CN112168897A - Chinese patent medicine eye drops - Google Patents

Chinese patent medicine eye drops Download PDF

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Publication number
CN112168897A
CN112168897A CN202010562097.0A CN202010562097A CN112168897A CN 112168897 A CN112168897 A CN 112168897A CN 202010562097 A CN202010562097 A CN 202010562097A CN 112168897 A CN112168897 A CN 112168897A
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parts
raw materials
medicine
chinese patent
eye
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刘琪明
刘钜燊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/407Liver; Hepatocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a formula of a Chinese patent medicine eye drop, relates to the field of traditional Chinese medicine preparations and preparation methods thereof, and particularly relates to an eye drop prepared from traditional Chinese medicines. The method is characterized in that: the formula comprises the following components: 25-30 parts of bat dung (black shaxing), 30-35 parts of animal liver, 3-5 parts of edible fungus, 10-15 parts of moon ash, 3-5 parts of medlar and 8-10 parts of dogliver dish. Weighing the raw materials according to a certain weight ratio. The raw materials are taken from natural articles, and substances harmful to human bodies, such as preservatives, antibiotics, hormones and the like are never added, the raw materials are from homology of medicine and food, are brand new traditional Chinese medicine combinations which have not been appeared in the past, are good medicines for treating and preventing eye diseases, are suitable for conjunctivitis, pinkeye, trachoma, asthenopia, cataract and the like, have obvious treatment effect, are not easy to relapse, and are convenient and comfortable to use.

Description

Chinese patent medicine eye drops
[ technical field ] A method for producing a semiconductor device
The invention relates to a Chinese patent medicine, in particular to a traditional Chinese medicine formula of an eye medicine and a preparation method thereof.
[ background of the invention ]
Eyes are windows of soul, are important organs of people communicating with the society, however, with the development of high technology, the work and life of people are more and more diversified, the eyes are more frequently used, and in the life, work, study and even leisure time, electronic products are in contact with the life of people all the time, so that the burden of the eyes is increased, the frequent eye diseases of modern people are formed, the various causes of the diseases are caused, but the long-term face of computers, mobile phones, strong light and night-out is one of the most direct factors for causing the frequent eye diseases; moreover, when the healthy qi of the human body is insufficient, the resistance is weak, external wind-cold-evil invades the human body due to deficiency, flows through the channels and collaterals, blocks eyes and forms local refractory infection inflammation, and the local blood circulation is not smooth, so that the chronic disease cannot be cured. Eye diseases are classified into internal and external oculopathy eye diseases in medicine, and a plurality of eye medicines aiming at the eye diseases are available in the market at present, and although the eye medicines aim at different symptoms, the main components of the eye medicines are several: antiseptic, hormone, antibiotic and antiphlogistic ingredients have side effects, and although the use amount of the components is not large, the components do not harm eyes when being used occasionally, but the long-term use of the components does not relieve fatigue, improve eye diseases, but injure eyes and aggravate the disease condition.
[ summary of the invention ]
Aiming at the technical problems, the invention aims to provide a pure traditional Chinese medicine formula of an eye medicine which has the functions of promoting blood circulation to remove blood stasis, moistening eyes, continuously improving local blood circulation of eyes and invasion of pathogenic wind-cold and enhancing immunity, is safe and controllable, has stable property, and is a medicine without substances harmful to human bodies, such as preservatives, antibiotics, hormones and the like.
The technical problem solved by the invention is realized by adopting the following technical scheme: a traditional Chinese medicine formula of an ophthalmic medicine comprises the following raw material medicines: 6 kinds of the plant materials including the plant material including the; can also be made into tablet for administration; concentrating the decoction, vacuum drying to obtain crystal, and drinking with warm boiled water; grinding into fine paste, making into unguent, applying on canthus, and refining to make into injection for patients.
The effective range of the weight portion ratio of each medicine in the formula is 25-30 portions of bat dung (black shaxing), 30-35 portions of animal liver, 3-5 portions of edible fungus, 10-15 portions of yueshuang, 3-5 portions of medlar and 8-10 portions of dogliver dish:
the optimal weight part ratio of the medicines in the formula is as follows: 25 parts of bat dung (black sand star), 33 parts of animal viscera, 4 parts of agaric, 13 parts of moon ash, 4 parts of medlar and 9 parts of dogliver.
The medicine characteristics and effects of the invention are as follows:
and (3) luminous sand: pungent, slightly bitter and cold in nature, entering liver meridian, cooling and dispersing; the main components are as follows: contains cholesterol, urea, uric acid, vitamin A, etc.; the efficacy is mainly as follows: blindness, bromhidrosis, conjunctival congestion, leucorrhea with blood, nebula, heat-clearing, eyesight-improving, nebula-removing, blood stasis-removing, stagnation-removing, and malnutrition-removing; shape: oblong particles with two microtip ends, a length of 5-7 mm, a diameter of about 2 mm, rough surface, brown or gray brown, often broken, in the form of small granules or powder; the producing area: heilongjiang, Jilin, Liaoning, Hebei, Fujian, Guangdong, Guangxi, Hunan, Hubei, Sichuan, Shanxi, Gansu, etc.
Animal liver, liver of porcine animals: sweet and bitter in flavor, warm in nature, entering liver meridian; the main components are as follows: every 100 g of pork liver contains: contains 21.3 g of protein, 4.5 g of fat, 1.4 g of carbohydrate, 11 mg of calcium, 270 mg of phosphorus, 25.0 mg of iron, 5.78 mg of zinc, 0.40 mg of thiamine, 2.11 mg of riboflavin, 16.2 mg of nicotinic acid and 18 mg of ascorbic acid; the efficacy is mainly as follows: has effects in nourishing liver, improving eyesight, nourishing blood, tonifying blood, removing toxin, and enhancing immunity, and can be used for treating blood deficiency, chlorosis, nyctalopia, and conjunctival congestion. The producing area: all over the land.
And (3) edible fungus: it is neutral in nature and sweet in flavor, enters stomach and large intestine meridians, and is preferably Auricularia. The main components are as follows: iron, calcium, phosphorus, vitamin B1, and the like; the efficacy is mainly as follows: has effects in cooling blood, stopping bleeding, regulating blood, nourishing yin, invigorating qi, moistening lung, nourishing yin, moistening dryness, caring skin, invigorating stomach, invigorating spleen, resisting blood coagulation, resisting thrombosis, reducing blood lipid, softening blood vessel, and promoting blood circulation. Shape: the black and brown color paste is irregular and flaky, is more curled, has smooth surface and lighter black and brown color, expands after being soaked in water, turns light color, is soft, moist and slightly transparent, and has smooth mucus on the surface.
Grey in the moon: slightly bitter and cool in nature; the main components are as follows: potassium carbonate and carbon; the efficacy is mainly as follows: has effects of stopping bleeding, invigorating stomach, promoting fluid production, resisting anoxia, enhancing disease resistance, and promoting protein synthesis. Shape: black powder, no greasy feeling, and no odor.
Medlar: sweet in taste; neutral in nature, entering liver, kidney and lung meridians; the main components are as follows: fat, protein, free amino acids, taurine, betaine, vitamin B1, B2, E, C, especially high carotenoid content; the efficacy is mainly as follows: nourishing liver and kidney, improving eyesight, strengthening body resistance, consolidating constitution, promoting fluid production, replenishing marrow, nourishing yin, invigorating kidney, invigorating qi, tranquilizing mind, strengthening body constitution, and delaying aging. The medlar is a good medicine, can effectively strengthen various viscera functions, improve brain functions, resist free radicals and delay senility.
Dogliver dish: cool in nature, sweet and bland in flavor; entering heart, liver, large intestine and small intestine meridians; the efficacy is mainly as follows: deficiency of liver and kidney, dizziness, blurred vision, nourishing liver, replenishing kidney essence, moistening lung, clearing away heat and toxic materials, cooling blood, and preventing and treating fever macula, summer heat polydipsia, conjunctivitis, laryngopharynx swelling and pain, and furuncle. The producing area: fujian, Taiwan, Guangdong, Guangxi, Henan, northeast, Hebei, Shanxi, Shaanxi, Ningxia, Gansu, Qinghai and other places.
The process comprises the following steps: the reasonable and feasible decocting process is preferred, and the active ingredients of all the substances can be dissolved in water and are stable to damp heat.
(1) Selecting material particles: cleaning impurities in the night vision sand, winnowing to remove mud and sand, or rinsing and then drying in the sun; packing and wrapping the ash in a cotton bag; cleaning the agaric; cutting herba Setariae viridis into pieces; selecting fresh animal livers, slicing, wherein all materials do not contain mucus and starch substances and are not easy to coke and bottom burnt;
(2) in order to fully extract the effective components, the medicines are decocted firstly: soaking faeces Vespertilionis, Auricularia, rhizoma Cynanchi Otophylli for 20-30 min, adding animal liver, boiling with strong fire, and decocting with slow fire;
(3) the water adding amount of the soaking is 4-6 times of the material;
(4) decocting the medicines later: in order to avoid the problem that the material is easy to decompose and damage after being heated for too long time: the medicines are required to be decocted firstly until the last 10 minutes, and medlar is added for decoction.
(5) The decoction time is 30-50 minutes; decocting for 2 times;
(6) decocting for the second time, wherein the warm water amount is two thirds of the first water amount, decocting for 30 minutes with slow fire after boiling with strong fire, filtering out the filtrate respectively, and combining the filtrates obtained by decocting for two times to obtain a mixed solution with the total amount of one fourth of the total water amount;
the scheme does not generate precipitation reaction during mixing and decocting.
Obtained from the experiment: the scheme has the advantages that the effective components are mixed to obtain the main elements beneficial to eyes: selenium element, protein, flavone, polysaccharide, polyphenol ferroferric oxide, carbon black, carbonate, nitrogen, phosphorus, potassium, calcium, magnesium, carotene, betaine, carotene, zeaxanthin, nicotinic acid, amino acid and other trace elements, fat, fatty acid, vitamins and other components, and has the functions of improving eyesight, removing nebula, nourishing liver, replenishing blood, removing toxin, nourishing kidney, cooling blood, stopping bleeding, softening blood vessels, strengthening body resistance, consolidating constitution, repairing focus of infection, and recovering vision naturally.
[ detailed description ] embodiments
Eye drops were prepared according to formulations 1, 2 and 3 of example 1.
Dropping 0.1ml of eye drop into right conjunctival sac of female and male rabbits respectively for 15 times to passively close upper and lower eyelids for 1s, making the other eye for self-control, dropping into object for 1h, 24h, 48h, 72h, and 4 th and 7 th days, observing eye irritation reaction condition, and recording eye irritation reaction integral according to eye injury grading standard
Category of formulation Dosage used Number of animals Cornea 1 Iris (iris) Congestion of blood Integration
1 0.1ml 10 0 0 0 0
2 0.1ml 10 () 0 0 0
3 0.1ml 10 0 0 0 ()
The experimental results are as follows: the eye of the animal has no irritative symptoms, and the result shows that the eye drop has no irritative to eyes.
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Inspection references' evaluation procedure and inspection method of health food functionality
Medicine and food additive
The ophthalmic decoction prepared according to example 1 was taken.
Example one
The Chinese patent medicine eye drop consists of the following raw materials in parts by weight: 25 parts of bat dung (black sand star), 33 parts of animal liver, 3 parts of edible fungus, 10 parts of moon ash, 3 parts of medlar and 8 parts of dogliver.
Weighing the 6 raw materials according to a certain weight ratio, decocting to prepare an eye medicine decoction, an oral liquid, a tablet and a wax pill, concentrating the decoction, drying in vacuum to obtain a crystal, instantly dissolving with warm boiled water for drinking, preparing into an ointment for external application, and refining to prepare an injection for patients to inject.
The invention has the beneficial effects.
Compared with the prior art, the Chinese patent medicine eye drop provided by the invention has the advantages that the raw materials are selected from natural animals and plants, and the prepared raw materials are homologous in medicine and food, so that the property of the medicine is not . In order to implement the development of the traditional Chinese medicine, the traditional Chinese medicine improves the disease resistance of the human body by improving the internal environment of the human body, and treats the disease naturally.
Case 1
Liu Yi, male, 70 years old, people in Zhongshan city have red and swollen eyes, pain, turbid eye crystals and blurred vision, the treatment lasts for many years, the effect is not obvious, and the symptoms are repeated, the medicine can be recovered after being used for two weeks, and the medicine can be kept good for 20 years at present.
Case 2
In the case of a certain forest, women, age 76, people in Sterculia, eye pain, lacrimation in the wind and conjunctival congestion, the treatment in the hospital for a plurality of years does not improve before, and the disease can be cured by using the medicine for three weeks.
Case 3
Wangzhi, male, 30 years old, Zhongshan City, red and swollen eyes, pain and conjunctival congestion, and symptoms are not improved for years, and the disease is cured after the medicine is used for two weeks.
Case 4
Plum, male, 8 years old, Zhongshan City, hyperemia of eye and cornea, pain and itching, and more than ten days of disease, the treatment in hospital is not improved, and the disease can be cured after taking the medicine for one week.
When people suffer from eye diseases, hundreds of patients take the prescription to get well.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (3)

1. The Chinese patent medicine eye drop is characterized by comprising the following raw materials in parts by weight: 25-30 parts of bat dung (black shaxing), 30-35 parts of animal liver, 3-5 parts of edible fungus, 10-15 parts of moon ash, 3-5 parts of medlar and 8-10 parts of dogliver dish.
2. The Chinese patent medicine eye drop is characterized by comprising the following raw materials in parts by weight: 25 parts of bat dung (black sand star), 33 parts of animal liver, 4 parts of edible fungus, 13 parts of moon ash, 4 parts of medlar and 9 parts of dogliver.
3. The Chinese patent medicine eye drops are characterized in that the eye drops are prepared by extracting liquid from raw materials, and are prepared into eye drop decoction, oral liquid, tablets and wax pills, the decoction is concentrated and dried in vacuum to form crystals, the crystals can be instantly drunk by warm boiled water, the ointment can be prepared for external application, and the ointment can be prepared into injection for patients after extraction.
CN202010562097.0A 2019-07-04 2020-06-10 Chinese patent medicine eye drops Pending CN112168897A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019106171872 2019-07-04
CN201910617187 2019-07-04

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CN112168897A true CN112168897A (en) 2021-01-05

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102698079A (en) * 2012-06-19 2012-10-03 成都中医药大学附属医院 Medicine composition for treating xerophthalmia and preparation method and application thereof
CN105726697A (en) * 2016-03-25 2016-07-06 甘肃东方天润玫瑰科技发展有限公司 Anti-asthenopia rose composition, eye drop and preparation method of anti-asthenopia rose composition
CN106728322A (en) * 2016-12-14 2017-05-31 周桂荣 It is a kind of to treat ointment of eye disease and preparation method thereof
CN106806349A (en) * 2015-11-30 2017-06-09 湖南恒生制药股份有限公司 Puerarin freeze-drying powder-injection and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102698079A (en) * 2012-06-19 2012-10-03 成都中医药大学附属医院 Medicine composition for treating xerophthalmia and preparation method and application thereof
CN106806349A (en) * 2015-11-30 2017-06-09 湖南恒生制药股份有限公司 Puerarin freeze-drying powder-injection and preparation method thereof
CN105726697A (en) * 2016-03-25 2016-07-06 甘肃东方天润玫瑰科技发展有限公司 Anti-asthenopia rose composition, eye drop and preparation method of anti-asthenopia rose composition
CN106728322A (en) * 2016-12-14 2017-05-31 周桂荣 It is a kind of to treat ointment of eye disease and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
无: "眼科专家推荐中医养眼妙方", 《社区医学杂志》 *

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