CN106728322A - It is a kind of to treat ointment of eye disease and preparation method thereof - Google Patents

It is a kind of to treat ointment of eye disease and preparation method thereof Download PDF

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Publication number
CN106728322A
CN106728322A CN201611149329.XA CN201611149329A CN106728322A CN 106728322 A CN106728322 A CN 106728322A CN 201611149329 A CN201611149329 A CN 201611149329A CN 106728322 A CN106728322 A CN 106728322A
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parts
ointment
borneol
moschus
root
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周桂荣
张海梁
王喜臣
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/413Gall bladder; Bile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nutrition Science (AREA)
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  • Medicinal Preparation (AREA)

Abstract

Ointment of eye disease and preparation method thereof is treated the invention discloses a kind of, mainly it is formulated by tinosporae, radix rehmanniae recen, carp gall, sheep courage, borneol, the root of kudzu vine, Moschus, its weight is 13 parts of tinosporae, 12 parts of radix rehmanniae recen, 0.5 2 parts of carp gall, 1 1.5 parts of sheep courage, 0.2 0.8 parts of borneol, 13 parts of the root of kudzu vine, 0.1 0.5 parts of Moschus;Golden fruit is pulled, radix rehmanniae recen, the root of kudzu vine mix processing and extract, and carp gall, sheep courage are blended into after removing slag, and cream is boiled into long, then be blended into borneol, Moschus, placed 24 hours under normal temperature, liquid dilute cream is obtained.Ointment is directly spread on eyelid and surrounding skin surface, ointment can discharge its active ingredient, and by the conduction of human acupoint, stimulate circulation and metabolism, accelerate the discharge of eye free radical, contribute to eye fatigue of releiving, oxygen and blood supply around lifting eyes, so as to reach the various eye diseases for the treatment of, improve the effect of various ophthalmic uncomfortables.

Description

It is a kind of to treat ointment of eye disease and preparation method thereof
Technical field
It is specifically a kind of to treat ointment of eye disease and preparation method thereof the present invention relates to a kind of medical cream.
Background technology
Outer disease is controlled in needing, and interior disease can also be controlled outward.The eyes are the windows of the mind, with interior in internal organs on physiology, pathology It is closely related.Illness in eye outer treating method is the important component of TCM Ophthalmology treatment means, by the height of successive dynasties traditional Chinese medical science scholar Pay attention to.Eyes local treatment is the affected area that medicine is directly acted on eyes, and few with consumption, local concentration is high, Yi Jiquan Body has no side effect, and can fully absorb, and plays its effective ingredient, reaches the irreplaceable effect of medicine for oral administration.
The content of the invention
Present invention offer is a kind of to treat ointment of eye disease and preparation method thereof.
A kind of ointment for treating eye disease, mainly by tinosporae, radix rehmanniae recen, carp gall, sheep courage, borneol, the root of kudzu vine, Moschus Be formulated, its weight be tinosporae 1-3 parts, radix rehmanniae recen 1-2 parts, carp gall 0.5-2 parts, 1-1.5 parts of sheep courage, borneol 0.2-0.8 parts, root of kudzu vine 1-3 parts, Moschus 0.1-0.5 parts;Preferred weight part proportioning is 1 part of tinosporae, 1 part of radix rehmanniae recen, carp gall 1 Part, 1 part of sheep courage, 0.5 part of borneol, 1 part of the root of kudzu vine, 0.2 part of Moschus.
The pharmacology of medicine used is as follows in above-mentioned ointment:
Golden fruit pulls, menispermaceae liana, its dried root bitter, cold in nature, enters lung and large intestine channel, and ophthalmology is used for heat-clearing solution Poison.
Radix rehmanniae recen, Scrophulariaceae herbaceos perennial, its root is sweet, cold in nature, enters conscience kidney channel, because of sweet Han Zhirun, therefore tool There are clearing heat and cooling blood, nourishing Yin and promoting production of body fluid;Ophthalmology be mainly used in treating and alleviate fundus hemorrhage, subconjuctival hemorrhage, intraocular it is dry and astringent, Depending on the thing dusk symptom such as vast, effect that red enriching yin improving eyesight is moved back in cooling blood and hemostasis, cool blood is played.
Carp gall, the courage of Cyprinidae animal carp, bitter, cold in nature, enter liver heart the spleen channel, with clearing heat for detumescence, removing nebula Effect;In ophthalmology primary treatment and alleviate red eye, swell pain, black eyeball ocular, fear day photophobia, pain and the symptom such as shed tears.
Sheep courage, bovid goat or sheep, dried courage, bitter, cold in nature, enter liver gallbladder channel, with relieving inflammation or internal heat, improving eyesight, The effect of removing toxic substances;Ophthalmology be mainly used in treating and alleviate pinkeye it is sudden and violent it is red, swell and ache shed tears, the symptom such as black eye ocular, play promoting blood circulation Effect of improving eyesight.
Borneol, the processed goods of Dipterocarpaceae plant Borneolum Syntheticum resin, taste is pungent hardship, cold nature, fragrance are strong, enter heart spleen and lung Through with inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain, going the effect of screen improving eyesight;It is mainly used in treating and alleviating the diseases such as red eye, swell pain in ophthalmology Shape, plays heat-clearing and moves back effect that is red, going screen improving eyesight, lead to all keys.
The dry root of the root of kudzu vine, the perennial defoliation liana elegant jessamine of pulse family or Gan Geteng, it is acrid-sweet flavor, cool in nature, enter taste warp; Be mainly used in treating and alleviate the symptoms such as dry hot eyes, hyperemia of bulbar conjunctiva, eye socket pain in ophthalmology, play promoting blood circulation and removing blood stasis, expelling pathogenic factors from muscles and skin bring down a fever, Effect that dispelling wind relieves the pain, ocular circulation is improved with this, increases eye nutrition, is kept the skin wet to skin near the eyes.
Secretion is dried in Moschus, animal in deer family horse musk deer or former musk deer hero body note capsule, taste is pungent, warm in nature, fragrance are strong, enter the heart The spleen channel, with inducing resuscitation of having one's ideas straightened out, invigorate blood circulation, swelling and pain relieving, removing nebula for improving eyesight effect;It is mainly used in treating and alleviating eye in ophthalmology The symptoms such as bottom train of thought obstruction, play it is promoting blood circulation and removing obstruction in channels, move back that screen block removing, clearing heat for detumescence, hygroscopic be antipruritic, scattered stasis pain effect.
The application method of above-mentioned ointment is directly to be externally applied to eyelid and its surrounding skin surface, each external application 20-30 minutes.
A kind of preparation method of above-mentioned ointment, golden fruit is pulled, radix rehmanniae recen, the root of kudzu vine mix to process and extract, and carp is blended into after removing slag Fish courage, sheep courage, are boiled into cream long, then are blended into borneol, Moschus, are placed 24 hours under normal temperature, and liquid dilute cream is obtained;Preferably, it is blended into Sealed after borneol, Moschus, under normal temperature and placed 24 hours.
Ointment is directly spread on eyelid and surrounding skin surface, ointment can discharge its active ingredient, and by human body acupoint The conduction in cave, stimulates circulation and metabolism, accelerates the discharge of eye free radical, contributes to eyes to keep fresh feel, Releive eye fatigue, oxygen and blood supply around lifting eyes, so as to reach the various eye diseases for the treatment of, improve various eyes The uncomfortable effect in portion;Topical ocular administration, it is not necessary to by digestive system, hence without toxic and side effect.
Modern medicine it has been proved that more than 90% eye disease is all eyes water shortage, anoxic or ischemic and causes, because And use the medicine preparation with the effects such as clearing heat and detoxicating, dispersing swelling and dissipating binds, blood-activating analgetic, nourshing blood and promoting blood circulation, dispelling wind and arresting itching Ointment, is externally applied to eye, the problems such as can improve ocular ischemic, water shortage, anoxic, recovers the vigor of skin near the eyes, and enhancing eye is micro- Circulation, help excludes toxin, promotes cell metabolism near the eyes unobstructed.
To verify that ointment of the present invention, to the therapeutic effect of various eye diseases, clinic is carried out with 100 persons suffering from ocular disorders Experiment, takes appropriate ointment and spreads on eyelid and its surrounding skin surface every time, and each external application 30 minutes three times a day, is continuously used 28 days.
Result of the test:The dry and astringent symptom of eye of 45 patients with dry eye is all effectively alleviated;30 muscae volitantes patients, After eighty per cant patient's use, symptom takes an evident turn for the better, and after one one-tenth patient's use, symptom is slightly alleviated;25 unclear trouble of eye-blurred Person, after ninety percent patient's use, eyesight be improved significantly.
Specific embodiment
With reference to specific embodiment, the present invention is further detailed explanation.Embodiments of the invention are to show Be given for the sake of example and description, and be not exhaustively or limit the invention to disclosed form.Many modifications and Change is for the ordinary skill in the art obvious.Selection and description embodiment are to more preferably illustrate this The principle and practical application of invention, and make one of ordinary skill in the art it will be appreciated that the present invention so as to design be suitable to it is specific The various embodiments with various modifications of purposes.
Embodiment 1
A kind of ointment for treating eye disease, mainly by tinosporae, radix rehmanniae recen, carp gall, sheep courage, borneol, the root of kudzu vine, Moschus It is formulated, its weight is tinosporae 10g, radix rehmanniae recen 10g, carp gall 5g, sheep courage 10g, borneol 2g, root of kudzu vine 10g, musk deer Fragrant 1g.
10g gold fruits are pulled, 10g radix rehmanniae recens, the 10g roots of kudzu vine mix processing and extract, and carp gall 5g, sheep courage 10g are blended into after removing slag, Long cream is boiled into, then be blended into borneol 2g, Moschus 1g, is placed 24 hours under normal temperature, liquid dilute cream is obtained.
Embodiment 2
A kind of ointment for treating eye disease, mainly by tinosporae, radix rehmanniae recen, carp gall, sheep courage, borneol, the root of kudzu vine, Moschus It is formulated, its weight is tinosporae 9g, radix rehmanniae recen 6g, carp gall 6g, sheep courage 4.5g, borneol 2.4g, root of kudzu vine 9g, musk deer Fragrant 1.5g.
9g gold fruits are pulled, 6g radix rehmanniae recens, the 9g roots of kudzu vine mix processing and extract, and carp gall 6g, sheep courage 4.5g are blended into after removing slag, long Cream is boiled into, then is blended into borneol 2.4g, Moschus 1.5g, placed 24 hours under normal temperature, liquid dilute cream is obtained.
Embodiment 3
A kind of ointment for treating eye disease, mainly by tinosporae, radix rehmanniae recen, carp gall, sheep courage, borneol, the root of kudzu vine, Moschus Be formulated, its weight be tinosporae 10g, radix rehmanniae recen 10g, carp gall 10g parts, sheep courage 10g, borneol 5g, the root of kudzu vine 10g, Moschus 2g.
10g gold fruits are pulled, 10g radix rehmanniae recens, the 10g roots of kudzu vine mix processing and extract, and carp gall 10g, sheep courage are blended into after removing slag 10g, is boiled into cream long, then is blended into borneol 5g, Moschus 2g, is sealed under normal temperature and placed 24 hours, and liquid dilute cream is obtained.
Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.It is based on Embodiment in the present invention, this area and the those of ordinary skill in the related art institute on the premise of creative work is not made The every other embodiment for obtaining, should all belong to the scope of protection of the invention.

Claims (5)

1. a kind of ointment for treating eye disease, it is characterised in that:It is main by tinosporae, radix rehmanniae recen, carp gall, sheep courage, borneol, The root of kudzu vine, Moschus are formulated, and its weight is tinosporae 1-3 parts, radix rehmanniae recen 1-2 parts, carp gall 0.5-2 parts, sheep courage 1- 1.5 parts, borneol 0.2-0.8 parts, root of kudzu vine 1-3 parts, Moschus 0.1-0.5 parts.
2. it is according to claim 1 treatment eye disease ointment, it is characterised in that:Its weight is tinosporae 1 Part, 1 part of radix rehmanniae recen, 1 part of carp gall, 1 part of sheep courage, 0.5 part of borneol, 1 part of the root of kudzu vine, 0.2 part of Moschus.
3. it is according to claim 1 and 2 treatment eye disease ointment, it is characterised in that:Its application method is directly outer Spread on eyelid and its surrounding skin surface, each external application 20-30 minutes.
4. described in a kind of claim 1 treatment eye disease ointment preparation method, it is characterised in that:Golden fruit is pulled, is given birth to Glutinous rehmannia, root of kudzu vine mixing are processed and extracted, and carp gall, sheep courage are blended into after removing slag, and cream is boiled into long, then are blended into borneol, Moschus, normal temperature decentralization Put 24 hours, liquid dilute cream is obtained.
5. ointment and preparation method thereof for the treatment of eye disease according to claim 4, it is characterised in that:Be blended into borneol, Sealed after Moschus, under normal temperature and placed 24 hours.
CN201611149329.XA 2016-12-14 2016-12-14 It is a kind of to treat ointment of eye disease and preparation method thereof Pending CN106728322A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112168897A (en) * 2019-07-04 2021-01-05 刘琪明 Chinese patent medicine eye drops

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
刘建平: "《糖尿病吃什么速查》", 30 June 2015, 中国纺织出版社 *
杨建宇等: "《一本书读懂偏方验方治病》", 30 April 2013, 中原出版传媒集团 中原农民出版社 *
梁繁荣: "《针灸学》", 31 August 2016, 中国中医药出版社 *
泄峰桂林主人: "《普济内外全书》", 30 November 2016, 中国中医药出版社 *
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贺振泉等: "《现代家庭医疗保健全书》", 31 October 1996, 广东经济出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112168897A (en) * 2019-07-04 2021-01-05 刘琪明 Chinese patent medicine eye drops

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