin and FeCl with certain concentration₃And (3) mixing with water, keeping the dyeing for 5 days at the constant temperature of 37 ℃, and finally smoking for 30 minutes by using tobacco. Numbering and marking the stained enamel blocks, and measuring the color of the enamel by using a colorimeter to obtain L₁Selecting L₁Blocks of enamel with values of 35-45 were randomly assigned to example groups of 10 blocks each.

Fixing the enamel block on an L8-II cross tooth brushing machine, simulating tooth brushing for 8000 times, taking out the enamel sample from the tooth brushing machine, washing with water, and air drying. Measuring the color of enamel after brushing teeth to obtain L₂The change value of the enamel color before and after tooth brushing is calculated to be △ L so as to evaluate the whitening effect of each group of toothpaste samples on removing the extrinsic stains of the teeth, the larger the value of △ L is, the higher the whitening degree is, and the better the whitening effect is.

△L＝[(L₂-L₁)/L₁]×100％

△ the results of the calculation of the L value are shown in Table 1.

TABLE 1 EXAMPLES 1-12 test results of tooth whitening Performance

2. Friction value test

The test is carried out according to the GB/T35832-2018 detection method.

The test results are shown in Table 2.

TABLE 2 results of friction value test for examples 1 to 12

The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims

1. The whitening toothpaste is characterized by at least comprising the following components in percentage by weight: 10-40% of an abrasive, 0.1-5% of polyphosphate, 1-10% of pyrophosphate, 0.1-10% of hydroxyapatite, 0.001-0.50% of pearling agent, 0.5-4% of fluoride, 0.1-1.5% of thickening agent, 1-10% of sweetening agent, 0.01-2% of preservative, 0.1-0.5% of humectant, 1.5-6% of foaming agent and water to make up 100%.

2. The whitening toothpaste according to claim 1, wherein the abrasive is a combination of compound silica and pearl powder, and the weight ratio of the abrasive to the pearl powder is 1: (0.05-0.5).

3. The whitening toothpaste according to claim 2, wherein the compound silica is prepared by compounding silica I with the particle size of 1-30 μm and silica II with the particle size of 10-40 μm.

4. The whitening toothpaste according to claim 3, wherein the weight ratio of the silica I to the silica II is 1: (0.05-0.5).

5. The whitening toothpaste according to claim 2, wherein the pearl powder has a particle size of 0.1-10 μm.

6. The whitening toothpaste according to claim 1, wherein the weight ratio of polyphosphate to pyrophosphate is 1: (1-10).

7. The whitening toothpaste according to claim 1, wherein the weight ratio of polyphosphate to hydroxyapatite is 1: (1-10).

8. The whitening toothpaste according to claim 1, wherein the weight ratio of hydroxyapatite to fluoride is 1: (0.1-5).

9. The whitening toothpaste according to claim 1, wherein the hydroxyapatite has a particle size of 0.1 μm to 10 μm.

10. A method of preparing a whitening toothpaste according to any one of claims 1 to 9, characterized in that it comprises at least the following steps:

(1) mixing sorbitol and water, and stirring;