CN112315889A

CN112315889A - Eye essence cream and preparation method thereof

Info

Publication number: CN112315889A
Application number: CN202011287240.6A
Authority: CN
Inventors: 姚佃文
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-11-17
Filing date: 2020-11-17
Publication date: 2021-02-05

Abstract

The invention discloses an eye essence cream which is characterized by comprising the following components in parts by weight: 1-3 parts of astragalus sinicus flower extract, 0.5-2 parts of pipewort extract, 0.1-0.6 part of butterflybush flower extract, 2-5 parts of Chinese red sage extract, 0.5-1.5 parts of rosemary extract, 0.2-0.6 part of lemon extract, 0.5-1 part of safflower oil, 0.5-1 part of dendrobium officinale essential oil, 0.2-0.5 part of tomato essential oil, 0.5-1 part of egg white, 0.1-0.3 part of macelignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl choline phosphate copolymer, 2-5 parts of glycerol, 35-55 parts of water, 1-3 parts of emulsifier and 1-2 parts of functional Chinese herbal medicine extract. The invention also discloses a preparation method of the eye essence cream. The eye essence cream disclosed by the invention has the advantages of stable and good performance, long shelf life, obvious moisturizing, nourishing and anti-aging effects, capability of enhancing the activity of eye cells, capability of effectively inhibiting and improving the appearance of black eye circles and bags in eyes, high use safety and small toxic and side effects.

Description

Eye essence cream and preparation method thereof

Technical Field

The invention relates to the technical field of eye care, in particular to eye essence cream and a preparation method thereof.

Background

Eyes are a window of soul, are one of the most frequently used organs of a human body and are the weakest parts in the skin of the human body, and due to the lack of natural protection of a sebum membrane, various bad living habits, such as frequent use of electronic products, excessive use of eyes, carelessness for sun protection and maintenance, and the like, can cause eye fatigue, and various eye problems, such as dryness, water shortage, eye bags, black eyes, fishtail lines, and the like, can occur. Therefore, it is important to select a suitable eye care product.

Various eye care products appear in the market at present, but the quality of the eye care products is uneven, for example, the eye care products are not well absorbed, allergic, unobvious in effect and rebound in effect. Most of the products are products with a plurality of effects which are simply superposed, and the effects are very slight and difficult to achieve the expected effects. The eye essence cream is one of common skin care cosmetics, is used for protecting thinner skin around eyes, has a moistening effect, and has certain effects on pouches, black eyes, crow's feet, dry lines, fine lines and the like. Eye creams in the market at present generally have the defects of poor permeability, difficult absorption, unobvious use effect, single function, synthesis products of various chemical substances and possible damage to eye skin after long-term use.

The Chinese patent with the granted publication number of CN103385820B discloses a repair eye cream, aiming at providing an eye cream which has simple preparation method, triple wrinkle removing and long-acting and short-acting double synergistic repair function; the technical key points are as follows: the repair eye cream comprises the following components in percentage by mass: 1-10% of marine collagen; 1-20% of sweet almond protein; 1-5% of chondroitin sulfate; 1-3% of R-aminobutyric acid; 1-5% of phytosterol and 3-7% of glycerol; 3-7% of 1, 3-butanediol; 1-3% of dimethyl siloxane; 3-7% of squalene; 1-3% of jojoba oil; the balance of water; belongs to the technical field of daily chemical products, has good repairing effect, but has the problems of high cost, nervous toxicity and the like of R-aminobutyric acid and the like.

Therefore, the eye essence cream which has obvious moisturizing, nourishing and anti-aging effects, can enhance the activity performance of eye cells, effectively inhibits and improves the appearance of eye dark circles and under-eye puffiness meets the market demand, has wide market value and application prospect, and has very important significance for promoting the development of the eye-care cosmetic industry.

Disclosure of Invention

In view of the above, the present invention aims to provide an eye essence cream, which has stable and long shelf life, obvious moisturizing, nourishing and anti-aging effects, can enhance the activity of eye cells, effectively inhibit and improve the appearance of eye dark circles and eye bags, and has the advantages of high safety in use, small toxic and side effects, good absorption, good skin-friendly performance, and no allergy. Meanwhile, the invention also provides a preparation method of the eye essence cream, and the preparation method is simple and easy to implement, high in preparation efficiency and yield, low in preparation cost and suitable for continuous large-scale production.

In order to achieve the purpose, the invention adopts the technical scheme that:

the eye essence cream is characterized by comprising the following components in parts by weight: 1-3 parts of astragalus sinicus flower extract, 0.5-2 parts of pipewort flower extract, 0.1-0.6 part of butterflybush flower extract, 2-5 parts of Chinese red sage extract, 0.5-1.5 parts of rosemary extract, 0.2-0.6 part of lemon extract, 0.5-1 part of safflower oil, 0.5-1 part of dendrobium officinale essential oil, 0.2-0.5 part of tomato essential oil, 0.5-1 part of egg white, 0.1-0.3 part of macelignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl choline phosphate copolymer, 2-5 parts of glycerol, 35-55 parts of water and 1-3 parts of emulsifier.

Preferably, the eye essence cream further comprises: 1-2 parts of functional Chinese herbal medicine extract.

Preferably, the emulsifier is one or more of tween-80, tween-20 and polyoxyethylene vegetable oil.

Preferably, the preparation method of the myristyl lignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding myristolignan, N-allylnicotinamide, polyethylene glycol monoallyl ether, 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 3-5 hours at 70-80 ℃ in the atmosphere of nitrogen or inert gas, then precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 85-95 ℃ to constant weight to obtain the myristolignan/N-allylnicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer.

Preferably, the mass ratio of the myristyl lignan, the N-allyl nicotinamide, the polyethylene glycol monoallyl ether, the 2-methacryloyloxyethyl phosphorylcholine, the initiator and the high-boiling-point solvent is 1:0.5:3:0.5: (0.04-0.06):(15-25).

Preferably, the initiator is at least one of azobisisobutyronitrile and azobisisoheptonitrile.

Preferably, the high boiling point solvent is at least one of dimethyl sulfoxide, N-dimethylformamide, N-dimethylacetamide and N-methylpyrrolidone; the inert gas is any one of helium, neon and argon.

Preferably, the functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 2-5 parts of houttuynia cordata, 1-3 parts of carrot, 3-6 parts of selfheal, 2-4 parts of saxifrage, 3-5 parts of eclipta alba and 4-7 parts of Ruscus aculeatus roots.

Preferably, the preparation method of the functional Chinese herbal medicine extract comprises the following steps: mixing the raw materials, cleaning, cutting into pieces to obtain mixed raw materials, adding purified water 5-10 times of the mixed raw materials, decocting at 90-100 deg.C for 1-3 hr, filtering to obtain filtrate, and removing water by rotary evaporation to obtain Chinese herbal medicine extract.

Another object of the present invention is to provide a method for preparing the eye essence cream, which comprises the following steps: mixing the components in parts by weight, stirring for 15-20 minutes at the rotating speed of 35-45 revolutions per minute, then increasing the rotating speed to 3500-5300 revolutions per minute, homogenizing for 4-8 minutes, then reducing the rotating speed to 35-45 revolutions per minute, stirring for 25-35 minutes, then performing radiation sterilization, inspecting and packaging after passing the inspection, thus obtaining the eye essence cream.

Adopt the produced beneficial effect of above-mentioned technical scheme to lie in:

(1) according to the preparation method of the eye essence cream, the components are uniformly mixed according to the weight parts, a complex preparation process is not needed, the preparation method is simple and easy to implement, the dependence on equipment is low, the preparation efficiency and the yield are high, the preparation cost is low, and the preparation method is suitable for continuous large-scale production.

(2) The eye essence cream provided by the invention overcomes the technical problems that eye care products on the market at present are poor in absorption, allergic, unobvious in effect and rebound in effect, most of the products are products with simple and superposed effects, and the expected effect is difficult to achieve; the eye essence cream also overcomes the defects that eye creams in the current market generally have poor permeability, are not easy to absorb, are not obvious in using effect and single in function, are mostly synthesized products of various chemical substances, and can cause damage to eye skin after long-term use.

(3) According to the eye essence cream provided by the invention, most raw material components are natural, the toxic and side effects are low, the absorption effect of a human body is good, and the raw material components are reasonably matched and have synergistic effects, so that the eye essence cream can effectively reduce internal heat, expel toxin, diminish inflammation and relieve pain, obviously promote blood microcirculation of eyes, improve the blood flow effect of the eyes, reduce the accumulation of toxin in the eyes, enhance the nutrition of the eyes and play obvious effects of moisturizing, nourishing and resisting aging.

(4) The eye essence cream provided by the invention has the advantages that the addition of the myristolignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer can play a thickening role on one hand, in addition, through the interaction of electronic effect, steric effect and the like among the monomers, the prepared copolymer has better surface activity, improves the shape and appearance among the components, improves the performance stability and the quality guarantee period of the eye essence cream, and the monomers on the surface can act synergistically to play roles of resisting oxidation, resisting aging, eliminating free radicals, moisturizing and moisturizing skin, protecting skin, regulating and buffering PH and the like, and the monomers act synergistically, the essence box has a good eye protection effect, can enhance the activity performance of eye cells, and effectively inhibits and improves the appearance of black eye circles and eye bags.

(5) The natural components of the astragalus sinicus flower extract, the pipewort flower extract, the butterflybush flower extract, the horsetail herb extract, the rosemary extract and the lemon extract are safe, mild and effective, are suitable for eye thin skin, have a comprehensive conditioning effect on phenomena of fine lines, dark circles, looseness and the like which are easy to appear on eye skin, and have the effects of relieving the fatigue state of the eye skin, promoting microcirculation and activating skin cells. When the safflower oil, the dendrobium officinale essential oil, the tomato essential oil and the egg white act on the eye skin in a synergistic manner, the eye skin care product has good oxidation resistance and wrinkle resistance, and can repair the damage to the eye skin to a certain extent; effectively repair damaged epidermal cells and solve the eye problems of wrinkles, eye bags, edema and the like. The components have synergistic effect, can promote effective components to rapidly permeate into eye epidermal cells and penetrate into internal cells, activate eye skin, promote eye capillary microcirculation, remove free radicals, nourish and invigorate nutrition, promote skin metabolism, achieve the effects of comprehensively conditioning and relieving eye fatigue, improve eyesight, and prevent and treat various eye problems such as eye skin aging, dark circles and the like; the obtained eye essence cream has good compatibility with skin, is fresh and not greasy, and has remarkable moisturizing and water locking effects.

Detailed Description

In order to make the technical solutions of the present invention better understood and make the above features, objects, and advantages of the present invention more comprehensible, the present invention is further described with reference to the following examples. The examples are intended to illustrate the invention only and are not intended to limit the scope of the invention.

In the embodiment of the invention, the raw materials are all purchased commercially; .

Example 1

The eye essence cream is characterized by comprising the following components in parts by weight: 1 part of astragalus sinicus flower extract, 0.5 part of pipewort flower extract, 0.1 part of butterflybush flower extract, 2 parts of Chinese red sage extract, 0.5 part of rosemary extract, 0.2 part of lemon extract, 0.5 part of safflower oil, 0.5 part of dendrobium officinale essential oil, 0.2 part of tomato essential oil, 0.5 part of egg white, 0.1 part of myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer, 2 parts of glycerol, 35 parts of water and 1 part of emulsifier; the eye essence cream further comprises: 1 part of functional Chinese herbal medicine extract; the emulsifier is tween-80.

The preparation method of the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding the myristolein, the N-allyl nicotinamide, the polyethylene glycol monoallyl ether, the 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 3 hours at 70 ℃ in a nitrogen atmosphere, precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 85 ℃ to constant weight to obtain the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer.

The mass ratio of the myristyl lignan to the N-allyl nicotinamide to the polyethylene glycol monoallyl ether to the 2-methacryloyloxyethyl phosphorylcholine to the initiator to the high-boiling-point solvent is 1:0.5:3:0.5:0.04: 15; the initiator is azobisisobutyronitrile; the high boiling point solvent is dimethyl sulfoxide.

The functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 2 parts of heartleaf houttuynia herb, 1 part of carrot, 3 parts of selfheal, 2 parts of saxifrage, 3 parts of eclipta alba and 4 parts of Ruscus aculeatus root.

The preparation method of the functional Chinese herbal medicine extract comprises the following steps: mixing the raw materials, cleaning, cutting to obtain mixed raw materials, adding purified water with a mass 5 times of the mass of the mixed raw materials, decocting at 90 deg.C for 1 hr, filtering to obtain filtrate, and removing water by rotary evaporation to obtain Chinese herbal medicine extract.

The preparation method of the eye essence cream is characterized by comprising the following steps: mixing the components in parts by weight, stirring for 15 minutes at the rotating speed of 35 revolutions per minute, increasing the rotating speed to 3500 revolutions per minute, homogenizing for 4 minutes, reducing the rotating speed to 35 revolutions per minute, stirring for 25 minutes, performing radiation sterilization, inspecting, and packaging to obtain the eye essence cream.

Example 2

The eye essence cream is characterized by comprising the following components in parts by weight: 1.5 parts of astragalus sinicus flower extract, 0.9 part of pipewort flower extract, 0.2 part of butterflybush flower extract, 2.5 parts of Chinese red sage extract, 0.8 part of rosemary extract, 0.3 part of lemon extract, 0.7 part of safflower oil, 0.6 part of dendrobium officinale essential oil, 0.3 part of tomato essential oil, 0.7 part of egg white, 0.15 part of myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine phosphate copolymer, 2.5 parts of glycerin, 40 parts of water and 1.5 parts of emulsifier; the eye essence cream further comprises: 1.2 parts of functional Chinese herbal medicine extract; the emulsifier is tween-20.

The preparation method of the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding the myristolein, the N-allyl nicotinamide, the polyethylene glycol monoallyl ether, the 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 3.5 hours at 73 ℃ in a helium atmosphere, then precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 88 ℃ to constant weight to obtain the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer.

The mass ratio of the myristolignan to the N-allyl nicotinamide to the polyethylene glycol monoallyl ether to the 2-methacryloyloxyethyl phosphorylcholine to the initiator to the high-boiling-point solvent is 1:0.5:3:0.5: 0.045: 18; the initiator is azobisisoheptonitrile; the high boiling point solvent is N, N-dimethylformamide.

The functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 3 parts of heartleaf houttuynia herb, 1.5 parts of carrot, 4 parts of common selfheal fruit-spike, 2.5 parts of saxifrage, 3.5 parts of eclipta alba and 5 parts of Ruscus aculeatus root.

The preparation method of the functional Chinese herbal medicine extract comprises the following steps: mixing the raw materials, cleaning, cutting to obtain mixed raw materials, adding purified water with the mass 6 times of the mass of the mixed raw materials, decocting at 93 ℃ for 1.5 hours, filtering to obtain filtrate, and removing water by rotary evaporation to obtain the Chinese herbal medicine extract.

The preparation method of the eye essence cream is characterized by comprising the following steps: mixing the components in parts by weight, stirring for 17 minutes at the rotating speed of 38 revolutions per minute, then increasing the rotating speed to 4000 revolutions per minute, homogenizing for 5 minutes, then reducing the rotating speed to 38 revolutions per minute, stirring for 28 minutes, then performing radiation sterilization, inspecting and packaging to obtain the eye essence cream.

Example 3

The eye essence cream is characterized by comprising the following components in parts by weight: 2 parts of astragalus sinicus flower extract, 1.3 parts of pipewort flower extract, 0.4 part of butterflybush flower extract, 3.5 parts of gulfweed extract, 1 part of rosemary extract, 0.4 part of lemon extract, 0.7 part of safflower oil, 0.8 part of dendrobium officinale essential oil, 0.4 part of tomato essential oil, 0.7 part of egg white, 0.2 part of macelignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer, 3.5 parts of glycerol, 45 parts of water and 2 parts of emulsifier; the eye essence cream further comprises: 1.5 parts of functional Chinese herbal medicine extract; the emulsifier is polyoxyethylene vegetable oil.

The preparation method of the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding myristolein, N-allyl nicotinamide, polyethylene glycol monoallyl ether, 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 4 hours at 75 ℃ in an inert gas atmosphere, then precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 90 ℃ to constant weight to obtain a myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer; the mass ratio of the myristolignan to the N-allyl nicotinamide to the polyethylene glycol monoallyl ether to the 2-methacryloyloxyethyl phosphorylcholine to the initiator to the high-boiling-point solvent is 1:0.5:3:0.5: 0.05: 20; the initiator is azobisisobutyronitrile; the high boiling point solvent is N, N-dimethylacetamide; the inert gas is neon.

The functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 3.5 parts of heartleaf houttuynia herb, 2 parts of carrot, 4.5 parts of selfheal, 3 parts of saxifrage, 4 parts of eclipta alba and 5.5 parts of Ruscus aculeatus roots.

The preparation method of the functional Chinese herbal medicine extract comprises the following steps: mixing the raw materials, cleaning, cutting to obtain mixed raw materials, adding purified water with a mass 7.5 times of the mass of the mixed raw materials, decocting at 95 deg.C for 2 hr, filtering to obtain filtrate, and removing water by rotary evaporation to obtain Chinese herbal medicine extract.

The preparation method of the eye essence cream is characterized by comprising the following steps: mixing the components in parts by weight, stirring for 18 minutes at the rotating speed of 40 revolutions per minute, increasing the rotating speed to 4700 revolutions per minute, homogenizing for 6 minutes, reducing the rotating speed to 40 revolutions per minute, stirring for 30 minutes, performing radiation sterilization, inspecting, and packaging to obtain the eye essence cream.

Example 4

The eye essence cream is characterized by comprising the following components in parts by weight: 2.8 parts of astragalus sinicus flower extract, 1.8 parts of pipewort flower extract, 0.5 part of butterflybush flower extract, 4.5 parts of Chinese red sage extract, 1.4 parts of rosemary extract, 0.5 part of lemon extract, 0.9 part of safflower oil, 0.9 part of dendrobium officinale essential oil, 0.45 part of tomato essential oil, 0.9 part of egg white, 0.28 part of myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine phosphate copolymer, 4.5 parts of glycerol, 53 parts of water and 2.6 parts of emulsifier; the eye essence cream further comprises: 1.9 parts of functional Chinese herbal medicine extract; the emulsifier is formed by mixing tween-80, tween-20 and polyoxyethylene vegetable oil according to the mass ratio of 1:3: 5.

The preparation method of the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding the myristolein, the N-allyl nicotinamide, the polyethylene glycol monoallyl ether, the 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 4.8 hours at 78 ℃ in an inert gas atmosphere, then precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 93 ℃ to constant weight to obtain the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer.

The mass ratio of the myristolignan to the N-allyl nicotinamide to the polyethylene glycol monoallyl ether to the 2-methacryloyloxyethyl phosphorylcholine to the initiator to the high-boiling-point solvent is 1:0.5:3:0.5: 0.055: 23; the initiator is formed by mixing azodiisobutyronitrile and azodiisoheptonitrile according to the mass ratio of 3: 5; the high-boiling-point solvent is formed by mixing dimethyl sulfoxide, N-dimethylformamide, N-dimethylacetamide and N-methylpyrrolidone according to a mass ratio of 1:1:3: 2; the inert gas is argon.

The functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 4.5 parts of heartleaf houttuynia herb, 2.5 parts of carrot, 5.5 parts of selfheal, 3.5 parts of saxifrage, 4.5 parts of eclipta alba and 6.5 parts of Ruscus aculeatus root; the preparation method of the functional Chinese herbal medicine extract comprises the following steps: mixing the raw materials, cleaning, cutting into pieces to obtain mixed raw materials, adding purified water with a mass 9 times of that of the mixed raw materials, decocting at 98 deg.C for 2.8 hr, filtering to obtain filtrate, and removing water by rotary evaporation to obtain Chinese herbal medicine extract.

The preparation method of the eye essence cream is characterized by comprising the following steps: mixing the components in parts by weight, stirring for 19 minutes at the rotating speed of 43 revolutions per minute, then increasing the rotating speed to 5200 revolutions per minute, homogenizing for 7.5 minutes, then reducing the rotating speed to 43 revolutions per minute, stirring for 33 minutes, then performing radiation sterilization, inspecting and packaging to obtain the eye essence cream.

Example 5

The eye essence cream is characterized by comprising the following components in parts by weight: 3 parts of astragalus sinicus flower extract, 2 parts of pipewort flower extract, 0.6 part of butterflybush flower extract, 5 parts of Chinese red sage extract, 1.5 parts of rosemary extract, 0.6 part of lemon extract, 1 part of safflower oil, 1 part of dendrobium officinale essential oil, 0.5 part of tomato essential oil, 1 part of egg white, 0.3 part of macelignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer, 5 parts of glycerol, 55 parts of water and 3 parts of emulsifier; the eye essence cream further comprises: 2 parts of functional Chinese herbal medicine extract; the emulsifier is tween-80.

The preparation method of the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding the myristolein, the N-allyl nicotinamide, the polyethylene glycol monoallyl ether, the 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 5 hours at 80 ℃ in a nitrogen atmosphere, precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 95 ℃ to constant weight to obtain the myristolein/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer.

The mass ratio of the myristyl lignan to the N-allyl nicotinamide to the polyethylene glycol monoallyl ether to the 2-methacryloyloxyethyl phosphorylcholine to the initiator to the high-boiling-point solvent is 1:0.5:3:0.5:0.06: 25; the initiator is azobisisobutyronitrile; the high boiling point solvent is N-methyl pyrrolidone.

The functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 5 parts of heartleaf houttuynia herb, 3 parts of carrot, 6 parts of selfheal, 4 parts of saxifrage, 5 parts of eclipta alba and 7 parts of Ruscus aculeatus root.

The preparation method of the functional Chinese herbal medicine extract comprises the following steps: mixing the raw materials, cleaning, cutting to obtain mixed raw materials, adding purified water with the mass 10 times of the mass of the mixed raw materials, decocting at 100 deg.C for 3 hr, filtering to obtain filtrate, and removing water by rotary evaporation to obtain Chinese herbal medicine extract.

The preparation method of the eye essence cream is characterized by comprising the following steps: mixing the components in parts by weight, stirring for 20 minutes at the rotating speed of 45 revolutions per minute, increasing the rotating speed to 5300 revolutions per minute, homogenizing for 8 minutes, reducing the rotating speed to 45 revolutions per minute, stirring for 35 minutes, performing radiation sterilization, inspecting, and packaging to obtain the eye essence cream.

Comparative example 1

This example provides an eye essence cream, which has a formulation and a preparation method substantially the same as those of example 1, except that the milk vetch flower extract and the pipewort extract are not added.

Comparative example 2

This example provides an eye cream having substantially the same formulation and preparation method as example 1, except that no extract of Buddleja officinalis and red sage was added.

Comparative example 3

This example provides an eye cream having a formulation and a preparation method substantially the same as those of example 1, except that rosemary extract and lemon extract were not added.

Comparative example 4

The present example provides an eye essence cream, which has a formula and a preparation method substantially the same as those of example 1, except that safflower oil and dendrobium officinale essential oil are not added.

Comparative example 5

The present example provides an eye essence cream, which has a formula and a preparation method substantially the same as those of example 1, except that tomato essential oil and egg white are not added.

Comparative example 6

This example provides an eye essence cream, which has a formulation and a preparation method substantially the same as those of example 1, except that no myristyl lignan/N-allylnicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer is added.

Comparative example 7

This example provides an eye essence cream, which has a formulation and a preparation method substantially the same as those of example 1, except that no functional herbal extracts are added.

Acute skin toxicity tests, skin irritation tests and eye irritation tests were carried out on each product according to the procedure and method for evaluating cosmetic safety GB 7919-1987. For each experiment, 10 mice (SPF grade Balb/c mice, purchased from Guangdong provincial medical laboratory animal center, 8-10 weeks old, 18-22 g) were male and female. Acute skin toxicity test shows that the tested mouse has no death in 7 days, the fur is glossy and grows well, the skin is not red and swollen after the product is applied, and the product has no obvious toxicity to animal skin. Secondly, no erythema and edema appear at the position where the tested animal is smeared with the product; the skin irritation intensity is non-irritating. ③ the eyes of the tested animals are given to each product, 2 drops are given per day, 1 drop is given per time, the product is kept for 15 days, and the observation on the eyes of the tested mice shows that the eye abnormality exists, and the result shows that: the eye essence cream products related to the embodiments and the comparative examples of the invention have no irritant damage to the eyes of mice.

In order to further illustrate the beneficial technical effects of the embodiments of the present invention, the eye essence creams described in the embodiments 1 to 5 and the comparative examples 1 to 7 were subjected to performance evaluation, the evaluation results are shown in table 1, and the evaluation methods are as follows: the product of each example is used for carrying out eye protection effect test, the smearing part is skin around eyes, the channels and collaterals around eyes are massaged, the tested object is 40-50 years old, women with obvious eye problems such as eye bags, dark circles and the like are smeared twice in the morning and evening after each face cleaning, and the smearing amount of each time is 1mg/cm²Meanwhile, the eyes of the test subjects were followed up by gentle hand application for 1 month, and the number of the subjects per case was 40.

As can be seen from table 1, the eye essence cream disclosed in the examples of the present invention has better eye skin care effect than the comparative example, which is a result of the synergistic effect of the components.

TABLE 1

The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. The eye essence cream is characterized by comprising the following components in parts by weight: 1-3 parts of astragalus sinicus flower extract, 0.5-2 parts of pipewort flower extract, 0.1-0.6 part of butterflybush flower extract, 2-5 parts of Chinese red sage extract, 0.5-1.5 parts of rosemary extract, 0.2-0.6 part of lemon extract, 0.5-1 part of safflower oil, 0.5-1 part of dendrobium officinale essential oil, 0.2-0.5 part of tomato essential oil, 0.5-1 part of egg white, 0.1-0.3 part of macelignan/N-allyl nicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl choline phosphate copolymer, 2-5 parts of glycerol, 35-55 parts of water and 1-3 parts of emulsifier.

2. The eye essence cream according to claim 1, further comprising: 1-2 parts of functional Chinese herbal medicine extract.

3. The eye essence cream according to claim 1, wherein the emulsifier is one or more of tween-80, tween-20 and polyoxyethylene vegetable oil.

4. The eye essence cream according to claim 1, wherein the preparation method of the myristyl lignan/N-allylnicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer comprises the following steps: adding myristolignan, N-allylnicotinamide, polyethylene glycol monoallyl ether, 2-methacryloyloxyethyl phosphorylcholine and an initiator into a high-boiling-point solvent, stirring and reacting for 3-5 hours at 70-80 ℃ in the atmosphere of nitrogen or inert gas, then precipitating in acetone, and drying the precipitated polymer in a vacuum drying oven at 85-95 ℃ to constant weight to obtain the myristolignan/N-allylnicotinamide/polyethylene glycol monoallyl ether/2-methacryloyloxyethyl phosphorylcholine copolymer.

5. The eye essence cream according to claim 4, wherein the mass ratio of the myristyl lignan, the N-allyl nicotinamide, the polyethylene glycol monoallyl ether, the 2-methacryloyloxyethyl phosphorylcholine, the initiator and the high-boiling-point solvent is 1:0.5:3:0.5: (0.04-0.06):(15-25).

6. The eye cream as claimed in claim 4, wherein the initiator is at least one of azobisisobutyronitrile and azobisisoheptonitrile; the high boiling point solvent is at least one of dimethyl sulfoxide, N-dimethylformamide, N-dimethylacetamide and N-methylpyrrolidone; the inert gas is any one of helium, neon and argon.

7. The eye essence cream according to claim 1, wherein the functional Chinese herbal medicine extract is prepared from the following raw material medicines in parts by weight: 2-5 parts of houttuynia cordata, 1-3 parts of carrot, 3-6 parts of selfheal, 2-4 parts of saxifrage, 3-5 parts of eclipta alba and 4-7 parts of Ruscus aculeatus roots.

8. The eye essence cream as claimed in claim 7, wherein the preparation method of the functional herbal extract comprises the following steps: mixing the raw materials, cleaning, cutting into pieces to obtain mixed raw materials, adding purified water 5-10 times of the mixed raw materials, decocting at 90-100 deg.C for 1-3 hr, filtering to obtain filtrate, and removing water by rotary evaporation to obtain Chinese herbal medicine extract.

9. The eye essence cream according to any one of claims 1 to 8, wherein the preparation method of the eye essence cream comprises the following steps: mixing the components in parts by weight, stirring for 15-20 minutes at the rotating speed of 35-45 revolutions per minute, then increasing the rotating speed to 3500-5300 revolutions per minute, homogenizing for 4-8 minutes, then reducing the rotating speed to 35-45 revolutions per minute, stirring for 25-35 minutes, then performing radiation sterilization, inspecting and packaging after passing the inspection, thus obtaining the eye essence cream.